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354 results about "Gel forming" patented technology

Cyclic structure betaine and double-tailed hydrophobic association polymer fracturing thickening agent and preparation method thereof

The invention relates to a ring structure betaine and double-tailed hydrophobic association polymer fracturing thickening agent and a preparation method thereof. The thickening agent is formed by copolymerization of four monomers, namely acrylamide, 2-allyl methylamino sodium ethanesulfonate, methyl diallyl sulfoethyl betaine and hydrophobic monomer double-tailed long-chain alkyl methyl allyl ammonium chloride. The preparation method comprises the following steps: firstly adding distilled water, then sequentially adding acrylamide, 2-allyl methylamino sodium ethanesulfonate, methyl diallyl sulfoethyl betaine and a hydrophobic monomer double-tailed long-chain alkyl methyl allyl ammonium chloride, adjusting the total concentration, introducing N2 to remove oxygen, adding an initiator, and reacting to prepare an AM / AMES / MDASBA / DCnMAAC quadripolymer, namely the polymer fracturing thickening agent. The thickening agent provided by the invention has good water solubility, and shows good salt resistance in mixed brine with the mineralization degree of greater than or equal to 30000 mg / L. The prepared linear solution and gel formed after crosslinking have high viscosity retention capacity at the temperature of 150 DEG C and the shearing rate of 170 s <-1 >, and the actual construction requirement for fracturing yield increase with the on-site mineralization degree larger than or equal to 30000 mg / L is met.
Owner:HEBEI PETROLEUM VOCATIONAL & TECH UNIV

Acid-reducing soil conditioner for southern red soil dry land and preparation method of acid-reducing soil conditioner

The invention provides a southern red soil dry land deacidification soil conditioner and a preparation method thereof, and belongs to the technical field of soil conditioners. The preparation method comprises the following steps: embedding bacillus subtilis, bacillus licheniformis and bacillus amyloliquefaciens to prepare bacterial microspheres, adding the bacterial microspheres into gel formed by carboxymethyl chitosan and silk fibroin peptide to prepare sustained-release bacterial microsphere gel, uniformly mixing the sustained-release bacterial microsphere gel with porous silicon dioxide loaded with basalt and charcoal, and drying to prepare the acid-reducing soil conditioner for the southern red soil dry land. The acid-reducing soil conditioner for the southern red soil dry land not only improves the pH value of the soil, but also can loosen the soil and improve the air permeability of the soil to a certain extent, and promotes the absorption of crops to moisture and nutrient elements by improving the physical and chemical properties of the soil, so that the normal growth of the crops is ensured, and the acid-reducing soil conditioner has a wide application prospect.
Owner:HUNAN SOIL & FERTILIZER INST +2

Tissue adhesive based on mussel mucin as well as preparation method and application of tissue adhesive

The invention discloses a tissue adhesive based on mussel mucin as well as a preparation method and application thereof. The tissue adhesive is prepared from mussel mucin and an anionic compound containing a hydrophobic group, the mussel worm electrostatic self-assembly bionic composite material is developed on the basis of triple bionic principles of dopa adhesion of mussel byssus, electrostatic self-assembly polymerization of sandburg worms and hydrophobic acting force of barnacles. The preparation method of the tissue adhesive is simple, the tissue adhesive can be obtained only by mixing and oscillating the two stock solutions, the gel forming condition is simple and easy to implement, the pH range and the stock solution concentration range required by gel forming are large, the gel forming range is wide, the raw materials required in the preparation process are few, and the cost is low. Only two key raw materials including the mussel mucin and the anionic compound containing the hydrophobic group are needed, and the prepared tissue adhesive is high in adhesion speed and high in adhesion strength, has good cell compatibility and biological safety and can promote wound healing.
Owner:NANJING TECH UNIV

