175 results about "Nutraceutical" patented technology

The present invention relates to a novel association or combination of active ingredients useful in the prevention and repair of neuronal damage, both centrally and peripherally. In greater detail, the present invention relates to an association or combination of i) an extract of Gastrodia elata and ii) at least one ingredient selected from the group comprising or, alternatively, consisting of citicoline, L-acetylcarnitine and, preferably, at least one vitamin of group D, and / or mixtures thereof, and / or at least one vitamin of group B, and / or mixtures thereof. Furthermore, the invention also relates to the pharmaceutical compositions and / or compositions for medical devices (Regulation (EU) 2017 / 745) and / or nutraceutical and / or food compositions comprising that association and to their use in therapy, in particular in the protection of the functionality of the nervous system and in the prevention and / or treatment of central and peripheral neuropathies.

The invention relates to the technical field of nutrition health care product customization, and discloses a personalized adult nutrition health care product customization system and method. The method comprises the following steps: collecting biological characteristics, dietary habits, health targets and gene detection data of a user, and constructing a nutritional requirement database through labeling and preprocessing; a multi-dimensional nutrition demand tensor is generated through principal component analysis, clustering analysis and the like, the matching degree of a target user and a representative sample is calculated, a weighted matching degree vector is obtained through neural network optimization, and then a personalized nutrition formula substrate is generated and optimized through a genetic algorithm. Kalman filtering is used for adjusting a formula according to real-time health data of a user, monitoring deviation to trigger reconstruction, associating a historical scheme to update a nutrition rule base, and finally outputting a nutrition formula coded as a production instruction, so that accurate personalized customization is realized, and nutrition is safe, reasonable and traceable.

The invention provides methods for the preparation of particles including one or more agents, e.g., therapeutic or diagnostic agents. The particles can be formed by creating droplets of a first liquid, e.g., including an agent, and removing the first liquid, e.g., through its dispersal in a second liquid and / or evaporation, to solidify the droplets. Advantageously, the process of forming the particles does not significantly alter the structure or activity of the agents and may enhance the stability of the agents. For example, the particles may be stored for long periods of time without significant loss of activity, and in some embodiments, without the need for refrigeration. These particles may be used to generate stabilized pharmaceutical compositions for storage or other logistical purposes, pharmaceutical suspensions, pharmaceutical powder formulations (e.g., inhalable powders, injectable powders), creams or other topical pastes, nutraceuticals, or cosmetics.

The invention discloses a preparation method of a lactoferrin-polyphenol nano compound with an intestinal immune function. The method comprises the following steps: firstly, moderately hydrolyzing lactoferrin under the action of compound protease, and optimizing a protein molecular structure; then, compounding with water-soluble polyphenol (such as chlorogenic acid or epicatechin) by utilizing a metal ion chelating technology, and inducing lactoferrin to be bridged and aggregated by Ca to form a compound; and then, carrying out ultrasonic homogenization treatment, and further controlling the particle size to enable the particle size to be distributed in a range of 100-300 nm. The obtained compound is subjected to nanofiltration concentration and electrostatic spray drying to obtain a shell-core nano compound with a stable structure, and nitrogen-filled packaging is adopted to prevent oxidation. The lactoferrin-polyphenol nano-composite prepared by the invention not only has good stability and intestinal immunity enhancement effect, but also has remarkable antibacterial activity, and can be widely applied to functional foods and nutritional health-care products.

The invention discloses a grape seed protein peptide with DPP-IV inhibitory activity and a preparation method thereof, and belongs to the field of comprehensive utilization of wine fermentation byproducts. The grape seed protein peptide disclosed by the invention is prepared from a zymolyte obtained by carrying out alkaline protease enzymolysis on grape seed protein prepared from grape seeds by an ultrasonic-assisted alkaline method. The grape seed protein peptide disclosed by the invention has a good DPP-IV inhibition effect, is a DPP-IV inhibitor from a natural plant source, and can be applied to functional foods and nutritional health-care products.

