30results about "Eye implants" patented technology

A surgically implanted ocular optical array that can be used in both therapeutic and diagnostic applications is described. A device configured to be implanted in an eye includes: an imaging system that receives visible light incoming to the eye; optical source generating circuitry that generates an optical signal based on the light received by the imaging system; and an optical phased array (OPA) that generates and projects an image onto a retina of the eye in which the device is implanted, the image being based on the optical signal generated by the optical source generating circuitry.

This application relates to a femtosecond laser multi-degree-of-freedom personalized reshaping method and system for intracorneal implants, belonging to the field of femtosecond laser processing technology. Utilizing the cold processing characteristics of femtosecond lasers, the intracorneal implant is individually cut and ablated to obtain the desired three-dimensional corneal shape, precisely shaping the curvature, thickness, and contour of the lens to perfectly match the patient's corneal capsule or lesion area. By leveraging the nonlinear optical effect induced at the focal point of the femtosecond laser, the stromal collagen network in the weak areas corresponding to corneal expansion can be densified through laser processing, significantly improving the local elastic modulus and resistance to deformation. In areas requiring a smooth transition with the recipient cornea or adjustment of refractive power, controllable micropores or low-density areas can be induced, appropriately reducing local stiffness, thereby achieving a spatial gradient distribution of internal mechanical properties and customizing the overall mechanical behavior and morphological stability after implantation.

The present invention relates to a dental / medical device that comprises poly(dioxanone) (PDO or PDS), preferably has an absorbent synthetic film exhibiting a color from white to grey, and is applied in the medical and dental fields. The dental / medical device may have stem cells and graphene used for inducing tissue reconstruction and / or inducing tissue regeneration of bone defects and other connective tissues (such as gingiva, skin, cartilage, cornea, etc.). Further, the present invention relates to the use of the device for the related applications described above and a method for manufacturing the device.

This invention provides a method for encapsulating cells in microtissue. [Solution] A method for encapsulating cell microtissues includes coating a tissue scaffold stamp with an extracellular matrix compound. The method includes placing the tissue scaffold stamp on a thermoresponsive substrate and seeding a cell culture onto the tissue scaffold stamp. The cell culture forms cell patches that bind to the extracellular matrix compound. A monolayer boundary on the tissue scaffold stamp maintains expression for intercellular junctions, where the monolayer intercellular junctions are configured to express tension. The method includes removing the thermoresponsive substrate. The method includes folding the microtissue structure by suspending the microtissue in a solvent. The folded microtissue structure is recovered from the solvent and administered to a living organism.

Systems and methods for preparation of an implant and ab interno insertion of the implant into an eye of a patient including a tissue cartridge configured to receive and hold a patch of a material; a cutting device; and a delivery device. Related devices, systems, and methods are provided.

The present invention discloses compositions and methods for repair and reconstruction of defects and injuries to soft tissues. Some aspects of the disclosure provide methods for corneal reconstruction by applying an engineered bioadhesive, glycidyl methacrylate-substituted gelatin and a visible light activated photoinitiator in presence of visible light to the corneal defect.

The present invention provides a delivery device (10) for percutaneously implanting a medical implant (1) into a patient's tissue. The delivery device comprises a delivery sheath (12, 13, 53, 61, 62, 65, 66) configured to at least partially surround the medical implant and hold the medical implant for percutaneous delivery into the patient's tissue. The delivery device also comprises a power supply system (37) configured to supply power to the medical implant within the delivery sheath.

A method and a system of determining shape and appearance information of an ocular prosthesis for a patient, a computer program product and a conformer The invention relates to a method and a system of determining shape and appearance information of an ocular prosthesis (7) for a patient, comprising the steps of: - generating shape information for the ocular prosthesis (7), - determining the shape of the ocular prosthesis (7) depending on said shape information, - generating appearance information for the ocular prosthesis by capturing an image of a patient's eye, - fusing the shape and the appearance information, wherein the determination of the shape of the ocular prosthesis comprises - determining the shape based on a shape model being determined based on the shapes of existing prostheses or - determining the shape by generating shape information of an existing patient- specific prosthesis and transforming it into a uniform shape representation, and / or the generation of appearance information comprises performing at least one of - an inhomogeneous illumination correction and - a color characterization being performed using the same or similar viewing conditions as a color characterization of a device used for the manufacturing of the ocular prosthesis based on the appearance information. as well as a computer program product and a conformer (19). -

An intraocular implant that includes several lasers to produce several laser beams, where each laser beam has a different color. The implant also includes a diffraction grating to diffract the laser beams into a combined laser beam onto a retina of an eye when the implant is inside the eye, and a micro-electro-mechanical system (MEMS) scanner to move the combined laser beam over an area of the retina when the implant is inside the eye.

