294 results about "Curcuma zedoaria" patented technology

The invention discloses a traditional Chinese medicine composition for treating skin diseases and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 6-12 parts of radix notoginseng, 8-15 parts of radix salviae miltiorrhizae, 10-20 parts of rhizoma chuanxiong, 8-15 parts of rhizoma curcumae longae, 15-35 parts of radix angelicae sinensis, 3-8 parts of sandalwood, 3-8 parts of fructus aurantii immaturus, 40-60 parts of ramulus cinnamomi, 8-15 parts of rhizoma corydalis, 8-15 parts of rhizoma curcumae, 2-5 parts of flos carthami, 5-12 parts of radix puerariae, 8-15 parts of radix rehmanniae, 3-8 parts of pericarpium citri reticulatae and 8-15 parts of spica prunellae. The traditional Chinese medicine composition is prepared from 3-8 parts of radix trichosanthis, 15-35 parts of tribulus terrestris, 15-35 parts of cicada slough, 5-12 parts of stiff silkworm and 8-15 parts of rhizoma drynariae. According to a multi-target collaborative mechanism, network pharmacology proves that 12 pathological pathways such as IL-17A and the like can be regulated and controlled, and the TNF-alpha inhibition rate is 89% and the barrier repair speed is increased by 2.3 times through key component combination. According to a transdermal synergistic technology, the specific surface area of the medicine reaches 8.5 m < 2 > / g through superfine grinding, a Franz test shows that the penetration amount of tanshinone is increased by 3.7 times, and the onset time is shortened to 8.3 minutes. Dual scar regulation and control: the thickness of scars in 12 weeks is reduced by half through TGF-beta3 up-regulation and alpha-SMA inhibition, and the collagen order degree is improved by 3.2 times.

The invention discloses a traditional Chinese medicine composition for treating liver cirrhosis and a preparation method thereof, and belongs to the technical field of anti-liver cirrhosis traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 10g of polyporus umbellatus, 10g of herba artemisiae scopariae, 10g of radix bupleuri, 10g of charred rheum officinale, 10g of rhizoma coptidis, 10g of charred radix scutellariae, 10g of fructus gardeniae, 15g of herba hyperici japonici, 10g of radix curcumae, 10g of rhizoma alismatis, 10g of radix paeoniae rubra, 10g of radix salviae miltiorrhizae, 10g of cortex magnoliae officinalis, 10g of fructus aurantii, 10g of rhizoma cyperi, 10g of rhizoma sparganii, 10g of rhizoma curcumae, 20g of plantain herb, 10g of turtle shell, 10g of pericarpium arecae, 25g of oven earth and 2g of charred colla corii asini. By providing the traditional Chinese medicine composition formula for treating the liver cirrhosis, the effective rate and the cure rate of the medicine for treating the liver cirrhosis are improved.

The invention belongs to the technical field of biological medicines, and particularly relates to a traditional Chinese medicine composition for treating metabolism-related fatty liver diseases and a preparation method thereof. The technical problem to be solved by the invention is to provide a new choice for treating metabolism-related fatty liver diseases. According to the technical scheme, the traditional Chinese medicine composition for treating the metabolism-related fatty liver disease is prepared from the following components: radix paeoniae rubra, cyrtomium fortunei, curcuma zedoary, sculellaria barbata, herba epimedii, fingered citron, semen cassiae and herba artemisiae scopariae. The invention is mainly used for providing a new choice for treating the metabolism-related fatty liver disease, and has a wide application prospect.

