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113 results about "Phycocyanin" patented technology

Phycocyanin is a pigment-protein complex from the light-harvesting phycobiliprotein family, along with allophycocyanin and phycoerythrin. It is an accessory pigment to chlorophyll. All phycobiliproteins are water-soluble, so they cannot exist within the membrane like carotenoids can. Instead, phycobiliproteins aggregate to form clusters that adhere to the membrane called phycobilisomes. Phycocyanin is a characteristic light blue color, absorbing orange and red light, particularly near 620 nm (depending on which specific type it is), and emits fluorescence at about 650 nm (also depending on which type it is). Allophycocyanin absorbs and emits at longer wavelengths than phycocyanin C or phycocyanin R. Phycocyanins are found in Cyanobacteria (also called blue-green algae). Phycobiliproteins have fluorescent properties that are used in immunoassay kits. Phycocyanin is from the Greek phyco meaning “algae” and cyanin is from the English word “cyan", which conventionally means a shade of blue-green (close to "aqua") and is derived from the Greek “kyanos" which means a somewhat different color: "dark blue". The product phycocyanin, produced by Aphanizomenon flos-aquae and Spirulina, is for example used in the food and beverage industry as the natural coloring agent 'Lina Blue' or 'EXBERRY Shade Blue' and is found in sweets and ice cream. In addition, fluorescence detection of phycocyanin pigments in water samples is a useful method to monitor cyanobacteria biomass.

A phycocyanin-collagen composite hydrogel and its preparation method and application

The present invention provides a phycocyanin-collagen composite hydrogel and its preparation method and application. The present invention utilizes transglutaminase to catalyze the combination of phycocyanin and collagen to form a new, more stable collagen; transglutaminase acts between protein molecules, utilizes lysine and glutamic acid in phycocyanin and collagen to transfer acyl groups, and cross-links to form new chemical bonds, thereby enhancing the binding strength of phycocyanin and collagen; the hydrogel prepared by the present invention can be used to prepare medical materials and combined with skin injury sites to solve the problem that traditional dressings are easy to adhere to wounds and easily penetrated by tissue fluid and become infected. In addition to ensuring basic air permeability, it reduces the adhesion of the dressing, increases moisture retention and antioxidant properties, and avoids secondary damage when replacing a new dressing. The hydrogel prepared by the present invention has a certain antioxidant capacity and can be used to prepare products with antioxidant effects.
Owner:SHANDONG UNIV OF SCI & TECH +1

Solid lipid nanoparticles for encapsulation and delivery of bioactive compounds and methods of making the same

Solid lipid nanoparticles (SLNs) for delivery of bioactive compounds are disclosed. The SLNs comprise a lipid matrix and surfactant layer encapsulating at least one bioactive compound selected from vitamins, minerals, enzymes, algae-derived bioactives, proteins, peptides, amino acids, antioxidants, small synthetic molecules, plant-derived volatile compounds, or botanical extracts. The SLNs exhibit submicron particle size, low polydispersity, and sufficient surface charge to ensure colloidal stability and efficient delivery. In one embodiment, algae-based bioactives, such as phycocyanin or fucoxanthin, are encapsulated using only natural and sustainable lipids and surfactants to improve bioavailability and support environmentally friendly formulations. The SLNs may be formulated for oral, topical, transdermal, injectable, ophthalmic, mucosal, textile, veterinary, or agricultural administration. Applications include human and animal health, functional foods, skincare, nutrient supplementation, and crop treatment. The disclosed SLNs offer a biocompatible and scalable delivery system that protects sensitive compounds, enables sustained release, and enhances absorption across diverse industries.
Owner:YUBECK INC

Preparation method and application of high-brightness nitrogen-doped carbon quantum dots based on phycocyanin

The invention belongs to the technical field of nano functional materials and intelligent textiles, and particularly discloses a preparation method and application of high-brightness nitrogen-doped carbon quantum dots based on phycocyanin. The method is used for solving the problems of large difference and poor reproducibility when the same biomass in different batches is used for preparing the carbon dots in the prior art. Comprising the following steps: (1) freeze-drying spirulina, and grinding into powder to obtain spirulina powder; (2) extracting phycocyanin by utilizing spirulina powder; (3) phycocyanin is added into the reaction container, then distilled water is added, the adding amount ratio of phycocyanin to distilled water is 1 g: 33.3-50 mL, and full stirring is conducted; and then, carrying out carbonization treatment, cooling to room temperature, collecting the solution, and dialyzing for 24 hours, so that the solution outside a dialysis bag is a purified carbon quantum dot solution. According to the method, the phycocyanin is used as a single nitrogen source for the first time, the reproducibility of preparing the carbon dots from the same biomass in different batches is good, and large-scale production is facilitated.
Owner:QINGDAO UNIV

