2213 results about "Hollow fibre" patented technology

A group of multiple hollow fibers may be shaped to introduce angular divergence among the fibers, or to introduce a selected longitudinal oscillation into the fibers. In one shaping technique, the fibers are held in parallel while upper and lower crimping assemblies of parallel crimping bars are drawn together on opposite sides of the parallel fibers. When bars of the opposing assemblies draw sufficiently close, they sandwich the fibers in between them, causing each fiber to assume a shape that oscillates as the fiber repeatedly goes over and then under successive bars. Since the crimping bars are aligned at oblique angles to the fibers, the peaks and troughs of successive fibers are offset. While in this position, the fibers are heated and then cooled to permanently retain their shapes. A different shaping technique utilizes a lattice of crisscrossing tines defining multiple apertures. In this technique, the lattice and fibers are positioned so that each fiber passes through one of the apertures. Then, the lattice and/or the fibers are slid apart or together until the lattice holds the fibers in a desired configuration, where the fibers have a prescribed outward divergence relative to each other. While in this position, the fibers are heated and then cooled to permanently retain this angular divergence.

The growth of continuous MOF membranes on porous polymeric supports is reported, wherein a dip-coating procedure is used to deposit a layer of seed MOF nanocrystals on the surfaces of porous polymers, preferably in the form of hollow fibers, and polycrystalline MOF membranes are subsequently grown at temperatures as low as 65° C. from precursor solutions. The present work opens the road to inexpensive and scalable fabrication of MOF membranes for large-scale separation applications.

Mixed matrix membranes are prepared from zeolites and polymers, such as polyimides, in a void free fashion where either no voids or voids of less than several Angstroms are present at the interface of the polymer and the zeolite by bonding (hydrogen, ionic, or covalent) functional groups on the zeolite with functional groups on the polymer. The mixed matrix membranes may be cast or formed by ISAM processes, and may be present on a variety of supports including hollow fibers.

Electrospinning of materials that are difficult or impossible to process into nanofibers by conventional fiber-forming techniques or by electrospinning are prepared by an electrospinning procedure which uses an electrospinnable outer “shell” fluid around an inner “core” fluid, which may or may not be electrospinnable, to form nanofibers of the inner core fluid having a core/shell morphology. The resulting shell around the nanofiber can remain in place or be removed during post-processing with the core of the fiber remaining intact. The dual-fluid electrospinning process can produce core fibers having diameters less than 100 nm, insulated nanowires, as well as tough, bio-compatible silk fibers. Alternatively, the core can be removed leaving a hollow fiber of the shell fluid.

A method for culturing cells, the method comprising: providing a plurality of cellulose hollow fibre capillaries having cells and at least one protein required for proliferation, differentiation and/or genetic modification of the cells therein and optionally at least one metabolite; and providing on the extracapillary side of the semi-permeable substrate at least one metabolite required for proliferation of the cells.

A membrane supported biofilm reactor uses modules having fine, hollow fibres, for example, made from dense wall Poly methylpentene (PMP) used in tows or formed into a fabric. In one module, one or more sheets of the fabric are potted into a module to enable oxygen containing gas to be supplied to the lumens of the hollow fibres. Various reactors and processes, for example to treat wastewater, using such modules are described. Mechanical, chemical and biological methods are used to control the thickness of the biofilm.

The invention relates to an enhanced graphene oxide hollow fiber composite membrane and a preparation method of the composite membrane. The composite membrane is characterized in that a supporting layer is a hollow pipe woven by polymer fibers, and a membrane separation layer on a surface is graphene oxide or a mixture of the graphene oxide and polymer resin; and the outer diameter of the hollow pipe woven by the polymer fibers is 1-4mm, and the inner diameter of the hollow pipe woven by the polymer fibers is 0.5-1mm; the thickness of the membrane separation layer is 0.01-1mm; and the membrane pore diameter of the enhanced graphene oxide hollow fiber composite membrane is 1-500nm. The preparation method comprises the following steps: dissolving the polymer resin, an organic additive, an inorganic additive and the graphene oxide into a organic solvent to prepare a membrane preparing solution; coating the membrane preparing solution onto the surface of the hollow pipe woven by the polymer fibers to obtain a blank body of a pre-fabricated composite membrane; and carrying out solidification and formation, rinsing and drying in the air to obtain the enhanced graphene oxide hollow fiber composite membrane. The prepared composite membrane is strong in hydrophilicity, and the water permeability of the composite membrane is greatly improved.

