65 results about "Pulpitis" patented technology

Provided is a novel and creative dental tissue regeneration method for regenerating dental tissue after pulpectomy or the enlargement and cleaning of an infected root canal. After pulpectomy or the enlargement and cleaning of an infected root canal, a root canal filler (200) having an extracellular matrix (210) containing the cells (220) enriched for dental pulp stem cells, is inserted into the apical side of the root canal of a target tooth (100). The cells including dental pulp stem cells include at least one of the following: dental pulp SP cells, CD31-negative and CD146-negative cells, CD24-positive cells, CD105-positive cells, and CD150-positive cells. For instance, dental pulp SP cells are CD31− and CD146− negative. Even if pulpitis due to deep caries occurs, appropriate dental pulp regeneration and recovery of dental pulp function are possible.

The invention discloses an intelligent temperature-sensitive sustained-release gel and a preparation method thereof. The intelligent temperature-sensitive sustained-release gel comprises the following components in percentage by weight: 15-25 percent basic remedy, in-situ gel material and water, 2-3 percent of poloxamer 188, 0.5-1 percent of polyethylene glycol-6000, 5-7 percent of ornidazole and 60-70 percent of distilled water. An intelligent temperature-sensitive sustained-release in-situ gel drug-loading system is prepared by combining medicaments with different types of high molecular carrier materials, and is applied to root canal treatment for the first time, so that the defects that the lasting time of the conventional root canal disinfecting and sterilizing effects is short, root canals cannot be fully filled with medicaments under the limitation of dosage form and the like are overcome, the root canal disinfecting operation is simplified, and the double effects of sustained-release long-acting treatment and root canal enclosing are achieved. The one-time success rate of root canal treatment is increased, and the intelligent temperature-sensitive sustained-release gel has an important practical value on the treatment of pulposis, pulpitis and periapical periodontitis and the like.

The invention provides a probiotic chewing gum preparation method. By means of a probiotic embedding technology, survivability of probiotics in chewing gum is kept, and long-time storage is facilitated; by means of the characteristic of long chewing gum chewing time, retention time of probiotics in the oral cavity is prolonged; furthermore, the characteristic that the probiotics can antagonize pathogenic bacteria is utilized to inhibit and kill opportunistic pathogens in the oral cavity; finally, the purposes of preventing and treating oral diseases of ozostomia, pulpitis, periapical periodontitis, gingivitis, periodontitis, acute necrotic ulcerative periodontitis, stomatitis and the like are achieved. In addition, the probiotics can enter gastrointestinal tracts along with saliva to promote host gastrointestinal tract flora health and has recovering and treating effects on symptoms of unacclimatization, anorexia, diarrhea and the like of flora disorder diseases.

The invention relates to a Chinese patent medicine for treating pulpitis, belonging to the technical field of medicaments for treating pulpitis. The Chinese patent medicine is prepared from dried rehmannia root, radix scrophulariae, gypsum, largetrifoliolious bugbane rhizome, manchurian wildginger, pagodatree flower, tree peony bark, cortex lycii radicis, baical skullcap root, Szechuan lovage rhizome, dahurian angelica root, fineleaf schizonepeta herb, divaricate saposhnikovia root, fortune's drynaria rhizome, tribulus terrestris, amur corktree bark, white chrysanthemum and liquoric root, andcan be prepared into various oral formulations according to a conventional pharmaceutical method. The Chinese patent medicine disclosed by the invention has the functions of tonifying qi, invigorating spleen, nourishing stomach, discharging fire, eliminating wind-fire, clearing and activating channels and collaterals, promoting blood circulation, removing blood stasis, strengthening vital qi, eliminating pathogen and regulating immunity and can achieve the purpose of treating pulpitis; and compared with the prior art, the Chinese patent medicine has the prominent substantive characteristics and significance of exact curative effect and convenience in administration.

