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477 results about "Polyglutamic acid" patented technology

Polyglutamic acid (PGA) is a polymer of the amino acid glutamic acid (GA). Gamma PGA (Poly-γ-glutamic acid, γ-PGA) - the form where the peptide bonds are between the amino group of GA and the carboxyl group at the end of the GA side chain - is a major constituent of the Japanese food nattō. Gamma PGA is formed by bacterial fermentation.

Special charcoal-based slow-release fertilizer for sandy soil as well as preparation method and application of special charcoal-based slow-release fertilizer

The invention provides a special charcoal-based slow-release fertilizer for sandy soil as well as a preparation method and application thereof, and belongs to the technical field of fertilizers. The special charcoal-based slow-release fertilizer for the sandy soil is prepared from amino modified biomass charcoal, urea, urea formaldehyde, monoammonium phosphate, potassium sulfate, polyglutamic acid, fulvic acid, clay, attapulgite, a compound microbial agent and sodium alginate. The compound microbial agent is prepared from halomonas (ACCC 11681), bacillus subtilis (ACCC 60429) and bacillus mucilaginosus (ACCC 10094), and the compound microbial agent is prepared from bacillus subtilis (ACCC 60429) and bacillus mucilaginosus (ACCC 10094). The invention further provides a preparation method and application of the special charcoal-based slow-release fertilizer for the sandy soil. The special charcoal-based slow-release fertilizer for the sandy soil can remarkably improve the water and fertilizer retention capacity of the sandy soil, improve the farmland productivity of the sandy soil, save fertilizer and water input and improve the yield and quality of crops.
Owner:XINYANGFENG AGRI TECH CO LTD +1

Preparation method of antibacterial gamma-polyglutamic acid superabsorbent hydrogel

The invention relates to a preparation method of antibacterial gamma-polyglutamic acid superabsorbent hydrogel. The preparation method comprises the following steps: (1) preparing a gamma-polyglutamic acid solution; (2) dissolving an antibacterial agent in the gamma-polyglutamic acid solution, and fully stirring and uniformly mixing to obtain a mixed solution 1; adjusting the pH value of the mixed solution 1, heating the mixed solution 1 to 60 DEG C, and continuously reacting for 1-2 hours to obtain a mixed solution 2; cooling the mixed solution 2 to room temperature, adding a cross-linking agent, and uniformly mixing to obtain a mixed solution 3; standing the mixed solution 3 at room temperature for 1-3 hours and then carrying out gradient heating reaction to obtain an antibacterial gelatinous product; and (3) dehydrating the antibacterial gelatinous product, and carrying out vacuum negative pressure drying to obtain a dried hydrogel product, namely the antibacterial gamma-polyglutamic acid super absorbent hydrogel. The antibacterial gamma-polyglutamic acid superabsorbent hydrogel prepared by the invention has good biocompatibility, is safe and non-toxic, also has excellent water absorption performance and antibacterial performance, and has a good application prospect.
Owner:DONGHUA UNIV

Environment-friendly water-soluble fertilizer containing seaweed extract and polyglutamic acid

The invention relates to the technical field of fertilizers, in particular to an environment-friendly water-soluble fertilizer containing a seaweed extract and polyglutamic acid. The water-soluble fertilizer is prepared by preparing seaweed oligosaccharide and double-grafted poly-L-gamma-sodium glutamate and compounding and complexing the seaweed oligosaccharide and the double-grafted poly-L-gamma-sodium glutamate, has the characteristics of low salting-out, high stability, no precipitation, good slow release performance and the like, and can continuously release nutrients and keep a solution clear and transparent under a low-salt condition; and because the polyglutamic acid and seaweed extract compound drip irrigation agent has the chelation and water retention characteristics of the polyglutamic acid and the natural growth promoting effect of the seaweed extract, the crop rhizosphere nutrient absorption efficiency and stress resistance are remarkably improved, the compound drip irrigation agent is suitable for drip irrigation and water and fertilizer integrated application of greenhouse vegetables, fruit trees and field crops, and the comprehensive effects of high efficiency, low salt load and environment friendliness are achieved.
Owner:SHANDONG JIAKE PLANT NUTRITION ENG CO LTD

High-elasticity moisture-absorption breathable acetate fabric and preparation method thereof

