73 results about "Pancreatic juice" patented technology

The invention provides a duodenal internal covering membrane, which is made of degradable shape memory biocompatible material and relates to degradable medical equipment internally installed in a digestive tract. After the internal covering membrane is implanted into a duodenum, chyme can be split from bile and pancreatic juice, so stomach exudates are prevented from being directly digested, absorbed and metabolized in the duodenum, and the histocompatibility is good; after being implanted into a human body, the duodenal internal covering membrane is steady, is not easy to slide off to be incarcerated and can be gradually degraded in the human body after 2 months to 5 years, so complicated operation and the injury to organs and tissue, which are caused when the duodenal internal covering membrane is removed from the human body in the future, are avoided, a rebound effect achieved after the original barrier is instantaneously and thoroughly dismounted can be slowed down, and the duodenal internal covering membrane can be prepared into medical equipment which is used for curing obesity and diabetes mellitus and does not need to be removed from the human body in the future; and tube-shaped part sinking induced by gastrointestinal motility and jejunum content backflow caused by the decrease of a gap between a tube-shaped part of the internal covering membrane and the inner wall of the duodenum can be avoided. The prepared medical equipment for curing the obesity and the diabetes mellitus can achieve the effects of dropping prevention, removal exemption, rebound inhibition and injury reduction.

The invention discloses an integrated bile and pancreatic juice drainage pipe which comprises a water sac type bile outer drainage pipe and a pancreatic juice inner drainage pipe. The water sac type bile outer drainage pipe comprises a drainage pipe section I, a drainage pipe section II and a drainage pipe section III which are communicated in sequence. The outer wall of the drainage pipe section II is sleeved with a balloon thin film. The pancreatic juice inner drainage pipe comprises a drainage pipe body, a pipe cap and a drainage pipe tail portion. The end, far away from the drainage pipe section II, of the drainage pipe section III is matched with the drainage pipe tail portion. The integrated bile and pancreatic juice drainage pipe has strong tension force, can have the function of avoiding disengagement of the water sac type bile outer drainage pipe, is suitable for bile ducts of various diameters, has no damage to bile duct mucosa, duodenal papillae and upper gastrointestinal tract mucosa, and cannot cause obstruction of biliary tracts while avoiding displacement of the water sac type bile outer drainage pipe. The pancreatic juice inner drainage pipe is connected with the water sac type bile outer drainage pipe through a line, and the function of avoiding displacement or disengagement of the pancreatic juice inner drainage pipe is achieved.

Provided herein is technology relating to isolating and/or extracting DNA from gastric fluid samples, e.g., pancreatic juice samples. In particular, the technology relates to methods, reagents, and kits for isolating DNA from stimulated pancreatic juice samples, for use, e.g., in methylation and mutation analyses.

Disclosed herein is a stent implanted in the body of a patient. The stent includes a hollow cylindrical stent body which is made of a super-elastic shape memory alloy and has an expanded diameter part on one end thereof, and a support stent which has an elastic spherical structure and is fitted over the cylindrical stent body behind the expanded diameter part. The stent is implanted in the body such that food that has passed through the stomach is prevented from mixing with bile or pancreatic juice in the duodenum and moves directly into the small intestine to prevent the duodenum from absorbing nutrients of the food while the small intestine directly digests the food and absorbs the nutrients, thus minimizing a nutrient absorption rate, thereby preventing the obesity of the patient.

The invention discloses a bile and pancreatic juice drainage tube which comprises a loop type bile external drainage tube and a pancreatic juice internal drainage tube. The loop type bile external drainage tube comprises a straight tube, an elastic loop pipe I and an elastic loop pipe II which are connected in sequence, wherein the elastic loop pipe I and the elastic loop pipe II are in the shapes of Archimedean curves one the whole. The pancreatic juice internal drainage tube comprises a drainage tube body and a tube cap located at the upper end of the drainage tube body, and a line II is arranged on the drainage tube body and penetrates through the side wall of the straight tube and extends in a tube cavity of the straight tube. The bile and pancreatic juice drainage tube reduces the probability of slipping of the loop type bile external drainage tube, does not stimulate bile duct mucosae, duodenal papilla, gastrointestinal mucosae and throat mucosae, and has an effect of preventing the pancreatic juice internal drainage tube from dislocating or escaping.

The invention discloses a pancreatic juice developer, and a preparation method and an application thereof. The pancreatic juice developer comprises 0.03-0.70g/L of bromothymol blue sodium salt, 0.03-0.70g/L of phenol red sodium salt and 1.23-11.76g/L of sodium bisulfate monobydrate. Compared with pancreatic juice developers in the prior art, the pancreatic juice developer has the advantages of high chromogenic sensitivity and obvious color contrast in the intraoperative seepage detection process. The pancreatic juice developer can flexibly realize pancreatic juice visualization in the intraoperative and postoperative processes according to concrete demands by preparing different dosage forms and selecting carriers in order to accurately realize qualitative diagnosis and intraoperative positioning diagnosis of pancreatic fistula.

