240 results about "Bupleurum" patented technology

The invention discloses a traditional Chinese medicine composition, a preparation method thereof and an application of the traditional Chinese medicine composition in preparation of a medicine for preventing and treating ovarian reserve hypofunction, and belongs to the technical field of traditional Chinese medicines. The composition is prepared from the following raw materials in parts by weight: 10 to 15 parts of radix paeoniae alba, 6 to 10 parts of radix bupleuri, 10 to 15 parts of radix rehmanniae preparata, 15 to 30 parts of stir-fried rhizoma dioscoreae, 12 to 20 parts of semen cuscutae, 10 to 12 parts of radix angelicae sinensis, 10 to 15 parts of poria cocos, 12 to 25 parts of fructus ligustri lucidi, 10 to 15 parts of radix salviae miltiorrhizae, 10 to 15 parts of fructus corni and 10 to 15 parts of radix morindae officinalis. The traditional Chinese medicine composition can obviously reduce the level of follicle-stimulating hormone (FSH) of cis-platinum model mice, increase estradiol (E2), increase the number of follicles at all levels, especially the number of primordial follicles, and reduce the number of atresia follicles; the ovarian function of naturally aged mice can be improved, FSH (follicle stimulating hormone) is reduced, anti-mullerian hormone (AMH) and E2 are increased, and the quantity of follicles at all levels, especially the quantity of corpus luteum, primordial follicles and anterior sinus follicles, is increased; therefore, the composition disclosed by the invention has an obvious protection effect on the hypoovarian reserve function.

The invention belongs to the field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition for treating liver depression and spleen deficiency syndrome metabolism-related fatty liver disease, which is prepared from the following raw materials in parts by weight: 8 to 10 parts of ginseng, 10 to 15 parts of radix bupleuri, 10 to 15 parts of radix curcumae, 6 to 9 parts of ginger processed pinellia, 6 to 10 parts of fructus amomi, 10 to 15 parts of rhizoma atractylodis, 10 to 15 parts of poria cocos, 10 to 15 parts of semen hoveniae, 10 to 15 parts of radix rehmanniae, 8 to 10 parts of rhizoma polygoni cuspidati and 6 to 9 parts of lignum dalbergiae odoriferae. The traditional Chinese medicine composition is used for treating the metabolism-related fatty liver diseases from the aspects of liver depression, spleen deficiency and phlegm-blood stasis, starts from the core pathological chain of liver depression, spleen deficiency, phlegm-dampness and blood stasis, has the functions of soothing the liver, tonifying the spleen, resolving dampness, reducing fat and promoting blood circulation to remove meridian obstruction, and is particularly suitable for patients with liver depression, spleen deficiency and metabolism-related fatty liver diseases. Clinical tests prove that the traditional Chinese medicine composition has a good treatment effect on patients with liver depression and spleen deficiency syndrome metabolism-related fatty liver diseases, the total effective rate reaches 94% or above, and the traditional Chinese medicine composition is mild in medicine property, good in safety, stable in curative effect, not prone to relapse and suitable for being taken for a long time.

The invention discloses a pharmaceutical composition for preventing and treating chronic atrophic gastritis. The pharmaceutical composition is prepared from the following raw materials in the following weight ratio: 14-18 parts of peach kernel, 10-14 parts of Chuanxiong rhizome, 8-12 parts of Panax notoginseng, 6-10 parts of safflower, 20-28 parts of kelp, 10-14 parts of selfheal, 15-25 parts of codonopsis pilosula, 10-14 parts of atractylodes macrocephala, 12-16 parts of fructus aurantii, 8-12 parts of amomum villosum, 12-16 parts of bupleurum, 10-18 parts of citron, and 5-10 parts of fucoidan. The pharmaceutical composition is used to treat chronic atrophic gastritis of gastric collateral blood stasis type by promoting blood circulation and removing blood stasis, unblocking meridians and relieving pain, eliminating phlegm, softening and dispersing nodules, invigorating qi and promoting qi circulation, and soothing the liver and harmonizing the stomach. The invention also discloses a preparation method of the pharmaceutical composition.

