6745results about "Absorbent pads" patented technology

The invention relates to the field of disposable hygienic products, in particular to a high-diffusion baby paper diaper and a preparation method thereof.The prepared baby paper diaper has the advantages of being good in flow guide effect and high in absorption efficiency. The absorption core layer comprises a top layer non-woven fabric, a middle non-woven fabric, a bulky non-woven fabric, a bottom layer non-woven fabric, a wood pulp fiber layer, a first absorption material layer and a second absorption material layer, the first absorption material layer comprises first polymer water-absorbent resin particles and first wood pulp fibers, and the second absorption material layer comprises second polymer water-absorbent resin particles. The second absorbing material layer is arranged between the bulky non-woven fabric and the bottom layer non-woven fabric, part of the second macromolecule water-absorbent resin particles on the second absorbing material layer are embedded in pores of the bulky non-woven fabric, and the first absorbing material layer is arranged between the bulky non-woven fabric and the middle non-woven fabric. And a part of the first high-molecular water-absorbent resin particles on the first absorbing material layer are embedded in pores of the bulky non-woven fabric.

The invention discloses an antibacterial peptide and application thereof, and belongs to the technical field of biology. The antibacterial peptide with an inhibition effect on various clinically common pathogenic microorganisms is obtained, and the antibacterial peptide comprises gram-negative bacteria such as escherichia coli, klebsiella pneumoniae, pseudomonas aeruginosa, acinetobacter baumannii, vibrio parahaemolyticus, salmonella gallinarum, salmonella typhimurium and enterobacter sakazakii, and gram-positive bacteria. The antibacterial peptide provided by the invention can be used as an antibacterial peptide, such as staphylococcus aureus, listeria monocytogenes and bacillus cereus, and the antibacterial peptide provided by the invention is novel in structure and easy to prepare.

An absorbent article comprising a hotmelt adhesive comprising a styrene-block-copolymer (SBC), an amorphous polyolefin and optionally a tackifier. The SBC is preferably selected from the group of SEBS, SEPS and SEP polymers, and the amorphous polyolefin is preferably a propylene-based copolymer (PbP) having a weight-average molecular weight Mw of less than 10 000 g / mol. The hotmelt adhesive bonds two components of the article, for example SAP particles on the core wrap.

The invention discloses a Janus wound dressing with antibacterial and tissue repair promoting functions and a preparation method of the Janus wound dressing, belongs to the technical field of wound dressings, and aims to realize antibacterial, tissue repair promoting and moist wound healing microenvironment through freeze drying and electrostatic spinning technologies. Polycaprolactone (PCL), bioactive glass (BG) and curcumin Cur are used for preparing a hydrophobic inner layer capable of promoting tissue repair, methacrylated gelatin GelMA is used for preparing a hydrophilic outer layer with moisturizing performance, and the PCL-BG-Cur / GelMA composite wound dressing with antibacterial, moisturizing and repair promoting functions is constructed. Animal experiment results show that the dressing loaded with curcumin Cur and bioactive glass BG has multiple functions of synergistic antibiosis, moisturizing and the like, the result shows that the prepared dressing has the performance of promoting epithelization, collagen deposition, new hair follicle formation and the like, and the dressing has a considerable application prospect in the aspect of rapid wound repair.

The invention belongs to the field of biological materials, and particularly relates to recombinant V-type humanized collagen and application thereof. The invention provides a recombinant V-type humanized collagen, the amino acid sequence of the recombinant V-type humanized collagen comprises (repetitive unit) n, and the repetitive unit comprises a sequence as shown in SEQ ID NO.1; each repeating unit is directly linked and the number n of repeating units is 10. The recombinant V-type humanized collagen can comprehensively resist skin aging.

The present disclosure relates to absorbent articles including elastic laminates and to methods and apparatuses for making absorbent articles having elastic laminates in front and / or back waist regions with frangible pathways.

The present disclosure relates to diaper pants having a first belt and a second belt with one or more frangible pathways. A frangible pathway may extend between inner edge and outer edges of a belt. A grip region comprising an accessibility opening may be positioned between the inner and outer edges of the belt. The frangible pathway may comprise a first tear zone and a second tear zone extending from the accessibility opening to a distal terminus and to a proximal terminus. Such frangible pathway configurations provide a feature that allows a belt of a diaper pant to be relatively easily torn along the frangible pathway. Once torn along the frangible pathway, the diaper pant may be removed from a wearer and rolled up for disposal. A fastener component may be connected with another portion of the diaper pant to help maintain the diaper pant in a disposal configuration.

