48 results about "Dietary supplementation" patented technology

The present disclosure relates to a formulation for supporting the growth or maintenance of bacteria in the gastrointestinal tract of an animal. Provided is the use of at least one human milk oligosaccharide in combination with pre-biotics and probiotic strains of bacteria for the manufacture of a food composition, pharmaceutical composition, food or dietary supplement, for the selective stimulation of beneficial bacteria in the gastrointestinal tract in context of a disease condition. Also provided is a synbiotic formulation comprising living beneficial bacteria formulated with at least one human milk oligosaccharide in combination with pre-biotics. In particular, synbiotic formulation is used for improving clinical biomarkers in diseases especially Crohn's disease.

The invention belongs to the field of biotechnology and nutritional medicine, relates to a maternal obesity intervention preparation, and particularly relates to a preparation method of a plant embryo fermentation product and application of the plant embryo fermentation product in blocking of trans-generation delivery metabolic diseases. FWG is prepared through a probiotic fermentation technology, obesity, glucose and lipid metabolism disorder and oxidative stress induced by high-fat diet of a parent body can be remarkably improved, and cross-generation transmission of metabolic diseases is blocked by adjusting composition of intestinal flora of the parent body and offspring and a hypothalamic PI3K-Akt signal channel. The invention reveals that maternal FWG intervention passes through a mechanism that a PI3K-Akt pathway is dominated and multiple pathways are coordinated on the transcriptome level for the first time, the HFD-induced offspring hypothalamus metabolism programming abnormality is reversed, and a new central regulation target is provided for cross-generation metabolic disease prevention. The FWG is a wheat processing byproduct, is free of chemical additives, is suitable for long-term dietary supplement, is a natural and safe nutrition intervention scheme, and is suitable for the field of maternal and infant health.

The present invention relates to the field of medicine and of dietary supplements, in particular the technical (i.e. medical-pharmaceutical or food-technology) field of sleep problems and sleep disorders. In particular, the present invention relates to a dosage form, in particular a dietary-supplement dosage form or pharmaceutical dosage form, in particular for oral administration, preferably for promoting or supporting sleep health or sleep behavior or preferably for use in the prophylactic or therapeutic treatment of sleep disorders or dysregulation of the natural day / night rhythm or the circadian rhythm.

This invention relates to the field of biotechnology, and more particularly to a swelling-promoting seahorse oil and its application in the preparation of anti-sarcopenia products. Obtained using a supercritical carbon dioxide extraction process, the swelling-promoting seahorse oil of this invention has been experimentally verified to inhibit muscle degradation, promote muscle cell activation and differentiation, increase muscle mass, and enhance muscle strength and endurance. Furthermore, it exerts its effects through dietary supplementation with no significant adverse reactions, and can be used to prepare anti-sarcopenia related foods, health products, or pharmaceuticals to meet the muscle health maintenance needs of the elderly.

This invention belongs to the field of pharmaceutical technology, specifically relating to an alginate oligosaccharide, its preparation method, and its applications. Using brown algae as raw material, the invention first removes impurities from the algae, then extracts it through subcritical acid water, followed by neutralization, decolorization, heavy metal removal, membrane ultrafiltration / nanofiltration purification, and spray drying to obtain high-purity saturated alginate oligosaccharides with a specific degree of polymerization distribution. These alginate oligosaccharides can increase butyrate production by intestinal flora and exert a laxative effect. The alginate oligosaccharide and its preparation method provided by this invention directly use brown algae as raw material, overcoming the drawbacks of traditional methods that first prepare alginate and then hydrolyze it to prepare alginate oligosaccharides, greatly shortening the process steps and improving production efficiency. The alginate oligosaccharides provided by this invention have high purity and broad application potential in the preparation of intestinal health drugs, health products, or dietary supplements.

It refers to a dietary product for hypoproteic diet suitable for supplementing the diet in patients suffering from chronic kidney disease, hepatic insufficiency and urea cycle disorders. It also refers to the use of the dietary product as supplement of the diet of said patients. The dietary product comprises amino acids, amino acid analogues, and pharmaceutically acceptable excipients.

