15 results about "Intestinal peristalsis" patented technology

The application provides application of Lactobacillus paracasei K56 in preparation of products for improving intestinal peristalsis and promoting defecation, and relates to the technical field of biotechnology. The application comprises application of Lactobacillus paracasei K56 in preparation of products containing at least one efficacy of improving small intestinal propulsion rate of a subject, promoting intestinal peristalsis of the subject and promoting defecation of the subject, wherein the products comprise a fermentation product fermented by using a fermenting agent containing Lactobacillus paracasei K56, and the fermentation substrate contains milk; and the application comprises increasing the proportion of the number of dead Lactobacillus paracasei K56 cells in the fermented product relative to the total number of Lactobacillus paracasei K56 cells. The application alleviates the technical problem that inactivation of bacteria in a fermented product causes the probiotic function to be affected.

The application relates to the field of biological transformation, and particularly discloses a spleen and stomach health type biological transformation beverage and a preparation method thereof. The spleen and stomach health type biological transformation beverage comprises a fermentation liquor, concentrated apple juice, xylitol and stevioside, the raw materials of the fermentation liquor comprise Hericium erinaceus, ginseng, Poria cocos, Myristica fragrans (fried), Chinese yam, Lablab albumus (fried), lotus seed, Coix lachryma-jobi (fried), Amomum villosum, licorice and water, and the fermentation liquor is formed by biological transformation of the raw materials under the action of compound probiotics. The fermentation raw materials of the application modify the traditional ancient prescription of Shenlingbaizhu powder, increase the Hericium erinaceus which is commonly seen and low-fat and high-protein, combine common food and medicine-food homologous substances, are suitable for people with weak spleen and stomach, indigestion and diabetes, and have the advantages of richer nutrition, long-term edible, no toxic and side effects, healthy spleen and stomach and promotion of intestinal peristalsis.

This invention relates to the field of food technology, and in particular to a protein powder that promotes bowel movements. To address the problems of some protein powders with added dietary fiber, such as poor compatibility between dietary fiber and protein, poor solubility, rough texture, and insignificant bowel improvement effects, ultimately leading to constipation, this invention comprises whey protein powder, casein powder, inulin, fructooligosaccharides, psyllium husk powder, soybean lecithin, and β-mannanase. This protein powder offers dual benefits of protein supplementation and intestinal health regulation. It efficiently supplements the protein needed by the human body, improves protein absorption and utilization, and is suitable for individuals with lactose intolerance and weak intestinal function. Simultaneously, through the synergistic effect of prebiotics, dietary fiber, and enzymes, it gently improves constipation symptoms, regulates intestinal flora balance, enhances intestinal peristalsis, and fundamentally protects intestinal health.

The present application relates to the field of probiotics and prebiotics, and in particular to the use of Citrus aurantium, Chichorium intybus, Elsholtzia stauntoni and Hamamelis virginiana as prebiotic mimics (pseudobiotics) that are both medicinal and edible. We first demonstrated that the water extracts of these medicinal and edible herbs significantly improved the constipation symptoms of model mice, improved the pathological damage of the colon of constipated mice, significantly increased the expression of proteins related to intestinal peristalsis and maintenance of the intestinal barrier, promoted the colonization of beneficial bacteria in the intestines of constipated mice, and exhibited effects similar to prebiotics. Therefore, any one of Citrus aurantium, Chichorium intybus, Elsholtzia stauntoni and Hamamelis virginiana or a combination thereof, or a mixture prepared with other substances, can be used to treat constipation in mice, and the mechanism of action may be related to promoting intestinal peristalsis, enhancing the function of the intestinal barrier, and increasing the abundance of beneficial bacteria in the intestines.

This invention discloses a traditional Chinese medicine composition for improving diarrhea, belonging to the field of traditional Chinese medicine technology. Addressing the shortcomings of existing antidiarrheal techniques, which only treat the symptoms and not the root cause, have significant side effects, high recurrence rates, and easily cause damage to the intestinal microcirculation, this invention is based on the original microscopic pathogenesis of small intestinal microvascular spasm and ischemia, and abnormal intestinal fluid metabolism. It is prepared by combining peppermint, angelica dahurica, nutmeg, cinnamon, platycodon grandiflorus, and angelica sinensis. The synergistic effect of each herb can target and relax spasmodic small intestinal microvessels, restore normal intestinal blood perfusion, regulate intestinal peristalsis rhythm, bidirectionally regulate intestinal fluid secretion and reabsorption, and simultaneously block abnormal stress signals in the brain-gut axis, repairing intestinal microcirculatory damage. This invention has a scientifically formulated composition, mild medicinal properties, and no side effects. It addresses the root causes of various acute, chronic, and functional diarrheas caused by cold stimulation, emotional stress, and spleen deficiency with cold stagnation, exhibiting strong curative effect and an extremely low recurrence rate, possessing high clinical promotion and application value.

