60 results about "Generally recognized as safe" patented technology

The invention relates to medicaments comprising a microbicidal composition consisting of at least two GRAS (Generally Recognized As Safe) aromatic agents or derivatives thereof, and to the use of these compositions for producing decontamination and / or regenerative agents for treating humans and animals.

The Federal EPA has consistently limited the use of known toxicants (insecticides) to preclude their admixture into paints and coatings by contractors or homeowners for the purpose of repelling or killing insects on the dried or cured coating. The current invention utilizes materials taken from the EPA's GRAS (Generally Recognized as Safe) List for this purpose. Furthermore, the current invention utilizes the insect repellant nature of these materials to repel insects from the area during coating application, thereby eliminating the need for topical insect repellants such as DEET.

Rinse aid compositions and methods for using and methods for making the compositions for warewashing processes. In one aspect, the rinse aid composition includes ingredients listed on the FDA GRAS (“generally recognized as safe”) list, including 21 C.F.R. 172 and / or 21 C.F.R. 178; preferably, all the ingredients are listed on the GRAS list. The rinse aid composition includes at least two ethylene oxide-propylene oxide (EO / PO) copolymers, with at least one of those EO / PO copolymers being PO-terminated. The rinse aid composition can include two PO-terminated EO / PO copolymers.

Environmentally friendly solvents used to dissolve or remove residues and / or substances from substrates wherein the residue and / or substance is contacted with a Generally Recognized As Safe solvent to dissolve the residue and / or substance in the solvent followed by the extraction of the residue and / or substance from the solvent such as by contact with carbon dioxide.

The invention discloses a preparation method for meat flavor based on man-machine analysis, and the title for the invention is GC-O-MS assisted preparation method for strengthened thermal response savory flavoring. The method is characterized in that: a GC-O-MS device is used to determine the substance that is detected simultaneously in retention index, mass spectrum and organoleptic evaluation, which enables subjectivity and fuzziness of conventional organoleptic evaluation to be avoided; the GC-O-MS device can rapidly screen flavor activity compounds in a simulated foodstuff and determine the importance of the flavor activity compounds in the flavor of the foodstuff as a whole and can accurately identify and provide guidance to the variety and content of critical compounds capable of restoring meat flavor, and compounds with a flavor activity value more than 1 is prepared into strengthening essential oil; the essential oil mixed with a thermal response meat flavor base. In the method, the strengthening essential oil derives from food, the thermal response meat flavor base is generally recognized as safe, and the strengthened thermal response meat flavoring prepared in the invention is more mellow and natural than a pure blended meat flavor essence.

Provided are biocide compositions and bleach compositions comprising organic acyl polyoxychlorine and related methods. The reduction of the acyl polyoxychlorine group releases a reactive intermediate that undergoes a series of cascading reduction steps, resulting in termination products Generally Recognized As Safe.

Environmentally friendly solvents used to dissolve or remove residues and / or substances from substrates wherein the residue and / or substance is contacted with a Generally Recognized As Safe solvent to dissolve the residue and / or substance in the solvent followed by the extraction of the residue and / or substance from the solvent such as by contact with carbon dioxide.

Gels are formed based on generally recognized as safe (GRAS) low molecular weight amphiphilic molecules in a self-assembly process with limited or no heating. A selective range of ratios between an organic solvent and water, or an aqueous solution, in the medium, allows for the GRAS low molecular weight amphiphiles to form a homogeneous self-supporting gel encapsulating agents to be delivered under very mild conditions. Proteins including enzymes, antibodies, and serum albumin are loaded in the self-assembled gels to provide sustained and / or responsive delivery. The encapsulated proteins retain at least 70%, 80%, or 90% of their activity over days in various storage conditions.

The Federal EPA has consistently limited the use of known toxicants (insecticides) to preclude their admixture into paints and coatings by contractors or homeowners for the purpose of repelling or killing insects on the dried or cured coating. The current invention is a method to repel, rather than kill, insects, arachnids, and other arthropods, utilizing materials taken from the EPA's GRAS (Generally Recognized as Safe) List, obviating onerous Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) regulations and greatly extending the useful life of the insect-repellant materials by binding them into the dried film solids—greatly slowing their evaporation and degradation and creating a timed release of insect repellant material. Furthermore, the current invention utilizes the insect repellant nature of these materials to repel insects from the surrounding area during coating application, thereby eliminating the need for applying insect repellants, such as DEET, to the skin.

