65 results about "Pulpitis" patented technology

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds—Free-B-Ring flavonoids and flavans—for use in the prevention and treatment of diseases and conditions associated with mouth, gums and teeth. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic activity and reduces cytokine production at the mRNA level in normal, aged and damaged periodontal cells and tissues. This invention further provides a method for the prevention and treatment of diseases and conditions of the mouth, gums and teeth. The method for preventing and treating diseases and conditions of the mouth, teeth and gums is comprised of administering to a host in need thereof a therapeutically effective amount of a composition comprising a mixture of Free-B-Ring flavonoids and flavans synthesized and / or isolated from a single plant or multiple plants, preferably in the Scutellaria, Oroxylum, Acacia or Uncaria genus of plants and pharmaceutically and / or cosmetically acceptable carriers. Finally the present invention provides a method for the prevention and treatment of diseases and conditions of the mouth, teeth or gums, including but not limited to periodontal diseases, such as gingivitis, periodontitis, pulpitis, periodontal conditions caused by the physical implantation of oral dentures, trauma, injuries, bruxism, neoplastic and other degenerative processes; material alba, pellicles, dental plagues, calculus, and stains. Use of the composition described herein also affords the benefit of maintaining optimum saliva production and pH, minimizing bacterial growth, reducing the formation of pellicles and plague, inhibiting tooth decalcification and tooth caries (decay), promoting remineralization, which yields healthy gums, whitening teeth, maintaining healthy oral hygiene and reducing oral malodor (halitosis).

Provided is a novel and creative dental tissue regeneration method for regenerating dental tissue after pulpectomy or the enlargement and cleaning of an infected root canal. After pulpectomy or the enlargement and cleaning of an infected root canal, a root canal filler (200) having an extracellular matrix (210) containing the cells (220) enriched for dental pulp stem cells, is inserted into the apical side of the root canal of a target tooth (100). The cells including dental pulp stem cells include at least one of the following: dental pulp SP cells, CD31-negative and CD146-negative cells, CD24-positive cells, CD105-positive cells, and CD150-positive cells. For instance, dental pulp SP cells are CD31− and CD146− negative. Even if pulpitis due to deep caries occurs, appropriate dental pulp regeneration and recovery of dental pulp function are possible.

The invention relates to the technical field of biology, in particular to a human JNK1 (c-Jun N-terminal kinase) gene targeting small interfering RNA (ribonucleic acid) and application thereof. The small interfering RNA comprises a sense strand and an anti-sense strand, a nucleotide sequence of the sense strand is as shown in SEQ ID NO:2, and a nucleotide sequence of the anti-sense strand is as shown in SEQ ID NO:3. The sequences of the small interfering RNA are not publically reported yet, interference after transcription of the JNK1 gene can be realized to reduce expression of p-JNK in inflamed dental pulp stem cells, apoptosis of the dental pulp stem cells can be specifically reduced, odontoblast differentiation of the dental pulp stem cells is promoted, and a novel treatment scheme is provided for pulpitis.

The invention relates to a Chinese medicine preparation for nursing a patient with a toothache and a preparation method of the Chinese medicine preparation. Raw materials for preparing the effective components of the Chinese medicine preparation comprise radix angelicae, climbing nightshade fruits, Japanese plum roots, sunflower disks, cephalanthera falcata, solanum torvum, pratt mountainash root-bark, clinopodium megalanthum, wild ginger, chickweed, alpinia japonica, beautiful phyllodium twig and leaves, apiaries, kusnezoff aconite leaves, humifuse euphorbia herbs and capparis acutifolia. The Chinese medicine preparation is pure, is prepared by utilizing a modern advanced medicine preparing technology, has the effects of clearing away heat and toxic materials, achieving sterilization, diminishing inflammation, expelling wind-evil and achieving detumescence, has a good treatment effect on decayed teeth, pulpitis, periodontitis, the acute pericoronitis of wisdom teeth and the toothache caused by the ache of the whole body, is safe and free of toxic and side effects, and can achieve the effect of treating the primary and the secondary aspects at the same time of the toothache.

The invention relates to a Chinese patent medicine for treating pulpitis, belonging to the technical field of medicaments for treating pulpitis. The Chinese patent medicine is prepared from dried rehmannia root, radix scrophulariae, gypsum, largetrifoliolious bugbane rhizome, manchurian wildginger, pagodatree flower, tree peony bark, cortex lycii radicis, baical skullcap root, Szechuan lovage rhizome, dahurian angelica root, fineleaf schizonepeta herb, divaricate saposhnikovia root, fortune's drynaria rhizome, tribulus terrestris, amur corktree bark, white chrysanthemum and liquoric root, and can be prepared into various oral formulations according to a conventional pharmaceutical method. The Chinese patent medicine disclosed by the invention has the functions of tonifying qi, invigorating spleen, nourishing stomach, discharging fire, eliminating wind-fire, clearing and activating channels and collaterals, promoting blood circulation, removing blood stasis, strengthening vital qi, eliminating pathogen and regulating immunity and can achieve the purpose of treating pulpitis; and compared with the prior art, the Chinese patent medicine has the prominent substantive characteristics and significance of exact curative effect and convenience in administration.

The invention provides a clinical treatment for odontogenic non-infectious diseases (such as ameloblastoma, keratocyst, etc.) and odontogenic infectious diseases (such as pulpitis, periapical periodontitis, periapical abscess, periapical cyst, etc.) attached to the tooth hard tissue negative pressure drainage device, including sealing parts, negative pressure machine, negative pressure measuring device, liquid recovery device, drug placer; the dental negative pressure drainage device is made of medical polymer Made of high-quality materials and metal materials, it is small in size and has no obvious foreign body sensation. It can fix the sealing part on the hard tissue of the tooth. Through the negative pressure machine, negative pressure measuring device and negative pressure control valve, the local negative pressure state can be maintained to reduce the Symptoms such as tissue absorption and pain caused by positive pressure can improve the osteogenesis effect caused by negative pressure, and at the same time drain and suck out the exudate fluid in the pulp cavity and periapical parts, avoiding secondary contamination of oral microorganisms, reducing the chance of infection, and extremely Greatly shorten the treatment cycle and improve the clinical efficacy of the treatment of odontogenic related diseases.