75 results about "Ocular surgery" patented technology

Shape-stabilized collagen scaffolds and methods of obtaining such scaffolds are disclosed. Stroma can be harvested, for example, from human or porcine corneal stroma and shaped during excision or in a separate step after excision. Following shaping (and preferably decellularization), the excised stroma portion is subject to pressure, force or vacuum to reduce fluid content and then irradiated or otherwise treated to induce crosslinking of collagen chains or fibrils. In one embodiment, the scaffold can be compacted by removing some or all of the water from the scaffold, and rehydrating the scaffold in a controlled manner (e.g., in a mold or other confining space) such that the scaffold takes a desired compacted shape; and then crosslinking at least a portion of the scaffold to mechanically strengthen it and inhibit subsequent swelling. Various sources of energy can be employed to induce crosslinking of collagen including, for example, ultraviolet (UV) radiation. The scaffolds can also be selectively densified or patterned. The invention is particularly useful in forming stable lenticules of enhanced stiffness and sufficient optical clarity for intracorneal implantation in additive ocular surgery.

An ophthalmic system for visualization of interactions between ocular matter and a probe tip of a probe within or in contact with an ocular space of an eye includes: a visualization tool having a field of view that includes at least a portion of the ocular space of the eye where the probe tip interfaces with the ocular matter; and a stroboscopic illumination source configured to stroboscopically illuminate at least the portion of the field of view at an illumination frequency. A method of operating a stroboscopic illumination source during an ophthalmic surgical procedure includes: identifying an illumination source type of the stroboscopic illumination source; identifying a probe type; identifying a first procedure trigger; and operating the stroboscopic illumination source based on the probe type, the illumination source type, and the first procedure trigger.

A robotic system for performing an ocular surgery includes a robot and an electronic control unit (ECU). The robot includes an end-effector, six or more electric motors connected to or operable for moving six or more links and controllable via the ECU, and all-pose gravity compensation structure. A surgical tool is connected to the end-effector. The robot and surgical tool, in response to electronic control signals from the ECU, perform a surgical task on an eye during the ocular surgery. The ECU includes scaling logic operable for downscaling or limiting a tool force imparted to the eye by the surgical tool and / or a tool velocity of the surgical tool. All-pose gravity compensation minimizes a perceived weight of the surgical tool during the ocular surgery. The robotic system may include a surgeon-operated haptic device / master in which the robot acts as a slave device.

An arrangement applied to a simulator for surgical training in ophthalmology that is anatomically similar to the human eye, and has the purpose of training and qualification in ophthalmological surgical processes. An artificial cataract for use in simulators for surgical training in ophthalmology.

An ophthalmic surgical instrument for peeling a retinal membrane is provided. The ophthalmic surgical instrument includes a handle, an actuator mounted to the handle, a first loop, and a second loop. The first loop extends outwardly from the handle and comprises a first plurality of protruding features configured to create an internal limiting membrane (ILM) flap in an eye. The second loop extends outwardly from the handle, is positioned within the first loop, and is configured to grasp the ILM flap. The actuator is configured to move the second loop to engage the first loop to grasp the ILM flap.

In certain embodiments, an ophthalmic surgical system for viewing an eye includes an ophthalmic microscope and a laser device. The ophthalmic microscope receives light reflected or scattered backwards from within the vitreous of the eye in order to provide an image of an object within the vitreous. The ophthalmic microscope includes a slit illumination source (which includes a light source and an optical element), a spectral filter, and oculars. The slit illumination source illuminates the eye with light, where the light source provides the light, and the optical element directs the light into the eye. The spectral filter filters out red spectral components of the light. The oculars receive the light from the eye in order to provide the image of the object. The laser device generates a laser beam to direct towards the object within the eye.

A kit for ocular surgery includes a syringe comprising a needle having dimensions suitable for injecting an ophthalmic viscosurgical device OVD material to form an OVD in an eye for ocular surgery; a suitable amount of OVD material for forming the OVD loaded into the syringe; and instructions for suitable optical illumination to be used to observe the OVD, or a remaining portion thereof, at least one of during or after the ocular surgery based on a response of the OVD material to the optical illumination. The OVD material includes a polymer and at least one of a dye, a fluorophore, a luminophore, or a quantum dot conjugated to the polymer.

