1543results about How to "Good curative effect" patented technology

The invention provides a cerebral hemorrhage personalized treatment scheme optimization method and system based on big data analysis, and relates to the technical field of data analysis, and the method comprises the steps: constructing a cerebral hemorrhage patient multi-source heterogeneous clinical database, extracting feature subsets, carrying out semantic alignment, carrying out time sequence modeling and fusion, and obtaining a patient panoramic feature representation; constructing a cerebral hemorrhage diagnosis and treatment knowledge graph, adding the cerebral hemorrhage diagnosis and treatment knowledge graph to a preset graph attention network, distributing weights, obtaining knowledge-enhanced patient feature representation and taking the knowledge-enhanced patient feature representation as a state, generating an action space based on an optional treatment scheme, constructing a reward function and determining a candidate treatment scheme; performing medication suitability analysis, performing semantic conflict identification in combination with the patient allergy history and complication, and performing screening to obtain a suitable candidate treatment scheme set; and for each scheme, predicting a multi-dimensional prognosis index, constructing a multi-criterion decision matrix, combining personal influence factors, adjusting the weight of each index, modeling an optimization problem and determining an optimal treatment scheme.

The invention relates to a closed-loop multi-guide multi-mode time domain interference electrical stimulation system and method. The method comprises the steps that a software part determines stimulation parameters; the automatic electrode position adjusting device adjusts the spatial position of the multi-conductive-electrode device, and the multi-conductive-electrode device stimulates the position of a target spot; the current output precision and impedance monitoring module monitors the precision and impedance information of electrode output current, and the core main control and functional circuit module adjusts a control signal according to the precision and impedance information; when the multi-conducting-electrode device conducts stimulation, the electroencephalogram device synchronously collects electroencephalogram signals and uploads the electroencephalogram signals to the electroencephalogram analysis algorithm module of the software part, the electroencephalogram analysis algorithm module evaluates and feeds back the effectiveness and the effect of stimulation, and the time domain interference electrical stimulation function module and the target area dynamic adjustment algorithm module optimize stimulation parameters according to the effectiveness and the effect of stimulation. Through the arrangement, a real-time closed-loop feedback control system is formed, continuous monitoring, real-time optimization and adjustment of electrical stimulation parameters and dynamic adjustment of a stimulated brain target region are realized, and the accuracy and safety of current output are ensured.

The invention provides a correlation analysis method for a lung CT image, and the method comprises the steps: obtaining a lung multi-modal image which comprises a computed tomography image and a positron emission tomography image, and carrying out the denoising, enhancement and standardization preprocessing of an original image according to the imaging principles and image characteristics of different modals; extracting a lung lesion region of interest from the registered multi-modal image, sketching and segmenting the lesion, and quantitatively analyzing the volume and shape geometric morphological characteristics of the lesion; based on a curative effect result, correlation between radiomics features and patient prognosis is analyzed, recurrence and metastasis risks and lifetime under different feature expressions are estimated, a curative effect prediction model is constructed in combination with image features and clinical indexes, and long-term individualized evaluation is performed on patient prognosis.

The invention relates to a nano antibody targeting cadherin 17 and application thereof, and relates to the technical field of immunology and molecular biology, the amino acid sequence of a complementary determining region of the nano antibody targeting cadherin 17 comprises CDR1 shown as any one of SEQ ID NO: 21-32, CDR2 shown as any one of SEQ ID NO: 34-45, and CDR3 shown as any one of SEQ ID NO: 47-58. According to the invention, an alpaca immune phage display library is constructed, a series of nano antibody molecules targeting cadherin 17 (CDH17) are screened from the alpaca immune phage display library, and functions and applications of the nano antibody are verified at various levels of CDH17 antigen protein, CDH17 target cells, CDH17 CAR-T cells and the like.

