151 results about "Alimentary tract" patented technology

The invention discloses application of a gene marker in early screening of esophagus, stomach and intestine multiple cancer species, an early screening model construction method and a detection device, and belongs to the technical field of early noninvasive detection of digestive tract tumors. By analyzing the whole genome characteristics of circulating free DNA in peripheral blood, a novel multi-cancer-species screening system is established. On the basis of low-depth whole genome sequencing data, molecular markers in three dimensions, namely a genome copy number variation mode, a DNA fragment distribution characteristic with a specific length and an epigenetics signal of a transcription initiation region, are emphatically detected. An advanced converter neural network architecture is adopted, and the model can efficiently capture complex feature association in a whole genome range through a specific self-attention mechanism. The model design particularly considers the particularity of genome data, introduces an adaptive position coding system, and accurately reflects the spatial distribution relationship of DNA fragments on chromosomes. Therefore, the system can still maintain excellent detection performance under extremely low sequencing depth.

The invention relates to the technical field of artificial intelligence, and provides a gastric cancer risk quantitative scoring method, system and equipment based on artificial intelligence, and the method comprises the steps: recognizing the image type of each image frame in alimentary canal endoscope image data; for the electronic dyeing image frame, identifying a part contour region and an intestinal contour region of the feature part in the image frame, determining an intestinal epithelial metaplasia grading category of the feature part according to an area proportion of the intestinal contour region in the part contour region, and performing electronic dyeing intestinal scoring on the image data; for the white light image frame, gastroscope part types included in the image frame and focus area types of all gastroscope parts are recognized; performing atrophy scoring on the image data according to the position distribution of the focus area of the atrophy type; performing table state scoring on the image data according to whether the plica enlargement, nodular gastritis and diffuse redness focus areas exist or not; and realizing gastric cancer risk quantitative scoring according to the electronic staining intestinal scoring, the atrophy scoring and the epistatic state scoring.

The invention discloses a non-invasive intestinal flora fixed-point sampling and drug release device, and belongs to the technical field of micro-ecological diagnosis and treatment. The device comprises a shell, an internal storage bin, a medicine loading cavity and a channel switching mechanism. The shell adopts a capsule-shaped design, and an enteric coating is arranged on the surface of the shell, so that the function is started after the shell reaches a specified position of an intestinal tract. Through the internal ingenious mechanism linkage design, the device can firstly complete non-invasive fixed-point sampling of intestinal contents, and after the sampling action is completed, a drug release mechanism is automatically triggered, so that accurate drug delivery of the same part is realized. Cooperative operation of sampling and drug release in time sequence and space is achieved, and the problems of pain, disjunction of the diagnosis and treatment process, poor drug targeting and the like caused by traditional invasive operation are effectively solved. The device is flexible in structural design, has the advantages of being noninvasive, efficient, accurate in time sequence control and the like, and is suitable for integrated application of diagnosis and treatment of various digestive tract diseases such as inflammatory bowel disease management, micro-ecological regulation and the like.

A magnetic drive soft capsule robot and system comprises a miniature camera, a flexible foldable skin and an internal drive permanent magnet, the miniature camera is installed on a capsule formed by the flexible foldable skin, the flexible foldable skin is provided with a flexible fold type structure which can be folded or stretched in the length direction of the capsule and can be bent, and the internal drive permanent magnet is installed on the flexible fold type structure. The soft capsule robot comprises a capsule, a miniature camera and an internal driving permanent magnet, the internal driving permanent magnet is arranged in the capsule, the miniature camera is used for collecting images, and the internal driving permanent magnet is used for driving the flexible foldable skin to deform and move under the action of an external magnetic field, so that the posture and the movement track of the soft capsule robot are controlled. The magnetically-driven soft capsule robot is suitable for narrow and multi-curve digestive tracts, and can overcome the limitations that the posture of a current wireless capsule for endoscopic disease diagnosis cannot be actively controlled in real time, and discomfort or jamming is caused by a rigid shell.

