48 results about "Lonicera confusa" patented technology

The invention relates to essence, in particular to flavoring essence used for tobacco. The flavoring essence is formed by mixing the following raw material components in percentage by weight: 1 to 3 percent of 10 percent vanillin, 2 to 4 percent of 10 percent damascenone, 2 to 4 percent of 10 percent ethyl maltol, 5 to 8 percent of stachyurus extract, 2 to 4 percent of Peru concrete, 1 to 3 percent of five-flavor ketone, 0.5 to 2 percent of 10 percent furaneol, 1 to 3 percent of 10 percent oak chip extract, 0.5 to 2 percent of 10 percent cassia leaf oil, 0.5 to 2 percent of elecampane extract, 1 to 3 percent of 10 percent clove bud oil, 2 to 4 percent of Xianning orange osmanthus extract, 1 to 3 percent of 1 percent valerian oil, 1.5 to 3 percent of trigonella tincture, 0.5 to 2 percent of 10 percent geranium oil, 15 to 20 percent of white hyacinth bean tincture, 1 to 3 percent of 10 percent acetic ether, 5 to 8 percent of lonicera confusa extract, 1 to 3 percent of ribes burejeuse extract, 8 to 51.5 percent of 70 percent ethanol, and 1 to 3 percent of daidzein. The flavoring essence used for the tobacco overcomes the defects that the prior cigarette has burr feeling at the throat and astringent feeling at the oral cavity, and has quite obvious effect of improving the comfort of the cigarette.

The invention discloses a method for preparing high purity chlorogenic acid. The method comprises the following steps of: preparing a lonicera confusa extract from lonicera confuse serving as a raw material by using a mixed solvent of ethanol and water under the ultrasonic condition, dissolving the extract in water, selectively extracting chlorogenic acid from the aqueous solution, performing back-extraction on extract liquor by using an aqueous solution of polyacrylamide to remove partial high-polarity impurities, decoloring the extract liquor subjected to back-extraction by using active carbon, and recrystallizing to obtain chlorogenic acid crystals. The method is easy to impellent, the production period is short, the yield and purity of the product are high, and the method is suitable for industrial production.

The invention relates to a medicinal composition of lonicera confusa and a preparation method thereof. The composition is in a pharmaceutically acceptable formulation prepared from lonicera confusa, chrysanthemum, platycodon root, mint, dwarf lilyturf tuber, hawthorn, liquorice and borneol. The composition has the effect of clearing away heat, and detoxicating, and nourishing Yin and tonifying the kidney, and is mainly used for treating the symptoms, such as sore throat caused by acute and chronic pharyngitis and cold fever, and the like. The invention also relates to the preparation method of the medicinal composition. The total effective rate of buccal tablets used for treating acute pharyngitis and prepared from the medicinal composition is up to 95 percent.

The invention discloses lonicera confusa floral water and a preparation method thereof. The lonicera confusa floral water is made of raw materials including, by weight, 700-800 parts of extracting solution, 37-43 parts of dimethyl phthalate, 1.5-1.9 parts of menthol, 0.3-0.7 part of borneol, 18-22 parts of essence, 0.8-1.2 parts of ethylparaben, 175-195 parts of distilled water and 1.8-2.2 parts of ethylene diamine tetraacetic acid. The preparation method includes the steps: preparing the extracting solution; preparing finished lonicera confusa floral water. Lonicera confusa and saxifrage serve as main raw materials and are matched with ethanol with the concentration of 50% to prepare the lonicera confusa floral water, the prepared floral water has the functions of repelling mosquitoes, relieving itching and killing germs and effectively solves the problem of single function of existing floral water, fragrance of the prepared floral water is more uniform as components such as the borneol and the essence are added into a formula, a user feels cool and refreshing when using the floral water, the raw materials of the floral water are easily obtained, the preparation method is simple, and the floral water is low in cost, has the functions of clearing heat, removing toxicity, dispelling wind and heat and has no stimulation to skins.

The invention provides a cool and refreshing beverage prepared from medical and edible dual-purpose Chinese medicinal materials and a preparation method thereof. The cool and refreshing beverage is prepared from lonicera confusa, chrysanthemum, hawthorn, orange peel, an acidity regulator and a thinning agent. The beverage provided by the invention has the effects of clearing away summer heat, helping produce saliva and slake thirst and strengthening spleen and promoting appetite, is suitable for both old people and children and has good social benefits and high economic value.