Preparation method of polyurethane pultrusion resin composite material

ActiveCN120697342AGlass fiberPolymer science
The invention relates to the technical field of polyurethane pultrusion, in particular to a preparation method of a polyurethane pultrusion resin composite material, which comprises the following steps: drawing glass fiber into a glue dipping tank filled with polyurethane resin for dipping; heating the impregnated glass fiber in a pre-forming mold to obtain a pre-cured gel forming body; when it is judged that preparation of the pre-cured gel forming body does not meet the preset standard according to the scattering intensity standard deviation of the pre-cured gel forming body, preparation parameters are adjusted; the pre-cured gel forming body meeting the preset standard is put into a pultrusion mold for pultrusion, and a cured forming body is obtained; when it is judged that the preparation of the cured molded body does not meet a preset standard according to the average ripple amplitude, determining an adjustment strategy for the preparation of the cured molded body to do not meet the standard according to the curvature variance of the surface lines; and pulling and naturally cooling the cured molded body meeting the preset standard to obtain the polyurethane resin composite material. The preparation efficiency of the resin composite material is improved.
Owner:TIANJIN JUSHI NEW MATERIAL TECH CO LTD

Octane alkoxy modified imine gelator, bi-component gel as well as preparation method and application of bi-component gel

The invention relates to the technical field of organic supramolecular chemical materials, in particular to an octyloxy-modified imine gelator, bi-component gel of the octyloxy-modified imine gelator and a preparation method and application of the octyloxy-modified imine gelator. The gelator is a symmetric o-octyloxy modified p-phenylenedialdehyde-maleonitrile imine gelator, and has an obvious aggregation-induced emission property; the gelator and the cholesteryl half-ester gel can form double-component organic gel without fluorescence emission in an organic solvent; the fluorescence-emission-free double-component gel formed in tert-butyl alcohol is red fluorescence-emission gel when meeting water, and is converted into blue fluorescence-emission gel when meeting NaClO, so that water and NaClO can be rapidly and intuitively detected; the gelator has fluorescence enhancement and blue shift after encountering NaClO in a solution state, has fluorescence'off-on 'detection on NaClO, has fluorescence emission intensity reduced after Hg < 2 + > is added in the solution state, and has fluorescence'on-off' detection performance on Hg < 2 + >.
Owner:DEZHOU UNIV

Method for comprehensively recovering silicon and magnesium based on rotary kiln-electric furnace type ferronickel slag

The invention discloses a method for comprehensively recovering silicon and magnesium based on rotary kiln-electric furnace type ferronickel slag. The method comprises the following steps: carrying out ball milling, leaching and solid-liquid separation on the rotary kiln-electric furnace type ferronickel slag, standing supersaturated silicon in a leaching solution at normal temperature to generate a gel phenomenon, stirring and crushing to obtain a mixed phase of a magnesium sulfate solution and a silica gel block, and separating the gel solution to obtain a magnesium sulfate crude solution and wet crude silica gel; preparing high-purity hydrated magnesium sulfate with the purity of 99.9% from the magnesium sulfate crude liquid through processes of purification, crystallization and the like; the wet coarse silica gel is subjected to further alkali dissolution, gel forming and other processes to produce silica gel with the purity of 99%; the method has the advantages of low energy consumption, high product added value and element recovery rate and convenience in industrialization, and has excellent popularization and application prospects.
Owner:GUANGXI UNIV

Ceramic three-dimensional (3D) printing device based on gel molding process and control method

The present disclosure provides a ceramic three-dimensional (3D) printing device based on a gel molding process and a control method. The ceramic 3D printing device based on a gel molding process includes a feeding assembly, a receiving assembly, a scraping assembly, and a spray assembly. The feeding assembly includes a feeding pump and a storage hopper. The receiving assembly includes a feeding rod. The feeding pump can convey slurry in the storage hopper to the feeding rod. The control method includes introducing the atomized liquid into the storage hopper and the bearing groove through the first spray pipe and the second spray pipe respectively. According to the present disclosure, a water content of the slurry can be controlled to achieve a better curing effect.
Owner:SHENZHEN ADVENTURE TECH CO LTD