The invention discloses a loop-type bile and pancreatic juice drainage tube, which comprises a loop-type bile drainage tube and a pancreatic juice drainage tube, wherein the loop-type bile drainage tube comprises a straight tube and an elastic loop tube; the elastic loop tube is integrally of a cylindrical spiral line shape and is provided with an elastic loop tube head and an elastic loop tube tail; the pancreatic juice drainage tube comprises a drainage tube body and a drainage tube tail positioned on the lower end of the drainage tube body; the pancreatic juice drainage tube also comprises a second line, wherein one end of the second line is connected with the lower-end side wall of the drainage tube body, and the other end of the second line passes through the drainage tube tail to be connected with a coil or a metal ring. According to the loop-type bile and pancreatic juice drainage tube, the slippage probability of the loop-type bile drainage tube is lowered, and the loop-type bile and pancreatic juice drainage tube does not irradiate a bile duct mucous membrane, duodenal papilla, gastrointestinal mucosa and a throat mucous membrane; while the loop-type bile drainage tube is taken out, the pancreatic juice drainage tube can be simultaneously taken out so as to avoid a secondary ERCP (Endoscopic Retrograde Cholangiopancreatography) surgery and lower treatment cost and surgery risks; the loop-type bile and pancreatic juice drainage tube has a function that the pancreatic juice drainage tube can be prevented from inwards moving or separating.

A pancreatic disease is tested for with high sensitivity even with simple equipment and a simple procedure. Provided is a method of detecting pancreatic disease including detecting a concentration of S100P in at least one of a pancreatic juice and a body fluid containing pancreatic juice collected from a test subject by immunochromatography. Additionally provided is a pancreas testing kit including an immunochromatography device that holds an anti-S100P antibody and a collection vessel that retains a protease inhibitor that inhibits an activity of a protease contained in the pancreatic juice.

The invention discloses an integrated drainage tube for pancreatic duct supporting and drainage and peripancreatic drainage. The integrated drainage tube comprises a bile and intestinal juice drainage tube, a pancreatic juice drainage tube and a breather tube, wherein the bile and intestinal juice drainage tube comprises an drainage body inner tube, a drainage connection tube and a drainage body outer tube which are connected to form a whole, the pancreatic juice drainage tube comprises a pancreatic juice drainage body inner tube, a pancreatic juice drainage connection tube and a pancreatic juice drainage body outer tube which are connected to form a whole, the drainage body inner tube and the pancreatic juice drainage body inner tube form a cross structure, and the breather tube comprises a breather inner tube, a breather connection tube and a breather body outer tube which are connected to form a whole. The integrated drainage tube can timely drain intestinal juice, bile and other liquid accumulated around a pancreatico-duodenal anastomotic stoma, or even can also perform timely drainage once pancreatic juice is leaked, so that no liquid is accumulated besides the pancreatico-duodenal anastomotic stoma, and good conditions are provided for the pancreas and intestine to anastomoseas early as possible.

The invention relates to a Model Gut System (MGS) comprising a pancreatic phase consisting essentially of synthetic pancreatic juice comprising pancreatin and one or more suitable pancreatic diluent(s) at a pH from about 7 to about 9, preferably about 7.9 to about 8.2, and porcine bile.

Provided is a method for detecting a target particle in a biosample containing pancreatic juice, the method enabling the detection in a solution that has a lower concentration or number density of the target particles than the level possible for conventional photoanalysis techniques. This method comprises: a probe-binding step for preparing a sample solution, which contains a biosample containing pancreatic juice and a fluorescent probe capable of binding to a target particle, and binding the fluorescent probe to the target particle in the biosample; and a calculation step for calculating the number of molecules of the target particles bound to the fluorescent probes by the scanning molecule counting method. A light emission property of emitted light is different between a state where the fluorescent probe is bound to the target particle and a state where the fluorescent probe is present alone. In a state where the fluorescent probe is bound to the target particle, the fluorescent probe emits fluorescence having a wavelength of 600 nm or longer.

The invention provides a method, including placing first and second electrodes (90) at respective first and second sites of a duodenum (40) of a subject, and activating the electrodes (90) to increase a blood insulin level of the subject. Other embodiments are also described.

The invention relates to a developing type degradable restoration pancreatic duct bracket, which is prepared from the following ingredients including 50 to 100 weight parts of degradable medical materials A, 0.1 to 50 weight parts of heeling restoration materials B, 0.001 to 0.05 weight part of developing agents C, 0.001 to 0.05 weight part of pancreatitis treating medicine D, or 0.001 to 0.05 weight part of antitumor medicine E. The developing type degradable restoration pancreatic duct bracket has the advantages that the biocompatibility is high; the form and the position of implanting materials can be fast judged; the degrading time is controllable; and in the complicated pancreatic duct rebuilding process, the effects of pressure reduction support, drainage, pancreatic duct heeling facilitation, convenience in pancreatic juice condition observation, postoperative pancreatic ductograph and the like can be achieved.