The invention discloses a traditional Chinese medicine preparation for treating toothache belonging to the field of traditional Chinese medicines. Active ingredients of the traditional Chinese medicine preparation consist of the following raw materials: tikoua fig root, chickweed, bodinier elsholtzia herb, portulaca, acalypha australis, clematis filamentosa dunn, nightshade, walnut root, assam crotalaria leaf, cedar leaves, rhynchosia volubilis, ardisia crispa, frog, sarmentose pepper herb, roxburgh rose root and root of Yunnan larkspur. The traditional Chinese medicine preparation has the effects of diminishing inflammation, alleviating pain, reducing internal heat and detoxifying, has obvious curative effects of treating toothaches such as gingivitis, periodontitis, pyretic toothache, pulpitis and deciduous teeth, is a pure traditional Chinese medicine preparation, is readily available in raw materials of medicinal materials and good in pain-easing effect, does not have a toxic or side effect, has the characteristics of short course of treatment, fast effectiveness, low price and difficult recurrence after administration, and is an ideal traditional Chinese medicine preparation for treating multiple toothaches.

The invention relates to a Chinese medicine preparation for nursing a patient with a toothache and a preparation method of the Chinese medicine preparation. Raw materials for preparing the effective components of the Chinese medicine preparation comprise radix angelicae, climbing nightshade fruits, Japanese plum roots, sunflower disks, cephalanthera falcata, solanum torvum, pratt mountainash root-bark, clinopodium megalanthum, wild ginger, chickweed, alpinia japonica, beautiful phyllodium twig and leaves, apiaries, kusnezoff aconite leaves, humifuse euphorbia herbs and capparis acutifolia. The Chinese medicine preparation is pure, is prepared by utilizing a modern advanced medicine preparing technology, has the effects of clearing away heat and toxic materials, achieving sterilization, diminishing inflammation, expelling wind-evil and achieving detumescence, has a good treatment effect on decayed teeth, pulpitis, periodontitis, the acute pericoronitis of wisdom teeth and the toothache caused by the ache of the whole body, is safe and free of toxic and side effects, and can achieve the effect of treating the primary and the secondary aspects at the same time of the toothache.

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds—Free-B-Ring flavonoids and flavans—for use in the prevention and treatment of diseases and conditions associated with mouth, gums and teeth. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic activity and reduces cytokine production at the mRNA level in normal, aged and damaged periodontal cells and tissues. This invention further provides a method for the prevention and treatment of diseases and conditions of the mouth, gums and teeth. The method for preventing and treating diseases and conditions of the mouth, teeth and gums is comprised of administering to a host in need thereof a therapeutically effective amount of a composition comprising a mixture of Free-B-Ring flavonoids and flavans synthesized and / or isolated from a single plant or multiple plants, preferably in the Scutellaria, Oroxylum, Acacia or Uncaria genus of plants and pharmaceutically and / or cosmetically acceptable carriers. Finally the present invention provides a method for the prevention and treatment of diseases and conditions of the mouth, teeth or gums, including but not limited to periodontal diseases, such as gingivitis, periodontitis, pulpitis, periodontal conditions caused by the physical implantation of oral dentures, trauma, injuries, bruxism, neoplastic and other degenerative processes; material alba, pellicles, dental plagues, calculus, and stains. Use of the composition described herein also affords the benefit of maintaining optimum saliva production and pH, minimizing bacterial growth, reducing the formation of pellicles and plague, inhibiting tooth decalcification and tooth caries (decay), promoting remineralization, which yields healthy gums, whitening teeth, maintaining healthy oral hygiene and reducing oral malodor (halitosis).

A Chinese medicine for treating tooth-ache and pulpitis and fixating teeth is prepared from 18 Chinese-medicinal materials including Chinese angelica root, prepared rehmarria root, coptis root, liquorice root, etc.

The invention relates to a dental composition capable of fast eliminating inflammation and relieving pain and a preparing method of the dental composition. The dental composition mainly consists of clove, pepper, borneol, mint, castor bean and 2-methyl-5-nitroimidazole-1-ethanol according to a certain weight part ratio through processing and preparation. The dental composition has the obvious curative effects on dental diseases such as opsigenes pain, periodontitis, pulpitis, gingival pain and swelling, tooth decay and wind-fire toothache, the curative effectiveness is as high s 100 percent, the cure rate is averagely more than 95 percent, the effect taking is fast, the side effect is small, the varieties of used raw medicine are few, and the cost is reduced.

