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209 results about "Forsythia suspensa" patented technology

Forsythia suspensa (Chinese: 连翘; pinyin: liánqiào, weeping forsythia or golden-bell) is a species of flowering plant in the family native to Asia. It is one of the 50 fundamental herbs used in traditional Chinese medicine. It contains the lignans Pinoresinol and phillyrin.

Biological agent, preparation method thereof and application of biological agent in preparation of products for inhibiting escherichia coli

The invention belongs to the field of microorganisms and fermentation, and relates to a biological preparation, a preparation method thereof and application of the biological preparation in preparation of products for inhibiting escherichia coli. And the biological agent is a co-fermentation product of fructus forsythiae and bacillus amyloliquefaciens (Bacillus amyloliquefaciens). The biological preparation provided by the invention can obviously improve the secretion of IFN-alpha in a mouse body, reduce the production of IL-1beta, IL-6 and TNF-alpha, increase the proportion of CD3 + CD4 + and CD3 + CD8 + T cells, and improve the expression of ZO-1 and Occludin in duodenum and jejunum. Compared with single use of fructus forsythiae and bacillus amyloliquefaciens, the biological preparation shows a stronger synergistic effect, can effectively prevent and inhibit escherichia coli infection, and is not easy to generate drug resistance. The preparation method is simple, raw materials are easy to obtain, and the feed additive is suitable for developing antibacterial drugs and feed additives.
Owner:TONGLIAO ACADEMY OF AGRICULTURE & ANIMAL HUSBANDRY SCIENCE

Anti-aging composition and application thereof in skin care field

The invention relates to the technical field of skin care products, in particular to an anti-aging composition and application thereof in the field of skin care. The anti-aging composition provided by the invention comprises the following components in parts by mass: 0.01-2 parts of ergothioneine, 5-30 parts of a plant extract and 2-5 parts of a second anti-oxidation component, the second anti-oxidation component is any one of asiaticoside, resveratrol, glabridin, glutathione and vitriol, and the second anti-oxidation component is any one of asiaticoside, resveratrol, glabridin, glutathione and vitriol. The plant extract is any one or more of a licorice root (GLYCYRRHIZA URALENSIS) extract, a fructus forsythiae (FORSYTHIA SUSPENSA) extract, a viola mandshurica flower extract, a ligusticum wallichii (LIGUSTICUM CHUANXIONG) extract and a cynanchum atratum (CYNANCHUM ATRATUM) extract, and the plant extract is one or more of a radix glycyrrhizae (GLYCYRRHIZA URALENSIS) extract, a fructus forsythiae (FORSYTHIA SUSPENSA) extract, a viola mandshurica (VIOLA MANDSHURICA) flower extract, a ligusticum wallichii (LIGUSTICUM CHUANXIONG) According to the anti-aging composition, the ergothioneine and the second antioxidant are compounded, and then the effective plant extract is added, so that all the components of the anti-aging composition can reduce the overall raw material cost of a skin care product through a good synergistic effect, and the good anti-aging effect of the skin care product is kept.
Owner:CHENGDU QIANTANG BIOMEDICAL TECHNOLOGY CO LTD

Traditional Chinese medicine composition for treating cold as well as preparation method and application thereof

PendingCN120078872AAntibacterial agentsNervous disorderBelamcanda chinensisBistorta officinalis
The invention belongs to the technical field of traditional Chinese medicine research, and particularly relates to a traditional Chinese medicine composition for treating cold and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 7-11 parts of cistanche, 10-14 parts of dried ginger, 7-11 parts of pogostemon cablin, 13-17 parts of pericarpium citri reticulatae, 10-14 parts of polygonum cuspidatum, 7-11 parts of bistort rhizome, 8-12 parts of fructus forsythiae, 28-32 parts of honeysuckle, 10-14 parts of radix bupleuri, 10-14 parts of blackberry lily, 8-12 parts of notopterygium root, 7-11 parts of radix angelicae pubescentis, 7-11 parts of divaricate saposhnikovia root, 7-11 parts of schizonepeta, 7-11 parts of radix angelicae, 10-14 parts of fingered citron, 7-11 parts of perilla stem, 13-17 parts of artemisia apiacea and 10-14 parts of folium mori. The traditional Chinese medicine composition has a better curative effect on cold-dampness cold.
Owner:新疆医科大学第四附属医院

Anti-allergy soothing composition aiming at sensitive skin and preparation method of anti-allergy soothing composition

