58 results about "Streptomyces strain" patented technology

The invention discloses a marine streptomyces strain SHEa3, a compound derived from the marine streptomyces strain SHEa3 and application of the marine streptomyces strain SHEa3, the classification name of the marine streptomyces strain SHEa3 is Streptomyces sp, the preservation number of the marine streptomyces strain SHEa3 is GDMCC No: 66667, and the preservation date of the marine streptomyces strain SHEa3 is July 14, 2025. The invention also discloses a sesquiterpenoids compound streptaviol A derived from marine streptomyces and application of the sesquiterpenoids compound streptaviol A in preparation of drugs for preventing and treating vibrio diseases of mariculture animals. The invention further discloses application of the sesquiterpenoids, namely the sea threitol C, derived from the marine streptomyces in preparation of drugs for preventing and treating vibrio diseases of mariculture animals. The marine streptomyces source compound has efficient anti-vibrio activity, and the marine streptomyces source compound streptaviol A and the helithreitol C are used for preparing the medicine for preventing and treating vibrio diseases of mariculture animals, so that the side effect is low, and the activity is excellent.

The invention relates to the field of biocontrol of plant diseases. The invention provides a Streptomyces griseoaurantiacus strain HMQAUfx21024, the strain is preserved in the China General Microbiological Culture Collection Center on January 3, 2025, and the preservation registration number of the strain is CGMCC No. 33290. The invention further provides a preparation method of the strain HMQAUfx21024, and the strain HMQAUfx21024 has the advantages that the strain HMQAUfx21024 can be used for preparing the strain HMQAUfx21024; the invention also provides a biocontrol inoculant. The invention also provides a preparation method of the biocontrol inoculant. The invention also provides application of the strain HMQAUfx21024 or the biocontrol microbial inoculum as described above or the biocontrol microbial inoculum prepared by the preparation method as described above. The invention further provides a method for preventing and treating plant diseases. The biocontrol agent is specially developed for cucumber downy mildew and target leaf spot, due to the fact that the biocontrol agent is a biological agent, a series of problems caused by use of chemical pesticides are completely avoided, pollution-free production of greenhouse vegetables is facilitated, farmers can not use or reduce the use amount of other chemical pesticides, expenses can be saved for the farmers, and the cost is reduced. Vegetable export is facilitated, and the income of farmers can be increased.

The invention relates to a streptomyces sp. Strain EC15 and an application of the streptomyces sp. Strain EC15. The streptomyces strain EC15 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation address is No.3, yard 1, Beichen West Road, Chaoyang District, Beijing, the preservation date is December 25, 2024, and the preservation number is CGMCC NO.33195. The streptomyces strain EC15 has the advantages that the streptomyces strain EC15 can be used for preparing the streptomyces strain EC15; the strain has the functions of dissolving organic phosphorus, dissolving inorganic phosphorus, producing a biological membrane, producing an iron carrier, producing IAA and producing ACC deaminase. The EC15 bacterial liquid is used for soaking seeds under the stress of 200 mmol / L and 250 mmol / L NaCl, so that the germination potential, the germination rate, the germination index, the radicle length, the germ length and the fresh weight of group seedlings of the alfalfa seeds can be obviously improved. After the EC15 strain is inoculated, under the stress of 200 mmol / L NaCl, the plant height, stem diameter, leaf area and overground part fresh and dry weight of alfalfa plants can be obviously improved.

The invention discloses a strain of streptomyces rochei PBSH7 and an application of the strain of streptomyces rochei PBSH7. Belongs to the technical field of plant disease biological control. The strain for preventing and treating the potato scab, provided by the invention, is a streptomyces rochei strain PBSH7, and the preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) No.15827. When the streptomyces rochei PBSH7 is used for furrow application treatment, the control effect on the potato scab reaches 78.37%, and the growth and tuber quality of potatoes can be promoted. The compound tetremycin C is obtained by carrying out enlarged fermentation, extraction, vacuum concentration and separation and purification by a reversed-phase preparative high performance liquid chromatograph on strains, and the bacteriostatic effect of the compound tetremycin C on potato scab is 125 mu g / mL, and the bacteriostatic diameter of the compound is 22.33 mm. The streptomyces rochei PBSH7 provided by the invention is used for preventing and treating potato scab, and has good development and application prospects.