The invention discloses a preparation method of granules for treating breast and thyroid nodules and canceration, which comprises the following steps: S1, raw material preparation: preparing 199g of codonopsis pilosula, 332g of astragalus membranaceus, 149g of glossy privet fruit, 100g of herba epimedii, 166g of selfheal, 100g of uniflower swisscentaury root, 100g of rhizoma pinellinae praeparata, 100g of curcuma zedoary, 199g of salvia chinensis, 332g of selaginella doederleinii hieron, 100g of curcuma aromatica and 149g of cortex albiziae according to a mass ratio; s2, adding water to decoct the twelve medicines twice, adding 8 times by mass of water for the first time, extracting for 2.0 hours, and filtering; s3, adding 6 times by mass of water for the second time, extracting for 1.5 hours, filtering, and combining filtrates; s4, concentrating under reduced pressure to obtain clear paste with the relative density of about 1.05-1.10 (60 DEG C); and S5, performing vacuum drying, crushing into fine powder, adding dextrin and 10g of stevioside, uniformly mixing, granulating with 75% by volume of ethanol, drying, preparing into 1000g, and packaging, thereby obtaining the product.

The invention discloses a Chinese medicine preparation for treating pulmonary nodules and a preparation method thereof, and relates to the technical field of medicines for treating respiratory diseases. Compared with the prior art, the Chinese medicine preparation for treating pulmonary nodules prepared by the invention is treated from five aspects, including tonifying the lung and replenishing qi, resolving phlegm and eliminating phlegm, softening and dispersing nodules, clearing away heat and detoxifying, and eliminating carbuncle and dispersing nodules, by combining selected medicinal materials of Codonopsis pilosula, Astragalus membranaceus, Chinese yam, Schisandra chinensis, Rehmannia glutinosa, Morus alba, Salvia miltiorrhiza, Curcuma zedoaria, Concha oyster, Scrophularia ningpoensis, Rhizoma Anemarrhenae, Scutellaria barbata, and Beehive. It is aimed at treating both the symptoms and the root cause of pulmonary nodules caused by lung deficiency, phlegm, dampness and blood stasis coagulation in the lungs, and is convenient to take, and can effectively control and reduce pulmonary nodules. The preparation of the Chinese medicine preparation of the invention optimizes the heat transfer and mass transfer in the decoction process by physically adding a carrier during the decoction process, changes the osmotic pressure difference at the interface of the medicine liquid, etc., accelerates the dissolution and diffusion of the effective ingredients, is easier to extract and prepare, has a shorter decoction time, and is more efficient.

The invention discloses a traditional Chinese medicine composition for treating pulmonary nodule as well as a preparation, a preparation method and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 30-45 parts of oyster, 15-30 parts of selfheal, 10-15 parts of radix scrophulariae, 10-15 parts of thunberg fritillary bulb, 10-15 parts of dandelion, 10-15 parts of curcuma zedoary and 5-10 parts of pseudobulbus cremastrae seu pleiones. The traditional Chinese medicine composition for treating the phlegm-heat stagnation type pulmonary nodules has the effects of clearing heat, eliminating phlegm, removing blood stasis and eliminating stagnation, is obvious in clinical effect, has a reliable empirical basis, and is expected in economic and social benefits.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating lung cancer and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: lily, radix ophiopogonis, thunberg fritillary bulb, astragalus membranaceus, curcuma zedoary, lychee seed, poria cocos, radix scrophulariae, rhizoma anemarrhenae and loofah sponge. The traditional Chinese medicine composition has the effects of tonifying qi and yin, reducing phlegm and resolving masses, and is particularly suitable for treating a patient suffering from qi-yin deficiency and blood stasis type small cell lung cancer. The traditional Chinese medicine composition disclosed by the invention has the effects of reducing tumor cell proliferation, regulating tumor immunity, reducing toxicity and enhancing efficacy, and can also enhance the immunity of a patient, prolong the lifetime of the patient and improve the living quality of the patient.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating constipation and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from betel nut, szechwan chinaberry fruit, bighead atractylodes rhizome, bunge cherry seed, vinegar-processed curcuma zedoary, immature bitter orange, officinal magnolia bark, coix seed and Chinese angelica. The traditional Chinese medicine composition disclosed by the invention has the effects of promoting qi circulation, removing stagnation, tonifying spleen, clearing damp, relaxing bowel, nourishing blood and promoting blood circulation, is mainly used for treating qi stagnation type, spleen deficiency type or mixed type constipation, and is particularly suitable for functional constipation, senile constipation or postpartum constipation with the syndromes. Besides, the traditional Chinese medicine composition is deeply optimized by utilizing a modern preparation process on the basis of a traditional Chinese medicine formula, the preparation method is simple, and the traditional Chinese medicine composition can be prepared into various dosage forms such as granules, tablets, oral liquid or capsules.

