42 results about "Streptomyces strain" patented technology

The invention discloses a marine streptomyces strain SHEa3, a compound derived from the marine streptomyces strain SHEa3 and application of the marine streptomyces strain SHEa3, the classification name of the marine streptomyces strain SHEa3 is Streptomyces sp, the preservation number of the marine streptomyces strain SHEa3 is GDMCC No: 66667, and the preservation date of the marine streptomyces strain SHEa3 is July 14, 2025. The invention also discloses a sesquiterpenoids compound streptaviol A derived from marine streptomyces and application of the sesquiterpenoids compound streptaviol A in preparation of drugs for preventing and treating vibrio diseases of mariculture animals. The invention further discloses application of the sesquiterpenoids, namely the sea threitol C, derived from the marine streptomyces in preparation of drugs for preventing and treating vibrio diseases of mariculture animals. The marine streptomyces source compound has efficient anti-vibrio activity, and the marine streptomyces source compound streptaviol A and the helithreitol C are used for preparing the medicine for preventing and treating vibrio diseases of mariculture animals, so that the side effect is low, and the activity is excellent.

The invention relates to a streptomyces sp. Strain EC15 and an application of the streptomyces sp. Strain EC15. The streptomyces strain EC15 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation address is No.3, yard 1, Beichen West Road, Chaoyang District, Beijing, the preservation date is December 25, 2024, and the preservation number is CGMCC NO.33195. The streptomyces strain EC15 has the advantages that the streptomyces strain EC15 can be used for preparing the streptomyces strain EC15; the strain has the functions of dissolving organic phosphorus, dissolving inorganic phosphorus, producing a biological membrane, producing an iron carrier, producing IAA and producing ACC deaminase. The EC15 bacterial liquid is used for soaking seeds under the stress of 200 mmol / L and 250 mmol / L NaCl, so that the germination potential, the germination rate, the germination index, the radicle length, the germ length and the fresh weight of group seedlings of the alfalfa seeds can be obviously improved. After the EC15 strain is inoculated, under the stress of 200 mmol / L NaCl, the plant height, stem diameter, leaf area and overground part fresh and dry weight of alfalfa plants can be obviously improved.

The invention discloses a strain of streptomyces rochei PBSH7 and an application of the strain of streptomyces rochei PBSH7. Belongs to the technical field of plant disease biological control. The strain for preventing and treating the potato scab, provided by the invention, is a streptomyces rochei strain PBSH7, and the preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) No.15827. When the streptomyces rochei PBSH7 is used for furrow application treatment, the control effect on the potato scab reaches 78.37%, and the growth and tuber quality of potatoes can be promoted. The compound tetremycin C is obtained by carrying out enlarged fermentation, extraction, vacuum concentration and separation and purification by a reversed-phase preparative high performance liquid chromatograph on strains, and the bacteriostatic effect of the compound tetremycin C on potato scab is 125 mu g / mL, and the bacteriostatic diameter of the compound is 22.33 mm. The streptomyces rochei PBSH7 provided by the invention is used for preventing and treating potato scab, and has good development and application prospects.

The utility model relates to the field of sample bottles, and discloses a sample bottle for streptomyces darkness strain breeding, which comprises a conical wall, the bottom of the conical wall is fixedly connected with a bottom wall, an anti-backflow component is arranged in the conical wall, a bottle cap is arranged at the top of the conical wall, and a fixing component is arranged at the bottom of the bottle cap. The backflow prevention assembly comprises a vertical wall and an extending wall, the outer wall of the vertical wall is fixedly connected to the interior of the conical wall, the inner wall of the extending wall is fixedly connected to the top of the vertical wall, and a limiting groove is formed in the top of the vertical wall. According to the utility model, the connecting part between the conical wall and the vertical wall is extended, so that the effect that a solution in the bottle cannot flow into the vertical wall during centrifugation or shaking is achieved, and the problem that the solution flows upwards into the vertical wall and is not uniformly mixed during centrifugation or shaking is solved; and the high efficiency of the sample bottle for streptomyces darkness strain breeding is improved.