The invention discloses an anti-allergy soothing composition for sensitive skin and a preparation method of the anti-allergy soothing composition. The anti-allergy soothing composition is prepared from the following components: a PIPER METHYSTICUM leaf / root / stem extract and a FORSYTHIA SUSPENSA fruit extract, wherein the PIPER METHYSTICUM leaf / root / stem extract and the FORSYTHIA SUSPENSA fruit extract are used as raw materials. Raw materials such as kava pepper and fructus forsythiae are preferably selected, lactobacillus is adopted for fermentation, and then purification and refinement are performed. The compound can be used as an active ingredient in a cosmetic formula. Tests prove that the anti-allergy soothing composition has a good sensitive skin care and repair effect.
Owner:广州嘉瑞新材料有限公司

Ventilation system and method for forsythia suspensa planting and cultivation room

The invention discloses a ventilation system and method for a forsythia suspensa planting room, and relates to the technical field of plant cultivation ventilation, the ventilation system comprises a greenhouse support frame, and further comprises a blast part and an exhaust part which are fixedly mounted on the greenhouse support frame; the air blowing part is used for blowing air outside the greenhouse into the greenhouse and providing enough oxygen for growth of fructus forsythiae in the greenhouse, the air blowing part comprises an air blowing assembly, a flow dividing assembly, an air volume adjusting assembly and a heating assembly, and the air blowing assembly is used for blowing the air outside the greenhouse into the greenhouse. The fructus forsythiae greenhouse has the advantages that air at the bottom of the greenhouse vertically flows upwards according to the heat conduction principle, then the rising bottom air is brought out of the greenhouse through air flow horizontally attached to the top of the greenhouse, the direction of the air flow in the greenhouse is regular, vortex is prevented from being generated, meanwhile, air blowing and ventilation can be conducted on the roots of fructus forsythiae, and the ventilation effect is good. The ventilation rate of air at the roots of fructus forsythiae is increased, so that the ventilation efficiency is improved.
Owner:HENAN ACAD OF FORESTRY SCI

A Chinese medicine composition for treating breast nodules and a preparation method of its solubilized preparation

The invention provides a Chinese medicine composition, including Prunella vulgaris, Pinellia tuber, frankincense, bergamot, Cyperus rotundus, Forsythia suspensa, ginger, liquorice, Radix Rehmanniae, and Angelica sinensis. The Chinese medicine composition is used together to regulate qi and blood, take both the symptoms and the root into consideration, and play the effects of soothing the liver and regulating qi, promoting blood circulation and resolving phlegm, softening and dispersing nodules, nourishing blood and calming the mind. It has the advantages of attacking evil without hurting the body, and solves the problem that breast nodules cannot be completely cured. After the Chinese medicine solubilizing preparation of the invention meets water, it can disperse the medicine, increase its solubility, promote the release of the medicine, and enhance the efficacy.
Owner:JIANGSU VOCATIONAL COLLEGE OF MEDICINE

Application of a Chinese medicine composition in medicines for resisting coronavirus, protecting organs and improving immunity

The present invention discloses an application of a traditional Chinese medicine composition in the preparation of a drug for preventing and treating pneumonia caused by the novel coronavirus infection. The traditional Chinese medicine composition of the present invention is mainly composed of forsythia, honeysuckle, isatis root, rhubarb, patchouli, cyperus rotundus, rhodiola rosea and the like, and exerts the overall regulatory advantages of the compound traditional Chinese medicine, organically combines the elimination of pathogenic factors, relief of symptoms and immune regulation to achieve multi-target treatment. Clinical experiments have confirmed that the traditional Chinese medicine composition has a significant inhibitory effect on the prevention and treatment of wild-type and S protein D614G mutant novel coronaviruses, and has a protective effect on the heart and lungs.
Owner:SHIJIAZHUANG YILING PHARMA CO LTD

Agrobacterium rhizogenes-mediated fructus forsythiae hairy root genetic transformation method and application thereof

The invention provides an agrobacterium rhizogenes-mediated forsythia suspensa hairy root genetic transformation method and application thereof, and belongs to the technical field of plant genetic engineering. The method comprises the following steps: introducing an expression vector into agrobacterium rhizogenes, and mixing with an infection solution to prepare an agrobacterium rhizogenes infection solution; the forsythia suspensa stem is put into the agrobacterium rhizogenes infection liquid to be infected for 0.5-1 h through a vacuum infiltration method, and the infected forsythia suspensa stem is cut into a matrix to be subjected to dark culture and then continues to grow till hairy roots are generated; the OD600 value of the agrobacterium rhizogenes infection liquid is 0.5 to 1.0. The method is suitable for an agrobacterium rhizogenes mediated genetic transformation system of the fructus forsythiae, and the system provides technical support for functional gene research, medicinal component analysis and molecular breeding of the fructus forsythiae, and has important significance for promoting genetic improvement and resource utilization of the fructus forsythiae.
Owner:BEIJING FORESTRY UNIVERSITY