The invention relates to the technical field of medical materials, and particularly discloses a biocompatible hydrogel microneedle nursing dressing and a preparation method thereof. A biocompatible hydrogel microneedle nursing dressing comprises a hydrogel substrate, microneedles regularly attached to the side, facing the skin, of the hydrogel substrate, and a breathable film layer attached to the side, back to the skin, of the hydrogel substrate. The micro-needle array tip area of the biocompatible hydrogel micro-needle nursing dressing provides rigid support through silk fibroin, it is ensured that a micro-needle can penetrate through the cuticle, the silk fibroin and hyaluronic acid are compounded through the middle-layer needle body transition area, the mechanical strength and the swelling property are balanced, the flexibility is improved through glycerinum, the needle body is prevented from being broken, and the biocompatibility is improved. The closed area of the top substrate adopts high-concentration hyaluronic acid to achieve rapid water absorption swelling and promote drug diffusion, polydopamine nanoparticles enhance antibacterial property and tissue adhesion, genipin crosslinking improves mechanical strength, and a sealing barrier is formed to prevent drug leakage.

The invention relates to the technical field of medical dressings, in particular to a perianal drug dressing of a multi-layer flow guide composite fabric and a preparation method and application of the perianal drug dressing of the multi-layer flow guide composite fabric. The perianal drug dressing is of a four-layer structure, a wet tissue adhesion layer is made of polydopamine modified chitosan / oxidized hyaluronic acid hydrogel, and wet-state adhesion is achieved; the drug sustained-release layer is used for dispersing mesoporous silica loaded with ciprofloxacin hydrochloride / defensin and chitosan microspheres loaded with epidermal growth factors / lonicera japonica into a polycaprolactone fiber membrane to achieve synergistic antibacterial and healing promotion; the directional flow guide layer is of a gradient wettability sandwich structure with a bionic micro-channel, and one-way rapid drainage can be achieved; the high-absorption outer layer is carboxymethyl cellulose / sodium polyacrylate composite sponge, liquid is locked efficiently, the wound surface is kept dry and comfortable, the clinical problem in perianal infection wound treatment can be effectively solved, and the treatment effect and the patient comfort are remarkably improved.

The invention provides a recombinant humanized elastin with high biological activity as well as a preparation method and application thereof, and belongs to the technical field of genetic engineering and biological materials. 100% of the amino acid sequence of the elastin is derived from human elastin and is prepared by expression of genetically engineered bacteria; the protein has a typical beta-spiral hydrophobic structural domain and a lysine-rich hydrophilic structural domain, has a good bionic structure and functional characteristics, can significantly promote proliferation, adhesion and migration of human skin fibroblasts, also has excellent antioxidant, anti-wrinkle and anti-aging activities, and can be used for preparing a biomimetic protein. The hydrogel can be widely applied to the fields of skin repair dressings, injection implants, artificial skin, biomedical materials, functional skin care products and the like; in addition, the elastin is good in solubility, high in stability, mature in expression system and suitable for large-scale production.

The invention relates to the technical field of microorganisms, and provides lactobacillus crispatus FMTA1145 C with a bacteriostatic effect and application of the lactobacillus crispatus FMTA1145 C. The lactobacillus crispatus FMTA1145 C is preserved in the China General Microbiological Culture Collection Center (CGMCC) on April 22, 2025, the address of the lactobacillus crispatus FMTA1145 C is No.3, No.1 yard, Beichen West Road, Chaoyang District, Beijing, and the preservation number of the lactobacillus crispatus FMTA1145 C is CGMCC NO.34293. The lactobacillus crispatus FMTA1145 C has the advantages that the lactobacillus crispatus FMTA1145 C has the antibacterial effect, and the lactobacillus crispatus FMTA1145 C has been preserved in the China General Microbiological Culture Collection Center (CGMCC) on April 22, 2025; according to the technical scheme, the problem that the existing lactobacillus crispatus has a poor treatment effect on female vaginal diseases in the prior art is solved.

