24 results about "Absorbable suture" patented technology

The invention relates to the technical field of biological materials, and provides an absorbable self-repairing suture line for maintaining the stability of a mechanical biological microenvironment and a preparation method of the absorbable self-repairing suture line. According to the suture line, an absorbable high polymer material is adopted as a matrix, and PLA microcapsules containing a medical-grade cyanoacrylate n-octyl ester repairing agent are uniformly dispersed in the matrix through a melt blending spinning process. When the suture line generates microcracks at dynamic tissue parts such as cardiovascular and digestive tracts due to periodic stress, the stress at the tip of the cracks enables the microcapsules to be broken to release the repairing agent, rapid in-situ polymerization occurs under triggering of tissue fluid, the self-repairing efficiency of 90% or above is achieved, and the strength retention rate of 95% or above is maintained in the key rehabilitation period of the suture line. The defect that a traditional absorbable suture line is prone to fatigue fracture in a dynamic environment is overcome, the mechanical integrity is actively maintained through an intelligent self-repairing mechanism, all components can be completely degraded and absorbed, and a safer and more reliable solution is provided for dynamic tissue repairing.

The application relates to the technical field of medical suture materials, and particularly discloses a non-absorbable suture with tissue self-adaptive performance, which comprises a core layer, a transition layer and an outer layer; the core layer and the transition layer are fixed through hot melt adhesion, and the outer layer is coated on the surface of the transition layer through electrostatic spinning; the core layer is a polyether ether ketone fiber with a diameter of 50-100 mu m and a tensile modulus of greater than or equal to 3 Gpa; the transition layer is a nickel-titanium alloy wire braided net with a thickness of 40-60 mu m, and the wire diameter of the nickel-titanium alloy wire is 20-30 mu m; and the outer layer is a poly-lactic acid-glycolic acid copolymer coating layer containing nano-hydroxyapatite with a thickness of 30-50 mu m; and the application further provides a preparation method of the non-absorbable suture. The non-absorbable suture has the advantages of tissue self-adaptive performance, persistent mechanical support and bioactivity, can effectively avoid tissue cutting, abrasion and suture loosening, and can reduce the incidence of postoperative complications such as inflammation and pain.

1. A surgical kit for performing surgery for the treatment of reflux disease, the surgical kit comprising the following components: An implantable motion restriction device configured to impede movement of the lower esophageal sphincter relative to the thoracic diaphragm, the device having at least a portion positioned between the angle of His and the thoracic diaphragm; a lubricant including an antimicrobial agent for use in combination with the implantable motion restriction device; and at least one absorbable suture.

The invention belongs to the technical field of medical instruments, and particularly relates to an absorbable suture and a preparation method and application thereof. Two coatings are loaded, from inside to outside, the first coating is the rapamycin coating with the anti-scar effect, the second coating is the artemisinin coating with the antibacterial and anti-inflammatory effects, and stable loading and slow release of the rapamycin medicine and the artemisinin are achieved through the structure of the two coatings. The suture can release artemisinin in the surgical suture incision inflammation period, infection is prevented, and inflammatory response is reduced. The rapamycin is released in a surgical suture incision scar proliferation period, so that scar proliferation of a surgical incision is prevented and reduced.

The utility model discloses a kind of absorbable suture coating devices, it is related to suture technical field, including connecting frame, it further includes placing frame, auxiliary wheel, transmission rod, transmission motor, threaded rod, threaded tube, moving frame, mounting bracket, reinforcing plate, lower press roll and control mechanism, placing frame is installed in the inside of connecting frame, auxiliary wheel is rotatably connected in placing frame, two groups of transmission rod are rotatably connected in connecting frame, transmission motor is installed on the upper surface of connecting frame, the output end of transmission motor is arranged in the transmission rod top end located at top, threaded rod is installed in transmission rod inner end, threaded tube is screw-connected on the outer surface of threaded rod, moving frame is installed on the outer surface of threaded tube, mounting bracket is installed on the lower surface of moving frame, the utility model is used to solve the gap between suture and coating brush in prior art, to cause the problem that part position on suture surface is difficult to adhere coating.