Marker composition

A marker composition for application to a medical device or a surface is disclosed. The marker composition comprises a carrier composition including water, nonionic surfactant, organic solvent, and a neutral or anionic viscosity modifier. The marker composition further comprises a dyestuff. In some embodiments, the quantity of dyestuff present is such that at least some of the dyestuff is present as a dispersed solid phase. The dyestuff may be a naturally-derived dyestuff, such as spirulina extract (including phycocyanin). The invention extends to a carrier composition for a dyestuff.
Owner:TRISTEL PCL

Seaweed blue square fermented bean curd and preparation method thereof

The invention discloses a seaweed blue square fermented bean curd and a preparation method thereof. The preparation method comprises the steps of phycocyanin extraction, three-stage fermentation, blank making and mildewing, marinade pickling and after-ripening. According to the invention, a Maillard reaction and fermentation technology combined process is adopted, and synergistic interaction of flavor modification and pigment stability is realized through three-stage temperature gradient control. In the first stage, synchronous optimization of fishy smell removal and structural stability of phycocyanin is realized; in the second stage, Maillard-fermentation staged treatment is carried out to accurately control sulfide cracking; in the third stage, the flavor is solidified, the acid resistance of phycocyanin is remarkably improved, and an obvious seafood flavor is formed. The method effectively solves the problems of fishy smell residue, color deterioration and texture fusion in phycocyanin processing. The innovation of the composite plant marinade endows the product with unique flavor, and the final product shows stable sky-blue color by cooperating with the mucor post-fermentation, so that a novel fermented bean curd product with unique blue appearance, excellent flavor and nutritional value is developed.
Owner:OCEAN UNIV OF CHINA

Anti-inflammatory polypeptide nanoparticles and preparation method thereof

The invention discloses anti-inflammatory polypeptide nanoparticles and a preparation method thereof, and belongs to the technical field of bioactive peptides. The anti-inflammatory polypeptide nano-particles are nano-particles obtained by coating polypeptide with an anti-inflammatory effect with chitosan and sodium tripolyphosphate, the polypeptide with the anti-inflammatory effect contains bioactive peptides of which the amino acid sequences are YAADQ, FPYTT and YVTYA. The phycocyanin anti-inflammatory peptide is natural in source, the performance of the phycocyanin anti-inflammatory peptide can be remarkably improved through the nanometer embedding technology, and compared with traditional drugs, the phycocyanin anti-inflammatory peptide has lower toxic and side effects and potential cost advantages. The polypeptide nanoparticles prepared by the invention can effectively prevent the phycocyanin anti-inflammatory peptide from being degraded in the digestive tract, have a remarkable treatment effect on mice with ulcerative colitis, and have an important application prospect in preparation of ulcerative colitis prevention and treatment products.
Owner:QINGDAO AGRI UNIV

Solid lipid nanoparticles for encapsulation and delivery of bioactive compounds and methods of making the same

Solid lipid nanoparticles (SLNs) for delivery of bioactive compounds are disclosed. The SLNs comprise a lipid matrix and surfactant layer encapsulating at least one bioactive compound selected from vitamins, minerals, enzymes, algae-derived bioactives, proteins, peptides, amino acids, antioxidants, small synthetic molecules, plant-derived volatile compounds, or botanical extracts. The SLNs exhibit submicron particle size, low polydispersity, and sufficient surface charge to ensure colloidal stability and efficient delivery. In one embodiment, algae-based bioactives, such as phycocyanin or fucoxanthin, are encapsulated using only natural and sustainable lipids and surfactants to improve bioavailability and support environmentally friendly formulations. The SLNs may be formulated for oral, topical, transdermal, injectable, ophthalmic, mucosal, textile, veterinary, or agricultural administration. Applications include human and animal health, functional foods, skincare, nutrient supplementation, and crop treatment. The disclosed SLNs offer a biocompatible and scalable delivery system that protects sensitive compounds, enables sustained release, and enhances absorption across diverse industries.
Owner:YUBECK INC