Efficient grinding diamond abrasive and preparation process thereof

The invention relates to the field of abrasive materials, in particular to an efficient grinding diamond abrasive material and a preparation process thereof.The efficient grinding diamond abrasive material is prepared by coating diamond micro-powder for multiple times to prepare composite diamond micro-powder, then blending the composite diamond micro-powder with electrolytic copper powder, filler, a wetting agent and modified polyvinyl alcohol to obtain slurry, and conducting freezing-unfreezing gel forming to obtain the efficient grinding diamond abrasive material. The prepared diamond grinding material is good in water resistance and efficient in grinding; the preparation method comprises the following steps: depositing a tungsten coating on the surface of diamond micro-powder, then carrying out vacuum high-temperature treatment to obtain pretreated diamond micro-powder with a tungsten carbide layer growing in situ on the surface, generating a silicon oxide layer on the pretreated diamond micro-powder by using tetraethoxysilane, and then generating praseodymium-doped cerium oxide nanoparticles on the surface of the modified diamond micro-powder by using a homogeneous precipitation method; the preparation method comprises the following steps: carrying out chain extension treatment on a prepolymer generated by polytetrahydrofuran ether glycol and 4, 4 '-dicyclohexylmethane diisocyanate by using a silicon-containing chain extender to obtain a polyurethane prepolymer, and then modifying polyvinyl alcohol by using the polyurethane prepolymer and phenolic resin.
Owner:NANJING JINRUI LIFENG HARD MATERIAL TECH CO LTD

Pseudo-boehmite, preparation method thereof and gamma-alumina carrier with high diffusion mass transfer performance

The invention provides pseudo-boehmite, a preparation method thereof and a gamma-alumina carrier with high diffusion mass transfer performance. The preparation method comprises the following steps: respectively preheating an aluminum-containing acidic solution, a sodium metaaluminate solution and reaction bottom water to gel forming reaction temperature; under stirring, dropwise adding the first part of the aluminum-containing acidic solution and the first part of the sodium metaaluminate solution into the reaction bottom water, controlling the pH value of the gelling reaction to be 5.0-8.5, and uniformly mixing to obtain material slurry; dropwise adding all the residual aluminum-containing acidic solution and the residual sodium metaaluminate solution into the material slurry, and carrying out gel forming reaction to obtain reaction slurry; and carrying out step-by-step variable-temperature aging on the reaction slurry, and carrying out suction filtration, washing and drying to obtain the pseudo-boehmite. According to the method, the problem of poor pore regulation flexibility in a traditional double-aluminum method is solved, the limitation of the pore size can be overcome, and the pore permeability of the gamma-alumina carrier is improved, so that the diffusion mass transfer performance of the gamma-alumina carrier is greatly enhanced.
Owner:CHINA UNIV OF PETROLEUM (BEIJING)

Raw material composition of bionic esters, D-phase gel, application and cosmetics

PendingCN120168356ACosmetic preparationsToilet preparationsPolyolIsostearyl alcohol
The invention discloses a raw material composition of bionic esters, D-phase gel, application and cosmetics. The biomimetic ester is prepared from the following raw material compositions: phytosterol isostearyl alcohol dimer linoleate, phytosterol / isostearyl alcohol / cetyl alcohol / stearyl alcohol / behenyl alcohol dimer linoleate, hydrogenated lecithin and polyhydric alcohol. The bionic ester raw material composition disclosed by the invention can be directly added into various cleaning products containing a surfactant, and the problems that the surfactant added into a washing-off cleaning product is easy to cause excessive skin degreasing, the washed skin is dry, and the skin feels tight can be solved by using a small addition amount; meanwhile, the cleaning power, the foam amount and the mildness of the cleaning product are not influenced. The D-phase gel formed by the raw material composition of the biomimetic esters prepared by the invention is arranged in a layered liquid crystal structure.
Owner:SHANGHAI HUIWEN BIO TECH

Fabricated wall cementing material prepared from multi-element solid waste and preparation method of fabricated wall cementing material

The invention relates to the technical field of building materials, in particular to a cementing material for a fabricated wall prepared from multi-element solid waste and a preparation method of the cementing material. The preparation method comprises the following steps: 25-55 parts of fly ash, 25-65 parts of blast furnace slag, 8-10 parts of lime, 1-5 parts of desulfurized gypsum, 3-6 parts of a first mixture, 2-5 parts of a second mixture and 5-8 parts of an alkali activator; the mass ratio of the metakaolin to the bentonite to the superfine calcium carbonate in the first mixture is 3: 2: 1; the mass ratio of the vermiculite to the expanded perlite to the glass beads in the second mixture is 2: 2: 1. Through the synergistic excitation effect of Ca < 2 + > and Na < + > and the addition of the first mixture and the second mixture, the cementing material forms a more stable microstructure. A hydration product SEM figure shows that C-S-H and C (N)-A-S-H gel are symbiotic to form a three-dimensional network, pores are filled with needle-like ettringite crystals, and in combination with the brucite phase anchoring effect, the mechanical properties, such as strength and durability, of the material are remarkably improved.
Owner:INNER MONGOLIA HUIFANG NEW BUILDING MATERIALS CO LTD +1