To provide a method for determining when a natural therapeutic or beneficial product will exert its therapeutic or beneficial effect via a physiological mechanism of action.SOLUTION: The present invention relates to a new method that allows the evolution of medical technologies from the use of chemically or biologically defined artificial substances to self-assembling natural products obtained from natural raw materials by industrial processes that preserve their endogenous properties, thereby preserving their ability to interact with the networks of the living world (including humans), which natural products cannot be defined with classical qualitative and quantitative composition schemes. Thus, the present invention provides a new method for determining when a therapeutic or beneficial product exerts its therapeutic or beneficial effect via a physiological mechanism of action. This method provides the tools necessary for the skilled person to assess the mechanism of action of a therapeutic or beneficial product, which has become a relevant feature to assess with new developments in regulatory regimes for medical devices and nutraceuticals, for which there is no method available in the art.SELECTED DRAWING: None

The present invention relates to a mycelium component derived from submerged fermentation of at least one fungal strain in three different media: a defined component medium producing component A, a synthetic medium producing component B, or a composite natural medium producing component C comprising a sidestream extract derived from an agricultural food sidestream. This unique mycelium composition is characterized by chemical, biological, physical, morphological, nutritional and organoleptic properties. The three different fibrous mycelia of the edible fungi obtained from at least one fungus strain are further used to produce characteristic food products, including meat analogs, fish analogs, dairy product analogs, beverages, or other food products. The three new mycelium components are useful in the manufacture of foods, foods, beverages, pharmaceuticals, cosmetics, nutraceuticals, biomaterials, and feed and industrial applications.

The present invention relates to a solid nutraceutical composition for the prevention and treatment of cognitive disorders, consisting of an emulsion and a mixture of seed and oil, all of which are naturally derived. The emulsion contains plukenetia volubilis oil; an extract of plant origin, such as turmeric, pepper or cocoa; an emulsifier selected from lecithin, saponaria or maguey extract, or egg white; the sweetening agent is selected from fructo-oligosaccharide, stevia rebaudiana or maguey extract, Italian bee honey and cane sugar; and air is contained. Seeds and oil include pumpkin seeds and plukenetia volubilis oil. Other ingredients selected from cocoa powder, coconut oil, fruit or seed mass, natural juice and protein are also added. Thus, the nutraceutical comprises 3 to 5 sources of fatty acids, phytosterols and triacylglycerol, 2 to 8 sources of antioxidants, up to 3 sources of hypoglycemic agents, and up to 4 sources of anti-cholesterol and anti-inflammatory compounds. In addition, the nutritional health-care product also contains proteins, vitamins, macroelements, microelements and substances for promoting chewing and swallowing of subjects and patients suffering from cognitive impairment. The nutritional health-care product is suitable for preventing and treating Alzheimer's disease; mental, behavioral and developmental disorders, including depression; neurological, digestive, immune, endocrine and circulatory disorders; cardiovascular, cerebrovascular, infectious, parasitic, neoplastic and blood diseases; fatigue, fatigue and malnutrition.

The subject of the invention is an application of white birch liquid for improving memory. The invention discloses an application of a betula platyphylla sap extract in preparation of a medicine or a health food, wherein the medicine or the health food is beneficial to improving memory disorder. The invention further discloses a preparation method of the betula platyphylla sap extract, and an application of the betula platyphylla sap extract in preparation of the medicine or the health food. The white birch extract related product disclosed by the invention has the characteristics of high efficiency, safety and convenience, and can be used for effectively treating, preventing or slowing down the dysmnesia in manners of medicines, diet intervention or nutritional health-care products and the like. The invention also provides methods of treating, preventing or slowing memory disorders using the betula platyphylla extract.

