25 results about "Bupleurum" patented technology

This invention belongs to the field of traditional Chinese medicine technology, and particularly relates to a traditional Chinese medicine composition and its application for the prevention and / or treatment of rheumatoid arthritis. The composition comprises the following medicinal materials: dried aconite root slices, dried ginger, astragalus root, codonopsis root, stir-fried atractylodes rhizome, poria cocos, cinnamon twig, white peony root, bupleurum root, angelica root, dioscorea rhizome, vinegar-processed myrrh, stir-fried peach kernel, honeysuckle flower, sea bream vine, and asarum root. The traditional Chinese medicine composition of this invention has good efficacy in treating rheumatoid arthritis, as well as rheumatoid arthritis accompanied by anxiety and depression. Its formula is reasonable, has no toxic side effects, and its efficacy is safe and reliable.

The application discloses a kind of oil-containing water body separation membrane for refining process of Bupleurum volatile oil and preparation method and application.The preparation method of the application is first mixed and dissolved according to proportion with cellulose acetate and cellulose nitrate powder, form casting membrane liquid, and the base membrane is prepared using non-solvent phase conversion method;Second, the film is deacetylated;After that, it is soaked in acyl chloride n-hexane solution for crosslinking;Finally, by in-situ hydrolysis of silane coupling agent on the membrane surface, a hydrophobic surface is prepared, and an oil-containing water body separation membrane for refining process of Bupleurum volatile oil is obtained.This method forms a hydrophobic layer on the surface of the membrane, which strengthens the rapid passage of Bupleurum volatile oil molecules and inhibits the penetration of water;Using the oil-containing water body separation membrane avoids the formation of emulsion during oil-water separation, showing high separation efficiency and stability, and widening the application of cellulose acetate membrane in traditional Chinese medicine preparation process.

The present application belongs to the technical field of aquaculture, and particularly relates to a plant source composite preparation for reducing antibiotic residues in cultured aquatic products, and a preparation method and use method thereof. The plant source composite preparation comprises the following raw materials in parts by weight: 20.0-35.0 parts of a composite plant extract, 0.5-2.0 parts of glucose oxidase, and 0.8-3.0 parts of bile acid; wherein the composite plant extract comprises extract of dried orange peel, extract of licorice, extract of sea buckthorn, extract of sophora fruit, extract of mulberry leaf, extract of bupleurum, and extract of green tea. The plant source composite preparation is prepared by stepwise mixing, and then mixed with feed at a ratio of 0.4-1:100 and fed for 5-10 days, so as to accelerate the metabolism and excretion of antibiotics, shorten the drug holiday, and ensure the quality and safety of aquatic products.

The present application relates to a kind of traditional Chinese medicine technical field, especially to a kind of antiviral traditional Chinese medicine composition, antiviral traditional Chinese medicine formula granule and its preparation method and application.The antiviral traditional Chinese medicine composition includes the following weight parts of component: 8 parts to 18 parts of Magnolia officinalis, 10 parts to 20 parts of Trichosanthes, 5 parts to 15 parts of Scutellaria, 5 parts to 15 parts of Bupleurum, 2 parts to 10 parts of Atractylodes, 2 parts to 10 parts of Ginger, 2 parts to 10 parts of North Adenophora, 3 parts to 11 parts of Red Shaoyao.The antiviral traditional Chinese medicine composition of the present application has good antiviral effect.

The present application relates to the technical field of oral liquid, in particular to a kind of oral liquid for preventing and treating perinatal energy metabolism disorder disease of dairy cow and preparation method thereof, it is characterized in that, the oral liquid for preventing and treating perinatal energy metabolism disorder disease of dairy cow is made of the following components, by weight parts: artemisia capillaris 200~300 parts, gardenia 150~200 parts, bupleurum 100~150 parts, polygonatum 50~100 parts, radix paeoniae alba 50~100 parts, liquorice 10~50 parts, nicotinic acid 1~10 parts, propylene glycol 200~300 parts, fructose diphosphate sodium 1~10 parts, pure water 200~400 parts.The oral liquid for preventing and treating perinatal energy metabolism disorder disease of dairy cow can prevent and treat ketosis, fatty liver and liver damage at the same time, comprehensively improve the constitution of new cow, improve immunity, improve physical indicators and reproductive performance, increase economic benefits.

