Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

92 results about "Ultrasonic emulsification" patented technology

Core-shell nano-enzyme composite spray gel dressing as well as preparation method and application thereof

The invention discloses a core-shell nano-enzyme composite spray gel dressing and a preparation method and application thereof.The dressing comprises a component A prepared from sodium alginate, N-isopropylacrylamide PNIPAM, core-shell nano-enzyme and curcumin and a component B of a divalent metal salt solution, and the component A and the component B are sprayed at the same time to form the core-shell nano-enzyme composite spray gel dressing. The preparation method of the core-shell nano enzyme comprises the following steps: mixing potassium ferrocyanide, ferric trichloride and polyvinylpyrrolidone to obtain a Prussian blue nano particle precursor solution; carrying out ultrasonic emulsification treatment and replacement on the curcumin core solution and the Prussian blue nanoparticle precursor solution; and freeze-drying to obtain the core-shell nano-enzyme. Through rapid ionic crosslinking of sodium alginate and divalent metal ions and the temperature-sensitive phase change characteristic of the temperature-sensitive polymer poly (N-isopropylacrylamide), the gel dressing is rapidly formed, the damaged skin is effectively covered and protected, the excellent antioxidant, anti-inflammatory and antibacterial capabilities are achieved, and the healing cycle of the radiodermatitis wound can be remarkably shortened.
Owner:THE PEOPLES HOSPITAL SHAANXI PROV

Layered volatilization sleep-aiding essential oil product based on lavender essential oil and sandalwood essential oil and preparation method thereof

The invention discloses a layered volatilization sleep-aiding essential oil product based on lavender essential oil and sandalwood essential oil and a preparation method of the layered volatilization sleep-aiding essential oil product. The preparation method comprises the following steps: mixing a high-volatility essential oil component and a low-volatility essential oil component with a natural emulsifier according to a specific ratio, carrying out an ultrasonic emulsification technology to obtain a nano-emulsion, and drying the nano-emulsion to prepare the microcapsule essential oil particles. According to the invention, different volatile components are coated by a specific emulsification method to reduce the volatilization loss and improve the stability, and layered slow release with synchronous starting and controllable speed is realized by utilizing the difference between high and low volatility; wherein the high-volatility component is quickly released in the early stage to provide an instant tranquilizing and allaying excitement effect, and the low-volatility component is slowly released in the later stage to provide a continuous sleep aiding effect. The layered volatile sleep-aiding essential oil product based on the lavender essential oil and the sandalwood essential oil provided by the invention is good in stability, has the advantages of rapid effect taking, lasting controlled release, uniform volatilization, good skin compatibility and the like, and can be used for preparing more sleep-aiding and nerve-soothing products.
Owner:GUANGDONG UNIV OF TECH

Preparation method of high-temperature-creep-resistant nano-composite pressure vessel steel

The preparation method of the high-temperature-creep-resistant nano-composite pressure vessel steel comprises the following steps that a lead sulfide precursor is dissolved in an organic solvent, and heating reaction is conducted under the inert gas condition to generate lead sulfide quantum dots; mixing quantum dots with amphiphilic molecules, and performing ultrasonic emulsification to form a quantum dot colloidal solution; mixing the quantum dot colloidal solution with supercritical carbon dioxide to form a homogeneous fluid phase; the steel matrix is placed in a high-pressure reaction kettle, the homogeneous fluid phase is introduced, permeation is conducted for 2-4 h under the conditions that the pressure is 10-15 MPa and the temperature is 50-70 DEG C, and a steel billet is obtained; the steel billet is placed in hot isostatic pressing equipment, heat preservation and pressure maintaining are conducted for 1-2 h in the inert gas environment under the conditions that the pressure ranges from 150 MPa to 200 MPa and the temperature ranges from 800 DEG C to 900 DEG C, and then the steel billet is cooled to the room temperature; semiconductor quantum dots are introduced into a metal matrix, atomic-scale interface strengthening is achieved through the quantum effect and the supercritical fluid permeation technology, and the steady-state creep rate of the material at the temperature of 600 DEG C can be reduced to 1 / 10 of that of a traditional process by combining the microcosmic strengthening advantage of the quantum dots and the macroscopic permeation advantage of supercritical fluid.
Owner:JINDING HEAVY IND CO LTD

Efficient flame-retardant fire extinguishing agent for rapidly extinguishing lithium battery fire and preparation formula