Disclosed are broccoli plant extracts and nutraceuticals including the same that have increased levels of anti-inflammatory chemicals. Also provided are exosomal preparations containing the broccoli plant extracts and nutraceuticals as well as methods of using the broccoli plant extracts and nutraceuticals for treating inflammation and treating or reducing the risk of cancer recurrence in a subject.

Verbascum nigrum extracts are disclosed, as well as processes for preparing the same and uses as active ingredients in nutraceuticals. In particular, it is disclosed an enzymatic process wherein a specific enzyme cocktail is used for selectively releasing and extracting compounds from a Verbascum nigrum biomass. It is also disclosed a hydroalcoholic process for releasing and extracting different compounds from a Verbascum nigrum biomass. Said Verbascum nigrum biomass is advantageously obtained from vertical farming, which allows to maximize the stability and properties' reproducibility of the botanical with respect to the corresponding wild-growing plants. The resulting enzymatic and hydroalcoholic extracts can be advantageously used singularly or in combination thereof, thus taking benefit of the overall active compound mixture. Specifically, the extracts can be suitable used in nutraceutical compositions and food supplements.

The present invention is based on the highly soluble and bioavailable cannabinoid compositions which can be made at a commercial scale with a simple manufacturing process. Thus, the present invention relates to oral compositions comprising a cannabinoid compound, for use in the nutraceutical, pharmaceutical, food or beverage industries and its production methods.

The application discloses a personalized pet nutrition and health care product recommendation method and system, and relates to the field of artificial intelligence. The specific steps comprise the following steps: collecting pet related information and labels from multiple source systems; performing normalization and nonlinear interaction feature construction on numerical features, and performing adaptive embedding and category cross on category type features to obtain enhanced original vectors; screening features by using label association information, and performing clustering fusion to obtain a fusion feature matrix; adopting an improved feature cross network, introducing low-rank decomposition and pet health knowledge prior to construct a classification model; constructing a loss function introducing a rule constraint regular term, training the model and updating parameters; and recommending nutrition and health care products to pets by using the trained model. The application can accurately capture the complex relationship between features, and significantly improve the accuracy of model prediction.

The present invention provides a novel room-temperature extraction system and method for cannabis and hemp, utilizing custom membrane filtration to efficiently isolate cannabinoids, terpenes, and other bioactive compounds while reducing energy consumption. This multi-stage system begins with a custom milling machine that preprocesses biomass by separating non-target components, such as cellulose-rich stalks, to improve extraction efficiency. The core extraction process employs a series of custom membranes designed to selectively filter cannabinoids and terpenes, minimizing impurities without the need for traditional sub-zero cooling. Each membrane stage incorporates solvent recovery to recycle ethanol, reducing waste and operational costs. In the final stage, a custom concentrator removes residual ethanol, decarboxylates THCa to THC, and crystallizes sugars to prevent downstream clogging. This room-temperature extraction system significantly enhances yield, purity, and sustainability, making it a scalable and cost-effective solution for cannabis and hemp processing industries, as well as applicable for pharmaceutical and nutraceutical uses.

The invention belongs to the field of food science and engineering, and discloses a preparation method of an active medicinal and edible composite nutrient AMCN with an anti-aging effect, and the preparation method comprises the following steps: putting a ganoderma lucidum monoclonal strain into a liquid culture medium for controllable culture to obtain supernate with beta-glucosidase activity of over 100mU / mL; and adding rhizoma polygonati powder, lucid ganoderma powder and mulberry leaf powder, carrying out enzymatic biotransformation, carrying out lactobacillus plantarum fermentation, adding a freeze-drying protective additive, carrying out freeze-drying, grinding to obtain the active medicinal and edible composite nutrient AMCN, and storing the finished product in a dry and dark place. The active medicinal and edible composite nutrient can be used for preparing anti-aging functional foods or nutritional health-care products. A D-galactose induced zebrafish aging model verifies that the active medicinal and edible composite nutrient prepared by the application plays an anti-aging role by relieving oxidative stress, inhibiting cell aging and maintaining telomere stability, can reduce beta-galactosidase activity and intracellular ROS (reactive oxygen species) level, improves telomerase protein concentration, and has a good anti-aging effect. And the telomere length can be effectively recovered by medium and high concentrations.