The invention relates to the field of traditional Chinese medicine prescriptions and in particular to a herba houttuyniae, radix liriopes, lonicera confusa, arisaema cum bile and rhizoma arisaematis powder for early infantile pneumonia. The herba houttuyniae, radix liriopes, lonicera confuse, arisaema cum bile and rhizoma arisaematis powder for the early infantile pneumonia is characterized by comprising the raw materials in percentages by weight: 10-14% of herba houttuyniae, 8-12% of radix liriopes, 6-10% of lonicera confusa, 2-6% of arisaema cum bile, 5-7% of rhizoma arisaematis, 2-6% of burdock, 2-6% of semen lepidii, 5-7% of allium macrostemon, 6-10% of fritillaria cirrhosa, 5-7% of radix astragali, 2-6% of periostracum cicadae, 6-10% of tussilago farfara, 2-5% of rhizoma atractylodis, 2-6% of prepared pinellia tuber, 2-6% of antelope's horn and 6-10% of liquorice. The powder is prepared through the steps of: drying the raw materials and grinding the raw materials into fine powder; sieving by a 120-mesh sieve and bottling for standby application. The herba houttuyniae, radix liriopes, lonicera confusa, arisaema cum bile and rhizoma arisaematis powder for the early infantile pneumonia, disclosed by the invention, has the advantages of low cost, high treatment effect on treating early infantile pneumonia, no untoward effect such as allergic reaction, no toxic and side effects, no drug resistance, functions on diffusing the lung and stopping asthma, eliminating phlegm by cooling, dispelling wind and relieving a cough, nourishing yin and moisturizing lung, promoting blood circulation to remove blood stasis, boosting qi and nourishing yin and strengthening the body resistance to dispel evils and effectiveness on phlegm-heat lung obstructing type, phlegmy-heat lung obstructing type and yin deficiency lung heat type pneumonia diagnosed according to traditional Chinese medical science.

The invention discloses a micro-enema for treating upper respiratory track infection and a preparation method thereof. The micro-enema is prepared from the following raw materials by weight: 10 to 200g of lonicera confusa, 10 to 200g of scutellaria baicalensis, and 10 to 200g of bupleurum. The preparation method comprises the following steps of: decocting and extracting the scutellaria baicalensis, adjusting the pH value of the decocted mixture by using sodium hydroxide solution in each decocting process, mixing the obtained decoction liquid so as to obtain liquid A; adding water into the bupleurum for distillation, collecting distillate produced in the first 30 to 40 minutes so as to obtain liquid B; adding water into the produced dregs of a decoction of the bupleurum and the lonicera confusa for decoction, mixing the obtained two-time decoction liquid and the residual liquid of the bupleurum subjected to distillation, concentrating and filtering the obtained liquid, and adjusting the PH value of the obtained filter liquid so as to obtain liquid C; and finally, mixing 30 to 35 volume percent of liquid A, 5 to 10 volume percent of liquid B and 55 to 60 volume percent of liquid C, and then carrying out separated-loading and sterilization on the obtained liquid so as to obtain the micro-enema. The micro-enema product produced by the method of the invention has the advantages of quick response to and good curative effect on infantile hyperpyretic symptoms and convenient use.

The present invention discloses a diabetes treating traditional Chinese medicine preparation identification method. According to the present invention, the traditional Chinese medicine preparation is prepared from Keyaoluoqu, plantago depressa willd, agrimonia pilosa ledeb, and lonicera confusa dc; the identification is carrying out thin-layer chromatography on Keyaoluoqu, plantago depressa willd, agrimonia pilosa ledeb, and lonicera confusa dc, wherein the Keyaoluoqu identification method is the thin-layer chromatography method adopting a luteoloside reference substance as a control and adopting a mixed solution comprising ethyl acetate, acetone, formic acid and water according to a ratio of 7:3:1:1.2 as a developing solvent, the plantago depressa willd identification method is the thin-layer chromatography method adopting a plantamajoside reference substance as a control and adopting a mixed solution comprising ethyl acetate, acetone, formic acid and water according to a ratio of 7:3:1:1.2 as a developing solvent, the lonicera confusa dc identification method is the thin-layer chromatography method adopting an isochlorogenic acid A reference substance as a control and adopting a mixed solution comprising ethyl acetate, acetone, formic acid and water according to a ratio of 7:3:1:1.2 as a developing solvent; and the identification method of the present invention has characteristics of high sensitivity, good reproducibility, convenience, feasibility, and no negative control interference.