The invention relates to the technical field of textile material and fiber processing, in particular to a high-elasticity moisture-absorption breathable acetate fabric and a preparation method thereof. The invention discloses a high-elasticity moisture-absorption breathable acetate fabric and a preparation method thereof.The acetate fabric takes a bio-based degradable thermoplastic polyester elastomer as an island and acetate as a sea, a homothermal double-hole structure is embedded in the acetate fabric, and the surface of the acetate fabric is covered with a polyglutamic acid and chitosan oligosaccharide self-repairing hydrophilic layer; the preparation method comprises the following steps: pre-burying alkali-resistant microspheres in a marine facies through solid island-solution sea double-path spinning of a bio-based degradable thermoplastic polyester elastomer and acetate, synchronously forming groove-closed pore double channels through simultaneous heating one-step alkali etching-baking, and finally forming a dynamic reversible hydrogen bond network through polyglutamic acid and chitosan oligosaccharide, so as to obtain the marine-based degradable alkali-resistant hydrogel. A bio-based finishing layer with a self-repairing function is obtained, and the finally obtained fabric has the characteristics of high elasticity, breathability, lasting moisture absorption, greenness and degradability.
Owner:WUJIANG HENGXIN WEAVING CO LTD

Method for detecting activity of gamma-polyglutamic acid hydrolase and application

The invention relates to a method for detecting activity of gamma-polyglutamic acid hydrolase and application. The method comprises the following steps: (1) preparing an enzymolysis reaction solution and a blank reaction solution; (2) preparing an NAC / OPA mixed solution; (3) adding an NAC / OPA mixed solution into the enzymatic hydrolysis reaction solution to obtain a reaction solution to be detected; (4) drawing a standard curve by taking L-glutamic acid as a standard substance; and (5) detecting the fluorescence intensity of the blank reaction solution and the reaction solution to be detected by using a microplate reader, and then calculating the activity of the gamma-polyglutamic acid hydrolase according to the fluorescence intensity and the standard curve. The method for detecting the activity of the gamma-polyglutamic acid hydrolase is high in detection speed, detection of a single sample can be completed within 25 min, and nearly real-time process monitoring is achieved. And the method has the advantages of reliable detection result and high accuracy, can be used for monitoring the enzyme activity of the gamma-polyglutamic acid hydrolase in the gamma-polyglutamic acid preparation process in real time and guiding the optimization of the fermentation process, and has extremely high industrial application value.
Owner:SHANDONG FENGJIN MEIYE TECH CO LTD

Red soil hardening reduction conditioner based on modified straw adsorption carbon as well as preparation method and application thereof

The invention relates to the technical field of agriculture, provides a red soil hardening reduction conditioner based on modified straw adsorption carbon as well as a preparation method and application thereof, and solves the problems that an existing red soil hardening conditioner is poor in soil improvement effect and does not have a slow release function. Comprising the following steps: (1) preparing oyster shell-biochar composite powder; (2) loading functional components; (3) directional immobilization of microorganisms; (4) coating a slow-release layer; (5) activating treatment; the red soil hardening reduction conditioner is prepared from the following raw materials in parts by weight: 80 to 100 parts of oyster shell powder, 100 to 200 parts of modified straw adsorption carbon, 10 to 30 parts of rice hull powder, 30 to 50 parts of nano dihydrate gypsum, 100 to 200 parts of a polyglutamic acid solution, 10 to 50 parts of acid-resistant bacillus, 15 to 30 parts of sodium alginate, 30 to 60 parts of humic acid, 10 to 30 parts of carbide slag and 30 to 60 parts of attapulgite.
Owner:QUANZHOU MATA ECOLOGICAL TECH CO LTD +1

Organic-inorganic composite silicon-calcium-magnesium fertilizer as well as preparation method and application thereof

The invention relates to the technical field of agricultural fertilizers, in particular to an organic-inorganic composite silicon-calcium-magnesium fertilizer and a preparation method and application of the organic-inorganic composite silicon-calcium-magnesium fertilizer. The high-temperature activated silicon-calcium-magnesium mineral powder is composed of calcined wollastonite powder, calcined serpentine powder, dolomite powder and zeolite powder; 2%-5% of an organosilane modifier, wherein the organosilane modifier is composed of gamma-aminopropyl triethoxy silane and gamma-glycidyl ether oxypropyl trimethoxy silane, and the organic silane modifier is composed of gamma-aminopropyl triethoxy silane and gamma-glycidyl ether oxypropyl trimethoxy silane; 18%-35% of a functional organic matter complex, wherein the functional organic matter complex is composed of mineral source sodium humate, bioactive small peptide, sodium alginate and polyglutamic acid; and 3%-8% of auxiliary functional components, so that the solubility and the bioavailability of silicon, calcium and magnesium elements in minerals are remarkably improved.
Owner:YISI (HEILONGJIANG) BIOTECHNOLOGY DEVELOPMENT CO LTD

