4480results about "Absorbent pads" patented technology

The invention belongs to the field of biological materials, and particularly relates to recombinant V-type humanized collagen and application thereof. The invention provides a recombinant V-type humanized collagen, the amino acid sequence of the recombinant V-type humanized collagen comprises (repetitive unit) n, and the repetitive unit comprises a sequence as shown in SEQ ID NO.1; each repeating unit is directly linked and the number n of repeating units is 10. The recombinant V-type humanized collagen can comprehensively resist skin aging.

The present disclosure relates to absorbent articles including elastic laminates and to methods and apparatuses for making absorbent articles having elastic laminates in front and / or back waist regions with frangible pathways.

The present disclosure relates to diaper pants having a first belt and a second belt with one or more frangible pathways. A frangible pathway may extend between inner edge and outer edges of a belt. A grip region comprising an accessibility opening may be positioned between the inner and outer edges of the belt. The frangible pathway may comprise a first tear zone and a second tear zone extending from the accessibility opening to a distal terminus and to a proximal terminus. Such frangible pathway configurations provide a feature that allows a belt of a diaper pant to be relatively easily torn along the frangible pathway. Once torn along the frangible pathway, the diaper pant may be removed from a wearer and rolled up for disposal. A fastener component may be connected with another portion of the diaper pant to help maintain the diaper pant in a disposal configuration.

The invention relates to the technical field of medical dressings, in particular to a perianal drug dressing of a multi-layer flow guide composite fabric and a preparation method and application of the perianal drug dressing of the multi-layer flow guide composite fabric. The perianal drug dressing is of a four-layer structure, a wet tissue adhesion layer is made of polydopamine modified chitosan / oxidized hyaluronic acid hydrogel, and wet-state adhesion is achieved; the drug sustained-release layer is used for dispersing mesoporous silica loaded with ciprofloxacin hydrochloride / defensin and chitosan microspheres loaded with epidermal growth factors / lonicera japonica into a polycaprolactone fiber membrane to achieve synergistic antibacterial and healing promotion; the directional flow guide layer is of a gradient wettability sandwich structure with a bionic micro-channel, and one-way rapid drainage can be achieved; the high-absorption outer layer is carboxymethyl cellulose / sodium polyacrylate composite sponge, liquid is locked efficiently, the wound surface is kept dry and comfortable, the clinical problem in perianal infection wound treatment can be effectively solved, and the treatment effect and the patient comfort are remarkably improved.

The present disclosure relates to absorbent articles including elastic laminates, and more particularly, to methods and apparatuses for making absorbent articles having elastic laminates in front and / or back waist regions with frangible pathways.

Sheets of material used in medical devices and filters are disclosed. The sheets may include a fibrous mat including a plurality of microfibers. The microfibers may include a polymer matrix and a plurality of additive particles. The additive particles may include carbon material particles, therapeutic micro particles, and any combination thereof. Medical devices and filters that use the sheets are disclosed. Methods of producing the sheets are also disclosed.

The invention relates to the technical field of bioengineering, in particular to a recombinant VII type collagen for inhibiting scars as well as a preparation method and application of the recombinant VII type collagen. The amino acid sequence of the recombinant VII type collagen is as shown in SEQ ID NO. 1. The recombinant VII type collagen provided by the invention has a better cell adhesion function, so that the recombinant VII type collagen can be applied to the fields of preparation of tissue materials, wound dressings and the like. Meanwhile, the VII type collagen does not contain any tag or exogenous amino acid sequence, is a completely humanized sequence, and does not generate immune response. The VII type collagen has a good adhesion effect, the adhesion effect is better than that of other recombinant collagen, the adhesion effect is equivalent to that of a common cell adhesive in the market, scars can be reduced by inhibiting activation of a TGF-beta pathway, and the VII type collagen can be developed into skin care products and medical instruments for promoting traceless wound repair and has a wide application prospect.