The invention discloses a digestible quality analysis system for chicken feed, relates to the technical field of chicken feed analysis, and aims to solve the problem of poor simulation effect of digestion of the chicken feed. According to the method, low-temperature and high-temperature staged drying treatment is adopted, the characteristics of components such as moisture and fat in the residues are fully considered, the secretion rules of different alimentary canal parts of animals are simulated, sufficient and reasonable contact of digestive juice and feed is ensured, the simulation process is closer to the real physiological condition, and the situation that the digestion analysis result is affected by liquid amount errors is avoided; animal digestive tracts are scientifically segmented into stomach, small intestine and large intestine stages, corresponding external buffer solution and internal digestive juice are injected respectively, and a real digestion scene is comprehensively simulated from a physical structure to a chemical environment.

The invention discloses anti-inflammatory polypeptide nanoparticles and a preparation method thereof, and belongs to the technical field of bioactive peptides. The anti-inflammatory polypeptide nano-particles are nano-particles obtained by coating polypeptide with an anti-inflammatory effect with chitosan and sodium tripolyphosphate, the polypeptide with the anti-inflammatory effect contains bioactive peptides of which the amino acid sequences are YAADQ, FPYTT and YVTYA. The phycocyanin anti-inflammatory peptide is natural in source, the performance of the phycocyanin anti-inflammatory peptide can be remarkably improved through the nanometer embedding technology, and compared with traditional drugs, the phycocyanin anti-inflammatory peptide has lower toxic and side effects and potential cost advantages. The polypeptide nanoparticles prepared by the invention can effectively prevent the phycocyanin anti-inflammatory peptide from being degraded in the digestive tract, have a remarkable treatment effect on mice with ulcerative colitis, and have an important application prospect in preparation of ulcerative colitis prevention and treatment products.

The application provides a multifunctional catheter, comprising a catheter main body and a distal tube with a multi-cavity tube structure. The distal tube comprises a soft end at the proximal end and a functional end at the distal end. The catheter main body and the soft end are provided with a working cavity and a lens cavity. The functional end is further provided with a through hole communicating with the lens cavity. The lens cavity is a circular tube cavity structure extending along the catheter main body and the soft end. The inner wall of the lens cavity is provided with a plurality of accommodation grooves for accommodating photosensitive chips in a lens assembly. The catheter provided by the application can form a space for accommodating photosensitive chips through the plurality of accommodation grooves in the lens cavity, and the lens assembly can be installed without increasing the diameter of the lens cavity, thereby reducing the overall diameter of the catheter to adapt to the more complex bile duct environment relative to the digestive tract.

The invention discloses a linear cutting and closing device for polyp resection under an endoscope, relates to the technical field of medical closing devices, and aims to solve the technical problems that perforation is easily generated in linear cutting and closing cutting, and repeated cutting is needed. Magnetic attraction linkage is taken as a core, the clamping force of the closed clamp is accurately controlled through the first magnetic attraction block, and a fine adjustment structure and a clamping limiting design are matched, so that sufficient clamping and one-time complete excision of a polyp are realized, and multiple times of cutting are avoided; the flexible lead body and the miniaturized structure are matched with an endoscope channel, so that the operation flexibility of a complex digestive tract is improved; the automatic conveying and clamping structure can immediately close the wound surface, and the bleeding and perforation risks are reduced; the whole-course button control simplifies operation, the elastic reset assembly reduces manual steps, and the operation time is shortened. The operation safety, the operation convenience and the adaptability are considered on the whole, the complication occurrence rate is effectively reduced, and the clinical treatment effect and efficiency of the endoscopic polyp resection operation are remarkably improved.

The present invention relates to an equipment for magnetic recanalization of benign biliary strictures. The equipment (100) includes a wire-guided magnet pusher tube (102a), atleast one magnet (110), and a magnet retrieval tube (102b). The equipment (100) works in conjunction with a visualization system to guide placement of the magnet (110) at the target site for recanalization of the biliary stricture. The magnet (110), may be deployed at opposing ends of a biliary stricture to create a controlled recanalization channel via magnetic attraction. The deployment process can be performed using endoscopic retrograde cholangiopancreatography (ERCP), percutaneous transhepatic biliary drainage (PTBD), or a combination of both. Magnets may be retrieved following recanalization using biopsy forceps or allowed to pass naturally through the digestive tract, avoiding permanent implantation.

The present invention relates to a chair-based capsule endoscope control device and system for controlling a capsule endoscope that is inserted into the human digestive system and acquires images of organs. The present invention provides a capsule endoscope control device that is inserted into the digestive tract of a subject and controls the position or posture of a capsule endoscope equipped with a magnet. The device comprises: a chair for the subject to sit on, comprising a seat portion and a backrest connected to the seat portion; and a magnet controller disposed on the backrest. The magnet controller includes a control magnetic force generator for adjusting the position or posture of the capsule endoscope, wherein the control magnetic force generator is movable in at least one direction.