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds --Free-B-Ring flavonoids and flavans-- for use in the prevention and treatment of diseases and conditions associated with mouth, gums and teeth. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic activity and reduces cytokine production at the mRNA level in normal, aged and damaged periodontal cells and tissues. This invention further provides a method for the prevention and treatment of diseases and conditions of the mouth, gums and teeth. The method for preventing and treating diseases and conditions of the mouth, teeth and gums is comprised of administering to a host in need thereof a therapeutically effective amount of a composition comprising a mixture of Free-B-Ring flavonoids and flavans synthesized and / or isolated from a single plant or multiple plants, preferably in the Scutellaria, Oroxylum, Acacia or Uncaria genus of plants and pharmaceutically and / or cosmetically acceptable carriers. Finally the present invention provides a method for the prevention and treatment of diseases and conditions of the mouth, teeth or gums, including but not limited to periodontal diseases, such as gingivitis, periodontitis, pulpitis, periodontal conditions caused by the physical implantation of oral dentures, trauma, injuries, bruxism, neoplastic and other degenerative processes; material alba, pellicles, dental plagues, calculus, and stains. Use of the composition described herein also affords the benefit of maintaining optimum saliva production and pH, minimizing bacterial growth, reducing the formation of pellicles and plague, inhibiting tooth decalcification and tooth caries (decay), promoting remineralization, which yields healthy gums, whitening teeth, maintaining healthy oral hygiene and reducing oral malodour (halitosis).

The invention provides a negative pressure device attached to hard dental tissues. The negative pressure device attached to the hard dental tissues is used for clinically treating odontogenic noninfectious diseases (such as adamantoblastoma and keratocyst) and odontogenic infectious diseases (such as pulpitis, periapical periodontitis, periapical abscess and periapical cyst) and comprises a closing component, a negative pressure machine, a negative pressure measurer, a liquid recoverer and a medicine holder. The negative pressure device, which is a dental negative pressure drainage device, is made of medical polymer materials and metal materials and is small in size and free from obvious foreign matter sense, the closing component can be fixed to the hard dental tissues, and a local negative pressure state is kept through the negative pressure machine, the negative pressure measurer and a negative pressure control valve, so that symptoms such as tissue absorption and tissue pain caused by positive pressure are decreased, and ossification generated by negative pressure is improved; exudation in the dental pulp cavity and the periapical part is drained to be sucked out, secondary pollution to oral microorganisms is avoided, infection risk is reduced, treatment period is shortened greatly and clinical efficacy of related odontogenic disease treatment is improved.

The Chinese medicine for treating toothache is prepared with drynaria rhizome, puncture vine, rehmannia root and prepared rhizome of rehmannia in certain proportion. The preparation process includes crushing drynaria rhizome, puncture vine and rehmannia root into powder, pulverizing prepared rhizome of rehmannia, mixing, and bagging in 25-35 g each. The Chinese medicine has the functions of cooling, detoxicating, diminishing inflammation and relieving pain. It has excellent curative effect on gingivitis, peridentitis, pulpitis and other toothache diseases.

The invention discloses a traditional Chinese medicine preparation for treating diseases such as pathogenic toxin marrow invasion-type acute alveolar bone osteomyelitis. The traditional Chinese medicine preparation is prepared from dried rhizome of rehmannia, rehmannia glutinosa, radix scrophulariae, honeysuckle, rhizome drynariae, nidus vespae, fructus, liaodiaozhu (Chinese character), radix angelicae, asarum, mint, borneol, malt sugar juice, or proper glutinous rice liquor binder, Chinese medicinal herbs and package materials to be prepared into herbal tea, or oral liquid or granular preparation. The traditional Chinese medicine preparation is mainly used for preventing and treating the diseases caused by oral evil poison invasion-type acute alveolar bone osteomyelitis, pulpitis, alveolar bone abscess, alveolar bone tissue periphery infection, pulpitis of alveolar bone, teeth moth, caused pain and the like. The traditional Chinese medicine preparation has the advantages and beneficial effects of being abundant in drugs, easy to prepare, convenient to take, strong in guidance force, fast to become effective, good in curative effect, free of poison and side effects, high in total curative rate in clinical application and the like, and has an innovation on medical tea culture research of the diseases such as oral alveolar bone osteomyelitis.