The present invention provides an effective method of inhibiting corrosion on metallic surfaces in contact with a fluid contained in an industrial fluid system, which includes adding to such fluid an effective corrosion controlling amount of a particular generally recognized as safe (GRAS) compound.

The Federal EPA has consistently limited the use of known toxicants (insecticides) to preclude their admixture into paints and coatings by contractors or homeowners for the purpose of repelling or killing insects on the dried or cured coating. The current invention is a method to repel, rather than kill, insects, arachnids, and other arthropods, utilizing materials taken from the EPA's GRAS (Generally Recognized as Safe) List, obviating onerous Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) regulations and greatly extending the useful life of the insect-repellant materials by binding them into the dried film solids—greatly slowing their evaporation and degradation and creating a timed release of insect repellant material. Furthermore, the current invention utilizes the insect repellant nature of these materials to repel insects from the surrounding area during coating application, thereby eliminating the need for applying insect repellants, such as DEET, to the skin.

Antimicrobial compositions comprising one or more compound components generally recognized as safe for human consumption, and related methods of use, such compositions and methods as can be employed in a wide range of agricultural, industrial, building, pharmaceutical and / or personal care products and, applications.

A high density, generally recognized as safe hybrid rocket motor is described which has a density-specific impulse similar to a solid rocket motor, with good performance approaching or equal to a liquid rocket motor. These high density hybrid motors resolve the packaging efficiency / effectiveness problems limiting the application of safe, low cost hybrid motor technology.

The present invention relates to a thermophilic arabinose isomerase and a method of manufacturing tagatose using the same, and more precisely, a gene encoding arabinose isomerase originating from the thermophilic Thermotoga neapolitana DSM 5068, a recombinant expression vector containing the gene, a method of preparing a food grade thermophilic arabinose isomerase from the recombinant GRAS (Generally Recognized As Safe) strain transformed with the said expression vector, and a method of preparing tagatose from galactose using the said enzyme.

The invention aims to provide alpha amylase and an aspergillus niger strain for expressing the same. An amino acid sequence of alpha amylase is SEQ ID NO:1. A coding mRNA (messenger ribonucleic acid) sequence of alpha amylase is SEQ ID NO:2. The mutant strain aspergillus niger 1-B5 obtained by an ultraviolet mutagenesis method can efficiently express alpha amylase AclaP11 derived from aspergillus clavatus, with strain number of CGMCC (China General Microbiological Culture Collection Center) No.8443. The enzyme activity of aspergillus niger 1-B5 is 1.97 times that of an original strain. The optimum pH value and optimum temperature of alpha amylase AclaP11 expressed by aspergillus niger 1-B5 are respectively 6.0 and 50 DEG C. Compared with the original strain, aspergillus niger 1-B5 has the advantage that the enzymatic properties are not changed. Besides, aspergillus niger 1-B5 is a food safety fungus (GRAS(generally recognized as safe)), so that alpha amylase expressed by aspergillus niger 1-B5 in a secretory manner can be applied to the field of food additives, thus further broadening the market space of alpha amylase.

A chemical formulation for treating coolant deficiencies, such as corrosion, scale, and low thermal transfer, and treating the root of most of the problems, which is water composition, and providing for preventative measures that further protect the systems that utilize the coolant. The formulation utilizes multiple ingredients, including an adsorbent, an emulsifier, a buffering agent, a dispersant, a deflocculate, a chelation agent, and a peptizing agent, each of which are chosen for a specific task and for the characteristics of having little or no impact on the environment, and for being either a food type additive, approved for use on food preparation surfaces, or otherwise generally recognized as safe. The ingredients, besides having their own specific task, when C compounded with each other in the formulation or those elements found in the system being treated, also provide synergistic effects. All of these elements work together to produce a coolant treatment formulation that is safe to use, that is environmentally compatible, that is effective in both cleaning and protecting the treated system.

