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151 results about "Conjunctiva" patented technology

The conjunctiva is a tissue that lines the inside of the eyelids and covers the sclera (the white of the eye). It is composed of unkeratinized, stratified squamous epithelium with goblet cells, and stratified columnar epithelium. The conjunctiva is highly vascularised, with many microvessels easily accessible for imaging studies.

Azastine hydrochloride eye drops for treating allergic conjunctivitis and preparation method thereof

According to the nitrogen hydrochloride # imgabs0 # stine eye drops for treating allergic conjunctivitis and the preparation method of the nitrogen hydrochloride # imgabs0 # stine eye drops, the prepared eye drops can interact with the mucous layer on the surface of keratoconjunctiva by selecting specific solid lipid and a surfactant and controlling the dosage of the solid lipid and the surfactant; the retention capacity of the medicine in front of the cornea is prolonged, so that the medicine has good targeting property, the continuous release of the medicine is realized, the medication frequency can be reduced, the toxic and side effects of the medicine are reduced, the bioavailability is improved, the medication compliance of a patient is enhanced, and in the preparation and long-term storage processes, the medicine has better stability, and is suitable for popularization and application. Therefore, the problems of excessive drug due to multiple administration and poor stability of the active component nitrogen hydrochloride # imgabs1 # stine are solved.
Owner:NANJING HEALTHNICE MEDICAL TECH +3

Screening method of sicca syndrome markers based on conjunctival blotting

The invention discloses a screening method of sicca syndrome markers based on conjunctival blotting, and relates to the technical field of biomedicine, and the screening method comprises the following steps: S1, conjunctival noninvasive sampling; s2, RNA (Ribonucleic Acid) sequencing and pathway screening; s3, machine learning modeling is carried out; s4, clinical verification. According to the invention, biomarker screening is realized, and similar biomarker screening can also be realized through tear sample analysis or other ophthalmic samples; however, the alternative schemes have the defects of relatively strong invasiveness, complex operation and the like; sampling is carried out through the conjunctival imprinting technology, invasive operation such as biopsy and blood drawing is avoided, and pain and discomfort are reduced; differential expression genes can be accurately identified, and the sensitivity and the accuracy are relatively high; through immune cell infiltration analysis, the relationship between the immune cell subpopulation and the sicca syndrome related gene is disclosed, a new perspective is provided for a disease mechanism, and a theoretical basis is provided for a future immune regulation strategy.
Owner:THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY

Method and device for treating eye disease

Described herein are devices used to treat high intraocular pressure and glaucoma. An example device includes a plate comprising a first surface opposite a second surface. The first surface includes a series of fluid channels. The device also includes a first coating on the first surface and a second coating on the second surface. The device is configured to lower intraocular pressure by draining aqueous humor from an anterior chamber to subconjunctival space of a patient's eye.
Owner:AVISI TECH INC

Docking station for ophthalmic surgery

A docking device for intraocular surgery is provided having an upper edge portion having a second diameter, a lower edge portion having a first diameter and a bottom surface with at least one aperture, and a sidewall extending between the upper edge portion and the lower edge portion. An arm is also provided having a first portion coupled to the central portions of the upper and lower edge portions and a second portion configured for connection to a positioning arm. The lower edge portion also has a lower surface having a suitable profile configured to be secured to the sclera and / or conjunctiva of the surgical eye. Optionally, the lower surface of the upper edge portion is adapted and configured to releasably engage with the upper surface of the lower edge portion. Other variations include a split coupling that allows the suction surface to remain coupled to the surgical eye while removing other portions of the docking device.
Owner:HORIZON SURGICAL SYSTEMS INC +1

Novel eye drug delivery and release system

The utility model provides a novel eye drug delivery and release system which sequentially comprises a main body base layer and a waterproof isolation layer from outside to inside, the main body base layer and the waterproof isolation layer are fixedly attached together, and at least one drug storage and release layer is attached to the waterproof isolation layer. The medicine storage and release layer is used for storing ophthalmology medicine and releasing the ophthalmology medicine into eyes when the ophthalmology medicine is in contact with the eyes, the medicine storage and release layer comprises a base layer and an upper layer which are attached together, the base layer is a methyl cellulose layer, and the upper layer is a polycaprolactone layer. According to the utility model, medicine is administrated on the bitamporal sides of two eyes, and medicine quickly passes through the lower lacrimal punctum, so that medicine loss is reduced; a patient does not need to directly face the medicine bottle, fear of the patient is reduced, and the medicine bottle is prevented from touching eyes by mistake; the disposable liquid medicine bottle is disposable, high in comfort level, convenient to operate, capable of being used in cooperation with most of liquid medicine and high in applicability. The effective duration and concentration of eyelid margin medication can be increased, and the effectiveness is higher; the eye cleaning device has various functions and can also be used for cleaning eye conjunctival sacs and eyelid margins.
Owner:CHONGQING HUAXIA OPHTHALMIC HOSPITAL CO LTD