Pickering emulsion with stable phycocyanin-rosmarinic acid conjugate and application of Pickering emulsion in minced fillet products

The invention provides a Pickering emulsion with stable phycocyanin-rosmarinic acid conjugate and application of the Pickering emulsion in a surimi product, and the Pickering emulsion is characterized in that PC-Ra prepared by oxidizing rosmarinic acid with laccase and then covalently conjugating with phycocyanin is used as an emulsifier, corn oil is used as an oil phase, and five groups of emulsions from PC-Ra20 to PC-Ra40 are prepared through homogenization. The emulsion is added into surimi in proportion, and the surimi product is prepared through chopping and mixing, sausage filling and two-stage heating and can be used as a fat substitute to effectively fill and strengthen a gel three-dimensional network. Experiments show that the emulsion can overcome the gelation defect of the surimi caused by direct addition of grease, the PC-Ra30 group has the optimal effect, the gelation strength and the water binding capacity of the surimi can be remarkably improved, the cooking loss is reduced, and lipid is effectively delayed; according to the invention, bioactive components are combined with an emulsion technology, and an effective solution is provided for developing high-quality and high-added-value green surimi products.
Owner:HAINAN TROPICAL OCEAN UNIV

PHYCOCYANIN PURIFICATION PROCESS

ActiveMX434267BPectinaseAmylase
The present invention relates to a process for purifying phycocyanins from a solution comprising phycocyanins and glycogen, said phycocyanins being produced by microorganisms belonging to the order Cyanidiales, characterized in that it comprises (i) an enzymatic degradation step of glycogen with an enzyme suitable for degrading glycogen at a pH below 6 and a reaction temperature below 40°C, said enzyme being selected from a pectinase, a glucoamylase, or a mixture of a pectinase and a pullulanase, and (ii) a step of separating phycocyanins from the glycogen degradation products.
Owner:FERMENTALG

Lutein composition for relieving asthenopia and preparation method thereof

The invention discloses a lutein composition for relieving asthenopia and a preparation method of the lutein composition, and belongs to the field of functional foods. Phycocyanin and kelp polyphenol are mixed and react to obtain modified phycocyanin; fucoidin and beta-glucuronidase are mixed and react to obtain modified fucose; mixing the fish collagen peptide and zinc chloride to react to obtain a collagen peptide-zinc chelate; the xanthophyll siliceous cage compound and the modified phycocyanin are mixed and react to obtain a first compound; mixing and reacting the first compound and modified fucose to obtain a second compound; mixing and reacting the second compound, collagen peptide-zinc chelate and krill oil to obtain a lutein compound; mixing and reacting the second compound, collagen peptide-zinc chelate and krill oil, adding trehalose, and mixing and reacting to obtain a xanthophyll compound; and mixing the xanthophyll compound and maltodextrin to obtain the xanthophyll composition.
Owner:JIANGSU KEMA MEIBAO TECH CO LTD

A micellar system for improving the color stability of phycocyanin and a preparation method thereof

The application belongs to the technical field of food processing, and particularly relates to a method for improving color stability of phycocyanin by using a micellar system. The application provides a method for improving color stability of phycyanin by using a micellar system, so that the phycocyanin can maintain its blue color in a pasteurization process. The preparation method of the application is easy to apply, does not require complex or expensive equipment, is high in safety, and has a small additive amount and does not affect the original sensory properties of food. Not only the defect that the phycocyanin is easy to change and fade in color when heated in the production and processing process is solved, but also the technical problems of low action efficiency, low safety and difficulty in large-scale production in improving the thermal stability of phycocyanin are solved.
Owner:OCEAN UNIV OF CHINA

Zinc ion battery electrolyte containing phycocyanin as well as preparation method and application of zinc ion battery electrolyte

