198 results about "Bacterial growth" patented technology

The invention discloses an antibacterial peptide PA targeting multi-drug-resistant gram-negative bacteria and application of the antibacterial peptide PA, and the amino acid sequence of the antibacterial peptide PA is shown as SEQ ID NO.1. The antibacterial peptide PA provided by the invention has a remarkable antibacterial effect of the multi-drug-resistant gram-negative bacteria, is quick in bactericidal effect, does not have hemolysis and cytotoxicity, does not cause renal toxicity after treatment, and can be used for preparing the antibacterial peptide PA for treating the multi-drug-resistant gram-negative bacteria. The biological safety is good, and the compound can be used for treating bacterial infection and can also be applied to other scenes needing sterilization or bacterial growth inhibition.

Provided a method for promoting growth of bacteria of the genus Bifidobacterium. The method for promoting growth of bacteria of the genus Bifidobacterium includes subjecting a milk culture medium containing one or more selected from the group consisting of cysteine, cystine, and a salt thereof to heat treatment and then culturing bacteria of the genus Bifidobacterium in the milk culture medium.

The invention provides an observation device of a bacterial incubator, and relates to the field of bacterial culture. A box door is rotationally connected to a box opening of the bacterial incubator main body, and three rectangular through holes are uniformly formed in the front end surface of the box door; three supporting shelves are uniformly mounted in the bacterial incubator main body; the device is characterized in that the front end of the box door is located at the front sides of the three rectangular ports and is rotationally connected with three transparent observation plates; through cooperation of the treading type driving assembly and the fog scraping assembly, when fog generated on the rear end face of the transparent observation plate needs to be scraped off, the box door does not need to be opened, the situation that the box door is frequently opened is avoided, and therefore normal growth of bacteria is prevented from being affected; the problems that in the using process of an observation window on an existing bacterial incubator door, when mist on the inner side face of the observation window needs to be scraped off, the whole incubator door needs to be opened, and normal growth of bacteria is affected when the incubator door is frequently opened are solved.

The present invention pertains to use of sodium diacetate (NaHAC2) as an antimicrobial agent against bacteria growing in biofilms. The aspects of the invention include a wound care product comprising sodium diacetate, a kit comprising a wound care product, and a method of treating an infected wound.

Provided is a composition for inhibiting the proliferation of bacteria belonging to the genus Collinsella, the composition containing at least one selected from sugar acid-containing oligosaccharides and salts thereof. The sugar acid is preferably selected from aldonic acid, uronic acid, and aldaric acid.

The invention discloses an intelligent distribution scheduling method and device for egg products and a medium, and relates to the technical field of intelligent scheduling, and the method comprises the steps: collecting biological characteristic parameters of target egg products in real time, carrying out the feature encryption processing through an edge calculation node to form private data packets, receiving the private data packets of all suppliers through a message queue service, and sending the private data packets to a server; calling a homomorphic encryption library to execute weighted average aggregation on the encrypted feature vectors; and loading real-time road condition data, compartment temperature and humidity distribution and a vibration spectrum in a digital twin sandbox based on a global egg rheology knowledge graph and a microbial growth kinetic model, and coupling to solve a product risk value of a protein shear stress accumulation equation and a flora growth equation. By constructing a global egg product rheology knowledge graph and a microbial growth kinetic model, the time-space coupling characteristics of biomechanical characteristics and microbial activity of egg products in transportation are accurately captured, and the quality risk quantification precision and the transportation strategy reliability are improved.

