19results about "Preparation by ozonolysis" patented technology

The invention discloses a preparation method of halogenated acrolein, which comprises the following steps: a compound shown as a formula V is prepared into a compound shown as a formula I under the combined action of a catalyst and an oxidizing agent, and the synthesis route is as follows: # imgabs0 #, and X is halogen. The method for preparing halogenated acrolein disclosed by the invention is mild in condition, high in yield and easy to industrialize. The invention further discloses application of the compound shown in the formula I in preparation of isoxazole, 2-hydroxypyrimidine and homopiperazine.

Systems and methods are provided for ozonolysis of polycyclic aromatic hydrocarbons (PAHs) in a liquid CO2 reaction environment. It has been unexpectedly discovered that oxygen-containing functional groups can be added to PAH substrates while substantially avoiding combustion reactions and while reducing or minimizing formation of energetic intermediates. Because the formation of energetic intermediates is minimal, the ozonolysis can be performed at temperatures near ambient (e.g., between −10° C. and 50° C.) while still achieving a satisfactory safety profile. In various aspects, ozonolysis can occur while forming a reduced or minimized amount of water, such as forming substantially no water in the reaction environment.

Disclosed in the present invention is a method for synthesizing dopamine hydrochloride from eugenol. Environmentally friendly and cheap eugenol is used as a raw material, and is subjected to four steps of methylation, oxidation, reductive amination and acidolysis to synthesize dopamine hydrochloride. Compared with an existing synthesis scheme, the method of the present invention has the advantages of having a low cost, a high yield, being simple to operate and having mild reaction conditions; in addition, the method is environmentally friendly, only one organic solvent may be used during the reaction process, and by-products generated in the reaction can be recovered and reused, thereby facilitating large-scale production of dopamine hydrochloride.

The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I). More particularly, it concerns valuable new chemical intermediates for producing perfuming ingredients. Moreover, the present invention also comprises a process for producing compounds of formula (I).

The present invention relates to the field of organic synthesis, more specifically to a method for preparing a compound of formula (I). Compounds of formula (V), compounds of formula (VI) and compounds of formula (VIII) are also part of the present invention.

The invention relates to the technical field of manganese oxide catalysts, in particular to a SiO2-loaded rare earth-doped Mn oxide catalyst as well as preparation and application thereof. The SiO2 loaded rare earth doped Mn oxide catalyst provided by the invention has a large number of surface oxygen holes, and can convert herbal lignin into high value-added aromatic aldehydes such as p-hydroxybenzaldehyde, vanillin and the like at high selectivity and high conversion rate under mild conditions; rare earth elements and Mn in the crystal structure of the catalyst interact to improve the activity of the catalyst, and furthermore, insufficient exposure of an active center caused by agglomeration of the catalyst is avoided through loading of SiO2, so that the reaction selectivity is effectively ensured, and the reaction efficiency is improved.

The present invention discloses a method for preparing benzaldehyde and anisaldehyde by steam distillation and gas-phase ozone catalytic oxidation of cinnamaldehyde and anethole, comprising the following steps: (1) introducing water vapor and ozone mixed gas into a distillation kettle containing cinnamon branches and leaves, star anise branches and leaves, or star anise fruits, and extracting cinnamon oil or anise oil with the mixed vapor and ozone mixed gas to undergo homogeneous oxidation reaction in a gas channel; (2) directly introducing water vapor and ozone mixed gas into a re-distillation tank containing a cinnamic aldehyde or anethole aqueous solution to carry out gas-phase oxidation reaction; (3) condensing and separating the oxidized vapor to obtain an oil phase containing benzaldehyde or anisaldehyde, and purifying the oil phase by normal pressure or vacuum steam distillation in a distillation tower to obtain benzaldehyde and anisaldehyde. The process of the present invention directly performs gas-phase homogeneous ozone oxidation from the distillation extraction process of branches and leaves, and the oxidation product does not need to be reduced. The product is purified by steam distillation, and the process route is short, energy-saving, and equipment investment is small, which is environmentally friendly.

A new and improved method for preparing maxacalcitol and an intermediate therefor is provided. The method is an efficient and cost-effective process for preparing maxacalcitol and an intermediate therefor.

The invention relates to a method for preparing vanillin by oxidizing ferulic acid with ozone in one step, which comprises the following steps: adding ferulic acid into a two-phase solvent system consisting of an organic solvent and water, starting stirring, controlling a certain temperature, and then introducing ozone for reaction; tracking the reaction by adopting thin-layer chromatography and liquid chromatography, and ending the reaction when the vanillin yield reaches the highest point; introducing nitrogen to remove redundant ozone, separating out an organic layer, washing off a small amount of hydrogen peroxide generated by reaction in the organic layer with water, and recovering the solvent to obtain the vanillin. Compared with the prior art, the method disclosed by the invention is green and environment-friendly, simple in process, mild in reaction condition and high in production efficiency, and provides a better way for producing vanillin by taking ferulic acid as a raw material in industry.

The present invention relates to the field of organic synthesis and more specifically it concerns a process for preparing compound of formula (I). More particularly, it concerns valuable new chemical intermediates for producing perfuming ingredients. Moreover, the present invention also comprises a process for producing compounds of formula (I).