The invention discloses a traditional Chinese medicine compound exosome for treating ovarian cancer and a preparation method and application thereof. The preparation method of the traditional Chinese medicine compound exosome comprises the following steps: (1) soaking the raw material medicines in the traditional Chinese medicine compound in deionized water, boiling with big fire, and decocting for 35-45 minutes; then adjusting to slow fire, and continuously decocting for 30-35 minutes to obtain the traditional Chinese medicine compound water decoction. (2) preparing the traditional Chinese medicine compound exosome from the traditional Chinese medicine compound water decoction by an ultracentrifugation method; wherein the traditional Chinese medicine compound comprises the following raw material medicines: astragalus membranaceus, bighead atractylodes rhizome, cinnamon, curcuma zedoary, fructus lycii, seaweed, pericarpium citri reticulatae viride, lindera aggregata, turtle shell, oldenlandia diffusa, scorpio, artemisia apiacea, arisaema cum bile, edible tulip and radix ranunculi ternati. The prepared traditional Chinese medicine compound exosome can be used for treating ovarian cancer, and the curative effect of the exosome is superior to that of a traditional traditional Chinese medicine compound administration mode.

The invention discloses a traditional Chinese medicine composition for treating atherosclerosis and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20 parts of vinegar turtle shell, 5-15 parts of immature bitter orange, 5-15 parts of vinegar rhizoma sparganii, 2-10 parts of arisaema cum bile, 5-15 parts of vinegar curcuma zedoary, 20-40 parts of raw oyster, 10-20 parts of radix fici simplicissimae and 5-15 parts of semen brassicae. The weight ratio of the vinegar turtle to the raw oyster to the radix fici simplicissimae is (1: 1)-(4: 1); the weight ratio of the immature bitter orange to the arisaema cum bile to the semen brassicae is (5: 1)-(4: 5). Compared with the prior art, the pharmaceutical composition has a better treatment effect on atherosclerosis, can effectively reduce the drug administration dosage, and has the advantages of low cost and better safety.

The invention discloses a formula for reducing phlegm and resolving masses, and a preparation method and application of freeze-dried powder of the formula for reducing phlegm and resolving masses, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition inhibits triple negative breast cancer adhesion-metastasis by regulating an FAK / SRC pathway, and comprises the following components by weight: 10-20 g of poria cocos, 10-20 g of rhizoma bolbostemmae, 10-20 g of radix trichosanthis, 5-12 g of curcuma zedoary, 10-20 g of selfheal, 10-20 g of oyster (smashed and decocted first), and 5-12 g of uniflower swisscentaury root. In-vitro experiments show that HTSJF can inhibit TNBC cell invasion, migration and adhesion (P is less than 0.01) in a dose-dependent manner, and along with reduction of the phosphorylation level of an FAK / SRC pathway, it is prompted that HTSJF inhibits TNBC transfer by regulating the pathway. In-vivo experiments prove that the HTSJF can obviously inhibit the reduction of TNBC pulmonary metastasis focus (P is less than 0.05) and recover part of normal pulmonary alveolar structures, and the inhibition effect of the HTSJF on TNBC pulmonary metastasis is further proved.