The invention discloses an efficient flame-retardant fire extinguishing agent for rapidly extinguishing a lithium battery fire and a preparation formula, and relates to the technical field of fire fighting. The fire extinguishing agent is composed of a liquid-phase component and a solid-phase component, wherein the liquid-phase component comprises ethylene glycol, triethanolamine, fluoroalkyl betaine, sodium dodecyl benzene sulfonate, a phosphate flame retardant, an orange peel extracting solution and purified water; the solid-phase component comprises dodecyl sulfate, ammonium phosphate, potassium perchlorate, sodium carboxymethyl cellulose, polyacrylamide, benzotriazole and the like. The method comprises the following steps: drying and activating solid-phase components after graded crushing, and stirring in a nitrogen atmosphere; carrying out segmented treatment on liquid-phase components, and carrying out ultrasonic emulsification on an orange peel extracting solution; and after solid-liquid mixing, carrying out vacuum defoaming, high-speed shearing dispersion and homogenization treatment. According to the lithium battery fire extinguishing agent, component particle sizes with different dissolution rates are matched through graded crushing, nanoscale dispersion is achieved through ultrasonic emulsification, the bubble residual rate is reduced through vacuum defoaming, and the problems that a traditional lithium battery fire extinguishing agent is low in insulativity, low in cooling efficiency and insufficient in flame retardant efficiency are solved.
Owner:HEBEI JICHUAN IND CORP +1

Phacoemulsification irrigation assembly

The application discloses an ultrasonic emulsification perfusion assembly, which comprises a metal connector, a plastic needle tube arranged in the metal connector, a metal perfusion sleeve provided with a water inlet and a perfusion port, and a plastic clamping perfusion sleeve which is sleeved outside the metal perfusion sleeve and forms a liquid storage space, wherein the water inlet is arranged in the liquid storage space. The application has the following beneficial effects: the slender needle head of the plastic needle tube can improve the stability of the anterior chamber and reduce the probability of surge occurrence; the relatively soft plastic needle head tip can also reduce the probability of puncturing the lens capsule; the metal perfusion sleeve effectively separates the ultrasonic emulsification needle tube body from the extrusion of the incision, greatly reduces or even eliminates the incision burn caused by ultrasonic friction; the relatively hard metal perfusion sleeve effectively prevents the perfusion liquid from being reduced or blocked due to the extrusion or distortion of the incision, thereby improving the stability of the anterior chamber and reducing the probability of surge occurrence.
Owner:INNOLCON MEDICAL TECHNOLOGY (SUZHOU) CO LTD

Preparation method and application of resveratrol-polylactic acid microspheres

The application provides a preparation method and application of resveratrol-polylactic acid microspheres, and relates to the technical field of biological agents, quantitative resveratrol is dissolved in methanol as O1 phase; quantitative polylactic acid is dissolved in an oil phase solution (ethyl acetate, dichloromethane, trichloromethane) as O2 phase; ammonium bicarbonate, sodium bicarbonate, sodium chloride and hydrogen peroxide are used as a porogen; O1 phase, O2 phase and the porogen solution are subjected to ultrasonic emulsification to obtain O / O primary emulsion; the O / O primary emulsion is added to a polyvinyl alcohol aqueous solution under stirring to obtain O / O / W multiple emulsion; the obtained O / O / W multiple emulsion is subjected to mechanical stirring to remove the oil phase solution in the O / O / W multiple emulsion, and then is subjected to standing, centrifugation, washing, drying and the like to obtain resveratrol-polylactic acid microspheres with uniform size. The resveratrol-polylactic acid microspheres of the application break through the bottleneck of poor water solubility of resveratrol, can effectively prolong the drug action time, and have good antibacterial effect.
Owner:HUBEI UNIV OF SCI & TECH

Natural bacteriostatic material and preparation method and application thereof

The application relates to the field of food preservation, in particular to a natural bacteriostatic material and a preparation method and application thereof, and a preparation method of the natural bacteriostatic material, which comprises the following steps: mixing natural gelatin and dextran with deionized water, stirring, and freeze-drying to obtain a gelatin-dextran mixture powder, wherein the mass ratio of the natural gelatin to the dextran is 1-2:1-4, and the molecular weight of the dextran is 150-200 kDa; performing a glycosylation reaction on the gelatin-dextran mixture powder to obtain a gelatin-dextran conjugate; dissolving the gelatin-dextran conjugate in a buffer solution to obtain an emulsifier; and homogenizing edible essential oil, the emulsifier and deionized water, and performing ultrasonic emulsification to obtain the natural bacteriostatic material. The preparation method is simple, the conditions are simple, the prepared natural bacteriostatic material has good stability, and the shelf life of food can be prolonged.
Owner:KUNMING UNIV OF SCI & TECH