Superoxide dismutase and use thereof in prevention or treatment of dry eye

The present invention relates to superoxide dismutase and its use in the prevention or treatment of dry eye. More specifically, the present invention relates to a pharmaceutical composition or a treatment method for preventing or treating dry eye. According to the compositions and methods of the present invention, an increase in the secretion amount selected from tear fluid can be achieved; the tear film rupture time is prolonged; minimizing ocular surface damage; goblet cells in the conjunctiva are protected; the number of immune cells and inflammatory cell factors in cornea and conjunctiva is reduced; reduction of oxidative stress in cornea, conjunctiva and lacrimal gland; and a reduction in corneal epithelial cell apoptosis, thereby being effectively used in the prevention or treatment of dry eye.
Owner:GENOFOCUS CO LTD +1

Periocular postoperative nursing paste

The utility model relates to the technical field of clinical nursing appliances, and provides a periocular postoperative nursing patch aiming at the problem that a wound is pulled due to the fact that an existing eye nursing patch is easily adhered to conjunctiva or eyelashes by mistake, the periocular postoperative nursing patch comprises a periocular patch, and an anti-sticking raised line is arranged on one side, close to an eyelid, of the periocular patch; a plurality of air holes are formed in the surface of the periorbital patch, the periorbital patch is provided with at least one contraction assembly, and the contraction assembly is clamped between every two adjacent air holes. According to the periocular postoperative care patch, the periocular patch is used for conducting full-circumference patch protection on the periocular, the periocular postoperative care patch can be applied to periocular operations such as pouch removal, periocular skin can be protected more sufficiently and comfortably, and wound recovery is promoted.
Owner:CHENGDU HIGH TECH MILAN BAIYU MEDICAL BEAUTY HOSPITAL CO LTD

Glaucoma drainage tube with double drainage discs

The utility model relates to a glaucoma drainage tube with double drainage discs, which belongs to the technical field of medical artificial implants and comprises a drainage tube body, a drainage mechanism is arranged on the right side of the drainage tube body and comprises a fixing structure fixedly mounted on the outer side of the drainage tube, and the double-layer drainage discs are fixedly mounted on the right side of the fixing structure. The glaucoma drainage tube with the double drainage discs can be easily implanted into an anterior chamber corner during an operation, can be accurately butted with an aqueous fluid generation source, ensures that aqueous fluid flows in without hindrance, lays a solid foundation for subsequent drainage, can be tightly attached to a sclera by virtue of the characteristics of the fixing structure, greatly reduces the displacement risk of an implant, ensures stable operation of a whole drainage system, and has a good application prospect. The upper drainage disc and the lower drainage disc cooperatively operate, the conjunctival sac is accurately opened, a stable filtering bubble is formed, the drainage groove matched with the drainage tube body in the drainage tube forms a smooth aqueous humor channel, aqueous humor drainage is accelerated, the supporting structure efficiently promotes aqueous humor diffusion between the two layers of drainage discs, and the drainage efficiency is comprehensively optimized.
Owner:XIAN PILLAR BIOSCI CO LTD

Conjunctival sac flushing device

ActiveCN223220706UBathing devicesConjunctivaConjunctival sac
The utility model relates to the technical field of medical instruments, and provides a conjunctival sac flushing device which comprises a base, a telescopic cylinder is fixedly arranged on the top face of the base, a connecting rod is fixedly arranged on the outer wall of one side of the upper end of the telescopic cylinder, a water receiving assembly is fixedly arranged at one end of the connecting rod, and the water receiving assembly comprises a connecting cylinder, a water receiver, a folding pipe and a drainage pipe. The outer wall of the connecting cylinder is connected with one end of a connecting rod, the top end of the connecting cylinder is provided with a water receiving device in an inserted mode, the bottom face of the connecting cylinder is provided with a folding pipe, and the lower end of the folding pipe is provided with a drainage pipe. Meanwhile, discomfort caused by the fact that flushing fluid leaks out of the water receiving device and wets clothes of a patient due to shaking of the water receiving device is avoided, a device for hanging bagged normal saline for flushing is integrated, the working efficiency of medical staff is improved, and pain of the patient is relieved.
Owner:靖西市人民医院