The present invention relates to the field of probiotics, in particular to an Akkermansia muciniphila MG784 for alleviating constipation, promoting defecation, improving intestinal barrier function and intestinal immunity, and its uses. The Akkermansia muciniphila MG784 provided by the present invention has the deposition number DSM 35549. The Akkermansia muciniphila MG784 provided by the present invention can increase the levels of motilin (MTL), gastrin (GAS), and acetylcholine in the gastrointestinal tract, promote intestinal peristalsis, improve the small intestine propulsion rate, and ameliorate defecation time and fecal output. Furthermore, Akkermansia muciniphila MG784 can also alleviate colonic mucosal inflammation, improve the thickness of the digestive tract muscular layer, modulate the structure of the intestinal microbiota, significantly increase the abundance of beneficial bacteria, and decrease the abundance of harmful bacteria.

This invention provides a traditional Chinese medicine preparation for treating or relieving functional constipation in children, belonging to the field of traditional Chinese medicine technology. The preparation is made from raw Atractylodes macrocephala, banana root, Citrus reticulata, mulberry, Lophatherum gracile, Hovenia dulcis leaf, Ziziphus jujuba leaf, Pogostemon cablin, Citrus reticulata peel, Torreya grandis seed, and licorice. This traditional Chinese medicine preparation significantly increases the number of fecal particles in constipation model rats over 24 hours, increases fecal water content, and improves intestinal propulsion rate, thus improving intestinal peristalsis. In clinical observation, this traditional Chinese medicine preparation effectively relieves the core symptoms of children, shortens the interval between defecation, softens stool, and alleviates straining during defecation. It also improves accompanying symptoms such as abdominal distension and halitosis. After the course of treatment, bowel regularity returns, and there is no significant recurrence during follow-up, providing a new option for the clinical treatment of functional constipation in children.

This invention discloses an intelligent monitoring and auxiliary intervention device for gastrointestinal function recovery after endometriosis surgery, belonging to the field of postoperative rehabilitation nursing device technology. The device includes an abdominal bandage, a control unit fixed to its outer layer, and an array of bowel sound acquisition sensors and a feedback massage unit fixed to its inner layer. The control unit includes a processing and evaluation module for performing time-frequency transformation, noise reduction, and feature extraction on the bowel sound signals acquired by the sensor array. It also intelligently assesses the state of intestinal peristalsis by classifying persistently abnormal weak signal fragments, thereby generating intervention control commands. The feedback massage unit executes tactile stimulation according to these commands. The device can also integrate a drainage tube fixing clip and an activity monitoring sensor. This invention achieves dynamic and objective monitoring of postoperative gastrointestinal function and precise, personalized auxiliary intervention, which helps promote the recovery of intestinal peristalsis, reduce the risk of complications, and improve nursing efficiency.

The application provides a stoma irrigation device, belonging to the field of stoma irrigation, and used for solving the problem of limited physical stimulation to the intestinal tract during stoma irrigation operation; the device comprises an insertion unit, a first liquid injection unit and a second liquid injection unit; the insertion unit comprises a first expansion piece, a second expansion piece and a flow rate adjusting piece arranged in sequence along an insertion direction; the first expansion piece is arranged, and the first liquid injection unit is used to inject gas or liquid into the first expansion piece, so that the first expansion piece is expanded, thereby fixing the insertion unit in the intestinal tract and avoiding leakage of the irrigation liquid; the second liquid injection unit is used to inject the irrigation liquid into the second expansion piece, so that the second expansion piece is expanded to actively induce intestinal peristalsis, change the traditional passive flushing mode, make the intestinal contents more easily softened and removed by peristalsis, shorten the cleaning time and improve the cleanliness; and the irrigation liquid enters the intestinal tract at a slow speed after being adjusted by the flow rate adjusting piece, so that the intestinal mucosa is protected and the discomfort of the patient is reduced.

