40 results about "Aqueous humour" patented technology

Described herein is a device for glaucoma treatment and monitoring that comprises a combination of an intraocular pressure (IOP) sensor and a glaucoma drainage device. The device comprises an IOP sensor and an inductive antenna mounted within a porous biocompatible material that forms the drainage path. The IOP sensor is mounted in a footplate portion of the device and is mountable in the anterior chamber of an eye. The footplate portion is connected to a body portion that houses the spiral antenna by a neck portion which retains the footplate portion in a suitable position within the anterior chamber. Due to its size, the footplate portion housing the IOP sensor can readily be inserted into the anterior chamber with the body portion housing the spiral antenna located outside of the anterior chamber in a sub-scleral space to disperse the aqueous humour.

An apparatus for reducing intraocular pressure is provided. A tube extends from an inlet end in fluid communication with an anterior chamber of the eye, to direct an aqueous humor flow from the anterior chamber to an outlet end in fluid communication with a cavity, defined by a housing, for receiving the aqueous humor. A proximal end of an elongate tubular member defining a longitudinally-extending channel is engaged with the housing such that the channel is in fluid communication with the cavity and such that a distal end of the tubular member is spaced apart from the housing, wherein the channel is configured to receive the aqueous humor from the cavity and to direct the aqueous humor through the distal end to a drainage site disposed distally to the anterior chamber and to the housing. An associated method is also provided.

The invention relates to a stainless steel device for permanent insertion into the sclerocorneal limbus, with different drainage and anchorage systems, enabling the aqueous humour to discharge through one or more virtual spaces from the anterior chamber to an intrascleral space in cases of simple glaucoma or to the equatorial episclera in cases of complex glaucoma, such as neovascular glaucoma. The space is virtual, not real, as in the case of the tubular device. It enables the aqueous humour to discharge slowly and continuously, minimizing the possibility of the chamber being flat or of germs penetrating through the device. Furthermore, the anchorage system is less aggressive, thus reducing the possibility of bleeding.

A drain valve (10) implantable surgically in the eye (O) of a patient for the treatment of glaucoma, comprising a main body (11), and a drainage tube (12), connected at one end with the main body (11) and provided to be implanted in the eye (O) so as to penetrate with its distal tip inside the anterior chamber (CA) of the eye globe (GO), so as to allow the drainage outwards of the aqueous humour (UA), wherein the valve (10) is characterized by a series of significant improvements, including:1) an extractable configuration (12a, 12b) of the drainage tube (12), to allow the adaptation (f1) of the length of the drainage tube (12) during the surgical operation to implant the valve (10);2) a flattened or flat shape in section (12′) of the drainage tube (12, 12a, 12b) suitable for reducing the dimensions in the radial direction (IR) of the drainage tube (12) with respect to the surface of the eye globe (GO);3) a connection free from encumbrances between the tip portion (12f) of the drainage tube (12), provided to penetrate inside the eye globe (GO, CA), and the remaining part (12b′) of the drainage tube (12);4) a series of retaining bags or compartments (11b), formed along the lower or soffit surface (S″) of the main body (11) in contact with the surface of the eye globe (GO), wherein these retaining bags (11b) are associated with respective through holes (11a) extended through the same main body (11) of the valve and are suitable for receiving and retaining the aqueous humour (UA), so as to improve lubrication of the eyeball in the zone of the valve, once implanted;5) a divergent fan-shaped opening (11c) formed on the extrados (S′), not in contact with the eye globe, of the main body (11) of the valve, in order to convey the aqueous humour (UA) and improve the lubrication around the drain valve (10), once implanted; and6. a modified configuration, with respect to conventional drain valves, such as to allow, during the surgical operation, an arrangement, closer to the iris, of the holes (11d) for the insertion of the yarn for fixing the valve to the surface of the eye globe.Thanks to these improvements the drain valve (10) ensures considerably improved and superior performances with respect to the currently known drain valves in use in the medical field for treating glaucoma.

The present invention discloses a disposable negative-pressure anterior chamber Paracentesis syringe which belongs to the technical field of medical supplies. It comprises nine parts, including a needle cap, a Paracentesis syringe, a needle base, an internal needle, a protective cover of the internal needle, an airlock, a needle tube, a collection tube and a collection tube rack. The invention has the advantages that it fixes the Paracentesis syringe during puncture and limits the depth of the needle insertion, releases the aqueous humor slowly to prevent a sudden drop of the intraocular pressure, reduces the risk of the intraocular infection by separating the anterior chamber from outside and the collection tube can collect and store the aqueous humor directly.

The invention discloses a molecular marker lncRNAs NR_026887 for glaucoma diagnosis, a kit and application. The inventor finds that relative to the control group, expression of lncRNAs:NR_026887 in aqueous humour of glaucoma patients is up-regulated., thus hinting that NR_026887 is high expression lncRNAs (long noncoding RNA) of glaucoma and is a biomarker conducive to glaucoma diagnosis. The molecular marker provided by the invention provides a powerful molecular biological basis for diagnosis of glaucoma, and has far-reaching clinical significance and generalization performance.

Provided is an anterior segment aqueous fluid circulating flow simulation device. The organization of the simulation device comprises a cornea (1), a sclera (6), a crystalline lens (12), a vitreous chamber (14), an iris (11) and the like. A functional mechanism comprises a aqueous fluid circulating flow control system, a crystalline lens moving control system, a pupil retardation simulation system and an intraocular temperature adjusting system which work in a cooperative mode, so that normal and abnormal aqueous fluid circulating flow simulation is guaranteed. An auxiliary device comprises an aqueous fluid discharging groove (2), an aqueous fluid flow-in groove (5), a control panel (9), a crystalline lens inner cavity (13), pipelines (3, 4, 23 and 24), a water-leakage-preventing rubber mat (17), an external temperature control system and the like.

The invention discloses an aqueous humor collection device, comprising: an outer cylinder body including a puncture needle installation end and a liquid collection tube installation end; a puncture needle fixedly installed on the puncture needle installation end and including the puncture needle inner end and the puncture needle outer end The liquid collection tube assembly includes a liquid collection tube and a pipe plug for sealing the mouth of the liquid collection tube; wherein, the outer peripheral wall of the liquid collection tube assembly is provided with an annular groove and an annular limiter set by the hoop annular groove, The radially outer end of the annular stopper abuts against the inner peripheral wall of the outer cylinder, the radially outer edge of the pipe plug forms a smooth contact with the inner peripheral wall of the outer cylinder and is provided with a pipe plug arranged along the extending direction of the outer cylinder cavity Exhaust channel, the barrel cavity of the outer cylinder is connected to the tube plug exhaust channel in the cavity area between the tube plug and the installation end of the puncture needle. By adopting the aqueous humor collection device of the present invention, the safety and reliability during anterior chamber puncture can be improved, and the accuracy of subsequent aqueous humor detection can be improved.

A glaucoma aqueous humor drainage device and a glaucoma aqueous humor drainage method, the switch of the valve is controlled by the change of the cavity pressure in the pressure valve, when the intraocular pressure exceeds 12mmHg, the valve is opened, and the valve is connected with drainage The tube drains the aqueous humor to the ocular surface, and relieves the patient's discomfort and dry eyes. It can effectively drain the aqueous humor and avoid scarring caused by the conjunctival flap embedding device and the generation of filtering blebs that lead to increased intraocular pressure and cause surgical failure. .