The application provides a streptomyces LZZY-S3 and application thereof, and belongs to the field of microorganisms.The streptomyces LZZY-S3 provided by the application enriches strains for biological control, and realizes the dual functions of plant resistance to pathogenic bacteria and plant promotion.The streptomyces LZZY-S3 has the function of inhibiting fungi in a wide range, and can be applied to plant resistance to pathogenic bacteria, and the pathogenic bacteria include Exobasidium vexans, Botryosphaeria spp., Gibberella, Fusarium oxysporum, Pythium, Fusarium graminearum, Didymella, Fusarium pseudograminearum, Trichothecium roseum, Coniella diplodiella, Colletotrichum graminicola or Rhizoctonia cerealis, wherein the inhibition rate of Exobasidium vexans reaches 91.2%.The streptomyces LZZY-S3 can also be applied to plant promotion, preparation of nitrogen-fixing bacterial agents and preparation of ACC deaminase bacterial agents and the like.

This invention discloses an engineered Streptomyces strain that produces tacrolimus, its construction method, and its applications. The strain is *Streptomyces tsukuba* (…). Streptomyces tsukubaensis QZ001 was the starting strain, and homologous recombination technology was used to knock out the [specific component] in the starting strain. tdha Genes and tcdh Genes and overexpression tulz Genes were used to construct an engineered Streptomyces strain that produces tacrolimus: Streptomyces tsukuba ( Streptomyces tsukubaensis The invention relates to strain QZ004, and optimizes the fermentation medium for engineered Streptomyces strains. Both the Streptomyces strain and the engineered Streptomyces strain can be used for the production of tacrolimus, tacrolimus derivatives, or anti-rejection drugs. The strain provided by this invention possesses stable genetic characteristics, a simplified fermentation process, and abundant fermentation yield, making it suitable for the large-scale production of tacrolimus.

The invention provides a streptomyces bambusae strain BJSD1-1 and application thereof, and belongs to the technical field of biological control. The strain is classified and named as Streptomyces bambusae, the preservation unit is China General Microbiological Culture Collection Center (CGMCC), the preservation date is July 9, 2025, and the preservation number is CGMCC NO.35154. The streptomyces bambusae belongs to the bacteria field, actinomycetes, actinomycetes, streptomycetes, streptomycetes, streptomycetes and streptomycetes. The strain disclosed by the invention has a good effect of preventing and treating anise anthracnose and has no influence on normal growth of anise.

The application discloses a method for dynamically regulating the content of smell and taste substances in the secondary metabolism process of streptomyces, and relates to the technical field of molecular biology. The method for dynamically regulating the content of smell and taste substances in the secondary metabolism process of streptomyces disclosed by the application determines a first promoter and an sgRNA sequence capable of targeting a first target gene affecting the synthesis of a target compound according to the types of microorganisms and the target compound; a first recombinant plasmid is constructed by using a molecular cloning method; meanwhile, a second promoter for starting the synthesis of the target compound and a gene sequence capable of encoding a Cas protein losing cutting activity are determined, and the two are connected to obtain a regulation unit; the linearized enzyme cutting product after double enzyme cutting of the first recombinant plasmid is connected with the regulation unit to obtain a time-sequential dynamic inhibition recombinant plasmid, and after the recombinant plasmid is introduced into streptomyces, a streptomyces strain with reduced content of smell and taste (geosmin) substances in the secondary metabolism process is obtained.

The invention relates to the technical field of microorganisms, and particularly discloses a streptomyces rust red strain JQ021 and application thereof. The strain is preserved in the China Center for Type Culture Collection on October 9, 2025, and the preservation number of the strain is CCTCC NO: M 20252186. The strain JQ021, a culture of the strain JQ021 and a metabolic extract produced by the strain JQ021 show efficient and broad-spectrum inhibitory activity on various aquatic pathogenic vibrios, especially vibrio parahaemolyticus, vibrio alginolyticus and vibrio Ewana. The invention also relates to a microbial preparation and an antibacterial composition containing the strain or the metabolic extract, and an application of the microbial preparation and the antibacterial composition in preparation of a preparation for preventing and treating aquaculture vibriosis. The strain provides valuable microbial resources for developing safe and efficient antibiotic substitutes.