This invention discloses an auxiliary device for thin-layer chromatography identification of Bupleurum chinense leaves, relating to the field of traditional Chinese medicine detection technology. It includes a single-slot developing assembly, with a base assembly fixedly mounted at the bottom and a developing solvent containing mechanism nested at the top. A mixing drive mechanism is jointly provided on the top and inside of the developing solvent containing mechanism, and a dual triggering mechanism is provided on the outside of the mixing drive mechanism. This invention reduces the difficulty of preparing the developing solvent for Bupleurum chinense leaf thin-layer chromatography identification, eliminates the need for manual input of the developing solvent, and allows the silica gel thin-layer plate to complete pre-saturation during suspension. Therefore, it eliminates the need for separate slots for placing the developing solvent and silica gel thin-layer plate, saving manpower, reducing the operational difficulty of Bupleurum chinense leaf thin-layer chromatography identification, and improving the efficiency of Bupleurum chinense leaf thin-layer chromatography identification.

This invention provides a traditional Chinese medicine composition for treating anxiety, depression, and / or sleep disorders, its preparation method, and its application, belonging to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition includes the following raw materials: *Aconitum carmichaelii* root slices, calcined magnetite, stir-fried jujube seed, prepared polygala tenuifolia root, prepared pinellia tuber, tangerine peel, stir-fried immature bitter orange, ginger-processed bamboo shavings, albizia bark, poria cocos, coix seed, bamboo leaf bupleurum root, oyster shell, licorice root, and dragon bone. The preparation method includes: first decocting the *Aconitum carmichaelii* root slices, then adding the remaining medicinal ingredients and decocting with water; concentrating the filtrate into a clear paste, adding excipients, and compressing into tablets. Animal experiments show that, compared with the model group, the traditional Chinese medicine composition of this invention can significantly increase the number of times mice enter the central region and the dwell time in the open field test, and improve the number of times mice enter the open arms of the elevated cruciate maze and the dwell time; hippocampal Nielsen staining shows that neurons are neatly arranged and cell density is well restored. This invention has the effects of warming the kidney and suppressing yang, resolving phlegm and calming the mind, and can be used to prepare drugs for treating anxiety, depression, and / or sleep disorders.

The present application relates to the technical field of bupleurum tissue culture, and discloses a bupleurum tissue culture device and culture method, which comprises an exhaust main mechanism, a cabinet door mechanism is movably installed on the surface of the exhaust main mechanism, a pump liquid mechanism is installed in the cabinet door mechanism, constant temperature heating mechanisms are installed inside the two sides of the exhaust main mechanism, and a light source mechanism is installed inside the back side of the exhaust main mechanism. The present application can pump the black oily liquid in the cabinet door mechanism through the pump liquid mechanism when observing, so that the inside of the liquid guide hollow glass plate is filled with nitrogen, the light transmission of the liquid guide hollow glass plate is ensured, and observation can be performed. When culturing, the inside of the liquid guide hollow glass plate is filled with black oily liquid pushed by the pump liquid mechanism, so that external light is difficult to penetrate, the device is ensured to be illuminated by the internal light source mechanism, so that light pollution from the outside is prevented from shining into the device during non-observation time, and the control effect of internal illumination variables is improved.

The application discloses a composition of Qixuebengzhi recipe and belongs to the field of traditional Chinese medicines; the composition is mainly prepared from bupleurum, immature fruit of citrus, persicae semen, safflower, chuanxiong and red peony root; the application is based on the concept of treating heart and body simultaneously, and through the ascending and descending of qi and the regulating of liver qi of bupleurum and immature fruit of citrus, the composition can dredge the liver and regulate qi, and through the dispersing of persicae semen and safflower, the composition can dredge the channels and remove stasis, and through the combination of chuanxiong and red peony root, the composition can regulate qi and blood, and the combination of the medicines can directly attack the core pathogenesis of qi stagnation and blood stasis; clinical verification shows that the composition can not only significantly improve the TCM syndromes such as chest pain and chest distress of patients and the frequency of angina pectoris attacks, but also quickly relieve anxiety and depression and improve sleep quality.