The invention relates to the technical field of medical instrument simulation and testing, in particular to a high-precision 3D printing personalized alimentary canal entity model method which comprises the steps that alimentary canal CT image data covering the range from the nasal cavity to the jejunum of a target individual and biomechanical property reference data of different sections of the alimentary canal are obtained; generating a stiffness distribution diagram; transparent flexible photosensitive resin is used as a base material, and various transparent flexible photosensitive resin materials with different elastic moduli are prepared by adding a modifier; generating a printing instruction; a digital light processing 3D printer is adopted, a solid model is printed layer by layer according to a printing instruction, the distributed transparent flexible photosensitive resin material is automatically switched and used in the printing process, and exposure parameters of ultraviolet light are dynamically adjusted based on the characteristics of the currently used transparent flexible photosensitive resin material so as to control the post-curing elastic modulus of different sections. Through accurate elastic modulus control and dynamic exposure adjustment, the mechanical properties of different sections of the digestive tract are highly consistent with the actual situation.

This invention belongs to the field of medical device technology, specifically a surgical treatment device for digestive tract malformations. It includes a support plate and casters, all fixedly connected to the bottom of the support plate. An adjustment mechanism is located on the top of the support plate, and a replacement mechanism is located on the top of the adjustment mechanism. The adjustment mechanism includes a cylindrical body fixedly connected to the top of the support plate. A vertical rod is inserted into the cylindrical body, and limit grooves are formed on both sides of the cylindrical body. Limit plates are inserted into the limit grooves, and support rings are fixedly connected to the surface of the limit plates. Fixing plates are fixedly connected to both sides of the cylindrical body. This surgical treatment device for digestive tract malformations allows for height adjustment by threading a fixing bolt into a threaded hole inside the fixing plate when the vertical rod is moved to a suitable height, ensuring the stability of the device during surgery.

This invention discloses a capsule system for electro-adhesion in the digestive tract and its operating method, relating to the field of medical devices. The system includes a transparent outer shell forming a sealed cavity within it; multiple electrode adhesion units are axially arranged on the outer wall of the shell; an image acquisition device is fixed inside the shell, with its acquisition end adjacent to the transparent end of the shell; a wireless transmission device is used for bidirectional wireless data transmission with an external workstation; when the drug storage device's release port is open, the drug within the storage device can be released to the outside; a control module can control the opening and closing of the release port, and can control the power supply to the electrode adhesion units, as well as the direction of current flow after power is applied; a power supply is electrically connected to the image acquisition device, the wireless transmission device, the drug storage device, and the control module. The system and its operating method of this invention can save internal capsule space, avoid mechanical damage to intestinal wall tissue, and the anchoring and release process is rapid, controllable, and reversible.

The balloon structure comprises a main catheter and a one-way valve arranged on one side of the main catheter, an auxiliary catheter is arranged on one side of the main catheter, the auxiliary catheter is detachably connected with the main catheter through a connecting mechanism, a hollow gooseneck pipe is arranged on one side of the auxiliary catheter, and the hollow gooseneck pipe is detachably connected with the main catheter through a connecting mechanism. A bag body structure is arranged on one side of the auxiliary catheter; the bag body structure comprises a hollow bag body, the bottom face of the hollow bag body is arranged on the outer surface of the auxiliary catheter, multiple sets of water inlet pipes are further arranged on one side of the auxiliary catheter and communicated with the hollow bag body, and an adjusting ring is further arranged on one side of the hollow bag body and slidably arranged on the auxiliary catheter. The angle of the hollow bag body can be adjusted according to the bending angle of the digestive tract, the hollow bag body can be conveniently guided in, meanwhile, expansion of the hollow bag body is guided, the sealing performance of the hollow bag body on plugging of the digestive tract is improved, overall installation and operation are convenient, and medical staff can conveniently use the hollow bag body.