The invention discloses a traditional Chinese medicine composition for treating chronic pelvic inflammation, which is prepared from the following raw materials: 8-16 parts of fried radix bupleuri, 8-16 parts of white peony root, 20-40 parts of astragalus membranaceus, 20-40 parts of radix pseudostellariae, 10-20 parts of poria cocos, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of angelica sinensis, 8-16 parts of ligusticum wallichii, 8-16 parts of mint, 8-16 parts of rhizoma cyperi, 8-16 parts of corydalis tuber, 8-16 parts of fried endothelium corneum gigeriae galli, 8-16 parts of salvia miltiorrhiza, 8-16 parts of sargentgloryvine stem, 8-16 parts of patrinia and 4-8 parts of liquorice. The traditional Chinese medicine is especially suitable for treating qi deficiency and blood stasis type chronic pelvic inflammation.

The invention provides a traditional Chinese medicine composition for treating acute altitude sickness. The traditional Chinese medicine composition is prepared from ginseng, astragalus membranaceus, acanthopanax, rhodiola rosea, turnip, salvia miltiorrhiza, dogwood, poria cocos, rhizoma cimicifugae, radix bupleuri, platycodon grandiflorum, aster, elecampane, rhizoma anemarrhenae and liquorice. The traditional Chinese medicine composition disclosed by the invention can be used for treating the acute altitude sickness, remarkably prolonging the load-bearing swimming time of rats, remarkably increasing the arterial oxygen partial pressure and the arterial oxygen saturation of acute altitude sickness model rats and relieving physical fatigue, has obvious effects of resisting anoxia, improving acid-base balance and resisting inflammation, and has obvious curative effects on myocardial injury, liver injury, liver injury and the like. And the kidney injury can be protected.

The invention belongs to the technical field of veterinary drug compositions, and particularly relates to a veterinary drug composition containing traditional Chinese medicine ingredients, which comprises the following raw materials in variety and proportion: 8-15 parts of honeysuckle, 3-6 parts of fructus forsythiae, 6-9 parts of coptis chinensis, 12-20 parts of chrysanthemum, 6-8 parts of semen plantaginis, 7-10 parts of lygodium japonicum, 6-10 parts of houttuynia cordata, 10-13 parts of radix bupleuri, 3-7 parts of pseudo-ginseng, 6-12 parts of salvia miltiorrhiza, 6-8 parts of subprostrate sophora and 12-20 parts of sculellaria barbata. According to the veterinary medicine composition containing the traditional Chinese medicine components, by selecting honeysuckle, fructus forsythiae, coptis chinensis, chrysanthemum, semen plantaginis, lygodium japonicum, houttuynia cordata, radix bupleuri, pseudo-ginseng, salvia miltiorrhiza, subprostrate sophora and sculellaria barbata, the effects of clearing away heat and toxic materials, stopping diarrhea and dysentery, cooling blood and dispelling wind, nourishing yin and moistening dryness, strengthening the body resistance to eliminate pathogenic factors and expelling and killing insects of the composition can be guaranteed; and by arranging the stabilizer, the cosolvent and the preservative, the state stability and the service life of the composition can be guaranteed.

The application belongs to the technical field of traditional Chinese medicines, and particularly relates to a preparation method of a traditional Chinese medicine composition for intractable chronic cough and application thereof; and particularly discloses a traditional Chinese medicine composition for treating intractable chronic cough, which comprises, by weight fraction, 10-40 parts of Poria cocos, 3-25 parts of fried licorice, 3-20 parts of Schisandra chinensis, 1-20 parts of dried ginger, 1-12 parts of Asarum, 3-20 parts of prepared pinellia, 3-20 parts of bitter apricot kernel, 5-40 parts of white mulberry bark, 3-25 parts of bupleurum, 3-25 parts of wind-protecting plant, 5-40 parts of north-sand peony and 1-5 pieces of centipede. The application is a pure traditional Chinese medicine prescription, has high safety and good efficacy, and can quickly relieve symptoms of intractable chronic cough patients, and is suitable for clinical popularization and application due to wide drug source.