The invention provides a chronic disease co-patient accurate medication real-time management system based on an AI large model, and the system comprises accurate medication guided by the AI large model, through the mathematical modeling and simulation technology, the related information of patients, medicines and diseases is integrated, and accurate medication is guided. According to the method, the administration scheme can be formulated more accurately, the curative effect is improved, side effects are reduced, a patient medication report is provided for physicians and pharmacists, the physicians and pharmacists can dynamically master patient medication information in real time, reference is provided for the physicians to formulate the next medication scheme, and the treatment effect on chronic disease patients is improved.

The invention relates to application of fecal microbe transplantation (FMT) in depressive disorder treatment, in particular to application of a fecal microbe transplantation (FMT) composition based on a human intestinal tract fecal microbe composition in depressive disorder treatment. The invention also relates to application of the pharmaceutical composition or the medicine box in preparation of a medicine for treating depressive disorder, and the pharmaceutical composition or the medicine box contains a therapeutically effective amount of the human intestinal tract coprophilous fungus composition.

The invention relates to a humanized nano antibody targeting cadherin 17 and application of the humanized nano antibody, and relates to the technical field of immunology and molecular biology. The complementarity determining region of the humanized nano antibody comprises a CDR1 of which the amino acid sequence is shown as SEQ ID NO: 2, a CDR2 of which the amino acid sequence is shown as SEQ ID NO: 4 and a CDR3 of which the amino acid sequence is shown as SEQ ID NO: 6; a framework region of the humanized nano antibody comprises an FR1 of which the amino acid sequence is shown as any one of SEQ ID NO: 1 and SEQ ID NO: 8, an FR2 of which the amino acid sequence is shown as any one of SEQ ID NO: 3, SEQ ID NO: 9 and SEQ ID NO: 11, an FR3 of which the amino acid sequence is shown as any one of SEQ ID NO: 5 and SEQ ID NO: 10, and an FR4 of which the amino acid sequence is shown as SEQ ID NO: 7. According to the humanized nano-antibody, the immunogenicity of the nano-antibody is reduced, the targeted binding activity and killing activity are improved, and the humanized nano-antibody can be used for developing immunodetection reagents, CAR-T / NK cell drugs and antibody drugs.

The invention provides an automatic determination method and system for an individualized medication adjustment dosage, and the method comprises the steps: calculating an initial administration scheme through employing a weighting result of a first atrioventricular model and a second atrioventricular model based on the physiological data and medication types of a patient; meanwhile, when the initial administration scheme of the patient is poor in effect or has adverse reaction, the administration scheme of the patient is adjusted. Compared with the prior art, the method has the advantages that the medication dosage can be accurately predicted and adjusted, adjustment suggestions can be given in real time through a feedback mechanism, and the safety and the curative effect of individualized medication are ensured.

The invention discloses an acupuncture robot system in the field of acupuncture equipment, and the system comprises an acupoint recognition module which is used for collecting body surface image information and sign data of a patient, and obtaining acupoint position information through a pre-trained deep learning model; the mechanical arm control module is used for controlling the mechanical arm to perform acupuncture operation according to the acupoint position information and collecting force feedback information in real time; the monitoring feedback module comprises a physiological monitoring unit and a real-time feedback unit, and the physiological monitoring unit is used for monitoring the physiological reaction of the patient and obtaining physiological information; the real-time feedback unit is used for collecting and processing the acupoint position information, the force feedback information and the physiological information so as to adjust the acupuncture strength and angle in real time. According to the acupuncture robot system, the image recognition and sensor fusion technology is introduced, the accuracy of acupoint positioning is improved, physiological data of a patient can be collected in real time, the acupuncture applying force and depth are adjusted according to the physiological data, and the treatment effect is further improved.