The alimentary canal liquid biopsy sampling device comprises an inner detection part and an outer equipment part, the inner detection part comprises a detection sphere and a spherical shell, the diameter of the detection sphere is smaller than that of the spherical shell, the detection sphere is arranged in an inner cavity of the spherical shell, the spherical shell is hollow, and a magnet part is arranged at one end in the detection sphere; the external equipment part comprises a main body frame, an annular moving part capable of sliding back and forth is arranged on the main body frame, and an electromagnet capable of moving along the inner side wall of the annular moving part is arranged on the inner side of the annular moving part. According to the invention, the internal detection part adopts the detection sphere with the built-in magnetic control and is sleeved with the hollow sphere shell, the detection sphere is isotropic and flexible in steering, the hollow sphere shell rolls during movement, so that the friction force is reduced, the hollow sphere shell is easy to roll in intestinal wrinkles, the rolling speed can be effectively improved, and the magnetic field driving efficiency is effectively improved.

The present invention provides a digestive tract expander, comprising a traction rope, a bracket with an open state and a closed state, the distal end of which is fixedly arranged with the distal end of the traction rope, a push tube slidably sleeved on the traction rope and the distal end of which is fixedly connected to the proximal end of the bracket, a sheath tube slidably sleeved on the push tube, and an operating handle fixedly connected to the proximal end of the sheath tube, the operating handle comprising a shell fixedly connected to the sheath tube, a slider slidably connected to the shell, and a control button connected to the slider and capable of driving the slider to slide, and the push tube is fixedly connected to the slider. The present invention has a simple structure, convenient operation, and obvious effect. It can expand the digestive tract radially and help loosen trapped foreign matter from the mucosal layer.

The protective cover is of a multi-section structure, the multi-section structure comprises a protective section located at the front end, a visual expansion section located in the middle and a gastroscope fixing section located at the rear end, and when a gastroscope is fixed to the gastroscope fixing section, the protective section reversely wraps the gastroscope; and the protection section is made of a medical elastomer material. According to the technical scheme, when foreign bodies in the digestive tract are taken out, mucous membranes of the whole esophagus, the junction of the esophagus and the stomach and the esophagus inlet can be protected, long foreign bodies and sharp foreign bodies can be conveniently taken out under an endoscope, the occurrence rate of complications of the upper digestive tract foreign body taking-out operation is reduced, and the safety and effectiveness of treatment are improved.

The invention belongs to the technical field of biological medicine, and relates to a brain-targeted delivery system of semeglutide as well as a preparation method and application of the brain-targeted delivery system of semeglutide, the delivery system comprises yeast microcapsules and a semeglutide-cationic polymer; the delivery system takes a yeast microcapsule as a delivery carrier, and a semeglutide-cationic polymer is encapsulated in the yeast microcapsule. By simulating a natural way that microorganisms are recognized by macrophages through digestive tracts, active uptake is realized by utilizing specific binding of yeast microcapsules and Dectin-1 receptors on the surfaces of the macrophages, the semeglutide is accurately delivered to the brain by virtue of the cross-blood-brain-barrier migration ability of the macrophages, a central GLP-1 receptor pathway is activated to regulate metabolism, and meanwhile, the semeglutide can be used for preparing a medicine for treating liver cancer. According to the system, the oral bioavailability of the semeglutide can be improved, and non-specific distribution of the whole body is reduced.

This invention belongs to the field of medical drainage technology, specifically a drainage device for the care of gastrointestinal tumors. It includes a valve assembly, a valve adjustment assembly, an automatic cleaning assembly, a frame assembly, a liquid storage assembly, and a gas filtration assembly. The valve assembly is mounted on the frame assembly, and the valve adjustment assembly and the automatic cleaning assembly are located within the valve assembly. This invention cleverly utilizes changes in negative pressure within the valve body to trigger a cleaning action. When deposits on the inner wall obstruct the airflow, the reduced air pressure automatically overcomes the spring force, causing the piston to slide. This, in conjunction with a scraper ring, mechanically scrapes away the blockage from the inner wall of the valve body and pushes the obstruction into an independent storage bottle. This process achieves in-situ unblocking without disassembling the tubing, effectively preventing drainage interruption and significantly reducing the probability of cross-infection.