The invention relates to the field of organic radix bupleuri seedling planting, and discloses an automatic organic radix bupleuri seedling transplanting device which comprises a frame, the bottom of the frame is fixedly connected with driving wheels, the top of the frame is provided with a storage box mechanism, and the storage box mechanism is used for placing and storing organic radix bupleuri seedlings needing to be transplanted; a punching mechanism is arranged on the inner wall of the frame, and the punching mechanism is used for punching soil in the transplanting process; the punching mechanism is in sliding connection with the inner wall of the vehicle frame through a sliding plate mechanism, and the sliding plate mechanism is used for driving the punching mechanism to transversely move along the interior of the vehicle frame. Through linkage design of the punching mechanism and the rack mechanism, precise cooperation of punching and seedling feeding is realized, the problem of poor continuity caused by mismatching of punching and seedling feeding rhythms of traditional equipment is solved, it is ensured that seedlings can timely and accurately fall into a planting groove after the planting groove is formed, and the transplanting efficiency is improved.

The traditional Chinese medicine comprises the following raw materials in parts by weight: 15g of codonopsis pilosula, 10g of rhizoma acori graminei, 10g of processed polygala tenuifolia, 15g of rhizoma smilacis glabrae, 12g of raw dens draconis, 10g of astragalus membranaceus, 9g of divaricate saposhnikovia root, 10g of bighead atractylodes rhizome, 6g of raw liquorice, 9g of ephedra, 9g of almond, 15g of gypsum, 9g of cassia twig, 9g of rhizoma alismatis, 10g of radix bupleuri, 6g of scutellaria baicalensis, 9g of ginger processed pinellia, 9g of ginger, 9g of aster tataricus, 9g of flos farfarae, 9g of blackberry lily, 3g of asarum, 10g of parched white peony root, 9g of immature bitter orange and 9g of pericarpium citri reticulatae. According to the traditional Chinese medicine for detoxifying and clearing away the lung-heat and the decocting method thereof, the prescription medicine is designed from integrity, prevention and treatment are carried out at the same time, all the prescription medicines adopt non-toxic and harmless top-grade traditional Chinese medicine raw materials recorded in Pharmacopoeia, medicinal materials with bitter, cold and severe nature and taste are reduced as much as possible, damage to yang qi in a body is avoided, and the traditional Chinese medicine is safe and reliable. Therefore, the traditional Chinese medicine composition can meet the requirements of preventing and treating pneumonia in the aspects of safety, reasonability and effectiveness.

The invention discloses a compound plant extract for relieving heat stress of dairy cows. The compound plant extract is prepared from the following components in parts by weight: 33 parts of radix bupleuri polysaccharide, 28 parts of lentinan, 22 parts of dihydromyricetin and 17 parts of chlorogenic acid. The invention also discloses a preparation method of the compound plant extract for relieving heat stress of dairy cows. According to the compound plant extract for relieving the heat stress of the dairy cow, disclosed by the invention, the radix bupleuri polysaccharide, the lentinan, the dihydromyricetin and the chlorogenic acid in different parts by weight are added, and the compound plant extract is added into a daily basal feed for feeding the dairy cow, so that the rectum temperature of the heat stress dairy cow can be remarkably reduced, the milk yield of the dairy cow is increased, and the immunity and the antioxidant capacity of the dairy cow are improved; therefore, the heat stress reaction of the dairy cow is greatly relieved.