Ophthalmic conjunctival sac flushing device

ActiveCN119523795BBathing devicesConjunctivaConjunctival sac
The present invention relates to the technical field of conjunctival sac irrigation, and discloses an ophthalmic conjunctival sac irrigation device, which realizes simultaneous adjustment of the upper and lower heights and lateral positions of a mounting block and a water receiver by arranging an adjustment component, and the fixing method is relatively simple, convenient for an operator to use, improves adjustment efficiency, and facilitates subsequent irrigation operations; by arranging a limit component, it is possible to prevent plate body 1 from being separated from plate body 2 when it slides back and forth, and at the same time, the limit on plate body 1 can be cancelled when it needs to be disassembled, thereby facilitating maintenance and care; by arranging a transmission component, it is possible to realize connection and separation of plate body 1 and plate body 2 by rotating the adjustment rod alone, forming a linkage effect, and improving practicality; by arranging a sliding component, it is possible to adjust the positions of the mounting block and the water receiver, and automatically change the position of the shaping rod while adjusting the positions of the mounting block and the water receiver, thereby improving practicality.
Owner:THE THIRD MEDICAL CENT OF THE CHINESE PEOPLES LIBERATION ARMY GENERAL HOSPITAL

Conjunctival sac flushing and liquid collecting device

ActiveCN223504528UBathing devicesConjunctivaConjunctival sac
The utility model discloses a conjunctival sac flushing and liquid collecting device, which relates to the technical field of medical instruments and comprises a liquid collecting bag, a sticking strip and a suspension bracket, the liquid collecting bag is in an inverted cone shape, and the upper end of the liquid collecting bag is open and used for receiving flushing liquid. The pasting strip is arranged on the upper edge of the liquid collecting bag and used for being pasted on the cheek skin on the affected eye side; the upper edge of the liquid collecting bag is connected to the hanging frame so that the liquid collecting bag can be kept in an open state. The lower end of the liquid collecting bag is connected with a flow guide pipe, the suspension frame comprises a lifting rod, two suspension arms and a liquid collecting box serving as a base, the flow guide pipe is communicated with the liquid collecting box, the lifting rod is in a T shape, the lower end of the lifting rod is fixed to the upper end of the liquid collecting box, the two suspension arms are hinged to the two sides of the upper end of the lifting rod respectively, and the liquid collecting bag is arranged between the suspension arms on the two sides. And the upper edge of the liquid collecting bag is connected to the suspension arm. The liquid collecting bag does not need to be held by hand, and flushing liquid can be stably received.
Owner:XIANGZHOU COUNTY PEOPLES HOSPITAL (GENERAL HOSPITAL OF XIANGZHOU COUNTY PUBLIC HOSPITAL)

Sclera jacking training teaching aid

The utility model relates to the technical field of training teaching aids, in particular to a sclera jacking and pressing training teaching aid, which comprises a head model, a main control board, a silica gel eyeball model, a Bluetooth module, a voice module and a USB (universal serial bus) charging port, and is provided with a structure of a head, eye sockets, eyelids, conjunctival sacs and eyeballs, so that the model is closer to a real human eye structure; according to the simulation operation teaching aid, the jacking effect can be sensed in real time, a prompt tone can be given out, final evaluation can be made, a wide-area fundus photograph of a real case can be mapped into a retina 3D printing model, a vivid crack-derived retina shedding simulation operation teaching aid is achieved, meanwhile, a virtual eyeball is simulated at a mobile phone or a computer end, the jacking position, range and force are synchronously reflected, and the simulation operation teaching aid can be used for simulating the retina. The sclera jacking and pressing teaching aid is a multimedia physical teaching aid which combines visual virtual guidance and force and position perception, enables an operator to feel more vivid operation and more real feeling, obtains intelligent guidance of a computer, and quickly masters the sclera jacking and pressing technology in an operation.
Owner:粤北人民医院

Application of 2, 4-dihydroxy-6-methoxyacetophenone in preparation of medicine for treating lacrimal gland secretion dysfunction related diseases