Production and preparation method of compound double-flower oral liquid for enhancing palatability

The invention discloses a production and preparation method of palatability-enhanced compound double-flower oral liquid, and relates to the technical field of traditional Chinese medicine preparations. The production and preparation method of the oral liquid comprises the following steps: pretreatment of medicinal materials: taking herba andrographitis, honeysuckle, radix isatidis, fructus forsythiae, honey and dark plum, washing, denucleating and slicing the dark plum (the honey is in a liquid state and does not need to be pretreated), ultrasonic extraction, integrated purification, filtrate collection, dynamic taste modification, sterilization and filling; the method has the advantages that bitter components are accurately neutralized by an innovative gradient inclusion process, qualitative leap of a bitter masking effect is realized, sensory evaluation is verified according to international standards, children acceptance score reaches an excellent level (full score of 10 scores), the core problem that children refer to take medicines due to bitter taste is thoroughly solved, the treatment compliance of patients is remarkably improved, and the treatment cost is reduced. The continuity of medication is ensured, a breakthrough solution is provided for the field of medication for children, and meanwhile, a technical normal form is provided for improvement of medicines similar to bitter taste.
Owner:YUANSHENG SUYUANG BIOLOGICAL SCI TECH BEIJING

Weeping forsythia extract and preparation method thereof

PendingCN119185406AImprove elimination rateAntinoxious agentsSolid solvent extractionPectinaseDPPH
The invention belongs to the technical field of traditional Chinese medicine extraction, and particularly relates to a fructus forsythiae extract and a preparation method thereof.The method comprises the following steps that 1, pretreatment is conducted, specifically, fructus forsythiae is added into water to be braised, then dried and ground, and fructus forsythiae powder is obtained; (2) adding the fructus forsythiae powder into a deep-eutectic solvent, then adding an enzyme preparation, carrying out enzymolysis extraction under an ultrasonic condition, and after the enzymolysis extraction is finished, filtering out precipitates to obtain a fructus forsythiae extract; wherein the enzyme preparation comprises cellulase, pectinase and saccharifying enzyme; the eutectic solvent is prepared from choline chloride, glycerol and polyethylene glycol in a molar ratio of 1: 1: (2-3). The fructus forsythiae extract obtained by the method has a very high elimination rate on DPPH free radicals, superoxide anion free radicals and ABTS free radicals, and can be applied to antioxidant products as a raw material.
Owner:PEACE HOSPITAL AFFILIATED TO CHANGZHI MEDICAL COLLEGE

Astragaloside synergistic composition as well as preparation method and application thereof

The invention discloses an astragaloside synergistic type composition as well as a preparation method and application of the astragaloside synergistic type composition. Comprising the following components: 8 to 16 parts of astragaloside, 20 to 40 parts of a honeysuckle flower extract, 10 to 20 parts of L-carnitine, 0.1 to 0.5 part of selenium yeast, 3 to 8 parts of diammonium glycyrrhizinate, 5 to 15 parts of taurine, 8 to 20 parts of a fructus forsythiae extract, 2 to 7 parts of vitamin E, 12 to 32 parts of hydroxypropyl-beta-cyclodextrin, 2 to 10.5 parts of maltodextrin, 1 to 7 parts of Arabic gum, 10 to 20 parts of lactose, 1 to 3 parts of zinc gluconate and 2 to 5 parts of magnesium stearate. 1-3 parts of vitamin C, 1-5 parts of xanthan gum and 1-3 parts of lecithin. The composition has a wide application prospect in preparation of veterinary drugs or veterinary food additives.
Owner:JIANGXI CHENGBIXIN BIOTECHNOLOGY CO LTD

A fermented traditional chinese medicine feed additive for catfish and its preparation method and application