The application belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating abdominal distension and diarrhea of cold-heat complex type and a preparation method thereof. The technical scheme points of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 3-6 parts of perilla, 3-10 parts of dried ginger, 3-12 parts of eucommia, 3-10 parts of scrophularia, 2-6 parts of coptis, 10-20 parts of fried coix seed, 6-10 parts of clear pinellia, 3-10 parts of dried tangerine or orange peel, 10-15 parts of poria, 6-10 parts of wheat-cooked atractylodes, 6-10 parts of vinegar-cured corydalis, 6-10 parts of vinegar-cured bupleurum, 6-10 parts of pericarpium zephyritae, 6-10 parts of chuanxiong, 6-10 parts of magnolia officinalis, 6-10 parts of fried hawthorn fruit, 3-6 parts of platycodon, and 3-10 parts of fried licorice. The traditional Chinese medicine composition and the traditional Chinese medicine water pill prepared from the traditional Chinese medicine composition have the effect of treating abdominal distension and diarrhea of cold-heat complex type.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating insomnia and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw material components in parts by weight: 7 to 11 parts of radix bupleuri, 7 to 11 parts of radix curcumae, 10 to 15 parts of radix codonopsis, 8 to 12 parts of rhizoma atractylodis macrocephalae, 4 to 8 parts of rhizoma pinelliae, 4 to 8 parts of caulis bambusae in taeniam, 12 to 18 parts of bulbus lilii, 8 to 13 parts of radix ophiopogonis, 10 to 14 parts of radix salviae miltiorrhizae, 12 to 18 parts of fossil fragments, 13 to 17 parts of nacre mother of pearl and 4 to 8 parts of radix glycyrrhizae preparata. The traditional Chinese medicine composition takes liver soothing, spleen strengthening, phlegm reducing and nerve calming as the core, has the effects of nourishing yin and activating blood, and regulates the function of a human body from multiple aspects through the synergistic effect of multiple medicinal materials, so that the effect of improving the sleep quality is achieved, and the adverse reaction rate is lower than that of a Western medicine benzodiazepine medicine.

The invention discloses a traditional Chinese medicine composition for treating sepsis as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from 1-15 parts of sulfur, 3-25 parts of calamitas urinae hominis, 1-20 parts of wine-treated rhubarb, 10-30 parts of fructus cannabis, 10-50 parts of radix bupleuri, 5-30 parts of scutellaria baicalensis, 5-25 parts of folium isatidis, 5-25 parts of peach kernels, 5-30 parts of salvia miltiorrhiza, 5-30 parts of angelica sinensis, 5-30 parts of sophora flower charcoal, 5-25 parts of fructus gardeniae praeparatus and 5-60 parts of wine-treated fructus corni. According to the invention, through a combined mode of'monarch drug targeted oral administration and synergistic decoction of minister, assistant and guide drugs', the whole-course intervention of'upstream inhibition, midstream blocking and downstream regulation 'on sepsis immune disorder can be realized, meanwhile, the functions of warming yang, dispelling cold, cooling blood and detoxifying are taken into account, and the pro-inflammatory / anti-inflammatory balance is successfully recovered to a physiological state; the action mode is superior to that of a traditional single anti-inflammatory strategy and a traditional Chinese medicine application mode of whole-prescription decoction. In a standard animal model, the traditional Chinese medicine composition definitely shows the dose-dependent extremely remarkable effects of anti-inflammation, immunoregulation, multi-organ protection and overall condition improvement, the curative effect of a high-dose group of the traditional Chinese medicine composition is equivalent to that of a classic potent medicine, and the traditional Chinese medicine composition has more advantages in the aspects of recovering immune homeostasis, warming yang and strengthening the body resistance.

The invention discloses a traditional Chinese medicine composition for treating acute pharyngitis as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The technical problems to be solved are that the traditional Chinese medicine composition for treating acute pharyngitis is not suitable for long-term administration, is not suitable for sensitive people and is easy to damage spleen and stomach. The invention provides a traditional Chinese medicine composition for treating acute pharyngitis. The traditional Chinese medicine composition is prepared from the following raw materials: honeysuckle flower, fructus forsythiae, radix isatidis, herba menthae, radix bupleuri, fructus arctii, schizonepeta spike, gypsum, radix scutellariae, fructus gardeniae, radix platycodonis, radix paeoniae rubra, rhizoma phragmitis, semen armeniacae amarae, herba lophatheri, fructus aurantii, radix saposhnikoviae, medicated leaven, stiff silkworm and liquorice root. The traditional Chinese medicine composition disclosed by the invention can inhibit inflammatory reaction by inhibiting phosphorylation levels of PI3K / AKT and RAS / MAPK signal pathways AKT and MAPK, so that acute pharyngitis is improved.