The present disclosure relates to absorbent articles including elastic laminates, and more particularly, to methods and apparatuses for making absorbent articles having elastic laminates in front and / or back waist regions with frangible pathways.

The invention relates to a double-layer dressing for promoting wound healing and inhibiting scars and a preparation method and application thereof.The double-layer dressing comprises a hydrogel layer and a piezoelectric film layer compounded on the hydrogel layer, and the piezoelectric film layer is prepared by mixing an organic piezoelectric material, a ferroelectric material and an organic solvent and then conducting an electrostatic spinning technology; the hydrogel layer is formed by curing a methacrylic anhydride acellular extracellular matrix, methacrylic anhydride catechol chitosan and conductive nanoparticles under the action of a curing agent. The lower skin contact layer of the double-layer dressing is the hydrogel layer, so that the directional growth of fibroblasts is favorably induced; the upper dressing is a piezoelectric material composite ferroelectric material, is beneficial to piezoelectric stimulation re-induction function recovery after final skin repair and guidance of directional growth of wound cells, and has good skin wound induction repair and scar inhibition effects.

The invention belongs to the technical field of battery dressings, and particularly relates to a wearable magnesium battery self-powered dressing for chronic wound healing and a preparation method and application thereof. A flexible conductive carbon cloth coated with a viologen-based covalent organic framework material is used as a battery positive electrode, a magnesium sheet is used as a negative electrode, polyacrylamide hydrogel is used as a solid electrolyte, and the flexible wearable self-powered dressing is assembled. The formed electrode can effectively input electrical stimulation to the wound surface, the dressing can simulate an endogenous electric field in the wound, induce migration of fibroblasts, regulate the immune microenvironment of the wound and inhibit inflammatory response, polyacrylamide is used as gel electrolyte, and the dressing has good hygroscopicity, can absorb exudate at the wound surface and keep a wet healing environment, and can be applied to the wound healing. The chronic wound healing of the rat is effectively promoted. The self-powered dressing prepared by the invention provides a reliable electrotherapy method for chronic wound healing.

Sheets of material used in medical devices and filters are disclosed. The sheets may include a fibrous mat including a plurality of microfibers. The microfibers may include a polymer matrix and a plurality of additive particles. The additive particles may include carbon material particles, therapeutic micro particles, and any combination thereof. Medical devices and filters that use the sheets are disclosed. Methods of producing the sheets are also disclosed.

The invention discloses a photo-thermal composite hydrogel patch and a preparation method and application thereof.The hydrogel patch is of a three-dimensional latticed porous structure formed by taking methylacryloyl gelatin (GelMA) and methylacryloyl hyaluronic acid (HAMA) as matrixes, loading niobium carbide nano-particles (Nb2CNPs) and vinipofen (VP) and conducting 3D printing or casting molding, the hydrogel patch is named as VP-Nb2C-coated GelMA / HAMA (VNGH) hydrogel patch for short. The VNGH has good photo-thermal antibacterial property, oxidation resistance and reepithelization promoting function, can significantly improve the quality of mouse diabetic wound healing, and provides a new thought and strategy for realizing scar-free healing of diabetic wounds.

The invention relates to the technical field of bioengineering, in particular to a recombinant VII type collagen for inhibiting scars as well as a preparation method and application of the recombinant VII type collagen. The amino acid sequence of the recombinant VII type collagen is as shown in SEQ ID NO. 1. The recombinant VII type collagen provided by the invention has a better cell adhesion function, so that the recombinant VII type collagen can be applied to the fields of preparation of tissue materials, wound dressings and the like. Meanwhile, the VII type collagen does not contain any tag or exogenous amino acid sequence, is a completely humanized sequence, and does not generate immune response. The VII type collagen has a good adhesion effect, the adhesion effect is better than that of other recombinant collagen, the adhesion effect is equivalent to that of a common cell adhesive in the market, scars can be reduced by inhibiting activation of a TGF-beta pathway, and the VII type collagen can be developed into skin care products and medical instruments for promoting traceless wound repair and has a wide application prospect.