The application is a divisional application of 2025116336025, the invention provides an application of 2, 4-dihydroxy-6-methoxyacetophenone in preparation of a medicine for treating lacrimal gland secretion dysfunction related diseases, a lacrimal gland dysfunction dry eye mouse model is constructed in the application, and liposome entrapped 2, 4-dihydroxy-6-methoxyacetophenone is adopted for intervention, so that the medicine for treating lacrimal gland secretion dysfunction related diseases is obtained. Experimental results show that the ocular surface function and structure of a model animal are remarkably improved through treatment of 2, 4-dihydroxy-6-methoxyacetophenone, the cornea sodium fluorescein staining score of a mouse in a 2, 4-dihydroxy-6-methoxyacetophenone treatment group is remarkably reduced, and cornea epithelium injury is effectively repaired; the epithelial structure in the cornea tissue tends to be complete, and inflammatory cell infiltration of a matrix layer is obviously relieved; the density of goblet cells in the conjunctiva is obviously increased, which indicates that the secretion function of the mucous layer on the ocular surface is recovered. The treatment of 2, 4-dihydroxy-6-methoxyacetophenone has an improvement trend on tear film rupture time and tear secretion amount, which indicates that the 2, 4-dihydroxy-6-methoxyacetophenone has a potential effect in the aspects of maintaining tear film stability and promoting basic tear secretion.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV

Phacoemulsification aspiration sleeve for intraocular and extraocular penetration and perfusion confirmation of glaucoma tube surgery

ActiveKR102991524B1ConjunctivaAqueous humor
The present invention relates to an ophthalmic ultrasonic emulsification sleeve for confirming intraocular and extraocular penetration and perfusion, which allows determining whether aqueous humor communication between the inside and outside of the eye is smooth through a microtube implanted in the eye during glaucoma tube surgery. The sleeve is characterized by having a rigid branch tube made of a material harder than a sleeve made of a soft material, provided in a perfusion port that allows the injection of a balance salt solution into the eye, and with the branch tube connected to the perfusion port, the tip of the branch tube protrudes further than the tip of the Paco tip, and the end of the microtube inside the eye is connected to the tip of the branch tube, so that the establishment of aqueous humor communication of the microtube can be quickly and accurately and sensorially confirmed based on the pattern of pressure change in the conjunctival area and surrounding blood flow change that occurs when the balance salt solution leaks out of the eye.
Owner:THE CATHOLIC UNIV OF KOREA IND ACADEMIC COOP FOUND

Frameless amniotic membrane mirror device, manufacturing method and using method

The invention relates to the technical field of medical instruments, in particular to a frameless amniotic membrane mirror device, a manufacturing method and a using method, and the frameless amniotic membrane mirror device comprises an amniotic membrane tissue layer and a biocompatible thin film layer formed by spraying a mixed solution of polymethyl acrylate and polyvinyl alcohol; the overall diameter of the device is 14 mm, the rise of the device is 6.2 + / -0.1 mm, and the device can be directly implanted into the ocular surface to cover the cornea without a frame support. The manufacturing method comprises the steps of amniotic membrane treatment, model eye forming, mixed solution preparation, membrane spraying and forming, trimming and sterilization. The application method relates to implantation after surface anesthesia, fitting observation and subsequent taking-out. Through the frameless conformal fitting design, the problems that an existing framed amniotic membrane mirror is displaced and cannot be worn by a patient with strong foreign body sensation and shallow conjunctival sac are solved, and meanwhile secondary trauma of a suture operation is avoided. And the residual film after the amniotic membrane is dissolved can continuously provide protection, and the amniotic membrane has the advantages of good fitness, high patient comfort, simplicity and convenience in operation and good safety.
Owner:JINAN SECOND PEOPLES HOSPITAL

Novel sticking type conjunctival sac flushing water receiving bag

ActiveCN224039602UBathing devicesSuction devicesConjunctivaConjunctival sac
The utility model relates to the field of medical instruments, in particular to a novel adhesive type conjunctival sac flushing water receiving bag which comprises a plastic protective film. The drainage bag and the drainage tube are further included, the plastic protective film is used for being pasted and covering the eyes, and the drainage bag used for collecting flushing fluid is fixedly connected to the right side of the plastic protective film; according to the utility model, the fitting degree with the eyes can be increased by arranging the plastic protective film which is made of the elastic material and is fitted with the eye curve design, and the drainage bag with the drainage tube is arranged on the right side of the plastic protective film and can be used for discharging waste water from the drainage tube, so that the eye washing time of an operator can be shortened without pouring liquid for many times; the labor intensity of nurses is relieved, the arc-shaped flow guide plate is arranged on the plastic protective film, flushing fluid can be guided to flow into the drainage bag, the risks of flushing fluid splashing and pollution can be reduced, the water level condition in the drainage bag can be monitored in real time through the water level sensor arranged on the drainage bag, and waste flushing fluid is prevented from overflowing.
Owner:SHANTOU UNIV·CHINESE UNIV OF HONG KONG JOINT SHANTOU INT OPHTHALMOLOGY CENT