The invention relates to the field of biomedical materials, discloses a hydrogen sulfide / nitric oxide synergistic anti-inflammatory and anti-coagulation repair promoting coating as well as a preparation method and application thereof, and provides a coating with anti-inflammatory, anti-coagulation and tissue repair promoting functions through the synergistic effect of hydrogen sulfide and nitric oxide. The coating comprises a hydrogen sulfide donor which can spontaneously release hydrogen sulfide or a precursor thereof or release hydrogen sulfide under external stimulation; the coating further comprises a component capable of catalyzing the release of nitric oxide from the endogenous nitric oxide donor. The coating is covalently connected with the surface of a base material through a chemical means to form firm interface bonding; and the coating has a multi-cross-linked network structure, so that the coating is endowed with good stability, and long-term functional application of the coating on the surface of a biomedical material is ensured. The method can be widely applied to surface modification of biomedical materials, especially coating functionalization of implanted instruments such as valve clips, intravascular stents, heart valves, occluders, vascular grafts and myocardial patches.

The invention provides a composition with a blood sugar reducing function and application thereof, and belongs to the technical field of diabetes treatment. The composition is prepared from burdock root extract, folium ilicis purpurea extract, hypoglycemic decapeptide, trehalose, sodium benzoate, glycerol, vitamin C and water. The composition disclosed by the invention has a multi-target synergistic effect, and by integrating natural plant extracts and functional peptides, multiple targets related to diabetes mellitus are adjusted, so that the blood sugar level is remarkably reduced, and cholesterol metabolism, oxidative damage and inflammatory response are effectively improved. The composition can be used for treating type 2 diabetes mellitus and has a good clinical application prospect.

The invention discloses a leak-free core-shell hydrogel microsphere delivery system for non-contact flora transplantation as well as a construction method and application of the leak-free core-shell hydrogel microsphere delivery system. According to the invention, bacteria are encapsulated in a core of a core-shell microsphere through a two-step photo-initiation emulsion polymerization method of methacrylic acid gelatin, and a non-contact microbiota transplantation system (NMTS) is constructed. The NMTS can be used for biological encapsulation of various strains, shows encapsulation efficiency close to 100%, and has little influence on bacterial activity at the same time. NMTS demonstrates: a shielding effect that protects sealed bacteria from low pH values in the gastrointestinal tract and bile acid disruption; sufficient mechanical strength ensures that bacterial leakage is prevented and the infection risk is eliminated in the whole gastrointestinal tract delivery process; and internal and external substance exchange is realized, and the intestinal microorganism structure is remodeled. The invention provides a unique bacterial cell microencapsulation method which is a non-contact, safe and effective micropopulation transplantation method.

The invention relates to the technical field of atherosclerosis related drugs, in particular to a macrophage membrane functionalized manganese dioxide nano-drug as well as a preparation method and application thereof in treatment of atherosclerosis. The invention relates to a macrophage membrane functionalized manganese dioxide nano-drug, which comprises an HMnO2 carrier, colchicine is loaded on the HMnO2 carrier, and a macrophage membrane is coated outside the HMnO2 carrier. The preparation can be applied to practical operation of preparing medicines for treating atherosclerosis. According to the technical scheme, the technical problem of limited treatment effect caused by single action mechanism of medicines for treating atherosclerosis in the prior art can be solved. The nano-drug in the scheme can remove ROS to play an anti-inflammatory effect, reprogram macrophages and promote cholesterol excretion, and is used for synergistically treating atherosclerosis. The macrophage membrane can target an inflammation part and escape from an immune system. And the side effect of the nano-drug is relatively small, so that the nano-drug has ideal popularization and application prospects.

The invention belongs to the technical field of veterinary preparations, and particularly relates to a tilmicosin premix and a preparation method thereof. The tilmicosin premix is prepared from the following raw materials: tilmicosin, a polylactic acid-glycolic acid copolymer, lecithin, modified hydroxypropyl methyl cellulose, grafted polyvinylpyrrolidone, polyethylene glycol and an antioxidant, a solid dispersion is formed through lecithin and grafted polyvinylpyrrolidone, the solubility and stability of tilmicosin are enhanced, polylactic acid-glycolic acid copolymer nano-microspheres are prepared through a double-emulsion solvent evaporation method, slow release of drugs is achieved, dodecyl modified hydroxypropyl methyl cellulose and polyethylene glycol are combined, and the sustained release effect is achieved. The solubility and the slow release characteristic are further enhanced. The activity of the granular premix is effectively preserved, and the granular premix is convenient to use and transport.