This invention relates to the field of stapler technology, specifically a tracking-type electric laparoscopic stapler with absorbable suture needle. It includes a housing, a closing handle rotatably mounted inside the housing, a linkage bracket fixedly connected to the closing handle, an operating mechanism disposed at one end of the linkage bracket, and a limiting mechanism and an electric drive mechanism disposed inside the housing. A sliding bracket is slidably mounted inside the housing, and a transmission rack is fixedly mounted inside the sliding bracket. The housing also includes a lifting frame, an adjustment mechanism, and a first transmission mechanism. A locking mechanism and a connecting mechanism are respectively disposed at the top and bottom of the sliding bracket. This invention solves the problem that a failure in the motor drive mechanism can cause the stapler to jam, interrupting the surgical process and delaying patient treatment, further improving the reliability and clinical applicability of electric staplers in the biomedical engineering industry.

The present application relates to a kind of intelligent color-changing absorbable suture and its preparation method, belong to medical instrument field.The suture includes inner layer support layer, response layer, drug release system and outer layer encapsulation layer.The inner layer support layer is made of absorbable polymer;Response layer includes pH response unit and enzyme response unit, can produce identifiable color change under tissue infection microenvironment;Drug release system is loaded with antibacterial drug by mesoporous nano-carrier and is modified with polyelectrolyte gate layer, triggers drug burst release under microenvironment change;Outer layer encapsulation layer is at least partially degradable, to expose response layer after predetermined time.The suture realizes phased degradation by three-layer structure: outer layer encapsulation layer is preferentially degraded to expose response layer, response layer degradation provides infection monitoring window period, and inner layer support layer is lastly degraded to maintain mechanical support, realizes the synergistic function of infection monitoring, drug release and tissue repair.

The invention relates to the technical field of medical materials, and particularly discloses a non-absorbable suture with excellent biocompatibility and a preparation method of the non-absorbable suture. The non-absorbent suture provided by the invention comprises a core layer, a transition layer and a surface functional layer, the core layer and the transition layer are interwoven and fixed through electrostatic spinning, and the surface functional layer is fixed on the surface of the transition layer through vapor deposition polymerization; the diameter of the core layer is 20-50 microns, and the porosity of the core layer is less than 5%; the transition layer is made of polyether-ether-ketone of which the mesh aperture is 10-15 microns and the thickness is 5-10 microns; the surface functional layer is a zwitterionic polymer covalently grafted with phosphorylcholine, and the thickness of the zwitterionic polymer is 0.5-1.2 [mu] m; the invention further provides a preparation method of the non-absorbent suture. The non-absorbable suture has the advantages of being good in biocompatibility, good in long-term mechanical stability and the like, and is suitable for medical suture scenes needing lasting support.

The present application relates to the technical field of traditional Chinese medicine acupuncture and physiotherapy, and particularly relates to a traditional Chinese medicine acupoint catgut implantation, which comprises a special catgut implantation device and a standardized operation method. The device is composed of a disposable puncture needle and a special adapter for poly-p-dioxanone absorbable suture thread. The puncture needle adopts a polycarbonate needle holder, a stainless steel needle tube and a polypropylene sheath, is sterilized by ethylene oxide, and is divided into two kinds of kits, i.e. a needle integration kit and a thread segment combination kit. The present application realizes 13-month long-acting acupoint stimulation through absorbable thread, combines traditional Chinese medicine meridian regulation and modern biomedical mechanisms, effectively solves the problems of short time efficiency, non-standard operation and insufficient safety in traditional acupuncture and moxibustion, and has the characteristics of simple operation, sterile safety, stable curative effect and no need for frequent reexamination, and is suitable for chronic and intractable disease conditioning and beneficial to basic medical popularization.