The invention discloses high-nutrient ferment. The high-nutrient ferment comprises smallanthus sonchifolius, pitayas, apples, figs, cashews, Hami melons, watermelons, coconuts, plums, apricots, kiwi fruits, rambutan, litchi, mulberries, strawberries, pomegranates, radishes, needle mushrooms, shiitake mushrooms, arrowhead, broccoli, ginseng, black sesame seeds, semen brassicae junceae, sophora flowers, lonicera confusa, a haw extract, a honeysuckle extract, lycium barbarum polysaccharides, astragalus polysaccharides, a red jujube extract and a codonopsis pilosula extract. Besides, the inventionfurther discloses a preparation method of the high-nutrient ferment. The preparation method comprises three steps of performing pretreatment, performing pre-fermentation and performing fermentation.The ferment prepared by the method can supplement nutrient substances for human bodies, can improve the immunity of human bodies, and cannot cause body weight to be increased obviously after being drunk.

The invention relates to the technical field of candies, in particular to a throat-clearing and lung-moistening functional candy taking Chinese olives as a main material and a preparation method thereof. The candy is prepared from the following materials in parts by weight: 30-450 parts of emblic, 30-450 parts of lonicera confusa, 30-450 parts of Chinese olives, 30-450 parts of licorice, 500-750 parts of granulated sugar, 50-300 parts of glucose, 50-250 parts of maltodextrin, 5-100 parts of vitamin C, 5-100 parts of citric acid, and 0.5-20 parts of menthol. The method comprises: extractum preparation, syrup preparation, mixing, cooling, strip bracing, forming, and packaging. The candy has various functions such as clearing throat, moistening the lung, regulating gastrointestinal tracts, producing liquid to relieve cough, replenishing deficiency, moistening the lung and clearing away heat and toxic materials.

The invention relates to traditional Chinese medicine composition for treating swine infectious atrophic rhinitis. The traditional Chinese medicine composition is prepared by components in parts by weight as follows: 15-35 parts of rheum officinale, 15-35 parts of herba cirsii japonici carbonisatum, 15-35 parts of subprostrate sophora, 15-35 parts of lonicera confusa, 15-45 parts of Chinese yam, 15-35 parts of hawthorn, 15-50 parts of liquorice, 15-45 parts of rhizome nardostachyos, 15-35 parts of herba pyrrosiae, 15-35 parts of salvia chinensis, 15-45 parts of concha haliotidis and 15-35 parts of rhizoma acori graminei. The traditional Chinese medicine composition has the benefits of reasonable formula, simplification of preparation, no toxic or side effects, no pollution, no medicine residues, no medicine resistance, superfine grinding, high bioavailability and obvious curative effect; and clinical tests prove that the composition has a specific effect in treating the swine infectious atrophic rhinitis.

The invention discloses an ecological planting method of Lonicera confusa in the field of Lonicera confusa planting. The method comprises steps as follows: (1) land selection and preparation; (2) seedling planting; (3) topdressing; (4) pruning; (5) disease and pest prevention and control: a, composted organic fertilizer with the mass fraction ratio of nitrogen to phosphorus to potassium being 13:9:10 is adopted; b, insect-plague branches, dead branches, dense branches and weak branches are pruned; c, purified water is sprayed to front surfaces of leaves firstly, then 75% industrial alcohol is atomized and sprayed on back surfaces of the plant leaves, and natural enemies are introduced; d, the insect-plague branches, the dead branches, residues and fallen leaves are burnt in a centralized manner, and disease points are sterilized and filled with pollution-free soil; (6) picking. With the adoption of the scheme, biological prevention and control replace chemical prevention and control, conditions that medicines inside the Lonicera confusa and heavy metal content of the Lonicera confusa exceed the standard are directly reduced, pollution to soil, water sources and the like is avoided, the environment inside a planting area is optimized, and a basic guarantee is provided for excellent quality of the Lonicera confusa.

The invention provides a method for detecting honeysuckle flower and lonicerae flos medicinal materials through rapid resolution liquid chromatography (RRLC). Honeysuckle flowers have the remarkable biological activities of resisting bacteria, inflammations, viruses and the like, and can be widely added into related products such as compound medicines, food and beverages. Due to the fact that the price spread of honeysuckle flowers and lonicerae flos is large, the phenomenon that lonicerae flos is adopted as the main substitutes of honeysuckle flowers for honeysuckle flower product adulterating exists on the market. The method can simultaneously analyze the compounds of chlorogenic acid, galuteolin, macranthoidin B and dipsacoside B contained in honeysuckle flowers and lonicerae flos within 8 min, can be used for identifying honeysuckle flower and lonicerae flos medicinal materials so as to monitor the mass of the honeysuckle flower raw materials and products, and has the good precision, repeatability and accuracy.