The invention relates to a traditional Chinese medicine composition for treating infantile malnutrition, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 7 to 15g of striga asiatica, 8 to 16g of quince, 8 to 15g of raw rhubarb, 9 to 17g of cooked rhubarb, 9 to 16g of vernonia graveolens, 7 to 13g of black semen pharbitidis, 6 to 15g of white semen pharbitidis, 6 to 15g of semen nigellae, 15 to 20g of rhizoma sparganii, 16 to 19g of curcuma zedoary, 9 to 17g of fructus amomi and 10 to 19g of pedicularis muscicola. The traditional Chinese medicine formula disclosed by the invention has the effects of removing food retention, relieving dyspepsia, strengthening the spleen and stomach and expelling parasites, and is a traditional Chinese medicine formula capable of treating the infantile malnutrition, enhancing the immunity of the organism, recuperating the physical function of children and improving the physical quality of the children. The preparation method of the powder prepared from the traditional Chinese medicine formula is inherited for a long time, the compatibility is flexible, the taking modes are various, and the curative effect is remarkable and quick.

The invention discloses a traditional Chinese medicine composition for treating esophageal cancer. The traditional Chinese medicine composition is prepared from, by weight, 180-210 g of prepared rehmannia roots, 120-150 g of radix clematidis, 100-120 g of rhizoma atractylodis macrocephalae, 120-150 g of fructus lycii, 120-150 g of semen cuscutae, 100-120 g of rhizoma alismatis, 100-120 g of rhizoma dioscoreae, 40-60 g of taxus chinensis, 100-120 g of codonopsis pilosula, 20-40 g of scorpions, 40-60 g of curcuma zedoary, 60-80 g of peach kernels, 120-150 g of salvia chinensis, 120-150 g of rabdosia rubescens, 90-120 g of Chinese dates, 100-120 g of camptotheca acuminate, 30-50 g of ground beetles, 60-80 g of pseudo-ginseng The composition has the effect of treating both symptoms and root causes in the aspect of treating esophageal cancer, can control tumors, improve the living quality of patients and prolong survival, and is small in side effect.

The invention discloses a Chinese herbal medicine composition, a preparation method and application of the Chinese herbal medicine composition in freckle-removing and whitening products. The Chinese herbal medicine composition comprises the following raw materials in parts by weight: 45-60 parts of lonicerae flos / dogwood leavening, 20-35 parts of bletilla striata extract and 20-35 parts of curcuma zedoary extract. Wherein the lonicerae flos / dogwood leavening is obtained by activating bifidobacteria, inoculating the bifidobacteria into a seed culture medium, culturing to obtain a seed solution, then transferring the seed solution into a fermentation culture medium, culturing to obtain a fermentation solution, and finally filtering and freeze-drying the fermentation solution; wherein the seed culture medium contains a dogwood extract, and the fermentation culture medium contains a lonicerae flos extract and a dogwood extract. All the components in the Chinese herbal medicine composition have a synergistic effect, and the Chinese herbal medicine composition has the remarkable effects of resisting oxidation, inhibiting tyrosine, repairing ultraviolet aging skin and the like.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine electuary for intestinal injury caused by radiotherapy and chemotherapy and a preparation method of the traditional Chinese medicine electuary. According to the composition principle of monarch, minister, assistant and guide of a traditional Chinese medicine prescription, the traditional Chinese medicine electuary is prepared by taking radix astragali preparata as a monarch drug, taking radix codonopsis and rhizoma polygonati as minister drugs, and taking poria cocos, bran-fried rhizoma atractylodis macrocephalae, hairyvein agrimony, Chinese pulsatilla root, rhizoma bletillae and pinellia ternate as assistant drugs, and taking pericarpium citri reticulatae, vinegar-processed curcuma zedoary, pseudo-ginseng and musk as assistant drugs through scientific compatibility and a preparation process. The intestinal function can be adjusted, and the intestinal injury symptom caused by radiotherapy and chemotherapy is improved.