The invention relates to an intelligent color-changing absorbable suture line and a preparation method thereof, and belongs to the field of medical instruments. The suture line comprises an inner supporting layer, a response layer, a drug release system and an outer packaging layer. Wherein the inner supporting layer is composed of an absorbable polymer; the response layer comprises a pH response unit and an enzyme response unit, and can generate recognizable color change in a tissue infection microenvironment; the drug release system is formed by loading an antibacterial drug on a mesoporous nano-carrier and modifying the mesoporous nano-carrier with a polyelectrolyte gating layer, and drug burst release is triggered under the change of a microenvironment; the outer encapsulation layer is at least partially degradable to expose the response layer after a predetermined time. According to the suture line, staged degradation is achieved through a three-layer structure, the outer packaging layer preferentially degrades and exposes the response layer, the response layer degrades to provide an infection monitoring window period, the inner supporting layer finally degrades to maintain mechanical support, and the synergistic function of infection monitoring, drug release and tissue repair is achieved.

The application relates to the technical field of medical devices, in particular to a polymer modified absorbable suture, which comprises an outer antibacterial layer, a connecting line and a tie, the inner part of the outer antibacterial layer is internally provided with an inner antibacterial layer, the inner part of the inner antibacterial layer is internally provided with a toughness layer, and the toughness layer is fixedly connected with a reinforcing layer in the inner part, when suturing, the device is cut to select a proper length, the connecting line between the two outer antibacterial layers is cut, the connecting line is then passed through a needle hole to connect the device to the needle hole, the needle is penetrated, the flat-elliptical connecting line is more convenient for a user to penetrate the needle, the needle penetration time is effectively reduced, and the device is more convenient to use.

The present application belongs to the technical field of medical suture disassembly reel, especially to an absorbable suture anti-pollution disassembly reel. In view of the problems existing in the prior art, the following scheme is proposed, including a rotating column, a extrusion groove is arranged on the circumferential side of the rotating column, a moving groove is arranged on the top and bottom of the extrusion groove, a circular plate is slidably connected to the top inner wall of the circumferential side of the moving groove, a moving column is fixedly connected to the bottom of the circular plate, and the other end of the moving column extends into the interior of the extrusion groove. The rotating column is arranged, the user uses tweezers and other tools to insert one end of the absorbable suture between the two lifting plates, rotates the rotating shaft to drive the major axis of the elliptical block to stagger the lifting plates, and at the same time, the second spring drives the two sets of extrusion plates to press the one end of the absorbable suture, which is beneficial to the convenient fixation of the absorbable suture, improves the convenience of the device in use, and the rotating column drives the absorbable suture to be evenly wound on the rotating column.

The application discloses a silk protein-containing absorbable suture and a preparation method thereof, and relates to the technical field of absorbable sutures.The silk protein-containing absorbable suture comprises the following raw materials in parts by weight: 35-50 parts of silk protein, 10-20 parts of polylactic acid, 15-25 parts of polyglycolide, 1-3 parts of an antibacterial agent, 2-5 parts of a modified toughening agent, 1-4 parts of a nano-mineral filler, 0.5-2 parts of a crosslinking agent and 2-5 parts of a plasticizer.The application generates an intermediate 1 by reacting protocatechuic acid with ethanolamine; the intermediate 1 is reacted with 5,10,15,20-tetra(4-carboxyphenyl)porphyrin to generate the antibacterial agent.The silk protein-containing absorbable suture prepared by the application has good mechanical properties, self-repairing properties and antibacterial properties.

The invention relates to the technical field of medical instruments, in particular to a gradient degradation composite absorbable suture line and a preparation process. The invention discloses a gradient degradation composite absorbable suture line which sequentially comprises a supporting layer, a middle layer and an outer layer from inside to outside in the radial direction, and the outer layer is prepared from, by weight, 50%-70% of polyglycolic acid, 20%-35% of polyethylene glycol-polylactic acid segmented copolymer and 5%-10% of basic salt buffering particles. According to the composite absorbable suture line and the preparation process, through material compounding and structural design, staged regulation and control of the degradation rate and the mechanical strength are achieved, and it is ensured that the strength of the suture line is synchronous with the tissue healing process.

