The invention discloses a preparation method of
hemerocallis citrina nano-composite micro
powder with high flavone release rate, which comprises the following steps: carrying out
freeze drying treatment on fresh
hemerocallis citrina, carrying out preliminary crushing, mixing the freeze-dried
hemerocallis citrina with an auxiliary material and a disintegrating agent, carrying out infrasonic
resonance treatment, taking microspheres as a force application medium in the process, carrying out
acoustic resonance treatment, mixing, and screening to remove large particles, so as to obtain the hemerocallis citrina nano-composite micro
powder with high flavone release rate. The day lily nano composite micro
powder is obtained. The
processing process does not need any
solvent or additional chemical
reagent, does not have excessive
moisture and
solvent residue, is good in safety, realizes
superfine grinding and self-emulsification of the raw materials under the action of
infrasound resonance force application, improves the release of flavone in an
aqueous solution, and improves the product quality. Meanwhile, the inclusion material can further react with insoluble flavone in the day lily to form an
inclusion compound and an intermolecular complex, so that the hydrophilicity is improved, and effective substances are promoted to be directly dissolved out, and therefore,
after treatment, the capacities of resisting depression and promoting
intestinal peristalsis are improved, and the aim of reducing the intake of the day lily under the same dosage is fulfilled.