183 results about "Forsythia suspensa" patented technology

The invention belongs to the field of microorganisms and fermentation, and relates to a biological preparation, a preparation method thereof and application of the biological preparation in preparation of products for inhibiting escherichia coli. And the biological agent is a co-fermentation product of fructus forsythiae and bacillus amyloliquefaciens (Bacillus amyloliquefaciens). The biological preparation provided by the invention can obviously improve the secretion of IFN-alpha in a mouse body, reduce the production of IL-1beta, IL-6 and TNF-alpha, increase the proportion of CD3 + CD4 + and CD3 + CD8 + T cells, and improve the expression of ZO-1 and Occludin in duodenum and jejunum. Compared with single use of fructus forsythiae and bacillus amyloliquefaciens, the biological preparation shows a stronger synergistic effect, can effectively prevent and inhibit escherichia coli infection, and is not easy to generate drug resistance. The preparation method is simple, raw materials are easy to obtain, and the feed additive is suitable for developing antibacterial drugs and feed additives.

The invention belongs to the technical field of traditional Chinese medicine research, and particularly relates to a traditional Chinese medicine composition for treating cold and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 7-11 parts of cistanche, 10-14 parts of dried ginger, 7-11 parts of pogostemon cablin, 13-17 parts of pericarpium citri reticulatae, 10-14 parts of polygonum cuspidatum, 7-11 parts of bistort rhizome, 8-12 parts of fructus forsythiae, 28-32 parts of honeysuckle, 10-14 parts of radix bupleuri, 10-14 parts of blackberry lily, 8-12 parts of notopterygium root, 7-11 parts of radix angelicae pubescentis, 7-11 parts of divaricate saposhnikovia root, 7-11 parts of schizonepeta, 7-11 parts of radix angelicae, 10-14 parts of fingered citron, 7-11 parts of perilla stem, 13-17 parts of artemisia apiacea and 10-14 parts of folium mori. The traditional Chinese medicine composition has a better curative effect on cold-dampness cold.

The invention provides an agrobacterium rhizogenes-mediated forsythia suspensa hairy root genetic transformation method and application thereof, and belongs to the technical field of plant genetic engineering. The method comprises the following steps: introducing an expression vector into agrobacterium rhizogenes, and mixing with an infection solution to prepare an agrobacterium rhizogenes infection solution; the forsythia suspensa stem is put into the agrobacterium rhizogenes infection liquid to be infected for 0.5-1 h through a vacuum infiltration method, and the infected forsythia suspensa stem is cut into a matrix to be subjected to dark culture and then continues to grow till hairy roots are generated; the OD600 value of the agrobacterium rhizogenes infection liquid is 0.5 to 1.0. The method is suitable for an agrobacterium rhizogenes mediated genetic transformation system of the fructus forsythiae, and the system provides technical support for functional gene research, medicinal component analysis and molecular breeding of the fructus forsythiae, and has important significance for promoting genetic improvement and resource utilization of the fructus forsythiae.

The invention discloses a production and preparation method of palatability-enhanced compound double-flower oral liquid, and relates to the technical field of traditional Chinese medicine preparations. The production and preparation method of the oral liquid comprises the following steps: pretreatment of medicinal materials: taking herba andrographitis, honeysuckle, radix isatidis, fructus forsythiae, honey and dark plum, washing, denucleating and slicing the dark plum (the honey is in a liquid state and does not need to be pretreated), ultrasonic extraction, integrated purification, filtrate collection, dynamic taste modification, sterilization and filling; the method has the advantages that bitter components are accurately neutralized by an innovative gradient inclusion process, qualitative leap of a bitter masking effect is realized, sensory evaluation is verified according to international standards, children acceptance score reaches an excellent level (full score of 10 scores), the core problem that children refer to take medicines due to bitter taste is thoroughly solved, the treatment compliance of patients is remarkably improved, and the treatment cost is reduced. The continuity of medication is ensured, a breakthrough solution is provided for the field of medication for children, and meanwhile, a technical normal form is provided for improvement of medicines similar to bitter taste.