A Chinese medicine in the form of dropping pill for treating toothache, decayed tooth, pulpitis, gingivitis, etc is prepared from 8 Chinese-medicinal materials including subprostrate sophora root, phellodendron bark, trichosanthes root, dahurian angelica root, etc. Its advantages are high curative effect, and no toxic by-effect.

The invention discloses a tooth desensitizer penetrating into closed canaliculi dentales and preventing biomembrane from formation. The tooth desensitizer comprises pegylation protein (lysozyme, bovine serum albumin, insulin and alpha-lactalbumin), tris(2-carboxyethyl)phosphine hydrochloride, calcium chloride and a pH regulation agent. The tooth desensitizer disclosed by the invention can penetrate to be coated in small holes of teeth by methods of soaking, film coating and the like; and under saliva environment, remineralization of inner parts of the canaliculi dentales can be induced, so that the tooth desensitizer can penetrate into closed small holes. In addition, after forming the coating, the desensitizer has excellent anti-pollution capacity, can prevent biomembranes from formationon dentin, and can prevent diseases of odontophlegmon and the like from generation. The desensitizer disclosed by the invention is non-toxic and non-irritating, and has great prospects in clinical application.

The invention discloses a medicine for treating odontalgia, which is prepared from the following active pharmaceutical ingredients: 20-30g of honeysuckle flower, 20-30g of Paris polyphylla, 20-30g of Fructus Forsythiae, 10-20g of Baikal skullcap root, 10-20g of moutan bark, 10-20g of herba schizonepetae, 5-15g of rhizoma anemarrhenae and 5-15g of Chinese wolfberry. The preparation method comprises the following steps: putting the raw materials on a stir-frying pot, adding water to immerse the raw materials, soaking for 1 hour, boiling with soft fire, continuing decocting for 20-30 minutes, and filtering to remove decoction dregs, thereby obtaining the medicine for treating odontalgia. The medicine for treating odontalgia is preferably taken warmly, and taken orally once a day. The medicine disclosed by the invention can be used for treating odontalgia caused by pulpitis, periodontitis, periodontal disease and the like. The application to 52 patients proves that the medicine for treating odontalgia cures 47 patients, has obvious effect on 2 patients, takes effect on 1 patient, and has no effect on 2 patients. Thus, the effective rate is 90.4%, and the total effective rate is 96.2%.

The invention relates to a medicament for treating oralcavity diseases, wherein the medicament uses Hmong medicinal plants as raw materials and comprises 1.5 to 3 parts of Duchesnea indica, 1 to 2 parts of Datura metel L., 2 to 4 parts of Aletris spicata, 3 to 5 parts of Houttuynia cordata Thunb (usually called heartleaf houttuynia herb), and 1 to 2 parts of Calamus rhabdocladus Burret. The Miao medicine is suitable for local treatment of periodontal disease, dental caries, pulpitis, gingivitis, pericoronitis, periapical periodontitis, oral mucosa ulcer, angular cheilitis, glossitis and oral mucositis caused by radiotherapy and chemotherapy, has advantages of definite efficacy, no toxicity and no stimulation, and can quickly stop toothache and completely resolve three major problems of unbearable pain, refractory ulcer and repeated attack of the oral mucosa ulcer.

