400 results about "Extended time" patented technology

An online auction system comprising a preliminary bidding portion and a virtual auction portion is disclosed herein. The preliminary bidding portion allows bidders to access auction items and input bids during a preestablished extended period of time. After the preliminary bidding portion concludes, the virtual auction portion provides bidders the opportunity to input bids on each item consecutively and individually from the preliminary auction portion in a manner similar to a conventional live auction. During the virtual auction portion, bidders are provided with a countdown to encourage further bidding before the previous bid becomes final. After each new bid is inputted, the countdown is reinitiated. The countdown is reinitiated until no new bids are input. An alert system notifies bidders that a particular item of interest is about to be offered for bid as part of the virtual auction portion. The system also provides bidders means for inputting proxy bids.

Exemplary systems and methods for content monitoring are provided. An exemplary content monitor comprises a plug-in application configured to initiate the monitoring of a network for one or more parameters over an extended time period. A mechanism is provided for notifying users about content monitoring results immediately after the one or more parameters are found on the network. Exemplary methods of the content monitor include a method for content monitoring comprising the entering of one or more parameters and monitoring the network for the one or more parameters over an extended time period.

A server includes volatile and non-volatile memories for storing messages received from a client device. A message reception module of the server stores a message received from a first client device in the volatile memory for an extended time period based on an indicator included in the message. The message reception module deletes the message from the volatile memory based on detection of a triggering event or stores the message in the non-volatile memory based on not detecting the triggering event before the extended time period has expired. The triggering event may include the message having been read by all specified recipients of the message. The indicator may be included in the message based on a relationship of the message to other messages. The message including the indicator may be related to other messages as part of a same conversation that has been determined to be suitable for short-term storage.

A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side. Each of the openings on the first side can be connected to each of the openings on the second side with the plurality of interconnecting channels, such that the rate of release of the therapeutic agent can be substantially maintained when one or more of the openings is blocked, for example with particles, cells, bacteria or tissue when the device is implanted for an extended time. The length of the channels extending from the first side to the second side may comprise an effective length greater than a distance across the porous structure from the first side to the second side. The therapeutic device many comprise an expandable retention structure and an expandable reservoir, such that the device can be delivered from a lumen of a delivery device and expand when positioned in the patient. The therapeutic device may comprises a penetrable barrier to inject therapeutic agent into the device when implanted in the patient.

Systems are disclosed herein that allow a participant to be associated with an avatar and receive a transmission from the participant in response to a participant activated transmission. The transmission can include a participant selectable and time delayed mood and / or activity command which can be associated with a user configurable command to avatar activity conversion table. The associated avatar activity table can provide control signal to the VU system controlling the participant's avatar for extended time periods, where the activity commands allow the avatar to exhibit a mood and to conduct an activity. The preconfigured time controlled activity commands allow the user to control their avatar without being actively engaged in a session with a virtual universe client or logged on and the control configuration can be set up such that a single mood / activity control signal can initiate moods and activities that occur over an extended period of time.

The invention relates to TGF-β blocking agent-treated HSC compositions and methods comprising the same. The TGF-β blocking agent-treated stem cells are viable for an extended time in culture without replication or differentiation and upon transfer to appropriate conditions are capable of long term hematopoietic reconstitution.

A method and system for tracking a rail car having an on-board communication system including a location determining system and a transceiver for receiving and transmitting rail car data. The communication system including a processor responsive to an executable program for enabling operation of the transceiver to transmit rail car data during a reporting event and having a memory for storing data and instructions. The processor memory includes a remotely addressable software database accessible by the executable program for establishing a reporting event in response to at least one of a selected time, a change in geographical location, an extended time in a geographical location, an approach to a specified geographical location, a coupling / decoupling of the rail car with a particular locomotive and a command to report. The rail car includes an AEI reader attached to the rail car for reading AEI tags on other rail vehicles passing by the reader, the reader being in communication with the rail car message system for transmitting data indicating at least a location of the other rail vehicles.

A packaged meal is provided in the form of a kit arrangement which is formulated and prepared for storage under refrigerated, non-frozen conditions for extended time periods within retail store showcase coolers. The kit includes a compartmentalized, hermetically sealed package, with a refrigerated baked flour-containing component or dough component within an overpouch which is sealed or unsealed and positioned within one of the compartments and being specially formulated to maintain its freshness and retarding staling during extended refrigerated storage within the hermetically sealed package. At least the compartment within which baked component is sealed has an anti-fogging agent component which further assists in maintaining freshness and retarding staling under even refrigerated, non-frozen conditions.

The present invention provides time released markers for use with single reservoir and commingled wells. The invention accomplishes the time release of markers by coating or encapsulating marker particles or by coating a proppant which has been saturated with a marker. After coating or encapsulation, the marker is injected into a well as is known in the art. The marker remains in the well. The marker is released after an elapsed of time. The elapsed time can be in a wide range. After the elapsed time, production is taken from the well and tested for the presence of the marker. Various types of known analyses can be performed to test for the presence and concentration of the marker in the production fluid. The concentration of the marker in the production fluid allows the apportioning of production from the reservoir. In addition, different markers may be added to each zone within a reservoir where each marker has a different elapsed time increment. The zones can be any different layer or area in the reservoir such as different strata or layer of rock, limestone or sand. Differing marker combinations allow contribution from different zones to be monitored over an extended time.

