77results about How to "Significant clinical effect" patented technology

The invention provides an anti-human CD117 monoclonal antibody and an application thereof. The anti-human CD117 monoclonal antibody comprises three heavy chain complementary determining regions CDR-H1, CDR-H2 and CDR-H3 and three light chain complementary determining regions CDR-L1, CDR-L2 and CDR-L3, the amino acid sequence of the CDR-H1 is as shown in SEQ ID NO: 1, the amino acid sequence of the CDR-H2 is as shown in SEQ ID NO: 2, the amino acid sequence of the CDR-H3 is as shown in SEQ ID NO: 3, the amino acid sequence of the CDR-L1 is as shown in SEQ ID NO: 4, the amino acid sequence of the CDR-L2 is as shown in SEQ ID NO: 5, and the amino acid sequence of the light chain complementary determining regions is as shown in SEQ ID NO: 6. The amino acid sequence of the CDR-L3 is as shown in SEQ ID NO: 6. Compared with the existing known anti-human CD117 monoclonal antibody, the antibody disclosed by the invention shows better cellular level biology, and is expected to show a good clinical effect in the aspect of preventing and treating related diseases.

The invention relates to the technical field of medical recommendation, in particular to a personalized nutrition treatment knowledge base construction method and system for critical patients. The system is used for acquiring basic information, medical record information, laboratory examination data and period diet intake information corresponding to critical patients, performing critical case entity construction, and generating case entity descriptors of the critical patients; constructing a corresponding personalized nutrition treatment initial knowledge base for each critical patient case entity descriptor in combination with a semantic knowledge association ratio between related scientific research literatures; obtaining clinical pathological characteristics and nutrition treatment knowledge entities, performing nutrition demand analysis and administration opportunity determination, and performing nutrition administration effect conflict evaluation to obtain a clinical nutrition administration-diet effect conflict ratio; and performing nutrition treatment knowledge updating optimization on the personalized nutrition treatment initial knowledge base to generate a personalized nutrition treatment knowledge optimization base. Accurate nutrition support can be provided for critical patients.

The invention discloses a bone cement composite material with collapse resistance and a preparation method thereof, and belongs to the technical field of biomedical materials. The composite material comprises a solid phase part and a liquid phase part, the liquid phase part and the solid phase part are mixed according to the liquid-solid ratio of 0.35 mL / g to 0.6 mL / g; the solid phase part is composed of calcium sulfate powder and calcium phosphate powder, and the mass ratio of the calcium sulfate powder to the calcium phosphate powder is 85: 15; the liquid phase part is selected from carboxymethyl chitosan or a combination of carboxymethyl chitosan and sodium alginate. The bone cement composite material prepared by the preparation method disclosed by the invention has good biocompatibility; due to a gel network formed by carboxymethyl chitosan and sodium alginate, the compressive strength of the bone cement is remarkably improved, and the collapse resistance and injectable performance are excellent; meanwhile, the bone cement composite material promotes the attachment and proliferation of osteoblasts, and can induce osteogenic differentiation in vitro.

The invention discloses a deeply-curable zirconia-containing dental repair resin and a preparation method thereof.The preparation method comprises the steps that a double-bond-containing silane coupling agent is added into a zirconia dispersion liquid and a silicon dioxide dispersion liquid respectively, modification reaction is conducted in the stirring state, and a modified solution # imgabs0 # and a modified solution II are obtained; carrying out spray drying on the modified solution I and the modified solution II through a three-fluid spray head to obtain a zirconium oxide and silicon oxide nanocluster body; uniformly mixing and stirring the zirconium oxide and silicon oxide nanocluster with a methacrylate organic matrix and a photoinitiator; and carrying out light curing treatment on the mixture to obtain the zirconium oxide dental repair resin. The zirconium oxide dispersion liquid, the silicon dioxide dispersion liquid and the three-fluid spray head are matched, the mechanical performance is improved on the premise that the X-ray radiation resistance and the effective curing depth are guaranteed, the dependence of the industry on zinc oxide, barium oxide and strontium oxide is broken through, the problem that a zirconium oxide material cannot be deeply cured due to the high refractive index is solved, and the application prospect is good.