A fermented traditional Chinese medicine feed additive for catfish, its preparation method, and its application are disclosed, relating to the field of aquatic feed additives. The preparation method involves activating and expanding the culture of *Saccharomyces cerevisiae*, *Bacillus subtilis*, and *Lactobacillus plantarum*; pulverizing *Paeonia suffruticosa* leaves, *Smilax china*, *Scutellaria baicalensis*, *Rhus chinensis*, hawthorn, *Polygonum cuspidatum*, ginkgo, and forsythia suspensa* to obtain traditional Chinese medicine powders; preparing a solid fermentation medium using the traditional Chinese medicine powders, soybean meal powder, corn cob granules, and wheat bran; inoculating *Saccharomyces cerevisiae* seed culture and *Bacillus subtilis* seed culture for aerobic fermentation; and inoculating *Lactobacillus plantarum* seed culture for anaerobic fermentation to obtain the fermented traditional Chinese medicine feed additive. The resulting fermented traditional Chinese medicine feed additive promotes the absorption and metabolic elimination of enrofloxacin in catfish, shortens the withdrawal period, has preventive and adjunctive therapeutic effects on bacterial diseases in catfish, promotes growth, reduces feed conversion ratio, and improves survival rate.
Owner:LUOYANG NORMAL UNIV

Traditional Chinese medicine composition for preventing and treating light and moderate varicocele and preparation method thereof

The invention discloses a traditional Chinese medicine composition for preventing and treating light and moderate varicocele and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 12 to 30 parts of radix paeoniae rubra, 9 to 24 parts of peach kernel, 9 to 24 parts of spina gleditsiae, 9 to 24 parts of radix cyathulae, 6 to 18 parts of cassia twig, 9 to 24 parts of fructus forsythiae, 6 to 18 parts of thunberg fritillary bulb, 6 to 18 parts of rhodiola rosea, 6 to 18 parts of semen aesculi and 3 to 15 parts of raw liquorice. After the traditional Chinese medicine composition provided by the invention is adopted for treatment, the spermatovenous reflux time is remarkably shortened, the semen quality including semen volume, sperm density and sperm motility is remarkably improved, the total effective rate of treatment is higher than that of other prescriptions, the living quality of a patient is remarkably improved, the medicine safety is high, and the varicocele can be effectively treated.
Owner:THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM

An anti-aging composition and its application in skin care field

The present invention relates to the technical field of skin care products, and specifically to an anti-aging composition and its application in the field of skin care. The present invention provides an anti-aging composition, which comprises the following components by mass: 0.01 to 2 parts of ergothioneine, 5 to 30 parts of plant extracts and 2 to 5 parts of a second antioxidant component, wherein the second antioxidant component is any one of asiaticoside, resveratrol, glabridin, glutathione and bosaicin, and the plant extract is any one or more of licorice (GLYCYRRHIZA URALENSIS) extract, forsythia (FORSYTHIA SUSPENSA) extract, viola mandshurica (VIOLA MANDSHURICA) flower extract, chuanxiong (LIGUSTICUM CHUANXIONG) extract and cynanchum atratum (CYNANCHUM ATRATUM) extract. The anti-aging composition is compounded with ergothioneine and a second antioxidant, and then an effective plant extract is added, so that the components of the anti-aging composition can reduce the overall raw material cost of the skin care product through good synergy and maintain a good anti-aging effect.
Owner:CHENGDU QIANTANG BIOMEDICAL TECHNOLOGY CO LTD

A method for distilling volatile oil from Forsythia suspensa

This invention relates to the field of separation and purification, and particularly to a distillation method for Forsythia suspensa volatile oil, comprising the following steps: Step (1) Crush dried Forsythia suspensa fruit and mix it with water at a mass ratio of 1:3-5, grinding until the particle size D90≤50μm to obtain Forsythia suspensa slurry; Step (2) Add porous medium A particles with a particle size of 0.5-1mm and water-absorbing medium B to the Forsythia suspensa slurry obtained in Step (2), stir and mix for 20-40min to obtain a cake; Step (3) Mix the cake with moistened porous medium C particles with a particle size of 1-3cm, then load it into a distillation kettle for distillation, collect the distillate and separate to obtain Forsythia suspensa volatile oil. This scheme optimizes the distillation process, improves distillation efficiency, and solves the clogging problem caused by excessively fine grinding of raw materials, thereby meeting the industrial production demand for efficient and stable extraction of Forsythia suspensa volatile oil.
Owner:JISHUI COUNTY JINHAI NATURAL SPICE OIL TECHCO

Forsythia suspensa alkaloid B and its preparation method and anti-inflammatory and antiviral applications