The invention relates to a chewing gum containing herba ecliptae and a preparation method thereof. The chewing gum is prepared from herba ecliptae extract, clove, herba menthae extract, a gum base, a sweetener and essence. The preparation method comprises the following steps: crushing all the components; uniformly mixing; pouring and molding; cooling. The pharmaceutical effective component herba ecliptae extract in the chewing gum has a remarkable synergistic effect when being combined with the clove and the herba menthae extract; an in-vitro antibacterial experiment result shows that the chewing gum has remarkable inhibition effects on main bacteria including streptococcus mutans and actinomyces viscosus which cause decayed teeth in oral cavities, so that the chewing gum can be used for preventing and treating oral cavity diseases caused by the bacteria, such as the decayed teeth, pulpitis, periapical periodontitis, gingivitis and the like.

The invention discloses a Chinese patent drug for treating toothache, which contains the following material medicines by weight proportions: 3-10 portions of beam root, 25-35 portions of gypsum, 5-15 portions of corn mint, and 5-15 portions of lesser galangal. During production, the gypsum is grinded into powder, then the beam root, the corn mint, and the lesser galangal are mixed and grinded into powder, and then the powders are mixed evenly for making pulvis, then the pulvis is enclosed into a filter paper bag. The medicament disclosed by the invention is lesser but better, can treat the symptoms and root of the disease simultaneously, is applicable for the sufferers with gingivitis, pulpitis, parodontitis, pericoronitis, tip pericoronitis, and other dental disease. The cure rate reaches 93.2 percent, and the total effectivity reaches 98.4 percent. The medicine directly acts on the afflicted part of toothache by external rinse in mouth, the cure on common sufferer can take effect exactly on the same day, the sufferer can be healed within two weeks, dispensing with hospitalization. The usage of the medicine is safer without harmful side effect. So that the patient suffers less pain, with less cost, and can accept the Chinese patent drug easier.

Provided is a novel and creative dental tissue regeneration method for regenerating dental tissue after pulpectomy or the enlargement and cleaning of an infected root canal. After pulpectomy or the enlargement and cleaning of an infected root canal, a root canal filler (200) having an extracellular matrix (210) containing the cells (220) enriched for dental pulp stem cells, is inserted into the apical side of the root canal of a target tooth (100). The cells including dental pulp stem cells include at least one of the following: dental pulp SP cells, CD31-negative and CD146-negative cells, CD24-positive cells, CD105-positive cells, and CD150-positive cells. For instance, dental pulp SP cells are CD31− and CD146− negative. Even if pulpitis due to deep caries occurs, appropriate dental pulp regeneration and recovery of dental pulp function are possible.

The invention discloses a health care toothpaste prepared from multiple traditional Chinese medicines and used for treating oral diseases. The health care toothpaste is prepared from ginseng, gynostemma pentaphyllum, panax notoginseng, alum, cleistocalyx operculatus, tuckahoe, rhizome bletillae, angelica sinensis, foeniculum vulgare and mint. The health care toothpaste has effects of clearing away heat and toxic materials, diminishing inflammation and killing parasites, relieving swelling and pain, stopping bleeding and promoting granulation and the like, is remarkable in effect on treating oral diseases such as oral ulcer, tooth swelling, alveolar abscess, gingivitis, periodontitis, pulpitis and the like, has the effective rate of 100%, can achieve the effects of resolving the current problems and eliminating the root causes, can achieve the aim that diseases do not easily recur after healing, and can particularly play a role in stopping pain for toothache; if being used for a long term, the health care toothpaste not only can play good repair and health care effects on the cell tissue of the oral cavity, but also can be used for solving and preventing gum bleed, increasing the nutrition of gum, improving the periodontium and achieving the effects on resisting to fungi and inhibiting bacterial growth; when externally applied, the health care toothpaste also has a certain curative effect on injuries such as scalds and the like; and the health care toothpaste is favorably praised by all people after being applied clinically for many years.