The utility model relates to the field of sample bottles, and discloses a sample bottle for streptomyces darkness strain breeding, which comprises a conical wall, the bottom of the conical wall is fixedly connected with a bottom wall, an anti-backflow component is arranged in the conical wall, a bottle cap is arranged at the top of the conical wall, and a fixing component is arranged at the bottom of the bottle cap. The backflow prevention assembly comprises a vertical wall and an extending wall, the outer wall of the vertical wall is fixedly connected to the interior of the conical wall, the inner wall of the extending wall is fixedly connected to the top of the vertical wall, and a limiting groove is formed in the top of the vertical wall. According to the utility model, the connecting part between the conical wall and the vertical wall is extended, so that the effect that a solution in the bottle cannot flow into the vertical wall during centrifugation or shaking is achieved, and the problem that the solution flows upwards into the vertical wall and is not uniformly mixed during centrifugation or shaking is solved; and the high efficiency of the sample bottle for streptomyces darkness strain breeding is improved.

The present invention belongs to the technical field of the application of soil microorganisms and the prevention and control of crop diseases. The present invention provides the application of Streptomyces morookaense strain SGX33 in the preparation of a microbial fertilizer for preventing and controlling plant diseases, wherein the plant diseases are wheat root rot or banana wilt. The fertilizer containing Streptomyces morookaense strain SGX33 of the present invention increases the plant height of wheat seeds in soil containing wheat root rot pathogens, and can basically reach the growth level of wheat seeds in soil without pathogens. At the same time, for fields with a banana wilt incidence rate of more than 50% in the previous year, when bananas are replanted, the prevention and control of banana wilt reaches more than 75%, and the yield increases by more than 80%.

The application provides a streptomyces LZZY-S3 and application thereof, and belongs to the field of microorganisms.The streptomyces LZZY-S3 provided by the application enriches strains for biological control, and realizes the dual functions of plant resistance to pathogenic bacteria and plant promotion.The streptomyces LZZY-S3 has the function of inhibiting fungi in a wide range, and can be applied to plant resistance to pathogenic bacteria, and the pathogenic bacteria include Exobasidium vexans, Botryosphaeria spp., Gibberella, Fusarium oxysporum, Pythium, Fusarium graminearum, Didymella, Fusarium pseudograminearum, Trichothecium roseum, Coniella diplodiella, Colletotrichum graminicola or Rhizoctonia cerealis, wherein the inhibition rate of Exobasidium vexans reaches 91.2%.The streptomyces LZZY-S3 can also be applied to plant promotion, preparation of nitrogen-fixing bacterial agents and preparation of ACC deaminase bacterial agents and the like.

This invention discloses an engineered Streptomyces strain that produces tacrolimus, its construction method, and its applications. The strain is *Streptomyces tsukuba* (…). Streptomyces tsukubaensis QZ001 was the starting strain, and homologous recombination technology was used to knock out the [specific component] in the starting strain. tdha Genes and tcdh Genes and overexpression tulz Genes were used to construct an engineered Streptomyces strain that produces tacrolimus: Streptomyces tsukuba ( Streptomyces tsukubaensis The invention relates to strain QZ004, and optimizes the fermentation medium for engineered Streptomyces strains. Both the Streptomyces strain and the engineered Streptomyces strain can be used for the production of tacrolimus, tacrolimus derivatives, or anti-rejection drugs. The strain provided by this invention possesses stable genetic characteristics, a simplified fermentation process, and abundant fermentation yield, making it suitable for the large-scale production of tacrolimus.

The invention discloses a streptomyces strain S1 for preventing and controlling root rot, the streptomyces strain S1 is classified and named as Streptomyces peuceius, the Streptomyces peuceius is preserved in China General Microbiological Culture Collection Center on April 26, 2024, and the preservation number of the strain is CGMCC NO.30458. The invention further discloses a preparation method of the Streptomyces peuceius strain S1 for preventing and controlling root rot. The invention also discloses the application of the streptomyces strain S1 or the combined use of the streptomyces strain S1 and resource substances in prevention and control of root rot, and the resource substances are selected from at least one of methyl jasmonate and brassinolide.