Ocular surface microbial marker combination for diagnosing diabetes or diabetic retinopathy and application thereof

The invention discloses an ocular surface microbial marker combination for diagnosing diabetes or diabetic retinopathy and application of the ocular surface microbial marker combination. According to the invention, 10 ocular surface microorganisms obviously related to DM and DR are respectively screened, and DM and DR can be diagnosed by detecting the abundance of the microorganisms. The method belongs to a non-invasive technology, has the advantages of being convenient to detect and high in accuracy, and can be effectively applied to diagnosis of DM and DR. A classifier is generated according to the relative abundance of 10 microorganisms in the conjunctival sac swab of a subject, and in DM and non-DM control groups, the area AUC under the ROC curve of the classifier is 0.975, the sensitivity is 87.5%, and the specificity is 96.4%; in the DR and the DR group, the area AUC under the ROC curve of the classifier is 0.902, the sensitivity is 93.5%, and the specificity is 75.8%.
Owner:JIANGNAN UNIV

Application of biomarker detection reagent in preparation of xerophthalmia diagnosis and typing detection reagent

According to the application of a reagent for detecting the biomarker in preparation of a xerophthalmia diagnosis and typing detection reagent, the galectin-9 plays an important role in the occurrence and development process of the xerophthalmia, the expression level of the galectin-9 has a certain correlation with the severity of the xerophthalmia, and the galectin-9 is expected to be used as the biomarker for diagnosis and treatment of the xerophthalmia and can be used for preparing the xerophthalmia diagnosis and typing detection reagent. By detecting the expression condition of Galectin-9 in tears, early and accurate diagnosis of the dry eye and quantitative evaluation of the disease degree are achieved, in addition, Galectin-9 expressed on T cells plays an important role in immune inflammation of the dry eye, ocular surface damage of the dry eye can be relieved by locally intervening Galectin-9 through conjunctiva, and Galectin-9 serves as a novel potential target and has a good application prospect. A new way is opened up for diagnosis and treatment of xerophthalmia, a therapeutic drug or an intervention means developed for Galectin-9 can regulate immune response, inhibit inflammatory response, improve tear secretion and the like from the etiological level, and an existing xerophthalmia treatment mode is expected to be changed, so that the treatment effect is improved, the prognosis of a patient is improved, and the clinical application prospect is broad. The application prospect in the field of diagnosis and treatment of the xerophthalmia is wide, and a certain significance is achieved for improving the overall prevention and treatment level of the xerophthalmia.
Owner:THE EYE HOSPITAL OF WENZHOU MEDICAL UNIVERSITY

Oronasal conjunctival spray

A oronasal conjunctival spray may include a bottle for fluid and an applicator that may be screwable to the bottle. The spray applicator may include a nasal spray port for spraying fluid into a human nose, a conjunctival spray port for spraying fluid into a human eye, and an oral spray port for spraying fluid into a human oral cavity (mouth).
Owner:PARVIZ SHEIKH

An eye-care liquid for relieving eye fatigue and dryness and a preparation method thereof

This invention discloses an eye drop for relieving eye fatigue and dryness, and its preparation method, specifically belonging to the technical field of eye care. The eye drop contains a composition for relieving eye fatigue and dryness, excipients, and a solvent. The composition contains the following components in parts by weight: 20-30 parts of Rhodiola rosea root extract, 10-20 parts of Buddleja officinalis extract, 0.1-0.4 parts of ginger flower extract, and 0.4-0.5 parts of palmarosa extract. The key active ingredients in the composition provided by this invention—Rhodiola rosea root extract, Buddleja officinalis extract, ginger flower extract, and palmarosa extract—can accelerate the improvement of ocular secretions and alleviate lesions of the cornea, iris, and conjunctiva. Furthermore, the combined use of Rhodiola rosea root extract, Buddleja officinalis extract, ginger flower extract, and palmarosa extract has a synergistic effect, achieving multi-dimensional and multi-pathway maintenance of eye health. The eye drop provided by this invention has significant effects in relieving eye fatigue and dryness and improving eye comfort.
Owner:DR KUN HEALTH (SHENZHEN) GRP CO LTD