The present invention provides a Chinese medicine composition for treating IgA nephropathy and a preparation method thereof, and belongs to the technical field of Chinese medicine compositions. The Chinese medicine composition of the present invention comprises raw rehmannia, astragalus, caesalpinia, codonopsis, radix rehmanniae, ophiopogon, plantago, tuckahoe, scutellaria, umbellate, motherwort, bupleurum, oldenlandia diffusa, scutellaria barbata, caulis scabra, radix scutellariae, radix scutellariae, radix licorice. The present invention also provides a preparation method of the Chinese medicine composition, comprising: weighing the raw materials according to the raw material ratio, decocting with water, and filtering to obtain a medicinal liquid. The composition provided by the present invention has a mild medicinal property, clears the heart fire, replenishes qi and yin, has no toxic side effects, can effectively reduce hematuria, proteinuria and adverse drug reactions, and is used for the treatment of chronic glomerulonephritis (IgA nephropathy).

The invention provides an asymmetric adhesive biological patch as well as a preparation method and application thereof. Specifically, the present disclosure provides an asymmetric adhesion biopatch comprising a substrate having a cellosilk structure, and an adhesive layer derived from an adhesive composition comprising a monomer, a photoinitiator, and a crosslinking agent, and having a cross-linking agent and a photoinitiator, the adhesive composition also includes an antibiotic compound and / or an ingredient providing active metal ions. The asymmetric adhesion biological patch provided by the invention provides a new choice for improving the clinical effect of dura mater repair.

This invention provides an ophthalmic gel composition comprising (1) ropinirole or a pharmaceutically acceptable salt thereof, (2) one or more thickeners, and other pharmaceutically acceptable excipients, wherein the viscosity of the ophthalmic gel composition is ≥100 mPa·s. The ophthalmic gel composition increases the viscosity of the product, prolonging the adhesion time of ropinirole to the eye. Compared with other dosage forms, it achieves both rapid onset of action and convenient administration, greatly enhancing its clinical value as an emergency medication.

The invention provides a tranquilizing traditional Chinese medicine application composition for treating endocrine insomnia and anxiety and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-25 parts of cinnamon, 6-10 parts of coptis chinensis, 10-15 parts of fructus evodiae, 10-20 parts of fructus psoraleae, 8-10 parts of scutellaria baicalensis, 10-20 parts of gordon euryale seeds, 20-25 parts of lily, 10-20 parts of spina date seeds, 5-10 parts of angelica sinensis, 3-7 parts of polygala tenuifolia, 5-15 parts of vine of multiflower knotweed, 3-5 parts of longan aril and 2-5 parts of nacre mother of pearl. The tranquilizing traditional Chinese medicine application composition for treating endocrine insomnia and anxiety provides a new choice for endocrine insomnia and anxiety, and the preparation method of the tranquilizing traditional Chinese medicine application composition provides a better pure traditional Chinese medicine preparation for patients with endocrine insomnia and anxiety. The clinical curative effect is obvious.

The invention relates to the field of traditional Chinese medicines, and discloses an application formula for warming channels and relieving pain and a preparation method thereof. The application formula comprises the following raw materials: fennel, caulis spatholobi, trogopterus dung, pollen typhae, angelica sinensis, asarum, radix paeoniae alba, turmeric, corydalis tuber, rhizoma drynariae, fructus psoraleae and pericarpium zanthoxyli. During preparation, all the raw materials are ground into 300-mesh medicine powder, so that the medicine components are not damaged, and meanwhile, the effective components of the medicine can fully play a role. Vaseline and folium artemisiae argyi and ginger oil are prepared into a mixed oil agent according to the mass ratio of 3: 1, then the mixed oil agent and medicine powder are mixed according to the mass ratio of 1: 2 to be prepared into paste, and the paste is completely covered with gauze after being applied and filled with a blank breathable adhesive patch, so that it is guaranteed that the medicine is fixed and does not seep out. According to the present invention, the pain relieving effect is mainly achieved by warming channels, expelling cold, promoting blood circulation and dredging collaterals, the root causes are treated by warming channels, the pain is relieved by dredging collaterals, and the symptoms are treated by dredging collaterals, such that the clinical application results show that the significant treatment effect on various pains such as waist, knee and leg pains, shoulder and neck pains, dysmenorrhea and the like is provided.