Cellulose-chitosan-based lithium ion battery diaphragm as well as preparation method and application thereof

The invention relates to a cellulose-chitosan-based lithium ion battery diaphragm and a preparation method and application thereof.The preparation method of the diaphragm comprises the steps that gamma-polyglutamic acid and polyamide epichlorohydrin are adopted for modifying chitosan, the hydrophilicity and the liquid absorption capacity of the chitosan are improved, polyvinylpyrrolidone is adopted for coating the chitosan, and the hydrophilicity and the liquid absorption capacity of the chitosan are improved; pVP is replaced in ethanol soaking to form micropores, so that the porosity of the modified chitosan is improved. Amino groups and hydroxyl groups of the modified chitosan are combined with catechol of the polydopamine and hydroxyl groups of the hydroxy propyl cellulose through hydrogen bonds and covalent bonds to form a chitosan-cellulose-PDA interpenetrating network, and the diaphragm material suitable for the lithium ion battery is finally prepared by combining hot-pressing shaping. The preparation method has the advantages that the balance between the mechanical property and the ion conduction property of the diaphragm is realized through multi-component compounding by utilizing the biocompatibility and renewability of natural macromolecules (cellulose and chitosan).
Owner:GUANGDONG YINGTONG PAPER CO LTD

Low-pressure high-flux polyamide / polysulfone hollow fiber composite nanofiltration membrane and preparation method thereof

The invention belongs to the technical field of membrane separation, and particularly relates to a low-pressure high-flux polyamide / polysulfone hollow fiber composite nanofiltration membrane and a preparation method thereof. The preparation method of the composite nanofiltration membrane comprises the following steps: dissolving sulfonated polysulfone, poly (1-vinyl-3-butylimidazole) bromide and polyvinylpyrrolidone to prepare a spinning solution, and spinning to obtain a base membrane; carrying out hydrophilic modification on the base membrane by using 1, 3-propane sultone; then, an aqueous phase solution containing poly (gamma-glutamic acid) and triethylene tetramine and an organic phase solution containing trimesoyl chloride and 3, 5-diaminobenzoic acid are subjected to interfacial polymerization in the inner cavity of the modified base membrane to form a polyamide separation layer; and finally, carrying out heat treatment to obtain the composite nanofiltration membrane. Through the synergistic effect of zwitterionic ionization of the base membrane and biomacromolecule construction of the separation layer, the mass transfer resistance of water is remarkably reduced, unification of high flux and high selectivity is achieved, and good structural stability is achieved.
Owner:BEIJING BEIPAI MEMBRANE TECH CO LTD +1

Synergistic monoammonium phosphate fertilizer containing seaweed as well as preparation method and application of synergistic monoammonium phosphate fertilizer

The invention relates to the technical field of fertilizers, in particular to a seaweed-containing synergistic monoammonium phosphate fertilizer as well as a preparation method and application thereof. The preparation method comprises the following steps: mixing a seaweed extract with beta-cyclodextrin, performing microencapsulation, and performing spray drying to obtain an embedded material; mixing with monoammonium phosphate and polyglutamic acid, and granulating; spraying salt-resistant compound bacteria liquid on the surfaces of the particles; and finally, coating the particles with a chitosan-sodium alginate composite film. According to the prepared synergistic monoammonium phosphate fertilizer finished product, the phosphorus utilization rate of monoammonium phosphate saline-alkali soil can be increased, the phosphorus fixation rate can be greatly reduced, the retention rate of active ingredients of the seaweed extract is greatly increased compared with that in the prior art, the rhizosphere survival rate of salt-tolerant flora is greatly increased, and the salt-tolerant flora, the seaweed extract and monoammonium phosphate cooperate to promote crop yield increase.
Owner:XINYANGFENG AGRI TECH CO LTD +1

Special silicon-containing compound fertilizer for lodging resistance and disease prevention of rice and preparation method of special silicon-containing compound fertilizer