The invention discloses an astragaloside synergistic type composition as well as a preparation method and application of the astragaloside synergistic type composition. Comprising the following components: 8 to 16 parts of astragaloside, 20 to 40 parts of a honeysuckle flower extract, 10 to 20 parts of L-carnitine, 0.1 to 0.5 part of selenium yeast, 3 to 8 parts of diammonium glycyrrhizinate, 5 to 15 parts of taurine, 8 to 20 parts of a fructus forsythiae extract, 2 to 7 parts of vitamin E, 12 to 32 parts of hydroxypropyl-beta-cyclodextrin, 2 to 10.5 parts of maltodextrin, 1 to 7 parts of Arabic gum, 10 to 20 parts of lactose, 1 to 3 parts of zinc gluconate and 2 to 5 parts of magnesium stearate. 1-3 parts of vitamin C, 1-5 parts of xanthan gum and 1-3 parts of lecithin. The composition has a wide application prospect in preparation of veterinary drugs or veterinary food additives.

A fermented traditional Chinese medicine feed additive for catfish, its preparation method, and its application are disclosed, relating to the field of aquatic feed additives. The preparation method involves activating and expanding the culture of *Saccharomyces cerevisiae*, *Bacillus subtilis*, and *Lactobacillus plantarum*; pulverizing *Paeonia suffruticosa* leaves, *Smilax china*, *Scutellaria baicalensis*, *Rhus chinensis*, hawthorn, *Polygonum cuspidatum*, ginkgo, and forsythia suspensa* to obtain traditional Chinese medicine powders; preparing a solid fermentation medium using the traditional Chinese medicine powders, soybean meal powder, corn cob granules, and wheat bran; inoculating *Saccharomyces cerevisiae* seed culture and *Bacillus subtilis* seed culture for aerobic fermentation; and inoculating *Lactobacillus plantarum* seed culture for anaerobic fermentation to obtain the fermented traditional Chinese medicine feed additive. The resulting fermented traditional Chinese medicine feed additive promotes the absorption and metabolic elimination of enrofloxacin in catfish, shortens the withdrawal period, has preventive and adjunctive therapeutic effects on bacterial diseases in catfish, promotes growth, reduces feed conversion ratio, and improves survival rate.

The invention discloses a traditional Chinese medicine composition for preventing and treating light and moderate varicocele and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 12 to 30 parts of radix paeoniae rubra, 9 to 24 parts of peach kernel, 9 to 24 parts of spina gleditsiae, 9 to 24 parts of radix cyathulae, 6 to 18 parts of cassia twig, 9 to 24 parts of fructus forsythiae, 6 to 18 parts of thunberg fritillary bulb, 6 to 18 parts of rhodiola rosea, 6 to 18 parts of semen aesculi and 3 to 15 parts of raw liquorice. After the traditional Chinese medicine composition provided by the invention is adopted for treatment, the spermatovenous reflux time is remarkably shortened, the semen quality including semen volume, sperm density and sperm motility is remarkably improved, the total effective rate of treatment is higher than that of other prescriptions, the living quality of a patient is remarkably improved, the medicine safety is high, and the varicocele can be effectively treated.

This invention relates to the field of separation and purification, and particularly to a distillation method for Forsythia suspensa volatile oil, comprising the following steps: Step (1) Crush dried Forsythia suspensa fruit and mix it with water at a mass ratio of 1:3-5, grinding until the particle size D90≤50μm to obtain Forsythia suspensa slurry; Step (2) Add porous medium A particles with a particle size of 0.5-1mm and water-absorbing medium B to the Forsythia suspensa slurry obtained in Step (2), stir and mix for 20-40min to obtain a cake; Step (3) Mix the cake with moistened porous medium C particles with a particle size of 1-3cm, then load it into a distillation kettle for distillation, collect the distillate and separate to obtain Forsythia suspensa volatile oil. This scheme optimizes the distillation process, improves distillation efficiency, and solves the clogging problem caused by excessively fine grinding of raw materials, thereby meeting the industrial production demand for efficient and stable extraction of Forsythia suspensa volatile oil.