The invention discloses a streptomyces strain for preventing and treating sugarcane pokkah boeng rot, which is streptomyces noursei NN-Q01-01 with the preservation number of CGMCC (China General Microbiological Culture Collection Center) No.28993, and application of fermentation liquor of the streptomyces strain in the aspect of preventing and treating the sugarcane pokkah boeng rot. The streptomyces for preventing and treating the sugarcane pokkah boeng rot is separated from healthy passion fruit rhizosphere soil, has an antagonistic effect on the sugarcane pokkah boeng rot and can effectively prevent and treat the sugarcane pokkah boeng rot.

The invention provides a streptomyces bambusae strain BJSD1-1 and application thereof, and belongs to the technical field of biological control. The strain is classified and named as Streptomyces bambusae, the preservation unit is China General Microbiological Culture Collection Center (CGMCC), the preservation date is July 9, 2025, and the preservation number is CGMCC NO.35154. The streptomyces bambusae belongs to the bacteria field, actinomycetes, actinomycetes, streptomycetes, streptomycetes, streptomycetes and streptomycetes. The strain disclosed by the invention has a good effect of preventing and treating anise anthracnose and has no influence on normal growth of anise.

The application discloses a method for dynamically regulating the content of smell and taste substances in the secondary metabolism process of streptomyces, and relates to the technical field of molecular biology. The method for dynamically regulating the content of smell and taste substances in the secondary metabolism process of streptomyces disclosed by the application determines a first promoter and an sgRNA sequence capable of targeting a first target gene affecting the synthesis of a target compound according to the types of microorganisms and the target compound; a first recombinant plasmid is constructed by using a molecular cloning method; meanwhile, a second promoter for starting the synthesis of the target compound and a gene sequence capable of encoding a Cas protein losing cutting activity are determined, and the two are connected to obtain a regulation unit; the linearized enzyme cutting product after double enzyme cutting of the first recombinant plasmid is connected with the regulation unit to obtain a time-sequential dynamic inhibition recombinant plasmid, and after the recombinant plasmid is introduced into streptomyces, a streptomyces strain with reduced content of smell and taste (geosmin) substances in the secondary metabolism process is obtained.

The present invention discloses a potassium-dissolving Streptomyces with high efficiency and its uses. The potassium-dissolving Streptomyces with high efficiency is identified as Streptomyces wuyuanensis ( Streptomyces wuyuanensis ), and the strain name is KLBMP9348, which is deposited in the Guangdong Microbial Culture Collection Center. The deposition date is August 24, 2022, and the deposition number is GDMCC NO: 62737. Compared with the prior art, the potassium-dissolving Streptomyces with high efficiency KLBMP9348 provided by the present invention has good growth characteristics and is easy to culture. It is a multifunctional strain with high potassium-dissolving activity, and also has the characteristics of phosphorus solubilization, plant hormone production and inhibition of plant black spot disease. Therefore, it can be used to prepare products for potassium dissolution, phosphorus solubilization, plant hormone production and inhibition of plant black spot disease, such as microbial fertilizers, etc. It has good comprehensive performance and has good application prospects and market value.

The invention relates to the technical field of microorganisms, and particularly discloses a streptomyces rust red strain JQ021 and application thereof. The strain is preserved in the China Center for Type Culture Collection on October 9, 2025, and the preservation number of the strain is CCTCC NO: M 20252186. The strain JQ021, a culture of the strain JQ021 and a metabolic extract produced by the strain JQ021 show efficient and broad-spectrum inhibitory activity on various aquatic pathogenic vibrios, especially vibrio parahaemolyticus, vibrio alginolyticus and vibrio Ewana. The invention also relates to a microbial preparation and an antibacterial composition containing the strain or the metabolic extract, and an application of the microbial preparation and the antibacterial composition in preparation of a preparation for preventing and treating aquaculture vibriosis. The strain provides valuable microbial resources for developing safe and efficient antibiotic substitutes.