The application discloses a kind of Miao medicine composition for treating liver fibrosis and cirrhosis ascites and its preparation method and application, belong to traditional Chinese medicine and national medical technology field.The composition is made of specific weight ratio of chases yellow grass, pearl grass, white flower snake tongue grass, bupleurum, vinegar baked turtle shell, Miao medicine soft liver grass (dried whole grass of gold star fern), catpaw grass, rhizoma sparganii, zedoary, peach kernel, rehmannia, astragalus, atractylodes, angelica, salvia miltiorrhiza, calcined oyster, big belly skin, poria cocos, curcuma, prepared rehmannia, white peony root, chuanxiong.The application provides pill, granule, capsule and the like controllable preparation process, and the product quality is stable, and safety is high.Experiment and clinic confirm that the composition can significantly reverse liver fibrosis, quickly subsides cirrhosis ascites and reduces recurrence rate, simultaneously improves liver function, liver elasticity, serum albumin and blood coagulation function, is suitable for long-term treatment of liver fibrosis and cirrhosis ascites, and has good industrial application prospect.

The application belongs to the technical field of medicine, and particularly relates to a traditional Chinese medicine composition for treating cognitive impairment and a preparation method thereof. The preparation method of the traditional Chinese medicine composition comprises the following steps: S1. adding modified mesoporous silicon dioxide to water extracts of ginseng, poria cocos, polygala, acorus gramineus, bupleurum, radix curcumae, cyperus rotundus and chuanxiong, grinding, vacuum drying, and preparing an intermediate product; and S2. mixing the intermediate product with microcrystalline cellulose, mannitol, sodium carboxymethyl starch and a stabilizer, adding a binder, extruding and rounding, drying, sieving, and preparing the traditional Chinese medicine composition. The method is simple in steps and easy to put into production. The obtained traditional Chinese medicine composition can significantly improve the oxidative stress damage of a vascular dementia model rat.

The application discloses a traditional Chinese medicine hair blackening ointment preparation for syndrome differentiation and classification. The application provides a specific compounding scheme for three different syndromes of kidney deficiency type, blood heat type and liver stagnation type. The preparation takes prepared rehmannia root, madder, angelica, female privet fruit and cypress leaf as basic raw medicinal materials; on the basis, black sesame seed and medlar are added as the first auxiliary medicine for the kidney deficiency type, chrysanthemum and mulberry leaf are added as the second auxiliary medicine for the blood heat type, and bupleurum and bergamot are added as the third auxiliary medicine for the liver stagnation type. The application realizes the personalized and accurate treatment of the white hair disease by combining the syndrome differentiation and classification theory of traditional Chinese medicine, and improves the white hair problems of different constitutions through the personalized synergistic mechanism of kidney tonification and essence filling, blood nourishing and blood activating, blood cooling and hair blackening, and liver soothing and qi regulation. The white hair disease problems are solved from the internal conditioning, the medicinal materials and auxiliary medicines are all homologous varieties of medicine and food, are safe and non-toxic, are suitable for long-term use, and the preparation process is simple, and the effective rate is greatly improved compared with the general ointment.

The present application provides a kind of traditional Chinese medicine composition for improving damp-heat type skin yellow turbidity, it is composed of the following weight parts of raw materials: 5-8 parts of wine-fried gentiana scabra, 12-18 parts of wine-fried scrophularia, 12-18 parts of wine-fried gardenia, 12-18 parts of alisma, 12-18 parts of akebia, 12-18 parts of psyllium, 12-18 parts of wine-fried angelica, 18-25 parts of raw rehmannia, 12-18 parts of bupleurum, 8-12 parts of fried licorice, 12-18 parts of poria, 12-18 parts of cortex meliae, 12-18 parts of white atractylodes, 12-18 parts of white peony root.The present application has the core efficacy of clearing and draining liver and gallbladder dampness, enhances the efficacy of invigorating spleen, nourishing blood, softening liver and directly improving skin performance, thereby more safely and effectively improving liver and gallbladder dampness and spleen deficiency and blood weakness type skin yellow turbidity problem.

The present application relates to a kind of purposes of traditional Chinese medicine composition based on Liyu Shengxian decoction in the preparation of treating qi deficiency and blood stasis type lung nodule drug, it is related to the technical field of traditional Chinese medicine, by weight parts, the traditional Chinese medicine composition is made from following raw materials: 15-21 parts of radix astragali, 9-17.5 parts of angelica stem, 7-10 parts of frankincense, 7-10 parts of myrrh, 3-5 parts of cinnamomum cassia tip, 3-5 parts of bupleurum.In the basis of Liyu Shengxian decoction, the present application finds that omits zhi mu in original formula, adjusts the dosage relationship of radix astragali and angelica stem two and optimizes preparation process, by clinical verification, the treatment effect of qi deficiency and blood stasis type lung nodule patient can be significantly improved.Therefore, the present application provides a kind of traditional Chinese medicine composition based on Liyu Shengxian decoction for treating qi deficiency and blood stasis type lung nodule, can be further made into dosage forms such as traditional Chinese medicine honeyed pill and applied to the clinical treatment of qi deficiency and blood stasis type lung nodule disease, formula is simple, treatment effect is good, and application prospect is wide.