This invention discloses a method for preparing a heat-clearing and detoxifying oral liquid. Honeysuckle and Scutellaria baicalensis are pulverized and sieved, then enzymatically hydrolyzed with water, ultrasonically extracted, and filtered to obtain extract A. Scrophularia ningpoensis, Rehmannia glutinosa, Forsythia suspensa, Gardenia jasminoides, Viola yedoensis, Gentiana scabra, Isatis indigotica, Anemarrhena asphodeloides, and Ophiopogon japonicus are warm-soaked in water and flash-extracted, then filtered to obtain extract B. Gypsum is crushed, decocted with water, and filtered to obtain extract C. The extracts are combined, concentrated, and sequentially clarified using a flocculant, followed by inorganic ceramic membrane microfiltration and organic ultrafiltration. The clarified liquid is then concentrated, flavoring agents and preservatives are added, the pH is adjusted, the volume is adjusted, filtered, filled, and sterilized to obtain the finished product. This invention utilizes a composite clarification process—low-temperature ultrasonic-enzymatic extraction of honeysuckle and Scutellaria baicalensis, clarification using a flocculant, inorganic ceramic membrane microfiltration, and organic ultrafiltration—to improve the extraction rate of effective components, effectively remove large molecular impurities such as tannins, proteins, and pectin, and significantly improve the clarity and stability of the product.

The invention relates to the technical field of tea substitutes, in particular to compound tea capable of clearing away heat and toxic materials based on a multi-layer scenting process and a preparation method. The compound tea capable of clearing away heat and toxic materials comprises the following raw material components in parts by weight: 1-5 parts of acer truncatum, 1-5 parts of honeysuckle, 1-5 parts of fructus forsythiae, 1-3 parts of platycodon grandiflorum, 8-15 parts of fresh rhizoma phragmitis, 1-3 parts of liquorice, 5-10 parts of astragalus membranaceus, 1-5 parts of penthorum chinense pursh, 12-30 parts of black tea, 0.5-2 parts of ginseng, 2-4 parts of cape jasmine, 1-10 parts of dandelion, 1-5 parts of selfheal, 5-10 parts of semen cassiae and 3-8 parts of houttuynia cordata. The compound tea capable of clearing away heat and toxic materials adopts a multi-layer scenting process, the loss of active ingredients in the obtained compound tea capable of clearing away heat and toxic materials is small, the flavor is rich, the effects of multiple components are mutually cooperated and promoted, and the compound tea has a very good conditioning effect on the sub-health states of modern people, such as vigorous liver fire, metabolic imbalance and the like.

The invention discloses a traditional Chinese medicine composition for treating acute myocardial infarction, a pharmaceutical preparation and application thereof and belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from, by weight, 9-18 parts of ginseng, 3-6 parts of pseudo-ginseng, 9-18 parts of ligusticum wallichii, 12-24 parts of radix achyranthis bidentatae, 6-12 parts of fructus forsythiae and 9-18 parts of radix curcumae. Compared with the prior art, the traditional Chinese medicine composition disclosed by the invention has the beneficial effects that (1) the traditional Chinese medicine composition provided by the invention can reduce the myocardial infarction area after ischemia, inhibit myocardial fibrosis and improve heart structure and function changes caused by acute ischemic injury; and (2) the traditional Chinese medicine composition provided by the invention can effectively inhibit oxidative stress reaction and relieve mitochondrial injury, thereby playing a role in protecting the heart. And (3) the traditional Chinese medicine composition has the advantage of good safety and can be taken for a long time.

The utility model relates to the technical field of prevention and control devices, and discloses an efficient pest prevention and control device for forsythia suspensa planting, which comprises a frame body, a connecting shell is fixedly connected to the bottom of the right end of the frame body, a plurality of power grids are fixedly connected to the edge of the bottom end of the connecting shell, and a trap lamp is fixedly connected to the middle of the bottom end of the connecting shell. A telescopic rod is fixedly connected to the top of the right end of the frame body, a push disc is fixedly connected to the top end of the telescopic rod, a plurality of push rods are fixedly connected to the edge of the bottom end of the push disc, a push frame is fixedly connected to the bottom ends of the push rods, and a first cleaning ring is fixedly connected to the middle of the push frame. According to the device, the trap lamp attracts pests to the power grid to be killed, the power grid and the trap lamp accumulate dirt after long-term use, the telescopic rod is started to pull down the push disc, the push rod and the push frame are driven to move, the first cleaning ring and the second cleaning ring clean the trap lamp and the outer wall of the power grid, the killing efficiency is improved, and it is ensured that the planting effect meets the requirement.

