258 results about "Vanillin" patented technology

The invention belongs to the technical field of food fermentation production, and particularly relates to amycolatopsis thermophilus and application thereof. The amycolatopsis thermophilus is H-1 and is preserved in the China General Microbiological Culture Collection Center (CGMCC) on October 13, 2025, the preservation number is CGMCC No.36166, the classification name of the amycolatopsis thermophilus is Amycolatopsis thermophilus, and the preservation address of the amycolatopsis thermophilus is Beijing, China. The invention also discloses an application of the amycolatopsis thermophilus in preparation of vanillin. The highest yield of vanillin obtained by using the strain reaches 21.6 g / L.

The invention discloses a solvent-free vanillin-hydroxyethyl acrylate double-system closed waterborne polyurethane emulsion adhesive as well as a preparation method and a use method thereof, and belongs to the field of waterborne polyurethane emulsion adhesives. The invention is mainly prepared from the following components in parts by weight: 40 to 50 parts of soft segment monomer, 50 to 60 parts of hard segment monomer, 20 to 40 parts of sealing agent, 0.02 to 0.15 part of catalyst, 0.4 to 0.6 part of emulsifier, 0.2 to 0.6 part of initiator, 4 to 12 parts of neutralizer, 5 to 15 parts of functional monomer and 340 to 360 parts of deionized water. According to the double-system closed waterborne polyurethane emulsion adhesive disclosed by the invention, rapid crosslinking curing of the adhesive can be realized through thermocuring, the highest hardness of an adhesive layer can reach about 26 MPa, the adhesive strength is high, and the mechanical property is relatively good.

The invention belongs to the technical field of high polymer materials, and particularly discloses a lignin-based charring agent containing silicon and nitrogen flame-retardant elements and an imine structure for flame-retardant polylactic acid and a preparation method of the lignin-based charring agent. The flame-retardant polylactic acid is prepared from the following components in parts by weight: 90 to 97 parts of polylactic acid, 1 to 3.33 parts of lignin-based charring agent and 2 to 6.67 parts of ammonium polyphosphate. The bio-based charring agent disclosed by the invention contains silicon and nitrogen flame-retardant elements and an imine structure, has remarkable charring and flame-retardant effects, is high in charring capacity, and can endow the PLA with relatively good flame-retardant property by compounding with ammonium polyphosphate and adding 1% of the lignin-based charring agent; the lignin and vanillin which are used as main raw materials for synthesizing the charring agent are bio-based sources and are easy to obtain, the production process is simple, industrial production is easy, the preparation process is non-toxic and environment-friendly, the dependence of charring agent synthesis on petroleum-based raw materials can be effectively relieved, and the sustainable development trend of materials is met.

The invention belongs to the technical field of artificial veneers, and particularly relates to a fragrance-releasing blue-light-resistant microcapsule and a preparation method thereof, impregnated bond paper of the fragrance-releasing blue-light-resistant microcapsule, a fragrance-releasing blue-light-resistant ecological board and a preparation method of the fragrance-releasing blue-light-resistant ecological board. The technology aims at solving the problems of indoor blue light harm and air quality, and the problems that in the prior art, stable coexistence of a fragrance releasing component and an anti-blue-light component is difficult, and the technology is not compatible. The core is to prepare a multifunctional microcapsule through a unique interfacial polymerization and Schiff base in-situ reaction synchronous process: compound plant essential oil is taken as a core material, a vanillin-polyethyleneimine Schiff base conjugated structure is generated in situ in a wall material, and nanoparticles are cross-linked and fixed, so that a polyurethane / polyurea wall material is formed. The microcapsule is added into an adhesive layer of impregnated bond paper, and then is compounded with a base material through hot pressing to prepare the ecological board. The fragrance releasing and blue light resisting functions are successfully integrated on the board body, the effects that the blue light absorptivity at the wave band of 400-450 nm is larger than or equal to 70%, the formaldehyde release amount is smaller than or equal to 0.025 mg / m, and the fragrance is lasting are achieved, and the technology is highly compatible with an existing production line.

The invention belongs to the technical field of high polymer materials, and discloses a bio-based spiral macromolecular flame retardant as well as a preparation method and application thereof. The novel bio-based spiral macromolecular flame retardant PDVPA is successfully prepared on the basis of common industrial raw materials in combination with bio-based renewable vanillin, and the novel bio-based spiral macromolecular flame retardant PDVPA is applied to preparation of a flame-retardant TPEE composite material by adopting a melt blending process. The phosphorus element in the PDVPA molecular structure is used as a main flame-retardant functional group, and can promote the charring of the spiral structure of the PDVPA molecular structure; meanwhile, an imine bond can be subjected to a trimerization reaction under a high-temperature condition to form a cross-linked network structure, so that the molten drop phenomenon during TPEE combustion is effectively inhibited. The invention provides a new way for improving the safety performance of the high polymer material and reducing the dependence on fossil resources.