The application belongs to the technical field of microorganisms, and particularly discloses application of Bifidobacterium longum subsp. longum CGMCC No. 20105 in bacteriostasis. The application discloses for the first time that the Bifidobacterium longum subsp. longum strain CGMCC No. 20105 has the ability to ferment TPY or MRS to synthesize bacteriostatic substances, and the fermentation liquor has certain inhibitory effect on intestinal pathogenic bacteria, oral pathogenic bacteria, environmental pathogenic bacteria and antibiotic-resistant microorganisms. More importantly, the fermentation product does not affect the survival performance of conventional probiotics, indicating that the bacteriostatic substances synthesized by the Bifidobacterium longum subsp. longum strain CGMCC No. 20105 fermentation have certain safety, specificity and pertinence. Compared with other MRS fermentation strains, the bacteriostatic effect of the MRS fermentation liquor of the Bifidobacterium longum subsp. longum strain CGMCC No. 20105 is remarkable, and therefore has potential application value.

This invention discloses a residual liquid removal structure and method for an eye dropper, comprising: a bottle body, a dropper shell, a dropper column, and an annular sealing gasket. The dropper shell is connected to the bottle body and has a flow channel. An outlet is located at the top of the flow channel, and an annular sealing gasket is located at the connection between the outlet and the flow channel. The dropper column is located within the flow channel of the dropper shell, and includes a T-shaped section and a conical section. The conical section passes through the annular sealing gasket and the outlet and extends outward from the dropper shell. The inner ring of the annular sealing gasket is sealed to the outer wall of the conical section. Several guide grooves are evenly distributed on the dropper column. The advantages of this invention are: after dispensing, releasing the bottle body pushes the liquid film adhering to the conical section of the dropper column and the liquid suspended at the end of the conical section away from the conical section, allowing it to be dispensed into the user's eye without waste. Furthermore, it keeps the conical section exposed to air dry, thus preventing bacterial growth.

Antimicrobial eyewear features frames infused with or coated with antimicrobial additives, thereby offering continuous protection by actively destroying and inhibiting the growth of bacteria, fungi, parasites, and some viruses. The lenses may also have an antibacterial coating that destroys and inhibits bacterial growth. In some examples, the lenses are treated with a specialized strengthening liquid, wherein the liquid contains nano components that release heavy metal ions capable of invading the cell walls of bacteria, leading to bacterial elimination, destroying DNA molecules and proteases within the bacterial cells, denature viral proteins, break DNA chains, and result in cell death. Additionally, the strengthening liquid reduces dehydrogenase activity and interacts with various protein groups within the cell, thereby reducing the activity of these groups and effectively inhibiting the growth of E. coli and other bacteria on the lens surface.

The present utility model provides a gas purification device. The gas purification device comprises a main machine assembly and a filter assembly. The main machine assembly comprises a machine body and a rotating member rotationally arranged in the machine body, and the rotating member is arranged at a lower opening of the machine body. The filter assembly comprises a dust collection cylinder and a cyclone cone arranged in the dust collection cylinder; the dust collection cylinder is connected to the lower part of the machine body; the side wall of the dust collection cylinder is provided with an air inlet; a first airflow cavity channel is formed between the dust collection cylinder and the cyclone cone; the cyclone cone is provided with a filter channel in communication with the lower opening of the machine body, and is provided with a filter screen assembly for enabling the filter channel to be in communication with the first airflow cavity channel; the cyclone cone is used to enable gas entering the first airflow cavity channel through the air inlet to form a cyclonic airflow when the rotating member rotates, the cyclonic airflow flowing to the lower opening of the machine body through the filter channel. In this way, the cleaning interval of the filter screen assembly is effectively extended, the service life of the filter screen assembly is prolonged, and the cleaning efficiency of the filter screen assembly is improved, and the risk of bacterial growth in the filter screen assembly is reduced.

This utility model relates to a modular ventilator, comprising a main unit, a heating component, and a water tank assembly. The main unit and the heating component are detachably connected via electrical terminals, and the heating component and the water tank assembly are detachably connected via a snap-fit ​​and snap-fit ​​slot unit. Additionally, another snap-fit ​​and snap-fit ​​slot unit is included to prevent the main unit from detaching from the heating component. This utility model is easy to carry and use, especially suitable for outdoor use. It also facilitates user disassembly, cleaning, and maintenance of the water tank, reducing bacterial growth. Furthermore, the modular structure supports functional expansion, allowing users to replace or upgrade components as needed, thus broadening its applicability.