The present invention relates to the technical field of microorganisms, in particular to a Lactobacillus acidophilus GOLDGUT-LA100 having functions of lipid lowering, blood glucose lowering and weight loss and application thereof. The Lactobacillus acidophilus GOLDGUT-LA100 provided by the present invention is preserved in China General Microbiological Culture Collection Center, with the preservation number of CGMCC No. 28398. The strain has strong acid resistance, can adapt to the digestive tract environment, and has high bile salt hydrolase activity. At the same time, in animal experiments, the strain significantly reduces blood glucose and serum cholesterol levels, reduces liver fat deposition, reduces adipose tissue inflammation, effectively reduces the weight, and has broad application prospects in the development of products for improving obesity, lowering lipid and lowering blood glucose.

The invention discloses an ERCP (endoscopic retrograde cholangiopathy) operation simulation method and an ERCP operation simulation system based on a VR (virtual reality) technology. Establishing a space rectangular coordinate system, constructing a human digestive tract model, and importing the human digestive tract model into the space rectangular coordinate system; constructing a simulation insertion tube and a simulation controller, obtaining an operation signal of the simulation controller for controlling the simulation insertion tube, and transmitting the operation signal to VR equipment; acquiring posture data of the simulated insertion tube under the control of the operation signal, and acquiring the advancing direction and position of the simulated insertion tube in the human digestive tract model based on the posture data; determining the spacing distance between the simulated insertion tube and the inner wall of the human alimentary canal model according to the position, and applying operation feedback to the simulated insertion tube according to the spacing distance and the advancing direction so as to complete simulation of the ERCP operation. According to the simulation method provided by the invention, the ERCP operation process can be truly simulated in a safe environment, and the training and learning efficiency is improved.

An access device used with an endoscope includes an access pipe configured to be inserted into a sheath of the endoscope, a piercer disposed on a distal end portion of the access pipe and configured to pierce into a hollow organ through a digestive tract of a patient, and a treatment tool configured to be inserted into the access pipe and to be introduced into the hollow organ by the piercer. The access device is switchable between a first configuration and a second configuration. In the first configuration, a piercing function of the piercer is switched on, so that the piercer pierces the digestive tract and the hollow organ to enter into an interior of the hollow organ, and in the second configuration, the piercing function of the piercer is switched off, the piercer is kept connected to the interior of the hollow organ.

The invention belongs to the technical field of gastroscope sharp foreign body taking-out devices, and particularly discloses a multi-form adjustable gastroscope sharp foreign body taking-out auxiliary device which comprises a gastroscope head tube, one end of the gastroscope head tube is sleeved with a transparent tube cap, and folding rubber bags are evenly and fixedly installed on the outer surface of an auxiliary connecting end. According to the multi-form adjusting sharp foreign matter taking-out auxiliary device for the gastroscope, after the gastroscope lens tube is fed into the body of a patient and a sharp foreign matter is clamped, endoscope foreign matter forceps can be pulled to enable the sharp foreign matter to be close to the auxiliary connecting end, then air can be injected into the folding rubber bag through the ventilation channel, and the sharp foreign matter can be taken out through the ventilation channel. The folding rubber bag can be gradually expanded and expanded through air injection so as to shield the clamped sharp foreign matter, the sharp foreign matter cannot scratch the interior of the digestive tract of a patient in the taking-out process, secondary damage caused by the sharp foreign matter is reduced, and the comfort degree of the patient after the foreign matter is taken out is improved.

Introduced herein is an ingestible device capable of delivering a drug directly to tissues along the digestive tract. Administration of the drug stored in the ingestible device can be achieved through a combination of features. The ingestible device can include a plunging mechanism to which a needle is connected and a dissolvable trigger mechanism that holds the plunging mechanism in a first position. After ingestion, the trigger mechanism can be exposed to bodily fluids to cause dissolution. When the trigger mechanism dissolves, the plunging mechanism can move from the first position to a second position, thereby extending the needle into the tissue in which the ingestible device is housed. Second, the needle can also dissolve upon exposure to bodily fluids to ensure safe passage of the ingestible device through the digestive tract.

The utility model discloses a sampling capsule for in-situ sampling of a digestive tract. The sampling capsule comprises a capsule shell, a sample cabin door is formed in the capsule shell, a sample cabin, a circuit board and a battery are arranged in the capsule shell, the sample cabin corresponds to the sample cabin door in position, the circuit board is electrically connected with a micro motor, the output end of the micro motor is connected with a gear set, and the gear set is used for amplifying the acting force of the micro motor. The gear set is connected with a sample cabin door on the capsule shell through a transmission shaft; the gear set comprises a driving gear connected with the output end of the micro motor, a driven duplicate gear connected with the driving gear in a meshed mode and a driven gear connected with the driven duplicate gear in a meshed mode. The device can prevent proteins, metabolites and the like from being re-absorbed by colon, can effectively reflect the structures of biome, proteome and metabolome at each stage of the digestive tract, and provides a new device for research on space-time structure of microecology of the digestive tract and composition change of the space-time structure during occurrence and development of diseases.