This utility model discloses a processing equipment for Polygonum multiflorum, belonging to the field of pharmaceutical equipment. It mainly consists of a tank (1), a hanging basket (2), a spray system (3), a hydraulic device (4), a condenser (5), a circulation pipeline (6), and a pump set (7). This utility model innovatively designs and expands the functions of existing Polygonum multiflorum processing equipment. By setting up novel structures such as a "spray system," "circulation pipeline," and "pump set," Polygonum multiflorum can fully absorb black bean juice, thus achieving uniform steaming and reducing toxicity while increasing efficacy. This utility model has a simple structure, is easy to operate, energy-saving, and environmentally friendly, making it suitable for large-scale industrial production.

This invention relates to the field of vinegar brewing technology, specifically to a functional vinegar for influenza prevention. Its composition includes the following raw materials: sorghum, barley, peas, honeycomb extract, red dates, peanuts, licorice, bupleurum, hawthorn, white sugar, prickly pear, yeast β-glucan, inulin, and a zinc source. This invention uses sorghum, barley, and peas to construct a grain-based complex fermentation base, and introduces red dates, hawthorn, licorice, and peanuts to form a synergistic flavor system. The two-phase blending is achieved through the first-phase extraction of red dates and hawthorn and the second-phase extraction of licorice, improving the initial fruity acidity and the subsequent sweet and full-bodied flavor. Furthermore, the combination of honeycomb extract, prickly pear, yeast β-glucan, inulin, and a zinc source, along with a segmented fermentation and low-temperature post-addition process, reduces heat sensitivity and loss of functional components, improving product stability and palatability. This achieves a synergistic enhancement of flavor harmony, nutritional support, and improved immunity, giving it the potential to prevent influenza.

The application discloses a socket type seeding device for organic bupleurum planting and a seeding method thereof, and relates to the technical field of organic bupleurum planting seeding devices. The device comprises a traction frame, rollers uniformly distributed at the bottom of the traction frame, a connecting plate driven to move in translation by the rollers, a punching assembly moving periodically following the connecting plate, a seeding assembly seeding seeds at different depths following the connecting plate, and a rotating ring moving adaptively following the seeding assembly. A plurality of groups of poking rods are fixedly connected to the bottom of the rotating ring and move adaptively following the rotating ring. The device drives the punching assembly to move downward to punch holes in the grass-proof cloth through the rotation of the rollers and the rotating plate. The soil on the inner wall of the seeding hole is poked, so that when the connecting plate drives the connecting pipe to move upward, the seeds are covered with soil step by step, thereby achieving the effect of seeding bupleurum seeds at different depths.

The application discloses a kind of external use traditional Chinese medicine formula for mastalgia and preparation method, belong to traditional Chinese medicine compound preparation field.This formula is composed of Raphanus sativus L., perilla seed, white mustard seed, Evodia rutaecarpa, cyperus rotundus and bupleurum.The subcritical fluid extraction method is used to extract mixed seed oil from Raphanus sativus L., perilla seed and white mustard seed, and then alcohol reflux extraction is used to obtain alcohol extraction infusion from cyperus rotundus, bupleurum and Evodia rutaecarpa.The mixed seed oil is made into microemulsion with surfactant and cosurfactant, and then the alcohol extraction infusion is mixed with gel matrix.Finally, the microemulsion is mixed with gel matrix to be homogeneous, defoamed, and microemulsion gel is prepared.The traditional Chinese medicine extract is prepared into microemulsion gel in the application, which combines high transdermal absorption rate of microemulsion and good spreadability of gel, has the effects of soothing liver and regulating qi, warming meridians and dispelling cold, resolving phlegm and resolving mass, can effectively relieve mastalgia, and the preparation method is stable and reliable with little skin irritation.