This invention belongs to the field of plant seedling technology, specifically relating to a method for improving the survival rate of Forsythia suspensa cuttings. Specifically, fruiting mother trees are selected, and semi-lignified branches of the current year are collected as cuttings, retaining plump buds. The cuttings are soaked in a rooting agent compound solution and then dried for later use. The treated cuttings are then inserted into a gradient substrate and thoroughly watered after planting. The stomatal conductance of the cutting leaves and the electrical conductivity at the base of the cuttings are monitored in real time. The substrate temperature, spraying frequency, shading rate, and ventilation are adaptively adjusted in a closed-loop manner according to the physiological thresholds of different rooting stages of Forsythia suspensa cuttings. Stress-resistant fertilizer is applied according to the physiological state of the cuttings, and disease control and daily management are carried out. This method improves the survival rate of Forsythia suspensa cuttings, reduces the rate of cutting rot, exhibits strong environmental adaptability, and high seedling stability.

This invention provides a compound Phellodendron amurense freeze-dried powder and its preparation process, relating to the field of deep processing technology of compound Phellodendron amurense extract. The preparation process includes the following steps: 80±10 parts by weight of Forsythia suspensa, 40±5 parts by weight of Phellodendron amurense, 40±5 parts by weight of Lonicera japonica, 40±5 parts by weight of Taraxacum mongolicum, and 2.4±0.3 parts by weight of Scolopendra subspinipes. S1: Take a certain weight of the above five ingredients, add water and decoct, concentrate to a clear extract with a relative density of 1.10-1.15, add ethanol to make the alcohol content reach 70%, let stand, concentrate until there is no alcohol odor, and obtain compound Phellodendron amurense ethanol extract; S2: Take the compound Phellodendron amurense ethanol extract, add water to a certain volume, refrigerate, filter, and obtain compound Phellodendron amurense freeze-dried stock solution; S3: Take the compound Phellodendron amurense freeze-dried stock solution, fill, and freeze-dry to obtain compound Phellodendron amurense freeze-dried powder. The compound Phellodendron amurense freeze-dried powder prepared by this invention solves the problems of existing coatings being non-sterile, unstable, and inconvenient to transport.

This invention provides a drug for antagonizing bacterial endotoxins, its preparation method, and its application, belonging to the biomedical field. The composition consists of 25-55 parts of dried powdered traditional Chinese medicine extract, 25-70 parts of mixed essential oil powder, and 40-90 parts of lentinan powder. The traditional Chinese medicine extract is prepared by decoction of Scutellaria baicalensis, Lonicera japonica, Forsythia suspensa, and Isatis indigotica under reduced pressure at low temperature and spray drying. The mixed essential oil powder is prepared by encapsulating peppermint oil and eucalyptus oil with gelatin and hydroxypropyl cellulose and then spray drying under high pressure. This invention, through specific formulation and processing, significantly enhances the synergistic antagonistic effect of each component against endotoxins. Experiments show that this composition exhibits antagonistic activity far superior to ibuprofen in vitro; in vivo, it significantly reduces the endotoxin content in the plasma of 817 broiler chickens, rapidly alleviates LPS-induced fever and diarrhea, and improves decreased growth performance. Therefore, this invention is of great significance for reducing antibiotic dependence and improving the efficiency of livestock and poultry farming.

The invention discloses a traditional Chinese medicine composition for preventing and treating avian pathogenic escherichia coli as well as a preparation method and application thereof, and relates to the technical field of veterinary drugs. According to the invention, screening is carried out through subtraction genomics and reverse network pharmacology, and based on the compatibility theory of monarch, minister, assistant and guide and the traditional Chinese veterinary medicine and pharmacy differentiation theory, a traditional Chinese medicine composition, namely the radix angelicae and fructus forsythiae intestine health formula, for preventing and treating avian pathogenic escherichia coli is formed. According to the traditional Chinese medicine composition, fructus forsythiae and radix angelicae are used as monarch drugs, radix isatidis and clinopodium polycephalum are used as ministerial drugs, fructus aurantii immaturus, mint and plantain herb are used as adjuvant drugs, and liquorice is used as a conductant drug, so that the traditional Chinese medicine composition can inhibit reproduction of avian pathogenic escherichia coli, destroy formation of biological membranes of the avian pathogenic escherichia coli and relieve pathological injuries of diseased poultry caused by APEC; the traditional Chinese medicine composition has a good treatment effect on avian pathogenic escherichia coli.