The invention discloses an application of isorhamnetin-3-O-neohesperidin in preparation of a medicine for preventing and / or treating benign prostatic hyperplasia. In-vitro experiments show that the isorhamnetin-3-O-neohesperidin can inhibit proliferation of prostatic hyperplasia cells, promote apoptosis of the prostatic hyperplasia cells and regulate inflammatory response of the prostatic hyperplasia cells, and rat experiments show that the isorhamnetin-3-O-neohesperidin can improve the hormone endocrine disorder condition of an animal model body, and can inhibit the prostatic hyperplasia cells and promote the prostatic hyperplasia cell apoptosis and regulate the inflammatory response of the prostatic hyperplasia cells. The anti-inflammatory ability of an animal model is enhanced, and the traditional Chinese medicine composition has a relatively good treatment effect on prostatic hyperplasia caused by testosterone propionate. The medicine for preventing and / or treating benign prostatic hyperplasia, provided by the invention, contains a pharmacodynamic dose of isorhamnetin-3-O-neohesperidin and a pharmaceutically acceptable carrier or auxiliary material, can be prepared into a medicine dosage form which is convenient for clinical use and can play an optimal curative effect, and has a relatively high clinical application value.

The invention discloses a PARP1 / CDK6 double-target inhibitor as well as a preparation method and application thereof, the PARP1 / CDK6 double-target inhibitor is selected from a compound with a structure as shown in a formula I or pharmaceutically acceptable salt or solvate thereof, L is selected from # imgabs0 #, and R is selected from hydrogen, deuterium, halogen, hydroxyl, sulfydryl, cyano, nitro, methoxyl, C1-C8 alkyl or C3-C8 cycloalkyl. The PARP1 / CDK6 double-target inhibitor disclosed by the invention has a relatively good effect on human breast cancer cells, and keeps good in-vitro enzyme inhibition activity on CDK6 and PARP1. The invention discloses an application of a CDK6 / BRD4 double-target inhibitor in preparation of a medicine for treating PARP1 / CDK6 mediated diseases. The invention discloses an application of a PARP1 / CDK6 double-target inhibitor in preparation of a medicine for treating or preventing triple negative breast cancer. # imgabs1 #

The invention belongs to the technical field of medicines, and particularly discloses application of moss phenol glucoside in preparation of medicines for preventing and / or treating tumors. According to the method, activated CD8 + T cells, MC38-OVA cells and traditional Chinese medicine monomeric compounds are co-cultured, the traditional Chinese medicine monomeric compounds capable of effectively promoting the anti-tumor activity of the CD8 + T cells are selected by utilizing a high-content screening technology, and finally, the experiment is carried out by taking the moss phenol glucoside as a research object. In-vitro experiment results show that the moss phenol glucoside can significantly promote T cell activation, promote release of cell factors such as IFN-gamma and TNF-alpha, and enhance the killing effect of T cells on tumors. A mouse in-vivo tumor-bearing experiment result shows that the moss phenol glucoside can promote the anti-tumor activity of T cells so as to inhibit tumor growth, has no obvious toxic or side effect, can be used for preparing the medicine for preventing and / or treating tumors, and has a potential clinical application prospect and a relatively high economic value.

The invention provides a drug-loaded callicarpa nudiflora-derived extracellular vesicle as well as a preparation method and application thereof, and relates to the technical field of pharmaceutical preparations. The drug-loaded callicarpa nudiflora-derived extracellular vesicle has relatively high encapsulation efficiency and drug loading rate and good gastrointestinal tract stability and biocompatibility, can target a colitis disease part to reduce adverse reaction of a drug and improve the curative effect, solves the problem that the drug is insoluble in water, and can be used for preparing the drug-loaded callicarpa nudiflora-derived extracellular vesicle. The invention provides a novel drug delivery strategy for treating the ulcerative colitis, and is expected to become an effective strategy for clinically treating the ulcerative colitis, thereby achieving the effects of synergistically treating the ulcerative colitis and improving the effectiveness and safety of drug delivery.