A process and system for producing nonwoven substrates are disclosed. Also disclosed is a forming surface or forming wire for producing the substrates. The forming surface includes a pattern of high porosity zones and low porosity zones. The low porosity zones have a non-zero but low porosity. A wet suspension of fibers is deposited onto the forming surface to form nonwoven substrates having areas of high basis weight and low basis weight. The low porosity zones have a width dimension that is greater than the average fiber length of at least some of the types of fibers contained in the fiber furnish to form substrates having exceptional properties, especially with respect to fluid control properties.

The present disclosure relates generally to antimicrobial gels. In particular, the present disclosure relates to an antimicrobial gel comprising a eutectic solvent and a gelling agent which can be used as a drug delivery vehicle for antimicrobial agents, including for the topical delivery of antimicrobial agents to the skin of a subject. The present disclosure also relates to processes for preparing the antimicrobial gel, and to methods, uses and compositions comprising the antimicrobial gel.

The present invention relates to the field of biomedical materials, particularly to a novel composite collagen material for wound repair, and more specifically to a method for preparing a novel composite collagen material comprising recombinant humanized collagen type 21 (ColpepA1 21) and its use in wound repair. The present invention utilizes ColpepA1 21 to significantly promote key biological reactions in the wound healing process, including accelerating cell migration, enhancing skin hydration and barrier function, and improving the stability and elasticity of skin structure. The resulting novel composite collagen material effectively promotes wound healing and cell regeneration, alleviating oxidative damage.

An assembly having a chassis, two supports with a plate and a guide, a nesting system with a bore, a reservoir containing an extinguishing fluid and with two fastening tabs, two bearing tabs and a peg, and a fastener. The reservoir is able to move in translation between a premounting position in which each fastening and bearing tab rests on a plate and each guide guides the fastening and bearing tabs to align the peg and the bore, and a mounting position in which each fastening tab rests on the plate, the peg is introduced into the bore, the bearing tabs no longer rest on the plates and the fastener fastens each fastening tab to the plate. Such an assembly allows the reservoir to be withdrawn and put in place quickly and easily.

The invention provides a preparation method of super absorbent resin, and relates to the technical field of super absorbent resin. The preparation method comprises the following steps: diluting acrylic acid with water, and adding alkali liquor for neutralization to obtain a neutralized solution; mixing an emulsifying agent, a thickening agent and foaming carbonate to obtain a foaming promoting auxiliary agent; adding a cross-linking agent, a photoinitiator and a temperature initiator into the neutralization solution to obtain a polymerization mother solution; uniformly mixing a foaming promoting auxiliary agent with the polymerization mother liquor, and initiating polymerization of the polymerization mother liquor under a UV illumination condition to obtain acrylate polymer gel; drying the acrylate polymer gel, and crushing and screening to obtain basic particles; and spraying a surface cross-linking treatment liquid on the surfaces of the basic particles, initiating a surface cross-linking reaction of the basic particles through heat treatment, and adding an inert filler after the surface cross-linking reaction to prepare the super absorbent resin finished product particles. The super absorbent resin disclosed by the invention has the characteristics of high reaction efficiency, high liquid absorption speed, good liquid passing performance, excellent reverse osmosis resistance and the like.

The invention provides a soybean amyloid protein fiber, a preparation method thereof, a high internal phase emulsion and application, and belongs to the technical field of protein fibers. The preparation method comprises the following steps: dissolving soybean protein isolate in water, adjusting the obtained soybean protein isolate solution to a first pH value, carrying out ultrasonic treatment and / or first stirring treatment, adjusting the obtained feed liquid to a second pH value, sequentially carrying out second stirring treatment, dialysis and freeze drying, and dissolving the obtained pretreated soybean protein isolate in water, adjusting the pH value of the pretreated soybean protein isolate solution to a third pH value, and sequentially performing hydration treatment and fiber growth treatment to obtain the soybean amyloid protein fiber. The invention provides a soybean amyloid protein fiber preparation method based on ultrasonic pretreatment and / or pH migration pretreatment. The yield and the emulsifying property of the obtained soybean amyloid protein fiber can be remarkably improved.

The invention relates to the technical field of baby diapers, in particular to an intelligent baby diaper replacement reminding system integrated with hydrogen sulfide detection, which is used for determining a reference acquisition frequency of each time interval in a time period based on historical multi-dimensional monitoring data of a target user; then determining the necessity of hydrogen sulfide detection at the current acquisition moment based on the multi-dimensional monitoring data in the backtracking time window at the current acquisition moment, and then adjusting the reference acquisition frequency of the current time interval based on the necessity of hydrogen sulfide detection at the current acquisition moment to obtain a final acquisition frequency; acquiring multi-dimensional monitoring data based on the final acquisition frequency in the remaining time interval in the current time interval; and finally, based on the multi-dimensional monitoring data acquired in real time, generating a diaper replacement reminding signal.