The present invention refers to nutraceutical compositions, to plant extracts and complex coacervates comprising them. The present invention further refers to uses thereof.

The present invention pertains to a pharmaceutical, or nutraceutical, “self-emulsifying solid dispersion” composition for oral administration which contains (a) a drug or a nutraceutical that is water-insoluble or poorly water-soluble; (b) at least one surfactant; (c) one carrier selected from the group consisting of silicic acid, a silicate, or any combination thereof; and (d) at least one carbohydrate filler.

The invention relates to a functional nutritional composition, in particular to an anti-fatigue diglyceride composition, which is characterized by comprising (1) diglyceride, (2) isomaltooligosacharide, (3) sodium caseinate, (4) soybean phospholipid, (5) sodium citrate, (6) potassium citrate, (7) calcium ascorbate, (8) silicon dioxide, (9) mogroside, (10) vitamin B1 and (11) vitamin B2. The composition disclosed by the invention can be used as an anti-fatigue beverage, a nutritional health-care product, a food for special diets, a food for special medical purposes and the like.

Compositions comprising polysaccharides and oligosaccharides are provided. Methods for the formation of the compositions, including the enzymatic production of the oligosaccharides, and the uses of the compositions in foodstuffs, cosmetics, and nutraceuticals are also provided.

A system (100) and method (900) for dispensing a personalized nutraceutical (81) to a consumer (62). The system (100) can create the personalized nutraceutical (81) that is selectively influenced by one or more health attributes (640) relating to the intended consumer (62) of the personalized nutraceutical (81). The application(s) (373) of the system (300) can create a variety of outputs (690) including a personalized recipe (693) for the personalized nutraceutical (81) from a variety of inputs (610) that can include the health attributes (640) of the consumer (62). A production assembly (500) can manufacture the personalized nutraceutical (81) using the personalized recipe (693).

The invention provides a process for preparing a plasticised superporous hydrogel material comprising subjecting initial hydrogel material to treatment with an acidic solution, an optional treatment with a monovalent metal salt solution, freeze drying and plasticisation. Optionally, the process of the invention produces moulded plasticised superporous hydrogel material bodies that have one or more through-holes formed therein. The plasticised superporous hydrogel material of the present invention may be formulated as a suitable oral dosage form for use an appetite suppressant and for use to deliver a pharmaceutical and / or nutraceutical into a human or animal body.

In an iron (II) citrate monohydrate, identified by the formula FeC6H6O7-H2O ( Ferrous citrate monohydrate or iron citrate (II) monohydrate), obtained according to a particular production method, citric acid and elemental iron are bound in a molecular complex where the iron is agglomerated in the citrate which moves to a cyclic form and the iron is bound to the O groups of the carboxylic groups 1 and 3 through ionic bonds, forming two enantiomers, D and L (R and S), both perfectly water-soluble and highly assimilable by the human body. Formula (L) & Formula (D). With a different absorption mechanism from traditional iron molecules, said iron citrate monohydrate is usable in pharmaceutical and / or nutraceutical and / or food compositions, in particular in the treatment and prevention of iron deficiency anemias and in general of all diseases and disorders associated with iron deficiency. The effectiveness is proven by several examples.