The invention discloses a forsythia alkaloid B and its preparation method and anti-inflammatory and antiviral applications, belonging to the technical field of pharmaceutical chemistry. The forsythia alkaloid B is a norcisan-type diterpene alkaloid with a molecular formula of C 17 H 23 NO2, the structural formula is as follows. The invention is beneficial in that: the forsythia alkaloid B is separated from the fruit of forsythia by an innovative extraction and separation process, the forsythia alkaloid B has a novel structure, and has good anti-inflammatory and anti-H9N2, H5N1 and H1N1 influenza virus activities, providing a new material basis for the research on the anti-inflammatory and antiviral activities of forsythia. #imgabs0#Forsythia alkaloid B.
Owner:YANTAI UNIV

Preparation method of Qingre Jiedu oral liquid

This invention discloses a method for preparing a heat-clearing and detoxifying oral liquid. Honeysuckle and Scutellaria baicalensis are pulverized and sieved, then enzymatically hydrolyzed with water, ultrasonically extracted, and filtered to obtain extract A. Scrophularia ningpoensis, Rehmannia glutinosa, Forsythia suspensa, Gardenia jasminoides, Viola yedoensis, Gentiana scabra, Isatis indigotica, Anemarrhena asphodeloides, and Ophiopogon japonicus are warm-soaked in water and flash-extracted, then filtered to obtain extract B. Gypsum is crushed, decocted with water, and filtered to obtain extract C. The extracts are combined, concentrated, and sequentially clarified using a flocculant, followed by inorganic ceramic membrane microfiltration and organic ultrafiltration. The clarified liquid is then concentrated, flavoring agents and preservatives are added, the pH is adjusted, the volume is adjusted, filtered, filled, and sterilized to obtain the finished product. This invention utilizes a composite clarification process—low-temperature ultrasonic-enzymatic extraction of honeysuckle and Scutellaria baicalensis, clarification using a flocculant, inorganic ceramic membrane microfiltration, and organic ultrafiltration—to improve the extraction rate of effective components, effectively remove large molecular impurities such as tannins, proteins, and pectin, and significantly improve the clarity and stability of the product.
Owner:SICHUAN GOODDOCTOR PHARMA GRP

Compound tea capable of clearing away heat and toxic materials based on multi-layer scenting process and preparation method of compound tea

The invention relates to the technical field of tea substitutes, in particular to compound tea capable of clearing away heat and toxic materials based on a multi-layer scenting process and a preparation method. The compound tea capable of clearing away heat and toxic materials comprises the following raw material components in parts by weight: 1-5 parts of acer truncatum, 1-5 parts of honeysuckle, 1-5 parts of fructus forsythiae, 1-3 parts of platycodon grandiflorum, 8-15 parts of fresh rhizoma phragmitis, 1-3 parts of liquorice, 5-10 parts of astragalus membranaceus, 1-5 parts of penthorum chinense pursh, 12-30 parts of black tea, 0.5-2 parts of ginseng, 2-4 parts of cape jasmine, 1-10 parts of dandelion, 1-5 parts of selfheal, 5-10 parts of semen cassiae and 3-8 parts of houttuynia cordata. The compound tea capable of clearing away heat and toxic materials adopts a multi-layer scenting process, the loss of active ingredients in the obtained compound tea capable of clearing away heat and toxic materials is small, the flavor is rich, the effects of multiple components are mutually cooperated and promoted, and the compound tea has a very good conditioning effect on the sub-health states of modern people, such as vigorous liver fire, metabolic imbalance and the like.
Owner:SHANGHAI ZHONGNATANG HEALTH TECHNOLOGY CO LTD

Traditional Chinese medicine composition for treating acute myocardial infarction, pharmaceutical preparation and application thereof

The invention discloses a traditional Chinese medicine composition for treating acute myocardial infarction, a pharmaceutical preparation and application thereof and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from, by weight, 9-18 parts of ginseng, 3-6 parts of pseudo-ginseng, 9-18 parts of ligusticum wallichii, 12-24 parts of radix achyranthis bidentatae, 6-12 parts of fructus forsythiae and 9-18 parts of radix curcumae. Compared with the prior art, the traditional Chinese medicine composition disclosed by the invention has the beneficial effects that (1) the traditional Chinese medicine composition provided by the invention can reduce the myocardial infarction area after ischemia, inhibit myocardial fibrosis and improve heart structure and function changes caused by acute ischemic injury; and (2) the traditional Chinese medicine composition provided by the invention can effectively inhibit oxidative stress reaction and relieve mitochondrial injury, thereby playing a role in protecting the heart. And (3) the traditional Chinese medicine composition has the advantage of good safety and can be taken for a long time.
Owner:XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI

Efficient pest control device for forsythia suspensa planting

The utility model relates to the technical field of prevention and control devices, and discloses an efficient pest prevention and control device for forsythia suspensa planting, which comprises a frame body, a connecting shell is fixedly connected to the bottom of the right end of the frame body, a plurality of power grids are fixedly connected to the edge of the bottom end of the connecting shell, and a trap lamp is fixedly connected to the middle of the bottom end of the connecting shell. A telescopic rod is fixedly connected to the top of the right end of the frame body, a push disc is fixedly connected to the top end of the telescopic rod, a plurality of push rods are fixedly connected to the edge of the bottom end of the push disc, a push frame is fixedly connected to the bottom ends of the push rods, and a first cleaning ring is fixedly connected to the middle of the push frame. According to the device, the trap lamp attracts pests to the power grid to be killed, the power grid and the trap lamp accumulate dirt after long-term use, the telescopic rod is started to pull down the push disc, the push rod and the push frame are driven to move, the first cleaning ring and the second cleaning ring clean the trap lamp and the outer wall of the power grid, the killing efficiency is improved, and it is ensured that the planting effect meets the requirement.
Owner:HEBEI HANCHAO AGRI TECH DEV CO LTD

Method for improving survival rate of forsythia tender branch cutting seedling

This invention belongs to the field of plant seedling technology, specifically relating to a method for improving the survival rate of Forsythia suspensa cuttings. Specifically, fruiting mother trees are selected, and semi-lignified branches of the current year are collected as cuttings, retaining plump buds. The cuttings are soaked in a rooting agent compound solution and then dried for later use. The treated cuttings are then inserted into a gradient substrate and thoroughly watered after planting. The stomatal conductance of the cutting leaves and the electrical conductivity at the base of the cuttings are monitored in real time. The substrate temperature, spraying frequency, shading rate, and ventilation are adaptively adjusted in a closed-loop manner according to the physiological thresholds of different rooting stages of Forsythia suspensa cuttings. Stress-resistant fertilizer is applied according to the physiological state of the cuttings, and disease control and daily management are carried out. This method improves the survival rate of Forsythia suspensa cuttings, reduces the rate of cutting rot, exhibits strong environmental adaptability, and high seedling stability.
Owner:LONGNAN HONGFENG AGRICULTURAL SCIENCE & TECHNOLOGY CO LTD

Compound cinnabar freeze-dried powder and preparation process thereof

This invention provides a compound Phellodendron amurense freeze-dried powder and its preparation process, relating to the field of deep processing technology of compound Phellodendron amurense extract. The preparation process includes the following steps: 80±10 parts by weight of Forsythia suspensa, 40±5 parts by weight of Phellodendron amurense, 40±5 parts by weight of Lonicera japonica, 40±5 parts by weight of Taraxacum mongolicum, and 2.4±0.3 parts by weight of Scolopendra subspinipes. S1: Take a certain weight of the above five ingredients, add water and decoct, concentrate to a clear extract with a relative density of 1.10-1.15, add ethanol to make the alcohol content reach 70%, let stand, concentrate until there is no alcohol odor, and obtain compound Phellodendron amurense ethanol extract; S2: Take the compound Phellodendron amurense ethanol extract, add water to a certain volume, refrigerate, filter, and obtain compound Phellodendron amurense freeze-dried stock solution; S3: Take the compound Phellodendron amurense freeze-dried stock solution, fill, and freeze-dry to obtain compound Phellodendron amurense freeze-dried powder. The compound Phellodendron amurense freeze-dried powder prepared by this invention solves the problems of existing coatings being non-sterile, unstable, and inconvenient to transport.
Owner:SHANDONG HANFANG PHARMA

A drug that antagonizes bacterial endotoxins, its preparation method and application

PendingCN122075586AEnhance synergistic antagonismPreserve heat sensitivityOrganic active ingredientsAntibacterial agentsBacterial endotoxinIbuprofen
This invention provides a drug for antagonizing bacterial endotoxins, its preparation method, and its application, belonging to the biomedical field. The composition consists of 25-55 parts of dried powdered traditional Chinese medicine extract, 25-70 parts of mixed essential oil powder, and 40-90 parts of lentinan powder. The traditional Chinese medicine extract is prepared by decoction of Scutellaria baicalensis, Lonicera japonica, Forsythia suspensa, and Isatis indigotica under reduced pressure at low temperature and spray drying. The mixed essential oil powder is prepared by encapsulating peppermint oil and eucalyptus oil with gelatin and hydroxypropyl cellulose and then spray drying under high pressure. This invention, through specific formulation and processing, significantly enhances the synergistic antagonistic effect of each component against endotoxins. Experiments show that this composition exhibits antagonistic activity far superior to ibuprofen in vitro; in vivo, it significantly reduces the endotoxin content in the plasma of 817 broiler chickens, rapidly alleviates LPS-induced fever and diarrhea, and improves decreased growth performance. Therefore, this invention is of great significance for reducing antibiotic dependence and improving the efficiency of livestock and poultry farming.
Owner:SHANDONG SINDER TECH CO LTD +2

