6 results about "Organ protection" patented technology

The application discloses a plant extraction compound for reducing blood pressure, a preparation method and application thereof. The compound is composed of high-purity silybin extract and a specific fusion polypeptide through molecular self-assembly. The sequence of the fusion polypeptide is shown in sequence SEQ ID NO:1, which innovatively integrates cell membrane penetration function, angiotensin II receptor 1 antagonism function and hydrophobic drug binding function. The core of the application is that through polypeptide-mediated active targeting, silybin is accurately delivered to the diseased blood vessel area, and the double synergistic mechanism of upstream ACE inhibition and downstream receptor blocking of the renin-angiotensin-aldosterone system is realized. In-vivo pharmacodynamic experiments prove that compared with single components, the compound can produce more significant and persistent antihypertensive effect, and can effectively reverse myocardial hypertrophy and fibrosis caused by hypertension, and show excellent synergistic therapeutic effect and target organ protection ability.

This application discloses a method, system, device, and medium for perfusion control of ex vivo organs, relating to the field of ex vivo organ protection and intelligent control technology. The method includes: constructing an extended state vector based on hemodynamic state variables within multiple consecutive control cycles; using a prediction model to determine a predicted output vector based on the extended state vector and a set perfusion flow control sequence; using an optimization function to determine a perfusion flow control sequence based on the predicted output vector, a reference vector, and the set perfusion flow control sequence; perfusing the ex vivo organ based on the perfusion flow control sequence; obtaining the actual value of the cycle-equivalent perfusion pressure after perfusion; updating the prediction model based on the actual value and predicted value of the cycle-equivalent perfusion pressure; and returning to the step of using the prediction model to determine the predicted output vector based on the extended state vector and the set perfusion flow control sequence. This application enables closed-loop control of ex vivo organ perfusion.

This utility model discloses a novel long-distance bellows cover guide rail, including a main mounting assembly, a main support assembly disposed on the rear side of the main mounting assembly, an upper guide assembly disposed on the main support assembly, and a lower guide assembly disposed on the main mounting assembly. A protective assembly is connected to the upper guide assembly and the lower guide assembly via a wear-resistant component. The beneficial effects of this utility model are that the guide rail of this technical solution has an ingenious structural design, strong practicality, and stable operation. Using this guide rail effectively ensures the stability and smoothness of the protective cover's movement, while avoiding the use of machine tool guide rails and effectively preventing wear on machine tool guide rails.

A balloon catheter, comprising an elongate body having a proximal end and a proximal opening, a distal end and a distal opening, the proximal and distal openings defining an inner lumen therebetween, wherein the body defines an inner surface and an outer surface, a first internal channel positioned within the inner lumen and fluidly connected to at least one balloon positioned on the outer surface of the body at the distal end, wherein the balloon is configurable between an inflated state and a deflated state, and a second internal channel positioned within the inner lumen.

The application belongs to the technical field of veterinary antibacterial drugs, and provides application of LUT combined with FF in preparation of a drug for treating duck Riemerella anatipestifer infection. The application uses luteolin (LUT) in a sub-inhibitory concentration in combination with florfenicol (FF), which can significantly reduce the MIC value of florfeniol to duck Riemerella anatipestifer, greatly reduce the dosage of florfenicol, reduce the risk of drug residues and breeding costs, avoid the generation of drug resistance caused by the single use of florfenicol, and prolong the clinical service life of florfenicol; the bactericidal effect is enhanced, the application has significant anti-inflammatory and organ protection effects, high safety, is not prone to drug resistance, and has a wide application prospect.

The utility model discloses a high -speed machine roof structure of servo motor drive, include: organ protection folding leaf, support beam and two groups of linear module, organ protection folding leaf one end connects lathe, the other end connects support beam, two groups of linear module are connected two ends of support beam respectively, and two groups of linear module synchronous drive support beam along organ protection folding leaf extension and folding direction movement, linear module includes: motor, speed reducer and transmission assembly, and transmission assembly includes first transmission part and second transmission part, and first transmission part sets up in the end of support beam, and second transmission part sets up on lathe, and motor is through speed reducer drive first transmission part relative to second transmission part along linear motion, and then first transmission part drives support beam and moves, the utility model discloses through the motor of control two groups of linear module realizes the synchronous movement of two ends of support beam to avoid the problem that the out -of -sync and the lag of easy appearance under the condition of larger span, and then reduce the difficulty of installation debugging.