Preparation method for adiposome

Provided is a preparation method for an adiposome, comprising the following steps: S1) subjecting polar lipids and neutral lipids to intermittent ultrasonic emulsification in a buffer solution to obtain a crude emulsion; and S2) purifying the crude emulsion to obtain the adiposome. Compared with the prior art, the present invention uses an ultrasonic emulsification method to prepare the adiposome, so that the quality of the adiposome prepared in different batches is controllable, and the preparation of the adiposome can be efficiently completed. Moreover, high-energy mechanical vibration and ultrasonic cavitation effects of ultrasonic waves are utilized in the ultrasonic emulsification method to widen the selection of raw materials for adiposomes, so that the method can be used to not only prepare an adiposome with unsaturated fatty acid chain phospholipids and neutral lipids as raw materials, but also synthesize an adiposome with saturated fatty acid chain phospholipids, neutral lipids, or high-melting-point lipids as raw materials. In addition, the utilization of raw materials can be improved, and the scale of adiposome production can be expanded.
Owner:WECARELIFE BIOTECH CO LTD

Pickering emulsion with stable protein-polyphenol coating modified particles as well as preparation method and application of Pickering emulsion

The invention belongs to the technical field of biological medicine, and particularly relates to a Pickering emulsion with stable protein-polyphenol coating modified particles and a preparation method and application thereof.The preparation method comprises the following steps that protein and polyphenol are used for modifying solid particles, and the protein-polyphenol coating modified particles are obtained; dispersing the protein-polyphenol coating modified particles in water to obtain a dispersion liquid of the protein-polyphenol coating modified particles; and mixing the dispersion liquid with an oil phase, and carrying out high-speed homogenization or ultrasonic emulsification to obtain the Pickering emulsion. By adopting the preparation method to effectively modify the solid particles, not only can the inherent properties of the solid particles and the structure and function of protein be maintained, but also the Pickering emulsion prepared from the modified particles is uniform in droplet size and has excellent storage stability, and the service life of the Pickering emulsion is prolonged. The antioxidant and anti-inflammatory characteristics of polyphenol and the catalysis functions of protein are realized.
Owner:SHANDONG UNIV

Systems and methods for surgical handpieces and multi-modal tips

In certain embodiments, a surgical handpiece system includes a phacoemulsification tip, a fluid management system, an ultrasound drive system, and a controller. The phacoemulsification tip is attached to the shaft. The fluid management system is configured to manage inflow and outflow of fluid from an ocular surgical site. The ultrasonic drive system is configured to generate torsional and longitudinal vibrations in the phacoemulsification tip. The controller is configured to analyze a voltage and a current applied to the ultrasonic drive system using fast Fourier transform (FFT), and tune an application frequency of the torsional vibration and the longitudinal vibration according to at least one resonant frequency.
Owner:ALCON INC

Long-acting slow-release antibacterial preservative paper based on Pickering emulsion and preparation method of long-acting slow-release antibacterial preservative paper

The invention discloses long-acting slow-release antibacterial preservative paper based on Pickering emulsion and a preparation method of the long-acting slow-release antibacterial preservative paper. The long-acting slow-release antibacterial preservative paper comprises a paper-based carrier and an antibacterial functional layer, wherein the surface of the paper-based carrier is coated with the antibacterial functional layer; the antibacterial functional layer is formed by mixing a Pickering emulsion and a polyvinyl alcohol / gelatin composite base material to form a film; the Pickering emulsion is prepared by taking Tempo oxidized nanocellulose and ethyl lauroyl arginate hydrochloride water suspension as a water phase and performing ultrasonic emulsification on the water phase and origanum vulgare essential oil according to an oil-water volume ratio of 1: 9; wherein the mixing ratio of the Pickering emulsion to the composite base material is (30 to 50): 50; the mass percent concentration of the Tempo oxidized nanocellulose in the water-phase suspension liquid is 0.2 wt%, and the mass percent concentration of the ethyl lauroyl arginate hydrochloride in the water-phase suspension liquid is 0.01 wt%. Through material innovation and process optimization, the antibacterial property, the slow release property, the environmental protection property and the industrial application are remarkably superior to those of the prior art, and an efficient and reliable solution is provided for green packaging in the fields of food, medicine and the like.
Owner:ZHEJIANG UNIV OF TECH +1

Micro-emulsion collecting agent for flotation of high-mud-content and high-oxidation molybdenite and preparation and application of micro-emulsion collecting agent

