A spleen invigorating anti-diarrheal paste is composed of the following main raw materials in parts by weight: 15 parts of Chinese angelica, 12 parts of poria cocos, 25 parts of chicken's gizzard membrane, 25 parts of fried medicated leaven, 25 parts of malt, 25 parts of haw, 15 parts of bitter orange, 12 parts of magnolia cortex, 15 parts of cinnamon, 10 parts of fennel, 10 parts of ligusticum wallichii, 15 parts of radix rehmanniae preparata, and 20 parts of Chinese yam; and also comprises auxiliary materials of sesame oil and yellow lead. Chinese angelica, poria cocos, chicken's gizzard membrane, fried medicated leaven, malt, haw, bitter orange, magnolia cortex, cinnamon, fennel, ligusticum wallichii, radix rehmanniae preparata, and Chinese yam are compounded to generate a synergetic effect to strengthen the paste's functions of tonifying the spleen, boosting the stomach, regulating qi, moving stagnation, relieving pains, and stopping diarrhea. The paste can be directly absorbed by the skin and directly act on the affected part so as to affectively treat infantile anorexia, stomachache, and diarrhea.