The invention relates to the technical field of flame-retardant materials, and particularly discloses a full-bio-based reactive flame retardant, a zero-VOC bio-based basic flame-retardant waterborne polyurethane emulsion and a preparation method of the zero-VOC bio-based basic flame-retardant waterborne polyurethane emulsion. According to the invention, vanillin, lysine and phytic acid are taken as raw materials, a full-bio-based reactive flame retardant is synthesized, and the full-bio-based reactive flame retardant can form chemical bonding with a waterborne polyurethane matrix, so that intrinsic flame retardance is realized. A molecular structure of the cosolvent contains a plurality of high-activity groups such as hydroxyl groups, the cosolvent has excellent thermal stability and lasting flame-retardant efficiency, can be chemically bonded with a waterborne polyurethane matrix under a low-temperature condition, remarkably reduces the dosage of the cosolvent, and can realize zero VOC solvent emission when being applied to a chemical flame-retardant modification process of waterborne polyurethane. Meanwhile, the Schiff base group contained in the flame retardant endows the flame retardant with an extra antibacterial function, breeding of microorganisms on the surface and inside of the material can be inhibited after the flame retardant is combined with waterborne polyurethane, material degradation caused by microbial erosion is avoided, the service life of the material is prolonged, and the using effect of the material is improved.

The invention discloses a gel microneedle loaded with silver nanoparticles and a preparation method and application thereof.The extract nano-silver (AB-AgNPs) is prepared through a green synthesis strategy, a drug-loaded microneedle system is constructed based on carboxymethyl chitosan-vanillic aldehyde-polyvinyl alcohol (CMCS-Va-PVA) composite gel, the AB-AgNPs prepared through the technology are uniform in particle size and stable in dispersion, and the drug-loaded microneedle has the advantages that the drug-loaded microneedle is good in drug-loaded performance and good in drug-loaded performance; the crystal has a typical face-centered cubic crystal structure and metal state Ag0 characteristics; the gel microneedle has good mechanical strength and forming effect, the AB-AgNPs and the gel matrix are stably combined through hydrogen bonds, the chemical properties are kept unchanged, and the system has broad-spectrum efficient bacteriostatic activity and biocompatibility; an in-vitro experiment proves that the green synthesized gel microneedle loaded with the silver nanoparticles has a remarkable capability of promoting the healing of L929 cell tissues; a rat wound experiment proves that the gel microneedle can regulate and control an inflammatory factor network and promote cell migration and tissue regeneration, healing of common and infected wounds is remarkably accelerated, and the wound residue ratio in 9 days is as low as 2.7% and 10.9% respectively.

This invention discloses a biomass-based aerogel for fruit cushioning packaging and its preparation method, belonging to the technical field of food packaging materials. The preparation steps are as follows: chitosan solution and gelatin solution are mixed, and vanillin is added to carry out a cross-linking reaction to obtain a cross-linked mixture; the cross-linked mixture is subjected to low-temperature pre-freezing treatment, followed by freeze-drying to obtain the biomass-based aerogel for fruit cushioning packaging. The aerogel preparation method provided by this invention is simple, the raw materials are natural and renewable, and the acquisition cost is low. The obtained aerogel possesses excellent mechanical properties and cushioning effect, which is of great significance for the cushioning and storage of fruits during transportation.

The invention discloses a compound vitamin amino acid premix as well as a preparation method and application thereof, and belongs to the technical field of feed additives. An embedding system is formed by the chitosan, the polyethylene glycol and the glyceryl ricinoleate, and the tea tree oil and the perilla oil are compounded to serve as an antioxidant, so that the stability of vitamins can be remarkably improved. Besides, hydroxyapatite is added into the starch, modification treatment is performed through succinic anhydride and polyvinylpyrrolidone, the component compatibility is good, o-vanillin is introduced, the fragrance of o-vanillin has a food calling effect, the palatability is improved, the components of the functional additive are optimized, and the remarkable immune enhancement and growth promotion effects can be achieved; the cellular immunity and humoral immunity functions of the body are enhanced, and the granulating formability is effectively promoted by combining with the components of the carrier with good compatibility. On the whole, through interaction of the vitamin composition, the amino acid composition, the functional additive and the carrier, the immunity and growth performance of animals are jointly improved from multiple aspects.