A respirator 10 that has a mask body 14 and a malleable nose clip 12. The mask body 14 is adapted to fit at least over the nose and mouth of a person to define an interior gas space that is separate from the exterior gas space. The mask body 14 has the nose clip 12 secured to it and can include at least one layer of filter media 20. The malleable nose clip 12 comprises a semi-crystalline polymeric material that has an integrated diffraction intensity ratio of at least about 2.0. The nose clip 12 can be deformed into a desired configuration that enables the mask body 14 to maintain a snug fit over a person's nose when the respirator is worn for extended time periods. Because the nose clip 12 does not need to contain metal, the whole respirator 10 can be easily processed as waste in an incinerator when its service has ended.

Systems are disclosed herein that allow a participant to be associated with an avatar and receive a transmission from the participant in response to a participant activated transmission. The transmission can include a participant selectable and time delayed mood and / or activity command which can be associated with a user configurable command to avatar activity conversion table. The associated avatar activity table can provide control signal to the VU system controlling the participant's avatar for extended time periods, where the activity commands allow the avatar to exhibit a mood and to conduct an activity. The preconfigured time controlled activity commands allow the user to control their avatar without being actively engaged in a session with a virtual universe client or logged on and the control configuration can be set up such that a single mood / activity control signal can initiate moods and activities that occur over an extended period of time.

A method for the administration of a composition that augments the acidity of gastric fluid such that intra-gastric gelation of the polysaccharide:acid soluble multivalent cation formulation is initiated independent of endogenous acid secretion. The composition includes:(a) at least one of a polysaccharide, modified polysaccharide, or polysaccharide salt, each capable of ionotropic gelation, (b) at least one source of multivalent cations capable of solubilization at an acidic pH, and (c) at least one acid component capable of providing a controlled release of protons sufficient to solubilize the multivalent cations. The composition is capable of hydrating in aqueous media and subsequently forming a gel in a stomach when ingested, which gel resists peristaltic forces and remains in the stomach for an extended time. Also disclosed are edible compositions including this composition, as well as methods of inducing a satiety effect and providing controlled release of various components employing the composition of the invention.

A first tube (3) and second tube (7) for guiding aqueous humor to the exterior of the eye are connected to each other in the vicinity of a surface of conjunctiva (14) via a first joint (5) and second joint (6). A filter part (9) provided to prevent reflux infection from the exterior to interior of the eye is connected to the second tube (7) via a third tube (8) positioned inside a lower lacrimal canaliculus (23). This enables an aqueous humor drainage implant (1) to be positioned in the eye and the exterior of the conjunctiva with reduced invasiveness. With the aqueous humor drainage implant for glaucoma treatment, the aqueous humor in the eye can be drained to the exterior of the conjunctiva while preventing reflux infection at the viral level, and the intraocular pressure reducing effect can be sustained for extended time periods over the lifespan of the patient. Further, the aqueous humor drainage implant can be readily positioned with reduced surgical invasiveness, while posing no danger of damaging the eye or nasolacrimal duct after the installation.

A silver and silver alloy plating bath, includes (A) a soluble salt, having a silver salt or a mixture of a silver salt and a salt of a metal such as tin, bismuth, indium, lead, and the like; and (B) a particular aliphatic sulfide compound, such as thiobis(diethyleneglycol), dithiobis(triglycerol), 3,3′-thiodipropanol, thiodiglycerin, 3,6-dithiooctane-1,8-diol, and the like, which contain at least one or more of an ether oxygen atom, a 1-hydroxypropyl group, a hydroxypropylene group, or two or more of a sulfide bond in the molecule, and not containing a basic nitrogen atom. Compared to baths containing aliphatic monosulfide compounds, such as thiodiglycol or beta-thiodiglycol, which do not contain an ether oxygen atom, 1-hydroxypropyl group, a hydroxypropylene group, or two or more of a sulfide bond in the molecule, by having these particular compounds, the plating bath of the present invention has excellent stability over extended time, excellent co-deposition of silver and various metals, and excellent appearance of the electrodeposition coating.

The present invention provides biocompatible, low molecular weight nanoparticulate formulations that are designed to retain and deliver therapeutics over an extended time course. The therapeutic may be conjugated or adsorbed to the periphery of the corona or conjugated to a core polymer. The nanoparticles comprise targeting ligands also conjugated or adsorbed to the periphery of the corona and / or a contrast agent in the core of the nanoparticle. As such, methods of selective targeting and / or methods of noninvasive imaging using bioluminescence and / or magnetic resonance imaging. Also provided are methods of delivering to and, optionally, imaging of a cell or tissue. Further provided are methods of producing the nanoparticles in batch or continuous mode via simple mixing or laminar flow.

