52 results about "Cataract patient" patented technology

An adaptive optic for refractive lens exchange or cataract patients. The intracapsular implant comprises an elastomeric monolith with an equilibrium memory shape that imparts to the capsular sac's periphery the natural shape of the capsule in an accommodated state. In one embodiment, the monolith carries a recessed deformable central lens portion having an ultralow modulus that allows for high accommodative amplitude in response to equatorial tensioning. In a preferred embodiment, the adaptive optic defines an anisotropic modulus with a plurality of on-axis, rotationally symmetric elastomer block portions each having a different Young's modulus. The invention further provides composite materials for enhancing deformation of lens curvature, including the use of auxetic polymeric materials and negative stiffness materials. In preferred embodiments, at least a portion of the lens is fabricated of a shape memory polymer that provides a memory shape and a temporary shape with a reduced cross-sectional shape for introduction into the patient's eye.

An intraocular lens is provided that having optical parameters that may be adjusted in-situ, and is particularly useful in cataract patients that require an adjustment in the optical power of the lens post-implantation. The lens body carries an array of interior fluid-filled cells in which fluid is controllably moved by micropumps upon application of energy from an external source to move a fluid media into the cells to thereby alter the lens surface shape.

An intraocular lens (IOL) that provides for optical power adjustment following its implantation, for example, for use in treating cataract patients. The lens body has first and second surface portions that bound at least one interior chamber or space that extends from the central optic portion to the lens periphery. The interior chamber or space has a microporous body that is intermediate inner and outer portions of the space. In one embodiment, the microporous body is capable of cooperating with an external Rf or light source to expose a charge to a charge-carrying fluid within the interior chamber. By this system, fluid flows are induced to alter the optical parameters of the lens.

A lens is provided that having optical parameters that may be adjusted in-situ, and is particularly useful as an IOL for use in cataract patients that require an adjustment in the optical power of the lens post-implantation. In one embodiment, the lens body carries an array of interior fluid-filled cells in which fluid is controllably moved upon application of energy from an external source to move a fluid media into or out of the cells to thereby alter the lens surface shape.

The invention relates to an intraocular lens and can provide a new way to prevent after-cataract and improve the quality of life of cataract patients. A method for preparing an intraocular lens for preventing after-cataract based on photothermal conversion comprises the following steps: (1) using a circular protective film sheet pre-trimmed into an appropriate size to cover the surface of the central optical zone of the intraocular lens; (2) preparing a dopamine buffer solution, wherein the concentration of dopamine in the dopamine buffer solution is 2-6 mg / mL, the concentration of an oxidantand a reducing agent is 5-20 mmol / L, and the balance is a buffer; (3) placing the intraocular lens in the above dopamine buffer solution for 10-50 minutes; (4) taking the intraocular lens out, removing the protective film sheet and rinsing the lens with ultrapure water for 3-5 times; (5) drying the rinsed intraocular lens with nitrogen and storing the intraocular lens in the dark.

The invention belongs to the technical field of a medical intraocular lens, and particularly relates to a self-cleaning intraocular lens and a preparation method thereof. The preparation method comprises the specific steps of: (1) flushing the surface of an intraocular lens material with sterile double-distilled water, and blow-drying the surface of the intraocular lens material with nitrogen flow; (2) carrying out modification on the surface of the intraocular lens material by utilizing a plasma beam, and filling in O2 to form an oxygen ion beam to impact the surface of the intraocular lens to generate free radicals, so that a certain convex micro-nano structure is formed on the surface of the intraocular lens; (3) grafting the surface of the intraocular lens material, which is subjectedto plasma beam processing, with a PDMS (Polydimethylsiloxane) molecular chain by utilizing a chemical vapor deposition method; and (4) carrying out ethylene oxide sterilization packaging on the grafted self-cleaning intraocular lens. According to the preparation method of the intraocular lens, a coating based on self-cleaning ''similar liquid'' is formed on the surface; and according to the method, optical transparency of the intraocular lens can be kept for the post-cataract surgery, related complications such as posterior capsular opacity and the like can be prevented and treated, and guarantee can be provided for health of cataract patients.

The invention provides an artificial iris capable of fixing an artificial lens as well as a material and a processing method of the artificial iris. The artificial iris comprises an artificial iris diaphragm, a loop for fixing the artificial iris, and a fixing structure for fixing the artificial lens. By utilizing the self convex structure of the artificial iris, the artificial iris can penetrate through the sclera wall and be flexibly fixed to the sclera wall, so that the operation of fixing the suture is avoided, the operation is simple and feasible, the iris is kept stable in the eye, meanwhile, a suture used for fixing is not needed during implantation, the viscoelasticity enables the iris to easily pass through the small incision, and no injury is caused. The artificial iris provided by the invention is further provided with the fixing structure for fixing the artificial lens, so that the artificial lens can be conveniently fixed to the iris as for the cataract patient with the injured sac.