The application discloses a marine streptomyces strain SHEa3, a compound derived from the marine streptomyces strain SHEa3 and application of the compound, the taxonomic name of the marine streptomyces strain SHEa3 is Streptomyces sp, the preservation number is GDMCC No: 66667, and the preservation date is July 14, 2025. A sesquiterpene compound streptolide A derived from the marine streptomyces and application of the sesquiterpene compound streptolide A in preparation of a medicine for preventing and treating vibrio disease of mariculture animals are disclosed. Application of a sesquiterpene compound haesuthanol C derived from the marine streptomyces in preparation of the medicine for preventing and treating the vibrio disease of the mariculture animals. The compound derived from the marine streptomyces has high efficient anti-vibrio activity, the compound streptolide A and the compound haesuthanol C derived from the marine streptomyces are used in preparation of the medicine for preventing and treating the vibrio disease of the mariculture animals, side effects are low, and activity is excellent.

The invention belongs to the technical field of microbial resources and natural pigment production, and particularly relates to a streptomyces strain for producing purpurin, a streptomyces liquid and application thereof, the streptomyces strain is XS01-03Na, the preservation number is CGMCC No.35420, and the streptomyces strain is preserved in China General Microbiological Culture Collection Center on July 28, 2025. By means of sequencing, multi-site sequence comparison, phylogenetic tree construction and the like, the XS01-03Na disclosed by the invention is found to be a new strain of streptomycete; meanwhile, the XS01-03Na disclosed by the invention has the characteristic of high yield of purpurin, and the produced purpurin has excellent stability and antibacterial activity and can be applied to various fields such as printing and dyeing, food processing, medicine and health care and the like.

The present application relates to the field of microbiological technology, and specifically discloses a strain of Streptomyces rutilocolore JQ021 and its application. The strain has been preserved in the China Center for Type Culture Collection on October 9, 2025, and the preservation number is CCTCC NO: M 20252186. The strain JQ021 and its culture, metabolic extract produced therefrom all exhibit high and broad-spectrum inhibitory activity against various aquatic pathogenic Vibrio, especially Vibrio parahaemolyticus, Vibrio alginolyticus and Vibrio owensii. The present application also relates to a microbial preparation and an antibacterial composition comprising the strain or the metabolic extract, and the application thereof in preparing a preparation for preventing and treating aquatic vibrio disease. The strain provides a valuable microbial resource for developing safe and efficient antibiotic substitutes.

This invention discloses a recombinant Streptomyces strain with enhanced tetrahydropyrimidine and hydroxytetrahydropyrimidine synthesis capabilities and its applications. Using Streptomyces SCUT-1 as the starting strain, the invention utilizes the highly efficient promoter scutP1 to overexpress the genes encoding tetrahydropyrimidine and hydroxytetrahydropyrimidine synthesis. The recombinant strain exhibits significantly improved tetrahydropyrimidine and hydroxytetrahydropyrimidine synthesis capabilities and high osmotic pressure tolerance compared to the starting strain, Streptomyces SCUT-1. The degradation efficiency of the recombinant strain is also significantly enhanced, allowing direct fermentation using waste feathers, cottonseed meal, and shrimp shells as the sole carbon and nitrogen source. The yields of the highest soluble amino acids and peptides recovered are 2.15, 1.18, and 1.15 times that of the starting strain, respectively. This invention has significant implications for the high-value conversion of agricultural waste, eliminating the need for additional reducing agents and offering mild reaction conditions, which is of great value in reducing production costs and increasing yield.

The application discloses a synthetic bacterial flora capable of improving salt tolerance of alfalfa, which is composed of Pseudomonas strain EC5, Agrobacterium strain EC17, Streptomyces strain EC15, Paracoccus strain RH39, Pseudomonas strain RH6, Pseudomonas strain RH37, Sporosarcina strain RH34 and Bacillus strain RH32. The synthetic bacterial flora has the functions of dissolving organic phosphorus, dissolving inorganic phosphorus, dissolving potassium, producing siderophore, producing biofilm, producing IAA and producing ACC deaminase. Seed soaking and germination under the stress of 200 mmol / L and 250 mmol / L NaCl can obviously improve the germination potential, germination rate, germination index, radicle length, plumule length and fresh weight of the group seedling embryo of alfalfa. Under the stress of 200 mmol / L NaCl, seed soaking with the synthetic bacterial flora can significantly improve the plant height, stem diameter, leaf area and fresh and dry weight of the above-ground part of alfalfa.

