A device and a method for ultrafast picosecond pulse laser machining of a super-hydrophobicity micro-structure surface belong to the field of preparation of functional micro-structure surfaces, and aim to solve the problems of high investment and low output of an existing machining process and existing machining technology for functional elements. The device comprises an ultrafast picosecond pulse laser source, an optical isolator, five reflectors, a rotary liquid crystal polarizing film, a polarization beam splitter, two beam collectors, a half wave plate, a focusing lens, frequency-doubling generator LBO (lithium triborate) crystal, a dichroic mirror, a light control device, a beam profile curvometer, a beam amplifying component Kepler beam expander, a focusing machining lens, a machining platform, a microscopy imaging CCD (charge coupled device) component and a control system. The method includes the stepsof: fixing a steel workpiece onto a surface driven by a Z-directional guide rail of the machining platform; adjusting a light path; detecting the surface of the workpiece by a probe; and driving the workpiece to move by means of movement of an X-directional guide rail and a Y-directional guide rail of the machining platform. The device and the method are used for preparing the super-hydrophobicity micro-structure surface.