The invention discloses a zinc ion battery electrolyte containing phycocyanin as well as a preparation method and application of the zinc ion battery electrolyte. The zinc ion battery electrolyte is prepared from soluble zinc salt, phycocyanin and water, wherein the concentration of the phycocyanin is 0.1 mmol / L to 0.5 mmol / L; the concentration of the soluble zinc salt is 1 mol / L to 2 mol / L. In the zinc ion battery electrolyte disclosed by the invention, phycocyanin is a natural biomacromolecule which is natural, non-toxic, low in cost and environment-friendly, has various structures and is rich in various active functional groups, and the problems of high toxicity, single function, poor economic benefit and high cost of an organic additive in the prior art are solved. Besides, the zinc ion battery electrolyte can inhibit dendritic crystal growth, a stable interface layer is formed on the surface of a zinc negative electrode, side reactions are reduced, and the cycling stability and coulombic efficiency of the battery are improved.
Owner:JIANGXI NORMAL UNIV

Method for preparing characterization phycocyanin-zein-resveratrol compound

The invention belongs to the technical field of preparation and characterization of phycocyanin particle compounds, and particularly relates to a method for preparing and characterizing a phycocyanin-zein-resveratrol compound. The method is used for improving the light stability and the heat stability of phycocyanin. The preparation method of the compound comprises the following steps: step 1, accurately weighing 0.096 g of zein, dissolving the zein into 40 mL of 70% ethanol solution, and magnetically stirring for 30 minutes at 600 rpm; the preparation method comprises the following steps: respectively weighing 0.0192 g, 0.032 g and 0.096 g of resveratrol powder, adding the resveratrol powder into a zein solution, magnetically stirring in a dark place overnight at 600 rpm to obtain a zein-resveratrol solution, dissolving 0.096 g of phycocyanin powder into 120 mL of deionized water, magnetically stirring for 30 min at 600 rpm to obtain a phycocyanin solution, and adding the phycocyanin solution into the resveratrol solution to obtain the phycocyanin-resveratrol solution. The zein-resveratrol solution is injected into the phycocyanin solution by an injector, and the resveratrol in the compound can further improve the color stability of the phycocyanin in the illumination storage and heat treatment process.
Owner:JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE

Hemostatic and anti-infection bifunctional algal glue and preparation method thereof

The invention discloses haemostatic and anti-infection bifunctional algal glue and a preparation method thereof. The phycocolloid is prepared from phycocyanin, sodium alginate, polydopamine-piperidine nanoparticles, calcium chloride and water / ethanol. The preparation method comprises the following steps: reacting 2, 2, 6, 6-tetramethylpiperidine oxide with dopamine hydrochloride to prepare polydopamine-piperidine nanoparticles; the preparation method comprises the following steps: fully dissolving phycocyanin, sodium alginate and polydopamine-piperidine nanoparticles in a water / ethanol mixed solution; and adding an isometric calcium chloride aqueous solution, and stirring at room temperature to prepare the haemostatic and anti-infection bifunctional algal glue. The ratio of phycocyanin to sodium alginate is adjusted, the phycocyanin accounts for 1%-10% by weight, the sodium alginate accounts for 1%-5% by weight, different rheological properties and shape maintenance properties are obtained, the content of the nano polydopamine-piperidine compound is adjusted, the weight fraction is 0.1%-0.5%, the photo-thermal sterilization performance is obtained, and the photo-thermal sterilization effect is good. Therefore, the problem of repeated wound infection can be solved only through illumination.
Owner:HENAN INST OF SCI & TECH

Dual-mode mercury ion biosensor based on thermostable recombinant phycocyanin as well as preparation method and application of dual-mode mercury ion biosensor

The invention discloses a recombinant plasmid, a recombinant strain, recombinant phycocyanin and application of the recombinant plasmid, the recombinant strain and the recombinant phycocyanin in mercury ion detection. The invention further discloses a dual-mode mercury ion biosensor based on the thermal-stability recombinant phycocyanin and a preparation method and application of the dual-mode mercury ion biosensor. The biosensor based on the recombinant phycocyanin has specific fluorescence response to trace mercury ions. The recombinant phycocyanin pigment binding rate is higher than that of all reported recombinant phycocyanin, great Stokes shift (288 nm) is shown, the mercury ion selectivity is high, the thermal stability is good, the prepared biosensor shows the characteristics of dual-mode output and ultra-sensitive sensing, the detection limit under a fluorescence-based mode is 2.94 nM, and the biosensor has good application prospects. And the detection limit is 1.87 nM in a colorimetric mode based on fluorescence. The protein-based sensor is obtained from escherichia coli, is simple and convenient, supports in-situ monitoring of a smart phone, and is low in cost, excellent in performance and free of any toxicity.
Owner:NANJING FORESTRY UNIV