The invention discloses a microemulsion collecting agent for flotation of high-mud-content and high-oxidation molybdenite and preparation and application of the microemulsion collecting agent and belongs to the technical field of mineral processing, kerosene, xanthate or black powder collecting agents, a main emulsifier, a cosurfactant and water are mixed according to a certain proportion and then subjected to ultrasonic emulsification treatment, and the microemulsion collecting agent is obtained. According to the micro-emulsion collecting agent prepared through the method, after one-time roughing and two-time scavenging are conducted, the molybdenum recovery rate is remarkably increased compared with the molybdenum recovery rate when a kerosene collecting agent is singly used, the micro-emulsion collecting agent is simple in preparation method, high in emulsion stability, high in dispersity in ore pulp and free of slime interference, and the separation and recovery problem of high-argillization molybdenite is well solved.
Owner:ZHENGZHOU UNIV

Neutrophile granulocyte membrane and stem cell exosome mixed wrapped bionic magnetic nano motor and preparation method and application thereof

The invention discloses a preparation method of a bionic magnetic nano-motor mixed and wrapped by a neutrophile granulocyte membrane and a stem cell exosome. The bionic magnetic nano-motor comprises the neutrophile granulocyte membrane, the stem cell exosome, a polylactic acid-glycolic acid copolymer and an anti-inflammatory drug. According to the method, a layer of polylactic acid-glycolic acid copolymer is wrapped outside magnetic ferroferric oxide nanoparticles and an anti-inflammatory drug by utilizing an ultrasonic emulsification method, and finally the polylactic acid-glycolic acid copolymer is wrapped by utilizing a neutrophile granulocyte membrane and a stem cell exosome, so that the bionic magnetic nano motor is obtained, and the motor has good biocompatibility. Meanwhile, the motor has an immune escape function and can resist phagocytosis of macrophages in blood. And under the control of an external alternating magnetic field, the medicine can accurately reach a spinal cord injury part, and the effects of inflammation inhibition and neuron recovery can be achieved under the mixed action of neutrophile granulocyte membranes, stem cell exosomes and anti-inflammatory drugs.
Owner:HARBIN INST OF TECH

Improved bag tension section

The utility model discloses an improved capsular bag tension section which comprises a main body ring, the whole main body ring is in an arc shape, the span of a main body is 120 degrees, clamping positioning holes are formed in the two ends of the main body ring, the main body ring and the clamping positioning holes are connected in a smooth transition mode, and a sclera fixing hook is arranged on the inner side of the middle of the main body ring. According to the utility model, fixed support can be realized in a small-range area of the capsular bag, permanent support can be realized through sclera suture, a plurality of capsular bag tension sections can be used in the same capsular bag when necessary, and when circumferential support is needed, the capsular bag tension sections can be combined with a capsular bag tension ring for use, so that the use is convenient. According to the utility model, 360-degree expansive force cannot be generated, the device can be used for suspension ligament fracture in a larger range, the stable capsular bag can be used before cataract ultrasonic emulsification, the tension section of the capsular bag can be implanted after a crystalline lens is sucked away, and the device is particularly suitable for children with small capsular bag diameter and incomplete dislocation of crystalline lens or small spherical crystalline lens patients.
Owner:TIANJIN SHI JI KANG TAI BIOMEDICAL ENG CO LTD

Micro-liquid injection system and method thereof

The application provides a micro-liquid injection system and a method thereof, and relates to the technical field of medical devices, and solves the technical problem of inconvenient use of an injection device for subretinal drug injection used in the prior art. The system comprises an injection cylinder, a piston, a connecting hose, a transfusion connector, a needle, and a connecting piece. The piston is arranged in the injection cylinder. The injection cylinder is connected with the needle through the transfusion connector and the connecting hose. The injection cylinder is connected with a vitreous body cutting and ultrasonic emulsification integrated machine (hereinafter referred to as a vitreous body cutting machine) through the connecting piece. The application provides a micro-liquid injection system. By adding the transfusion connector, unidirectional conduction and instantaneous positive pressure can be generated, so that the injection of bubbles can be avoided as much as possible when an ophthalmologist or the like performs drug injection. The connecting hose is arranged between the injection cylinder and the needle, the distance between the injection cylinder and the needle is increased, and a nurse can observe the display on the syringe to remind the doctor of the drug injection amount.
Owner:PEKING UNION MEDICAL COLLEGE HOSPITAL