The invention discloses a biochar composite membrane and a selective denitrification method and application thereof, and belongs to the field of sewage treatment.The preparation method comprises the steps that biochar, polystyrene and polydimethylsiloxane are dispersed in an organic solvent to form dispersion liquid, the dispersion liquid is applied to the surface of a substrate, and then curing and drying are conducted to obtain the biochar composite membrane. A biochar composite film is obtained; geobacillus stearothermophilus is inoculated on the surface of the obtained biochar composite membrane, and incubation is carried out under the condition suitable for growth of bacteria until a microbial membrane of the geobacillus stearothermophilus is formed on the surface of the biochar composite membrane; transferring the obtained biochar composite membrane with the microbial membrane formed on the surface into one or more porous suspension balls, and then placing the porous suspension balls on the surface of sewage. The method can be applied to outdoor sewage in-situ efficient selective denitrification, and is more economical, energy-saving, green and environment-friendly.

This utility model belongs to the field of water treatment technology, specifically relating to a water dispenser and equipment for pharmaceutical production using a full membrane process. The water dispenser includes: a water pretreatment system suitable for treating raw water into drinking water, and includes: a filtration module and a sterilization module; the filtration module includes: a first buffer tank suitable for receiving and conveying raw water; a first dosing unit suitable for adding chemicals to the raw water conveyed from the first buffer tank; and a filtration unit equipped with a nanofiltration membrane, suitable for receiving the raw water conveyed from the first buffer tank, filtering it through the nanofiltration membrane, and returning it to the first buffer tank to form a cycle, and suitable for conveying the filtered raw water to the sterilization module after a corresponding cycle time; the water pretreatment system treats the raw water into drinking water, and the water treatment system treats the drinking water into water for injection, and a first loop pipe keeps the water flowing during the treatment process to prevent bacterial growth.

An integrated biofilter for a re-circulating aquaculture system is provided. The biofilter may include a moving bed biofilm reactor (MBBR) with biomedia elements configured to support bacteria growth and nitrification of the wastewater and an MBBR output configured to output biomass generated by the bacteria. The biofilter may also comprise a periphyton biofilter configured to introduce oxygen into the wastewater, and a halophyte biofilter comprising a plurality of plants. The halophyte biofilter configured to capture nutrients in the wastewater to generate edible plant mass.

This invention discloses a pharmaceutical composition containing the natural products osthol and berberine, exhibiting synergistic antibacterial and antifungal effects. The effectiveness of osthol in synergistically enhancing the antibacterial activity of berberine was demonstrated through checkerboard minimum inhibitory concentration (MIC) tests, antifungal activity experiments, and in vitro bacterial growth curves. This invention provides a novel application of the combined use of osthol and berberine in antibacterial and antifungal treatments. This composition belongs to the category of traditional Chinese medicine compound preparations, offering a new treatment strategy for the clinical treatment of bacterial and fungal infectious diseases.

The utility model discloses a sound recording device which comprises a recorder main body and a microphone, the recorder main body is provided with a disinfection mechanism and a blowing mechanism, the recorder main body comprises a machine body, a battery and a protective frame, the battery is installed in the machine body, the protective frame is fixedly installed on the top of the machine body, and the upper end face of the machine body is provided with a positioning groove. The microphone is movably installed in the positioning groove, the disinfection mechanism comprises an atomization nozzle and a water pump, a disinfectant storage cavity is formed in the machine body, the atomization nozzle is fixedly installed on the lower end face of the top of the protection frame, the water pump is connected with a water outlet of the atomization nozzle through a hose, and a water inlet of the water pump is communicated with the disinfectant storage cavity through the hose. The multifunctional microphone has the advantages of automatic disinfection, blow-drying and rotary storage of the microphone, and solves the problems that the traditional microphone is easy to breed bacteria and inconvenient to disinfect.

