56 results about "Organ protection" patented technology

A system for perfusing a localized site within a body includes a catheter assembly having a venous access line that is adapted to deliver perfusate to the localized site, a venous or arterial drainage line adapted to drain perfusate from the localized site, and an occlusion device adapted to prevent some or substantially all physiological blood flow between the localized site and the systemic circulation of the body during and in the course of perfusing and draining perfusate to and from the localized site. The system may include a blood circuit associated with the catheter assembly to facilitate blood conditioning for use as the perfusate, in the course of a controlled perfusion and/or drainage of untreated, treated, or inactivated treated blood to and from the localized site. A delivery machine may control the blood circuit and catheter assembly in order to both deliver perfusate to, and drain some or all perfusate from, the localized site in a manner that provides perfusate to substantially only the localized site.

The device claimed refers to means for human respiration organ protection against dust-like particles - in particular, against allergen-carrying particles. It may be used as a nasal filter, as a filter in respirators, and so forth. The device comprises a hollow body having one or several inlet channels and one outlet orifice that are intended for the passage of inhaled air, with the inner surface of said body having such a shape that is close to the shape of a truncated cone, and said inlet channels are made in the major base of the cone with the direction of the axis of each of the channels being combined out of the tangential component and axial component, while the outlet orifice is made in the vertex (minor base) of the cone, and the inner body surface is covered with a sticky substance capable of retaining dust and allergen particles contained in the inhaled air.

This application describes compositions, methods of treatment, and methods of manufacturing a medicament for reducing injury or damage to cells, tissues or organs during ischemia, reperfusion, or following ischemia or trauma. The methods for reducing damage to a cell, tissue or organ comprise administering an effective amount of a composition including (i) a potassium channel opener or agonist and/or adenosine receptor agonist; and (ii) an antiarrhythmic agent. The methods may further include postconditioning the cell, tissue or organ.

The present invention includes a method for the treatment of myeloma comprising identifying a patient with myeloma and administering to the patient a synergistic, effective amount of a truncated, dominant negative form of Galectin-3 and a proteasome inhibitor.

The present invention concerns protection of an organ or tissue following an ischemic episode In particular aspects, the invention concerns organ preservation for transplantation, angina pectoris, kidney reperfusion injury, and so forth In specific embodiments, the organ is subjected to an inhibitor of an NCCa-ATP channel that is regulated by SUR1 Exemplary inhibitors include sulfonylurea compounds, such as glibenclamide, for example

The invention discloses leukocyte-depleted warm blood cardioplegic solution perfusion device, which is mainly used for the perfusion of a cardioplegic solution to the heart during open heart surgery under cardiopulmonary bypass and is also used for the perfusion of a tissue and organ protection solution. A perfusion bag is made from four layers of thin films, wherein by virtue of the four layers of the thin films, the perfusion bag is divided into a temperature regulating cavity, a medicine liquid cavity and a pressurizing cavity from left to right; a temperature regulating liquid injection tube for injecting temperature regulating liquid is arranged on the upper part of the temperature regulating cavity, and a temperature regulating liquid drainage tube for draining the temperature regulating liquid is arranged on the lower part of the temperature regulating cavity; a medicine liquid injection tube which is communicated with the medicine liquid cavity is arranged on the upper part of the medicine liquid cavity; a pressurizing and inflating tube which is communicated with the pressurizing cavity is arranged on the lower part of the pressurizing cavity; and a perfusion tube which is communicated with the medicine liquid cavity is arranged on the lower part of the medicine liquid cavity. The cardioplegic solution perfusion device disclosed by the invention has the beneficial effects that the heat of the cardioplegic solution can be preserved or increased at any time; and when the cardioplegic solution is inflated and pressurized, the perfusion device can be used for preventing air from entering the cardioplegic solution and for removing residual liquid in the perfusion bag to the greatest extent.

The invention discloses an ice-temperature organ protection solution. A sterilizing aqueous solution is prepared from potassium citrate, sodium citrate, magnesium sulfate, mannitol, 6-aminoadenine phosphate, astragalus membranaceus and water for injection by mixing. Every 100ml of the ice-temperature organ protection solution comprises 0.87-1.16g of potassium citrate, 0.98-1.19g of sodium citrate, 1.02-1.15g of magnesium sulfate, 5.56-6.85g of mannitol and 0.45g of 6-aminoadenine phosphate and 5ml of astragalus membranaceus extract. The ice-temperature organ protection solution is prepared by mixing the potassium citrate, the sodium citrate, the magnesium sulfate, the mannitol, the 6-aminoadenine phosphate and the astragalus membranaceus, and adding the water for injection into a 100ml bottle to dilute the volume to 100ml. Because the proportion of the mannitol is increased, the phase-transition temperature point of the ice-temperature organ protection solution can be decreased, and the ice-temperature organ protection solution is more suitable for preserving an organ at ice temperature. The added astragalus membranaceus has the functions of resisting the oxidative damage and promoting the activity of a Na<+>-K<+>-ATP enzyme. The ice-temperature organ protection solution has low viscosity and a good perfusion effect and can decrease the temperature of an organ rapidly in a short time.

The invention discloses a heat isolation organ protection cover for a 3D printer. The problem about heat isolation protection between a current 3D printer high-temperature cavity and a motion component is solved. A plurality of waveform heat isolation layers are included. Each heat isolation layer is connected with the adjacent heat isolation layer at the position of the wave crest or the trough.After the organ protection cover is stretched, a hollow structure is formed between every two adjacent heat isolation layers. Through the hollow structures between the heat isolation layers and isolation of the multiple heat isolation layers, the heat conductivity between an upper face and a lower face of the organ protection cover is greatly reduced, good heat isolation and heat preservation performance of the heat isolation organ protection cover is achieved, and accordingly the problem about heat isolation protection between the 3D printer high-temperature cavity and the motion component issolved.

