3 results about "Arteritis" patented technology

This invention discloses a method and system for predicting severe ischemic events in the nervous system caused by large vessel arteritis based on multimodal deep learning. Belonging to the field of intelligent medical image analysis and clinical risk prediction technology, the method includes: acquiring the patient's magnetic resonance angiography data and clinical information; preprocessing the image data; extracting three-dimensional morphological feature vectors from the point cloud of the blood vessel surface based on a point cloud neural network; extracting blood vessel wall feature vectors from the images based on a three-dimensional convolutional neural network; encoding clinical information to generate clinical feature vectors based on a pre-trained basic model; fusing the above three feature vectors to generate a multimodal fusion feature representation; and outputting an individualized risk score based on this fusion feature through a discrete-time survival analysis model. This invention, through multimodal deep collaborative modeling, achieves automated deep fusion analysis of three-dimensional vascular morphology, blood vessel wall structure, and clinical information, significantly improving prediction accuracy, objectivity, and clinical applicability.

The present disclosure provides compositions and methods for treating or preventing ischemic optic neuropathy with gene therapy vectors that deliver nucleic acid sequences encoding octamer-binding transcription factor 4 (OCT4), sex-determining region (Y)-box 2 (SOX2), and Krüppel-like factor 4 (KLF4). In particular, non-arteritic anterior ischemic optic neuropathy (NAION) can be treated or prevented.

The invention provides an external preparation matched with iontophoresis, and belongs to the technical field of traditional Chinese medicine preparations. The preparation is prepared from ligusticum wallichii, rhizoma wenyujin concisum, semen cassiae and borneol according to specific parts by weight, the preparation method comprises the steps of adding water to decoct, filtering and the like, and the pH value of filtrate is controlled to be 5.5-6.5. During use, the filtrate is soaked in gauze and externally applied to two eyes, ion introduction is matched, an anode electrode is adopted, the current intensity is 0.1-0.5 mA / cm, the duration is 20 min, one time per day and five times per week are adopted, and one month is a course of treatment. The traditional Chinese medicine composition can be used for resisting inflammation, improving early optic atrophy and relieving non-arteritis front ischemic optic neuropathy, can improve the transdermal absorption rate of the medicine and synergistically exert the anti-inflammation and nerve protection effects, and is high in safety, simple and convenient in preparation process and high in clinical value.