A conjunctival sac support sheet

ActiveCN224421242UConjunctivaConjunctival sac
This utility model relates to a conjunctival sac support sheet, comprising a light-transmitting support sheet body, the support sheet body having opposing outer and inner surfaces, and a plurality of first drainage holes provided on the support sheet body, the first drainage holes penetrating the support sheet body along the thickness direction and located in the edge region of the support sheet body. The first drainage holes not only have a stronger drainage function, but can also be used for suture fixation, allowing doctors to perform suture surgery to fix the support sheet in the conjunctival sac and prevent accidental dislodgement.
Owner:SHANGHAI DEFANG CLINIC CO LTD +1

Shunt for fibrous encapsulation in glaucoma patients

This disclosure relates to a shunt for fibrous encapsulation of glaucoma patients which lowers intraocular pressure by penetrating a fibrous encapsulation of a bleb formed between a sclera and a conjunctiva and draining aqueous humor within the bleb to subconjunctival.
Owner:SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Ocular therapy modes and systems

Methods, systems and apparatuses for delivering electrical or other therapy in the vicinity of the eye. One or more electrodes are positioned on or near the eye, such as contacting the superior or inferior eyelids, on the conjunctiva or medial or lateral canthus, on or inside the nose, or on the forehead. A remote or return electrode is optionally positioned elsewhere on the patient on the torso, neck, back, a limb, an extremity, on the back or side of the head, or near the ear, mandible or temple. A variety of pulse generator positions and support apparatuses are disclosed as well. The pulse generator is used to deliver one or more of therapy or diagnostic electrical pulses to the patient to address a condition of the eye.
Owner:I LUMEN SCI INC

Application of thalidomide in preparation of medicine for preventing or treating scar of conjunctival filtration vesicles after glaucoma filtration

The invention belongs to the technical field of biological medicines, and particularly relates to application of thalidomide in preparation of a prevention medicine or a treatment medicine for scar of conjunctival filtration vesicles after a glaucoma filtration operation. The thalidomide in the medicine disclosed by the invention can inhibit the cell activity of HTF in a concentration-dependent manner, prolong the survival time of filtration vesicles, and provide a medicine for resisting the scarring of the conjunctival filtration vesicles after the glaucoma filtration operation, which is satisfactory in curative effect and safe in application, so that the medicine can be used as a substitute for 5-FU and MMC.
Owner:SECOND AFFILIATED HOSPITAL OF COLLEGE OF MEDICINEOF XIAN JIAOTONG UNIV

Traditional Chinese medicine composition for preventing and treating ocular surface injury caused by xerophthalmia and application of traditional Chinese medicine composition

The invention relates to a traditional Chinese medicine composition for preventing and treating ocular surface injury caused by xerophthalmia and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-40 parts of spica prunellae, 20-40 parts of radix astragali, 5-25 parts of rhizoma polygonati, 5-25 parts of folium mori and 5-25 parts of fructus crataegi. Compared with the prior art, the traditional Chinese medicine composition disclosed by the invention consists of five medicinal and edible Chinese herbal medicines, is simple and convenient to take, safe and free from side effects, and can be popularized and used as a medicine for preventing and treating xerophthalmia. The traditional Chinese medicine composition disclosed by the invention can be used for remarkably inhibiting the corneal injury related to the xerophthalmia, maintaining the number of conjunctival goblet cells and providing new treatment for relieving the ocular surface injury of the xerophthalmia.
Owner:YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE

Training method of keratitis grading model fusing focus and complication image blocks

The invention provides a training method of a keratitis grading model fusing focus and complication image blocks, and relates to the field of artificial intelligence, and the method comprises the steps: collecting a plurality of slit lamp image samples; for each slit lamp image sample, identifying a cornea region and a conjunctiva region in the slit lamp image sample by using an image positioning algorithm; randomly cutting at least one first image block in each of upper, lower, left and right boundary areas of the conjunctiva area; randomly cutting at least one second image block in the cornea area; inputting the first image blocks and the second image blocks into a DenseNet121 model in sequence to obtain image features of the image blocks; cascading the image features to obtain a first cascading feature; performing dimension reduction on the first cascade feature by using a PCA algorithm to obtain a first dimension reduction feature; and performing iterative training on the cornea classifier based on the first dimension reduction feature until the cornea classifier converges. According to the method, the performance of the keratitis grading model and the keratitis grading accuracy are improved.
Owner:XIAN UNIV OF POSTS & TELECOMM