The invention discloses streptomyces baldness, a fungicide, a slow-release fertilizer as well as a preparation method and application of the streptomyces baldness, the fungicide and the slow-release fertilizer, and belongs to the technical field of microorganisms. The streptomyces calvus strain GX2024L1 is obtained by being separated from soil, and the preservation number of the streptomyces calvus strain GX2024L1 is CGMCC (China General Microbiological Culture Collection Center) No. 32902. The strain and the microbial inoculum thereof can be applied to preparation of slow-release fertilizers. When the slow-release fertilizer is prepared, the silkworm excrement is pretreated and crushed to increase the surface area of the silkworm excrement, then the silkworm excrement is inoculated with the Streptomyces calvus strain GX2024L1 or a microbial inoculum thereof for controllable fermentation, macromolecules such as cellulose, hemicellulose and polysaccharide in the silkworm excrement are moderately degraded through thallus metabolism, and a porous carrier is formed and functional groups are exposed while a structural framework is maintained. The carrier adsorbs and loads urea and a urease inhibitor through hydrogen bonds and coordination, and the slow-release fertilizer is prepared through granulation and coating. The slow-release fertilizer can realize slow release and continuous release of urea within 1-8 months, nitrogen loss is effectively inhibited by using the urease inhibitor, and dual benefits of silkworm excrement recycling and crop full-cycle nutrient accurate supply are realized.

The invention discloses streptomyces parvus, a microbial agent and application of the streptomyces parvus and the microbial agent, and relates to the technical field of environmental microorganisms. A strain of streptomyces PS-15 with excellent application potential is separated from soil of the Tibet Plateau, and the strain belongs to streptomyces and deep olive streptomyces through identification. The strain has antibacterial activity, HPLC (high performance liquid chromatography) analysis of a fermentation product of the strain shows that the abundance of a main product is high, the main product is bernin amycin C, and the strain has the characteristic of high yield of bernin amycin C and is expected to be used for industrial production of bernin amycin C and preparation of antibacterial agents.

The present invention relates to a novel isolated Streptomyces strain, Streptomyces sungeiensis SD3 (Accession number DSM34917), its engineered version and their uses in producing secondary metabolites

The invention relates to the field of microorganisms, in particular to a novel streptomyces strain capable of producing volatile antibacterial substances and application of the novel streptomyces strain. The streptomyces strain AMJ-169 related to the invention is identified as a new streptomyces strain, and also has obvious inhibitory activity on strawberry anthracnose pathogen, cucumber fusarium wilt pathogen, botrytis cinerea and the like. Volatile organic compounds generated by the strain AMJ-169 have remarkable inhibitory activity on papaya colletotrichum gloeosporioides, mango colletotrichum gloeosporioides, banana colletotrichum gloeosporioides and The volatile organic compounds and the volatile compounds thereof also have inhibitory activity on a variety of plant pathogens. The levorotatory-alpha-pinene can effectively reduce the scab diameter of strawberry anthracnose on strawberry fruits, and has significant inhibitory activity on strawberry anthracnose. The new streptomyces strain and the volatile antibacterial substance generated by the streptomyces strain provide a new way for biological prevention and control of strawberry anthracnose, and have wide development space and development and application prospects.

A Streptomyces strain and the use thereof in the synthesis of phosphatidylserine. A fermentation broth produced by means of fermentation of the Streptomyces strain uses soy lecithin and L-serine as raw materials, and can simultaneously convert phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylinositol (PI), etc. in lecithin to efficiently produce phosphatidylserine (PS). The Streptomyces strain is named Streptomyces sp. LN2, and was deposited in the China General Microbiological Culture Collection Center on 01 April 2024 with a deposit number of CGMCC NO. 30230.