This invention relates to a traditional Chinese medicine preparation for treating infectious bursal disease (IBD), its preparation method, and its application. The preparation comprises the following components: Astragalus membranaceus 45-50 parts, Rehmannia glutinosa 30-45 parts, Isatis indigotica 25-30 parts, Isatis tinctoria 25-30 parts, Gypsum fibrosum 10-45 parts, Lonicera japonica 10-20 parts, Forsythia suspensa 10-30 parts, Taraxacum mongolicum 10-20 parts, Atractylodes macrocephala 15-20 parts, Paeonia lactiflora 15-30 parts, Lilium brownii 15 parts, Anemarrhena asphodeloides 15 parts, and Glycyrrhiza uralensis 10-30 parts. The preparation is achieved through extraction and concentration processes and is effective in treating IBD in chickens caused by both traditional infectious bursal disease virus (IBDV) and novel variant infectious bursal disease virus (nvvIBDV). This medicine significantly improves the cure rate against both traditional and variant strains, showing a particularly significant advantage in treating variant strains.

This invention provides a traditional Chinese medicine compound for treating viral myocarditis, belonging to the field of traditional Chinese medicine pharmaceutical technology. The compound consists of Forsythia suspensa, Fagopyrum dibotrys, Pseudostellaria heterophylla, Rhodiola rosea, Citrus medica, Allium macrostemon, Poria cocos, Gynostemma pentaphyllum, Salvia miltiorrhiza, Dalbergia odorifera, Cynanchum paniculatum, and Valeriana. This traditional Chinese medicine compound exhibits significant protective effects against viral myocarditis, specifically by significantly reducing damage to H9c2 cardiomyocytes caused by CVB3 virus. Its mechanism of action is closely related to downregulating the expression of inflammatory factors TNF-α and IL-6 and inhibiting the inflammatory response. Simultaneously, within the experimental concentration range, the compound shows no toxicity to cardiomyocytes, demonstrating good biocompatibility. Furthermore, this compound can significantly reduce myocardial tissue damage in a viral myocarditis model mouse by inhibiting the in vivo inflammatory response and regulating oxidative stress imbalance, providing a safe and effective new treatment option for the clinical treatment of viral myocarditis.

The invention provides a feed additive for improving transportation stress reaction of ruminants as well as a preparation method and application of the feed additive, and relates to the technical field of functional feed additives. The feed additive comprises a probiotic composition and a traditional Chinese medicine fermented material, the probiotic composition is composed of bacillus subtilis, enterococcus faecium and saccharomyces cerevisiae, and the traditional Chinese medicine fermented material is composed of codonopsis pilosula, fructus forsythiae, radix bupleuri, soybean meal and bran. The feed additive can influence the physiological indexes, biochemical indexes and blood indexes of the ruminants and promote the indexes to recover to the level before transportation, so that the transportation stress response of the ruminants is greatly improved.

The invention relates to the technical field of traditional Chinese medicines, in particular to a combustion type chronic obstructive pulmonary disease traditional Chinese medicine fumigant for targeted phlegm clearing, which is characterized in that the traditional Chinese medicine formula of the fumigant comprises platycodon grandiflorum, bulbus fritillariae cirrhosae, fructus perillae, flos farfarae, almond, radix stemonae and liquorice. The medicine effect is lasting and stable, the bulbus fritillariae cirrhosae or the green fritillary bulb is selected as a bulbus fritillariae cirrhosae source, the bulbus fritillariae cirrhosae and the green fritillary bulb have no obvious difference in phlegm clearing effect, but the bulbus fritillariae cirrhosae is slightly excellent in medicine effect durability, the medicine action time is prolonged, and the treatment effect is improved.

The application discloses a kind of clean face acne traditional Chinese medicine composition and application and gel containing the composition, it is related to clean face acne product technical field.The clean face acne traditional Chinese medicine composition of the application, including the following weight parts of raw material composition: 5-60 parts of forsythia suspensa extract, 3-50 parts of rhubarb extract, 2-50 parts of sophora flavescens extract, 5-60 parts of radix lithospermi extract, 1-25 parts of sparganium extract, 5-60 parts of herba violae extract, 3-50 parts of scutellaria baicalensis georgi extract, 2-50 parts of herba taraxaci extract, 2-50 parts of red root of tree peony extract, 1-25 parts of bletilla striata extract, 1-25 parts of mentha haplocalyx extract;Meanwhile, the gel containing the composition is disclosed.The application effectively realizes bacteriostasis for traditional Chinese medicine preparation, reduces skin inflammatory response, shortens acne subsidence time;Regulate sebaceous secretion, improve skin metabolism, accelerate the subsidence of acne;Redness average value before and after use and acne volume contrast is remarkable, and curative effect is exact.

