The invention relates to a biological pesticide composition. The biological pesticide composition comprises an A component, a B component and a C component. The A component comprises camphor, rheum officinale, chili and accessories. The B component comprises matrine, nicotiana alkaloids, aconitine, lavender essential oil, patchouli oil and perilla leaf oil. The C component comprises rhizoma atractylodes, poria cocos, dried pinellia, dried orange peel and dahurian angelica root. The weight ratio of the A component, the B component and the C component is 1:1.2-2:2.5-3. The combination of the plurality of components has a synergistic effect. The composition belongs to an insecticidal acaricidal bactericidal pesticide, and can be used for disease and pest control for vegetables, fruit trees, flowers, and the like. The composition is free of phytotoxicity for crops, free of residue, free of pollution to the environment and agricultural products, capable of not killing natural enemies, free of hazards causing abnormality, cancer and mutation for mammals, high in pest killing effects, efficient, safe and good in control effects.