The present invention pertains to the field of culture media designed for plasmid production. Specifically, it relates to a specialized culture medium for bacterial growth that is optimized to achieve high plasmid yields.

This invention discloses an antimicrobial peptide cAMP-1 derived from the intestinal microorganisms of wild rodents and its applications, belonging to the field of biotechnology. The amino acid sequence of the antimicrobial peptide cAMP-1 is shown in SEQ ID NO:1. The antimicrobial peptide cAMP-1 exhibits highly efficient, rapid, and safe antimicrobial activity against Streptococcus suis type II. It significantly inhibits bacterial growth even at low concentrations, with a minimum inhibitory concentration (MIC) of 16 µg / mL. Time-kinetic kinetics results show that the antimicrobial peptide can kill all Streptococcus suis type II within 30 min and 15 min at concentrations of 2×MIC and 4×MIC, respectively. Furthermore, within several times the effective concentration range, the peptide exhibits almost no hemolytic activity and low cytotoxicity within a safe dosage range, demonstrating its promising application as a novel anti-infective candidate drug.

This invention belongs to the field of biomedical materials and nanotechnology, specifically relating to the synthesis and application of a multifunctional mesoporous nanomaterial. The inventors synthesized a core-shell structured mesoporous nanoparticle using mesoporous silica nanoparticles and dopamine via emulsion epitaxy. The core of the core-shell structured mesoporous nanoparticle is S-nitrosoglutathione supported on mesoporous silica, and the outer shell is pentafluorophenyl chlorophyll supported on mesoporous polydopamine, forming MSN / G@mPDA / F nanoparticles. These nanoparticles rapidly increase in temperature to 45°C under 808 nm laser irradiation. o At temperatures above a certain temperature, S-nitrosoglutathione decomposes to produce nitric oxide. Further irradiation at 750 nm generates a large amount of reactive oxygen species, killing bacteria. This combination of photothermal and photodynamic therapy effectively inhibits bacterial growth. Therefore, this method exhibits excellent antibacterial effects and can play a role in the future treatment of bacterial infections.

This utility model discloses a high-pressure flash tank combined with a gasification scrubbing tower wastewater discharge system, belonging to the field of scrubbing tower technology. It includes a base plate, with a scrubbing tower body mounted on the upper surface of the base plate. The scrubbing tower body contains a scraping mechanism and a moving mechanism. The scraping mechanism includes a mounting frame, with a sliding rod installed inside the mounting frame. This high-pressure flash tank combined with a gasification scrubbing tower wastewater discharge system, through the coordinated action of the moving mechanism and the scraping mechanism, allows the scraper to remove impurities from the bottom of the scrubbing tower, effectively preventing long-term accumulation of impurities. Furthermore, the spring in the scraping mechanism allows the sliding sleeve to flexibly adjust the angle of the connecting rod, ensuring the scraper always remains in close contact with the bottom surface of the scrubbing tower, ensuring more thorough scraping, improving impurity removal efficiency, reducing the possibility of bacterial growth due to impurity accumulation, guaranteeing the purification efficiency of the scrubbing tower, reducing the risk of secondary pollution, and thus ensuring the purification effect.

Provided herein are kits, compositions, systems, and methods for treating a subject with a tumor with kynurenine responsive and degrading bacteria (e.g., such that the bacteria reduces or eliminates the tumor). In certain embodiments, the kynurenine responsive bacteria comprise one or more nucleic acid sequences encoding: i) a kynurenine transcriptional regulator protein, ii) a kynurenine transporter protein, iii) a kynureninase (KynU) protein, and iv) at least one protein important or essential for growth of the bacteria expression of which is linked to a kynurenine responsive promoter (e.g., where the corresponding gene(s) has been deactivated or knocked out in the genome of the bacteria).