An ocular compression device with light directed through the sclera. The compression device may detachably house a lighting device that can be used to illuminate the eye area during ophthalmic surgery. Integrating the lighting device with the compression device during the procedure may reduce the number of hands required to perform the surgery. This may be particularly beneficial for ophthalmic surgery where the available surgical space is limited.

This invention discloses the application of low-concentration topical anesthetics in ophthalmic surgery, relating to the field of low-concentration topical anesthetic application technology, including the following specific application process: confirming the patient's basic surgical condition before administration; selecting anesthetic drugs and optimizing the administration concentration; performing administration according to the specific situation; real-time dynamic monitoring and adjustment of the administration dosage; gradually reducing the drug and transitioning to withdrawal. This invention improves drug safety and patient compliance while ensuring analgesic effects by optimizing anesthetic drug concentration and administration method. Furthermore, by using topical anesthetics at concentrations lower than conventional anesthetics for local administration after ophthalmic surgery, it can effectively relieve postoperative pain, discomfort, and foreign body sensation while significantly reducing toxic effects on corneal epithelial cells, reducing delayed corneal healing, dry eye, and corneal damage. It is effectively applicable to analgesia management after pterygium excision, refractive surgery, and other common ophthalmic surgeries, and has good clinical application value.

A system (10) and method (70) for quantifying light exposure of a patient's retina (25) during ophthalmic surgery. A light source (32) illuminates the patient's retina (25) with directional light (LL) during the surgery to produce an illuminated retina surface. A camera (36) collects image data (38) of the illuminated retina surface (25I). An electronic control unit, ECU (50), is in communication with the camera (36) and an indicator device (40), receives the image data (38), calculates a cumulative energy spectral density of the directional light (LL) incident on the retina (25), and performs a control action indicative of possible phototoxicity in response to the cumulative energy spectral density exceeding a phototoxicity threshold, the control action including enabling the indicator device (40). The illuminated retina surface (25I) can be divided into virtual zones (Z1, Z2), the ECU (50) mapping the cumulative energy spectral density to the illuminated retina surface (25I). Each of the optional zones (Z1, Z2) has a corresponding cumulative energy spectral density.

Devices and methods are disclosed for improved removal of cortical material. In certain embodiments, an ophthalmic surgical instrument includes a shaft having a distal end configured to be inserted into an eye of a patient toward a treatment area, and a projection located at the distal end of the shaft, the projection having a distal surface that extends at an angle to a longitudinal axis of the shaft, the distal surface configured to be positioned facing the treatment area during use of the ophthalmic surgical instrument. The projection is located on a tip or a sleeve of the ophthalmic surgical instrument.

The invention belongs to the technical field of ophthalmologic surgical instruments, and provides a posterior capsular membrane polisher in a cataract surgery in order to solve the problem that existing manual operation is low in accuracy. Comprising a head fixing module for fixing the head of a patient; the movable positioning module is arranged on the head fixing module and comprises up-down telescopic assemblies arranged on the two sides of the head fixing module, a longitudinal moving assembly and a transverse moving assembly are arranged on the up-down telescopic assemblies, and a polishing module mounting frame is arranged on the transverse moving assembly; the polishing head multifunctional integrated module comprises a supporting frame connected through a polishing module mounting frame, the supporting frame is provided with an eye periphery supporting rod and a micro-pressure induction push rod, the micro-pressure induction push rod is connected with a connecting plate, the connecting plate is connected with a polishing rod, and a polishing head is arranged in the polishing rod. By means of the integrated design, it can be guaranteed that the operation is completed through one-time polishing operation, errors caused by manual operation are avoided, previous tedious steps are omitted, the operation time is shortened, and the operation risk is reduced.

An ocular surgery visualization system has an ophthalmoscopic loupe that images a portion located within a patient's eye in an intermediate image plane. An image processing routine separates a first portion of an image of a target region in the imaging plane from a second portion of the image of the target region, the first portion being captured by an image sensor and resulting from an imaging beam path through the ophthalmoscopic loupe, the second portion being captured by the image sensor and resulting from an imaging beam path extending beyond the ophthalmoscopic loupe and being complementary to the first portion, so as to transform the first portion of the image of the target region into a mirror first portion by a congruence corresponding to a rotation of the first portion around an axis of rotation perpendicular to the image plane or by a congruence corresponding to a point mirror, and so as to combine the rotated or point mirror first portion and the second portion to form a target region composite image that is provided to an image display device.