The invention relates to application of circulating miRNA in serving as age-related macular degeneration diagnostic markers. Expression differences of miRNA between patients with neovascular AMD and patients with cataract are detected through a miRNA expression chip, ten pieces of miRNA are selected from all miRNA subjected to differential expression for verification, a sample is enlarged, special miRNA expression is conducted through a fluorescent quantitative PCR method, comparison is conducted on the content of different miRNA in the patients with AMD and a control group, and the feasibility of serving as the diagnostic markers is verified. It is displayed through ROC curve analysis that AUC of miR-27a-3p, AUC of miR-29b-3p and AUC of miR-195-5p are 79.1%, 72.7% and 70.7% respectively. It is shown that miR-27a-3p, miR-29b-3p and miR-195-5p can serve as the age-related macular degeneration diagnostic markers.

The invention discloses a novel capsulorhexis needle special for ophthalmic cataract surgery, The novel capsulorhexis needle comprises an electronic capsulorhexis needle body, and a positive and negative rotation control device and a speed setting device are arranged on the electronic capsulorhexis needle body. According to the novel capsulorhexis needle special for the ophthalmologic cataract surgery, all operations of the ophthalmic cataract surgery are completed, the capsulorhexis needle is controlled by an operating arm, instability of hand operation of a doctor is effectively avoided, andthe precision of the capsulorhexis needle meets the requirement for fine operation. Meanwhile, in consideration of cataract patients suffering from hypertension, a blood pressure monitoring device isarranged, blood pressure monitoring is conducted on the patients in the operation process, and it is guaranteed that the operation is conducted smoothly. The novel capsulorhexis needle has the characteristics of high fineness and multiple functions, and is suitable for popularization and application.

Relating to the field of traditional Chinese medicines, the invention discloses a traditional Chinese medicine treating early cataract and its preparation method. The traditional Chinese medicine is prepared by decocting the following raw materials by mass: 5-10 of fructus lycii, 6-8 of rehmannia glutinosa, 1-3 of Chrysanthemum, 2-4 of Rhizoma Anemarrhenae, 2-5 of phellodendron, 3-5 of Salvia Miltiorrhiza, 4-8 of Eucommia, 2-4 of rhizoma alismatis, 1-2 of Angelica, 5-8 of Poria cocos, 2-3 of white paeony roots, 5-7 of Caulis Dendrobii, 3-5 of Polygonatum odoratum, 2-3 of Ligustrum lucidum, 3-5 of Cornus officinalis, 4-5 of parasitic loranthus, and 2-3 of American ginseng. The materials are added into pillis ophidiae stir-fried to yellow, mung beans and white sugar, and then the mixture is steamed on high heat for 25-35min, thus obtaining the product. The invention has significant efficacy, provides an effective treatment scheme for cataract patients, and makes patients exempted from operation suffering.

The invention relates to an operation intelligent decision-making system suitable for high myopia cataract and an establishment method thereof. The establishment method comprises the following steps:constructing a deep learning model being composed of an evaluation network and a decision network, configuring evaluation network to comprise a LOCSIII grading deep learning model, an Elasticity kernel hardness grading deep learning model and a fundus judgment model, and configuring the decision network to combine the cataract degree and fundus grading with patient basic information, eyesight, intraocular pressure, an A-ultrasonic / IOLmaster report, corneal endothelium counting, corneal astigmatism, a B-ultrasonic report and other information, map the information to a high-dimensional space through a kernel function, and then establish a linear regression model; constructing a training set; and carrying out training learning and parameter adjustment on the model by using a training set. Thesystem comprises a storage device, an evaluation module, a decision module and a test evaluation adjustment module. The method can quickly and accurately identify the cataract degree and fundus conditions of a high myopia cataract patient, provide comprehensive operation decisions for doctors, and improve the prevention and treatment homogeneity.

The invention relates to an intraocular lens diopter calculation system based on machine learning. The intraocular lens diopter calculation system comprises a prediction model, an input module, a calculation module, an additional module and an output module. The calculation module is used for acquiring a diopter number of an intraocular lens to be implanted (IOL) by taking target equivalent spherical power as an ideal value and taking preoperative information of a cataract patient as input on the basis of a prediction model; the additional module is used for providing a plurality of differentsimulated intraocular lens diopters to the calculation module, and the calculation module generates postoperative optometry equivalent spherical lenses corresponding to the different simulated intraocular lens diopters. The artificial intelligence active learning data characteristics are fully utilized, the error calculation capacity is autonomously optimized, the diopter of the intraocular lens needing to be implanted in cataract surgery is accurately calculated, eyeball biological parameters of all dimensions are matched, and the eyeball prediction accuracy of the extreme eyeball biologicalparameters is higher.