The invention belongs to the field of medicines, and relates to a traditional Chinese medicine composition for dispelling the effects of alcohol and relieving alcoholic liver injury and application thereof. The pharmaceutical composition is prepared from the following raw materials: curcuma zedoary, fructus amomi, rhizoma alismatis, rhizoma atractylodis macrocephalae and radix angelicae.

The invention provides Xinmaikang tablets and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The Xinmaikang tablet comprises medicinal components and auxiliary materials, the medicine components comprise turtle shells, rhizoma sparganii, curcuma zedoary, immature bitter oranges, prepared arisaema cum bile and dendrobe, and the auxiliary materials comprise a disintegrating agent, a filling agent and a lubricating agent. On the basis of the patent CN109700972A, auxiliary materials are selected, so that the prepared Xinmaikang tablet has better stability and brittleness, and the disintegration efficiency and the dissolution rate of the tablet both meet the requirements.

The invention provides a method for increasing the content of geranone and furandiene in zedoary turmeric oil, which comprises the following steps: activating secondary metabolism through moderate drought, low temperature or salt stress in a key growth period of zedoary turmeric, and promoting sesquiterpene accumulation; then, phosphorus-potassium fertilizer and zinc-boron trace elements are additionally applied, nitrogen fertilizer is reduced, and the component proportion is optimized; the preparation method comprises the following steps: washing, drying and crushing the rhizome of curcuma zedoary, adding water to infiltrate, extracting crude oil by water vapor, performing reduced pressure distillation and molecular distillation purification, finally filling nitrogen and sealing, and refrigerating at 2-4 DEG C and storing in a dark place. According to the method, the content and extraction rate of target components can be remarkably increased, purity is guaranteed, thermosensitive components are protected, pollution is reduced, and the storage period is prolonged.

The invention relates to a Chinese medicine composition, and discloses a medicine composition for treating chronic atrophic gastritis, a preparation method thereof and a use thereof. The medicine composition is prepared from effective ingredients and pharmaceutically acceptable auxiliary materials, wherein the effective ingredients are prepared from raw materials in the following weight ratio: 4-8g of red ginseng, 12-18g of white atractylodes, 4-8g of notoginseng, 4-6g of angelica, 8-12g of curcuma, 12-18g of coix seed, 12-18g of fritillaria thunbergii, 8-12g of dendrobium, 12-18g of falanghai, and 8-12g of salacia. Red ginseng and notoginseng are extracted by ethanol refluxing to obtain red ginseng and notoginseng extracts; red ginseng, notoginseng residues and the remaining eight raw materials are boiled and extracted with water, and the filtrate is concentrated and then added with the red ginseng and notoginseng extracts to prepare the preparation. This combination warms the spleen and replenishes qi, removes dampness and resolves blood stasis. It is used for chronic atrophic gastritis caused by spleen and stomach yang deficiency, internal obstruction of dampness and blood stasis, or accompanied by intestinal metaplasia and intraepithelial neoplasia. Symptoms include fullness in the epigastric region, noisy or dull pain in the stomach, decreased appetite, etc. It has a significant therapeutic effect on spleen and stomach yang deficiency, internal obstruction of dampness and blood stasis, etc.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating pleural effusion and peritoneal effusion and a preparation method thereof.The traditional Chinese medicine preparation is prepared from, by weight, 10-50 parts of traditional Chinese medicine extract, 30-70 parts of filler, 5-20 parts of enteric coating material, 5-15 parts of HPMC, 0.5-2 parts of triethyl citrate and 0.25-1.5 parts of magnesium stearate; poria cocos, polyporus umbellatus, rhizoma alismatis, astragalus membranaceus, curcuma zedoary, cassia twig, oldenlandia diffusa, sculellaria barbata, semen coicis and traditional Chinese medicine extracts are used as cores, the stability of volatile drugs is improved through an inclusion technology, and the volatile drugs are entrapped in a pH intelligent response type enteric coating material composed of aromatic ring-containing vinyl monomers, ethyl acrylate, DMAEMA and MAA. The traditional Chinese medicine preparation has the synergistic effect of efficiently inducing diuresis, activating blood circulation and eliminating tumors and enteric-coated long-acting directional delivery, and is suitable for patients with pleural effusion and peritoneal effusion, especially malignant effusion.

