141results about How to "Good killing effect" patented technology

The invention relates to the technical field of fibers, and discloses an ultrahigh-moisture-absorption anti-static polyester fiber and a preparation method thereof. The preparation method comprises the following steps: carrying out nucleophilic substitution reaction on 1, 2-benzisothiazolin-3-one and methacryloyl chloride to obtain modified benzisothiazolinone; the preparation method comprises the following steps: carrying out nucleophilic substitution reaction on phosphonitrilic chloride trimer and allylamine, and then carrying out nucleophilic substitution reaction on the phosphonitrilic chloride trimer and melamine again to obtain modified cyclophosphazene; the preparation method comprises the following steps: mixing gamma-methacryloxypropyltrimethoxysilane with aluminum zinc oxide for reaction, and mixing the obtained modified aluminum zinc oxide with modified benzisothiazolinone and modified cyclophosphazene for copolymerization in the presence of an initiator to obtain a flame-retardant antibacterial additive; mixing the flame-retardant antibacterial additive, calcium carbonate and polyethylene glycol terephthalate, performing melt spinning, and performing acid treatment to obtain modified polyester fibers; dipping the modified polyester fiber in a finishing liquid containing modified chitosan to obtain the ultrahigh-moisture-absorption anti-static polyester fiber.

The invention discloses an antibacterial peptide and application thereof. The amino acid sequence of the antibacterial peptide disclosed by the invention is KKKEHRLLHRVLFHRL. The minimum inhibitory concentration of the antibacterial peptide to staphylococcus aureus is 4.5 mu g / mL, and the minimum bactericidal concentration of the antibacterial peptide to staphylococcus aureus is 72.7 mu g / mL. The antibacterial peptide disclosed by the invention has remarkable antibacterial activity on staphylococcus aureus and is expected to be widely applied as a novel bacteriostatic agent for preventing and treating staphylococcus aureus.

The invention discloses a serum-free culture system and culture method of NK cells. The invention firstly discloses a serum-free culture system of the NK cells, wherein the serum-free culture system comprises a coating solution, an amplification culture medium, an activation culture medium and autologous plasma; the invention further discloses a culture method for NK cells by using the serum-free culture system. The method for culturing the NK cells by using the serum-free culture system disclosed by the invention reduces the culture cost of the NK cells, can simply, quickly, efficiently and safely obtain a large number of NK cells with high activity, high purity and strong killing ability in vitro, provides a better cell source for clinical application of the NK cells, and promotes further development of an NK cell treatment technology.

The invention provides a polyvinylidene fluoride-based nanofiber yarn wave-absorbing fabric as well as a preparation method and application thereof, and belongs to the technical field of preparation of wave-absorbing composite materials. The preparation method comprises the following steps: preparing nanofiber yarns or nanofiber core-spun yarns by adopting a conjugate electrostatic spinning technology, directly adding a conductive substance into a spinning solution to form conductive nanofibers, and further coating the nanofiber yarns or the nanofiber core-spun yarns with a PDA shell layer to improve the wear resistance and reduce silver nanoparticles in situ; finally, the yarns are woven into fabric through a weaving or knitting technology, and the fabric is applied to the fields of buildings, electromagnetic protective clothing, flexible electronics and the like. Compared with an existing microwave absorbing material, the fabric-based material is light in weight and good in mechanical flexibility and processability. Fabrics formed of nanofiber yarns or nanofiber core spun yarns facilitate the induction of interfacial polarization and multiple reflections, and can deeply design material properties. The material provided by the invention has better wear resistance, wearability and microwave absorption performance, and is suitable for actual production and application.

The invention discloses an NK cell culture system and an in-vitro amplification method. The invention firstly discloses a culture system of the NK cells, wherein the culture system comprises a coating solution, an activation culture medium and an amplification culture medium. The invention further discloses a method for in-vitro amplification of NK cells by using the culture system. According to the method for amplifying the NK cells in vitro, the use of protein cell factors is simplified, only two factors of IL-2 and IL-15 are matched with CD16 and progesterone to directly culture mononuclear cells, and the required cost can be reduced to a great extent; sorting is not needed, all mononuclear cells can be used for culture, the operation procedure is simplified, and the culture cost is reduced; the process is simplified, and pollution is avoided to the greatest extent; meanwhile, the cultured NK cells are stable, safe, high in activity, enhanced in expansion, high in purity, short in period, strong in killing ability, high in cost performance and suitable for industrial production.