The invention relates to the technical field of compound fertilizers, and discloses a silicon-containing compound fertilizer special for lodging resistance and disease prevention of rice and a preparation method thereof.The silicon-containing compound fertilizer is prepared from 30-35 parts of organic compound matrix, 20-26 parts of straw liquefied matter, 5-10 parts of water-soluble silicon fertilizer, 4-8 parts of humic acid, 1-1.5 parts of microbial agent, 0.5-0.8 part of polyglutamic acid, 5-10 parts of compound coating liquid and 0.2-0.5 part of microelement chelate, the composted duck manure, the peat and the coco coir are used as main raw materials, the air permeability of the peat is combined with nutrients of the duck manure, soil hardening can be improved, soil fertility can be improved, the water-soluble silicon fertilizer is matched with the organic compound matrix, absorption of silicon elements by rice is promoted, a silicified cell layer is formed on the stem epidermis, then the cell wall thickness is increased, and the rice yield is increased. The breaking strength of the stalks is improved.
Owner:HUBEI EZHONG ECOLOGICAL ENG CO LTD

Symmetric nucleoside microneedle patch loaded with polymer vesicles as well as preparation method and application of symmetric nucleoside microneedle patch

The invention discloses a symmetric nucleoside microneedle patch loaded with polymer vesicles as well as a preparation method and application of the symmetric nucleoside microneedle patch. The symmetric nucleoside microneedle patch loaded with the polymer vesicles comprises a guanosine-quadruplex hydrogel microneedle tip doped with drug-loading polymer vesicles, the raw material of the drug-loaded polymer vesicle comprises a polycaprolactone-polyglutamic acid copolymer; the guanosine-quadruplex hydrogel is prepared from the following raw materials: guanosine and KB (OH) 4. The microneedle patch is constructed on the basis of dynamic covalent bond and non-covalent interaction, has a sharp tip array capable of penetrating the epithelium and the lower layer of a mucous membrane, can efficiently deliver a drug to a canker lesion part by bypassing a mucous membrane barrier, can be controllably broken under a high ROS condition of an inflammation microenvironment, has the characteristics of high drug delivery efficiency and high accuracy, and can be used for preparing a medicine for treating the canker lesion part. The effect of effectively improving chemotherapy-induced oral ulceration can be achieved by reducing inflammatory response, relieving pain feeling and inhibiting pain sensitization.
Owner:SHANGHAI FOURTH PEOPLES HOSPITAL

Polysaccharide yeast chelating synergist suitable for fertilizer and application thereof

The invention belongs to the technical field of fertilizer synergists, and particularly relates to a polysaccharide yeast chelating synergist suitable for fertilizers and application of the polysaccharide yeast chelating synergist. The polysaccharide yeast chelating synergist suitable for the fertilizer is prepared from the following raw materials in parts by weight: 10 to 25 parts of polyglutamic acid, 1 to 5 parts of zymosan, 8 to 15 parts of modified polyacrylamide, 8 to 12 parts of sodium humate, 1 to 5 parts of trace elements, 5 to 10 parts of filler and 6 to 10 parts of organic acid. By adding the modified polyacrylamide, the zymosan, the filler and other components into the polyglutamic acid, the fertilizer retention capacity and slow release performance of the fertilizer are effectively improved, and the yield and quality of crops are further improved.
Owner:BEIJING JIAHUI DECHEN TECHNOLOGY CO LTD +1

Repair compositions and uses thereof

The invention provides a repairing composition and application thereof. The repairing composition at least comprises the following components: (1) polydeoxyribonucleotide; (2) gamma-polyglutamic acid or a salt thereof; and (3) hyaluronic acid or salts thereof, and the three components of polydeoxyribonucleotide, gamma-polyglutamic acid or salts thereof and hyaluronic acid or salts thereof in the repairing composition are compounded to achieve a synergistic effect, so that the repairing composition is beneficial to improving skin sensitivity, repairing skin barriers, stimulating collagen regeneration and the like.
Owner:BLOOMAGE BIOTECHNOLOGY CORP LTD

High-absorptivity sanitary napkin core material

The invention relates to the field of functional materials, and discloses a high-absorptivity sanitary napkin core material which is prepared from the following components in parts by mass: 30-35 parts of spiral nano cellulose; 20 to 25 parts by mass of a polyglutamic acid-polylysine grafted copolymer; 0.5 to 1.5 parts by mass of a thiodipropionic acid cross-linking agent; the helical angle of the helical nanocellulose is 25-35 degrees, the diameter of the helical nanocellulose is 5-10 nm, the specific surface area of the helical nanocellulose is greater than or equal to 300 m < 2 > / g, in the polyglutamic acid-polylysine grafted copolymer, the grafting rate of polylysine is 15-25%, the molecular weight of the polylysine is 3-5 kDa, the particle size of the nano-zinc oxide is 20-30 nm, the surface of the nano-zinc oxide is subjected to hydroxylation modification, and the surface of the nano-zinc oxide is 20-30 nm. The nano zinc oxide and the spiral nano cellulose are combined through a hydrogen bond and Van der Waals force, and the combination energy is greater than or equal to 25kJ / mol. By adopting the spiral angle and gradient pore design of the spiral nanocellulose, the technical effect of synergistic enhancement of liquid directional diversion and bottom layer latching is achieved.
Owner:雷文军 +1