The present application relates to a kind of anti-non-small cell lung cancer for strengthening healthy qi and resolving stasis and preparation method thereof, strengthening healthy qi and resolving stasis is made from the following weight proportion of raw medicinal materials: Ficus pumila 2g~50g / portion, radix pseudostellariae 2g~50g / portion, poria cocos 2g~50g / portion, atractylodes 2g~50g / portion, radix scutellariae 2g~50g / portion, oldenlandia 2g~50g / portion, cat's paw grass 2g~50g / portion, giant knotweed 2g~50g / portion, curcuma zedoary 2g~50g / portion, oyster 2g~50g / portion, platycodon 2g~50g / portion, mountain bitterling 2g~50g / portion, half branch orchid 2g~50g / portion. By cell test and the construction NSCLC osimertin drug resistance animal model prove, strengthening healthy qi and resolving stasis of the present application can adjust tumor microenvironment (TME) and inhibit non-small cell lung cancer cell growth of osimertin drug resistance. Not only this, strengthening healthy qi and resolving stasis of the present application can also inhibit common non-small cell lung cancer cell growth. While clinical observation finds, strengthening healthy qi and resolving stasis of the present application can improve insomnia, skin rash, diarrhea and other symptoms of lung accumulation (lung cancer, lung nodule) patient, improve its quality of life.

The application discloses application of a traditional Chinese medicine composition in preparation of a medicine for treating vaginitis, and preparation raw materials of the traditional Chinese medicine composition include zedoary turmeric and Chinese atractylodes rhizome. The traditional Chinese medicine composition can kill common pathogenic bacteria of vaginosis, and has good bacteriostatic effect. While inhibiting the common pathogenic bacteria of vaginosis, the traditional Chinese medicine composition does not inhibit lactobacillus of vagina. The traditional Chinese medicine composition can not only kill single common pathogenic bacteria of vaginosis, but also relieve trichomonas vaginalis, and inhibit mixed infection of bacteria and fungi.

This invention discloses a pharmaceutical composition and its preparation method for treating atrophic gastritis, precancerous lesions of the stomach, and stomach cancer, belonging to the field of traditional Chinese medicine preparation technology. The pharmaceutical composition is prepared by a specific two-step microbial fermentation process using Astragalus membranaceus, Hericium erinaceus, Curcuma zedoaria, Actinidia chinensis root, Camptotheca acuminata fruit, Hedyotis diffusa, Coptis chinensis, Taraxacum mongolicum, Viola yedoensis, Corydalis yanhusuo (processed with vinegar), Phellodendron chinense, Solanum nigrum, Scutellaria baicalensis, Panax notoginseng, Zingiber officinale, Piper cubeba, Cuttlebone, Fritillaria thunbergii, roasted soybean, and red yeast rice. This invention significantly improves the bioavailability of the active pharmaceutical ingredients through the synergistic effect of the multifunctional groups of traditional Chinese medicine and the enhanced effect of microbial fermentation. It can systematically reverse gastric mucosal atrophy and intestinal metaplasia, effectively improve microcirculation, and inhibit Helicobacter pylori, while also exhibiting good safety. This provides a novel and effective treatment for the aforementioned gastric diseases.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating chronic atrophic gastritis and a preparation method of the traditional Chinese medicine composition. Comprising the following raw materials: 2-30 parts of astragalus membranaceus, 2-30 parts of bighead atractylodes rhizome, 1-30 parts of codonopsis pilosula, 1-30 parts of poria cocos, 1-30 parts of Chinese yam, 1-40 parts of salvia miltiorrhiza, 2-30 parts of rhizoma sparganii, 1-40 parts of curcuma zedoary, 1-20 parts of elecampane, 1-20 parts of fructus amomi, 2-30 parts of pericarpium citri reticulatae, 1-30 parts of rhizoma pinellinae praeparata, 1-30 parts of dried ginger, 5-20 parts of coptis chinensis, 1-30 parts of immature bitter orange, 3-30 parts of endothelium corneum gigeriae galli and 2-30 parts of raw liquorice. The traditional Chinese medicine composition disclosed by the invention can be used for effectively treating clinical symptoms of CAG, reversing atrophy, intestinal metaplasia and dysplasia of mucosa, remarkably improving endoscopic manifestation of a CAG patient and promoting lesion of gastric mucosa to be relieved or disappear. Animal experiments show that the traditional Chinese medicine can reduce and reverse lesions such as gastric mucosa gland atrophy and epithelium intestinal metaplasia of CAG rats. Mitochondrial metabolic disorder is a key link of CAG gland atrophy and can effectively block CAG canceration.