The present application relates to a portable multifunctional brush storage system based on voice interaction and AI control. The system directly or indirectly evaluates the bacterial load by integrating optical sensors, and combines multi-dimensional micro-environmental data such as temperature, humidity, and air quality. The AI intelligent control center dynamically generates and executes the optimal disinfection and drying strategy. This makes disinfection and drying no longer a fixed length of "routine", but a precise response according to the actual health needs, thereby more effectively inhibiting bacterial growth at the root, ensuring brush hygiene, and greatly improving the intelligence of the brush. Moreover, users can directly control all functions and obtain status feedback through natural voice commands. This greatly reduces the use threshold and improves the intuitiveness and convenience of operation.

The present application belongs to the field of papermaking industry water treatment and clean production, especially to a white water treatment system suitable for the spraying water of the wire section and press section of a paper machine, which comprises: a clean water pretreatment unit for high-precision filtration of clean water to remove suspended solids and particulate impurities in the water and ensure the cleanliness of the spraying water; a high-pressure liquid supply unit connected with the clean water pretreatment unit for pressurizing the pretreated clean water to ultrahigh pressure and secondary precision filtration to provide a stable high-pressure cleaning water source; a water quality stabilization unit connected with the high-pressure liquid supply unit for adding a compounded agent to the high-pressure spraying water and real-time regulation and control of the water quality to inhibit bacterial growth and scaling corrosion; and a partition spraying unit connected with the high-pressure liquid supply unit for ultrahigh-pressure precision cleaning of the forming wire and press felt of the wire section and press section of the paper machine. The present application provides a high-integration, recyclable, energy-saving and consumption-reducing spraying water white water treatment system.

The invention relates to the technical field of medicine, and discloses an artemisinin external gel composition as well as a preparation method and application thereof, the gel composition comprises 0.1-5 parts of artemisinin, 1-20 parts of a solubilizer, 0.5-15 parts of a gel matrix, 5-30 parts of a penetration enhancer, 0.01-1 part of a stabilizer, 0.01-2 parts of a pH regulator, 0.05-1.5 parts of a preservative, 1-15 parts of a humectant and purified water. According to the technical scheme, a peroxide bridge structure of artemisinin is used for removing active oxygen, the multiple effects of resisting inflammation, resisting oxidation, resisting bacteria, promoting repair and resisting scars are achieved by regulating and controlling channels such as NF-kappa B and TGF-beta, and meanwhile, a gel matrix maintains a moist environment of a wound surface and promotes transdermal absorption of drugs. Experiments prove that the composition can reduce MDA content of wound surfaces, increase SOD activity, inhibit IL-6, TNF-alpha and other inflammatory factors, reduce collagen deposition and inhibit bacterial growth, can effectively improve the pathological process of scalds and burns, and provides a novel multi-mechanism synergistic external composition for clinical treatment.

The invention discloses a method for killing bovine herpesvirus by sodium chloride aerosol. The method comprises the following steps: (1) preparing sodium chloride aerosol of which the average particle size is 800nm and the particle size distribution is between 500nm and 8mu m, in the specific preparation process, respectively introducing a saturated sodium chloride aqueous solution and absolute ethyl alcohol into dry airflow of a spray dryer according to a volume ratio of 1: 1, and drying by the spray dryer to prepare the sodium chloride aerosol; and (2) the prepared sodium chloride aerosol is used as a bovine herpes virus killing agent to kill bovine herpes viruses, and in the virus killing process, the dosage is 10-60 mg, and the killing time is 10-30 s. The sodium chloride aerosol has the advantages that the sodium chloride aerosol has special antivirus efficacy in a specific dosage and time range, a high-concentration sodium chloride solution can dehydrate bacterial cells and destroy cell membrane structures of the bacterial cells through osmotic pressure difference to cause growth inhibition or death of bacteria, and especially 100% of bovine herpes viruses (BHV-1) can be killed in a very short time with a small dosage of sodium chloride aerosol.