The present invention relates to the use of riboprine in the maintenance, improvement, or dietary management of gut barrier function. The riboprine may be formulated in an oral composition such as dietary supplement, a food product, a food for special medical purpose (FSMP) or a food for special dietary use (FSDU).

The present invention relates to hydrophobic sorbent compositions suitable for human or animal consumption. In particular, the compositions comprise fine coffee grounds, and may further comprise activated charcoal. Formulated in solid or liquid oral dosage forms, the compositions are useful as a dietary supplement.

The present invention discloses a use of a compound of formula I or a compound of formula II or a pharmaceutically acceptable salt thereof in preparing a medicine, food, beverage or dietary supplement for preventing and / or treating diabetes, obesity and / or complications thereof associated with AMPK activation, wherein R1 is a hydroxyl group or a C 1‑12 Alkoxy, R2 is hydrogen, R3 is hydrogen or C 1‑12 Alkoxy, R4 is hydrogen. The compound of the present invention can significantly activate the in vitro activity of AMPK and promote glucose uptake, and can be used in the preparation of medicines, foods, beverages or dietary supplements for diabetes, obesity and / or its complications related to AMPK activation. #imgabs0#

Methods are provided for treating and diagnosing diseases and disorders associated with retinal degeneration, such as retinitis pigmentosa. Dietary supplementation with specific metabolites and vitamins can prolong vision and provide a neuroprotective effect. In particular, dietary supplementation with a-ketoglutarate, or a derivative thereof, significantly prolongs photoreceptor cell survival and visual function. In addition, dietary supplementation with B vitamins and a ketogenic diet also improves photoreceptor cell survival and delays disease progression in some cases. Additionally, compositions, methods, and kits are provided for diagnosing a subject with retinitis pigmentosa based on expression levels of vitreous biomarkers.

This invention discloses a regulatory dietary supplement containing mulberry leaf γ-aminobutyric acid (GABA) and polyphenols, and its preparation method, belonging to the field of dietary food technology. It consists of the following raw materials in parts by weight: 15-30 parts mulberry leaf extract, 40-60 parts cereal base, 10-20 parts plant protein powder, 5-15 parts dietary fiber, 2-8 parts mineral fortifier, and 1-5 parts natural sweetener; the mulberry leaf extract contains ≥8 mg / g GABA and ≥15 mg / g total polyphenols; the mineral fortifier is potassium salt, with a sodium content ≤120 mg / 100g and a potassium content ≥500 mg / 100g. The preparation method includes: compound enzymatic hydrolysis-ultrasonic synergistic extraction of mulberry leaf extract, low-temperature drying and pulverization of barley grass powder, premixing and masking the flavor of the mineral fortifier and protein powder, and total granulation. This invention utilizes the synergistic effect of GABA and polyphenols on the neurovascular dual pathway, providing dual functions of soothing emotions and assisting in blood pressure regulation. It is also low in sodium and high in potassium, with an excellent taste, making it suitable for daily dietary supplementation and functional meal replacement for people who value a healthy lifestyle and those with special nutritional needs.

The present invention includes a feed, a feed additive, and method of reducing or eliminating pathogenic bacteria in a mammal comprising providing the mammal with a composition comprising a hydrogel and an amount of copper effective to, e.g., reduce or eliminate pathogen shedding in a mammal, wherein the copper comprises between 0.01 to 100 mg / g of the hydrogel.

A subject matter of the invention is a pharmaceutical single dosage form for oral delivery consisting of two capsules, an outer enteric capsule, and an inner capsule, wherein said inner capsule comprises at least one physiologically active peptide agent and wherein said outer capsule contains inner capsule and an organic acid, wherein said outer capsule contains an absorption enhancer which is a carnitine compound in the form of optionally coated pellets. A subject matter of the invention is also use of the pharmaceutical single dosage form as a dietary supplement.