The application discloses a kind of Streptomyces calvus, bacterial agent, slow-release fertilizer and its preparation method and application, belong to microbial technical field.Streptomyces calvus Strain GX2024L1 is isolated from soil, and the preservation number is CGMCC No.32902.The strain and its bacterial agent can be used for preparing slow-release fertilizer.When preparing slow-release fertilizer, silkworm sand is pretreated first, and the surface area of silkworm sand is increased by crushing, then Streptomyces calvus Strain GX2024L1 or its bacterial agent is inoculated for controlled fermentation, and the cellulose, hemicellulose and polysaccharide in silkworm sand are moderately degraded by microbial metabolism, so as to form a porous carrier and expose functional groups while maintaining the structural skeleton.The carrier is used to adsorb and load urea and urease inhibitor through hydrogen bonding and coordination, and slow-release fertilizer is prepared by granulation and coating.The slow-release fertilizer can realize slow release and continuous release of urea within 1-8 months, effectively inhibit nitrogen loss by using urease inhibitor, realize the dual benefits of silkworm sand resource utilization and precise supply of nutrients in the whole cycle of crops.

The application discloses a marine streptomyces strain SHEa3, a compound derived from the marine streptomyces strain SHEa3 and application of the compound, the taxonomic name of the marine streptomyces strain SHEa3 is Streptomyces sp, the preservation number is GDMCC No: 66667, and the preservation date is July 14, 2025. A sesquiterpene compound streptolide A derived from the marine streptomyces and application of the sesquiterpene compound streptolide A in preparation of a medicine for preventing and treating vibrio disease of mariculture animals are disclosed. Application of a sesquiterpene compound haesuthanol C derived from the marine streptomyces in preparation of the medicine for preventing and treating the vibrio disease of the mariculture animals. The compound derived from the marine streptomyces has high efficient anti-vibrio activity, the compound streptolide A and the compound haesuthanol C derived from the marine streptomyces are used in preparation of the medicine for preventing and treating the vibrio disease of the mariculture animals, side effects are low, and activity is excellent.

The invention belongs to the technical field of microbial resources and natural pigment production, and particularly relates to a streptomyces strain for producing purpurin, a streptomyces liquid and application thereof, the streptomyces strain is XS01-03Na, the preservation number is CGMCC No.35420, and the streptomyces strain is preserved in China General Microbiological Culture Collection Center on July 28, 2025. By means of sequencing, multi-site sequence comparison, phylogenetic tree construction and the like, the XS01-03Na disclosed by the invention is found to be a new strain of streptomycete; meanwhile, the XS01-03Na disclosed by the invention has the characteristic of high yield of purpurin, and the produced purpurin has excellent stability and antibacterial activity and can be applied to various fields such as printing and dyeing, food processing, medicine and health care and the like.

The present application relates to the field of microbiological technology, and specifically discloses a strain of Streptomyces rutilocolore JQ021 and its application. The strain has been preserved in the China Center for Type Culture Collection on October 9, 2025, and the preservation number is CCTCC NO: M 20252186. The strain JQ021 and its culture, metabolic extract produced therefrom all exhibit high and broad-spectrum inhibitory activity against various aquatic pathogenic Vibrio, especially Vibrio parahaemolyticus, Vibrio alginolyticus and Vibrio owensii. The present application also relates to a microbial preparation and an antibacterial composition comprising the strain or the metabolic extract, and the application thereof in preparing a preparation for preventing and treating aquatic vibrio disease. The strain provides a valuable microbial resource for developing safe and efficient antibiotic substitutes.

This invention discloses a recombinant Streptomyces strain with enhanced tetrahydropyrimidine and hydroxytetrahydropyrimidine synthesis capabilities and its applications. Using Streptomyces SCUT-1 as the starting strain, the invention utilizes the highly efficient promoter scutP1 to overexpress the genes encoding tetrahydropyrimidine and hydroxytetrahydropyrimidine synthesis. The recombinant strain exhibits significantly improved tetrahydropyrimidine and hydroxytetrahydropyrimidine synthesis capabilities and high osmotic pressure tolerance compared to the starting strain, Streptomyces SCUT-1. The degradation efficiency of the recombinant strain is also significantly enhanced, allowing direct fermentation using waste feathers, cottonseed meal, and shrimp shells as the sole carbon and nitrogen source. The yields of the highest soluble amino acids and peptides recovered are 2.15, 1.18, and 1.15 times that of the starting strain, respectively. This invention has significant implications for the high-value conversion of agricultural waste, eliminating the need for additional reducing agents and offering mild reaction conditions, which is of great value in reducing production costs and increasing yield.