Hippophae rhamnoides seed oil and simmondsia chinensis seed oil are used as substrates, traditional Chinese medicine ingredients such as fructus forsythiae and radix salviae miltiorrhizae are compounded, and an ultramicro homogenization process is performed. The essence oil is suitable for people with hyperplasia of mammary glands and nodules, has the effects of promoting blood circulation to remove meridian obstruction and relieving swelling and pain, has the permeability of 98% within 15 minutes, and is non-irritant.

The present invention discloses a method for identifying Ophiopogon japonicus, Forsythia suspensa and Baicalin in Qinghouyan Granules, and relates to the technical field of quality control of traditional Chinese medicine. The present invention mainly improves the method for preparing the test solution, specifically: the Ophiopogon japonicus test solution is first boiled with methanol and sodium hydroxide, and then extracted with chloroform and n-butanol; the Forsythia suspensa test solution is first boiled with calcium carbonate and water, and then evaporated with magnesium oxide, and then extracted with ethanol reflux; the Baicalin test solution is first ultrasonically treated in alkaline 50% ethanol, and then supplemented with 50% ethanol to make up for the weight loss. The present invention improves the purity and concentration of the sample to be tested by improving the preparation method of the test solution, and solves the problem that the existing technology for identifying Ophiopogon japonicus, Forsythia suspensa and Baicalin in Qinghouyan Granules has negative interference, negative tailing, and is difficult to judge.

The invention belongs to the field of veterinary drugs, and particularly relates to a probiotic fermented traditional Chinese medicine composition for preventing and controlling yellow scour of piglets and a preparation method thereof, and the probiotic fermented traditional Chinese medicine composition comprises 100 + / -2 parts of radix sophorae flavescentis, 10 + / -2 parts of fructus forsythiae, 100 + / -2 parts of liquorice, 200 + / -2 parts of dandelion, 100 + / -2 parts of coptis chinensis and 5-20 parts of bacillus velezensis SXDYYB3 preparation. The bacillus velezensis SXDYYB3 preparation is prepared by inoculating a seed solution of the bacillus velezensis SXDYYB3 into a culture medium for fermentation, the bacillus velezensis SXDYYB3 is preserved in the China Center for Type Culture Collection, and the preservation number of the bacillus velezensis SXDYYB3 is CCTCC NO: M 2025428. Two weeks before farrowing of sows, the probiotic fermented traditional Chinese medicine composition for preventing and controlling piglet yellow scour is mixed with feed to feed the sows, and the prevention effect can be achieved; after piglets are born and before yellow scour does not appear, the yellow scour of the piglets can be prevented by feeding the piglets with the medicine mixed with feed, the yellow scour of the piglets can be cured by increasing the dosage after the piglets are attacked, and the prevention and cure rate can reach 70-90%.

The invention belongs to the technical field of important compositions, and particularly relates to a traditional Chinese medicine composition for treating muscle and bone diseases, a traditional Chinese medicine preparation and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw materials: radix angelicae pubescentis, ligusticum wallichii, rhizoma sparganii, rhizoma atractylodis macrocephalae, peach kernels, radix angelicae sinensis, flos daturae, radix paeoniae rubra, radix angelicae, unprocessed radix aconiti, unprocessed radix aconiti kusnezoffii, unprocessed rhizoma pinelliae, unprocessed rhizoma arisaematis, flos carthami, unprocessed radix rehmanniae, radix et rhizoma rhei, fructus forsythiae, trogopterus dung, unprocessed radix astragali, unprocessed semen strychni, rhizoma et radix notopterygii, unprocessed radix glycyrrhizae, drynaria baronii, frankincense, myrrh and storax. Aiming at the technical problems of single effect and limited curative effect of the existing plaster, the plaster disclosed by the invention combines the functions of eliminating evil and strengthening the body resistance through scientific formula compatibility, and realizes the synergistic effect of multiple effects of clearing heat, tonifying qi, activating blood, dredging collaterals and the like, so that the treatment of the plaster is more comprehensive and deep, and the plaster has a remarkable curative effect on chronic and intractable muscle and bone diseases.