A method of providing anesthesia and organ-protection to a subject in need thereof comprises co-administering to the subject a non-anesthetic protective gas in an amount effect to provide organ protection, and a liquid anesthetic agent in an amount effective to provide anesthesia, at normobaric conditions.

The present invention discloses a new polypeptide having a tissue protective activity. The present invention discloses a sequence, a structure and a preparation method of the polypeptide. The polypeptide has a good tissue and organ protection effect, especially provides good cure effects for inflammations of a plurality of tissues, and has characteristics of no toxicity, safety, and wide medicinal and medical application prospects.

The invention discloses a juvenile penaeus vannamei temporary rearing special feed formula and a use method thereof. The formula comprises the following main components of viable bacteria, organic acid, enzyme, trace metabolites, immunoenhancement substances, organ protection substances, energy supply substances and vitamins. A specific preparation process comprises the following steps of S1, performing superfine grinding, specifically putting 100 parts of organic acid, enzyme, trace metabolites, immunoenhancement substances, organ protection substances, energy supply substances and a vitamin mixture A into a ball mill, and performing superfine grinding to obtain a mixture B; According to the juvenile penaeus vannamei temporary rearing special feed formula and the use method thereof, through the treatment of activity retention technologies such as superfine grinding, high-temperature inactivation, aerobic and anaerobic multi-time alternate fermentation, deep kneading slow mixing, low-temperature granulation and positive-pressure anaerobic packaging, the characteristics that granular feed is low in scatter ratio in water, comprehensive in single granule nutrition, capable of conforming to the feeding habit of prawns, convenient in feeding, and the like are achieved, and the functional substance richness and the application effectiveness of a product are guaranteed.

An organ protectant solution which is intravenously administered includes a high concentration of cell-impermeant molecules and at least one oncotic agent. The cell-impermeant molecules preferentially load into the interstitial space and the oncotic agent(s) is/are restricted to the vasculature space. Together, they promote transfer of water from cells to interstitium and into the capillaries, thereby preventing or reducing cell swelling, and maintaining blood circulation and oxygenation of tissues. The organ protectant solution extends the “Golden Hour” for traumatic and/or hemorrhagic shock patients, thereby allowing more time for those patients to reach a point of care facility to receive medical treatment.

The invention discloses a crown block type graphite machining tool. The tool comprises a body, a first automatic door, a dust exhaust device, a cutter driving device and an organ protection cover, wherein the body is provided with an inner cavity, the top surface and one side surface of which are opened; a dust discharging opening and a worktable for machining graphite materials are arranged at the bottom of the inner cavity; an air inlet is formed in the side wall of the inner cavity; the first automatic door is arranged at the open side surface of the inner cavity, is used for ingression andegression of materials and a cutter, and comprises a first door body and a first door body driving mechanism for driving the first door body to be open and closed; the dust exhaust device is used forcollecting graphite dust and comprises a dust exhaust pipeline connected with the dust discharging opening; the cutter driving device is arranged at the top of the body, is used for clamping the cutter and driving the cuter to machining the graphite materials, and comprises an X-axis driving mechanism, a Y-axis driving mechanism and a Z-axis driving mechanism; and the organ protection cover is paved at the open top of the body. The crown block type graphite machining tool has the effects of improving the protection effect and keeping relatively high machining precision.

The invention discloses multifunctional organ protection equipment for radiotherapy. The equipment comprises a bottom plate, wherein a cross beam is arranged below the bottom plate, pressing-type rollers with self-locking devices are arranged at four right angles of the bottom plate, lifting cylinders which can be finely adjusted are arranged at four right angles above the bottom plate, and pistons of the lifting cylinders are fixedly connected with the bottom plate. A supporting plate is fixedly arranged on the outer wall of a cylinder body of the lifting air cylinder, two sides of the long edge of the supporting plate are fixedly connected with a first U-shaped protective material plate, the first U-shaped protective material plate, a second U-shaped protective material plate and a thirdU-shaped protective material plate are movable anti-radiation shielding plates, and other structural materials are carbon fiber materials. Lifting and moving adjustment of the protection bed can be achieved, the application range is wide, adjustment can be performed at any time according to different treatment environments, the protection capacity is high, important organ parts except the radiotherapy part of a patient can be effectively protected on the premise that the radiotherapy position is accurate, scattered rays are prevented from directly irradiating important organs, and the protection effect is good.

The invention relates to isolated organ protection liquid. The protection liquid takes water as a solvent and is prepared from the following components with the mass concentration or the mol concentration: a cell swelling inhibitor with the concentration of 0.8 to 1.6g/L, a cell membrane stabilizing agent with the concentration of 0.01 to 0.015g/L, adenosine with the concentration of 0.005 to 0.008mol/L, allopurinol with the concentration of 0.001 to 0.002mol/L, glutathione with the concentration of 0.001 to 0.005mol/L, an H<+> buffering agent with the concentration of 0.1 to 0.12mol/L and magnesium sulfate with the concentration of 0.003 to 0.006mol/L, wherein the cell swelling inhibitor is prepared from polyvinyl alcohol, potassium hydroxide and sodium hydroxide. Compared with the priorart, the solution viscosity is reduced, a cell membrane is protected and the production cost is reduced.