The present application relates to the field of medicine synthesis, and discloses a preparation method and application of brominated piperonal carboxylic acid, wherein the brominated piperonal carboxylic acid compound is prepared from o-vanillin as a starting material through acetyl protection, bromination reaction, deprotection and demethylation reaction, cyclization reaction and Pinnick oxidation reaction.No longer through a brominated piperonal intermediate, and without using a live LDA reagent low-temperature lithiation reaction, the safety and stability are greatly improved.The deprotection and demethylation reaction is carried out in one pot, and the use of boron tribromide and other reagents is avoided;finally, the oxidation step from aldehyde to acid avoids using traditional silver oxide or potassium permanganate oxidation, and adopts Pinnick oxidation, which is economic, environmental protection and cost reduction, and greatly improves the yield.The whole has the advantages of easy-to-obtain raw materials, short steps, mild reaction conditions, low production cost, environmental protection, high yield and high purity, and can meet the high quality requirements of pharmaceutical products.

The present invention relates to a method for the treatment of keratin fibres comprising the application, to the fibres, of a composition comprising at least one chemical oxidizing agent, at least one (bi)carbonate and at least one silicate, this application being preceded and / or followed by the application, to the keratin fibres, of a composition comprising one or more compounds chosen from organic acids, amino acids, chitosans, vitamins B, vitamin C, vanillin, their salts, their solvates and their mixtures.

The invention belongs to the technical field of hot melt adhesive films, and particularly relates to a hot melt adhesive film with high bonding strength and a preparation method thereof. The preparation method comprises the following steps: (1) mixing o-vanillin double five-membered cyclic carbonate and phosphorus-containing diamine, and carrying out polymerization reaction under a heating condition to obtain a prepolymer; and (2) carrying out vacuum defoaming treatment on the prepolymer, then coating to form a film, curing, cooling and stripping to obtain the film. An o-vanillin bio-based rigid framework and a Schiff base bond structure in the o-vanillin bio-based rigid framework are used for enhancing cohesive energy and interface interaction, and meanwhile, phosphorus is introduced into a polymer main chain in a covalent bond mode, so that intrinsic flame retardance is achieved. The obtained hot melt adhesive film has high tensile strength, high bonding strength, excellent flame retardance and good heat resistance and water resistance.

The invention belongs to the technical field of polyamide materials, and discloses a novel bio-based polyamide and a preparation method thereof, and the bio-based polyamide material has a structure as shown in formula (1). The bio-based polyamide is prepared through simple and efficient Knoevenagel condensation reaction of a vanillin derivative dialdehyde group monomer and a binary cyano amide monomer, the polymerization temperature ranges from 160 DEG C to 200 DEG C, and the polymerization time ranges from 1 h to 3 h. The bio-based polyamide prepared through the method is good in mechanical property, the breaking strength can reach 50-80 MPa, the elongation at break ranges from 100% to 400%, and the bio-based polyamide has good acid and alkali resistance and solvent resistance. The method provides an efficient, environment-friendly and economical solution for preparation of polyamide. Formula (1); wherein x is 3-18, and y is 3-18.

The invention discloses an antibacterial and hydrophilic dual-functional ionic liquid double-layer membrane as well as a preparation method and application thereof. According to the double-layer film, corn starch (ST) and polyvinyl alcohol (PVA) serve as substrates, and natural dye alizarin (AL) is mixed to serve as a hydrophilic layer; chitosan (CS), corn protein (Zein) and vanillin (VA) serve as a supporting layer; meanwhile, the ionic liquid is doped, so that the double-layer film is endowed with a fresh-keeping function and sensitive detection capability, the limitation of a single detection function is broken through, and a new thought is provided for food safety.