The invention belongs to the technical field of heat exchangers, and discloses a plate heat exchanger rapid liquid drainage structure, a plate heat exchanger comprises a plurality of stacked and welded plates and an end plate welded with the outermost plate, a heat exchange flow channel is formed between adjacent plates, corner holes are formed in four corners of each plate, the corner hole in the bottom is located at the lowest position of the plate, and the end plate is connected with the end plate. Flow guide areas are arranged at the edge positions of the plate sheets, and pipe connecting holes in one-to-one correspondence with the corner holes in position and liquid discharging holes lower than the corner hole in the lowest position are formed in the end plates. On one hand, the main body structure of the plate heat exchanger is slightly changed, the heat exchange performance of the plate heat exchanger is not affected, on the other hand, heat exchange medium residues can be effectively reduced, residual liquid is completely discharged, and the problems of corrosion, bacterial colony breeding, frost cracking and the like are avoided.

This invention belongs to the field of biotechnology and discloses a strain of Bacillus amyloliquefaciens ZJ02 that inhibits bacterial growth and reduces ammonia nitrogen. Its accession number is CCTCC NO: M20252399, the accession date is October 30, 2025, and the depositary institution is the China Center for Type Culture Collection, located at Wuhan University, Wuhan, China. ZJ02 exhibits significant antibacterial effects against Escherichia coli and Salmonella, with an inhibition zone size of 18.11 mm against Salmonella (SA) after 24 hours. Compared to other strains, it demonstrates superior ammonia nitrogen degradation under the same conditions, achieving a degradation rate of 76.58%, reaching as high as 87.57% at an initial ammonia nitrogen concentration of 500 mg / L. Furthermore, it possesses excellent ability to reduce ammonia release from animal feces. In ammonia removal tests conducted in pig farm environments, compared to the control group, the NH3 concentration decreased by 60.27% on day 6, significantly outperforming Bacillus subtilis and Bacillus licheniformis. This invention also provides the application of this Bacillus amyloliquefaciens.

The utility model discloses an automatic cleaning laying hen breeding cage, including hencoop, excrement cleaning mechanism, crib cleaning mechanism and control panel, control panel is installed on one side of hencoop, the hencoop is formed by connecting cage body and frame, excrement cleaning mechanism includes collecting tank, screw transmission group, support seat, cleaning box and cleaning roller, and the cleaning roller is connected with the collecting tank. The feeding trough cleaning mechanism comprises a flow guide pipe and a scraping plate. The chicken coop is provided with the excrement cleaning mechanism, the feeding trough cleaning mechanism and the control panel, excrement generated by laying hen breeding can be automatically collected, excrement adhering to the bottom face of the chicken coop can be cleaned, peculiar smells and virus spreading in a breeding house are reduced, meanwhile, residual feed in the feeding trough is cleaned, and the breeding efficiency is improved. Bacteria breeding in the feeding trough is avoided, a good feeding environment is provided for laying hens, and the egg laying yield is increased.

To measure characteristics of a sample, and in particular, to more accurately evaluate optical characteristics of a biological sample containing microorganism particles such as bacteria.SOLUTION: An apparatus comprising an optical instrument (2) for monitoring bacterial growth in a liquid biological sample to which a drug has been administered. The optical instrument 2 comprises a light source 22 that, in use, illuminates the sample along an incident beam axis that intersects at least one of the sample containers, and a light collection arrangement 24 configured to collect light that has been scattered in a forward direction by bacteria in the sample and to direct the collected scattered light to a first photodetector 26, and to prevent unscattered light travelling parallel to the incident beam axis from reaching the first photodetector 26. Based on the intensity of the scattered light received by the first photodetector 26, a representative amount or change in concentration of bacteria present in the sample as a function of time is determined, and a corresponding susceptibility of the bacteria in the sample to the respective drug is determined.SELECTED DRAWING: Figure 2

A novel 10 peptide capable of inhibiting the growth of bacteria that are resistant to existing polymyxin, a pharmaceutical composition comprising the novel 10 peptide, and an application thereof in the treatment or prevention of bacterial infections.