The present invention relates to a single cell cylindrical battery, such as a button cell or a button battery, that can be regarded to have the shape of a slice of a cylinder, and to a method preventing upper digestive and upper respiratory tract injury after accidental ingestion of the single cell cylindrical battery. It is noted that in some case ingestion has even led to the death in particular of children or small size adults, or people with a mental limitation, or people with a prior narrowing of structures in which the battery can be lodged. The structures in which the battery can be lodged are both the pharyngeal, upper digestive and upper respiratory tracts. As ingestion itself can not always be prevented, a relatively safe battery has been developed, which mitigates problems associated with ingestion.

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating postoperative digestive tract reaction of malignant tumors, a preparation and application. The traditional Chinese medicine composition comprises the following active ingredient raw materials in parts by weight: 10-20 parts of fried codonopsis pilosula, 10-20 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 1-10 parts of liquorice, 10-20 parts of fried endothelium corneum gigeriae galli, 15-25 parts of fried malt, 25-35 parts of adina rubella hance root, 25-35 parts of wild grape root, 15-25 parts of Chinese actinidia root and 15-25 parts of coix seed. The traditional Chinese medicine composition and the preparation can effectively treat patients with malignant tumor postoperative digestive tract reaction, effectively improve symptoms of abdominal distension, stomachache, nausea, vomiting, diarrhea, constipation, anorexia, sour regurgitation, oral cavity / throat dryness and the like of the patients, improve the life quality of the patients and have good safety.

The abdominal cavity drainage fixing device comprises a drainage stabilizing mechanism, an abdominal cavity fixing mechanism and a drainage tube mechanism, the drainage stabilizing mechanism is located on one side of the abdominal cavity fixing mechanism, the drainage tube mechanism is located in the drainage stabilizing mechanism, and the drainage stabilizing mechanism comprises a containing plate; the outer wall of the placing plate is fixedly connected with a hollow column, and one side of the placing plate is fixedly connected with a side plate. By means of the drainage stabilizing mechanism, when a drainage task is conducted after the drainage tube mechanism is connected with a patient, a drainage tube can be fixedly clamped and fixed, the drainage tube can be prevented from falling off accidentally by clamping and fixing the drainage tube, it is ensured that the drainage tube conducts continuous drainage at the correct position, and the position change of the drainage tube can be reduced by fixing the drainage tube; the possibility that bacteria enter a wound is reduced, the risk of infection is reduced, it can be ensured that the drainage tube is not pressed or blocked, smooth drainage is kept, it is ensured that accumulated liquid in the abdominal cavity can be effectively discharged, and meanwhile the stability of the abdomen of a patient is improved through the drainage stabilizing mechanism; and seepage can be reduced and the seepage degree can be reduced.

The present invention relates to a method for reducing lipid binding of brazzein and / or to method for improving digestibility of brazzein in a subject's digestive track as well as to a modified brazzein polypeptide and uses of it and to a nucleic acid encoding the same.

The invention discloses a preparation method and application of probiotic visual hydrogel beads, and relates to the technical field of biology. The preparation method comprises the following steps: uniformly mixing an ALG + SPI solution with a bacterial solution of a probiotic recombinant strain to obtain a mixed solution; dropwise adding the mixed solution into a curing solution by adopting a dropping method, and carrying out cross-linking curing treatment to obtain the probiotic visual hydrogel bead. The ALG + SPI solution is a solution containing sodium alginate and soybean protein isolate; the probiotic recombinant strain is obtained by transforming a recombinant plasmid containing the gfp gene into probiotics. The probiotic visual hydrogel bead has a relatively high embedding rate and excellent stability, and the survival rate of probiotics in a digestive tract environment can be remarkably improved. The probiotic visual hydrogel bead can be used as an ideal probiotic delivery carrier, so that the probiotic visual hydrogel bead can be widely applied to the fields of intestinal health conditioning, probiotic preparation development and the like.