This invention belongs to the field of
medical device technology and relates to an absorbable cardiac occluder flow-blocking membrane and its preparation method. The flow-blocking membrane is a multilayer
biodegradable polymer composite membrane structure, which sequentially includes: a first hydrophilic layer, a first
transition layer, a dense layer, a second
transition layer, and a second hydrophilic layer. The first hydrophilic layer, the first
transition layer, the second transition layer, and the second hydrophilic layer are all loose and porous layered structures, while the dense layer is a dense
layered structure. The first and second hydrophilic
layers are made of
natural polymers, the first and second transition
layers are made of a mixture of natural and synthetic polymers, and the dense layer is made of synthetic polymers. This absorbable cardiac occluder flow-blocking membrane has good hydrophilicity, anti-inflammatory properties, and mechanical properties, which can effectively accelerate endothelialization and reduce post-implantation inflammatory responses, thus enabling its application in cardiac occluders.