Preparation method of ultrasonic-guided injectable degradable hemostatic hydrogel

The invention discloses a preparation method of injectable hemostatic glue, which comprises the following steps: step 1, synthesizing oxidized hyaluronic acid: dissolving hyaluronic acid in distilled water, adding NaIO4, stirring, dialyzing a reaction product after the reaction is finished, and then freeze-drying to obtain the oxidized hyaluronic acid; the epsilon-polylysine and the oxidized hyaluronic acid obtained in the step 1 are dissolved in a PBS buffer solution, an oxidized hyaluronic acid solution and an epsilon-polylysine solution are mixed, the epsilon-polylysine / oxidized hyaluronic acid hydrogel can be obtained, and the pH value of the mixed solution is preferably 5.0-13.0. According to the method, the hemostatic gel solution can be injected to visceral hemorrhage and external hemorrhage, is gelled in situ at a wound, can be automatically degraded in vivo, and can be taken out without an operation. Taking a liver hemorrhagic point as an example, the hydrogel effectively solves the problem of closed bleeding of the liver. The preparation method provided by the invention is mild in condition and convenient to operate, and gel forming is easy to control.
Owner:INST OF MEDICAL ROBOTICS & INTELLIGENT SYST TIANJIN UNIV

Aerogel heat insulation pipe shell and preparation method and application thereof

The invention relates to the related field of heat insulation composite material processing, in particular to an aerogel heat insulation pipe shell and a preparation method and application thereof, and the aerogel heat insulation pipe shell is composed of a fiber needled felt without a binder and silicon dioxide aerogel. The manufacturing method comprises the steps of fibrofelt cutting and pre-rolling, sol preparation, rotary dynamic gel forming, supercritical drying, two-end trimming and opening treatment, and the tubular prefabricated part which is accurate in size, convenient and fast to install and capable of replacing aerogel felt is mainly applied to various pipelines and cylindrical equipment needing heat insulation and insulation. Loss of on-site construction materials and consumption of auxiliary materials can be effectively reduced, the construction period is shortened, and the heat insulation engineering quality is improved.
Owner:JIANGSU HANXIN TIANCHENG NEW MATERIAL CO LTD +1

Gel composition for improving compatibility and gelling speed of tooth whitening product and preparation method

The invention discloses a gel composition for improving compatibility and gelling speed of a tooth whitening product. The gel composition comprises whitening gel and a catalyst, respectively filling the whitening glue and the catalyst into a double-barrel injector; when the tooth whitening gel is used, the push rod is pushed, the whitening gel and the catalyst in the double-tube barrel are squeezed out at the same time and mixed at the mixing head to form the tooth whitening gel capable of being smeared on the tooth surface of a patient, and the pH value of the tooth whitening gel is 7.5-10.0. The catalyst comprises potassium salt or strontium salt, sodium fluoride, glycerol, cross-linked polyacrylamide gels, strong alkaline substances, essence and water; the whitening gel comprises a hydrogen peroxide solution, a cross-linked polyacrylamide gel, glycerin, essence and water. The cross-linked polyacrylamide gel is adopted, the gel is resistant to strong-alkalinity and high-pH environment and various inorganic salt ions such as fluoride, sylvite or strontium salt, the prepared gel is stable in form and good in compatibility, the gel preparation process is simple, the gel is rapidly swelled when encountering water and does not huddle, and long-time standing is not needed.
Owner:HAOBAI (ZHEJIANG) MEDICAL EQUIP CO LTD

High-adhesion enzymatic hydrogel capable of promoting endometrial repair and preparation method of high-adhesion enzymatic hydrogel