There is provided a composition comprising at least one mucoadhesive polymer that is capable of forming a hydrogel and at one least water soluble polymer, and one or more enzymes, microorganisms, or antibodies. The formulation forms a hydrogel in aqueous solution that has mucoadhesive properties and that is capable of releasing the enzymes, microorganisms, or antibodies over an extended period of time and / or of entrapping enzymes, microorganisms, or antibodies within the hydrogel that is active for an extended time.

Controlled release of hydrophobic bioactive substances in vivo over an extended time period and without "bursts" of drug release is achieved using a liquid polymeric composition including a polymer such as poly(lactide-co-glycolide) copolymer in a mixture of hydrophilic and lipophilic solvents.

A sustained release composition comprising expanded thermoplastic microspheres, an active agent, and an optional release retardant is disclosed. The composition has an improved ability to stabilize and release the active agent over an extended time period.

The present invention provides a series of biocompatible, nanoparticulate formulations that are designed to retain and deliver peptides such as anti-angiogenic factors over an extended time course. The nanoparticles can be targeted to a cell or tissue by targeting ligands crosslinked or conjugated to the corona of the nanoparticles. In addition to selective targeting, the nanoparticles also may perform noninvasive imaging using bioluminescence and / or magnetic resonance imaging via a contrast agent in the core of the nanoparticle. Also provided are methods of delivering to and, optionally, imaging of a cell or tissue. Furthermore, methods of producing the nanoparticles in batch or continous mode via simple mixing or micromixing.

Systems and methods for determining a stability of a blood glucose concentration of a patient are provided. The system comprises a processor that may be programmed to receive blood glucose concentration test results each taken from the patient at a different time over a time period and to compute a time-averaged glucose parameter indicative of blood glucose concentration control over the time period. In addition, the processor may be programmed to compute a virtual blood hemoglobin parameter through a simulated measurement of a blood hemoglobin, the virtual blood hemoglobin parameter being indicative of blood glucose concentration control over an extended time period encompassing the time period. Further, the processor may be programmed to compute a lability factor parameter indicative of a variability in blood glucose concentration over the time period.

A pharmaceutical dosage form comprising non-steroidal-anti-inflammatory drugs, in particular propionic acid derivatives such as ibuprofen, along with a second active ingredient having a shorter therapeutically effective plasma concentration duration, such as phenylephrine, and methods of administering the same are provided. This method provides improved therapeutic effect, in particular pain relief along with decongestant relief, over extended time periods.

A method of distributing educational content over a network is disclosed. Educational content is divided into topics and the topics are split into smaller educational units. Professionals reviewing the material for accreditation purposes choose particular units to study and are subject to minimum and maximum time parameters. The partitioning of educational topics allows advertisers to deliver episodic advertising over an extended time period.

A sustained release composition comprising cellulose fibers, an active agent, and an optional release retardant is disclosed. The composition has an improved ability to stabilize and release the active agent over an extended time period.

A method and devices for localized delivery of a chemotherapeutic agent to solid tumors, wherein the agent does not cross the blood-brain barrier and is characterized by poor bioavailability and / or short half-lives in vivo, are described. The devices consist of reservoirs which release drug over an extended time period while at the same time preserving the bioactivity and bioavailability of the agent. In the most preferred embodiment, the device consists of biodegradable polymeric matrixes, although reservoirs can also be formulated from non-biodegradable polymers or reservoirs connected to implanted infusion pumps. The devices are implanted within or immediately adjacent the tumors to be treated or the site where they have been surgically removed. The examples demonstrate the efficacy of paclitaxel and camptothecin delivered in polymeric implants prepared by compression molding of biodegradable and non-biodegradable polymers, respectively. The results are highly statistically significant.

Controlled release of hydrophobic bioactive substances in vivo over an extended time period and without "bursts" of drug release is achieved using a liquid polymeric composition including a polymer such as poly(lactide-co-glycolide) copolymer in a mixture of hydrophilic and lipophilic solvents.

A method and apparatus enables advanced signal processing in a wireless local area network (WLAN). First and second WLAN transceivers are provided with advanced signal processing capabilities. A maximum interframe period between data and an acknowledgement is required by the WLAN for compatibility. A duration of the interframe period is shorter than a duration that is required to perform the advanced signal processing. The first WLAN transceiver transmits a header and data. A first data field in the header is specified that enables the advanced signal processing. A second data field is specified that defines a data time period and an extension time period. The first WLAN transceiver transmits data during the data time period and dummy data during the extension time period. The second WLAN transceiver receives the header and initiates receiver processing during the extension time period.

A wireless control system for a bicycle, comprising a first shift control unit for a component of a bicycle, the first control unit comprising a radio configured to receive control signals, wirelessly transmitted by a second control unit of the bicycle; the radio operable to receive the control signals only when the radio is operating in a listen mode; and a processor configured to: activate the listen mode of the radio for a first length of time; detect, with the radio, a noise level during the first length of time; and extend the activation of the listen mode for a first extended time period when the noise level achieves a noise level threshold.