A process and system for producing nonwoven substrates are disclosed. Also disclosed is a forming surface or forming wire for producing the substrates. The forming surface includes a pattern of high porosity zones and low porosity zones. The low porosity zones have a non-zero but low porosity. A wet suspension of fibers is deposited onto the forming surface to form nonwoven substrates having areas of high basis weight and low basis weight. The low porosity zones have a width dimension that is greater than the average fiber length of at least some of the types of fibers contained in the fiber furnish to form substrates having exceptional properties, especially with respect to fluid control properties.

The present disclosure relates generally to antimicrobial gels. In particular, the present disclosure relates to an antimicrobial gel comprising a eutectic solvent and a gelling agent which can be used as a drug delivery vehicle for antimicrobial agents, including for the topical delivery of antimicrobial agents to the skin of a subject. The present disclosure also relates to processes for preparing the antimicrobial gel, and to methods, uses and compositions comprising the antimicrobial gel.

The invention relates to the technical field of baby diapers, in particular to an intelligent baby diaper replacement reminding system integrated with hydrogen sulfide detection, which is used for determining a reference acquisition frequency of each time interval in a time period based on historical multi-dimensional monitoring data of a target user; then determining the necessity of hydrogen sulfide detection at the current acquisition moment based on the multi-dimensional monitoring data in the backtracking time window at the current acquisition moment, and then adjusting the reference acquisition frequency of the current time interval based on the necessity of hydrogen sulfide detection at the current acquisition moment to obtain a final acquisition frequency; acquiring multi-dimensional monitoring data based on the final acquisition frequency in the remaining time interval in the current time interval; and finally, based on the multi-dimensional monitoring data acquired in real time, generating a diaper replacement reminding signal.

The present invention concerns extensible absorbent pads for wound dressings. The absorbent pad has a plurality of fenestrations therein, wherein the fenestrations are arranged in a pattern about a central point. The pattern comprises one or more fenestrations having symmetry about a cardinal axis and one or more fenestrations having symmetry about an intercardinal axis, wherein the cardinal and intercardinal axes cross at the central point. The absorbent pads of the present invention can be used in advanced wound care dressing applications where additional stretch and extensibility of the dressing will assist clinicians in applying the dressing to difficult to dress anatomical areas.

Novel compositions and systems for closure of wounds with antimicrobial effectiveness are disclosed. The compositions provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. The present invention is also directed to a novel platinum catalyst for use in such compositions. The catalyst provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2-5 minutes.

The invention provides a wound dressing for diminishing inflammation, easing pain and promoting wound healing and a preparation method thereof. The wound dressing capable of diminishing inflammation, easing pain and promoting wound healing is prepared from the following components in parts by mass: 6 to 10 parts of oxidized sodium alginate, 7 to 9 parts of hydrazide gelatin, 1 to 1.5 parts of tannic acid, 8 to 12 parts of polyethylene glycol, 0.05 to 0.1 part of cannabidiol, 0.05 to 0.1 part of neomycin sulfate, 0.2 to 0.3 part of 2-roots alcohol, 0.02 to 0.04 part of vitamin C palmitate and 0.03 to 0.1 part of epsilon-polylysine. The dressing can achieve excellent effects of diminishing inflammation, easing pain and promoting wound healing through synergistic cooperation of all the components.

The present disclosure relates to absorbent articles having a first belt and a second belt with one or more frangible pathways. A frangible pathway may extend between a proximal terminus on an inner edge of a belt and a distal terminus on an outer edge of the belt. A grip region comprising an accessibility opening may be positioned between the inner and outer edges of the belt. The frangible pathway may comprise a first tear zone and a second tear zone extending from the accessibility opening to the distal terminus and to the proximal terminus. Such frangible pathway configurations provide a feature that allows a belt of a diaper pant to be relatively easily torn along the frangible pathway when removing the diaper pant from a wearer. The frangible pathway may be configured to allow a caregiver to initiate and / or completely tear the first belt with one hand.