Fabric containing bacteriostatic microspheres and preparation method thereof

The invention relates to the technical field of textile manufacturing and daily necessities, in particular to a fabric containing bacteriostatic microspheres and a preparation method of the fabric. The preparation method of the fabric comprises the following steps: dissolving the plant extraction type bacteriostatic agent in pure water with the pH value of 8.5-9.5 and the temperature of more than or equal to 80 DEG C to form a bacteriostatic agent solution; polymerizing polylactic acid and polyethylene glycol according to the mass ratio of (25-35): (65-75) to generate a PLA-PEG (Polylactic Acid-Polyethylene Glycol) copolymer as a capsule wall material; mixing the two solutions, and performing ultrasonic emulsification, atomization, drying and cooling to obtain the antibacterial microspheres. Dissolving in RO-grade water to form a solution, and dipping, dehydrating and drying the fabric to obtain a finished product. According to the method, the activity of the bacteriostatic agent and the stability of the microspheres are guaranteed by accurately controlling technological parameters, and the prepared fabric is uniform and lasting in bacteriostatic effect, is suitable for preparation of daily necessities such as soft cotton towels and wet tissues, and has both safety and industrial suitability.
Owner:JIANGSU YUNZHI MEDICAL TECHNOLOGY CO LTD

Phacoemulsification aspiration sleeve for intraocular and extraocular penetration and perfusion confirmation of glaucoma tube surgery

ActiveKR102991524B1ConjunctivaAqueous humor
The present invention relates to an ophthalmic ultrasonic emulsification sleeve for confirming intraocular and extraocular penetration and perfusion, which allows determining whether aqueous humor communication between the inside and outside of the eye is smooth through a microtube implanted in the eye during glaucoma tube surgery. The sleeve is characterized by having a rigid branch tube made of a material harder than a sleeve made of a soft material, provided in a perfusion port that allows the injection of a balance salt solution into the eye, and with the branch tube connected to the perfusion port, the tip of the branch tube protrudes further than the tip of the Paco tip, and the end of the microtube inside the eye is connected to the tip of the branch tube, so that the establishment of aqueous humor communication of the microtube can be quickly and accurately and sensorially confirmed based on the pattern of pressure change in the conjunctival area and surrounding blood flow change that occurs when the balance salt solution leaks out of the eye.
Owner:THE CATHOLIC UNIV OF KOREA IND ACADEMIC COOP FOUND

Nano-emulsion for preventing and treating grain storage pest prymaria rugosoannulata as well as preparation method and application of nano-emulsion

PendingCN121176449ABiocideEdible seed preservationBiotechnologyFood reserve
The invention relates to the technical field of green prevention and control of stored grain pests, in particular to a nano-emulsion for preventing and controlling stored grain pests, namely panonychus rustinae, as well as a preparation method and application of the nano-emulsion. According to the preparation method of the nano-emulsion provided by the invention, the dispersing capacity and the stability of the garlic essential oil in water are improved through embedding of the natural tea saponin; meanwhile, a low-temperature ultrasonic emulsification technology is adopted, so that the activity loss of essential oil is effectively avoided. The preparation process is simple, the prepared nano-emulsion adopts the tea saponin and the garlic essential oil to achieve a synergistic effect, the control efficiency can be effectively improved, the contact killing rate of the nano-emulsion on prymaria rugosa is larger than or equal to 97%, and the fumigation death rate is larger than or equal to 98%. Meanwhile, the tea saponin and the plant essential oil are adopted as core components of the nano-emulsion, the components are natural, the environmental safety is high, and the risk that residues exceed the standard is avoided, so that an industrialized feasible solution can be provided for a green grain storage technology, and the nano-emulsion is particularly suitable for closed / semi-closed storage scenes such as grain storage warehouses, farm granaries and household granaries.
Owner:HENAN UNIVERSITY OF TECHNOLOGY

A method for the preparation of modified anthracene oil for carbon black production

ActiveCN121571084BPigmenting treatmentLiquid-gas reaction as foam/aerosol/bubblesAnthraceneUltrasonic emulsification
This application provides a method for preparing modified anthracene oil for carbon black production, comprising the following steps: Step S1: Introducing ozone into the anthracene oil for ultrasonic emulsification to obtain an emulsion mixture, wherein: ultrasonic frequency: 20–40 kHz; ultrasonic power density: 0.5–0.8 W / cm³ 2 Ultrasonic working time: 1–1.5 h; bubble residence time: 10–15 s; bubble diameter: 50–100 μm; O3 / anthracene oil gas-liquid volume ratio: 0.1–0.3:1; Step S2: The emulsified mixture is alternately subjected to mechanical stirring and ultrasonic emulsification, wherein: ultrasonic frequency: 40–70 kHz; ultrasonic power density: 0.8–1.2 W / cm³ 2 O3 / anthracene oil gas-liquid volume ratio: 0.3–0.5:1; bubble diameter: <30 μm; total working time for mechanical stirring and ultrasonic emulsification: 1.5–2 h. Step S3: Dehydration to obtain modified anthracene oil. The modified anthracene oil obtained in this application has good compositional uniformity, is not prone to stratification, and has few by-products, thus meeting the requirements for raw materials in the production of high-quality carbon black.
Owner:NINGXIA XITAI COAL CHEM CO LTD