The invention discloses a toothpaste formula containing Folium Folium, comprising the following raw materials in parts by weight: 28-40 parts of mint, 8-15 parts of sea salt, 8-20 parts of reed root, 10-18 parts of orange peel, Folium folium 1‑10 parts, 1‑9 parts of lobelia, 10‑20 parts of sweet potato, 2‑8 parts of kudzu flower, 10‑20 parts of red peony, 15‑30 parts of mountain silver flower, 20‑30 parts of stevia, salt 1‑5 servings. The beneficial effects of the present invention are: the combination of the above raw materials produces a good synergistic effect, and the manufactured product has the health-care effects of clearing away heat, fixing teeth, moisturizing, sterilizing, deodorizing, and refreshing breath, and is effective in preventing gum bleeding and gum swelling. Significant effect, while having a relieving effect on minor oral diseases.

The invention discloses a novel odorless and durable freshener, which consists of the following raw material components in parts by weight: 10-20 parts of lonicera confusa, 5-10 parts of polyurethane, 2-8 parts of cyclohexanol, 1-6 parts of wintergreen oil, 3-12 parts of acid amide, 5-10 parts of octadecadienoic acid, 10-20 parts of carvone, 7-15 parts of essential oil and 0.1-2 parts of vitamin. The novel odorless and durable freshener has a durable and remarkable freshening effect, is free from bitterness and spiciness of mint, irritation and odor, and is resistant to high temperature; and very pleasant and very durable cooling and freshening effects can be achieved.

The invention discloses a burn tincture as well as a preparation method and application thereof. The burn tincture is prepared from lonicera confusa, fructus forsythiae, cape jasmine, polygonum cuspidatum, lithospermum, scutellaria baicalensis, borneol and menthol. The preparation method comprises the following steps of (1) mixing lonicera confusa, fructus forsythiae, cape jasmine, polygonum cuspidatum, lithospermum and scutellaria baicalensis, immersing the mixture in pure rapeseed oil, extracting and filtering; (2) cooling the filtrate, adding borneol and menthol into the filtrate for dissolving, and filtering; (3) subpackaging, sterilizing and removing fire toxin to prepare the burn tincture. The burn tincture has the effects of clearing heat, removing toxicity, astringing, promoting granulation, killing parasites to relieve itching and the like, and has an excellent effect for treating burns, eczema and bedsores.

The invention discloses a method for improving the safety of compound Maodongqing injection. According to the method, the pharmaceutical composition for injection is mainly prepared from extracts of holly holly, mountain silver flower, wind orchid and butyl p-hydroxybenzoate. The method of the present invention adopts the co-solvent with better safety and more obvious solubilizing effect to replace the co-solvent private plate 80 which has potential safety hazards and affects product quality in the compound Maodongqing injection, and the safety of butyl p-hydroxybenzoate is higher than that of the private plate. 80% and lower dosage, reducing the probability and risk of adverse drug reactions and improving the safety of clinical medication.

The invention discloses a toothpaste formula containing Desmodium, which comprises the following raw materials in parts by weight: 28-40 parts of mint, 8-15 parts of sea salt, 8-20 parts of reed root, 10-18 parts of orange peel, and 1-18 parts of Desmodium 10 parts, 1-9 parts of lobelia, 10-20 parts of sweet diced, 2-8 parts of kudzu flower, 10-20 parts of red peony, 15-30 parts of mountain silver flower, 20-30 parts of stevia, 1-salt 5 servings. The beneficial effects of the present invention are: the combination of the above raw materials produces a good synergistic effect, and the manufactured product has the health care effects of clearing away heat, fixing teeth, moisturizing, sterilizing, deodorizing, and refreshing breath, and is effective in preventing gum bleeding and gum swelling. Significant effect, while having a relieving effect on minor oral diseases.

