The invention discloses a compound feed for broilers of 3 to 5 weeks and a preparation method of the compound feed. The compound feed comprises the following raw materials: corn, wheat, corn albumen powder, corn alcohol dregs, bean pulp, peanut meal, grease for the feed, mountain flour, calcium hydrogen phosphate, table salt, synthetic lysine, synthetic methionine, synthetic threonine, choline chloride, a composite vitamin premix, a composite trace element premix and liquid phytase. The preparation method comprises the following steps of: crushing; mixing uniformly, and granulating; and uniformly spraying the liquid phytase onto the surfaces of feed granules obtained by granulating. The compound feed has the advantages that: the nutritional requirements of the broilers of 3 to 5 weeks on phosphorus are met, the using amount of inorganic phosphorus raw materials in the feed is reduced, and the pollution of the phosphorus in excrement to the environment is reduced; and the enzyme activity of the phytase is kept to the maximum limit by spraying the liquid phytase onto the surfaces of the feed granules after granulation is finished.