The invention provides a prebiotic milk tea solid beverage and a preparation method thereof. Comprising the following steps: (1) preparing fiber mesh powder coated with probiotic spores; (2) preparing immobilized yeast gel microspheres; (3) drying the gel microspheres in a fluidized bed, and spraying a coating solution until the weight of the microspheres is increased by 18% to obtain immobilized yeast microspheres; (4) mixing the fiber mesh powder coated with the probiotic spores, the immobilized yeast microspheres, MCT powder and vanillin to obtain mixed powder; and putting the mixed powder into a fluidized bed, spraying a binder, and granulating until the particle size is 200-300 microns and the water content is 4.3-4.5%, thereby obtaining the prebiotic milk tea solid beverage. According to the invention, four functional factors of prebiotics (GOS / FOS), probiotics (lactobacillus spores and yeast), high protein and tea polyphenol are integrated, and 1 + 1gt among the functional factors is realized through cascade reaction of yeast metabolism, spore activation and bacterial enzyme synergism; 2, through the synergistic effect, the intestinal flora balance and the body metabolism health are jointly regulated;

The invention discloses a biphase gel capable of reducing salt of the gel and a preparation method of the biphase gel, and belongs to the fields of food nutrition and health, food packaging and biological medicine. The stable hydrogel is constructed through a special network structure generated through special hydrogen bond interaction and electrostatic interaction among starch, chitosan, glycine betaine, vanillin and sodium chloride and induction of a Schiff base cross-linked structure of the starch, the chitosan, the glycine betaine, the vanillin and the sodium chloride; the monoglyceride and soybean oil crystals are self-assembled to form stable oil gel; and mixing and homogenizing the hydrogel and the oil gel. The prepared two-phase gel can realize sustained and controlled release of sodium, the salty taste retention time and the salty taste perception are enhanced, and the method is simple, green, pollution-free and low in energy consumption.

The invention discloses a piglet anti-diarrhea complete feed formula based on a microecological preparation, and relates to the technical field of animal nutrition and health. The microsphere has a unique three-layer core-shell structure, wherein a core layer is coated with butyric acid producing probiotics and precise prebiotics; the middle layer is a chitosan-gallic acid-vanillin terpolymer with dual functions of strong mucous membrane adsorbability and quorum sensing quenching; and the shell layer is a pH-sensitive slow-release coating and is loaded with an acidifying agent. The structure is constructed through a layer-by-layer coating process, and the technical problems that in the prior art, functional components cannot be delivered in a targeted mode, the synergistic effect is poor, and intestinal barriers cannot be actively repaired are solved. When the microspheres enter animal digestive tracts, the shell layer firstly releases an acidifying agent at the front end to inhibit pathogenic bacteria and clear obstacles for subsequent steps; after entering the small intestine, the middle layer polymer is released, adheres and repairs the damaged intestinal mucosa in the form of a biological bandage, and interferes pathogen communication at the same time.

The invention relates to the technical field of organic synthesis, in particular to a one-pot method for preparing vanillin by taking eugenol as a raw material, which comprises the following steps: (a) mixing eugenol and a compound additive according to a mass ratio of 1: (0.2-0.5), and uniformly stirring to obtain a premix; (b) adding an oxidizing agent into the premix, and carrying out primary oxidation reaction at 40-60 DEG C for 30-60 minutes to obtain an intermediate product; (c) adding a supported catalyst into the intermediate product, and carrying out oxidation reaction at 80-100 DEG C for 2-4 hours to obtain an oxidation reaction solution; (d) cooling the oxidation reaction liquid to room temperature, removing the catalyst through centrifugal separation, and collecting a liquid layer; and (e) carrying out reduced pressure distillation on the liquid layer, and collecting fractions to obtain vanillin. According to the scheme, through the synergistic effect of the compound additive, the staged oxidizing agent and the supported catalyst, an efficient conversion molecule-interface-catalytic system is constructed, and high purity and high yield are obtained.

The application belongs to the technical field of medicine and pharmacy, and particularly relates to application of vanillin in preparation of a Klebsiella pneumoniae capsule inhibitor. The application relates to application of vanillin in preparation of an inhibitor for inhibiting formation, adhesion or function of a Klebsiella pneumoniae capsule, and related antibacterial or anti-infection products, wherein the vanillin reduces pathogenicity of Klebsiella pneumoniae by inhibiting capsule synthesis. It is disclosed that the vanillin can effectively inhibit formation of a Klebsiella pneumoniae capsule and reduce viscosity of bacteria, and can effectively treat mice infected with Klebsiella pneumoniae.

This invention relates to an intrinsically flame-retardant bio-based epoxy resin and its preparation method, belonging to the field of polymer materials technology. Using vanillin and chitosan as main raw materials, the invention first involves an oxidative coupling reaction of vanillin to construct a divanillin compound with a dual aromatic structure. Subsequently, the divanillin compound with the dual aromatic structure and chitosan are introduced into the epoxy resin structure via a one-pot reaction to synthesize a chitosan-based vanillin epoxy resin. After curing, a cross-linked network containing aromatic and Schiff base structures is formed, thereby endowing the material with intrinsic flame-retardant properties. In the UL-94 vertical burning test, it achieves a V-0 or V-1 rating, exhibiting excellent flame-retardant effects and overcoming the problems of traditional epoxy resins, such as reliance on external flame retardants, low flame-retardant efficiency, and deterioration of mechanical properties. The preparation method of this invention is simple, and the cured material possesses both good mechanical properties and excellent flame-retardant properties, showing broad application prospects.