The invention discloses a three-section self-assembly composite polypeptide nanoparticle for targeted repair of endothelial barrier and regulation and control of immune recruitment cascade and a preparation method and application thereof, and the preparation method comprises the following steps: (1) preparation of a hydrophilic section head multifunctional peptide solution, (2) preparation of a middle section connector ROS response thioketal solution, and (3) preparation of a three-section self-assembly composite polypeptide nanoparticle for targeted repair of endothelial barrier and regulation and control of immune recruitment cascade. (5) preparing a three-section type compound of a hydrophilic section, the hydrophobic section and the middle section, and (6) mixing the connection compound solutions of the three types of polypeptide of the hydrophobic section, the middle section and the hydrophilic section, and dialyzing to remove DMSO (Dimethylsulfoxide), so that the compound solution is changed from an organic phase to a water phase, and the three-section type compound of the hydrophobic section, the middle section and the hydrophilic section is obtained. And promoting amphiphilic self-assembly of the compound and co-assembly of the three polypeptide compounds, and freeze-drying to obtain the three-section type self-assembly composite polypeptide nanoparticles. According to the invention, inflammatory endothelial cells are targeted, local high ROS microenvironment is responded, endothelial barrier repair peptide is released to repair endothelial barrier, complement receptor antagonistic peptide is released to regulate complement cascade reaction so as to recover immune microenvironment, and body inflammation and immune disorder are cooperatively regulated.

The invention belongs to the field of biological medicines, and particularly relates to an optimized antigen peptide aiming at L858R point mutation of an EGFR exon 21 region and application of the optimized antigen peptide. Compared with a mutant peptide, the optimized antigen peptide has stronger immune cross reaction, can improve the immunoreactivity or curative effect of related tumor vaccines, and can effectively cover more patient crowds.

The invention discloses an artificial antigen presenting cell for efficiently preparing a chimeric antigen receptor T cell (CAR-T) and a construction method of the artificial antigen presenting cell, and belongs to the field of cell therapy and immunotherapy, the artificial antigen presenting cell takes a K562 cell as a platform, an anti-CD3 single-chain antibody, an anti-CD28 single-chain antibody, a membrane binding type cell factor and a costimulatory ligand are stably expressed through genetic engineering, and the chimeric antigen receptor T cell (CAR-T) is obtained. And the local concentration of the anti-CD3 antibody is improved by adopting an HOTag3 tool. The multi-signal integration strategy obviously enhances the activation and proliferation capacity of the T cells, promotes the CAR-T cells to maintain a low differentiation state, and endows the CAR-T cells with excellent anti-tumor activity and durability. The artificial antigen presenting cell provides a novel efficient tool for the field of cellular immunotherapy, and is expected to promote development of more efficient and safer CAR-T therapy to cope with challenges of various malignant tumors.

The invention provides mupirocin ointment as well as a preparation method and an application method thereof. The weight of mupirocin accounts for 0.1-0.5% of the total weight of the ointment. The water-soluble matrix is selected from polyethylene glycol, glycerol, propylene glycol or a mixture thereof. The stability and the curative effect of the medicine can be improved, and meanwhile, the safety and the use convenience of the ointment are ensured.