This invention discloses a topical Chinese medicine preparation for treating erosive tinea pedis and its preparation method, belonging to the technical field of topical Chinese medicine preparations. The preparation consists of 15-25 parts clove, 10-20 parts alum, 20-30 parts Polygonum cuspidatum, and 10-18 parts Psoralea corylifolia, and is prepared into a spray using a 45% low-alcohol countercurrent extraction process. This invention achieves synergistic effects through a three-stage targeting mechanism: eugenol inhibits fungal CYP51A1 enzyme, blocking ergosterol synthesis (targeted enrichment rate 62.1%), resveratrol inhibits the NF-κB pathway, reducing inflammatory response, and psoralen activates the PI3K / AKT pathway, promoting epidermal repair (repair rate 69.2%). The alcohol concentration of the preparation is reduced to 45%, eliminating irritation to broken wounds. A single application takes only 1 minute, and a 7-day treatment course has a clinical efficacy rate of 84.7%, saving 320 yuan per person compared to traditional methods. This invention overcomes the shortcomings of existing drugs for treating erosive tinea pedis, such as strong irritation, cumbersome operation, and limited efficacy, and fills the gap in the category of specialized preparations, with significant social benefits and market prospects.

The invention provides a traditional Chinese medicine compound composition taking glossy privet fruit as a monarch drug as well as a preparation method and application of the traditional Chinese medicine compound composition. The traditional Chinese medicine compound composition comprises the following raw materials in parts by weight: 15-35 parts of glossy privet fruit, 20-40 parts of oyster, 10-25 parts of curcuma zedoary, 5-25 parts of wine-treated rhubarb, 5-25 parts of roasted rhizoma atractylodis macrocephalae and 20-40 parts of oldenlandia diffusa. The traditional Chinese medicine compound composition is obvious in tumor treatment effect, can nourish liver and kidney, strengthen healthy energy to assist in removing food retention, promote qi circulation, break blood, remove food retention and relieve pain, has the effects of nourishing yin, softening hard mass, activating blood and detoxifying, and has the characteristics of high practical operability, high compliance, high tumor inhibition rate and low adverse reaction.

The application belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine compound preparation for treating anal eczema as well as a preparation method and application thereof. The traditional Chinese medicine compound preparation is prepared from the following raw medicinal materials in parts by weight: 35-45 parts of Sophora flavescens, 35-45 parts of Cnidium monnieri, 18-22 parts of Semen Astragali Complanati, 18-22 parts of Cortex Dictamni, 18-22 parts of Scutellaria baicalensis, 118-22 parts of Phellodendri, 10-14 parts of Chuanxiong Rhizoma, 16-20 parts of Angelica sinensis, 10-14 parts of Radix Paeoniae Alba, 16-20 parts of Saposhnikovia divaricata, and 10-14 parts of Gleditsia sinensis. The application provides a traditional Chinese medicine compound preparation and a Chinese medicine treatment method for treating acute and chronic anal eczema caused by 'damp-heat invasion'. The traditional Chinese medicine compound preparation can not only significantly relieve the perianal pruritus and exudation of the patients with anal eczema, but also effectively reduce the skin lesion area and improve the skin lesion state, and the clinical curative effect is obvious. In addition, the raw materials of the traditional Chinese medicine compound preparation are widely sourced and low in price, the pure traditional Chinese medicine raw materials are used for processing, and the preparation process is simple.