The invention discloses a high-adhesion enzymatic hydrogel for promoting vascular intima repair and a preparation method of the high-adhesion enzymatic hydrogel, and belongs to the technical field of hydrogel preparation. The preparation method comprises the following steps: S1, carrying out double-bond modification on hyaluronic acid by utilizing methacrylic anhydride, and then cross-linking with dopamine to prepare dopamine modified double-bond hyaluronic acid; s2, deoxidizing the hyaluronic acid solution, adding a cross-linking agent and tyramine hydrochloride, and reacting in an acidic environment to prepare tyramine modified hyaluronic acid; s3, mixing the dopamine modified double-bond hyaluronic acid, the tyramine modified hyaluronic acid and deionized water to prepare a hydrogel precursor liquid; and S4, carrying out enzymatic reaction to obtain the hydrogel. The method designed by the invention is simple in process, no extra photocuring equipment needs to be added, and the constructed hydrogel is similar to an extracellular matrix. And the coating can be coated into different shapes to adapt to different environments. The gel is formed through enzymatic reaction, and the gel is rapid in gel forming, good in tissue adhesion, good in biocompatibility and suitable for being applied to vascular repair.
Owner:SOUTHWEST JIAOTONG UNIV

Composite hydrogel adsorbent as well as preparation method and application thereof

The invention discloses a composite hydrogel adsorbent and a preparation method and application thereof, and belongs to the technical field of wastewater treatment.The preparation method comprises the specific steps that S1, neutralized acrylic acid, acrylamide and a cross-linking agent are added into deionized water and stirred to be uniform, and a precursor solution is obtained; s2, adding alkali-activated fly ash into the precursor solution, uniformly mixing, sequentially adding alkali liquor and an initiator, and fully stirring for reaction to obtain a mixed solution; and S3, curing the obtained mixed solution in a mold, washing with water, and drying to obtain the composite hydrogel adsorbent. According to the invention, the reaction system is optimized, so that the super-fast polymerization curing of the hydrogel is realized; the prepared composite hydrogel has excellent mechanical property and metal ion adsorption property; the whole preparation process is simple to operate, high in gel forming speed, free of light / heat initiation, mild in condition and low in cost, and can be applied to adsorption of heavy metal ions in wastewater.
Owner:SHANXI COAL TRANSPORTATION & MARKETING GRP JINNENG COAL MINE ENG CO LTD

Polyethylene glycol derivative-collagen injectable cartilage repair gel as well as preparation method and application thereof

The invention provides a polyethylene glycol derivative-collagen cartilage repair gel which is characterized by being prepared from the following components in parts by weight: 8 to 12 parts of collagen (namely COL) solution, 0.5 to 2 parts of polydeoxyribonucleotide (namely PDRN), 4 to 8 parts of polyethylene glycol disuccinimide succinate (namely SS-PEG-SS) solution and 0.1 to 0.4 part of tannic acid (namely TA), and particularly discloses a preparation method and application of the polyethylene glycol derivative-collagen cartilage repair gel. In a word, the composite gel and the collagen are subjected to efficient amidation reaction through SS-PEG-SS to form a stable three-dimensional network, so that the structural support of the type I collagen, the tissue repair of PDRN and the anti-inflammatory and anti-oxidation characteristics of tannic acid are successfully integrated; therefore, the composite material has the comprehensive performance of good structural stability, high mechanical strength, good biocompatibility, controllable degradation period, excellent needle passing performance and the like, and shows the wide application prospects of clear repair effect, remarkable component synergistic effect, mature production process, outstanding cost effectiveness and the like.
Owner:BEIJING UNIV OF CHEM TECH

Method of implantation of a medical device into neural tissue

A method of providing a channel in nervous tissue filled with an aqueous gel for implantation of a microelectrode or other medical device lacking sufficient physical stability for direct implantation by insertion, comprises providing an apparatus comprising an oblong rigid pin covered by a dry gel forming agent; locating a target in the tissue; defining a straight insertion path a desired tissue insertion point and the target; aligning the pin with its end foremost with the insertion path; inserting the pin into the tissue to a position near or at the target; allowing sufficient time to pass for a gel to be formed around the pin, withdrawing the pin. Also disclosed is a corresponding channel; a method of implantation of a microelectrode or microprobe into nervous tissue via the channel; a corresponding method of implantation of living cells; a corresponding apparatus for forming the channel.
Owner:NEURONANO AB