The present disclosure relates to methods, devices and systems for exposing microorganisms or compositions comprising functional proteins to an oscillating electric field substantially free of a magnetic component in order to improve stress responses, survival and metabolite or protein production. In embodiments, a controller drives one or more insulated emitters with a true AC signal or pulsed DC signal, in stepped, swept or shuffled patterns of an electric field oscillating at one or more frequencies in the range 210 Hz to 99 kHz. Exposure to the field provides surmounting energy that enhances protein breathing, catalysis, and fundamental functions of multiprotein complexes including transcription factors and ribosomes, thereby improving stress resistance of microorganisms, their viability during fermentation, drying, storage, transport, and / or increasing production of functional or therapeutic proteins, metabolites or microbial lysates. The technology is applicable to manufacture of probiotics, therapeutics, metabolites, food, alcohol, feed and bioenergy, cosmetics, nutraceuticals and biopharmaceuticals..

Homogeneous human amniotic fluid stem cell clones are provided. The clones serve as direct bioassays to test the effect of drugs, nutraceuticals, vitamins and toxic agents on fetus growth, differentiation and development, and may be administered in form of pharmaceutical compositions for reconstructive engineering and for the treatment of cardiac, neurological and osteoarthritic diseases.

The invention provides an iron-free oxygen removal composition. The iron-free deoxidizing composition comprises ascorbyl palmitate, a natural antioxidant, activated carbon, adsorption silica gel, a 4A molecular sieve and water. The natural antioxidant comprises lycopene, ginger, orange and lemon powder. In the composition, the ratio of ascorbyl palmitate to lycopene powder to other components (activated carbon, adsorption silica gel with the water activity of 0.47-0.60 and a 4A molecular sieve) is maintained to be 3.2: 1.1: 1.4. The iron-free deoxidant composition has enhanced oxygen uptake capability, and can remove oxygen, moisture and peculiar smell in the package at the same time. The iron-free deoxidant composition is environment-friendly, and can prolong the shelf life of medicines, foods and nutritional health-care products.

The invention relates to the technical field of biology, in particular to a preparation method of plant exosome-like nano vesicles. The method comprises the steps of juicing, centrifugation, filtration, ultrafiltration and the like. According to the method, ultrafiltration tubes of different specifications are adopted for ultrafiltration and centrifugation, the plant exosome-like nano-vesicles can be rapidly and mildly separated, and the obtained vesicle membrane is complete in structure, obvious in double-layer membrane and good in active substance retention effect. The preparation method provided by the invention has the advantages of simple and easily available process and equipment, no need of additional addition of reagents, easiness in control, low cost and suitability for obtaining high-yield vesicles in a short time, can be used as a drug delivery carrier, and shows good application potential in the fields of skin care products, medical beauty products, functional foods and nutritional health-care products.

The present disclosure describes economical processes to improve the bioavailability of nutraceuticals by formulations that induce micronization and sustained release. The inventive process can be used to increase the solubility and bioavailability of lipophilic and moderately water-soluble nutraceuticals by combining excipients that increase the solubility and induce sustained release of the active compounds. The inventive process also can be used to increase the residence time of highly water-soluble nutraceuticals that are metabolized and eliminated quickly from the body, consequently increasing the therapeutic potential. The disclosed formulations advantageously are freely flowing powders that can be used to formulate with other ingredients into tablets, capsules, or the like; or used as bulk powders.

The present invention relates to compositions in the form of cationic microemulsion preconcentrates that contain at least one lipophilic and water-insoluble active agent, at least one polyglyceryl-containing emulsifier, at least one cationic emulsifier, carrier oils, solubilizers, antioxidants, and preservatives. When contacted with either an aqueous medium, gastric or intestinal fluid, the cationic microemulsion preconcentrates self-assemble into cationic microemulsions that are stable in gastric and intestinal fluids. The invention is also related to methods of making and methods of using the cationic microemulsion preconcentrates.

The present invention relates generally to methods and compositions useful for treating skin on a subject. In some embodiments, methods and compositions disclosed herein comprise topical or oral administration of nutraceutical and / or topical composition, wherein the composition comprises at least two of puerarin, collagen, and hyaluronic acid.

The present invention relates to a glycan composition useful as nutritional supplement, such as for infant formula supplement and as nutraceutical products and a method of preparation thereof.