The invention discloses a toothache-relieving and inflammation-diminishing tablet. The tablet is prepared from the following components by mass: 20 to 40% of a traditional Chinese medicine concentrate I, 10 to 20% of a traditional Chinese medicine concentrate II, 2 to 8% of ibuprofen, 2 to 8% of erythromycin, 5 to 10% of metronidazole, 5 to 10% of chlorpheniramine, 1 to 5% of borneol, 20 to 40% of glucose powder and 0.2 to 0.6% of magnesium stearate. The traditional Chinese medicine concentrate I is prepared from gartersnake, common monkshood mother root, kusnezoff monkshood root, giant typhonium rhizome, Alpinia chinensis, doubleteeth pubescent angelica root, dandelion, Chinese actinidia root, myrrh, cow-bezoar, bushy sophora, lightyellow sophora root, scorpion and water through extraction and concentration. The traditional Chinese medicine concentrate II is prepared from Veronicastrum sibiricum, safflower, catechu, pseudo-ginseng and water through extraction and concentration. The tablet exerts a substantial effect on toothache caused by gingivitis, periodontitis, carious teeth and other tooth diseases, can rapidly relieve pain and realizes antibiosis and antiphlogosis.