A system for treating an eye comprising a tissue stored within a lumen of an elongated cannula, the tissue comprises scleral, amniotic membrane, or acellular biomatrix tissue and having an elongated form factor. Related devices, systems, and methods are provided.

A drug delivery implant may include an implant body and a core comprising a pharmaceutical agent. The core can be located within the implant body that extends longitudinally and circumferentially around the core. The implant body can also define an aperture that exposes a first surface of the core. A method for treating a mammal to obtain a desired physiological or pharmacological effect by injecting such a drug delivery implant into a mammal in need of treatment is also disclosed.

The application discloses a composite artificial cornea and a preparation method thereof. The composite artificial cornea comprises a mirror column and a biological skirt. An annular gap is arranged on the inner side edge of the biological skirt. The outer side edge of the mirror column is embedded into the inside of the biological skirt along the gap, and the outer side edge of the mirror column is fixed in the gap through casting liquid. The application has the beneficial effects that: by arranging the annular gap on the inner side edge of the biological skirt, then embedding the outer side edge of the mirror column into the inside of the biological skirt along the gap, a interference fit structure is formed, preliminary fixation is formed between the mirror column and the gap, and the outer side edge of the mirror column is fixed in the gap through the casting liquid, so that the casting liquid can permeate and fill the gap, the mirror column and the biological skirt are connected into an integrated whole, secondary fixation is formed, the connection strength of the composite artificial cornea is improved, and the risk of the mirror column falling off is reduced.

To provide a system (for example, a retinal implant) that can function to transmit information to the user's brain. [Solution] In a modified form, the neural interface system (e.g., retinal implant, nerve implant, etc.) may include a display, controller, power supply, and / or any other suitable components. The system may be used with an external device that includes a communication element, a display-brain interface (e.g., a cell), and / or any other suitable components.

Provided is an intraocular implant delivery device, comprising a housing, a main control pull rod assembly, a slider assembly a striking assembly, a retracting needle turntable, and a push needle assembly. The main control pull rod assembly, the slider assembly, the striking assembly, and the retracting needle turntable are all arranged in the housing. A through hole is provided at a distal end of the housing, and a push needle of the push needle assembly passes through the through hole and extends to an outer side of the housing. The main control pull rod assembly, the slider assembly, and the striking assembly are each provided with an energy source capable of selectively releasing energy. The main control pull rod assembly is actuated by an operator through a button arranged on the housing, so that the energy source drives the main control pull rod assembly to move axially.

Disclosed here are several implementations directed to a system for precisely and consistently forming corneal plugs from donor corneas for transplantation and various other medical uses. Various implementations use an oscillating blade to ensure consistent incisions, tapered incisions, and / or grooves in the cornea in forming the corneal plugs.

An injector for an implant for an eye disease includes: a cannula comprising an inner space in which at least a part of the implant for an eye disease comprising a ripcord is to be accommodated, and an implant opening into which the implant for an eye disease is to be inserted; a handle part connected to the cannula and to be held by an operator; and a holder configured to be coupled to the handle part and comprising a receiving part in which the ripcord of the implant for an eye disease is to be accommodated. By the injector for an implant for an eye disease, because a ripcord inserted into a tube of the implant for an eye disease is appropriately fixed by being placed in the injector, problems such as the ripcord falling out of the tube, the implant being separated from the injector due to the ripcord, or the ripcord obstructing a surgeon's view during implant surgery may be prevented in advance.