Eye drop instillation assist device

The invention belongs to the technical field of medical auxiliary instruments, and particularly relates to an eyedrop instillation assist device which comprises a negative pressure adsorption base, a pupil calibrator and a liquid medicine squeezer. A negative pressure adsorption base, a pupil calibrator and a liquid medicine squeezer are arranged, the negative pressure adsorption base comprises an adsorption long arm, an upper suction cup, a lower suction cup and a squeezing air bag, the pupil calibrator comprises a sliding assembly and a calibration assembly, and the liquid medicine squeezer is provided with a squeezing support, a magnetic suction clamping nozzle, a manual squeezing arm and a linked eyelid supporting structure. By matching with components such as clamping teeth and a damping spring, a series of problems that the hand is easy to shake, the instillation position is inaccurate, liquid medicine is wasted, a bottle opening of a medicine bottle is easy to touch eyes to cause secondary injury, eyelids shield conjunctival sacs, the adaptability and universality of the device are poor, the extrusion force is non-uniform, the supporting is uncomfortable, the arm is soreness and swollen after long-term operation, the device is easy to shift and the like when the patient holds the device for instillation are solved; the effects that instillation is stable and accurate, operation is convenient, fast and safe, and different patients and medicine bottle specifications are adapted are achieved.
Owner:PEACE HOSPITAL AFFILIATED TO CHANGZHI MEDICAL COLLEGE

Nursing trolley for flushing conjunctival sac

The invention provides a conjunctival sac flushing nursing trolley which comprises a movable support, a headrest, a collecting barrel and an eye washing basin, the headrest is connected to the movable support through a first adjusting assembly, the first adjusting assembly is used for adjusting the position of the headrest in the horizontal direction of the movable support, the collecting barrel is detachably connected to the movable support, and the collecting barrel is detachably connected to the eye washing basin. The eye washing basin is connected to the movable support through a second adjusting assembly, the second adjusting assembly is used for adjusting the position of the eye washing basin in the vertical direction of the movable support, and the eye washing basin communicates with the collecting barrel. According to the device, the horizontal position of the headrest on the movable support is adjusted through the first adjusting assembly, and then the vertical position of the eye washing basin on the movable support is adjusted through the second adjusting assembly, so that when the head of a patient is placed on the headrest, the eye washing basin can be attached to the face, washing waste water can flow into the collecting barrel, and repeated pouring is not needed.
Owner:SHANTOU UNIV·CHINESE UNIV OF HONG KONG JOINT SHANTOU INT OPHTHALMOLOGY CENT

Ophthalmic compositions comprising F6H8

The present disclosure provides a method of treating keratoconjunctivitis sicca and / or meibomian gland dysfunction using an ophthalmic composition comprising a semifluorinated alkane, the method providing enrichment of the ophthalmic tissue for a semifluorinated alkane, and optionally delayed release of semi-fluorinated alkanes from enriched ocular tissue to the surface of cornea and / or conjunctiva and / or to meibomian glands.
Owner:NOVALIQ GMBH

Traditional Chinese medicine eye pad compound essential oil for treating xerophthalmia and preparation method thereof

The invention discloses traditional Chinese medicine eye pad compound essential oil for treating xerophthalmia and a preparation method of the traditional Chinese medicine eye pad compound essential oil. The essential oil is prepared from 10-15 parts of butterflybush flower essential oil, 10-15 parts of chrysanthemum essential oil, 10-15 parts of radix salviae miltiorrhizae essential oil, 3-5 parts of fructus lycii essential oil, 3-5 parts of rose essential oil, 3-5 parts of honeysuckle essential oil, 1-3 parts of peppermint oil, 1-3 parts of jojoba oil, 1-3 parts of sweet almond oil, 10-19 parts of penetration enhancer and 600 parts of purified water. The traditional Chinese medicine composition is based on traditional Chinese medicine components and is combined with the modern medicine theory, tests prove that the tear secretion amount can be increased, the pathological change of conjunctival tissues can be well improved, and the xerophthalmia can be prevented and treated.
Owner:ZHENGZHOU XINSHIMING SCI & TECH ENG CO