This invention provides a traditional Chinese medicine composition for clearing the lungs and relieving asthma, its granules, and their applications, relating to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition for clearing the lungs and relieving asthma of this invention is prepared from the following raw materials in the indicated weight proportions: Ephedra 8-12g, Earthworm 8-12g, Bitter Apricot Kernel 8-12g, Mulberry Bark 8-12g, Coltsfoot Flower 13-18g, Stemona 13-18g, Platycodon Root 8-12g, Prepared Pinellia Rhizome 8-12g, Tangerine Peel 8-12g, Ginkgo Root 8-12g, Scutellaria Root 13-18g, Perilla Seed 13-18g, Trichosanthes Peel 25-35g, Peucedanum Root 8-12g, and Belamcanda Rhizome 8-12g. The traditional Chinese medicine formula provided by this invention has good clinical efficacy in treating chronic obstructive pulmonary disease, with high clinical control and efficacy rates, and a high overall effective rate.

The present invention relates to a technique for preventing scar hyperplasia after canthalectomy, and more particularly to a device for preventing and treating scars after canthalectomy. The device for preventing and treating scars after canthalectomy of the present invention comprises a bracket, wherein the bracket has two extension parts extending to the two inner canthi of the patient respectively, and the ends of the extension parts are respectively provided with anastomotic parts for wrapping and pressurizing the inner canthus. Advantages: simple and reasonable structural design, easy operation and use, can effectively prevent or treat scar hyperplasia after canthalectomy, safe and comfortable to use, and good clinical effect.

Provided in the present invention are an anti-human thymic stromal lymphopoietin (TSLP) monoclonal antibody and the use thereof. The monoclonal antibody has high affinity for human TSLP, has a neutralizing activity, and can be used for preventing or treating TSLP-mediated diseases.

The invention discloses a pharmaceutical composition for reinforcing the kidney and producing sperms as well as a preparation and application of the pharmaceutical composition for reinforcing the kidney and producing sperms. The traditional Chinese medicine composition is prepared from prepared rehmannia root, deer-horn glue, salted flatstem milkvetch seed, radix scrophulariae, radix rehmanniae recen, codonopsis pilosula, astragalus membranaceus, roasted astragalus membranaceus, fructus lycii, salted semen cuscutae, raspberry, wine-processed teasel root, salted eucommia ulmoides, roasted rhizoma polygonati, roasted rhizoma atractylodis macrocephalae, pericarpium citri reticulatae, poria cocos, longan aril, bran-fried Chinese yam, Chinese date, salted semen plantaginis, leonurus, salvia miltiorrhiza, centipede, ligusticum wallichii, caulis spatholobi, radix bupleuri, vinegar-processed schisandra chinensis and calcined dragon bone. The pharmaceutical composition for reinforcing kidney and producing sperm is added with pharmaceutically acceptable auxiliary materials to prepare a preparation. The pharmaceutical composition for reinforcing kidney and producing sperm and the preparation thereof can be used for preparing medicines for invigorating spleen and replenishing qi, promoting qi to activate blood, and tonifying kidney and producing sperm.

The invention provides a valve leaflet repairing device, system and method. The valve leaflet repairing device comprises a fixing part; the first ends of the first clamping arm and the second clamping arm are respectively arranged on the fixing piece, and the second ends of the first clamping arm and the second clamping arm are oppositely arranged in an opening and closing manner; the implanted valve leaflet is partially arranged on the first clamping arm and extends to the side, away from the first clamping arm, of the fixing piece; the first clamp arm and the second clamp arm are configured to clamp the native valve leaflet such that the implanted valve leaflet becomes an extension of the native valve leaflet. According to the method, the original valve leaflet can be equivalently lengthened, the reflux problem is solved, the valve opening cannot be shrunk, and valve leaflet replacement can be easily carried out subsequently.

The invention belongs to the technical field of medicines, and particularly relates to application of kaifeng essence to preparation of a medicine for treating premature ovarian insufficiency. The kaifeng essence has high total effective rate for adjuvant therapy of premature ovarian insufficiency and obvious clinical curative effect, and is a potential effective therapeutic drug.