The invention provides a single nucleotide polymorphism (SNP) site for identifying Lonicera japonica and Lonicera confusa. The SNPs comprises 219A / G and 864C / T. The invention also provides SNP (Single Nucleotide Polymorphism) loci capable of identifying Lonicera confusa subspecies, wherein the SNP loci comprise 40T / C, 97T / C, 107A / G, 141T / C, 219A / G, 235A / C, 252A / C, 327T / C, 364T / G, 543A / G, 597T / C, 616A / G, 630A / G, 711C / T, 797A / G, 807T / C, 846C / T, 849T / C and 864C / T. The invention also provides a primer for amplifying the SNP site. According to the method, the Lonicera japonica and Lonicera confusa are identified and analyzed by analyzing the SNPs of the FNSII, and the method can be used for identifying the Lonicera japonica and Lonicera confusa and identifying the Lonicera confusa subspecies.

The invention relates to traditional Chinese medicine composition for treating swine infectious atrophic rhinitis. The traditional Chinese medicine composition is prepared by components in parts by weight as follows: 15-35 parts of rheum officinale, 15-35 parts of herba cirsii japonici carbonisatum, 15-35 parts of subprostrate sophora, 15-35 parts of lonicera confusa, 15-45 parts of Chinese yam, 15-35 parts of hawthorn, 15-50 parts of liquorice, 15-45 parts of rhizome nardostachyos, 15-35 parts of herba pyrrosiae, 15-35 parts of salvia chinensis, 15-45 parts of concha haliotidis and 15-35 parts of rhizoma acori graminei. The traditional Chinese medicine composition has the benefits of reasonable formula, simplification of preparation, no toxic or side effects, no pollution, no medicine residues, no medicine resistance, superfine grinding, high bioavailability and obvious curative effect; and clinical tests prove that the composition has a specific effect in treating the swine infectious atrophic rhinitis.

The invention discloses a toothpaste formula containing loquat leaves, which comprises the following raw materials in parts by weight: 28-40 parts of calamus, 8-15 parts of sea salt, 8-20 parts of reed root, 10-18 parts of orange peel, and 1 part of loquat leaves ‑10 parts, 1‑9 parts of sorbitol, 10‑20 parts of tangerine, 2‑8 parts of kudzu flower, 10‑20 parts of jasmine, 15‑30 parts of mountain silver flower, 20‑30 parts of gallinaceae, Sichuan Shell 1‑5 servings. The beneficial effects of the present invention are: the combination of the above raw materials produces a good synergistic effect, and the manufactured product has the health care effects of clearing away heat, fixing teeth, moisturizing, sterilizing, deodorizing, and refreshing breath, and is effective in preventing gum bleeding and gum swelling. Significant effect, while having a relieving effect on minor oral diseases.

A rice spirit prepared from fructus chaenomelis produced in Xuancheng and lonicera confusa flower and a preparing method thereof are disclosed. The rice spirit is prepared from glutinous rice, the fructus chaenomelis produced in Xuancheng, the lonicera confusa flower, biond magnolia flower-bud, rose flower, Chinese angelica, fresh ginger, chrysanthemum flower, puffball, brown sugar, jiuqu and a sorghum spirit. The fructus chaenomelis produced in Xuancheng is soaked with extracting liquids of the fresh ginger, the puffball, the Chinese angelica, and the like, and therefore nutrition value of the fructus chaenomelis produced in Xuancheng can be exerted, and nutrition effects of the rice spirit are improved. The rice spirit is good in taste, rich in fragrance, sweet and sour, has effects of clearing away heat and toxins, relaxing the muscles and the joints, dredging collaterals, invigorating spleen, tonifying qi, moistening the intestines, relaxing bowel, tonifying blood, astringing yin, and the like, is free of side and toxic effects, is suitable for various crowds, and is a novel nutritive healthcare spirit.

The invention relates to the technical field of candies, in particular to functional type candies for clearing heat from throat and nourishing lungs and using polygonatum as a main material, and a preparation method of the functional type candies. The functional type candies are made from the following raw materials in parts by weight of 30-450 parts of the polygonatum, 30-450 parts of lonicera confusa dc, 30-450 parts of lilies, 30-450 parts of licorice roots, 450-800 parts of granulated sugar, 100-400 parts of glucose, 50-300 parts of maltodextrin, 10-100 parts of vitamin C, 10-100 parts ofcitric acid and 0.5-20 parts of menthol. Through the adoption of the functional type candies disclosed by the invention, the sugar content of the candies is reduced, and the hardness, the adhesion property, the elasticity and the cohesiveness of the candies are also effectively improved.

