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Surgical seam of yamamai silk and preparation thereof

A technology of surgical operation and silkworm silk, which is applied in the field of surgical suture and its preparation, can solve the problems of poor absorbability, etc., and achieve the effect of easy knotting, good tolerance, and smooth thread

Inactive Publication Date: 2008-08-20
深圳前海南岭天蚕科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

General surgical thread is a product derived from silk, but due to the requirements of the production process, its absorbability in human tissue is poor

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] (1) Soak the silkworm silk in the aqueous solution containing 0.2wt% sodium silicate, 0.1wt% pepinga, and 0.02wt% sulfonated castor oil for 18 minutes; Twisting into required specification wire blank; (3) Apply silkworm sericin on the wire blank; (4) Heating to 90°C to set the shape.

[0017] The animal anastomosis experiment in a hospital in Hunan Province shows that the suture has high strength, smooth thread, easy to knot (50% less knotting than sheep catgut), and fast absorption (absorption time is 50% shorter than sheep catgut) ; It is used for nerve anastomosis, which can promote the regeneration of anastomotic nerve.

Embodiment 2

[0019] (1) Soak the silkworm silk in the aqueous solution containing 0.3wt% sodium silicate, 0.2wt% pepinga, and 0.03wt% sulfonated castor oil for 15 minutes; Twisting into required specification wire billets; (3) applying silkworm sericin on the wire billets; (4) heating to 100°C to set the shape. Reprocessed into needle sutures and non-needle sutures.

[0020] Experiments on animal vascular anastomosis at the 163 Hospital of the People's Liberation Army show that the suture has high strength, smooth thread, easy knotting (40% less knotting than sheep catgut), and fast absorption (absorption time is 45% shorter than sheep catgut); It is used for nerve anastomosis and can promote the regeneration of anastomotic nerve.

Embodiment 3

[0022] (1) Soak the silkworm silk in the aqueous solution containing 0.1wt% sodium silicate, 0.1wt% pepina, and 0.01wt% sulfonated castor oil for 20 minutes; Twisting into required specification wire billets; (3) applying silkworm sericin on the wire billets; (4) heating to 80°C for setting. Reprocessed into needle sutures and non-needle sutures.

[0023] An anastomosis experiment on animals in a hospital in Hunan Province shows that the suture has high strength, smooth thread, easy to knot (50% less knotting than sheep catgut), and fast absorption (absorption time is 42% shorter than sheep catgut) ; It is used for nerve anastomosis, which can promote the regeneration of anastomotic nerve.

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PUM

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Abstract

The invention relates to wild silk surgical operation suture thread and the preparation method. The wild silk yarn surgical operation suture thread adopts wild silk woven or twisting thread as thread rod and the surface is covered by wild sericin. The preparation method comprises the following steps: (1) place and immerse the wild silk into the aqueous solution, which comprises 0.1-0.3wt% sodium salt, 0.1-0.2wt% surface-active agent and 0.01-0.03wt% penetrating agent for 15 to 20 minutes; (2) after fish out and dry the wild silk, use machine to weave and twist the wild silk into the thread rod with required specification; (3) apply the wild sericin on the thread rod; and (4) heat up the silk for forming and the heating temperature should be controlled between 80 to 100 degrees centigrade. The suture thread has the advantages of high strength, smooth thread, easy knotting, good absorbing performance, good pancreatic juice and bile tolerance, easy dialyneury and capability of promotion of nerve regeneration.

Description

technical field [0001] The invention relates to a surgical suture and a preparation method thereof, in particular to a human body absorbable surgical suture and a preparation method thereof. Background technique [0002] According to the biodegradability of surgical sutures, they can be divided into two categories: non-absorbable sutures and human absorbable sutures. Non-absorbable sutures do not degrade in the body, foreign matter remains in the body, and granulation is easy to form, which is a hidden danger to the human body. Therefore, the sutures must be removed, which not only adds trouble to the doctor, but also brings pain to the patient. The other is absorbable sutures, which can be degraded into soluble substances in the body, absorbed by the body, and usually disappear from the implantation site within 2-6 months. [0003] Generally speaking, an ideal absorbable suture should have four basic requirements: (1) predictable absorbability; (2...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L17/10D02G3/02D01C3/00D06M11/79D06M13/256D06M101/10
Inventor 曹成书李树根
Owner 深圳前海南岭天蚕科技有限公司
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