The invention discloses a chondroitin producing genetic engineering bacterium, a method for constructing the same and application of the chondroitin producing genetic engineering bacterium, and belongs to the technical field of genetic engineering. Chondroitin synthetase genes and UDP (uridine diphosphate)-glucosamine isomerase genes are transferred into corynebacterium glutamicum to obtain the chondroitin producing genetic engineering bacterium. The chondroitin producing genetic engineering bacterium, the method and the application have the advantages that the corynebacterium glutamicum is used as a host for the chondroitin producing genetic engineering bacterium, is a GRAS (generally recognized as safe) strain affirmed by the Food and Drug Administration of the America, does not secreteoptional endotoxin or exotoxin, is safe and can be applied to producing amino acid or food additives and the like for a long term, and chondroitin produced by the chondroitin producing genetic engineering bacterium is high in molecular weight and good in yield; the chondroitin yield of preferable recombinant bacteria of the chondroitin producing genetic engineering bacterium can reach 3.7 g / L, chondroitin products with high molecular weights can be produced by the chondroitin producing genetic engineering bacterium, and accordingly the chondroitin producing genetic engineering bacterium has anexcellent industrial prospect and can be effectively applied to medicines and health protection.

The present invention provides a process for producing a composition containing a high concentration of aglucone isoflavones, which comprises adding glucone isoflavones to the fermentation of microorganisms which are generally recognized as safe, and can express or produce β-glycosidase on a soy-based substrate. The present invention also provides a composition containing a high concentration of aglucone isoflavones produced in accordance with the process of the invention.

The present invention relates to a recombinant GRAS (Generally Recognized As Safe) strains expressing thermophilic arabinose isomerase as an active form and method of food grade tagatose by using the same, and more precisely, a gene encoding arabinose isomerase originating from the thermophilic Geobacillus stearothermophilus DSM22 and Geobacillus thermodenitrificans, a recombinant expression vector containing the gene, a recombinant GRAS strains expressing the thermophilic arabinose isomerase as an active form by transformed with the expression vector, and a method of preparing food grade tagatose from galactose by using the same.

The Federal EPA has consistently limited the use of known toxicants (insecticides) to preclude their admixture into paints and coatings by contractors or homeowners for the purpose of repelling or killing insects on the dried or cured coating. The current invention is a method to repel rather than kill insects, arachnids, and other arthropods utilizing materials taken from the EPA's GRAS (Generally Recognized as Safe) List, obviating onerous Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) regulations and greatly extends the useful life of the insect-repellant materials by binding them into the dried film solids—greatly slowing their evaporation and degradation and creating a timed release of insect repellant material. Furthermore, the current invention utilizes the insect repellant nature of these materials to repel insects from the surrounding area during coating application, thereby eliminating the need for applying insect repellants such as DEET to the skin.

This disclosure provides generally for antimicrobial compositions and methods for reducing or preventing microorganism growth, viability, or survival, which are useful for treating poultry, meat, seafood, vegetables, legumes, fruit, crops, and other products for human or animal consumption. For example, the compositions can include GRAS (Generally Recognized As Safe) antimicrobial components such as ε-poly-L-lysine in combination with at least one quaternary ammonium salt, including an aliphatic heteroaryl ammonium salt such as cetylpyridinium chloride.

A protein (xylanase) has been identified that produces a strong immune response in pigs when added to a vaccine. The protein is added to vaccines at a particular concentration. The protein is delivered to the animal as part of the vaccine and elicits an immune reaction (antibodies are generated by the animal against the compliance marker protein). The antibodies are then detected in sera samples by a diagnostic test, enzyme-linked immunosorbent assay (ELISA). In the ELISA compliance marker assay, the marker protein (antigen) in coated onto polystyrene plates and is used to detect antibodies against the marker in sera samples. This combination of marker protein added to vaccines and the ELISA to detect antibodies raised against the marker protein can be used to determine whether a particular animal(s) has been vaccinated. The selected protein is commercially-available, identified as Generally Recognized as Safe by the FDA, and does not cause adverse reactions in animals.

Provided are biocide compositions and bleach compositions comprising organic acyl polyoxychlorine and related methods. The reduction of the acyl polyoxychlorine group releases a reactive intermediate that undergoes a series of cascading reduction steps, resulting in termination products Generally Recognized As Safe.