A novel cell seeded hollow fiber bioreactor is described as a potential bioartificial kidney. Endothelial cells along with pericyte, vascular smooth muscle, and/or mesangial cells or any mesenchymally derived support cells are seeded along a hollow fiber in a perfused bioreactor to reproduce the ultrafiltration function and transport function of the kidney. Maintenance of tissue specific function and ultrastructure suggest that this bioreactor provides an economical device for treating renal failure.

Devices and methods are described for pre-processing tissue samples containing cells of interest for various therapeutic procedures. Fibrous material may be extracted from the tissue sample through a shredding and separating device, resulting in a non-fibrous sample containing the cells of interest, which may then be washed and centrifuged to remove fluids, oil, and contaminants. The sample may then be digested in a large-volume container, and a piston within the container may push the resulting liberated cell suspension through a cell concentrator such as a hollow-fiber separation module.

Immersed hollow-fiber membrane filtration systems sometimes encounter process problems as a result of solids accumulation in and around the hollow fibers. The solids can accumulate to the point where they begin to dewater and form a mud like substance known as sludge. In some embodiments of the invention there is provided a process for substantially preventing the accumulation of sludge build-up on membrane fibers and/or cleansing membrane fibers that have been fouled by a substantial sludge build-up. Many of these embodiments involve aerating a membrane tank in which the membrane fibers are immersed after the water level has been reduced to near the level of solids accumulation. In some embodiments of the invention, the energy released by bursting bubbles at the liquid-air interface is employed to prevent fouling of membrane fibers and/or cleanse fouled membrane fibers.

The invention relates to a method for permeabilization of a cell structure consisting of a single cell, an intracellular structure or an organelle comprising the following steps: (a) microelectrodes, preferably two carbon fiber electrodes or hollow fiber electrodes, are provided, (b) the microelectrodes are connected to a power supply, (c) the electrodes, individually controlled by high-graduation micromanipulators, are placed close to the cell structure at an appropriate inter-electrode distance, and (d) a highly focused electric field of a strength sufficient to obtain electroporation is applied between the electrodes. The method may be used in order to transfer cell impermeant solutes, such as drugs or genes, into the cell structure or out of the cell structure, in biosensors, in the treatment of tumours and neurodegenerative diseases and in the study of biophysical processes.

The invention relates to a method for preparing hydrophilic PVDF microporous barrier. The principal raw material is polyvinylidene fluoride with the range of molecular weight: 5000 to 50000. It prepares hydrophilic PVDF microporous barrier by the method of separating solution and compounding dip-coating modification. It especially suits the occasion of effluent treatment, medicine separation and biochemy. The technology can prepare microporous barriers with plate type and hollow fiber type.

The invention discloses a hydrophilic polyvinylidene fluoride hollow fiber microporous membrane and the preparation method thereof. The main composition and the mass content of the membrane are 70% to 90% of polyvinylidene fluoride, amphiphilic poly-(propylene oxide-oxirane), 5% to 29% of poly-(methacrylic acid- acrylic acid) or poly-(methacrylic acid methyl ester-vinyl alcohol) copolymer and 1% to 5% of nano-silicon dioxide. The membrane preparation method is that all the components are mixed and dissolved with aperture regulator, thickener and solvent to obtain the membrane preparation liquid; after that, the hollow fiber forming is carried out through a dry-wet spinning technique, and finally cleaning and drying are implemented. The obtained membrane has adjustable internal diameter and external diameter, 60% to 80% of porosity and the aperture ranging from 0.01micron to 0.2micron. As a water disposal separating membrane material with excellent performance, the invention has the advantages of being able to be fully humid, organic adsorption resistance and great water flux, etc.

The invention relates to a method for producing ceramic hollow fibers from nanoscale particles and to hollow fibers produced in such a manner. The inventive method is characterized in that the ceramic material has a solids content of >25% by volume, preferably >30% by volume and is processed by means of extrusion and spinning. The hollow fiber is sintered according to conventional sintering methods. A hollow fiber produced in this manner is used for metal, polymer and ceramic matrix reinforcements, for artificial organs, for microsystems technology components, for fiber optical waveguides, for ceramic membranes, for solid electrolyte in fuel cells (SOFC), for tissue engineering and for producing extremely light ceramic parts, such as heat shields or brake systems, that are subjected to temperature stresses. The inventive ceramic batch can also be processed by means of silk screening whereby resulting in the production of filigree structures over the ceramic silk screening.

A filter for an extracorporeal blood circuit including a bundle of hollow fibers having an end section encased in a potting material, wherein the end section of potting material has an end surface with open ends of the fibers distributed throughout the end surface, and a filter header cap having an inlet connectable to a blood line and an open end sealed around a side surface of the end section of the bundle of hollow fibers.