The invention relates to the field of health-care tea, in particular to agastache rugosus tea for comprising the following raw materials in parts by weight: 8 parts of agastache rugosus, 8 parts of poria cocos, 10 parts of orange peel, 2 parts of elsholtzia, 8 parts of platycodon grandiflorum, 3 parts of myristica fragrans, 20 parts of clove, 8 parts of radix angelicae, 5 parts of raisin tree seed, 5 parts of white hyacinth bean, 8 parts of hawthorn, 7 parts of purslane, 8 parts of fructus amomi, 10 parts of fennel, 10 parts of pawpaw, 6 parts of mulberry leaf, 6 parts of malt, 8 parts of honeysuckle, 5 parts of purple perilla, 5 parts of liquorice, 3 parts of lotus leaf, 9 parts of purple perilla seed, 8 parts of cinnamon, 8 parts of dried ginger, 8 parts of houttuynia cordata, 8 parts of sweet basil and 8 parts of mesona chinensis. The agastache rugosus summer-heat tea solves the technical problem that existing agastache rugosus summer-heat tea and other medicinal tea drinks cannot be used as daily health tea drinks, meanwhile, the invention provides a development method of the agastache rugosus summer-heat tea, and it is guaranteed that the efficacy of a finished product is reserved to the maximum extent.

The invention discloses a boron manganese tannate nanoparticle as well as a synthesis method and application thereof. The synthesis method of the tannic acid boron manganese nanoparticles comprises the following steps: sequentially dropwise adding a bivalent manganese salt solution, a boric acid solution, a polyethylene glycol solution and a bovine serum albumin solution into pure water under water bath ultrasonic or magnetic stirring to obtain an assembly stock solution, and adding a tannic acid solution into the assembly stock solution to initiate assembly; and continuously carrying out water-bath ultrasonic treatment or magnetic stirring for a period of time, and then carrying out ultrafiltration to remove free drug molecules, so as to obtain the boron manganese tannate nanoparticles capable of mediating boron neutron capture therapy and magnetic resonance imaging. The boron manganese tannate nanoparticles can improve the boron intake in tumors and prolong the retention time of boron atoms in the tumors in boron neutron capture therapy, drug distribution is monitored through the nuclear magnetic resonance imaging technology, then the treatment effect of the boron neutron capture therapy is improved, the preparation method is simple, the stability is good, the size is uniform, the boron loading amount is high, and the application prospect is wide. The biological safety is good, and the repeatability is high.

The invention relates to dithiolane modified beta-cyclodextrin, a preparation method thereof and application of the dithiolane modified beta-cyclodextrin as a drug carrier. The method comprises the following steps: carrying out acylation reaction on beta-cyclodextrin and lipoic acid, and modifying different numbers of dithiolane on the beta-cyclodextrin by changing a feeding ratio; the beta-cyclodextrin has a plurality of hydroxyl groups, and the activity of the hydroxyl groups at the C6 position is relatively high. The hydrophobic cavity of the dithiolane-modified beta-cyclodextrin can be loaded with a hydrophobic small-molecule drug, and the hydrophobic small-molecule drug can be loaded into the dithiolane-modified beta-cyclodextrin under the condition of heating reflux to form a nano-drug. The disulfide bond on the surface of the nano-drug and sulfydryl on protein or lipid on the outer side of a cell membrane are subjected to dynamic covalent thiol exchange, so that the nano-drug enters cells through a thiol-mediated cellular uptake way, endosomes and lysosomes can be avoided, the drug is quickly and directly delivered to the cytoplasm, degradation of the drug in the lysosomes is reduced, and the drug delivery efficiency is improved. The utilization rate of small-molecule drugs is improved, side effects are reduced, and better curative effects are achieved.

The invention discloses an application of naringenin nanoparticles in preparation of a ceftiofur long-acting preparation. The invention discloses naringenin (5, 7-dihydroxy-2 (4-hydroxyphenyl) chroman-4-ketone), which is a flavonoid substance. The naringenin nanoparticles are prepared, the naringenin nanoparticles are mixed with the ceftiofur for combined use, and it is found that the naringenin can effectively intervene in the pharmacokinetic process of the ceftiofur and significantly prolong the in-vivo half-life period of the ceftiofur, so that the in-vivo action time of the ceftiofur is prolonged, and the curative effect of the ceftiofur is improved. Moreover, the application method is simple, easy to operate, low in cost and suitable for large-scale popularization.