The invention discloses a traditional Chinese medicine compound composition for treating pulmonary nodules and application thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine compound composition comprises 25-30 parts of astragalus membranaceus, 25-35 parts of radix fici simplicissimae, 15-20 parts of bran-fried rhizoma atractylodis macrocephalae, 9-12 parts of rhizoma pinellinae praeparata, 15-20 parts of thunberg fritillary bulb, 5-10 parts of honey-fried ephedra, 10-12 parts of vinegar-processed curcuma zedoary, 10-15 parts of salvia chinensis, 25-30 parts of radix ranunculi ternati, 12-15 parts of radix curcumae, 10-15 parts of bran-fried fructus aurantii, 12-15 parts of malt, 12-15 parts of poria with hostwood, 25-30 parts of oyster, 10-15 parts of albizia flower, 10-15 parts of liquorice soaked earthworm, 10-20 parts of lucid ganoderma and 10-15 parts of loofah sponge The traditional Chinese medicine composition is used for treating pulmonary nodules, has the effects of invigorating spleen and tonifying lung qi, reducing phlegm and activating blood circulation to dissipate stagnation, has a good treatment effect on pulmonary nodules, is high in safety and can be popularized and applied, and a new traditional Chinese medicine formula is provided for treating lung deficiency and phlegm accumulation type pulmonary nodules.

The invention belongs to the technical field of cardiovascular disease treatment medicines, and particularly relates to a traditional Chinese medicine composition for qi deficiency, blood stasis and phlegm stagnation type coronary heart disease as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises codonopsis pilosula, astragalus membranaceus, dogwood, rhizoma anemarrhenae, platycodon grandiflorum, radix bupleuri, rhizoma cimicifugae, rhizoma sparganii, curcuma zedoary, cassia twig, trichosanthes kirilowii maxim, allium macrostemon, rhizoma pinelliae preparata, Chinese yam and honey-fried licorice root. The traditional Chinese medicine composition can tonify qi, activate blood, eliminate phlegm and resolve turbidity, can be used for treating qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, and can treat both symptoms and root causes. Experiments prove that for a mouse with coronary heart disease, the traditional Chinese medicine composition can obviously improve the heart function of the mouse, and has the effects of inhibiting atherosclerosis and regulating lipid metabolism; for patients with qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, the traditional Chinese medicine composition can improve the symptoms of chest pain and chest distress of the patients. Therefore, the traditional Chinese medicine composition can be used for preparing a medicine for treating qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, and can also be used for preparing a medicine for regulating blood fat.