Embodiments of the present disclosure provide a surgical instrument having a pressure sensor coupled to or adjacent to a distal end of the surgical instrument to achieve a direct intraocular pressure (IOP) reading of an eye. The surgical instrument may include a handheld device that is inserted into the eye to perform a surgical task.

The utility model belongs to the field of manufacturing of auxiliary elements of microscopes, and particularly relates to a non-contact type fundus wide-angle observation mirror which comprises an inverted image and positive image switching device, a bottom plate, a space position mechanical adjusting mechanism and a wide-angle lens placer, and the inverted image and positive image switching device is arranged on the upper surface of the bottom plate. A wide-angle lens placer is arranged on the lower surface of the bottom plate through a spatial position mechanical adjusting mechanism, a light inlet area is reserved at a light inlet of the inverted image and positive image switching device on the bottom plate, the position under the light inlet area is within the travel range where the spatial position mechanical adjusting mechanism drives the wide-angle lens placer to move, and a mounting hole is formed in the bottom plate. According to the non-contact type fundus wide-angle observation mirror, the mode that the inverted image and positive image switching device is arranged to be matched with the space position mechanical adjusting mechanism and the wide-angle lens placer is adopted, the non-contact type fundus wide-angle observation mirror is designed, and the problem that holes do not need to be punched in eyeballs of a patient to fix the wide-angle observation mirror during an ophthalmologic operation is solved.

The invention relates to the technical field of pharmaceutics, in particular to a monoclonal antibody preparation for inhibiting fibrosis after an eye operation and application. The anti-periostin humanized monoclonal antibody injection preparation provided by the invention is prepared from the following components: an anti-periostin humanized monoclonal antibody, a buffering agent, amino acid, polysorbate and trehalose. The preparation is stable in property. The biological activity is good, and the stimulation to eyeballs can be reduced.

A control apparatus for an ophthalmic surgical system includes a receiver module which received a signal containing at least one geometric size of a pupil of an eye to be treated at least at a first time during a surgical procedure on the eye, at which fluid is supplied to and / or removed from the eye to be treated on the basis of set values of fluidic parameters of a fluidic apparatus. An evaluation unit allows the signal with the geometric sizes of the pupil to be compared to a geometric reference size of the pupil. An output module outputs an output signal of the evaluation unit, which contains information in respect of the geometric size of the pupil and / or information in respect of the above comparison to a control unit of the ophthalmic surgical system.

Ophthalmic compositions including compatible solute components and / or polyanionic components are useful in treating eyes, for example, to relieve dry eye syndrome, to protect the eyes against hypertonic insult and / or the adverse effects of cationic species on the ocular surfaces of eyes and / or to facilitate recovery from eye surgery.

An ophthalmic surgical instrument for peeling a retinal membrane is provided. The ophthalmic surgical instrument includes a handle, an actuator mounted to the handle, a first loop, and a second loop. The first loop extends outwardly from the handle and comprises a first plurality of protruding features configured to create an internal limiting membrane (ILM) flap in an eye. The second loop extends outwardly from the handle, is positioned within the first loop, and is configured to grasp the ILM flap. The actuator is configured to move the second loop to engage the first loop to grasp the ILM flap.

The invention relates to an ophthalmic surgical system (1) for treating an eye (2), and to a method. The ophthalmic surgical system (1) comprises a pressure sensor (12) which determines pressure information describing at least a pressure exerted by a treatment fluid on the pressure sensor (12) and, in the event of a handpiece (9) or infusion element at least partially inserted into the eye (2), a pressure exerted on the pressure sensor (12) by an intraocular pressure of the eye (2). A time curve (30) of the pressure information is determined and analysed to ascertain whether a pressure information increase (31) can be detected in which the pressure information increases in stages from a first pressure information (32) to a second pressure information (33), wherein a pressure information difference (34) between the two items of pressure information (32, 33) is greater than a specified minimum value (36). If the pressure information increase (31) has been detected, patient eye height information (38) and / or intraocular pressure information (37) is determined and provided by applying an evaluation algorithm (42) to the first pressure information (32) and / or the second pressure information (33).