The invention relates to a carboxylic acid reductase (MACAR) from Mycobacterium agri, and the carboxylic acid reductase (MACAR) shows higher substrate conversion efficiency than that of a source NiCAR (NiCAR) from Nocardia iowensis, and is suitable for the conversion production of vanillin from vanillic acid. A systematic process for efficient screening and verification of carboxylate reductase CAR identifies a plurality of novel CARs with potential industrial application values, and lays a foundation for directed evolution and industrial application.

The application discloses a preparation method and application of allulose-vanillin microcapsules, and comprises a double emulsion preparation step, an alternating current field treatment step and a spray drying step. By constructing a double water-in-oil-in-water emulsion, the problems of low solubility and poor stability of the material are solved, and the bioavailability of allulose and vanillin is improved. The allulose-vanillin microcapsules are prepared by using alternating current field superimposed spray drying, the adsorption and combination of allulose and vanillin molecules on the water-oil phase are strengthened, and the encapsulation rate and the retention rate of vanillin are effectively improved. The preparation method provided by the application aims to reduce the sucrose content in food by using cross-modal interaction, realizes the goal of reducing sugar without reducing sweetness of food, solves the problems of insufficient sweetening effect and limited microcapsule embedding efficiency of flavor substances in the prior art, and has a wide market application prospect in the field of food processing.

The application discloses a liquid-phase detection method for curcumin related substances and application thereof, characterized in that the method adopts high performance liquid chromatography, and the chromatographic conditions comprise that a mobile phase A is a 1% mass concentration phosphoric acid aqueous solution; a mobile phase B is acetonitrile; gradient elution is adopted, and the program of the gradient elution is as follows: 0-11 min, the volume percentage of the mobile phase A changes from 60% to 38%; 11-15 min, the volume percentage of the mobile phase A remains 38%; 15-20 min, the volume percentage of the mobile phase A changes from 38% to 30%; and 20-30 min, the volume percentage of the mobile phase A remains 30%. The application can effectively alleviate the problem of unstable baseline caused by curcuminone-enol tautomerism, and can simultaneously separate and detect multiple related substances including vanillin, acetylacetone and ketone isomers, and has the characteristics of high resolution, good specificity and high sensitivity.

The present application relates to the technical field of road engineering materials, in particular to a polymer pavement modifier and a preparation method thereof, the polymer pavement modifier comprises component A composed of epoxy resin, epoxy-based polyurethane, titanate coupling agent and epoxy active diluent, and component B composed of silicon-containing flame-retardant curing agent, amine curing agent, acid anhydride curing agent and accelerator; wherein the epoxy-based polyurethane is obtained by pre-polymerization of diisocyanate after epoxydation of hydroxyl-terminated butadiene rubber, and then chain extension reaction; the silicon-containing flame-retardant curing agent is obtained by reaction of phenylphosphoryl dichloride, vanillin and 1,3-bis(3-aminopropyl)-1,1,3,3-tetramethyldisiloxane in a molar ratio of 1:2:2. The polymer pavement modifier prepared by the present application can effectively improve the performance of asphalt, and is suitable for pavement and repair of steel bridge deck, tunnel, highway and the like, and improves traffic safety.

The invention relates to the technical field of barrier films for cigarettes, in particular to a chitosan / polyvinyl alcohol barrier film and a preparation method thereof. The preparation method comprises the following steps: S1, carrying out Knoevenagel condensation reaction on vanillin and malonic acid in the presence of a catalyst to obtain a product a; mixing and reacting the product a with polyvinyl alcohol to obtain a product b; s2, using carbodiimide to activate malonic acid into an activated intermediate; adding the activated intermediate into the product b and chitosan for reaction to obtain a film forming solution; and S3, preparing the barrier film from the film forming solution. A reaction product of vanillin and malonic acid is used as a cross-linking agent to connect chitosan and polyvinyl alcohol to obtain the barrier film, so that aromatic rings and carbon-carbon double bonds are introduced into a three-dimensional network structure of the barrier film, and hydroxyl, carboxyl, amino and the like react into ester bonds and amido bonds; the tensile property, the water vapor barrier property and the oxygen barrier property of the barrier film are effectively improved.