The invention relates to wild honeysuckle flower extract, which mainly comprises the following compositions: macranthoside A,II b, macranthoside B,IIIb, 3-O-alpha-L-pyran rhamnose (1-2)-alpha-L-pyran arabinose-hederagenin and 3-O-beta-D-glucopyranose (1-4)-beta-D-glucopyranose (1-3)-alpha-L-pyran rhamnose (1-2)-alpha-L-pyran arabinose -oleanolic acid. The invention also relates to a method for preparing the compound and application of the compound in the aspect of cancer.

The invention discloses an ecological planting method of Lonicera confusa in the field of Lonicera confusa planting. The method comprises steps as follows: (1) land selection and preparation; (2) seedling planting; (3) topdressing; (4) pruning; (5) disease and pest prevention and control: a, composted organic fertilizer with the mass fraction ratio of nitrogen to phosphorus to potassium being 13:9:10 is adopted; b, insect-plague branches, dead branches, dense branches and weak branches are pruned; c, purified water is sprayed to front surfaces of leaves firstly, then 75% industrial alcohol is atomized and sprayed on back surfaces of the plant leaves, and natural enemies are introduced; d, the insect-plague branches, the dead branches, residues and fallen leaves are burnt in a centralized manner, and disease points are sterilized and filled with pollution-free soil; (6) picking. With the adoption of the scheme, biological prevention and control replace chemical prevention and control, conditions that medicines inside the Lonicera confusa and heavy metal content of the Lonicera confusa exceed the standard are directly reduced, pollution to soil, water sources and the like is avoided, the environment inside a planting area is optimized, and a basic guarantee is provided for excellent quality of the Lonicera confusa.

The invention belongs to the field of Chinese medicine pharmacy, and discloses a mailuoning composition. The composition is prepared from the following raw material drugs in parts by weight: 1 to 4 parts of honeysuckle and lonicera confusa, 1 to 4 parts of dendrobe, 1 to 4 parts of twotooth achyranthes root, and 1 to 4 parts of figwort root, wherein on the basis of 100 percent of the weight sum of the honeysuckle and the lonicera confusa, the ratio of the honeysuckle to the lonicera confusa is between 20 percent and 50 percent:50 percent. According to the specification of drugs in the Chinese Pharmacopoeia 2005 edition, the honeysuckle and the lonicera confusa are itemized, and the proportion between the two drugs are studied by adopting a plurality of pharmacological experiments, and an optimized proportion between the two drugs is selected.

The invention discloses an external preparation for treating varicose veins. The invention has a certain curative effect on local pain, nodule, acid deposition and numbness caused by vasculitis and varicose veins. It has the effect of promoting blood circulation, reducing swelling and relieving pain.

The invention relates to a detection method for obtaining material composition and total antioxidant activity of lonicera confusa. The detection method comprises the following steps: preparing a test solution; preparing a DPPH solution; preparing a series of concentration gradient VC solution as a standard substance, carrying out HPLC-DPPH analysis by taking DPPH as a to-be-scavenged object, and establishing a regression equation of relationship between VC concentration and free radical scavenging rate; and injecting the test solution into the HPLC-DPPH analysis system to obtaining the chemical ingredient information of a sample and the total free radical scavenging rate of the sample, and substituting into the regression equation, so that the total antioxidant activity of the sample is obtained. The detection method provided by the invention has the advantages that an HPLC-DPPH online combination method is adopted, and chemical fingerprint chromatography information and the total antioxidant activity of the lonicera confusa can be obtained at the same time, so that the advantage of carrying out quality control and 'spectrum-effect' evaluation on the lonicera confusa is realized.

The invention discloses a toothpaste formula containing jasmine, which comprises the following raw materials in parts by weight: 28-40 parts of mint, 8-15 parts of sea salt, 8-20 parts of reed root, 10-18 parts of orange peel, and 1-18 parts of Daqingye 10 parts, 1-9 parts of sorbitol, 10-20 parts of tangerine, 2-8 parts of kudzu flower, 10-20 parts of jasmine, 15-30 parts of mountain silver flower, 20-30 parts of stevia, 1-salt 5 servings. The beneficial effects of the present invention are: the combination of the above raw materials produces a good synergistic effect, and the manufactured product has the health-care effects of clearing away heat, fixing teeth, moisturizing, sterilizing, deodorizing, and refreshing breath, and is effective in preventing gum bleeding and gum swelling. Significant effect, while having a relieving effect on minor oral diseases.