The present application relates to the field of biomedical engineering, and particularly relates to a pump-free intestinal chip system capable of measuring transmembrane resistance value and a measuring method thereof.The system comprises transmembrane resistance measuring electrodes, an intestinal chip and a swing-type shaker; the intestinal chip is composed of a plurality of chip units arranged in parallel, and each chip unit comprises, from top to bottom, a culture layer, a porous membrane and a perfusion layer; the culture layer is provided with a first end hole, an intermediate hole and a second end hole in sequence, both end holes are communicated with the cavity of the perfusion layer to form a fluid channel, the intermediate hole is used for culturing cells, and the intermediate hole separates the culture layer and the perfusion layer and exchanges materials through the porous membrane; the swing-type shaker is used for providing periodic gravity flow to simulate intestinal peristalsis; the transmembrane resistance measuring electrodes are connected with a resistance meter, and the transmembrane resistance value is obtained through current-voltage measurement.The present application has better simulation of intestinal barrier characteristics, can measure the transmembrane resistance value of the intestinal chip, and is convenient to operate and short in time consumption.

The application discloses a garden ginseng extract and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine preparations. The garden ginseng extract contains a large amount of active ingredients, can improve the body's antioxidant, anti-inflammatory, anti-ischemic and anti-apoptotic capacity, protect myocardial cells and blood vessels, reduce damage, stabilize heart rhythm, improve coronary blood supply, and obtain excellent heart-protecting effect; promote intestinal peristalsis, improve intestinal health, improve the body's absorption and utilization capacity of nutrient substances, promote toxin discharge, provide sufficient raw materials and suitable environmental conditions for damaged cell repair and regeneration; assist in reducing blood lipids and cleaning vascular lipids, promote / maintain vascular health; the preparation method has mild conditions, does not use organic reagents, has no safety hidden trouble, can greatly improve the beneficial effect and utilization rate of the garden ginseng, and has definite conditions, can standardize production and popularize on a large scale.

This invention discloses a compound probiotic feed for livestock and poultry that optimizes protein and energy supply, and its preparation method. In this invention, by flexibly adjusting the ratio of protein raw materials and energy components, targeted nutritional supply is provided for growing-finishing pigs, commercial laying hens, and broiler poultry. Fermented soybean meal and fermented alfalfa meal, after premixing and fermentation, not only retain the natural nutrients in the raw materials but also degrade anti-nutritional factors through microbial fermentation. Combined with high-quality animal protein from imported fishmeal, a protein system more easily digested and absorbed by livestock and poultry is constructed. The addition of the compound probiotic preparation can form a dominant bacterial community environment in the livestock and poultry intestines, promoting intestinal peristalsis and digestive enzyme secretion, further improving the conversion rate of nutrients in the feed, reducing nutrient loss in the intestines, helping livestock and poultry grow rapidly, improving overall breeding efficiency, effectively improving the intestinal health of livestock and poultry, and reducing the incidence of diseases during the breeding process.

The application provides a low-carbon probiotic preparation and a preparation method thereof, and belongs to the technical field of probiotics. Carbon dioxide is introduced into a low-eutectic solvent, immobilized Mannheim succinic acid producing bacteria are added, fermentation culture is carried out, separation is performed, probiotics are inoculated in a liquid, fermentation culture is carried out, and then the low-carbon probiotic preparation is prepared through polylactic acid embedding. The low-carbon probiotic preparation prepared by the application firstly utilizes a CO2-resistant strain to convert carbon dioxide into an organic carbon source, thereby promoting the proliferation of probiotics. After embedding in polylactic acid, the low-carbon probiotic preparation can well resist gastric acid and is released in an intestinal alkaline environment, appropriately releases CO2 gas, utilizes CO2 to promote intestinal peristalsis, the probiotic can also inhibit inflammatory factors, thereby can inhibit intestinal inflammation, has a good promoting effect on postoperative rehabilitation, and has a wide application prospect.

The present application belongs to the field of pet food and biomedicine, and discloses a compound probiotic composition with the effect of biodegradation of hair balls and application thereof. The composition comprises Weizmannia coagulans, Bacillus subtilis and oil-tea camellia seed extract. The oil-tea camellia seed extract from a specific source is used as a biological surfactant to emulsify and break the "oil seal" sebum layer on the surface of pet hair, significantly reduce the surface tension of the hair, induce keratinase secreted by Bacillus subtilis to be efficiently wetted and adsorbed on the hair fiber, and realize deep biodegradation of keratin. At the same time, lactic acid produced by Weizmannia coagulans promotes intestinal peristalsis, and the decomposition and excretion of hair balls are realized in cooperation. The experimental results show that the cat hair dry weight loss rate of the composition is 65%-78%, the frequency of vomiting can be effectively reduced, and the composition has excellent acid stability, palatability and safety.