The invention provides a traditional Chinese medicine composition for improving the survival rate of piglets and a preparation method and application thereof, and belongs to the technical field of feed additives. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 6 to 10 parts of fructus forsythiae, 15 to 22 parts of radix isatidis, 15 to 22 parts of radix scutellariae, 8 to 12 parts of honeysuckle flower, 5 to 8 parts of herba taraxaci, 10 to 15 parts of rhizoma atractylodis macrocephalae, 8 to 12 parts of poria cocos, 6 to 10 parts of rhizoma dioscoreae, 12 to 18 parts of radix astragali seu hedysari, 8 to 12 parts of radix bupleuri, 5 to 8 parts of liquorice root and 3 to 6 parts of semen ziziphi spinosae. Based on the traditional Chinese medicine theory of supporting healthy energy and giving consideration to both symptoms and root causes, a three-dimensional synergistic system of clearing heat, resisting bacteria, invigorating spleen, benefiting intestines, tonifying qi and resisting stress is constructed to adapt to the physiological characteristics of weaned piglets, so that the problems of low survival rate, slow growth and substandard quality in weaned piglet breeding are solved, and the survival rate of the weaned piglets is remarkably improved.

The invention discloses a traditional Chinese medicine composition for preventing and treating atherosclerosis and plaque formation and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine components in parts by weight: 10-15 parts of peach kernel, 7-12 parts of safflower, 12-18 parts of angelica sinensis, 15-25 parts of radix rehmanniae, 12-18 parts of ligusticum wallichii, 10-15 parts of radix paeoniae rubra, 12-18 parts of radix cyathulae, 12-18 parts of platycodon grandiflorum, 12-18 parts of radix bupleuri, 10-15 parts of bran-fried fructus aurantii, 4-8 parts of honey-fried licorice root, 10-15 parts of ginseng, 8-12 parts of poria cocos, 4-8 parts of rhizoma zingiberis, 10-15 parts of rhizoma cyperi, 12-18 parts of radix curcumae, 10-15 parts of cortex albiziae, 12-18 parts of rhizoma pinelliae preparata, 12-18 parts of exocarpium citri grandis, 20-30 parts of 25 parts of allium macrostemon, 25-35 parts of corn stigma, 15-25 parts of plantain herb and 25-35 parts of oyster; based on the theory of traditional Chinese medicine, all traditional Chinese medicine raw materials are screened, and through the combined action of all the raw materials, the traditional Chinese medicine composition has a remarkable curative effect on atherosclerosis and takes effect quickly.

The application discloses a kind of oil-containing water body separation membrane for refining process of Bupleurum volatile oil and preparation method and application.The preparation method of the application is first mixed and dissolved according to proportion with cellulose acetate and cellulose nitrate powder, form casting membrane liquid, and the base membrane is prepared using non-solvent phase conversion method;Second, the film is deacetylated;After that, it is soaked in acyl chloride n-hexane solution for crosslinking;Finally, by in-situ hydrolysis of silane coupling agent on the membrane surface, a hydrophobic surface is prepared, and an oil-containing water body separation membrane for refining process of Bupleurum volatile oil is obtained.This method forms a hydrophobic layer on the surface of the membrane, which strengthens the rapid passage of Bupleurum volatile oil molecules and inhibits the penetration of water;Using the oil-containing water body separation membrane avoids the formation of emulsion during oil-water separation, showing high separation efficiency and stability, and widening the application of cellulose acetate membrane in traditional Chinese medicine preparation process.

The invention discloses an in-vitro rapid propagation bud cultivation method for bupleurum yutai, and belongs to the field of traditional Chinese medicinal material plant breeding. The method is realized by five steps of explant surface sterilization, cluster bud induction, proliferation and subculture, rooting and seedling hardening. Selecting a stem base bud as an explant, and sterilizing with 75% alcohol and mercury bichloride; different combinations and proportions of hormones such as 6-BA, IBA, NAA and ZT are utilized to improve the propagation coefficient of buds and realize rapid rooting of tissue culture seedlings, and seedling hardening is performed through peat and perlite (2: 1). According to the method, an efficient vegetative propagation system is established, the method is not limited by natural environment, cluster buds can be directly induced, the production period is shortened, the production cost is reduced, the plant inheritable character is stable, and the excellent quality and characteristics of stock plants are reserved. The method can rapidly breed a large number of aseptic seedlings, solves the difficult propagation problem of bupleurum yutai, meets the market demand, and has high application value.