The invention relates to a Streptomyces rhizosphere strain 14-3, the Streptomyces rhizosphere strain 14-3 is preserved in the Guangdong Microbiological Culture Collection Center, the preservation number is GDMCC No. 63693, and the preservation date is August 3, 2023, the preservation number is CGMCC No. 63693, the preservation number is CGMCC No. 63693, the preservation number is CGMCC No. 63693, the preservation number is CGMCC No. 63693, the preservation number is CGMCC No. 63693, and the preservation number is CGMCC No. 63693, and the preservation number is CGMCC No. 63693. The streptomyces rhizosphere strain 14-3 has a strong antagonistic effect on the main pathogenic bacterium colletotrichum truncatum causing the soybean anthracnose, and the fermentation liquor of the streptomyces rhizosphere strain 14-3 can obviously inhibit the mycelial growth of the colletotrichum truncatum, completely inhibit the germination of conidia and cause the splitting decomposition of spore cells; and the obtained fermentation liquor not only has an excellent prevention and treatment effect on soybean anthracnose, but also has no influence on soybean growth.

The application discloses a kind of streptomyces youssoufiensis strain and the application of its metabolite cis-3-indoleacrylic acid, belongs to the technical field of microbial pesticides.The preservation name of streptomyces youssoufiensis strain is streptomyces youssoufiensis YMF3.862 strain, is preserved in China Microbial Culture Collection Center;Preservation date: May 20, 2024;Preservation number: CGMCC No.30698.The application has the characteristics of low cost, good effect, no residue, safety to human and environment, and the preparation of biological pesticide by YMF3.862 strain and its metabolite cis-3-indoleacrylic acid has more than 60% of the control effect on tobacco root-knot nematode disease, tobacco bacterial wilt and the composite disease caused by the two.

The invention discloses a streptomyces strain WS-15992 and an application of the streptomyces strain WS-15992. The preservation number of the streptomyces mayteni WS-15992 is CCTCC (China Center for Type Culture Collection) M: 2020348, and the preservation number of the streptomyces mayteni WS-15992 is CCTCC M: 2020348. The streptomyces WS-15992 provided by the invention has strong stress resistance, is easy to ferment in a large scale, is suitable for being prepared into a preparation product through spray drying, and has a good field control effect on pear rust.

This invention discloses a strain of Streptomyces SK-2 and its application in the control of white cone rot. The Streptomyces strain of this invention (… Streptomyces SK-2 (sp.) was isolated from the rhizosphere soil of Chinese fir soil. This biocontrol bacterium can significantly inhibit the occurrence area of ​​white cone rot disease under indoor conditions, with a prevention effect of more than 68%, and has potential development and application value.

The invention relates to a streptomyces engineering bacterium with high yield of josamycin as well as a construction method and application of the streptomyces engineering bacterium. The engineering bacterium is a high-yield strain which is obtained by taking Streptomyces nanonensis ATCC17835 as an original strain and carrying out over-expression on regulatory protein genes JosR1 and JosR2 in a genome of the Streptomyces nanonensis ATCC17835, and the engineering bacterium is named as Streptomyces nanonensis CBR18-P001 (the preservation number is CCTCC No. M 2025197). The invention further discloses a preparation method of the engineering bacterium, and a preparation method of the engineering bacterium comprises the following steps: taking the Streptomyces nanonensis ATCC17835 as the original strain, carrying out over-expression on the regulatory protein genes JosR1 and JosR2 in the genome of the engineering bacterium. The fermentation yield of the strain josamycin can reach 7000 mg / L or above, and a fermentation product contains a characteristic impurity O (the molecular formula and molecular weight are 825, the relative retention time of a high performance liquid phase is 0.95, and the mass spectrum characteristic peak m / z is 826 [M + H]) as a biomarker. The invention also provides a construction method of the strain, a fermentation production process and an identification method based on characteristic impurities.

The invention relates to the field of microorganisms, in particular to streptomyces, a microbial preparation and application thereof. The invention provides Streptomyces sp., and the preservation number of the Streptomyces sp. Is GDMCC 67625. The Streptomyces sp. Has the advantages that the preservation number of the Streptomyces sp. Is GDMCC 67625; the invention provides a novel streptomyces strain LE64, a preparation containing the strain and application of the novel streptomyces strain LE64. The bacterial strain can effectively inhibit banana fusarium wilt and greatly promote banana plant growth, and an environment-friendly microbial solution is provided for solving the problem of banana fusarium wilt.