Sand-fixing and water-retaining agent and method for preventing and repairing grassland desertification by using same

The invention relates to a sand-fixing and water-retaining agent and a method for preventing and repairing grassland desertification by using the same. The sand-fixing and water-retaining agent is mainly prepared by compounding the following components: polyglutamic acid, a compound biological enzyme preparation and compound vitamins. The method comprises the following steps: (1) enclosing: enclosing a potential desertification grassland area and forbidding grazing; (2) spraying a water-retaining agent and sowing grass seeds: blending the sand-fixing and water-retaining agent with water according to the size of a potential desertification grassland area in summer of the first year, and immediately sowing the grass seeds after spraying operation; and (3) recuperating: repeating the operation of the step (2) within 2-4 years from the next year, and reseeding grass seeds in an area which is not recovered in the previous year. The sand-fixing and water-retaining agent is friendly to grassland environment, harmless to animals and plants and low in cost. The method disclosed by the invention is simple and convenient to operate, the pasture grows and recovers quickly, and the purpose of preventing grassland desertification is achieved.
Owner:CHENGDU HUAHONG ECOLOGICAL AGRI TECH CO LTD

Preservative for preventing durian from cracking and preparation method thereof

The invention discloses a preservative for preventing durian from cracking and a preparation method thereof, and mainly relates to the technical field of fruit preservation. Compared with the prior art, the chitosan is used as a main component and cooperates with the acetic acid, the polyglutamic acid, the sodium alginate, the sorbitol, the plant polyphenol nanoparticle emulsion and the compound gum such as the konjac gum, the carrageenan and the xanthan gum to act together, and the plant polyphenol nanoparticle emulsion obtained by a special preparation method is added; when the preservative film is applied to the surface of the durian, a layer of preservative film can be formed, and finally the technical purposes of improving the water locking performance and puncture resistance, reducing the weight loss rate, preventing the durian from cracking and prolonging the preservation period are achieved.
Owner:JIUKE BIOTECHNOLOGY (YUNNAN) CO LTD

Multi-element conditioning fertilizer suitable for acid soil and preparation method of multi-element conditioning fertilizer

The invention discloses a multi-element conditioning fertilizer suitable for acid soil and a preparation method thereof, and the multi-element conditioning fertilizer suitable for acid soil comprises the following components by mass: 8-18 parts of diatomite; 20 to 30 parts of calcium humate; 25-35 parts of a silicon calcium magnesium phosphate fertilizer; 10 to 20 parts of chitosan modified humic acid; 5-10 parts of amino acid chelated medium trace elements; 15 to 25 parts of a biochar-based complex microbial inoculant; 3-8 parts of modified zeolite; 3-8 parts of polyglutamic acid; the multi-element conditioning fertilizer suitable for the acid soil contains various innovative components, chitosan modified humic acid improves the stability and adsorption performance of humic acid, amino acid chelated medium trace elements improves the absorption and utilization rate of the medium trace elements, polyglutamic acid enhances the water and fertilizer retention capacity of the fertilizer, and the water and fertilizer retention capacity of the fertilizer is improved. The diatomite and the modified zeolite significantly increase the porosity of the soil and improve the air permeability and drainage of the soil, and the components cooperate with each other, so that the physicochemical properties and biological activity of the acid soil can be comprehensively adjusted.
Owner:QINGDAO ATOP AGRI TECH CO LTD

Polyglutamic acid granular fertilizer and preparation method thereof

The invention provides a polyglutamic acid granular fertilizer and a preparation method thereof, and the preparation method comprises the following steps: S1, dissolving lignin in an alkaline solution, and heating until the lignin is dissolved; adding epsilon-polylysine fermentation liquor, mixing, heating, adding a formaldehyde solution, and carrying out grafting reaction to obtain epsilon-polylysine grafted lignin; s2, mixing the epsilon-polylysine grafted lignin solution and the gamma-polyglutamic acid solution, adding N-hydroxysuccinimide, standing at a low temperature, adding 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride, and mixing; carrying out gradient temperature reaction to obtain lignin grafted epsilon-polylysine / gamma-polyglutamic acid hydrogel; and S3, homogenizing the lignin-grafted epsilon-polylysine / gamma-polyglutamic acid hydrogel, carrying out normal-temperature high-pressure airflow crushing, and spraying the crushed hydrogel to the surfaces of particles obtained by granulating a basic material through high-pressure electrostatic spraying, so as to obtain the polyglutamic acid granular fertilizer. The obtained polyglutamic acid granular fertilizer has relatively strong water-retaining and slow-release (releasing water, urea and the like) effects.
Owner:HEILONGJIANG CHENGUANG BIO-ORGANIC FERTILIZER MFG CO LTD