Refreshing essential oil formula containing blended bergamot and orange peel oil

The invention provides a formula of refreshing essential oil containing blended bergamot and orange peel oil, and relates to the technical field of essential oil preparation. The invention discloses refreshing essential oil and a preparation method thereof, and aims to solve the technical problem that existing refreshing essential oil is difficult to consider safety, functionality and use convenience at the same time. The formula comprises the following components in parts by weight: core components: 3-12 parts of bergamot oil, 5-15 parts of orange peel oil, 60-85 parts of base oil, 0.5-3 parts of rosemary essential oil which can optionally contain a synergistic component, and 0.1-0.8 part of an antioxidant which is an auxiliary material. Wherein the bergamot oil is extracted by cold pressing, the temperature is less than or equal to 30 DEG C, impurities are less than or equal to 0.5%, and linalyl acetate is more than or equal to 35%; the orange peel oil is filtered after cold pressing, the impurity content is less than or equal to 0.3%, and the limonene content is more than or equal to 90%; the acid value of the base oil is less than or equal to 1.0 mgKOH / g, and the peroxide value is less than or equal to 5.0 meq / The preparation process comprises the steps of raw material pretreatment, component mixing, ultrasonic emulsification, standing and filtering. The product is suitable for office and driving scenes, the release half-life period of volatile components is 4-6 h, the product does not contain artificially synthesized essence, and the peak value ratio of limonene to linalyl acetate detected by gas chromatography is 2.5-4.0.
Owner:GUANGZHOU DINGJIN TECH CO LTD

Responsive release microcapsules, methods of making and using the same

The present application relates to the technical field of wound care, and in particular to a responsive release microcapsule and a preparation method and application thereof.The preparation method comprises the following steps: S1, dissolving polylactic acid-glycolic acid copolymer in an organic solvent, adding an emulsifier, and ultrasonic emulsification to form a water-in-oil emulsion; S2, mixing a polyphenol compound, elastin, vegetable fat and a probiotic bacteria suspension to form a four-component mixed solution, and slowly adding the four-component mixed solution to the water-in-oil emulsion, continuing ultrasonic emulsification to form a multiple emulsion, evaporating and removing the organic solvent to obtain a four-component active ingredient mixed solution; S3, dissolving PDMAEMA in deionized water, adding a crosslinking agent and stirring, slowly adding the four-component active ingredient mixed solution, crosslinking reaction and freeze-drying to obtain the responsive release microcapsule.The microcapsule can release corresponding active ingredients according to the pH value change in different stages of wound healing, effectively shorten the wound healing time, improve the healing quality, and reduce scar formation.
Owner:SHAANXI BAIJI BIOLOGICAL RESEARCH & DEVELOPMENT CO LTD

Preparation method of nano essential oil slow-release patch with self-heating function

The invention relates to a preparation method of a nano essential oil slow-release patch with a self-heating function, and belongs to the technical field of health-care patches. Adding iron powder, activated carbon, sodium chloride and vermiculite into deionized water, stirring, and coating the base material layer with the mixture to form a spontaneous heating layer; the preparation method comprises the following steps: adding essential oil into an acetic acid solution of chitosan, performing ultrasonic emulsification, and dripping into a sodium alginate aqueous solution to obtain nano essential oil microspheres; adding sodium carboxymethyl cellulose and polyvinyl alcohol into deionized water, and adding plant-based linolenic anhydride, soybean protein isolate, a green tea extract and nano essential oil microspheres to obtain a composite glue solution; coating the surface of the self-heating layer with the composite glue solution to form a nano essential oil slow-release layer; uniformly coating the nano essential oil slow-release layer with a pressure-sensitive adhesive, covering the nano essential oil slow-release layer with release paper, cutting, sealing and packaging to obtain the nano essential oil slow-release patch with the self-heating function. The patch prepared by the invention can prolong the heating time and slow release time of the essential oil, and the patch has a remarkable effect of relieving muscular soreness.
Owner:HANGZHOU RED CROSS HOSPITAL (ZHEJIANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL ZHEJIANG UNIVERSITY OF TRADITIONAL CHINESE & WESTERN MEDICINE)