Phycocyanin conjugate targeting fibroblast, sol preparation and application of phycocyanin conjugate

The invention relates to the technical field of biological medicine, in particular to a fibroblast-targeting phycocyanin conjugate, a sol preparation and application of the fibroblast-targeting phycocyanin conjugate, phycocyanin and targeting peptide are covalently linked through an SMCC cross-linking agent, LDL receptor-associated protein 1 highly expressed by fibroblast is specifically recognized through the targeting peptide, and efficient intracellular delivery is achieved; a water-soluble sol preparation carries phycocyanin to break through a cell barrier, and LRP1-rich fibroblasts in a wound are targeted and play a role in the fibroblasts. By inhibiting the EMT process of fiber cells, cell fibrosis and growth of wound bacteria are inhibited, scar formation is reduced, and wound healing is promoted. The defect that natural phycocyanin cells are poor in penetrability is overcome, scar-free healing is achieved by regulating Wnt5a / beta-catenin through targeted delivery, the effect is good, and application and popularization are convenient.
Owner:THE WEST CHINA SECOND UNIV HOSPITAL OF SICHUAN

A microalgae-derived glyceroglycoside preparation, and a preparation method and application thereof

PendingCN122376604ACholesterolGlycerol
The present application provides a kind of microalgae source glycerol glucoside preparation and its preparation method and application, belong to medical technical field.The crude extract solution is obtained by low-osmotic extraction liquid extraction to salt stress algal mud, impurity is removed by filtration, and phycocyanin concentrated solution and glycerol glucoside containing permeate are obtained by membrane filtration separation, glycerol glucoside containing permeate is concentrated, bleaching and desalting, drying, and microalgae source glycerol glucoside is prepared, is mixed uniformly with gypenoside and bisabolol, and the mixture is prepared, after being embedded with oleic acid modified cholesterol and phospholipid to prepare modified liposome, mixed with chitosan solution and reacted, centrifuged, and the supernatant is discarded, and the solid is washed and dried to prepare microalgae source glycerol glucoside preparation.The present application realizes the technical effects of microalgae resource green low-carbon high-value utilization, product efficient purification, multi-target point synergistic anti-inflammatory and high transdermal absorption retention, and provides a kind of safe and effective, long-term use natural source new choice for treating atopic dermatitis externally.
Owner:青岛中科蓝智生物科技发展有限公司

Compositions for treating hair loss and hair graying

The present invention relates to a hair composition for use in the treatment and prevention of hair loss or grey hair. More specifically, the present invention relates to a composition comprising lutein and phycocyanin. The present invention relates in particular to the field of anti-hair loss and anti-grey products.
Owner:ALGAKTIV SL

Low-sodium salt containing phycocyanin and preparation method thereof

The invention provides phycocyanin-containing low-sodium salt and a preparation method thereof, and relates to the field of low-sodium salt. The preparation method of the phycocyanin-containing low-sodium salt comprises the following steps: pretreatment, preparation of a composite seed crystal dispersion liquid, and blending crystallization. According to the preparation method of the low-sodium salt containing phycocyanin, the phycocyanin and the low-sodium salt can be effectively combined, and the problem that the phycocyanin is easy to lose efficacy in the preparation of the low-sodium salt due to poor stability is effectively avoided; meanwhile, the problems that in the crystallization preparation process of the low-sodium salt, phycocyanin cannot be effectively and uniformly combined with the low-sodium salt crystals formed by growth, and the growth of the normal crystallization crystals of the low-sodium salt is influenced are further avoided.
Owner:SHANDONG SUSHA HIGH-TECH BIOTECHNOLOGY CO LTD

Method of culturing algae

The present invention relates to a heterotrophic methods of culturing algae, particularly Galdieria species, to produce the valuable pigment phycocyanin. The methods rely on high oxygen saturation and controlled base dosing to provide improved phycocyanin production. The present invention further relates to algal biomass, compositions comprising said biomass or phycocyanin, uses thereof in various products, and a reactor for culturing the algae.
Owner:UNIV OF SHEFFIELD