Rapid fertilizing and improving method for newly-reclaimed red soil dry land

The invention relates to the technical field of agricultural resources and environment, and particularly discloses a rapid fertilization improvement method for newly-reclaimed red soil dry land. The method systematically integrates the core steps of soil diagnosis aluminum toxicity passivation, composite conditioner deacidification, two-stage deep ploughing, organic and inorganic biological synergistic fertilization, soil moisture content regulation and control, earth surface covering, green manure planting and returning to the field and the like. The applied composition comprises a soil composite conditioner, a charcoal-based organic fertilizer and a specific functional microbial agent, wherein the soil composite conditioner comprises modified oyster shell powder, a calcium magnesium phosphate fertilizer, humic acid, polyglutamic acid and the like. The method relates to key processes such as temperature programming calcination modification of raw materials, co-pyrolysis and composite granulation of the materials and the like. The method can synchronously and quickly improve the chemical and biological properties of soil and optimize the physical structure of a plough layer, and has the advantages of high improvement targeting, synergistic interaction of all steps, high fertilizing speed and lasting effect; in addition, the method has the advantages of being coherent in process, high in resource utilization efficiency and easy to implement on a large scale.
Owner:INST OF SOIL FERTILIZER & RESOURCE ENVIRONMENT JIANGXI ACAD OF AGRI SCI

Organic-inorganic composite acid soil conditioner with synergism of nitrogen element synergism and soil expansion and application of organic-inorganic composite acid soil conditioner

The invention discloses an organic-inorganic composite acid soil conditioner with synergism of nitrogen element synergism and soil expansion and application, and belongs to the technical field of soil conditioners. The modifier prepared by the invention is prepared from an acid neutralizer, a structure modifier, a capacity expansion synergist and a nitrogen synergist and is prepared from the following components in parts by weight: 18 to 22 parts of dolomite powder, 6 to 10 parts of lime powder, 20 to 24 parts of oyster shell powder, 8 to 12 parts of humic acid, 4 to 8 parts of sargassum, 1 to 3 parts of sodium alginate, 7 to 11 parts of charcoal, 5 to 9 parts of sepiolite powder, 3 to 7 parts of bentonite, 6 to 10 parts of poly gamma-calcium glutamate and 3 to 7 parts of chitosan. The soil conditioner can regulate and control the soil acidity, buffer the soil capacity, improve the soil structure and balance soil nutrients, solves the problems of high re-acidification rate, soil hardening and nutrient imbalance of a traditional lime conditioner, and is suitable for pHlt; and 6.5, repairing the acid soil.
Owner:SHANDONG AGRICULTURAL UNIVERSITY +1

Xanthophyll nano-particles based on electrostatic self-assembly and preparation method of xanthophyll nano-particles

The invention provides a xanthophyll nano-particle based on electrostatic self-assembly, which is formed by electrostatic self-assembly and spontaneous aggregation of polyglutamic acid and chitosan oligosaccharide and embedding of xanthophyll at the same time. The mass ratio of the polyglutamic acid to the chitosan oligosaccharide to the xanthophyll is 4: 600: 3; the particle size of the xanthophyll nanoparticles is 180-250 nm, and the encapsulation efficiency of the xanthophyll nanoparticles is 60-90%; the preparation process comprises the following steps: mixing a polyglutamic acid aqueous solution and a xanthophyll anhydrous alcohol solution, and fully mixing and stirring for later use; dropwise adding the mixed solution into the chitosan oligosaccharide aqueous solution, and fully stirring and mixing to obtain a xanthophyll nanoparticle solution; and removing insoluble xanthophyll, and freeze-drying to obtain the xanthophyll composite nanoparticles.
Owner:TIANJIN BEIYANG BAICHUAN BIOTECHNOLOGY CO LTD

Medical tissue adhesive, medical tissue dry adhesive patch and preparation method and application thereof