Wax oil hydrocracking catalysts, their preparation and use

This invention discloses a wax oil hydrocracking catalyst, its preparation, and its application. The catalyst mainly comprises the following components by weight: 1-30 parts of mesoporous-microporous SBA-15 / HY composite molecular sieve; 15-40 parts of amorphous silica-alumina; 5-30 parts of mesoporous alumina; 10-30 parts of oxides of metal W or Mo; 1-8 parts of oxides of metal Co or Ni; 1.0-5.0 parts of extrusion aid; and 3-8 parts of binder. The mesoporous-microporous SBA-15 / HY composite molecular sieve is prepared under ultrasonic emulsification. The wax oil hydrocracking catalyst provided by this invention can operate stably for long periods when processing inferior wax oil feedstock.
Owner:PETROCHINA CO LTD

Configurable ultrasonic transducer

An ultrasonic transducer is described having a resonant horn and piezoelectric elements arranged to impart vibration to the horn. The piezoelectric elements are wedge-shaped with respect to a central axis of the horn and arranged on the horn to impart to a distal end of the horn in a longitudinal direction vibration with respect to the central axis and / or a transverse direction vibration with respect to the central axis. Configurations are also described having additional wedge-shaped piezoelectric elements that may impart vibration in a second transverse direction with respect to the central axis. A phacoemulsification probe is described including wedge-shaped piezoelectric elements. Methods for energizing the piezoelectric elements are also described.
Owner:JOHNSON & JOHNSON SURGICAL VISION INC

Magnesium metal / PLGA-TCP composite porous microsphere bone repair material and preparation method thereof

The invention relates to the field of oral alveolar bone repair materials, provides a magnesium metal / PLGA-TCP composite porous microsphere bone repair material and a preparation method thereof, and aims to solve the problems that in the prior art, magnesium ion release is uncontrollable, corrosion is accelerated due to the fact that PLGA is degraded to produce acid, and a microsphere hole structure is single. According to the technical scheme, the preparation method comprises the following steps: dispersing metal magnesium microspheres and beta-tricalcium phosphate in dichloromethane, then adding PLGA and ethyl cellulose, stirring and dissolving to form an oil phase solution, taking a polyvinyl alcohol solution as an outer water phase, dissolving gelatin in part of the polyvinyl alcohol solution as an inner water phase, dropwise adding the inner water phase into the oil phase, and carrying out dual-power ultrasonic emulsification to form a primary emulsion; magnesium metal / PLGA-TCP composite microspheres are prepared through a microfluidic device, the microspheres are solidified and then subjected to water bath to remove gelatin, and then freeze drying is conducted to obtain the multistage through hole microspheres which are used for preparing an oral cavity alveolar bone repair material.
Owner:GUANGXI MEDICAL UNIVERSITY

Phacoemulsification handle with sensor and surge control system and method

An ultrasonic phacoemulsification handpiece with a sensor and a surge control system and a method. The central aspiration lumen of the ultrasonic phacoemulsification handpiece consists of two components of plug-in loose fit: a fixed lumen and an extension lumen; a small pressure sensor is mounted on the extension lumen, but still able to keep the easy-to-use size and maintain the ultrasonic performance of the handpiece. The extension lumen minimizes the effect of ultrasonic vibration on the sensor while maintaining sufficient stiffness for installing and removing the phacoemulsification tip. The design of the handpiece transducer reduces the effect of this sensor installation on the ultrasonic performance. For ultrasonic phacoemulsification cataract removal surgery, the short distance from the pressure sensor to the surgical site provides a technical solution for reliably controlling the risk of the post occlusion surge.
Owner:INNOLCON MEDICAL TECHNOLOGY (SUZHOU) CO LTD

Method for detecting cornea thickness after cataract ultrasonic emulsification operation based on anterior segment OCT (optical coherence tomography)