The invention discloses a slow-release stress-resistant probiotic crystal ball and a preparation method thereof. The slow-release stress-resistant probiotic crystal ball comprises a probiotic inner core layer, a slow-release layer, a stress-resistant layer and a protective layer which are sequentially arranged from inside to outside, wherein the probiotic inner core layer is of a spherical structure, and the surface of the probiotic inner core layer is sequentially coated with the slow-release layer, the stress-resistant layer and the protective layer. The probiotic inner core layer is wrapped with the material of the slow-release layer, the material of the stress-resistant layer and the material of the protective layer in sequence through a pot coating method to obtain the slow-release stress-resistant probiotic crystal ball. The probiotic crystal ball membrane material with better stress resistance is prepared, and the stress-resistant membrane can better protect the probiotics in the membrane, so that the probiotics are prevented from being damaged and inactivated by gastric acid, cholate, pancreatic juice and the like in the digestive tract during use, and an ideal effect is exerted.

The invention discloses a Chinese herbal medicine goat feeding promoting agent which comprises the following raw material components by weight: 10-15 parts of orange peel, 10-15 parts of hawthorn, 5-10 parts of semen strychni, 10-15 parts of Lysimachia sikokiana, 5-10 parts of areca, 1-5 parts of amomum, 5-10 parts of fennel, 10-15 parts of sesame and 5-10 parts of Ferula asafoetida; the Chinese herbal medicine goat feeding promoting agent is prepared from Chinese herbal medicines with the effect of promoting appetite, tonifying spleen, strengthening spleen and benefiting qi and mild stimulation effect on intestines and stomach as main raw materials, and the Chinese herbal medicine goat feeding promoting agent can promote the secretion of digestive juice, has the effect of eliminating intestinal pneumatosis, helping digestion, guiding qi, normalizing spleen and stomach operation, improving appetite, increasing feed intake, promoting the secretion of large amount of saliva, gastric juice, pancreatic juice and bile, exciting gastrointestinal smooth muscle, accelerating gastrointestinal peristalsis and accelerating the absorption speed of nutrients, has antibacterial and antimicrobial effect, can improve the body specific and non-specific immunity, reduces the incidence of diseases, and is anti-stress. The Chinese herbal medicine goat feeding promoting agent is wide in source, low in cost, rich in minerals and vitamins, has the effect of disease resistance and stress resistance, and improves production efficiency.

The invention discloses high-effect pig starter feed containing a tobacco straw extract. The high-effect pig starter feed is prepared from basic rations, the tobacco straw extract and an oxytetracycline calcium premix, the additive amount of the tobacco straw extract is 200 mg/kg, and the additive amount of the oxytetracycline calcium premix is 200 mg/kg, wherein the main component of the tobaccostraw extract is xylobiose obtained through alkaline extraction and enzymolysis treatment. The tobacco straw extract, namely the xylobiose, is added into the pig starter feed, the xylobiose cannot bedegraded by saliva, gastric juice, pancreatic juice and intestinal juice and thus is the most stable oligosaccharide in the whole digestive system, thus by adding the xylobiose into the pig starter feed, the diarrhea rate of pig starters can be effectively decreased, the utilization rate of the feed and the survival rate are increased, growth and development of the pig starters are promoted, meanwhile the xylobiose is used in combination with the oxytetracycline calcium premix , the xylobiose and the oxytetracycline calcium premix have the synergistic effect, thus the anti-diarrhea property and the growth-promoting property of the pig starter feed can be further improved, and the high-effect pig starter feed is obtained and has wide application prospects.

The invention provides a pancreas and intestine anastomat. The pancreas and intestine anastomat comprises a slender rod, an anastomosis cap, a through hole and a pancreatic juice hole, wherein the anastomosis cap is fixed on the slender rod, the slender rod is of a hollow structure with the through hole, and the pancreatic juice hole is formed in one end of the slender rod. The invention provides a novel pancreas-intestine/stomach anastomosis method and apparatus. The method and the apparatus can change a conventional method of suturing pancreas and stomach and intestine with sutures, the pancreas and intestine anastomat has the functions of reconstructing a passage for pancreatic juice to enter a digestive tract, preventing the pancreatic juice from leaking and conveniently connecting and anastomosing the stomach and intestines and a pancreatic juice stump, no sutures are needed, and the anastomosis is convenient and firm.

The invention belongs to the fields of biomedicine and high polymer material, and relates to a radioactive bracket for treating malignant tumor of digestive tract and the preparation method thereof. The bracket combines the radionuclide with the molecular surface of a degradable material, so as to produce radioactive biodegradation brackets of different concentrations for treating malignant tumor of digestive tract; the radioactive bracket for treating malignant tumor of digestive tract consists of a digestive tract bracket, an inner layer, an outer layer and positioning tube sleeves; the digestive tract bracket is coated with the inner layer, bilateral sides of the inner layer are provided with the positioning tube sleeves, and the outer layer wraps the inner layer and the positioning tube sleeves, wherein the inner layer is prepared by the mixture of a biocompatible high polymer material and a radioactive substance, the outer layer is a biocompatible high polymer material, and the positioning tube sleeves are made of stainless steel. The bracket can not only ensure the effective drainage of bile and pancreatic juice, but also treat the tumor with the locally precise radiotherapy effect; the bracket is safe, reliable, low cost, simple in preparation method, strong in practicability, and favorable application prospect.