The application discloses a synthetic bacterial flora capable of improving salt tolerance of alfalfa, which is composed of Pseudomonas strain EC5, Agrobacterium strain EC17, Streptomyces strain EC15, Paracoccus strain RH39, Pseudomonas strain RH6, Pseudomonas strain RH37, Sporosarcina strain RH34 and Bacillus strain RH32. The synthetic bacterial flora has the functions of dissolving organic phosphorus, dissolving inorganic phosphorus, dissolving potassium, producing siderophore, producing biofilm, producing IAA and producing ACC deaminase. Seed soaking and germination under the stress of 200 mmol / L and 250 mmol / L NaCl can obviously improve the germination potential, germination rate, germination index, radicle length, plumule length and fresh weight of the group seedling embryo of alfalfa. Under the stress of 200 mmol / L NaCl, seed soaking with the synthetic bacterial flora can significantly improve the plant height, stem diameter, leaf area and fresh and dry weight of the above-ground part of alfalfa.

The invention discloses streptomyces baldness, a fungicide, a slow-release fertilizer as well as a preparation method and application of the streptomyces baldness, the fungicide and the slow-release fertilizer, and belongs to the technical field of microorganisms. The streptomyces calvus strain GX2024L1 is obtained by being separated from soil, and the preservation number of the streptomyces calvus strain GX2024L1 is CGMCC (China General Microbiological Culture Collection Center) No. 32902. The strain and the microbial inoculum thereof can be applied to preparation of slow-release fertilizers. When the slow-release fertilizer is prepared, the silkworm excrement is pretreated and crushed to increase the surface area of the silkworm excrement, then the silkworm excrement is inoculated with the Streptomyces calvus strain GX2024L1 or a microbial inoculum thereof for controllable fermentation, macromolecules such as cellulose, hemicellulose and polysaccharide in the silkworm excrement are moderately degraded through thallus metabolism, and a porous carrier is formed and functional groups are exposed while a structural framework is maintained. The carrier adsorbs and loads urea and a urease inhibitor through hydrogen bonds and coordination, and the slow-release fertilizer is prepared through granulation and coating. The slow-release fertilizer can realize slow release and continuous release of urea within 1-8 months, nitrogen loss is effectively inhibited by using the urease inhibitor, and dual benefits of silkworm excrement recycling and crop full-cycle nutrient accurate supply are realized.

The invention discloses streptomyces parvus, a microbial agent and application of the streptomyces parvus and the microbial agent, and relates to the technical field of environmental microorganisms. A strain of streptomyces PS-15 with excellent application potential is separated from soil of the Tibet Plateau, and the strain belongs to streptomyces and deep olive streptomyces through identification. The strain has antibacterial activity, HPLC (high performance liquid chromatography) analysis of a fermentation product of the strain shows that the abundance of a main product is high, the main product is bernin amycin C, and the strain has the characteristic of high yield of bernin amycin C and is expected to be used for industrial production of bernin amycin C and preparation of antibacterial agents.

The present invention relates to a novel isolated Streptomyces strain, Streptomyces sungeiensis SD3 (Accession number DSM34917), its engineered version and their uses in producing secondary metabolites

The invention relates to the field of microorganisms, in particular to a novel streptomyces strain capable of producing volatile antibacterial substances and application of the novel streptomyces strain. The streptomyces strain AMJ-169 related to the invention is identified as a new streptomyces strain, and also has obvious inhibitory activity on strawberry anthracnose pathogen, cucumber fusarium wilt pathogen, botrytis cinerea and the like. Volatile organic compounds generated by the strain AMJ-169 have remarkable inhibitory activity on papaya colletotrichum gloeosporioides, mango colletotrichum gloeosporioides, banana colletotrichum gloeosporioides and The volatile organic compounds and the volatile compounds thereof also have inhibitory activity on a variety of plant pathogens. The levorotatory-alpha-pinene can effectively reduce the scab diameter of strawberry anthracnose on strawberry fruits, and has significant inhibitory activity on strawberry anthracnose. The new streptomyces strain and the volatile antibacterial substance generated by the streptomyces strain provide a new way for biological prevention and control of strawberry anthracnose, and have wide development space and development and application prospects.