The application provides a traditional Chinese medicine composition for treating age-related macular degeneration, which is made of raw medicinal materials: Astragalus, Angelica sinensis, Ligustrum lucidum Ait, Scrophularia, Bupleurum, Radix Paeoniae Alba, Radix Rehmanniae, Pericarpium Citri Reticulatae, Coix, Fructus Aurantii, Forsythia. Clinical research shows that the traditional Chinese medicine composition can obviously improve the EDTRS letter number of the treatment group, and the total effective rates of Amsler table and visual field change after 6 months of treatment are 86.66% and 76.67% respectively.

The application discloses a traditional Chinese medicine composition for treating novel coronavirus infection and a preparation method, application and medicine thereof, and belongs to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition is composed of aconite, dried ginger, licorice, bupleurum, radix scrophulariae, pinellia, ginseng, jujube, raw ginger, white peony root, cassia twig, ephedra, gypsum, schisandra chinensis and asarum; the weight ratio of the aconite, bupleurum, radix scrophulariae, pinellia, white peony root, schisandra chinensis and asarum is 3-50:15-35:5-15:20-45:6-18:5-15:3-15; and the weight ratio of the dried ginger, raw ginger, cassia twig and ephedra is 12-45:1-5:3-15:3-15. Compared with the prior art, the traditional Chinese medicine composition has better anti-SARS-CoV-2 virus activity and has potential value for developing an anti-novel coronavirus.

The application discloses a traditional Chinese medicine composition for clearing heat and resolving toxins, benefiting the throat and eliminating swelling, and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: Houttuynia cordata 10-20 parts, Astragalus root 8-15 parts, Andrographis 8-15 parts, Figwort 8-15 parts, Platycodon 8-15 parts, Monotropa 8-15 parts, Honeysuckle 2-6 parts, Bupleurum 2-6 parts, Belamcanda 2-6 parts, Peucedanum 2-6 parts, Marsh Marigold 1-4 parts and artificial ox gall 0.1-0.6 parts. The traditional Chinese medicine composition has the effects of clearing heat and resolving toxins, benefiting the throat and eliminating swelling, relieving cough and reducing sputum, and is used for treating fever caused by wind-heat invading the lung and lung heat being in excess, nasal discharge of sticky or yellow phlegm, sore throat, cough and expectoration, yellow and thick sputum, headache and body pain, red tongue and yellow tongue fur and the like, and is also used for treating influenza, acute upper respiratory tract infection, acute pharyngitis, tonsillitis and the like. The effect is better than that of each proportion.

The present application discloses a kind of liver-softening and depression-relieving soft sweets and a preparation method thereof, and belongs to the technical field of health-care food.The soft sweets are composed of more than ten kinds of Chinese medicinal materials such as Bupleurum, Radix Paeoniae Alba, Poria cocos, rose, and gelatin, malt syrup and citric acid.The preparation method adopts a subsection extraction and low-temperature concentration process, which maximally retains active ingredients and rose fragrance.The product innovatively combines traditional Chinese medicine with soft candy dosage form, has clear effects of liver-softening and depression-relieving and tranquilizing, effectively masks the unpleasant flavor of Chinese medicine, and has a Q elastic and refreshing taste, a coordinated flavor, a moderate sour and sweet taste, an excellent sensory evaluation, a high consumer acceptance, a good stability and a high safety, thereby providing a delicious, convenient and effective health-care food for relieving emotional stress and sleep problems.

The application discloses a traditional Chinese medicine composition suitable for preventing female breast hyperplasia and dissipating breast nodules and a traditional Chinese medicine breast patch, and belongs to the technical field of external preparations of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from Chinese herbal medicines of the blood-activating and stasis-dissolving type, the liver-soothing and qi-regulating type, the heat-clearing and swelling-dissolving type and the deficiency-tonifying and regulating type, such as Bupleurum, Radix Curcumae, etc., and is prepared into small-molecule extracts below 3kDa after composite fermentation of Lactobacillus plantarum and Bacillus subtilis and composite enzymolysis of cellulase, etc.; the traditional Chinese medicine breast patch is prepared into a paste from the composition, transdermal adjuvants, humectants and the like, and is coated on a base of a composite breathable non-woven fabric of bamboo fiber, wormwood fiber and viscose fiber. The application has scientific formula, treats both symptoms and root causes, has good transdermal absorption effect of small-molecule extracts, is comfortable and non-irritating in patching, can quickly relieve breast distending pain and dissipate breast nodules, can also strengthen body resistance and reduce the recurrence rate, is safe and reliable, is suitable for female patients with various benign breast diseases, is especially suitable for patients intolerable to oral administration, and is easy to be industrially produced.