The present application relates to a kind of traditional Chinese medicine composition for preventing and / or treating diabetes, preparation method and purposes.Component includes Astragalus membranaceus, Pueraria, Bupleurum, Ganoderma lucidum, Salvia miltiorrhiza.The water or alcohol extract preparation process of the present application is economical, simple, suitable for industrial large-scale production, and patient is convenient to take.The obtained extract has significant effect of regulating sugar and lipid metabolism, and can be applied to prepare medicine for preventing and treating diabetes.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating chronic refractory cough and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following fifteen traditional Chinese medicines in specific parts by weight: blackberry lily, roasted ephedra, asarum, bamboo juice pinellia ternate, raw liquorice, radix bupleuri, fried scutellaria baicalensis, fructus aurantii, platycodon grandiflorum, roasted perillaseed, almond, wild buckwheat, Japanese metaplexis pericarp, calyx seu fructus physalis and pericarpium trichosanthis. Aiming at the core pathogenesis of the chronic refractory cough, such as residual evil and turbidity and lung-qi obstruction, evil and turbidity are separately eliminated by a method of separately eliminating and discharging, and the lung-qi is diffused and restored. The traditional Chinese medicine composition is reasonable in component and remarkable in curative effect, clinical data shows that the traditional Chinese medicine composition can effectively improve core symptoms such as cough, expectoration and throat itching, no obvious adverse reaction is found, and safety is high.

The invention focuses on the problem of heavy metal residues in potato planting, and provides a traditional Chinese medicine agent for degrading potato heavy metal residues and a preparation method of the traditional Chinese medicine agent. The traditional Chinese medicine preparation is prepared from various traditional Chinese medicines such as radix bupleuri, radix scutellariae and fructus gardeniae according to a specific weight part ratio, and the finished product is prepared by decocting the traditional Chinese medicines and adding a proper amount of food-grade preservative through a unique preparation process. The working principle is based on multiple mechanisms such as soil microorganism synergy, plant resistance enhancement, enzyme activity recovery, material conversion and soil environment optimization. During application, the fertilizer is diluted according to a specific multiple and then is irrigated to root soil or applied through a drip irrigation system in the later period of potato flowering and the mature period. Compared with a traditional method, the traditional Chinese medicine preparation can effectively reduce the heavy metal residues of the potatoes, the preparation and use processes are green and environment-friendly, the cost is controllable, and a new way is provided for improving the quality of the potatoes and guaranteeing food safety.

The invention relates to the technical field of traditional Chinese medicine pharmacy, and discloses a traditional Chinese medicine composition for treating rhinitis based on a fructus xanthii extract and a preparation method of the traditional Chinese medicine composition. 5%-7% of liquorice; 15%-20% of dark plum; 2%-5% of bighead atractylodes rhizome; 20%-25% of schisandra chinensis; 1%-3% of almonds; 5%-8% of cortex mori radicis; 4%-11% of centipeda minima; 4%-7% of fructus chebulae; 0.2%-0.5% of cassia twig; 1%-3% of radix saposhnikoviae and 4%-9% of 4%-7% of radix astragali; 3%-6% of radix ophiopogonis; the raw materials are processed and proportioned, and the traditional Chinese medicine ointment is prepared through the processes of decoction of the detoxifying and synergistic group, concentration of the orifice-opening and exterior-strengthening group, extraction of the qi-tonifying and yin-nourishing group, mixed light decoction and concentration. When the ointment is used, a cotton swab is coated with the ointment, the cotton swab coated with the ointment is fed into the nasal polyp part of a rhinitis patient and stays for about 20 minutes, after the drug effect of the ointment is slowly released, the nasal polyp necroses, part of the nasal polyp can fall off after about 15 days, and the treatment process can be repeated for multiple times and once every 15 days until the nasal polyp completely falls off. The ointment can effectively relieve nasal obstruction, running nose, rhinocnesmus and sneezing symptoms of rhinitis patients; the traditional Chinese medicine is not required to take medicine but is only externally used, is very safe to use and has no toxic or side effect.

