The invention provides a carbon disulfide fumigation compound agent for killing insects, bacteria and nematode, which is formed by combining carbon disulfide fumigation insecticide and a fumigation medicament with the function of killing insects, bacteria and nematode. The compound agent is characterized in that the compound agent consists of the carbon disulfide fumigation insecticide, chloropicrin, o-dichlorobenzene, sulfuryl fluoride, sulfuryl chloride, chlorine gas, carbon dioxide or nitrogen as inert gas; two components are combined into the carbon disulfide fumigation compound agent for killing insects, bacteria and nematode according to weight portion; three components are combined into the carbon disulfide fumigation compound agent for killing insects, bacteria and nematode according to weight portion; four components are combined into the carbon disulfide fumigation compound agent for killing insects, bacteria and nematode according to weight portion; and five components are combined into the carbon disulfide fumigation compound agent for killing insects, bacteria and nematode according to weight portion. The combination implementing proposal of the invention performs compounding according to the fumigation and pest removal of plant quarantine, health quarantine, logs, containers, soil, commodity maintenance, scrapped vessels, animal-plane specimen museums and the like, and has great social benefit and economic benefit.