Progesterone vaginal sustained-release gel and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, in particular to progesterone vaginal sustained-release gel and a preparation method thereof, and the preparation method comprises the following steps: S100, raw material pretreatment; s200, preparing a hydrogel; s300, preparing an oil phase system; and S400, gel forming is carried out. Through accurate preparation steps and strict quality control, it is ensured that a uniform porous network structure is presented in the gel and progesterone nanocrystals are uniformly distributed in the gel, so that slow and continuous release of the medicine is achieved, in addition, the adhesion performance of the gel is optimized, the gel can be retained in the vagina for a long time, and the effect that the progesterone nanocrystals are uniformly distributed in the gel is achieved. The local action effect of the medicine is further enhanced, the curative effect of the medicine is improved, the administration frequency is reduced, and greater convenience and comfort are brought to patients.
Owner:JIANGSU VANGUARD PHARM CO LTD

Sodium hyaluronate gel regeneration filler for injection as well as preparation method and application of sodium hyaluronate gel regeneration filler

The invention belongs to the technical field of medical biological materials, and particularly relates to a sodium hyaluronate gel regeneration filler for injection and a preparation method and application thereof.The sodium hyaluronate gel serves as a carrier to disperse acellular matrix particles, the sodium hyaluronate gel forms a micron-sized porous structure in the cross-linking process through a microbubbling technology, and the sodium hyaluronate gel is prepared into the sodium hyaluronate gel regeneration filler for injection and the preparation method and application of the sodium hyaluronate gel regeneration filler. A local cross-linked network is strengthened by combining a secondary cross-linking process, high elastic modulus is realized while the content of sodium hyaluronate is reduced, so that the porous structure has excellent instant filling and shaping capability and controllable degradation behavior, the porous structure can promote permeation of hyaluronidase, the degradation period of the hyaluronidase is matched with the tissue regeneration process, and the tissue regeneration effect is improved. And the acellular matrix particles can continuously induce adhesion, migration, proliferation and differentiation of endogenous cells of tissues, synergistically promote in-situ tissue regeneration, effectively reduce repeated injection requirements and reduce long-term complication risks, and have a good application prospect in soft tissue filling and repairing.
Owner:SHANGHAI BAIYIYUAN BIOENGINEERING CO LTD

Rapid and long-acting gynecological antibacterial gel and preparation method thereof

The invention discloses a quick and long-acting gynecological antibacterial gel and a preparation method thereof. According to the formula of the gynecological antibacterial gel, a plurality of key components are selected and combined, and the gynecological antibacterial gel specifically comprises the following components in parts by weight: 5-15 parts of poloxamer, 0.5-1 part of carbomer, 0.5-1 part of N, N-dicarboxymethyl alanine trisodium salt, 0.2-0.1 part of carboxymethyl cellulose and 50-250ppm stable chlorine dioxide powder. The preparation method of the gynecological antibacterial gel comprises the five steps of chlorine dioxide chelating solution preparation, gel matrix preparation, gel forming, pH value adjustment and finished product packaging, all the steps are accurately controlled, and the product quality is ensured. The invention provides a gynecological gel product which is high in initial flowability, can be quickly gelated in vivo and has a quick long-acting antibacterial function, solves the problems of non-ideal antibacterial effect, inconvenience in use, insufficient safety and the like of an existing gynecological nursing product, ensures the safety and stability of the product, overcomes many defects of a traditional product, and has a good application prospect. And a better choice is provided for female reproductive health care.
Owner:HUNAN QIAOFEI BIOTECHNOLOGY CO LTD

Microbial immobilized particle reinforced by zero-valent iron shell as well as preparation and application of microbial immobilized particle

The invention discloses zero-valent iron shell reinforced microbial immobilized particles as well as preparation and application thereof, and belongs to the technical field of wastewater treatment. According to the preparation method, anaerobic digestion bacteria and a zero-valent iron reinforced material are embedded in porous organic gel formed by cross-linking polymerization of polyvinyl alcohol or sodium alginate in a layered manner, so that stress of an external poor water quality environment and the zero-valent iron material on microorganisms is reduced; in the prepared zero-valent iron shell reinforced microbial immobilized particle, the shell containing the zero-valent iron can protect microorganisms from being disturbed by external adverse environmental conditions, the environmental adaptability of the microorganisms is improved, and meanwhile the biological activity of the microorganisms in the porous inner core is reinforced; on the other hand, the biological toxicity of the zero-valent iron material to microorganisms is reduced, and the broad-spectrum applicability of the zero-valent iron is improved.
Owner:NANJING UNIV