The invention belongs to the technical field of medicines, and particularly relates to alginate oligosaccharide as well as a preparation method and application thereof. The preparation method comprises the following steps: by taking brown algae as a raw material, firstly performing impurity removal treatment on the brown algae, and then performing subcritical acid water extraction, neutralization, decoloration, heavy metal removal, membrane ultrafiltration / nanofiltration refining, spray drying and the like to obtain the high-purity saturated alginate oligosaccharide with specific polymerization degree distribution. The effect of relaxing bowel is achieved. According to the alginate oligosaccharide and the preparation method thereof provided by the invention, the brown algae is directly adopted as the raw material, so that the defect that the alginate oligosaccharide is prepared firstly and then hydrolyzed in the traditional method is overcome, the process steps are greatly shortened, and the production efficiency is improved. The alginate oligosaccharide provided by the invention is high in purity, and has wide application potential in preparation of intestinal health medicines, health care products or dietary supplements.

A core four dietary supplement system comprising at least one collagen system, at least one microdaily EMF system, at least one omega-3 system and at least one prebiotic and probiotic system with acid and heat resistant bacteria, is provided.

Methane production in ruminants can be reduced by improving rumen fermentation efficiency through dietary supplementation with Asparagopsis taxiformis. This disclosure relates to a method for producing A. taxiformis and its use. In a specific form, this disclosure relates to a method for producing tetrasporophytes and gametophytes of A. taxiformis by environmental manipulation.

The invention relates to the technical field of biology, in particular to belly-distending hippocampus oil and application thereof in preparation of sarcopenia-resistant products. The swelling sea horse oil is obtained by adopting a supercritical carbon dioxide extraction process, and experiments prove that the swelling sea horse oil can inhibit muscle degradation, promote muscle cell activation and differentiation and increase muscle weight, muscle strength and endurance; the composition can play a role in a dietary supplement mode, has no obvious adverse reaction, can be used for preparing anti-sarcopenia related food, health care products or medicines, and meets the requirements of old people for muscle health maintenance.

The present disclosure provides a novel supplement composition comprising a 2:1 molar ratio of taurine to malic acid, which can be added to food or beverages, or incorporated as a dietary supplement. The present supplement composition when added to a food, beverage or dietary supplement provides various health benefits, including ergogenic effects of enhanced physical performance, stamina, and recovery, threshold pain reduction, increased power, and increased vasodilation for improved recovery and performance.

The invention discloses a general flavone extraction process and application, and the general flavone extraction process comprises the following steps: taking general flavone-containing plant source powder, adding an extracting solution according to a material-liquid ratio of 1: (10-50), and carrying out ultrasonic treatment for 10-50 minutes at the temperature of 40-80 DEG C to obtain the extracting solution containing general flavone. As an important bioactive substance, the general flavone is an indispensable nutrient for maintaining normal vital activities of a human body. The general flavone shows multielement and remarkable biological activity, plays an important role in resisting oxidation, inflammation, tumors, bacteria and viruses and preventing and improving diseases such as hypertension and hepatic fibrosis, and is an important dietary supplement component for maintaining health. The extraction process is simple, the total flavonoids can be extracted only by utilizing the ethanol aqueous solution and performing simple treatment, and the extracted total flavonoids still maintain good activity through detection.

The present invention discloses a self-adaptive generation system of a diabetes diet plan based on deep learning, including: a collection and storage module, configured to collect and produce data on the dynamic changes of the total calories of patients, and construct a personalized data set for generating a calorie supplement plan according to the basal metabolic rate, occupational consumption, exercise consumption, dietary supplement, and the difference between the waist-to-hip ratio and the mean of fasting blood glucose; a calculation module, which imports the personalized data set into an improved linear regression model and performs data training to obtain the corresponding optimal weight of each data in the data set; an evaluation and feedback module, which automatically calculates the dietary calorie supplement value according to the optimal weight and deviation value of the calculation module by setting up a dual gradient target, generates a personalized diet plan, and timely feedback optimization. The present invention constructs a personalized data set of the total calorie changes of patients, and introduces a deep learning method into the formulation of the patient's diet plan, providing more accurate and scientific dietary guidance for diabetic patients.