A Streptomyces strain and the use thereof in the synthesis of phosphatidylserine. A fermentation broth produced by means of fermentation of the Streptomyces strain uses soy lecithin and L-serine as raw materials, and can simultaneously convert phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylinositol (PI), etc. in lecithin to efficiently produce phosphatidylserine (PS). The Streptomyces strain is named Streptomyces sp. LN2, and was deposited in the China General Microbiological Culture Collection Center on 01 April 2024 with a deposit number of CGMCC NO. 30230.

The invention relates to a Streptomyces rhizosphere strain 14-3, the Streptomyces rhizosphere strain 14-3 is preserved in the Guangdong Microbiological Culture Collection Center, the preservation number is GDMCC No. 63693, and the preservation date is August 3, 2023, the preservation number is CGMCC No. 63693, the preservation number is CGMCC No. 63693, the preservation number is CGMCC No. 63693, the preservation number is CGMCC No. 63693, the preservation number is CGMCC No. 63693, and the preservation number is CGMCC No. 63693, and the preservation number is CGMCC No. 63693. The streptomyces rhizosphere strain 14-3 has a strong antagonistic effect on the main pathogenic bacterium colletotrichum truncatum causing the soybean anthracnose, and the fermentation liquor of the streptomyces rhizosphere strain 14-3 can obviously inhibit the mycelial growth of the colletotrichum truncatum, completely inhibit the germination of conidia and cause the splitting decomposition of spore cells; and the obtained fermentation liquor not only has an excellent prevention and treatment effect on soybean anthracnose, but also has no influence on soybean growth.

The application discloses a kind of streptomyces youssoufiensis strain and the application of its metabolite cis-3-indoleacrylic acid, belongs to the technical field of microbial pesticides.The preservation name of streptomyces youssoufiensis strain is streptomyces youssoufiensis YMF3.862 strain, is preserved in China Microbial Culture Collection Center;Preservation date: May 20, 2024;Preservation number: CGMCC No.30698.The application has the characteristics of low cost, good effect, no residue, safety to human and environment, and the preparation of biological pesticide by YMF3.862 strain and its metabolite cis-3-indoleacrylic acid has more than 60% of the control effect on tobacco root-knot nematode disease, tobacco bacterial wilt and the composite disease caused by the two.

The present invention belongs to the field of microbial technology, and specifically discloses a strain of Streptomyces sp. B4503 and its application in controlling banana wilt. The strain of Streptomyces sp. B4503 was deposited at the China Center for Type Culture Collection (CCTCC) on August 19, 2019, and the deposit number is CCTCC NO: M 2019647. In the present invention, the secondary metabolites produced by the strain of Streptomyces sp. B4503 have a significant inhibitory effect on the pathogenic fungus of banana wilt, physiological race 4 (Foc TR4), can inhibit the mycelial growth of Foc TR4, and change the typical growth morphology of the mycelium. The strain of Streptomyces sp. B4503 can be applied to control banana wilt and has the development and application value of a biological control agent.

The invention discloses an engineering streptomycete strain for producing neohypericin and a construction method of the engineering streptomycete strain, the engineering streptomycete strain is obtained by modifying a neohypericin biosynthetic gene cluster from streptomyces spectaculum CGMCC (China General Microbiological Culture Collection Center) 4.6311, and integrating the modified neohypericin biosynthetic gene cluster and a selection marker gene into a genome of streptomyces albus J1074, and the engineering streptomycete strain is obtained by constructing the engineering streptomycete strain. The average shake flask fermentation level can reach 153 mg / L. And the method has wide application value for heterologous expression and industrial production of the neomeicin.