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating gallbladder and bile duct disease, which at least comprises the following components in parts by weight: 8-10g of radix curcumae, 14-16g of pericarpium trichosanthis, 5-7g of pericarpium citri reticulatae viride, 8-10g of fructus aurantii, 14-16g of raw endothelium corneum gigeriae galli, 27-33g of lysimachia christinae hance or 8-10g of fried radix bupleuri, 22-26g of fried white paeony root and 5-7g of liquorice. The preparation method of the traditional Chinese medicine composition for treating the gallbladder and bile duct disease comprises the following steps: mixing the raw materials, adding 400ml of clear water, boiling with strong fire, continuously decocting for 30 minutes, filtering and extracting liquid medicine; adding 400ml of clear water into medicine residues, boiling with strong fire, continuing to decoct for 30 minutes, filtering and extracting medicine liquid; and combining the medicine liquid extracted twice. The traditional Chinese medicine composition for treating the gallbladder and bile duct disease has the effects of soothing liver and regulating qi, benefiting gallbladder and removing stagnation, and relieving spasm and pain, and can effectively treat liver and gallbladder qi stagnation, stagnation and turbid stagnation type chronic cholecystitis and gallbladder polyp.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for relieving depression and clearing collaterals and a preparation, a pharmaceutical composition and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 6-12 parts of radix bupleuri, 9-15 parts of radix curcumae, 6-12 parts of rhizoma acori graminei, 3-9 parts of fructus gardeniae, 3-9 parts of polygala tenuifolia, 9-15 parts of radix paeoniae rubra and 9-20 parts of cortex albiziae. The traditional Chinese medicine composition provided by the invention can be used for remarkably improving depression-like behaviors of mice with depression, reversing synaptic injury and improving the expression of synaptic associated proteins SYP and PSD-95. The anti-depression mechanism of the traditional Chinese medicine composition is that the traditional Chinese medicine composition has the effects of synergistically inhibiting activation of microglial cells and reducing the level of proinflammatory cytokines such as Tnf alpha, Il1beta and Il6, so that neuroinflammation is remarkably inhibited, and the traditional Chinese medicine composition has the advantages of novel formula, definite mechanism and definite curative effect for treating depression, particularly patients with anxiety and dysphoria symptoms.

The invention discloses a traditional Chinese medicine composition for chronic obstructive pulmonary disease and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by mass: main medicines: 15-30 parts of radix rehmanniae preparata and 3-9 parts of semen allii tuberosi; auxiliary medicines: 10-30 parts of ginseng, 15-30 parts of astragalus membranaceus, 6-12 parts of ganoderma sinense, 6-12 parts of bighead atractylodes rhizome and 3-6 parts of schisandra chinensis; adjuvant drugs: 6-12 parts of radix ophiopogonis, 6-10 parts of rhizoma anemarrhenae, 6-10 parts of radix cyathulae and 6-10 parts of platycodon grandiflorum; and conductant drugs: 3-6 parts of radix bupleuri and 3-6 parts of rhizoma cimicifugae. The composition directly refers to the core pathogenesis of lung-kidney deficiency, the adjuvants reinforce lung and kidney tonifying, spleen strengthening and superficies consolidating, the adjuvants have the effects of nourishing yin, moistening dryness, reducing phlegm and activating blood, and the medicines prevent tonifying and stagnation, are orderly in lifting and descending and promote synergistic efficacy.