Traditional Chinese medicine composition for preventing and treating avian pathogenic escherichia coli as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for preventing and treating avian pathogenic escherichia coli as well as a preparation method and application thereof, and relates to the technical field of veterinary drugs. According to the invention, screening is carried out through subtraction genomics and reverse network pharmacology, and based on the compatibility theory of monarch, minister, assistant and guide and the traditional Chinese veterinary medicine and pharmacy differentiation theory, a traditional Chinese medicine composition, namely the radix angelicae and fructus forsythiae intestine health formula, for preventing and treating avian pathogenic escherichia coli is formed. According to the traditional Chinese medicine composition, fructus forsythiae and radix angelicae are used as monarch drugs, radix isatidis and clinopodium polycephalum are used as ministerial drugs, fructus aurantii immaturus, mint and plantain herb are used as adjuvant drugs, and liquorice is used as a conductant drug, so that the traditional Chinese medicine composition can inhibit reproduction of avian pathogenic escherichia coli, destroy formation of biological membranes of the avian pathogenic escherichia coli and relieve pathological injuries of diseased poultry caused by APEC; the traditional Chinese medicine composition has a good treatment effect on avian pathogenic escherichia coli.
Owner:SHANDONG AGRICULTURAL UNIVERSITY

A medicament for treating infectious bursal disease and its preparation method and application

ActiveCN119424555BAntiviralsAluminium/calcium/magnesium active ingredientsInfectious bursal disease virus IBDVVariant strain
This invention relates to a traditional Chinese medicine preparation for treating infectious bursal disease (IBD), its preparation method, and its application. The preparation comprises the following components: Astragalus membranaceus 45-50 parts, Rehmannia glutinosa 30-45 parts, Isatis indigotica 25-30 parts, Isatis tinctoria 25-30 parts, Gypsum fibrosum 10-45 parts, Lonicera japonica 10-20 parts, Forsythia suspensa 10-30 parts, Taraxacum mongolicum 10-20 parts, Atractylodes macrocephala 15-20 parts, Paeonia lactiflora 15-30 parts, Lilium brownii 15 parts, Anemarrhena asphodeloides 15 parts, and Glycyrrhiza uralensis 10-30 parts. The preparation is achieved through extraction and concentration processes and is effective in treating IBD in chickens caused by both traditional infectious bursal disease virus (IBDV) and novel variant infectious bursal disease virus (nvvIBDV). This medicine significantly improves the cure rate against both traditional and variant strains, showing a particularly significant advantage in treating variant strains.
Owner:SHANDONG SINDER TECH CO LTD +1

Traditional Chinese medicine compound for treating viral myocarditis

ActiveCN121401357BAntiviralsCardiovascular disorderViral MyocarditisCitrus medica
This invention provides a traditional Chinese medicine compound for treating viral myocarditis, belonging to the field of traditional Chinese medicine pharmaceutical technology. The compound consists of Forsythia suspensa, Fagopyrum dibotrys, Pseudostellaria heterophylla, Rhodiola rosea, Citrus medica, Allium macrostemon, Poria cocos, Gynostemma pentaphyllum, Salvia miltiorrhiza, Dalbergia odorifera, Cynanchum paniculatum, and Valeriana. This traditional Chinese medicine compound exhibits significant protective effects against viral myocarditis, specifically by significantly reducing damage to H9c2 cardiomyocytes caused by CVB3 virus. Its mechanism of action is closely related to downregulating the expression of inflammatory factors TNF-α and IL-6 and inhibiting the inflammatory response. Simultaneously, within the experimental concentration range, the compound shows no toxicity to cardiomyocytes, demonstrating good biocompatibility. Furthermore, this compound can significantly reduce myocardial tissue damage in a viral myocarditis model mouse by inhibiting the in vivo inflammatory response and regulating oxidative stress imbalance, providing a safe and effective new treatment option for the clinical treatment of viral myocarditis.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