The invention relates to the technical field of biology, in particular to a human JNK1 (c-Jun N-terminal kinase) gene targeting small interfering RNA (ribonucleic acid) and application thereof. The small interfering RNA comprises a sense strand and an anti-sense strand, a nucleotide sequence of the sense strand is as shown in SEQ ID NO:2, and a nucleotide sequence of the anti-sense strand is as shown in SEQ ID NO:3. The sequences of the small interfering RNA are not publically reported yet, interference after transcription of the JNK1 gene can be realized to reduce expression of p-JNK in inflamed dental pulp stem cells, apoptosis of the dental pulp stem cells can be specifically reduced, odontoblast differentiation of the dental pulp stem cells is promoted, and a novel treatment scheme is provided for pulpitis.

The invention discloses traditional Chinese medicine oral liquid for treating toothaches. The traditional Chinese medicine oral liquid is prepared from the following active pharmaceutical ingredients in parts by weight: 10-15 parts of bamboo leaves, 25-35 parts of realgar, 7-12 parts of baical skullcap root, 10-20 parts of oyster shell, 10-15 parts of cassia bark, 10-15 parts of common anemarrhena rhizome, 7-13 parts of Indian bread, 15-25 parts of honeysuckle, 6-12 parts of seville orange flower, 10-20 parts of paniculate swallowwort root, 3-8 parts of radix astragali, 6-12 parts of Chinese mahonia, 6-12 parts of Chinese lovage and 6-12 parts of fried great burdock achene. The traditional Chinese medicine decoction can be used for treating toothaches including toothaches caused by pulpitis, peripheral inflammation of tooth apexes, periodontal diseases and the like. The traditional Chinese medicine oral liquid is orally taken twice a day, about 10ml each time. Seven days is a course of treatment. Generally, the aches are obviously alleviated after a course of treatment. The aches basically disappear and redness and swelling of the gum disappear and are cured after two courses of treatment. After curing, the traditional Chinese medicine oral liquid can be continuously taken for one to three courses of treatment to consolidate the curative effects.

The invention discloses application of non-woven fabric in preparing a drug for treating oral diseases and a preparation. The non-woven fabric is made into a patch, thus, the non-woven fabric can cling to a focus in an oral cavity for a long term to adsorb anti-bacterial factors and antihemorrhagic factors of spittle and gingival crevicular fluid in the oral cavity, and under the condition that the drug is not used, inflammations of the oral cavity are improved. Meanwhile, the patch made of the non-woven fabric is attached to the focus of a toothache, and sanies in a medullary cavity can be drained out through a capillary action to achieve an effect of stopping pains. The non-woven fabric has a very good action of stopping intense pains caused by subjective (acute inflammation) toothache, touched toothache (chronic inflammation) and pulpitis. By using the non-woven fabric as a drug carrier, the drug can more rapidly and directly reach the focus; the utilization ratio of the drug is high; the drug also can be slowly released, thus, the goal of long-term treatment is achieved.

The invention belongs to the technical field of a medical and dental formula product, and especially relates to a paste for treating pulpitis and an application thereof. The paste is composed of glycerin iodohydrin, iodoform, glutaraldehyde, an oily substrate, and calcium hydrate, wherein the volume ratio of glycerin iodohydrin to iodoform to glutaraldehyde to the oily substrate is 3-4:1-2:1-2:3-4, the proportion of the oily substrate to calcium hydrate is ml:g being 1:4-6, and the above components are mixed and a mixture is blended to obtain the paste for treating pulpitis. The paste for treating pulpitis has active effect for preservation and treatment of vital pulp-teeth, and avoids nerve injury after dental pulp exposing, denervation, and root canal therapy, so that pain for treatmentcan be alleviated, dental pulp tissue inflammation diminishing is promoted, and restoration and regeneration are realized.