The invention discloses an antibacterial breathable dressing patch and a preparation method thereof, and belongs to the field of medical dressings, the antibacterial breathable dressing patch comprises a Janus type dressing patch layer which is a composite film containing a hydrocolloid matrix, pH response antibacterial microspheres and bioactive glass nanoparticles; the super-hydrophobic electrostatic spinning outer layer is a super-hydrophobic electrostatic spinning fiber membrane, and the super-hydrophobic electrostatic spinning outer layer and the Janus type dressing skin-attaching layer are compounded to form an asymmetric Janus structure, intellectualization and precision of the antibacterial effect are achieved, and the risks of cytotoxicity and bacterial drug resistance possibly caused by long-term exposure to an antibacterial agent are reduced to the maximum extent; a multi-mechanism and synergistic antibacterial defense system is constructed, more comprehensive and firm protection is provided for wounds, the air permeability and moisture permeability are excellent, a dry and moist ideal healing environment is created for the wounds, the biocompatibility is good, the use safety is high, the wound healing agent is mild to human tissues, the irritation is low, the allergic reaction risk is small, the safety is high, and the wound healing effect is good. The long-term use is facilitated.

The present invention relates to the technical field of protein engineering and provides a recombinant humanized type III collagen having a triple helix structure, a preparation method therefor, and a use thereof. The amino acid sequence of the recombinant humanized type III collagen comprises n core units, wherein n is 1 or an integer greater than 1, and the amino acid sequence of the core unit is as shown in SEQ ID NO: 1. The present invention further provides a method for constructing an expression system and a method for preparing a recombinant humanized type III collagen. The present invention further provides an actual industrial use on the basis of the characteristics of the protein. The recombinant humanized type III collagen provided by the present invention has high purity, good stability, and high biological activity. Experiments have shown that the recombinant humanized type III collagen has various biological activities such as promoting cell proliferation and migration.

The invention discloses an antibacterial dressing for skin repair and a preparation method thereof, and relates to the field of medical dressings. The antibacterial dressing for skin repair is prepared from the following raw materials in parts by weight: 4-8 parts of carboxymethyl chitosan, 2-5 parts of collagen, 5-10 parts of glycerol, 10-20 parts of a framework material, 1-2 parts of an antibacterial agent, 1-3 parts of a humectant and 70 parts of purified water. The prepared antibacterial dressing for skin repair has good moisturizing performance and antibacterial performance.

The invention discloses a polylipoic acid-based composite sponge wound dressing and a preparation method and application thereof.The preparation method comprises the following steps that polylipoic acid amide with amino is obtained through disulfide bond ring opening polymerization, and the polylipoic acid amide and an aldehyde cross-linking agent are jointly dissolved in ethyl alcohol to form a solution A; carrying out high-speed shearing, dispersing and foaming on the water-soluble polymer, and freeze-drying to form porous sponge B; the porous sponge B is soaked in the solution A to be subjected to a cross-linking reaction, vacuum drying is conducted, and the polylipoic acid-based composite sponge wound dressing is obtained. The preparation method has the characteristics of simple preparation process, safety and no toxicity, the polylipoic acid with excellent oxidation resistance is introduced into the medical sponge material, the preparation method of the polylipoic acid medical porous structure material is obtained, the oxidation resistance and the wet viscosity of the medical sponge material are improved, and the medical sponge material has good application prospects. The application of the polylipoic acid-based porous material in the fields of hemostatic materials and wound dressings is realized.