The invention discloses streptomyces LZZY-S40 with broad-spectrum bacteriostatic activity and growth promoting effect and application thereof, and belongs to the technical field of microorganisms. The invention provides streptomyces sp. LZZY-S40 with the preservation number of CGMCC (China General Microbiological Culture Collection Center) No.30320 in order to solve the problems that in the prior art, streptomyces mostly focuses on single function research, the antibacterial spectrum is relatively narrow, and the agricultural production requirement that various diseases coexist is difficult to meet. The bacterial strain has good broad-spectrum bacteriostatic activity on plant pathogenic fungi, and the bacteriostasis rate of the bacterial strain on plant pathogenic bacteria xanthomonas semitransparent reaches 100%; a spore suspension of the strain has a remarkable promoting effect on wheat root length, bud length and wheat fresh weight; in addition, the streptomyces LZZY-S40 strain can also be applied to preparation of microbial agents for producing extracellular protease, auxin, siderophore, nitrogenase and ACC deaminase.

This invention isolated a Streptomyces strain SCA4-4 with significant cellulose degradation ability from wheat rhizosphere soil samples from the dry-hot valley of the Jinsha River in Sichuan Province. After systematic polyphasic taxonomic identification, this strain was determined to be a new species of the genus Streptomyces and was named *Streptomyces jinshaensis*. Streptomyces jinshaensis The strain SCA4-4 (sp. nov.), with accession number GDMCC No: 63008, possesses biological characteristics such as cellulose degradation and nitrogen fixation capabilities. Furthermore, it can adjust the activity of related enzymes according to different substrates, thereby achieving differentiated degradation of various crop straw materials. This provides a new pathway for the recycling of agricultural waste, reduces the use of chemical fertilizers, and mitigates negative environmental impacts, demonstrating broad application potential in agriculture and the environment.

This invention discloses a Streptomyces strain AB_3, classified as amylase-producing Streptomyces (…). Streptomyces diastatochromogenes The strain is preserved under the CCTCC No. M20252932. This invention also discloses a solid-state fermentation agent of *Streptomyces AB_3*, comprising the aforementioned *Streptomyces AB_3* strain. This invention further discloses the application of *Streptomyces AB_3* strain or the solid-state fermentation agent of *Streptomyces AB_3* in controlling soil-borne bacterial wilt and in promoting crop growth. *Streptomyces AB_3* possesses multiple functions, including disease resistance and growth promotion. This invention utilizes a novel solid-state fermentation method, significantly increasing the amount of *Streptomyces* spores and solving the problem of *Streptomyces* failing to produce spores during liquid culture.

The invention provides a streptomyces, which is named as Streptomyces sp.YGL 11-2, is registered and preserved in Guangdong Microbial Culture Collection Center, and has a preservation number of GDMCC No: 66117. The invention also provides a fermentation broth and the like of the streptomyces. The streptomyces, the fermentation liquor thereof and the like have broad-spectrum antibacterial activity, and have a good antagonistic effect on banana leaf spot blight, banana long leaf spot bacteria, and / or strawberry anthracnose bacteria, fusarium oxysporum f.sp.cubense 4 microspecies, fusarium oxysporum f.sp.cubense 1 microspecies, banana anthracnose bacteria, fusarium graminearum, mango anthracnose bacteria and the like, and the streptomyces has a good antagonistic effect on banana leaf spot blight bacteria, banana long leaf spot bacteria, and / or strawberry anthracnose bacteria, fusarium oxysporum f.sp.cubense 4 microspecies, fusarium oxysporum f.sp.cubense 1 microspecies, banana anthracnose bacteria, fusarium graminearum, mango anthracnose bacteria and the like. The bacillus amyloliquefaciens has resistance to various antibiotics, is a potential biological preparation for anthracnose diseases, diseases controlled by fusarium oxysporum and the like, has a wide development space, and has a very good development and application prospect.