The invention relates to the field of new materials, and discloses an antifouling and antibacterial coating material as well as a preparation method and application thereof, and the antifouling and antibacterial coating material comprises glycidyl methacrylate, a methacrylate betaine monomer and a methacrylate quaternary ammonium salt monomer. Compared with a release type antifouling and antibacterial coating, the antifouling and antibacterial coating material adopts a bionic technology, uses sulphobetaine as a functional group, is good in biocompatibility, does not contain toxic or heavy metal antibacterial agents, can ensure that the material is non-toxic for a long time, realizes eco-friendly long-acting antifouling and antibacterial effects, can be combined with a large number of water molecules, and has the advantages of being environmentally friendly and free of pollution. The coating contains quaternary ammonium salt monomers, forms a hydration layer on the surface, keeps certain biological inertness, reduces protein adsorption, contains the quaternary ammonium salt monomers, has excellent inhibition and killing effects on various bacterial infections, overcomes the problem that the coating is easy to fall off, and realizes firm bonding of the surface of the pipeline.

The invention provides an anti-FAP nano antibody. The anti-FAP nano antibody comprises a complementary determining region (CDR) and a framework region (FR), wherein the complementarity determining region CDR comprises complementarity determining regions CDR1-CDR3, and the complementarity determining regions CDR1-CDR3 are And the framework area FR comprises framework areas FR1-FR28. According to the invention, an alpaca phage antibody library immunized by human FAP extracellular domain protein is successfully constructed, seven new anti-FAP nano antibody VHH sequences are screened from the alpaca phage antibody library, and the nano antibody sequences not only can recognize human FAP antigens, but also can recognize mouse FAP antigens. Meanwhile, the nano antibody sequence can be prepared into chimeric antigen receptor T cells (CAR-T) and can effectively kill cells highly expressing human or mouse FAP, so that the nano antibody sequence has an immunotherapy prospect of being applied to targeted FAP positive cells including tumor and fibrosis diseases.

The invention discloses an ozone catalyst and a preparation method and application thereof, Ni (NO3) 26H2O and Al (NO3) 29H2O are used as raw materials, and NiAl-LDH is prepared through a coprecipitation method; the preparation method comprises the following steps: preparing NiAl-LDH, reacting NiAl-LDH, AgNO3 and a Na2HPO4 solution to prepare Ag3PO4, and finally compounding NiAl-LDH and Ag3PO4 to prepare the ozone catalyst Ag3PO4 / NiAl-LDH composite material. The Ag3PO4 / NiAl-LDH composite material is used as an ozone catalyst to be applied to algae removal through combination of catalytic ozonation and a quorum sensing inhibitor, so that cell walls and internal structures of algae are more efficiently destroyed, and the algae removal effect is improved.

The present application relates to the technical field of nematicides for pine wood nematode disease, and specifically discloses a highly efficient compound nematicide for pine wood nematode disease and a preparation method thereof. The components of the compound nematicide include nematicides and adjuvants, the adjuvants include synergists, surfactants, solvents and rejuvenation agents, the nematicide is a mixture of emamectin benzoate and rudol, the synergist is piperonyl butoxide, the solvent includes DMF and chloride solution, and the rejuvenation agent includes amino oligosaccharide aqueous solution; in the compound nematicide, the mass fraction of rudol is 10-20%, the mass fraction of emamectin benzoate is 0.5-3.5%, and the mass fraction of the rejuvenation agent is 2-8%. The compound nematicide of the present application can also have a significant killing effect on nematodes that have developed emamectin benzoate resistance, and the selection of rejuvenation agents reduces the nematode's gnawing on pine trees, promotes the repair of internal damage to pine trees, and fully realizes the treatment of pine trees infected with pine wood nematode disease.

The invention belongs to the technical field of biology, and discloses an anti-human AXL antibody, a gene and application of the anti-human AXL antibody, and amino acid sequences of a heavy chain variable region and a light chain variable region of the anti-human AXL antibody are respectively shown as SEQ ID NO: 23-34. The anti-human AXL antibodies in some examples have the binding capacity EC50 value smaller than 2 nM for AXL antigens and have no binding capacity for irrelevant antigens Her2 and BSA, and it is indicated that the screened targeted AXL antibodies have high specificity and high binding activity. Different AXL / CD3 bispecific antibodies prepared on the basis of the anti-human AXL antibody have relatively strong killing ability (IC50: 0.1-0.5 nM) on AXL positive MDA-MB-231 cells, and have very low killing ability on AXL negative SKBR3 cells, so that off-target toxicity of the different AXL / CD3 antibodies is avoided, and the application of the different AXL / CD3 bispecific antibodies is further widened.