The invention relates to a dietary supplement comprising a plant component. The invention is characterized in that the plant component contains a composition of Syzygium cumini and Withania somnifera. Furthermore, according to the invention, the dietary supplement is used for weight reduction.

Disclosed herein are stabilised dihydrofolate formulations intended for use as a dietary supplement. The formulations comprise active dihydrofolate / encapsulated active dihydrofolate, a stabilising agent to prevent degradation, and a carrier medium selected from powders, tablets, or capsules. The innovation provides an effective nutraceutical for oral administration, serving as a potent agent to enhance overall health and support specific bodily functions, especially in individuals with folate deficiency. The formulation remains substantially stable when stored in various temperature conditions (8-50 °C) for an extended period, and methods for preparing these formulations are illustrated.

A gastro-resistant nutraceutical composition is described, comprising a pomace extract (preferably of the Aglianico cultivar), rich in polyphenols, microencapsulated in maltodextrins (MaGPE), preferably in combination with vitamin B2, vitamin A and zinc, and the use thereof to counteract age-related macular degeneration.

The present invention relates to over the counter (OTC) film coated tablet compositions comprising one or more types of vitamins. Specifically, the invention focuses on formulations that include B vitamins, such as thiamine (B1), riboflavin (B2), nicotinamide (B3), pantothenic 5 acid (B5), pyridoxine (B6), biotin (B7), folic acid (B9), and cobalamin (B12). These vitamin- enriched tablets are intended for dietary supplementation to support various bodily functions, including energy metabolism, nervous system health, and the maintenance of healthy skin, hair, and eyes.

A gastro-resistant nutraceutical composition is described, comprising a pomace extract (preferably of the Aglianico cultivar), rich in polyphenols, microencapsulated in maltodextrins (MaGPE), preferably in combination with vitamin B2, vitamin A and zinc, and the use thereof to counteract age-related macular degeneration.

The present disclosure relates to a bioflavonoid composition comprising a bioflavonoid, at least one surfactant with a molecular weight between 300 and 1500 g / mol, and optionally a macromeric compound. The composition exhibits enhanced solubility and bioavailability and may be formulated into various delivery formats, including hard gelatin capsules and nutraceutical food products. The present disclosure also relates to a process for preparing the composition involves mixing the bioflavonoid with optional polysaccharides and suspending agents, followed by the addition of an aqueous surfactant and binder solution. The composition of the present disclosure is suitable for use in dietary supplements or medicaments and may be administered to manage various health conditions or disorders.

A method for preparing a fermented grape marc, which includes the following steps: preparing a grape marc infusion by placing grape marc in contact with water and optionally with a source of sugar chosen among sucrose, glucose syrup, or concentrated grape must; placing the grape marc infusion in contact with a scoby (also called “kombucha microbial consortium”) and optionally with kombucha; fermenting the grape marc infusion for a period ranging from 5 to 35 days, and preferably from 7 to 12 days. Also, fermented grape marc obtainable according to the method, as well as to the use thereof in dietary, nutraceutical, or nutricosmetic supplements, or in dermocosmetic products.

The present invention provides a method for preparing a low-sodium hollow salt capable of dietary supplementation with astaxanthin, comprising the following steps: dissolving Haematococcus pluvialis protein and food-grade polysaccharide in water, adjusting the pH and stirring to obtain a complex solution; adding NaCl and oil to the complex solution, dispersing at high speed and performing high-pressure homogenization treatment to obtain an oil-in-water Pickering emulsion; spray-drying the oil-in-water Pickering emulsion to obtain a low-sodium hollow salt loaded with astaxanthin. The low-sodium hollow salt capable of dietary supplementation with astaxanthin according to the present invention does not contain any surfactants, and can achieve a sodium reduction effect of 30-50%; astaxanthin is encapsulated in the oil phase, solving problems such as poor water solubility and low bioavailability of astaxanthin, and increasing the daily dietary supplementation of astaxanthin; under long-term storage, the low-sodium hollow salt has good astaxanthin retention rate and lipid oxidation stability; it can effectively prevent the oxidation of the grease in fried steak and is beneficial to maintaining its food quality.