The invention provides a femtosecond laser cataract emulsifying treatment system which comprises an emulsifier, wherein a needle which can touch the lenticular nucleus of a cataract patient is arranged at the front end of the emulsifier; two channels which can be led to the outside of the emulsifier are arranged in the emulsifier: a negative pressure channel and a lavage suction channel; the end of the negative pressure channel led to the outside of the emulsifier is connected with a negative pressure unit capable of generating a pressure for adsorbing the lenticular nucleus; the end of the lavage suction channel led to the outside of the emulsifier is connected with a lavage suction unit capable of sucking out the emulsified lenticular nucleus; the back end of the emulsifier is connected with a femtosecond laser generator capable of generating femtosecond laser; and the femtosecond laser, the negative pressure unit and the lavage suction unit are all connected with a computer control unit. By adopting full-femtosecond laser capsulorhexis, the system imposes relatively low requirements on the experiences of the operation doctor and can realize accurate positioning of capsulorhexis through computer control.

The invention provides a femtosecond laser cataract emulsification instrument which comprises an emulsification instrument body. A needle capable of being in contact with a lenticular nucleus of a cataract patient is arranged at the front end of the emulsification instrument body, and a reflector is arranged at the front end of the needle. Two channels capable of leading to the outside of the emulsification instrument body are arranged in the emulsification instrument body and comprise the negative pressure channel and the filling and suction channel. A splitter is obliquely arranged at the front end in the emulsification instrument body, and a first lens, a rotatable wedge-shaped mirror and a movable second lens are sequentially arranged at the positions, behind the splitter, in the emulsification instrument body. According to the emulsification instrument, full femtosecond lasers are used for tearing bladders, the requirement for the experience of surgeons is low, and the emulsification efficiency is high.

The present invention relates to optical system for eyesight detecting instrument, and is especially the optical system and detection method of instrument for measuring the latent eyesight of retina in eye of different visual degree. The instrument is specially for detecting the visual function of eyes of cataract sufferer, and the design and relevant parameters of different optical parts are given out. Transmission eyesight resolution chart is adopted for enough fine imaging light beam entering the pupil and enough light flux. The miniature interval in the cloudy lens of the cataract sufferer is imaged onto the retina and the transmission eyesight resolution chart is moved to focus, so as to measure the diopter of the eye. The eyesight is detected via watching the eyesight resolution chart. The instrument of the present invention is significant in cataract treatment.

The invention discloses a control system and method for a cataract patient in a medical consortium. The control system comprises a cataract management cloud platform, a patient server, an expert server and a primary hospital server, wherein the cataract management cloud platform is connected with the patient server, the expert server and the primary hospital server to realize data interaction, thecataract management cloud platform comprises a doctor-patient management service engine, a screening module, an HIS docking module and a database, the primary hospital server comprises an eyeground examination management module and a digital slit lamp device used for shooting eyeground imaging pictures of a patient, the expert server comprises an expert diagnosis module and an expert diagnosis data management module, and the patient server comprises a login module, an information management module and a consultation module. The management method of a cataract patient in a medical consortium comprises: 1, carrying out primary diagnosis or cataract screening on a patient; 2, carrying out intelligent diagnosis; and 3, intervening by doctors.

The invention discloses an ultrasonic capsulorhexis needle for cataract suction, which comprises a metal connector and a needle body. The metal connector and the needle body are of a split structure; the needle body is connected to the rear of the metal connector; the metal connector is fixedly connected to the far end of an ultrasonic emulsification handle; and the furthest end of the needle body is the tip end. The ultrasonic capsulorhexis needle has the beneficial effects that weaknesses of burning a capsule by an electrode are avoided; by the tip end of the capsulorhexis needle which is driven ultrasonically, a lens capsule bag can be more effectively and softly torn; and moreover, the ultrasonic frequency can be flexibly reduced and even not started according to conditions and only the conventional step of manually tearing the capsule is adopted, so that great flexibility is brought to a doctor. According to the ultrasonic capsulorhexis needle for cataract suction, the pressure applied to eyes in the process of tearing the capsule can be reduced, the capsulorhexis process is easier to operate, safety is improved, and the ultrasonic capsulorhexis needle is particularly further required by patients suffering from special conditions, such as cataract patients of which ciliary suspensory ligaments are weak, extra-hard or excessively soft.

The Chinese medicine pill is prepared with Chinese yam, dogwood, Rhizoma Alismatis, tuchahoe, tree peony bark and other four Chinese medicinal materials as well as honey or chrysanthemum molasses. It may be used for treating cataract effectively.

A medical gel for preventing and treating cataract contains the hydrolytic liquid of pearl powder, borneol, Zn, beta-carotene, VE, gel matrix and pharmacologically acceptable carrier. Its preparing process is also disclosed.