Feed additive for improving transportation stress reaction of ruminants as well as preparation method and application of feed additive

The invention provides a feed additive for improving transportation stress reaction of ruminants as well as a preparation method and application of the feed additive, and relates to the technical field of functional feed additives. The feed additive comprises a probiotic composition and a traditional Chinese medicine fermented material, the probiotic composition is composed of bacillus subtilis, enterococcus faecium and saccharomyces cerevisiae, and the traditional Chinese medicine fermented material is composed of codonopsis pilosula, fructus forsythiae, radix bupleuri, soybean meal and bran. The feed additive can influence the physiological indexes, biochemical indexes and blood indexes of the ruminants and promote the indexes to recover to the level before transportation, so that the transportation stress response of the ruminants is greatly improved.
Owner:HUBEI HUADA REAL TECH CO LTD

Automatic transplanting machine for forsythia suspensa seedlings

The utility model belongs to the technical field of forsythia suspensa seedling transplanting, and particularly relates to an automatic forsythia suspensa seedling transplanting machine which comprises a traction support frame and a pit digging drill, the pit digging drill is obliquely installed on one side of the traction support frame, a protective conical barrel is arranged at the top end of the traction support frame, a connecting frame is arranged in the protective conical barrel, and the connecting frame is connected with the traction support frame. Side pruning blades are fixedly connected to the two sides of the connecting frame, a bottom pruning blade is fixedly connected to the top end of the connecting frame, a limiting ring net is arranged above the bottom pruning blade, and a suspension fixing rod is fixedly connected to the top end of the limiting ring net; the lateral pruning blades and the bottom pruning blades can quickly prune the roots, extending outwards to be too long, of the fructus forsythiae seedlings, and dense root clusters of the fructus forsythiae seedlings are limited by means of the limiting ring net and the suspension fixing rods, so that the phenomenon that the dense root clusters of the fructus forsythiae seedlings are excessively pruned by the bottom pruning blades is avoided; the hanging fixing rod and the limiting guide plate are matched to limit the forsythia suspense seedling plant rod, so that the lateral trimming blade is prevented from excessively trimming the lateral root of the forsythia suspense seedling.
Owner:JINQIAO TECH (HEBEI) CO LTD

Targeted phlegm clearing combustion type chronic obstructive pulmonary disease traditional Chinese medicine fumigant and preparation process thereof

The invention relates to the technical field of traditional Chinese medicines, in particular to a combustion type chronic obstructive pulmonary disease traditional Chinese medicine fumigant for targeted phlegm clearing, which is characterized in that the traditional Chinese medicine formula of the fumigant comprises platycodon grandiflorum, bulbus fritillariae cirrhosae, fructus perillae, flos farfarae, almond, radix stemonae and liquorice. The medicine effect is lasting and stable, the bulbus fritillariae cirrhosae or the green fritillary bulb is selected as a bulbus fritillariae cirrhosae source, the bulbus fritillariae cirrhosae and the green fritillary bulb have no obvious difference in phlegm clearing effect, but the bulbus fritillariae cirrhosae is slightly excellent in medicine effect durability, the medicine action time is prolonged, and the treatment effect is improved.
Owner:TIANMA ANHUI SINOPHARM TECH CO LTD

A net face acne traditional Chinese medicine composition and application and gel containing the composition

The application discloses a kind of clean face acne traditional Chinese medicine composition and application and gel containing the composition, it is related to clean face acne product technical field.The clean face acne traditional Chinese medicine composition of the application, including the following weight parts of raw material composition: 5-60 parts of forsythia suspensa extract, 3-50 parts of rhubarb extract, 2-50 parts of sophora flavescens extract, 5-60 parts of radix lithospermi extract, 1-25 parts of sparganium extract, 5-60 parts of herba violae extract, 3-50 parts of scutellaria baicalensis georgi extract, 2-50 parts of herba taraxaci extract, 2-50 parts of red root of tree peony extract, 1-25 parts of bletilla striata extract, 1-25 parts of mentha haplocalyx extract;Meanwhile, the gel containing the composition is disclosed.The application effectively realizes bacteriostasis for traditional Chinese medicine preparation, reduces skin inflammatory response, shortens acne subsidence time;Regulate sebaceous secretion, improve skin metabolism, accelerate the subsidence of acne;Redness average value before and after use and acne volume contrast is remarkable, and curative effect is exact.
Owner:YIWEIAN BIOTECHNOLOGY (CHENGDU) CO LTD