Apparatus and methods are described including illumination equipment (300) configured to direct light into an eye of a subject. An optical device (100) is placed inside the subjects eye, the optical device including a Fabry Perot interferometer (106) comprising at least two mirrors (162, 164), the Fabry Perot interferometer (106) being configured such that a distance between the mirrors (162, 164) varies as an intraocular parameter of the subjects eye varies. A retroreflector (140) is configured such that light that is transmitted through the Fabry Perot interferometer (106) is automatically reflected out of the subjects eye. Readout equipment (400) is configured to detect the light that is reflected out of the subjects eye. Other applications are also described.

A method and device for reducing intraocular pressure in a patient. The method may comprise deploying administering a viscoelastic material into Schlemm's canal to open aqueous humor outflow pathways. The device is adapted to perform the method. The viscoelastic material may be configured to lower the intraocular pressure within the eye.

A keratoprosthesis (100), comprising a support (10) and a lens column (30), the lens column (30) comprising a body (31) and a collar (32). A middle part of the support (10) is provided with a mounting hole (10A), a hole wall of which being provided with an internal thread (111), and the outer peripheral wall of the collar (32) being provided with an external thread (321) fitting with the internal thread (111), so as to detachably assemble the support (10) and the collar (32). The material of the body (31) is polymethyl methacrylate, so as to provide a reliable light path structure, and the collar (32) is titanium metal. The body (31) and the collar (32) are integrally formed, such that the collar (32) is sleeved on the body (31) so as to form a lens column (30), and the outer peripheral wall of the body (31) is provided with a limiting slot (31D) for limiting the collar (32). The support (10) is titanium metal, such that the internal thread (111) and the external thread (321) are metal threads of the same material, and the heat shrinkage ratios of structures of the same material undergoing a temperature change are the same, so that a joint has a high assembly reliability and does not separate or fall off unless an external force is applied thereto. The service life of the artificial cornea is increased, surgical risks are reduced, a patient is protected from secondary injury or being blinded again, and use satisfaction is increased.

Based on 3D printing technology and corneal topography assisted personalized ocular prosthesis manufacturing method, through the high polymer impression material to make the patient's eye side conjunctival sac impression, and obtain the three-dimensional data of the conjunctival sac impression of the affected eye, and establish a three-dimensional model, remove the front surface of the three-dimensional model with the pupil center as the center, and the corneal diameter data of the healthy eye as the diameter of the circular area, and integrate the pupil diameter and corneal anterior surface curvature data of the healthy eye in this area, and finally obtain the three-dimensional model of the ocular prosthesis, and the ocular prosthesis is made through 3D printing technology, because the data of the pupil diameter and corneal anterior surface curvature of the healthy eye are integrated on the front surface of the three-dimensional model of the affected eye, the ocular prosthesis is more realistic and more suitable for the affected eye.

The invention relates to a device for the transplantation of a Descemet's membrane-endothelium graft (5), comprising a longitudinal tube (1), the tube (1) having an inner cavity (2), an inlet opening (3) at its proximal end (PE) through which it is possible to introduce the graft (5) into the cavity (2), and an outlet opening (4) at its distal end (DE) through which it is possible to eject the graft (5) from the cavity (2), particularly into the anterior eye chamber of a patient, a guiding element (6) situated in the cavity (2) of the tube (1) extending from the proximal end area of the tube (1) or device towards the distal end area of the tube (1) or device and having an increasing cross section at least along a part of its extension, particularly by increasing the width of the guiding element (6) more than the height of the guiding element (6), wherein the guiding element (6) extending beyond the outlet opening (4) of the tube into the exterior environment of the tube (1), and having the distal end (6b) of the guiding element (6) being positioned outside of the tube (1) in front of the outlet opening (4) of the tube (1).

The present invention provides a scleral lens with a fenestration and pockets. One fenestration or a plurality of annularly-distributed fenestrations are provided in an optic zone of the scleral lens; and two or more pockets are provided in a pocket annular zone on a posterior surface of the optic zone. The pockets are configured to trap gas bubbles near the fenestration, where the fenestration is located radially outward from the pocket annular zone and not located in a transition zone of the scleral lens, and the transition zone is configured to be located above the limbus of the eyeball during wearing of the scleral lens. The lens of the present invention will not be adsorbed to the cornea, and can be worn comfortably and maintain clear visual acuity for up to 12 hours.