The present application relates to the field of medical tissue adhesive, in particular to a medical tissue adhesive, a medical tissue dry adhesive patch and a preparation method and application thereof. The present application provides a medical tissue adhesive, a medical tissue dry adhesive patch and a preparation method and application thereof. The medical tissue adhesive provided by the present application comprises: 1wt%-30wt% of acidic polyglutamic acid; 1wt%-30wt% of spherical protein; and the balance of water. The medical tissue adhesive provided by the present application has high tissue adhesion strength and fast hemostatic sealing speed in a wet physiological environment, meets the requirements of rapid and efficient tissue hemostatic sealing, and can be applied to rapid hemostasis of tissue wounds in a wet physiological environment, sealing of wound liquid leakage, healing and repair of wound tissue, and antibacterial of wounds. Experiments show that the dry adhesive patch made of the adhesive provided by the present application has high tissue adhesion strength in a wet physiological environment, and the adhesion strength to a wet pigskin tissue can reach more than 60kPa.
Owner:CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES

Multi-effect analgesic and anti-inflammatory gel for oral cavity and preparation method thereof

The invention discloses oral multi-effect analgesic and anti-inflammatory gel and a preparation method thereof, and belongs to the technical field of medical gel. The gel is prepared from mussel mucin grafted hydroxypropyl chitosan, a poly (N-isopropylacrylamide)-co-acrylic acid copolymer, quercetin-zinc coordination nanoparticles, a local anesthetic compound wrapped by temperature-sensitive lipidosome, a gamma-polyglutamic acid-catechin gel matrix, aloe polysaccharide, dipotassium glycyrrhizinate, and sodium hyaluronate and potassium sorbate which can be selectively added, wherein the local anesthetic compound is prepared from the mussel mucin grafted hydroxypropyl chitosan, the poly (N-isopropylacrylamide)-co-acrylic acid copolymer, the quercetin-zinc coordination nanoparticles, the temperature-sensitive lipidosome, the gamma-polyglutamic acid-catechin gel matrix, the aloe polysaccharide and the dipotassium glycyrrhizinate. During preparation, part of the components and water are stirred to obtain a mixed solution, and then the other components are added and stirred into gel. According to the gel, the leakage rate of local anesthetics is reduced by stabilizing the liposome through the zinc ions, the quercetin adjusts the phase transition temperature of the liposome to realize preferential drug release at the pain part, the mussel mucin and the copolymer form a reversible hydrogen bond network to enhance the mucous membrane adhesive force, and the inflammatory environment triggers the gel permeation drug release, so that the gel has the advantages of multiple-effect synergy, strong adhesion and the like; the problems that existing oral gel is short in analgesia time and insufficient in anti-inflammation can be effectively solved.
Owner:BEIJING STOMATOLOGY HOSPITAL CAPITAL MEDICAL UNIV

A method for precise fertilization of corn throughout the whole growth period

The present application relates to the technical field of corn fertilization, and provides a corn whole growth period precise fertilization method, which comprises the following steps: S1, applying base fertilizer containing nitrogen fertilizer, phosphorus fertilizer, potassium fertilizer, brown algal polysaccharide, calcium ammonium nitrate, zinc citrate, potassium humate and gamma-polyglutamic acid between corn rows when corn is sowed; S2, spraying leaf fertilizer containing potassium dihydrogen phosphate, magnesium sulfate, alginic acid and polyaspartic acid during the corn filling stage; the base fertilizer is slow-release fertilizer, and after granulation, the base fertilizer is coated with a polyester composite layer and a wax layer in sequence. According to the present application, the base fertilizer is made into double-layer coated slow-release particles and applied with sowing, the outer layer of furfural / wax forms a hydrophobic barrier to inhibit the burst release and salt damage during the seedling stage, and the inner layer of polyester composite layer forms controllable water channels and slowly hydrolyzes with time, so that nutrients are supplied in stages in a platform mode during the corn growth period, and precise fertilization and efficient utilization are achieved during the whole growth period.
Owner:GULANG FAMAX AGRI SERVICE CO LTD

Highly active acid hydrolyzed biochar

The present application belongs to the technical field of biochar, and particularly relates to a high-activity acidolysis biochar, which is prepared by the following steps: S1, pretreating agricultural and livestock waste; S2, acidolysing the pretreated biomass with dilute acid to obtain acidolysed biomass; S3, placing the acidolysed biomass into a high-temperature furnace to perform carbonization under an oxygen-free condition, and using a step-by-step heating mode to obtain preliminary biochar; and S4, mixing the preliminary biochar with a copolymer solution to prepare the high-activity acidolysis biochar. In the present application, the sodium lignosulfonate-polyglutamic acid copolymer forms a stable connection with the biochar through chemical bonding, the porous surface of the biochar is uniformly covered with the copolymer to form a nanoscale film, the composite has stronger complexing, chelating and ion exchange capacity for heavy metal ions and other cations in the soil, and is helpful to reduce toxic substances in the soil and improve the soil environment.
Owner:SHENYANG AGRI UNIV