The application relates to the technical field of medical devices, and discloses an absorbable door opening maintainer for cervical vertebra canal plasty, wherein the maintainer body is integrally formed by using high-strength absorbable material, a hollow bone ingrowth matrix is arranged in the maintainer body in the axial direction, the maintainer body comprises a spiral coupler structure and a zero-cut trace cable structure, and the spiral coupler structure and the zero-cut trace cable structure are both hollow structures. In the application, the whole maintainer is made of high-strength absorbable material, is matched with absorbable sutures of the same type, the degradation periods of the two are mutually adapted, the degradation process is synchronized with the bone growth period, secondary surgery for removal is not needed, secondary damage to bone and soft tissues is avoided, the multi-dimensional bone ingrowth channel is beneficial to the migration, proliferation and angiogenesis of bone cells, biological fusion between the maintainer and the host bone is promoted, and the bone repair process is accelerated.

The invention belongs to the technical field of medical materials, and particularly relates to an antibacterial super-smooth absorbable suture line and a preparation method thereof. Compared with the prior art, the antibacterial super-smooth absorbable suture line prepared by the invention can avoid winding and slipping of the suture line during knotting, reduce tissue damage, reduce release of a pain medium, promote wound healing and shorten the recovery time of a patient; meanwhile, the super-smooth surface can reduce bacterial adhesion through physical repulsion, and the super-smooth surface and antibacterial groups form double protection of physical blocking and chemical killing; the antibacterial agent is fixed on the surface of the suture line in a covalent bond combination mode through a grafting technology, no free antibacterial agent exists, local irritation is low, the specific surface area of the suture line can be effectively increased, and the antibacterial efficiency is improved.

The invention provides a circumcision anastomosis device which can finish circumcision anastomosis with high precision and simple operation and can replace a suturing nail by adopting an absorbable line, and the circumcision anastomosis device comprises a positioning piece, a fixing piece and a fixing piece, the shell is provided with a matching end matched with the positioning piece; the girdling part is used for girdling the prepuce part to form a part to be sutured; the suturing piece is rotatably arranged in the shell and is provided with a suturing knob; each first suture needle is provided with an arc-shaped needle part facing the matching end, a first threading groove is formed in the tip part of each arc-shaped needle part, and a thread clamping groove is formed in the middle of each arc-shaped needle part; the second suture needle is arranged at the end, close to the matching end, of the suture piece and provided with a second threading groove, a first suture line penetrates through the thread clamping grooves and the first threading groove jointly, and a second suture line penetrates through the second threading groove. The device further comprises a driving mechanism for driving the first suture needle to slide towards the matching end and enabling the arc-shaped needle parts to jointly penetrate into the to-be-sutured part.

The invention relates to the technical field of breast surgery, and discloses a breast areola beautifying incision surgery method for breast mass resection by reserving a nipple areola complex, which comprises the steps of preoperative evaluation, iconography positioning, incision design, preoperative preparation, mass exposure resection, incision suture and the like: accurate positioning is carried out through ultrasound or a molybdenum target; based on a positioning result, designing an annular mammary areola incision along a mammary areola edge skin pigment boundary line; the tissue is bluntly separated in the operation to protect the mammary gland function, and the tumor is completely cut off along the safe edge; and finally, performing layered sewing by using an absorbable suture to realize intradermal beauty sewing. According to the invention, scars are covered by chromatic aberration through surrounding the mammary areola incision, postoperative traces are reduced in combination with multi-layer fine suture, meanwhile, complete resection of mastitis is ensured, the treatment effect and the appearance attractiveness of breasts are considered, and the mammary gland resection device is suitable for mammary gland mastitis, mastitis focus and total mammary gland resection patients needing to retain nipple and mammary areola complexes. And particularly, the requirements of young women on postoperative appearance are met.