The present invention relates to a dental / medical device consisting of an absorbable synthetic membrane, preferably white to gray in color, comprising poly(dioxanone) and optionally graphene and stem cells, to be used in guided tissue reconstruction and / or regeneration of bone defects and other connective tissues (gum, skin, cartilage or cornea, for example). Furthermore, the present invention relates to the use of said device for the above-related applications and to the process of preparing said device.

Device for storing and transporting a graft (4) or implant, comprising a container (2) that can be filled with a medium (1), preferably a nutrient medium, and a receiving device (3) for the graft (4) or implant that can be arranged in the container (2), wherein the receiving device (3) has a receiving chamber (5) for the graft (4) or implant and two passages (6, 7) leading to the receiving chamber (5), at least one of which (6, 7) is dimensioned for inserting and / or removing the graft (4) or implant into or from the receiving chamber (5), and each of which has a closure device (8, 9) for the two passages (6, 7), at least one of which (8, 9) is permeable to the medium (1), characterized in that at least one of the two closure devices (8, 9) has a grid to provide permeability to the medium (1).

The present application relates to a kind of conjunctival transplantation device for pterygium excision surgery, including first holding unit, second holding unit, support unit, first angle adjusting unit, second angle adjusting unit, first pressing unit, first cutting unit and second cutting unit.Its advantages are that the angle of first cutting unit and second cutting unit is adjusted in proximal end using first holding unit and second holding unit;first angle adjusting unit and second angle adjusting unit are rotated using first pressing unit, and then first cutting unit and second cutting unit cut conjunctival flap on support unit, which integrates multiple dispersed steps into one medical instrument to complete continuously, reducing instrument replacement;the size of conjunctival flap is measured by support unit without damaging the flap, which not only ensures the accuracy of the size and shape of the flap, avoids the error of manual operation, improves the accuracy and efficiency of surgery, but also avoids tissue damage caused by traditional forceps directly holding.

Spacer device 800 for implantation into an eye, comprising a flexible body configured to conform to an anatomical tissue surface of the eye, the body comprising an inner surface 825 and an outer surface 845, wherein the spacer device is configured to reversibly transition between a compressed configuration suitable for feeding through an application element 400 and an expanded configuration defining a convex, internal three-dimensional volume 370 for receiving fluid from an anterior chamber of the eye, wherein the spacer device comprises engagement elements 810, 830, each positioned along and extending along a longitudinal axis of the inner surface 825, and wherein the engagement elements are configured to: (i) engage with an application element 400 to stabilize the spacer device during implantation into the eye, and (ii) engage with the tissue surface after insertion, and wherein a central slot 865 arranged between the engagement elements 810, 830 forms a primary drainage path for the fluid circulation.

The present disclosure provides a solution for maintaining, by monitoring and guidance operations, a desired condition state in an eye of the subject, following an ophthalmological procedure. For example, the procedure may be corneal transplant, either a complete transplant of a corneal or a partial transplant of some layers of the cornea. Following the procedure, a gas bubble is injected into the eye to maintain the corneal graft in position. As long as the gas bubble is located below the corneal graft, it assists in maintaining the graft in position. As the gas bubble is lighter than the medium in the eye, it keeps pushing upwards and applying forces on the graft and preventing it from dislocating. The present disclosure provides a solution that keeps monitoring the gas bubble, or any other condition state resulted by an ophthalmological procedure and providing instructions to the subject in case the gas bubble deviates from certain allowed boundaries within the eye.

A glaucoma drainage device is provided having an elongate body that drains aqueous humor from the anterior chamber of the eye. At least one anchor or wire is configured to extend radially outward beyond the body for fixing the body in the eye. The device including the anchor or wire can be housed within the distal end of a needle inserter and deployed therefrom to implant the device into the eye. The deployment can be carried out either ab externo or ab interno. When the device is loaded inside the needle inserter, the wire or anchor (or part thereof) is retained in a compressed state. When deployed from the needle inserter into the eye, the wire or anchor (or part thereof) is configured to automatically self-expand relative to the compressed state and fixate the device in the eye. Related systems and methods of treating glaucoma are also described and claimed.