An absorbent core for absorbent articles such as diapers comprising a core wrap comprising a top side and a bottom side, an absorbent material between the top side and the bottom side of the core wrap, a first and second longitudinally-extending channel-forming areas disposed on opposite sides of the longitudinal axis and substantially free of absorbent material preferably through which the top side of the core wrap is preferably attached to the bottom side of the core wrap. The core has a central absorbent zone between the first and the second channel-forming areas and a first and second lateral absorbent zones disposed laterally outwardly. The basis weight of the absorbent material in the central absorbent zone is higher than the basis weight of the absorbent material in each of the lateral absorbent zones for at least a first transversal section (S1). This relation is inverted along a second transversal section (S2) of the core. The first and second sections have each a length in the longitudinal direction of at least 10 mm.

An acellular product may be derived from human placenta and may be used in various scenarios for wound healing. Because the product may be acellular, the product may be processed for storage and transportation with minimal degradation. The product may include various scaffolding such as biomaterials or human tissue, and the scaffolding may be infused with various plasmas and agents. The cell-free treatment may maintain the biological activity of many therapeutic agents found within cells and may possess multiple structural components to support cellular attachment. The structural components or scaffolds may function as a reservoir of highly diffusible chemotactic and cellular-programming factors that may be useful to treat injury and disease.

The invention discloses application of plant-derived extracellular vesicles in preparation of a product for preventing and treating photoaging and a topical application composition. Pseudo-ginseng is used as a raw material for extraction and purification of plant-derived extracellular vesicles, and results show that the pseudo-ginseng-derived extracellular vesicles can significantly treat or improve photoaging. The invention explores the practical application of the fresh pseudo-ginseng extracellular vesicles based on the traditional theory of traditional Chinese medicine, and clarifies the molecular mechanism of the pseudo-ginseng extracellular vesicles. In a word, the extracellular vesicles derived from pseudo-ginseng have a wide application prospect in treatment of skin aging.

The present invention relates to a bio-based and biodegradable superabsorbent polymer (SAP) comprising sodium alginate, modified cellulose, at least one activation agent, and at least one crosslinking agent. The SAP exhibits a high bio-based content of up to 93% and fulfills industrial composting standards such as EN 13432. The crosslinking reactions are performed under mild conditions, including ambient temperatures and neutral to alkaline pH, eliminating the need for high thermal energy. The resulting SAP granules demonstrate excellent liquid absorption performance, rapid swelling, high retention, and no observed toxicity or skin sensitization. The invention provides a sustainable alternative to petroleum-based SAPs for use in hygiene products, agriculture, and other disposable applications.

An absorbent article including a non-woven substrate of one or more layers of meltblown fibers and a first layer of spunbond fibers and a second layer of spunbond fibers. The absorbent article further includes an absorbent core comprising at least one of fibers or a superabsorbent polymer. At least one of the non-woven substrate or the absorbent may be treated with an alcohol repellency (“AR”) treatment.

The invention belongs to the field of biological medicine and material science, and particularly relates to an intelligent response type piezoelectric nanofiber dressing and a preparation method and application thereof. According to the preparation method, polyvinylidene fluoride-trifluoroethylene, a high polymer material and inorganic nanoparticles are blended and spun through an electrostatic spinning technology, and then a photo-thermal component coating is subjected to surface in-situ oxidation and self-polymerization, so that the composite fiber membrane is prepared. Under the stimulation of ultrasound (US) and near-infrared laser (Laser), the fiber membrane can cooperatively activate the piezoelectric effect and the photothermal effect, generate a dynamic electric field and local high temperature, realize multi-mode cooperative killing of bacteria (the antibacterial rate exceeds 99%), and simulate an endogenous electric field to promote cell migration and wound healing. The dressing has good mechanical properties (the Young modulus is 15-20 MPa), hydrophilicity (the contact angle is about 30 degrees), biocompatibility and stability, is suitable for treatment of chronic infected wounds such as diabetes mellitus and the like, and has the advantages of on-demand activation and intelligent response.