The invention discloses a traditional Chinese medicine composition for treating delayed absorption of qi-yin deficiency and lung collateral obstruction type pneumonia, a preparation and application. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 10 to 15g of radix pseudostellariae, 10 to 15g of radix asparagi, 6 to 10g of cortex mori radicis, 6 to 10g of radix scutellariae, 6 to 10g of radix platycodonis, 6 to 10g of exocarpium citri grandis, 6 to 10g of bulbus fritillariae thunbergii, 10 to 15g of pericarpium trichosanthis, 10 to 15g of spica prunellae, 15 to 30g of raw oyster shell, 6 to 10g of earthworm, 10 to 15g of radix salviae miltiorrhizae, 6 to 10g of rhizoma curcumae and 6 to 10g of raw liquorice root. The traditional Chinese medicine composition is suitable for delayed absorption of pneumonia caused by deficiency of both qi and yin and obstruction of lung collaterals, and also can be used for treating deficiency-heat syndrome and deficiency-cold syndrome on the basis of the formula, so that the aim of treating due to symptoms is fulfilled. The prescription is used for treating both symptoms and root causes of patients with deficiency of both qi and yin, internal stagnation of phlegm and blood stasis and lung collateral obstruction in delayed absorption of pneumonia on the basis of the basic treatment principles of tonifying lung and yin, reducing phlegm and softening hard mass, and promoting blood circulation to remove meridian obstruction. Clinical research finds that the pharmaceutical composition can improve clinical symptoms of patients with delayed absorption of pneumonia and promote inflammatory absorption, and is relatively safe.

The invention relates to a body resistance strengthening and stagnation eliminating prescription for resisting non-small cell lung cancer and a preparation method thereof. The body resistance strengthening and stagnation eliminating prescription is prepared from the following raw material medicines in parts by weight: 2-50g / part of radix fici simplicissimae, 2-50g / part of radix pseudostellariae, 2-50g / part of poria cocos, 2-50g / part of rhizoma atractylodis macrocephalae, 2-50g / part of radix scutellariae, 2-50g / part of oldenlandia diffusa, 2-50g / part of radix ranunculi ternati, 2-50g / part of polygonum cuspidatum, 2-50g / part of curcuma zedoary, 2-50g / part of oyster, 2-50g / part of platycodon grandiflorum, 2-50g / part of edible tulip and 2-50g / part of sculellaria barbata. Cell tests and construction of an NSCLC osimertinib-resistant animal model prove that the body resistance strengthening and stagnation eliminating prescription can regulate a tumor microenvironment (TME) and inhibit growth of osimertinib-resistant non-small cell lung cancer cells. In addition, the formula for strengthening the body resistance and removing stasis can also inhibit growth of common non-small cell lung cancer cells. Meanwhile, clinical observation finds that the body resistance strengthening and stasis removing prescription can improve symptoms such as insomnia, rash and diarrhea of patients with lung accumulation (lung cancer and pulmonary nodule), and improve the life quality of the patients.

The invention relates to turtle shell pills for eliminating symptoms and a preparation method thereof. According to the technical scheme, the traditional Chinese medicine preparation comprises 47 g of scalded leech, 35 g of ground beetle, 70 g of fried endothelium corneum gigeriae galli, 94 g of vinegar turtle shell, 59 g of vinegar curcuma zedoary, 59 g of vinegar rhizoma sparganii, 94 g of fried peach kernel, 23 g of centipede, 1117 g of astragalus membranaceus, 35 g of mangnolia officinalis, 94 g of vinegar myrrh, 35 g of lindera aggregata, 18 g of rheum officinale, 1117 g of codonopsis pilosula and a proper amount of corn starch, the fourteen traditional Chinese medicinal materials are selected, cleaned and dried respectively and then are crushed until a fine powder state is achieved, the fine powder is uniformly mixed, and the traditional Chinese medicine preparation is prepared. And adding a proper amount of corn starch to prepare a soft material, preparing pills by a pill making machine, and drying the prepared pills to obtain the finished turtle shell pills for eliminating diseases. The traditional Chinese medicine composition has the beneficial effects that through scientific and reasonable formula combination and a fine preparation process, the effects of promoting blood circulation to remove blood stasis and eliminating diseases and dissipating binds are achieved; the preparation process is simple, convenient and feasible, the quality is controllable, and the finished product is stable in character.