The invention provides a nanoparticle dynamic antibacterial absorbable suture line and a preparation method thereof, and belongs to the technical field of biomedical materials. According to the suture line, the problems that a traditional suture line is insufficient in antibacterial performance, low in mechanical strength and uncontrollable in drug sustained release are solved by constructing a three-level heterostructure; polyvinyl alcohol, polycaprolactone, mesoporous silica and Ag-Cu bimetallic nanoparticles are adopted as raw materials; the dynamic antibacterial suture line with the three-level heterostructure is successfully prepared through the steps of spinning solution preparation, fiber forming and drafting, composite coating colloid preparation, a dipping-spin coating combined process, irradiation crosslinking and the like. According to the method, by constructing a pH / lysozyme double-trigger intelligent drug release system, accurate antibacterial performance related to the infection degree is achieved, and antibiotic dependence is avoided. The tensile strength of the product reaches 120-180 MPa, the antibacterial rate of the product to escherichia coli and staphylococcus aureus reaches 99.99%, and the product is widely applicable to various clinical scenes such as clean surgical incision closure, polluted wound repair, chronic wound management and high-risk infection operations.

A marking device for rapid intraoperative identification of target lymph nodes includes a medical titanium clip. One end of the clip is connected to a marking line, the other end of which is a free end. The marking line is a non-absorbable medical suture, 15-20 cm in length. This invention does not require changes to the way the titanium clip is used. Under real-time ultrasound guidance, the medical titanium clip is placed on the target lymph node via puncture, and the severed outer end of the marking line is buried superficially under the skin. When the target lymph node needs to be removed, under real-time ultrasound guidance, the position of the medical titanium clip is initially determined. Then, an incision is made at the puncture site from the insertion point, and the non-absorbable medical suture is located. The patient is then guided along the non-absorbable medical suture until the medical titanium clip is reached. This allows for rapid identification of the target lymph node in the surgical field, providing a highly intuitive and convenient method, thus avoiding the omission of target lymph nodes. This benefits patient treatment decisions and prognosis, reduces surgical time, and minimizes the surgical area.

The utility model relates to the field of animal experiments, in particular to absorbable suture implantation observation equipment for animal experiments. Comprising an X-ray machine, a detector is arranged at the upper end of the X-ray machine, a workbench is installed on the surface of the X-ray machine, an adjusting structure is arranged on the upper surface of the workbench and comprises an adjusting frame, the adjusting frame is fixedly connected with the workbench, a two-way screw rod is rotationally connected to the inner wall of the adjusting frame, and the two-way screw rod is fixedly connected with the workbench. Handles are fixedly connected to the two ends of the two-way screw rod, two moving blocks are in threaded connection with the arc surface of the two-way screw rod, and the two moving blocks are in sliding connection with the inner wall of the adjusting frame. The absorbable suture line implantation observation equipment for the animal experiment has the advantages that the binding belts are used for binding the four limbs of an animal, the supporting plate is moved, the four limbs of the animal are pulled and unfolded through the ropes, the operation of binding the animal is fast, the position flexibility of parts such as the positioning frame and the supporting plate is high, and the absorbable suture line implantation observation equipment is suitable for binding animals of different body types and sizes.

The invention discloses a time period limiting type reverse shoulder joint prosthesis, and relates to the field of joint prostheses, the time period limiting type reverse shoulder joint prosthesis comprises a humerus base, a spacer is installed at the top end of the humerus base, a polyethylene lining is installed at the top of the spacer, and a shoulder glenoid ball is attached to the end face of one side of the polyethylene lining; the end face of one side of the shoulder glenoid ball is in threaded connection with a shoulder glenoid base, a shoulder glenoid opening is formed in the inner side of the shoulder glenoid ball, an absorbable suture line penetrates through the inner side of the shoulder glenoid opening, a humerus base opening is formed in the inner side of the humerus base in a penetrating mode, and the absorbable suture line penetrates through the shoulder glenoid opening and the humerus base opening and is fixed in the shoulder glenoid opening and the humerus base opening. In the early stage of prosthesis implantation, the shoulder joint is limited, so that the shoulder joint becomes a restrictive prosthesis temporarily, it is guaranteed that the joint cannot be dislocated, and the absorbable suture can be absorbed within about 56-78 days in the post-operation process of a patient.

The present disclosure relates to an absorbable suture. The absorbable suture includes an absorbent polymer and polydeoxyribonucleotide (PDRN) contained in the absorbent polymer.