Composite acidifying agent for improving feed intake of lactating sows and preparation method of composite acidifying agent

The invention relates to a composite acidifying agent for improving feed intake of lactating sows and a preparation method thereof, and belongs to the technical field of feed additives. The composite acidifier comprises a wall material and a core material, wherein the wall material comprises cystine-gamma-polyglutamic acid and arginine-chitosan; the core material comprises organic acid, organic acid salt and fermentation liquor. According to the compound acidifying agent disclosed by the invention, the cystine cross-linked gamma-polyglutamic acid and the arginine grafted chitosan are used as wall materials, and the microcapsule with an intestinal targeted release function is formed by wrapping the organic acid, so that the utilization efficiency of the acidifying agent and the feed intake of lactating sows can be effectively improved.
Owner:GUANGDONG RUIKE NUTRITION TECH CO LTD

Biological organic fertilizer applied to silverweed cinquefoil root planting in saline-alkali soil and preparation method thereof

The invention discloses a bio-organic fertilizer applied to silverweed cinquefoil root planting in saline-alkali soil and a preparation method thereof, and relates to the technical field of bio-organic fertilizers, the bio-organic fertilizer applied to silverweed cinquefoil root planting in saline-alkali soil is prepared from the following raw materials by mass: 40-60 parts of an organic matter carrier including decomposed cattle and sheep manure and corn straw according to a mass ratio of (2-3): 1; 20-30 parts of a saline-alkali soil improver and 0.5-2 parts of microbial flora; 8-15 parts of a functional additive which comprises 3-5 parts of polyaspartic acid calcium salt, 2-4 parts of gamma-polyglutamic acid, 1-2 parts of zinc sulfate and 1-2 parts of borax; 1-3 parts of a slow-release oxygen supply material; the preparation method of the bio-organic fertilizer comprises the following steps: S1, pretreating raw materials; s2, primary fermentation; s3, secondary fermentation; s4, aging and decomposing; s5, carrying out post-treatment; the survival rate of the silverweed cinquefoil root in the saline-alkali soil is greater than 92% and the Na < + > reduction rate of the soil is greater than 40% through directional raw material improvement, staged oxygen supply fermentation, aging decomposition and post-treatment, and an effective solution is provided for economic crop planting in the saline-alkali soil.
Owner:QINGHAI UNIV FOR NATITIES

Ecobiotic composition capable of preventing and treating redness, signs of skin aging and vascular abnormalities

The present invention relates to a cosmetic composition, advantageously an eco-biological cosmetic composition, comprising: - polyglutamic acid or a salt thereof; and - at least one peptide derivative represented by the general formula (I) in which: - R1 represents a hydrogen atom, an acyl radical or an acyloxy radical; and - R2 represents the side chain of an alpha-amino acid chosen from the group consisting of phenylalanine, glutamic acid, arginine, cysteine, methionine, histidine and tyrosine. The present invention also relates to the use of said cosmetic composition for combating skin redness and / or skin aging; to its use for preventing and / or combating cutaneous vascular hyperproliferation and / or cutaneous inflammation and / or rosacea; and to a method for selecting compounds suitable for preventing and / or combating these pathologies.
Owner:NAOS INST OF LIFE SCI +1

Nano drug-loaded particle based on gamma-polyglutamic acid and epsilon-polylysine as well as preparation method and application of nano drug-loaded particle

The invention provides a nano drug-loaded particle based on gamma-polyglutamic acid and epsilon-polylysine, a composite shell is arranged outside the nano drug-loaded particle, the composite shell is formed through a reaction of gamma-polyglutamic acid and epsilon-polylysine, and a single active component is loaded in the composite shell; the single active component is one of salicylic acid, gallic acid or tea polyphenol. The invention also provides a preparation method and application of the nano drug-loaded particle. According to the nanoparticles, a unified ionic crosslinking process is adopted, and three kinds of nanoparticles with gamma-polyglutamic acid and epsilon-polylysine as composite shells and different single active ingredients loaded on inner cores are prepared respectively. The nanoparticles provided by the invention are stable in structure and good in biocompatibility, and can be used for preparing medicines with anti-aging, antibacterial and anti-inflammatory effects respectively or in combination.
Owner:TIANJIN UNIV OF SCI & TECH +1