The embodiment of the invention discloses a method and a device for denoising a fundus color photo image of a cataract patient, equipment and a medium. The method comprises the following steps: acquiring a clear eye fundus image of a normal person and a real noise eye fundus image of the cataract patient; adding noise to the clear fundus image to obtain a simulated noise fundus image; constructing a generator and denoising the simulated noise eye fundus image by using the generator to obtain a simulated denoised image; constructing a first discriminator, respectively inputting the combination of the simulated noise fundus image, the clear fundus image and the simulated de-noised image to obtain the loss of the first discriminator, and optimizing the generator according to the loss; denoising the real noise eye fundus image by using the optimized generator to obtain a real denoised image; constructing a second discriminator, inputting the real denoised image and the simulated denoised image to obtain the loss of the second discriminator, and optimizing the generator according to the loss; and denoising the real noise eye fundus image according to the re-optimized generator to obtain a final denoising result. Effective denoising of the eye fundus image of the cataract patient is realized.

The invention discloses an aspherical artificial lens capable of completely correcting mesopic vision. The surface shape of the front surface of an optical part of the aspherical artificial lens or the surface shape of the rear surface of the optical part is aspherical. A corneal spherical aberration range corrected by the aspherical artificial lens is -0.1 to -0.2 micron. Compared with an aspherical artificial lens sold in the market at present, the aspherical artificial lens capable of completely correcting mesopic vision is capable of completely correcting the common corneal spherical aberration of the mesopic vision; the influence of eccentricity and inclination of implantation of the artificial lens on the vision quality can be reduced, so that corresponding patients with cataract can obtain higher vision quality.

The invention provides a cataract patient visual impairment degree evaluation system based on an AI technology. The cataract patient visual impairment degree evaluation system comprises an information acquisition module, a fundus image acquisition module, an image identification module, an image classification module, a disease condition evaluation module and a diagnosis and treatment suggestion module. Whether a patient suffers from cataract or not is automatically screened according to the fuzzy degree information in the mydriasis-free fundus image, and then the visual impairment degree of the fundus image marked with cataract is interpreted and graded, so that diagnosis and treatment suggestions are given in a targeted mode for patients with different degrees of visual impairment caused by cataract. According to the method, the relation between the severity of the cataract and the degree of visual impairment can be visually reflected, the accuracy of the evaluation result can be improved, and meanwhile, the process of screening the cataract through fundus photography has the advantages of being simple and rapid.

Based on the identification by colorimetry of a colour image of the fundus of the eye of an individual, obtained by specialised cameras (fundus camera or retinograph). The method and the device of the present invention enable establishing a direct relation between the chromatic properties of the various tissues of the optic nerve (10) and the amount of haemoglobin (Hb) in the optic nerve head (10), allowing identification and clearly distinguishing the irrigated regions of the optic nerve (10) from the non-irrigated regions or those with atrophy, constituting a tool of great interest in monitoring and diagnosis of glaucomatous disease and other optic diseases affecting vascularisation. This method also allows taking into account the effect of loss of transparency of the lens in patients with cataracts, as this effect is compensated without affecting the final results of the determination of the amount of haemoglobin (Hb).

The invention provides an anti-cataract euphadienol preparation for eyes as well as a preparation method and the application thereof. The anti-cataract euphadienol preparation contains euphadienol existing in an independent form or a combined form, and further contains a surfactant and a cosolvent having a medicinal eye adjuvant. The size of a nano particle of the euphadienol is 20 to 100 nm. Thepreparation for eyes has an extremely good treating effect on cataract, can be used for treating the cataract in different periods, is particularly applicable to patients suffering from primary senilecataract, mild diabetic cataract or concurrent cataract, and can improve the physiological functions of a human body, accelerate the blood circulation and nutrition metabolism of anterior segments, improve the permeability of a phacocyst, recover the physiological barrier effect, effectively control the turbidity of a crystalline lens and promote turbidity absorption.

The invention discloses a traditional Chinese medicine composition for treating cataract and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine composition disclosed by the invention can be used for effectively curing cataract and preventing recurrence after cure. The traditional Chinese medicine composition is composed of the following traditional Chinese medicine raw materials in parts by weight: 8-12 parts of folium mori, 3-8 parts of horsetail, 5-10 parts of feather cockscomb seed, 8-12 parts of asparagus fern, 2-9 parts of tortoise shell, 5-10 parts of mulberry fruit, 3-8 parts of amber, 1-5 parts of sculellaria barbata, 1-3 parts of elecampane, 1-5 parts of polygonum multiflorum, 3-8 parts of eucommia ulmoides and 2-7 parts of pipewort. The traditional Chinese medicine composition disclosed by the invention is suitable for a variety of cataract patients for taking, the cure rate is 99% and the efficiency is 100%.