The invention discloses a super absorbent material and side leakage prevention paper diapers, and belongs to the field of hygienic product materials. Comprising the following steps: cooling acrylic acid in an ice-water bath, and partially neutralizing the acrylic acid by using a sodium hydroxide solution; mixing potato starch with deionized water, and gelatinizing at high temperature to obtain gelatinized starch; mixing gelatinized starch, neutralized acrylic acid, potassium persulfate and deionized water; uniformly stirring under the protection of nitrogen, heating and carrying out graft copolymerization reaction to obtain a copolymer; adding modified silicon dioxide into the copolymer, and uniformly dispersing; then adding an oxetane compound, and carrying out a cross-linking reaction at a high temperature to obtain a super absorbent material; wherein the modified silicon dioxide has a porous structure, and nano-silver particles are loaded in pore walls. The super absorbent material disclosed by the invention effectively breaks through the gel blocking effect of the traditional high-molecular water-absorbent resin, has ultrahigh liquid absorption capacity and water locking capacity, and realizes slow-release long-acting bacteriostasis at the same time.

The invention provides a nano transdermal sustained-release biological scaffold as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. The nano transdermal sustained-release biological scaffold provided by the invention comprises the following components: a load and a nano carrier, the load comprises mussel mucin, trehalose and Ectoine; the mass ratio of the mussel mucin to the trehalose to the Ectoine is (4 to 6) to (0.5 to 1.5) to (0.5 to 2.0). Through the innovative design of a quaternary composite system of mussel mucin, trehalose, Ectoine and a nano-carrier, the three technical problems of short slow release period, insufficient targeting property and difficulty in large-scale production in a wound repair material in the prior art are successfully solved.

Provided are: polyurethane elastic fibers that achieve heat resistance, adhesiveness, and reelability and that are suitable for a gather member; a winding body therefor; a gather member; and a sanitary material. The present invention relates to: polyurethane elastic fibers that are multifilaments and that contain urethane bonds and urea bonds, the polyurethane elastic fibers being characterized in that the ratio of the urea bonds with respect to the urethane bonds is 0.05 to 5%; a winding body of said polyurethane elastic fibers, wherein the elongation rate of the polyurethane elastic fibers on the winding body is 0.05 to 10%; a gather member; and a sanitary material.

The invention relates to the technical field of medical materials, and discloses a chitosan spunlace degradable medical dressing base material and a preparation method thereof. Comprising the following operation steps that chitosan fibers, modified cellulose and viscose fibers are subjected to opening treatment and then mixed to be uniform, carding is conducted through a carding machine to form a net, cross laying is conducted, and a fiber net is obtained; performing spunlace reinforcement on the fiber net by adopting a flat net spunlace machine to obtain the chitosan spunlace non-woven fabric; carrying out vacuum defoaming on the spinning solution and then putting the spinning solution into a propulsion pump; the chitosan spunlace non-woven fabric is fixed to a collector for electrostatic spinning and drying, then the chitosan spunlace non-woven fabric is soaked in a zinc acetate ethanol solution for ultrasonic treatment for 5-10 min, ethanol cleaning, drying, cutting and packaging are conducted, and the chitosan spunlace degradable medical dressing base material is obtained.

The invention discloses antistatic medical gauze and a preparation method thereof, and relates to the technical field of medical gauze. The antistatic medical gauze comprises the following raw materials in parts by mass: 60-80 parts of cotton fibers, 1-5 parts of an antistatic agent, 5-15 parts of a water-soluble polymer and 0.5-1 part of an antibacterial agent. Compared with the traditional technology that the antistatic effect is transient and is easily influenced by environmental factors, the invention realizes long-acting and stable charge neutralization capability by introducing a specific micromolecule antistatic agent (such as a compound shown in the formula 1) and combining a moisture absorption conductive mechanism, an ionization effect and surface energy regulation. The trend shows that the static dissipation is faster and the effect is lasting, the problems of potential safety hazards and dust adsorption caused by charge accumulation are effectively avoided, and the defect that the effect of an antistatic agent in the prior art is not lasting is overcome.