Temperature-sensitive contact lens eye moistening gel and preparation method thereof

The invention belongs to the technical field of contact lens care, and provides temperature-sensitive contact lens eye-moistening gel and a preparation method thereof. The temperature-sensitive contact lens eye-moistening gel is prepared from the following raw materials in parts by mass: a gel matrix, a surfactant, an osmotic pressure regulator, an active component, a chelating agent, a buffering agent and the balance of injection water, the composition of the gel matrix is defined. Chitosan, sodium hyaluronate and polyvinyl alcohol are compounded to serve as a gel matrix, a polyelectrolyte compound is formed, gelation time is shortened, gel strength and swelling resistance are improved, biocompatibility is improved, and drug-loaded delivery of active ingredients is achieved; the gel matrix and the surfactant are reasonably selected, the viscosity of the solution is increased, the gelation time is shortened, the excellent effect of relieving eye fatigue and dryness is achieved, the wearing comfort of the contact lens is remarkably improved, and the oxygen permeation effect of the contact lens is not obviously reduced after gel forming.
Owner:GANSU TIANHOU OPTICAL TECHNOLOGY CO LTD

Hydrogel based on self-adaptive biological catalytic system, preparation method and application of hydrogel as dressing for wound surface of diabetes mellitus

The invention discloses hydrogel based on a self-adaptive biological catalysis system, a preparation method and application of the hydrogel as a diabetes wound dressing, and the preparation method of the hydrogel comprises the following steps: weighing oxidized sodium alginate, adding the oxidized sodium alginate into ultrapure water for dissolving, adding gelatin, glucose oxidase and catalase, uniformly stirring to obtain a gel solution, and carrying out freeze drying on the gel solution to obtain the hydrogel. And heating, preserving heat and standing until the gel is formed. Oxidized sodium alginate (OSA) and gelatin (GEL) are coupled to generate pH-sensitive Schiff base bond crosslinking, glucose oxidase (GOx) and catalase (CAT) are loaded in the pH-sensitive Schiff base bond crosslinking, and dynamic gel capable of interacting with the environment is prepared; the hydrogel can interact with the micro-environment (pH, glucose and the like) of the chronic wound surface of the diabetes mellitus, and can be used as a micro-environment adaptive and adjustable dressing for treating the wound surface of the diabetes mellitus.
Owner:EAST CHINA NORMAL UNIV +1

Homogeneous gel composition for dermis filling, and preparation method therefor and use thereof

Disclosed in the present invention are a homogeneous gel composition for dermis filling, and a preparation method therefor and the use thereof. The homogeneous gel composition comprises: (Y1) second biocompatible solid particles; and (Y2) a gel material. The gel material comprises the following components: (Z1) first biocompatible solid particles; (Z2) hyaluronic acid; and (Z3) a cellulose-based polysaccharide polymer, wherein the gel material is in a solid powder or gel form. The homogeneous gel composition prepared in the present invention comprises high- and low-association-degree biocompatible solid particles, such that the biocompatible solid particles are gradually released in a matrix, and the biocompatible solid particles can stably exist in a composite system for a long time.
Owner:OSDERMA MEDICAL INC

Modified polypeptide as well as preparation method and application thereof

The invention discloses a modified polypeptide as well as a preparation method and application thereof, the preparation method comprises the following steps: on the basis of solid-phase synthesis of RADA16, 1-hydroxybenzotriazole and benzotriazole-N, N, N ', N'-tetramethylurea hexafluorophosphate are adopted as condensing agents, N, N-diisopropylethylamine-containing N, N-diisopropylethylamine is added into the condensing agents, and a reaction is carried out for 2-4 hours to obtain the modified polypeptide. And adding amino-terminated or carboxyl-terminated polyethylene glycol or amino-containing chitosan oligosaccharide into N, N-dimethylformamide for condensation, cutting polypeptide from the resin after the reaction is completed, precipitating, washing, re-dissolving and freeze-drying to obtain the polypeptide. The polypeptide provided by the invention has the characteristic of forming hydrogel through self-assembly in a specific medium, and the gel forming time of the polypeptide is within 21-60 seconds and is obviously faster than that of RADA peptide (gel forming in 150 seconds) under the same condition; the polypeptide modified by the polyethylene glycol or the chitosan oligosaccharide can spontaneously form gel after being injected into the blood vessel so as to embolize the blood vessel, and the embolism is long in stabilization time and stable, and meets the actual clinical requirements.
Owner:LISHUI CENT HOSPITAL