The invention discloses a kidney-tonifying and spleen-tonifying traditional Chinese medicine composition as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 10 to 40 parts of roasted turtle shell, 10 to 30 parts of herba taxilli, 10 to 20 parts of cortex eucommiae, 10 to 30 parts of semen cuscutae, 10 to 30 parts of herba cistanche, 10 to 30 parts of radix codonopsis, 10 to 30 parts of poria cocos, 10 to 30 parts of rhizoma polygoni cuspidati and 10 to 30 parts of rhizoma chuanxiong. The traditional Chinese medicine composition disclosed by the invention has the effects of tonifying kidney and spleen, dissipating blood stasis and relieving pain, and softening hardness to dissipate stagnation, is a proved recipe for clinical application for many years, is stable in curative effect, few in adverse reaction and good in healing, and provides an effective traditional Chinese medicine preparation for treating stable angina pectoris. During preparation of the traditional Chinese medicine composition, monarch drugs are pulverized and used as medicines, other medicines are extracted and concentrated, medicinal components are fully reserved, and the traditional Chinese medicine composition is simple in process, high in universality and suitable for large-scale production.

The invention discloses a traditional Chinese medicine composition for treating idiopathic oligospermia, which relates to the technical field of Chinese herbal medicines, and is characterized in that the composition is a medicament prepared from the following raw material medicines by weight: 40-50 g of pilose antler, 40-50 g of hippocampus, 50-70 g of ginseng, 20-40 g of cistanche, 10-30 g of epimedium, 10-30 g of schisandra chinensis, 30-50 g of semen cuscutae, 20-40 g of medlar, 5-15 g of fructus psoraleae, 10-20 g of pericarpium citri reticulatae and 5-15 g of cuttlebone. The traditional Chinese medicine composition for treating idiopathic oligospermia and asthenospermia forms a more effective treatment method, and has great significance in improving sperm quality of patients with idiopathic oligospermia and asthenospermia, improving fertility of the patients, improving sexual dysfunction and promoting healthy development of social population.

The utility model discloses a novel micro catheter, and belongs to the field of medical instruments. Comprising a microcatheter body, the microcatheter body comprises an inner catheter layer, a middle layer and an outer sleeve layer, the middle layer is connected with the inner catheter layer and the outer sleeve layer, the microcatheter is characterized in that the outer sleeve layer is composed of a plurality of splicing sections, and the adjacent splicing sections of the splicing sections are spliced in a staggered mode. The outer sleeve layer is provided with the multiple splicing sections and the middle layer, the multiple splicing sections can be made of different materials according to needs, the size of the catheter is not changed, and the adhesion, smoothness, flexibility, torsion control, fracture resistance, tensile resistance and ellipticity resistance of the multi-layer structure such as the inner catheter layer, the middle layer and the outer sleeve layer can be remarkably improved; and an excellent clinical use effect is achieved.

The invention provides a medicine composition of a thin gauze for treating burn wounds and capable of detoxifying and astringing, a preparation and a preparation method, and relates to the technical field of traditional Chinese medicine, and the medicine composition is prepared from the following components in specific parts by weight: rheum officinale, carbonized sanguisorba root, gallnut, red halloysite, calamine and borneol. The preparation method comprises the following steps: grinding the medicines into fine powder, heating and dissolving the beewax in the oil, filtering out impurities, adding the medicine powder after the oil is slightly cooled, continuously stirring uniformly, and cooling to obtain the ointment. And after disinfection, the medicine is used clinically. The traditional Chinese medicine compound disclosed by the invention can effectively clear away heat and toxic materials, astringe and promote tissue regeneration, is supported by a solid classical theory of traditional Chinese medicine, is reasonable in component proportion, excellent in medicine compatibility, low in cost and easy in quality control, and is proved by animal and clinical experiments to be capable of resisting infection and exudation, exact in curative effect and free of toxic and side effects; the traditional Chinese medicine composition can be applied to preparation of the traditional Chinese medicine composition for shallow and deep I-degree burn wounds.