The invention discloses a cataract ultrasonic emulsification postoperative cornea thickness detection method based on anterior segment OCT, and relates to the technical field of image analysis. The method comprises the following steps: dividing a cornea into a plurality of first regions based on a region growing algorithm and initial cornea thickness data; acquiring a second area based on each first area; acquiring a plurality of partial boundaries based on the second region; based on the boundaries of all the parts, a fibrosis area is obtained; and adjusting the scanning density and the refractive index of the second region based on the fibrosis region and the scanning density correction coefficient to finally obtain cornea thickness data. According to the method, the scanning density and the refractive index of the second area are adjusted by combining the fibrosis area and the scanning density correction coefficient, so that the error of calculation by using a unified refractive index in the prior art is avoided, accurate measurement of the cornea thickness is finally realized, and the technical problem that the thickness of the cornea area cannot be accurately measured through existing OCT detection is solved.
Owner:GUIZHOU YIDAN HENGRUI PHARM TECH CO LTD +1

Swing type ultrasonic emulsification handle

PendingCN121154359AEye surgeryUltrasonic emulsificationCorneal endothelium
The invention provides a swing type ultrasonic emulsification handle, and relates to the field of medical instruments. The swing type ultrasonic emulsification handle comprises a handle shell and an ultrasonic vibrator, the ultrasonic vibrator is arranged in the handle shell, and the ultrasonic vibrator comprises an amplitude-change pole, a left piezoelectric ceramic stack, a right piezoelectric ceramic stack, a rear balance weight and a connecting piece. At least one part of the connecting piece is connected with the rear balance weight, penetrates through the left piezoelectric ceramic stack and the right piezoelectric ceramic stack and then is connected with the amplitude-change pole, one end of the ultrasonic vibrator is fixedly connected with a handle cable, and the handle cable penetrates through the handle shell. According to the ultrasonic emulsification handle, the vibration heating energy in the ultrasonic emulsification process can be reduced, the damage to the capsular membrane and the corneal endothelium is reduced, the complication occurrence rate is reduced, meanwhile, the structure of the ultrasonic vibrator can be simplified, and the manufacturing cost and the maintenance difficulty are reduced.
Owner:WUHAN TONGRUI TECHNOLOGY CO LTD

Lung-moistening snow pear paste containing radix astragali and rhizoma atractylodis macrocephalae and preparation method thereof

The invention discloses lung-moistening snow pear paste containing radix astragali and rhizoma atractylodis macrocephalae and a preparation method of the lung-moistening snow pear paste, and belongs to the technical field of health care product processing. Aiming at the component characteristics of astragalus membranaceus, atractylodes macrocephala koidz and divaricate saposhnikovia root, three targeted extraction modes of ultrasonic, microwave and reflux are respectively adopted, and macroporous adsorption resin purification is combined, so that the effective components of astragalus polysaccharide, atractylenolide and divaricate saposhnikovia root are reserved to the maximum extent, and the extraction rate is obviously improved compared with that of a traditional water boiling method; the core matrix is subjected to high-pressure homogenization and particle refining, and the traditional Chinese medicine effective components and the matrix are subjected to ultrasonic emulsification to realize molecular-level fusion, so that the problems of poor compatibility and easy layering of the traditional Chinese medicine components and the matrix in the traditional process are solved, the pasty fluid fineness is improved, and the pasty fluid tastes smooth and has no granular sensation; through cooperative use of the stabilizer and then vacuum low-temperature concentration, damage to heat-sensitive components is avoided, and the storage time of the product is prolonged.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

Chinese prickly ash seed oil emulsion for low-fat food as well as preparation method and application of Chinese prickly ash seed oil emulsion

The invention relates to a Chinese prickly ash seed oil emulsion for low-fat food and a preparation method and application thereof, and the preparation method comprises the following steps: 1) ethanol extraction of Chinese prickly ash seed oil: drying Chinese prickly ash seeds until the moisture content is below 10%, crushing, sieving, degreasing and drying; taking absolute ethyl alcohol as a solvent, performing constant-temperature extraction and filtration to obtain a mixed solution of crude Chinese prickly ash seed oil and ethyl alcohol, and performing rotary evaporation to remove ethyl alcohol to obtain Chinese prickly ash seed oil; 2) preparation of a chickpea protein solution: preparing a 10 mg / mL chickpea protein solution by using deionized water, and stirring to obtain the chickpea protein solution; 3) ultrasonic emulsification: mixing the Chinese prickly ash seed oil with the chickpea protein solution; an ultrasonic probe is immersed in a position 1.5 cm away from the upper surface of the emulsion for ultrasonic treatment, ice-water bath temperature control is performed in the whole emulsification process, protein denaturation caused by local overheating is avoided, and the treated product is stored at 4 DEG C; according to the preparation method, the emulsification efficiency is remarkably improved, the emulsification time is shortened to 15 min through the ultrasonic cavitation effect, and particle size distribution is uniform.
Owner:HEFEI UNIV OF TECH