The traditional Chinese medicine composition is prepared from the following components in parts by weight: 5 to 25 parts of radix angelicae sinensis, 3 to 20 parts of rhizoma chuanxiong, 6 to 30 parts of radix salviae miltiorrhizae, 5 to 26 parts of flos carthami, 3 to 25 parts of radix paeoniae rubra, 2 to 22 parts of radix trichosanthis, 6 to 25 parts of bulbus fritillariae cirrhosae, 6 to 20 parts of frankincense, 5 to 25 parts of myrrh, 3 to 30 parts of fructus gardeniae, 3 to 26 parts of fructus forsythiae, 5 to 30 parts of flos lonicerae, 5 to 25 parts of herba violae, 5 to 30 parts of spina gleditsiae, 3 to 30 parts of caulis bambusae in taeniam, 3 to 30 parts of herba taraxaci, 5 to 25 parts of radix rehmanniae and 3 to 30 parts of radix scrophulariae. The invention provides a prescription of angelica sinensis, ligusticum wallichii, salvia miltiorrhiza, safflower, radix paeoniae rubra, radices trichosanthis, fritillaria, frankincense, myrrh, gardenia, fructus forsythiae, honeysuckle, bunge corydalis herb, spina gleditsiae, caulis bambusae in taeniam, dandelion, radix rehmanniae and radix scrophulariae, all the medicines supplement one another, the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, reducing swelling and removing stasis and cooling blood can be achieved, and the traditional Chinese medicine has a good effect on treating whelks.

The application discloses a bacillus aryabhattai FS109, named as Bacillus aryabhattai FS109, which is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC No: M 20242871. The strain can promote photosynthesis of eucommia ulmoides and forsythia suspensa, promote growth of root systems and aboveground parts, and increase content of active ingredients in medicinal parts, and has an important role in regulating growth of medicinal plants and quality of medicinal materials.

The utility model relates to the technical field of fructus forsythiae fruit picking, in particular to a fruit picking device for fructus forsythiae planting, which comprises a pair of scissor-type grips hinged with each other, semi-annular connecting blocks are fixed at one ends of the pair of scissor-type grips, arc-shaped blades are fixed on one sides of the semi-annular connecting blocks, a connecting ring frame is fixed on the lower side of one scissor-type grip, and the connecting ring frame is fixed on the lower side of the other scissor-type grip. A funnel-shaped net bag is fixed to the lower side of the connecting ring frame, and the lower end of the funnel-shaped net bag is fixedly connected with a conveying pipe. The weeping forsythia fruit picking device solves the problems that when weeping forsythia fruits are picked in the prior art, the hands of a picker are easily contaminated by juice of the weeping forsythia fruits, the weeping forsythia fruits are difficult to clean, the picker needs to continuously pick and place the weeping forsythia fruits, and the limbs of the picker are easily tired after a long time.

The present application belongs to the technical field of traditional Chinese medicine, and specifically discloses a traditional Chinese medicine composition for treating children's functional dyspepsia, a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw medicinal materials by weight: Fructus Aurantii Immaturus 5-20 parts, Magnolia officinalis 5-20 parts, Forsythia suspensa 5-30 parts, Dendrobium 5-30 parts, Atractylodes macrocephala 5-20 parts, and Glycyrrhiza 5-30 parts. The pharmacological experiment results show that the traditional Chinese medicine composition has the effects of improving gastrointestinal motility and regulating gastrointestinal hormone secretion, has a significant therapeutic effect on children's functional dyspepsia, has stable curative effect, and has a small dosage. Meanwhile, the present application has the advantages of simple process operation, low cost, good controllability and stability, and is suitable for industrialized mass production.

This invention belongs to the field of biotechnology, specifically relating to the application of the FsP4'GT protein in regulating the content of forsythosides in Forsythia suspensa. This invention discovered that the UDP-glucuronyl transferase (FsP4'GT), with an amino acid sequence as shown in SEQ ID NO:3, can catalyze the glucosylation of forsythosides to generate forsythosides. By establishing a transient expression system in Forsythia suspensa leaves, it was found that overexpression of FsP4'GT significantly increased the yield of forsythosides. Furthermore, co-expression of FsE4MT01 or FsE4MT02 with FsP4'GT in the closely related species Forsythia suspensa also significantly enhanced the synthesis of forsythosides. This invention elucidates the key terminal steps in the biosynthesis of forsythosides, providing a strategic basis for increasing the yield of this medicinally valuable compound through metabolic engineering.