Separation and purification device for phycocyanin powder

The utility model relates to the technical field of phycocyanin powder production equipment, in particular to a phycocyanin powder separation and purification device which comprises a bearing frame, a purification mechanism and a collection mechanism, a fixed shell is fixedly connected to the bearing frame, a liquid outlet hole is formed in the fixed shell, a feeding pipe is fixedly connected to the fixed shell, the purification mechanism is arranged in the fixed shell, and the collection mechanism is arranged in the fixed shell. The collecting mechanism is arranged on the fixing shell. According to the phycocyanin purification device disclosed by the utility model, the purification mechanism is arranged in the fixed shell, an extracting solution is conveniently conveyed into the purification mechanism by virtue of the feeding pipe, the extracting solution is conveniently filtered by virtue of the filter membrane, and a phycocyanin solution is conveniently conveyed into the collection box by virtue of the conveying plate and the guide pipe; according to the phycocyanin filtering and concentrating device, the phycocyanin solution is filtered and concentrated, then a collecting box is used for storing the filtered and concentrated phycocyanin solution, a stepping motor I is started, so that a used filter membrane is convenient to replace, and when a communicating hole in which impurities are stored vertically faces downwards, the impurities conveniently fall into a conveying shell.
Owner:NINGXIA LENSI BIOTECHNOLOGY CO LTD

Oily food

PCT designated stageWO2026070427A1CocoaEdible oils/fatsBiotechnologyPhycocyanin
The present invention addresses the problem of providing an oily food having improved light resistance compared to conventional foods. An oily food according to the present invention meets all of the following requirements (A) to (C). (A) The oily food includes algae containing phycocyanin. (B) The oily food includes chlorophyll at a concentration of 6 mg / 100 g or more. (C) The oil-soluble chlorophyll content of the included chlorophyll is 15% to 80% by mass. However, the oil-soluble chlorophyll content refers to the ratio of the amount of chlorophyll dissolved in oil to the total amount of chlorophyll contained in the oily food.
Owner:FUJI OIL CO LTD

Formula composition containing phycocyanin peptide and application of formula composition in improvement of chronic obstructive pneumonia

The invention relates to a formula composition containing phycocyanin peptide and application of the formula composition in improvement of chronic obstructive pneumonia, and belongs to the field of functional formula food. The composition is prepared from the following components in parts by weight: 22.6 to 42.6 g of phycocyanin peptide, 10 to 30 g of fat, 27 to 47 g of carbohydrate, 1.0 to 2.0 g of vitamin, 1.1 to 4.1 g of mineral substances and 0.1 to 0.5 g of auxiliary materials. The formula food is balanced in nutrition, can supplement high-quality nitrogen (protein) for patients with chronic obstructive pulmonary diseases, can effectively improve symptoms of chronic obstructive pulmonary diseases and inflammatory response of organisms, and improves lung functions.
Owner:YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI +1

Method for extracting high-purity phycocyanin from spirulina

The invention relates to the technical field of bioactive substance extraction, in particular to a method for extracting high-purity phycocyanin from spirulina. The method comprises the following steps: (1) mixing spirulina powder with a phosphate buffer solution to obtain an algae suspension; (2) adding a compound enzyme into the algae suspension, and oscillating for enzymolysis to obtain enzymatic hydrolysate; the enzymatic hydrolysate is homogenized, and a homogenized solution is obtained; (3) centrifuging the homogenate, taking supernatant, filtering, and taking filtrate to obtain crude extract; (4) adding ammonium sulfate crystals into the crude extract, standing for 4-6 hours, centrifuging, taking precipitate, mixing the precipitate with a phosphate buffer solution, and performing ultrafiltration to obtain ultrafiltrate; and (5) enabling the ultrafiltrate to pass through a column, eluting, collecting a fraction of an A620 main peak, and freeze-drying to obtain phycocyanin. According to the method disclosed by the invention, high-purity phycocyanin can be extracted, and a basis is provided for efficient extraction of phycocyanin.
Owner:HEXI UNIV +1

Composition with auxiliary protection effect on chemical liver injury

PendingCN120713248AFood ingredient functionsEfficacyHepatocyte degeneration
The invention provides a composition. The composition is prepared from spleen aminopeptide, phycocyanin, folic acid substances and health-care food or medicine acceptable auxiliary materials. The composition disclosed by the invention has the advantages that the composition has a synergistic effect, can effectively reduce liver enzyme, improve degeneration and necrosis of liver cells and relieve chemical liver injury, has an immune regulation effect and can inhibit liver inflammatory response, so that the composition can be used for assisting in preventing and treating the chemical liver injury. In addition, the multi-component compound form of the product can obviously improve the taking compliance of users, and the total use cost is saved.
Owner:SHENZHEN AUSA PHARMA +1