The invention relates to a traditional Chinese medicine preparation for nursing a patient suffering from toothache and a preparation method. The effective ingredients of the traditional Chinese medicine preparation comprise radix angelicae dahuricae, fruits of bittersweet, roots of Japanese plum, helianthus annuus L., cephalanthera falcate, roots of water nightshade, pratt mountainash root-bark, herb of bigflower clinopodium, forbes wildginger herbs, chickweed, rhizome of Japanese galangal, beautiful phyllodium twigs and leaves, nidus vespae, folium aconiti kusnezoffii, herba euphorbiae humifusae and roots of Hongkong caper. The traditional Chinese medicine preparation is a pure traditional Chinese medicine preparation and prepared through a modern advanced medical pharmaceutical technology, has the effects of clearing away heat and toxic materials, sterilizing and diminish inflammation and expelling wind to reduce swelling, has a good treatment effect on toothache caused by decayed teeth, pulpitis, periodontitis, acute dens sapiens and systemic pain, is safe and free of toxic or side effect and can achieve the effect of treating both symptoms and root causes of toothache.

The invention relates to a Chinese medicine preparation for nursing a patient with a toothache and a preparation method of the Chinese medicine preparation. Raw materials for preparing the effective components of the Chinese medicine preparation comprise radix angelicae, climbing nightshade fruits, Japanese plum roots, sunflower disks, cephalanthera falcata, solanum torvum, pratt mountainash root-bark, clinopodium megalanthum, wild ginger, chickweed, alpinia japonica, beautiful phyllodium twig and leaves, apiaries, kusnezoff aconite leaves, humifuse euphorbia herbs and capparis acutifolia. The Chinese medicine preparation is pure, is prepared by utilizing a modern advanced medicine preparing technology, has the effects of clearing away heat and toxic materials, achieving sterilization, diminishing inflammation, expelling wind-evil and achieving detumescence, has a good treatment effect on decayed teeth, pulpitis, periodontitis, the acute pericoronitis of wisdom teeth and the toothache caused by the ache of the whole body, is safe and free of toxic and side effects, and can achieve the effect of treating the primary and the secondary aspects at the same time of the toothache.

The invention provides a traditional Chinese medicine formula preparation for treating toothache, which comprises the following raw materials in parts by weight: 8-12 parts of radices sileris, 8-12 parts of radix angelicae, 20-30 parts of borneol, 20-30 parts of asarum, 20-30 parts of radix aconiti kusenzoffii, 20-30 parts of radix aconite, 20-30 parts of raw rhubarb, 6-10 parts of venenum bufonis, 35-45 parts of camphor, 10-20 parts of clove, 8-12 parts of fructus piperis longi, 6-12 parts of coptis chinensis, 15-25 parts of rhizoma drynariae, 15-25 parts of loose knot, 20-30 parts of radix achyranthis bidentatae, 20-30 parts of oroxylum indicum, 8-12 parts of realgar and 2,000 ml ethyl alcohol with the concentration of 95%. According to the traditional Chinese medicine formula preparation for treating toothache and a preparation method thereof, provided by the invention, the traditional Chinese medicine preparation has the effects of diminishing inflammation, easing pain, reducing internal fire and detoxifying, and has a very good effect on treatment of toothache symptoms such as periodontitis, tooth decay, pulpitis and deciduous teeth.

The invention provides a clinical treatment for odontogenic non-infectious diseases (such as ameloblastoma, keratocyst, etc.) and odontogenic infectious diseases (such as pulpitis, periapical periodontitis, periapical abscess, periapical cyst, etc.) attached to the tooth hard tissue negative pressure drainage device, including sealing parts, negative pressure machine, negative pressure measuring device, liquid recovery device, drug placer; the dental negative pressure drainage device is made of medical polymer Made of high-quality materials and metal materials, it is small in size and has no obvious foreign body sensation. It can fix the sealing part on the hard tissue of the tooth. Through the negative pressure machine, negative pressure measuring device and negative pressure control valve, the local negative pressure state can be maintained to reduce the Symptoms such as tissue absorption and pain caused by positive pressure can improve the osteogenesis effect caused by negative pressure, and at the same time drain and suck out the exudate fluid in the pulp cavity and periapical parts, avoiding secondary contamination of oral microorganisms, reducing the chance of infection, and extremely Greatly shorten the treatment cycle and improve the clinical efficacy of the treatment of odontogenic related diseases.