The invention relates to the technical field of medicine detection, and discloses medicine raw material detection equipment for improving the purity of raw materials, the medicine raw material detection equipment comprises a base and a supporting box, the bottom of the supporting box is fixedly connected to the outer side of the base, the top of the base is fixedly connected with a detection mechanism, and the top of the detection mechanism is fixedly connected with a detection plate; the top end of the supporting box is fixedly connected with a driving box, multiple filtering and impurity removing can be conducted on medicine raw materials through the impurity removing assembly, impurities in the raw materials can be screened out while the caked raw materials are screened out, the purity of the medicine raw materials is improved, the content of invalid or harmful ingredients in medicine can be reduced by removing the impurities, and therefore the medicine raw materials can be conveniently taken out. The purity and quality of the medicine are improved, the raw materials with higher purity can be used for preparing the medicine which is more efficient, safer and more stable, the treatment effect and the satisfaction degree of a patient are improved, and the content of active ingredients of the medicine can be improved by removing impurities, so that the curative effect of the medicine is enhanced.

The invention relates to the technical field of cell activity detection, in particular to an umbilical cord blood stem cell activity detection method and system.The method comprises the following steps that cells are separated from a fresh umbilical cord blood sample in a sterile environment, cell activity preliminary identification is conducted on the separated stem cells, and a cell activity evaluation result is generated; screening cells with activity meeting a preset standard, and performing function evaluation to obtain a screened cell set. According to the method, through accurate preliminary cell viability identification and function evaluation, the scheme optimizes the selection standard of umbilical cord blood stem cells, effectively screens out cells with high regeneration capacity and biological activity, enhances the success rate of cell therapy and reduces the risk caused by improper selection, and by analyzing the gene regulatory network of the screened cells, the cell therapy effect is improved. The functionality is accurately evaluated, it is ensured that only the most potential cells are used for subsequent culture and clinical application, the curative effect and the product quality are remarkably improved, and the culture efficiency and the success rate are further improved through an optimized culture scheme and a monitoring system.

The invention relates to the field of biological medicine, in particular to application of cepharanthine in preparation of a pathogenic bacterium biofilm scavenger, an anti-pathogenic bacterium medicine and a medical equipment coating material. Staphylococcus aureus is taken as a pathogenic bacterium, the removal effect of cepharanthine on a biological membrane is detected through biological membrane formation and destruction experiments, and the curative effect of cepharanthine on infection is evaluated by constructing a staphylococcus aureus infected mouse model. The result shows that the cepharanthine inhibits the formation of the staphylococcus aureus biological membrane and destroys the formed biological membrane; animal experiments show that the cepharanthine improves the survival rate of mice infected with the staphylococcus aureus, reduces the colonial colonization number of lungs of the infected mice, and improves the elimination capability of a host to pathogenic bacteria. Therefore, the invention has important significance in the aspects of research and development of targeted biological membranes and drugs for resisting drug-resistant bacterium infection, improvement of the curative effect of antibiotics, prolonging of the service life of the drugs and the like.

The invention discloses a traditional Chinese medicine plant combination anti-hair loss and hair growth formula optimization method based on a neural network algorithm, and the method comprises the following steps: S1, collecting hair health data of a user, and building a personalized health file; s2, based on the health record, analyzing the physiological and psychological states of the user in real time, and establishing an emotion-hair growth feedback mechanism to evaluate the risk of alopecia; s3, analyzing the health archive by using a deep neural network, predicting an alopecia trend and generating a personalized alopecia prevention and hair growth scheme; s4, matching optimal plant components and proportions through a neural network optimization model, and dynamically adjusting a pharmacodynamic model; s5, adaptively adjusting the plant formula proportion through a quantum neural adaptability learning mechanism; s6, simulating different formula effects through the virtual test platform, optimizing the formula and feeding back to the health file; and S7, forming a closed-loop feedback mechanism through continuous user feedback and physiological monitoring results, and regularly optimizing the formula. Through personalized analysis and dynamic adjustment, an accurate anti-hair loss and hair growth solution is provided.