The invention belongs to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine formula for treating qi and blood deficiency type alopecia areata through acupuncture and moxibustion comprehensive therapy and application. According to the formula, fructus psoraleae and radix polygoni multiflori are used as monarch drugs and mainly used for tonifying liver and kidney and providing fundamental treatment for qi and blood deficiency type alopecia areata; the safflower, the peach kernel, the ligusticum chuanxiong hort, the salvia miltiorrhiza and the angelica sinensis are used as ministerial drugs and have the main effects of activating and nourishing blood, promoting blood circulation and improving nutrition supply of scalp; chinese arborvitae twig, divaricate saposhnikovia root and tribulus terrestris are used as adjuvant drugs, have the effects of dispelling wind, promoting hair growth and arresting itching, and are beneficial to relieving uncomfortable symptoms of scalp and promoting hair follicle health; the ginger has the effect of warming meridians and collaterals and assists other medicines in exerting medicine properties. The medicinal materials in the formula are soaked in 75% alcohol to extract effective components, and the liniment is prepared. In clinical treatment, plum-blossom needle stabbing and mild moxibustion are combined, and medicine introduction and absorption are improved. Research shows that the formula can remarkably improve the alopecia areata symptom and improve the treatment efficiency and patient compliance, and has high clinical application value.

The invention provides a moisture absorption paper tip set for an apical operation. Comprising a first moisture absorption paper tip set suitable for conventional tooth positions, a second moisture absorption paper tip set suitable for tooth positions with fused root canals and thick root canals and a first maxillary premolar with isthmus. The moisture absorption paper tip group III is suitable for upper jaw first molars with isthmus on two mesial cheek roots; the moisture absorption paper tip group IV is suitable for lower jaw second molars with C-shaped root canals; the first moisture absorption paper tip set, the second moisture absorption paper tip set, the third moisture absorption paper tip set and the fourth moisture absorption paper tip set each comprise a clamping part and a water absorption part, and the water absorption part of the first moisture absorption paper tip set is in a cylinder shape with the diameter being 0.6 mm. The water absorption part of the moisture absorption paper tip group II is a cylinder with the diameter of 0.8 mm; the water absorption part of the moisture absorption paper tip group III is a column with a barbell-shaped section; the width of the barbell-shaped section is 1.7 mm, the thicknesses of the two ends are 0.6 mm, and the thickness of the middle is 0.5 mm; a water absorption part of the moisture absorption paper tip group IV is a column with a fusiform section; the width of the fusiform section is 1.7 mm, the thickness of the middle of the fusiform section is 0.6 mm, and the two ends of the fusiform section are sharp.

The invention relates to the technical field of veterinary drugs, and provides acetylcysteine soluble powder and application thereof. Research finds that acetylcysteine can improve the sensitivity of chicken mycoplasma to antibiotics, so that the acetylcysteine soluble powder is provided and comprises the following components: 10%-50% of acetylcysteine, 1%-10% of a metal complexing agent, 2%-12% of a cosolvent, 0.001%-0.01% of an antioxidant, 0.1%-2% of a flavoring agent, 0.001%-0.1% of a preservative and the balance of a filler. The acetylcysteine soluble powder not only can significantly improve the treatment effect of antibiotics on chicken mycoplasmosis, but also can reduce the occurrence of drug resistance of pathogenic bacteria.

The invention provides an internal-organ-warming traditional Chinese medicine application composition capable of bidirectionally regulating gastrointestinal motility and a preparation method, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 10-15 parts of rhizoma zingiberis, 10-15 parts of cortex cinnamomi, 20-25 parts of folium artemisiae argyi, 10-15 parts of fennel, 6-9 parts of fructus evodiae, 10-15 parts of radix aucklandiae, 10-20 parts of flos carthami and 10-15 parts of rhizoma atractylodis. The bowel-warming traditional Chinese medicine application composition capable of bidirectionally regulating gastrointestinal motility provides a new choice for gastrointestinal motility weakening or hyperfunction, the preparation method provides a better pure traditional Chinese medicine preparation for patients with gastrointestinal motility weakening or hyperfunction, and the clinical curative effect of the bowel-warming traditional Chinese medicine application composition is remarkable.