The invention discloses a quick-absorption type adult paper diaper and a preparation method thereof, and relates to the field of hygienic products, the quick-absorption type adult paper diaper comprises a surface layer, a flow guide layer, an absorption core layer and a leakage-proof bottom film which are arranged in sequence, the absorption core layer comprises an upper layer non-woven fabric, a first liquid absorption layer, deodorization fibers, a second liquid absorption layer and a lower layer non-woven fabric which are stacked in sequence, the first liquid absorption layer and the second liquid absorption layer are formed by mixing SAP and fluff pulp according to the mass ratio of (40-70): (30-60), and the SAP is prepared from the following raw materials in parts by weight: 100-120 parts of acrylic acid; 70-90 parts of a 30% sodium hydroxide solution; 4-8 parts of polyvinyl alcohol sodium sulfate; 10 to 14 parts of starch; 2-4 parts of an initiator; 0.5 to 1 part of a cross-linking agent; and 180 to 220 parts of deionized water. The liquid absorption performance and the deodorization and antibacterial performance of the absorption core layer of the adult paper diaper can be improved.

The invention discloses a recombinant silk fibroin fusion protein as well as a preparation method and application thereof. The amino acid sequence of the recombinant silk fibroin is as shown in SEQ ID NO: 3. According to the invention, the silk fibroin is efficiently expressed through a genetic engineering method, and the recombinant silk fibroin or the recombinant silk fibroin which is high in expression and purity and can retain the efficacy and the activity of natural protein is finally obtained, so that the recombinant silk fibroin or the recombinant silk fibroin has relatively high industrial application potential.

The device comprises a pre-stretching elastic film layer which is sequentially stacked, a gradient drainage layer is arranged below the pre-stretching elastic film layer, and sealing edges are arranged on the outer edges of the pre-stretching elastic film layer and the gradient drainage layer. The sealing edge surrounds the edges of the pre-stretching elastic film layer and the gradient drainage layer and is used for being bonded with the skin to form a closed cavity. Continuous negative pressure is provided through retraction force of the pre-stretched elastic thin film layer, compared with a traditional external pump, the cost is lower, use is more convenient, adhesion with a postoperative wound part is prevented through the arrangement of the anti-adhesion contact layer, and the postoperative wound part is prevented from being damaged. And meanwhile, the anti-adhesion contact layer is provided with a micron-sized bulge array and nano-sized surface textures, so that the anti-adhesion effect is further ensured, and the drainage efficiency is improved through the design of the gradient drainage layer.

The present invention concerns extensible absorbent pads for wound dressings. The absorbent pad has a plurality of fenestrations therein, wherein the fenestrations are arranged in a pattern about a central point. The pattern comprises one or more fenestrations having symmetry about a cardinal axis and one or more fenestrations having symmetry about an intercardinal axis, wherein the cardinal and intercardinal axes cross at the central point. The absorbent pads of the present invention can be used in advanced wound care dressing applications where additional stretch and extensibility of the dressing will assist clinicians in applying the dressing to difficult to dress anatomical areas.

The present invention discloses a strain of Lactobacillus paracasei that simultaneously activates immune regulation and antioxidant pathways to alleviate vaginitis, belonging to the field of microbial technology. The present invention screened and obtained a strain of Lactobacillus paracasei CCFM1316, which has the effect of repairing related symptoms such as immune disorders and oxidative damage caused by vaginitis, specifically embodied in: reducing cellular NF-κB mRNA expression and cell supernatant IL-1β content, improving mouse vaginal immune response, enhancing mouse vaginal antioxidant capacity, improving mouse vaginal pathological manifestations and reducing pathogenic bacteria load. It reduces the mouse vaginal Gardnerella load and improves mouse vaginal pathological manifestations; therefore, Lactobacillus paracasei CCFM1316 has great application prospects in products that improve and repair immune disorders and oxidative damage problems caused by vaginitis.