A means for the extraction and crystallization of quassinoids such as quassin and neoquassin from natural sources containing these compounds, using compounds that are Generally Recognized As Safe by the U.S. Food and Drug Administration is provided. In particular, a means for extraction that does not require use of lead acetate, chloroform, methanol, or diethyl ether is provided. The process includes a means of removing non-polar and very polar substances from an extracted residue to enhance crystallization of quassinoids from the residue.

This disclosure provides generally for antimicrobial compositions and methods for reducing or preventing microorganism growth, viability, or survival, which are useful for treating poultry, meat, seafood, vegetables, legumes, fruit, crops, and other products for human or animal consumption. For example, the compositions can include GRAS (Generally Recognized As Safe) antimicrobial components such as ε-poly-L-lysine in combination with at least one quaternary ammonium salt, including an aliphatic heteroaryl ammonium salt such as cetylpyridinium chloride.

A means for the extraction and crystallization of quassinoids such as quassin and neoquassin from natural sources containing these compounds, using compounds that are Generally Recognized As Safe by the U.S. Food and Drug Administration is provided. In particular, a means for extraction that does not require use of lead acetate, chloroform, methanol, or diethyl ether is provided. The process includes a means of removing non-polar and very polar substances from an extracted residue to enhance crystallization of quassinoids from the residue.

The invention discloses a high-efficiency mosquito-repelling skin care lotion and a preparation method thereof. The high-efficiency mosquito-repelling skin care lotion is characterized by consisting of the following raw materials: 3-5 percent of 10-20 percent of hydroxycitronellal 1,2-propanediol acetal, 2-5 percent of geranium extract, 5-10 percent of honey, 5-10 percent of egg white, 0.5-2 percent of Chinese angelica, 0.5-2 percent of peach kernel, 0.5-2 percent of salvia miltiorrhiza, 0.5-2 percent of radix angelicae, 0.5-2 percent of rhizoma typhonii, 0.5-2 percent of rhizoma bletillae and the balance of water. The preparation method comprises the following steps: adding water into the traditional Chinese medicine components for decocting, concentrating and cooling; and adding water into the egg white for diluting, mixing with the traditional Chinese medicine component concentrated solution, adding the 3-5 percent of 10-20 percent of hydroxycitronellal 1,2-propanediol acetal for emulsifying and forming. Compared with a conventional mosquito-repelling product, the mosquito-repelling emulsion has the high-efficiency and long-lasting beneficial effects, has the skin care and beauty effect and integrates the effects of repelling mosquitoes, relieving itching, protecting the skin and beautifying. Moreover, by adoption of the nontoxic raw materials which pass through GRAS (Generally Recognized as Safe) authentication, the product is safe and reliable.

The invention discloses a Pediococcus pentosaceus strain and application thereof. The collection number of the Pediococcus pentosaceus CS1406 is CCTCC NO:M2015169. The strain can be fermented or the free cell of the strain can biotransform para-benzoquinone glucoside in the wheat embryo, thereby producing the 2,6-dimethoxy para-benzoquinone. The Pediococcus pentosaceus CS1406 is derived from the traditional natural fermentation food, and belongs to a microbe generally recognized as safe. The strain can be easily cultured and preserved. The 2,6-dimethoxy para-benzoquinone obtained by wheat embryo fermentation is 942.1 mu g / g. The Pediococcus pentosaceus strain provides a new way for enhancing bioavailability of the wheat embryo, has important application prospects.

The present invention relates to methods for producing water soluble oil palm leaf powder and concentrate. The most preferred method includes the steps of (a) cleaning the leaves with water or an acid with pH lower than 5.5 and salts to produce an extract, (b) extracting the oil palm leaves with a solvent which has polarity index above 2.5 such as methanol, ethanol or ethyl acetate or any combination thereof, especially catechins or ethanol and water which are generally recognized as safe (GRAS) for food consumption (c) filtering and / or centrifuging the extract, (d) sterilizing the extract and (e) microencapsulating the extract from step (d) to form the water soluble oil palm leaf powder and concentrate.

An inexpensive, stereoselective synthesis for nootkatone, tetrahydronootkatone, and their derivatives is disclosed utilizing ozonolysis. The starting materials used in the synthesis are inexpensive and the reactions are commercially feasible and amenable to scaling up. The principal starting material, (-)-[beta]-Pinene, is on the GRAS list (generally recognized as safe).