The invention discloses a traditional Chinese medicine composition, and belongs to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 15 to 24 parts of bupleurum chinense, 9 to 15 parts of radix scutellariae slices, 20 to 30 parts of parched white paeony root, 20 to 30 parts of bran-fried immature bitter orange, 9 to 15 parts of ginger processed pinellia, 15 to 20 parts of ginger processed officinal magnolia bark, 10 to 20 parts of fresh ginger, 6 to 10 parts of mirabilite, 10 to 15 parts of Chinese date, 15 to 20 parts of polyporus umbellatus, 15 to 30 parts of rheum officinale, 20 to 30 parts of herba lycopi, 15 to 20 parts of semen lepidii, 10 to 20 parts of semen armeniacae amarae, 10 to 15 parts of earthworm, 20 to 30 parts of rhizoma alismatis and 0.5 to 1 part of euphorbia kansui powder. The traditional Chinese medicine composition provided by the invention has the effects of relaxing bowels, removing heat, resolving Shaoyang, relieving asthma, dispersing blood stasis and dredging collaterals, can effectively relieve clinical symptoms such as abdominal distension, abdominal pain, gastrointestinal dysfunction and the like of AP patients, reduces serum inflammation indexes and improves pancreatic functions.

The invention belongs to the technical field of traditional Chinese medicines, and relates to a traditional Chinese medicine composition and a preparation method and application thereof, in particular to a traditional Chinese medicine composition and a preparation method thereof and application in preparation of medicines for treating diabetes mellitus, especially diabetes mellitus complicated with metabolism-related fatty liver diseases. The traditional Chinese medicine composition is prepared from the following raw materials: 920 to 1200 parts of fructus crataegi, 240 to 400 parts of radix bupleuri, 580 to 700 parts of radix salviae miltiorrhizae, 240 to 400 parts of radix curcumae, 352 to 500 parts of semen cassiae, 240 to 400 parts of rhizoma pinellinae praeparata, 352 to 500 parts of rhizoma alismatis and 240 to 400 parts of pericarpium citri reticulatae. Furthermore, the mass ratio of hawthorn to radix bupleuri to salvia miltiorrhiza to radix curcumae to semen cassiae to rhizoma pinellinae praeparata to rhizoma alismatis to pericarpium citri reticulatae is (3-4): (1-2): (2-3): (1-2): (1-3): (1-2): (1-3): (1-2). The composition is prepared by the following steps: respectively removing impurities and dust from hawthorn, radix bupleuri, salvia miltiorrhiza, radix curcumae, semen cassiae, rhizoma pinellinae praeparata, rhizoma alismatis and pericarpium citri reticulatae, drying, respectively grinding, and mixing in proportion. The composition disclosed by the invention not only has an obvious effect of reducing blood sugar, but also has an effect of reducing blood fat, and is better for diabetes mellitus complicated with fatty liver.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition and a preparation method and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine components in parts by weight: 10-20 parts of wine-processed scutellaria baicalensis, 20-30 parts of radix sophorae flavescentis, 15-20 parts of raw rhubarb, 6-12 parts of angelica sinensis, 8-12 parts of cinnamon, 6-12 parts of elecampane, 15-20 parts of mirabilite, 3-5 parts of wine-processed coptis chinensis and 20-30 parts of golden cypress. According to the traditional Chinese medicine composition prepared by the invention, the red, swollen and pain caused by acute attack of anal diseases are relieved according to the drug compatibility principle of monarch, minister, assistant and guide; and the occurrence of complications such as anal diseases, postoperative pain, edema, anal pendant expansion and the like is obviously reduced.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating endometrial polyp as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from rhizoma smilacis glabrae, platycodon grandiflorum, honeysuckle, salvia miltiorrhiza, corydalis tuber, rhizoma atractylodis, selfheal, szechwan chinaberry fruit, Chinese yam, radix scrophulariae, endothelium The traditional Chinese medicine composition disclosed by the invention has the effects of tonifying spleen and qi, and removing blood stasis and eliminating diseases. A research result shows that the traditional Chinese medicine composition has a remarkable clinical curative effect on spleen deficiency and blood stasis type endometrial polyp, and can improve the menstrual condition of a patient, reduce the traditional Chinese medicine syndrome integral, reduce relapse and improve the detection indexes of the patient including serum VEGF and IL-6.