The invention provides oak chips for ageing high-quality beer as well as a preparation method and application of the oak chips. Every 100 g of the oak sheet is prepared from the following components by mass: 1600 to 15000 mg of vanillin, 750 to 1600 mg of whisky lactone, 4500 to 22500 mg of furfural, 25 to 80 mg of guaiacol, and 55 to 70 mg of eugenol. The preparation method of the oak chips for aging beer comprises the steps of baking treatment and ultraviolet photolysis treatment of raw oak chips, the temperature of the baking treatment is 150-240 DEG C, and the optical power density of the ultraviolet photolysis treatment is 0.6-0.8 W / m < 2 >. The oak chips disclosed by the invention are high in content of phenols and lactones, and high-quality beer which is excellent in balance degree and harmony of various fragrances can be obtained in a short time.

The invention discloses a production method of low-fat custard sauce. The production method comprises the following steps: step S01, raw material pretreatment: preheating skimmed milk, and adding a compound emulsifier to form a milk solution; mixing the modified cassava starch, resistant dextrin and konjac glucomannan, adding purified water, and stirring to prepare starch colloid emulsion; step S02, mixing and gelatinizing: sequentially adding low-fat yolk powder and corn oligopeptide powder into the cow milk solution, stirring and dissolving, slowly injecting starch colloid milk, and carrying out heat preservation and gelatinization; s03, seasoning and homogenizing: adding compound sugar, citric acid, edible salt and vanillin, stirring and dissolving, and homogenizing at high pressure; s04, sterilizing and cooling: quickly cooling after sterilizing; and step S05, filling: filling into a packaging bag, and sealing and storing. Through synergistic thickening of the composite colloid and the modified starch, flavor enhancement of the functional peptides and optimized emulsification and homogenization processes, fat and calorie are remarkably reduced, and meanwhile, the taste and stability of the product are guaranteed.

This invention provides a fully biodegradable pectin-based food packaging film, its preparation method, and its application. The preparation method of the fully biodegradable pectin-based food packaging film includes: Step 1, adding pectin and vanillin to water and dissolving them to obtain a reaction solution; Step 2, adding a catalyst and a plasticizer to the reaction solution and stirring to obtain a film-forming solution; Step 3, shaping the film-forming solution into a film and drying it to obtain a vanillin crosslinked pectin film; Step 4, immersing the vanillin crosslinked pectin film in an aqueous solution containing glycerol and FeCl3, then removing and drying it to obtain the fully biodegradable pectin-based food packaging film. This food packaging film is completely biodegradable, reducing the dependence of food packaging films on non-renewable petroleum products and avoiding environmental pollution caused by incineration.

To suppress fading of food and drink colored with an anthocyanin-based pigment.SOLUTION: An effective amount of at least one kind selected from the group consisting of furaneol, vanillin, maltol, ethyl butyrate, hexyl acetate, trans-2-hexenal, isoamyl acetate, methyl hexanoate, ethyl 2-methyl butyrate, ethyl 3-hydroxyhexanoate, alpha-ionone and damascenone is added to food and drink colored with an anthocyanin-based pigment. In addition, a pigment preparation and a food and drink composition containing the same components are provided.SELECTED DRAWING: None

The invention discloses a diaryl pentane compound as well as a pharmaceutical composition, a preparation method and application thereof, and relates to the technical field of medicines. The preparation method comprises the following steps: reacting vanillin and acetone serving as starting raw materials to generate an (E)-4-(4-hydroxy-3-methoxyphenyl)-3-butene-2-one intermediate, carrying out condensation reaction on the intermediate and a benzaldehyde derivative under an alkaline condition to obtain a conjugated diaryl pentane derivative, and finally, carrying out palladium-carbon catalytic hydrogenation reaction to obtain the 4-(4-hydroxy-3-methoxyphenyl)-3-butene-2-ketone derivative. The target diaryl pentane derivative can be prepared; 3-(4-hydroxy-3-methoxyphenyl) propionic acid and a benzylamine derivative are used as raw materials, the amide diaryl pentane analogue is prepared through an amide condensation reaction, the synthesis process is simple and convenient, and the steps are simple. The diaryl pentane compound prepared by the invention has remarkable alpha-glucosidase inhibitory activity, can effectively reduce the blood sugar level of mice orally taking cane sugar and starch, and has wide application prospects in blood sugar reducing medicines, weight losing medicines and health-care foods with a blood sugar reducing function.