To improve the precision of ophthalmic surgical procedures by reducing corneal wrinkling, a patient interface for an ophthalmic system can include an attachment portion, configured to attach the patient interface to a distal end of the ophthalmic system; a contact portion, configured to dock the patient interface to an eye; and a contact element, coupled to the contact portion, configured to contact a surface of a cornea of the eye as part of the docking of the patient interface to the eye, and having a central portion with a central radius of curvature Rc and a peripheral portion with a peripheral radius of curvature Rp, wherein Rc is smaller than Rp.

This invention relates to the field of materials science and technology, and discloses the application of zwitterionic polymer injectable hydrogels as vitreous substitutes. Zwitterionic monomers selected from CBUIA, CBUTA, CBOH, CBMA, or MPC are dissolved in an aqueous phase, and polymerization is initiated by an initiator to obtain a hydrogel. After swelling equilibrium, the zwitterionic polymer injectable hydrogel is obtained. This invention uses initiator-initiated free radical polymerization of monomers and prepares physically cross-linked pure zwitterionic hydrogels through multi-hydrogen bond interactions or chain entanglement. The pure zwitterionic hydrogel with injectable properties is prepared through swelling equilibrium. It exhibits good biocompatibility, which is beneficial for improving the affinity of this zwitterionic polymer-based hydrogel vitreous substitute to the vitreous cavity, reducing adverse reactions after implantation. Furthermore, the preparation method is simple and the conditions are mild, making it more suitable for large-scale promotion and use as a vitreous substitute in ocular surgery, and it exhibits excellent biofouling resistance.

An apparatus is presented for attaching a lens to a micro-scope with an optical attachment. The apparatus includes the lens with one or more translational degrees of freedom such that the lens is configured to translate along one or more directions relative to the microscope and / or one or more rotational degrees of freedom such that the lens is configured to rotate about one or more rotational axes relative to the microscope. A system is also presented that includes the apparatus and the optical attachment. The optical attachment includes a lens arm and / or the viewing attachment configured to move the lens and the lens arm relative to the microscope. A method is also presented for using an optical attachment to position a hands-free lens relative to a microscope.

An ophthalmic system for visualizing interaction between an ocular matter and a probe tip of a probe within or in contact with an ocular space of an eye includes a visualization tool having a field of view that encompasses at least a portion of the ocular space of the eye at an interface of the probe tip and the ocular matter, and a stroboscopic illumination source configured to stroboscopically illuminate the at least the portion of the field of view at an illumination frequency. A method for operating a stroboscopic illumination source during an ophthalmic procedure includes identifying an illumination source type of the stroboscopic illumination source, identifying a probe type, identifying a first procedure trigger, and operating the stroboscopic illumination source based on the probe type, the illumination source type, and the first procedure trigger.

Disclosed herein are methods, devices, and systems for monitoring fluid outflow behavior of an eye of a subject, for example, during ocular surgery. Changes to intraocular pressure can reflect fluid outflow behavior. Fluid outflow behavior can be a critical factor in the successful outcome of a surgery and determining likelihood of post-operative side effects. Large fluctuations in intraocular pressure, ocular hypertension, and hypotony can be associated with vision loss or poor ocular health.

An adapter for a surgical hand piece with a single lumen work tip converts the handpiece to infusion / aspiration (I / A) cleanup of lens epithelial cells in the capsular bag of the eye a patient after phacoemulsification. The adapter is in the form of a sleeve whose proximal end is to be joined to the distal end of work tip. The sleeve also has at least one aspiration hole located toward the distal end of the sleeve.

The invention relates to an ophthalmic surgical handpiece (2) for treating a lens (31) of an eye (29), an ophthalmic surgical system (1), and a method. The handpiece (2) comprises a connecting piece (70) to which a needle (20) with a needle tip (21) is mounted and which is coupled to a vibration generation device (22); and the vibration generation device (22), which can excite the needle (20) to vibrate via the connecting piece (70). The handpiece (2) can be operated in a high-energy mode (42), in which the vibration components are excited at least by means of a first piezoelectric element (24), and in a low-energy mode (44), in which the vibration components are excited at least by means of a second piezoelectric element (23).Alternatively or additionally, the handpiece (2) can be operated in a pre-tensioning mode in which the first piezo element (24) and / or the second piezo element (23) is subjected to a pre-tension by controlling at least one piezo-based pre-tensioning device (35).