Metal organic framework material, preparation method and application thereof

The application discloses a kind of metal organic framework material and its preparation method and application, wherein, preparation method includes the following preparation steps: zinc acetate, phycocyanin is dissolved in water, and mixed solution is prepared;Mixed solution is added to 2-methyl imidazole aqueous solution mixing stirring, centrifugation, and the precipitate is washed with water, dispersed in water, and nanoparticle dispersion is prepared;Nanoparticle dispersion, epigallocatechin gallate and manganese chloride are added to water mixing stirring, centrifugation, and the precipitate is washed with water, dispersed in water, and metal organic framework material is prepared.The metal organic framework material prepared by the application has free radical scavenging antioxidant capacity;It has anti-inflammatory effect, can reduce liver damage and necrosis, and is suitable for the treatment of acute liver injury;It also has the effects of regulating inflammatory response, promoting macrophage transformation and inhibiting T cell activation, and is suitable for immune regulation.
Owner:GUANGDONG PHARMA UNIV

Method for preparing high-purity phycocyanin by coupling supercritical extraction with aqueous two-phase extraction

The invention discloses a method for preparing high-purity phycocyanin by coupling supercritical extraction with aqueous two-phase extraction, which comprises the following steps: pretreatment of raw materials: pretreating spirulina powder, and centrifuging to obtain a phycocyanin crude extract; carrying out supercritical CO2 impurity removal: filling the phycocyanin crude extract obtained in the previous step into a supercritical extraction device, carrying out static extraction, and collecting an orange extract rich in carotenoid; then pumping ethanol as a carrying agent, carrying out dynamic extraction, and respectively collecting chlorophyll components and wet algae residues; and two-aqueous-phase extraction purification and post-treatment: purifying the treated wet algae residues by adopting a two-aqueous-phase extraction method, dialyzing by adopting a dialysis bag, and carrying out vacuum freeze drying to obtain a pure product. The phycocyanin distribution selectivity is remarkably improved, and the method is environmentally friendly and efficient; the time is shortened by about 93% compared with that of a traditional method, the phycocyanin purity is stable and is larger than or equal to 4.0, the production cost is greatly reduced, and the method is suitable for large-scale production.
Owner:SOUTH CHINA UNIV OF TECH

Application of C-phycocyanin and D-glucuronic acid in directly improving sperm motility in vitro and improving sperm motility after freezing recovery

The invention discloses application of C-phycocyanin and D-glucuronic acid in directly improving sperm motility in vitro and improving sperm motility after freezing recovery, and belongs to the technical field of biological medicine. According to the present invention, the mixed solution of D-glucuronic acid, C-phycocyanin, and D-phycocyanin has significant effects of in-vitro sperm motility promotion and sperm function protection, can be used for preparing the sperm motility improving drug or the sperm treatment reagent in the assisted reproduction technology, and has good application prospects.
Owner:SHANGHAI INST FOR BIOMEDICAL & PHARM TECH

Functional salt containing carrageenan, phycocyanin and beta-carotene, and preparation method therefor

PCT designated stageWO2026111029A1Food scienceSaline waterCarrageenan
The present invention relates to a functional salt containing beta-carotene, phycocyanin and carrageenan, and a method for preparing the functional salt. More specifically, the present invention relates to: a functional salt containing, as a functional ingredient, a Dunaliella culture cultured in high-salinity salty water or beta-carotene contained therein, phycocyanin isolated from a Spirulina culture, and carrageenan isolated from an extract of red algae; and a method for preparing the functional salt. The functional salt according to the present invention is an aqueous or powder-type functional salt, and contains beta-carotene, which is a functional ingredient derived from Dunaliella, phycocyanin, which is a functional ingredient derived from Spirulina, and carrageenan, which is a functional ingredient derived from red algae, and thus is beneficial to health, and, has low sodium content, and thus is a low sodium salt, thereby enabling side effects caused by excessive intake of salt to be prevented.
Owner:NPCGEN CO LTD