The invention relates to a method for preparing aromatic aldehyde by degrading lignin, which comprises the following steps: firstly, extracting lignin from different sources by an organic solvent method, dissolving the lignin in an organic solvent containing an acidic additive, introducing ozone to carry out ozone oxidative degradation, and then reducing ozone oxide by adopting a reducing agent aqueous solution to obtain the aromatic aldehyde. Finally, the lignin is converted into aromatic aldehyde compounds such as p-hydroxy benzaldehyde, vanillin and syringaldehyde. Compared with the prior art, the method has the advantages that the operation is simple and convenient, the reaction condition is mild, and the method is green and environment-friendly; acid is added into a reaction system, so that the lignin conversion rate and the aromatic aldehyde selectivity are effectively improved. The invention provides a new thought for efficient utilization of lignin, and also provides a feasible technical route for production of high-added-value chemicals.

The present invention discloses a 1,4-dicarbonyl compound, its preparation method and application. The 1,4-dicarbonyl compound has the structure shown in Formula I. The preparation method includes the following steps: S1. Compound a reacts with thionyl chloride and dimethylamine hydrochloride to form compound b; S2. Compound b reacts with iodine, magnesium chips and 4-bromo-1-butene to form compound c; S3. Compound c reacts with dimethyl sulfide to obtain the compound with the structure shown in Formula I. Among them, the preparation method of the 1,4-dicarbonyl compound of the present invention is simple in operation and relatively mild in reaction conditions, and has broad application prospects.

The present invention provides a novel method for producing 1,9-nonane diol, with which 1,9-nonane diol can be efficiently produced with little environmental burden. This method for producing 1,9-nonane diol includes: (1) a step for blowing ozone gas into oleyl alcohol in such a way that ozone gas is blown until the ozone gas concentration at an outlet exceeds half the ozone gas concentration at an inlet, and the acid value of a treated product that has been treated with the ozone gas is 15 mg KOH / g or less; and (2) a step for hydrogenating, in the presence of a nickel catalyst, the treated product that has been treated with the ozone gas.

The invention relates to the technical field of organic matter synthesis, in particular to a novel process for synthesizing isolongifolanone, which comprises the following steps: pouring phosphorus pentoxide, phosphoric acid and acetic acid into a reaction kettle, heating to a preset temperature, and mixing and stirring; slowly adding longifolene into the reaction kettle under the conditions of maintaining constant temperature and stirring, carrying out isomerization reaction, and separating to obtain an isolongifolene mixed solution; and connecting the ozone gas washing bottle with an ozone generator, continuously introducing ozone to promote the oxidation reaction of isolongifolene, and separating to obtain an isolongifolanone mixed solution. Phosphorus pentoxide, phosphoric acid and acetic acid are used as catalysts for isomerism of longifolene, the states of the catalysts are changed through the proper proportion of the phosphorus pentoxide, the phosphoric acid and the acetic acid to form polyphosphoric acid, the polyphosphoric acid and isolongifolene are not dissolved mutually, generation of separation waste water is greatly reduced, the separated polyphosphoric acid can be continuously used only by adding a small amount of consumptions, and the production cost is reduced. And the raw material cost and the separation cost of isomerization are reduced.

The invention relates to the technical field of organic synthesis, in particular to a cerium-manganese bimetallic catalyst, preparation of the cerium-manganese bimetallic catalyst and application of the cerium-manganese bimetallic catalyst in catalyzing ozonized lignin to be converted into aromatic aldehyde. The cerium-manganese bimetallic catalyst provided by the invention has a large number of surface oxygen holes, and can convert herbal lignin into high-added-value aromatic aldehydes such as p-hydroxybenzaldehyde, vanillin and the like at high selectivity and high conversion rate under mild conditions; the catalytic system has good catalytic stability and substrate applicability. Compared with the prior art, under the action of the cerium-manganese bimetallic catalyst provided by the invention, the conversion rate of lignin and the selectivity of high-added-value aromatic aldehyde are remarkably improved; meanwhile, the catalyst is simple to prepare, wide in raw material source, stable and easy to store; when the catalyst is used for preparing high-added-value aromatic aldehyde through conversion of herbal lignin, the catalyst has high selectivity and high activity under mild conditions, and has good application value.

The present invention relates to the field of organic synthesis, more specifically to a method for preparing a compound of formula (I). Compounds of formula (V), compounds of formula (VI) and compounds of formula (VIII) are also part of the present invention.

The present disclosure pertains to improved methods of performing ozonolysis by reductive quenching of the intermediate ozonides using glyoxal as the reductant.

The present invention proposes a method for preparing oxygen-18 methanol, comprising the following steps: ethylene and an oxidant react with heavy oxygen water H2 in an absorber. 18 O contact, and is oxidized to 18 O formaldehyde and formic acid, then add an appropriate amount of reducing agent to reduce oxygen 18 formaldehyde and oxygen 18 formic acid to oxygen 18 methanol, and finally purify the aqueous solution by distillation to obtain high-purity oxygen 18 methanol CH3 18 OH products. Among them, the oxidant used in the ethylene oxidation process is 18 O3, produced by an ozone generator using pure 18 O2 is used as raw material for preparation, and the reducing agent used in the reduction process is one or more of sodium hydride, lithium aluminum hydride or sodium borohydride. 18 O2 as raw material, heavy oxygen water H2 18 O is the solvent, and the whole process does not contain 16 O materials to ensure the abundance of the product. At the same time, the overall reaction conditions are mild and the reaction can be carried out at lower temperature and pressure. The process is simple, highly operable and has good economic benefits.