Preparation method of cell-loaded silk fibroin hydrogel fiber and fiber

The invention relates to a preparation method of cell-loaded silk fibroin hydrogel fibers and fibers, the preparation method of the cell-loaded silk fibroin hydrogel fibers comprises the following steps: mixing a silk fibroin solution with a riboflavin solution to obtain a mixed solution, adding a hydrogen peroxide solution into the mixed solution to obtain a precursor solution, and carrying out ultrasonic treatment on the precursor solution to obtain the cell-loaded silk fibroin hydrogel fibers. Adding stem cells into the precursor solution, and then carrying out photocuring reaction under the irradiation of an ultraviolet lamp to prepare the hydrogel fiber. The fiber is obtained through the preparation method. According to the preparation method of the cell-loaded silk fibroin hydrogel fiber and the fiber, the gel forming time is greatly shortened, efficient and uniform loading of cells is achieved, the survival rate of the cells is increased, no organic reagent residues exist in the preparation process, operation is easy, the technological process is short, and the method is suitable for industrial production. The prepared fiber is free of biotoxicity, excellent in mechanical property, good in light transmission and good in biocompatibility, and has certain potential and application prospects in the biomedical field.
Owner:WUHAN TEXTILE UNIV

Novel rotating wheel with dual functions of deodorization and dehumidification and preparation method of novel rotating wheel

The invention discloses a novel rotating wheel with dual functions of deodorization and dehumidification. The novel rotating wheel comprises a honeycomb base body formed by overlapping and rolling glass fiber paper corrugated sheets and flat sheets, a silica gel main framework layer covering hole walls, and a deodorization function layer fixed on the surface of the silica gel main framework layer. The silica gel main framework is prepared from water glass through carbon dioxide pressurization gel forming, acid aging, graded drying and calcination, and is uniform in structure and high in strength. The deodorization function layer is composed of modified silicon dioxide particles and a rare earth or transition metal complexing stable center, and a stable chemical bonding interface is formed. The rotating wheel has efficient dehumidification and peculiar smell adsorption capacities, and is small in airflow resistance and good in circulation stability.
Owner:HANGZHOU PURUI DEHUMIDIFICATION EQUIP CO LTD

Anti-swelling hydrogel capable of quickly gelling and preparation method of anti-swelling hydrogel

PendingCN120248527APolymer scienceMeth-
The invention relates to the field of anti-swelling hydrogel materials, and discloses a preparation method of anti-swelling hydrogel capable of rapidly gelling. Polyallylamine hydrochloride and acrylate are used as raw materials, persulfate is used as an initiator, N, N '-methylenebisacrylamide is used as a cross-linking agent, preparation of a polymer is realized by adopting a free radical polymerization method, construction of an elastic network is realized by utilizing electrostatic interaction and chemical cross-linking, and the dosage of the raw materials is optimized. Finally, the anti-swelling hydrogel capable of rapidly gelling is prepared, the gel forming speed is high, and water molecules are difficult to permeate into a network due to the compactness of the cross-linked network, so that the volume change of the hydrogel after water absorption is reduced, and the gel has anti-swelling performance.
Owner:CHANGZHOU UNIV

Artificial nail tip and curing composition set and applying method thereof

A nail tip curing composition includes an Extend Gel, an edge-off flat brush, a nail filing device, a plurality of GEL-X tips, a pH Bonder, and a Non-Acidic Gel Primer. The pH Bonder forms a pH Bonder layer on a surface of a fingernail. The Non-Acidic Gel Primer forms a Non-Acidic Gel Prime layer overlapped on the pH Bonder layer. The Extend Gel forms an Extend Gel layer overlapped on the Non-Acidic Gel Prime layer. The GEL-X tip is filed by the nail filing device and the Extend Gel is applied on an underside contact surface of the Gel-X tip by the edge-off flat brush. The underside contact surface of the Gel-X tip is contacted with the Extend Gel layer on the fingernail in such a manner that the Gel-X tip is firmly affixed on the fingernail.
Owner:APPLIED LACQUER IND INC