The invention discloses a traditional Chinese medicine composition for treating obesity phlegm-dampness obstructing spleen syndrome. Comprising the following raw material medicines in parts by weight: 18-25 parts of astragalus membranaceus, 11-15 parts of bighead atractylodes rhizome (fried), 11-15 parts of poria cocos, 8-12 parts of rhizoma alismatis, 3-5 parts of coptis chinensis (fried with wine), 4-6 parts of rheum officinale (fried with wine), 8-12 parts of semen cassiae (fried), 7-12 parts of radix bupleuri (fried with vinegar), 11-15 parts of hyperforin perforatum, 13-18 parts of oriental wormwood, 10-15 parts of salvia miltiorrhiza (fried with wine), 7-9 parts of curcuma zedoary (fried with vinegar), 7-10 parts of polygonum cuspidatum, 14-20 parts of herba epimedii (fried), 6-8 parts of rhizoma zingiberis and 10-15 parts of glossy privet fruit (steamed with wine). The traditional Chinese medicine composition is prepared from 14-20 parts of prepared rehmannia roots, 18-25 parts of hawthorn fruits, 10-15 parts of lotus leaves, 8-12 parts of mulberry twigs, 7-9 parts of baikal skullcap roots (roasted with wine), 8-12 parts of polygala roots, 10-15 parts of kudzuvine roots and 7-9 parts of licorice roots (roasted). The traditional Chinese medicine composition is researched and developed on the basis of complex pathogenesis and pathogenesis of the obesity phlegm-dampness obstructing spleen syndrome, and has an expected effect of treating the obesity phlegm-dampness obstructing spleen syndrome.

The invention discloses an anti-hepatic fibrosis traditional Chinese medicine compound preparation and application thereof.The anti-hepatic fibrosis traditional Chinese medicine compound preparation is prepared from herba artemisiae scopariae, parched fructus gardeniae, roasted rhizoma atractylodis macrocephalae, turtle shells, radix bupleuri, rhizoma corydalis, herba desmodii styracifolii and herba scutellariae barbatae, all the medicines are compatible and have a synergistic effect, and the effects of clearing heat and promoting diuresis, promoting blood circulation to remove blood stasis, softening hardness to dissipate stagnation and tonifying spleen and qi are achieved together; the liver fibrosis is intervened from a plurality of target spots. Heat clearing and diuresis promoting can eliminate damp-heat evil damaging the liver; blood circulation of the liver can be improved by promoting blood circulation to remove blood stasis, and blood stasis is eliminated; the liver fibrosis hyperplasia can be resisted by softening hardness to dissipate stagnation, and the liver tissue hardening trend can be reversed; spleen invigorating and qi replenishing can enhance healthy qi of the body and improve the self-repairing ability of the liver. The multi-target and all-around treatment mode not only conforms to the holism concept of traditional Chinese medicine, but also conforms to the understanding of modern medicine on multi-factor and multi-link pathogenesis of hepatic fibrosis.

The invention provides a traditional Chinese medicine composition for treating cough variant asthma and application thereof, and belongs to the field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from radix bupleuri, herba ephedrae, herba schizonepetae, semen armeniacae amarae, radix platycodonis, fructus aurantii immaturus, exocarpium citri grandis, rhizoma phragmitis, rhizoma pinelliae, rhizoma belamcandae, the traditional Chinese medicine composition can obviously improve the condition of weight loss of guinea pigs after combined molding of ovalbumin and capsaicin, reduces the cough frequency and the lung focus area, effectively inhibits inflammatory factors, and can reach the treatment level equivalent to that of montelukast sodium.

The present invention belongs to the technical field of yolk antibody preparation, and specifically relates to an IBD yolk antibody microsphere and a preparation method thereof. The method uses polygonatum polysaccharide, IBD yolk antibody and bupleurum essential oil as the inner phase of the microsphere, and polylactic-co-glycolic acid copolymer as the outer phase. The special structure of the microspheres prepared by the present invention is conducive to presenting yolk antibodies and polygonatum polysaccharide to immune-competent cells. Phagocytic cells engulf the microspheres and can destroy the shell structure of the microspheres, releasing yolk antibodies and polygonatum polysaccharide, neutralizing the IBD virus infected by the body, playing a preventive and protective role for chickens not infected with IBD, and quickly controlling the condition of chickens infected with IBD.