The invention discloses an adriamycin-tetravalent platinum drug-norcantharidin three-drug combined nano-drug as well as a preparation method and application thereof, and belongs to the technical field of medical materials. A tetravalent platinum drug modified by demethylated cantharidin and adriamycin are used as raw materials, a novel nano-drug is constructed through Cu < 2 + > coordination, and then the nano-drug combining adriamycin, the tetravalent platinum drug and demethylated cantharidin is prepared by polymerizing polydopamine with a mild photo-thermal effect. The polymer has the capacity of controllably releasing drugs under acidity and reduction, can realize photo-thermal conversion under laser irradiation to generate a mild photo-thermal effect, has a better tumor cell killing effect, has the capacity of consuming glutathione and generating hydroxyl radicals, can enter cancer cells in an endocytosis mode and release DOX, and can be used for killing tumor cells. And a new thought is provided for multi-drug combination and chemotherapy-chemokinetics therapy-photothermal therapy multi-mode combined therapy.

The invention relates to an isoxazoline derivative as well as a preparation method and application thereof, and belongs to the technical field of medicine synthesis. Specifically, the invention discloses an isoxazoline derivative as shown in a general formula (I), a pharmaceutical composition containing the derivative and application of the isoxazoline derivative and the pharmaceutical composition in preparation of anti-parasitic drugs. The structural general formula (I) of the isoxazoline derivative is # imgabs0. The isoxazoline derivative disclosed by the invention has a remarkable effect in the aspects of resisting parasites, vector insects, agricultural and forestry pests and the like, and has a wide application prospect.

The utility model provides a tea leaf fixation device for green tea production, and relates to the field of tea leaf fixation devices, the tea leaf fixation device for green tea production comprises a rotating device, the rotating end of the rotating device is provided with a placing rack, the placing rack is rotatably connected with a fixation cylinder, and one side of the placing rack is fixedly provided with a driving device; a stirring device used for tea leaf fixation is installed on the fixation cylinder, an inclined block is fixedly installed on one side of the bottom of the fixation cylinder, a sliding groove is formed in the bottom of the inclined block, the top end of the driving device is arranged in the sliding groove, and the driving device drives the fixation cylinder to swing back and forth through the inclined block. According to the tea leaf fixation device for green tea production, provided by the utility model, tea leaves in the fixation barrel move in various directions through the driving device, the inclined block and the stirring device, so that the fixation effect of the tea leaves is accelerated to a certain extent.

The utility model provides an ultraviolet sterilization device and a reverse osmosis system, and relates to the technical field of sterilization equipment, the ultraviolet sterilization device comprises a shell and an ultraviolet generation unit, the shell comprises an overflowing cavity, a water inlet and a water outlet; the ultraviolet generating unit is arranged in the overflowing cavity, the ultraviolet generating unit comprises a lamp panel and a plurality of ultraviolet lamp beads, and the wavelength of at least one ultraviolet lamp bead is different from that of other ultraviolet lamp beads. According to the utility model, the ultraviolet lamp beads with different wavelengths are configured to generate ultraviolet rays with one wavelength or ultraviolet rays with different wavelengths, and the ultraviolet radiation of the ultraviolet rays with different wavelengths can effectively destroy chemical bonds of organic matters and cellular structures of microorganisms; therefore, microorganisms, bacteria, viruses or organic matters and the like in the sewage can be efficiently removed, the problem of membrane pollution and blockage caused by microorganism breeding in the subsequent reverse osmosis process is effectively solved, the service life of the reverse osmosis device is prolonged, and the cleaning difficulty of the subsequent reverse osmosis device is also reduced.

An antibody that can specifically bind to semenogelin-1 (SEMG1) and semenogelin-2 (SEMG2) and regulate the binding of said proteins with a receptor (LILRB2, LILRB4, CD27, or TIGIT) thereof. It is proven that SEMG1 and SEMG2 have a regulating effect on immune cells, and it is proven that the antibody has a neutralizing effect. A specific linear epitope located on SEMG1 and SEMG2 proteins is provided, and it is proven that an antibody recognizing said epitope has a stronger neutralizing function, can more effectively remove an immunosuppressive effect mediated by SEMG1 and SEMG2, and promotes immune cells to inhibit and kill tumor cells. Further provided are preparation and identification methods for the antibody as well as a biomarker for the administration of such antibody. The present invention has good application prospects in the aspect of preparation of an anti-tumor drug.

The present invention provides a production method of high-quality room-temperature cooked stinky mandarin fish, including thawing, washing and cutting, soaking and sterilizing, removing odor and locking freshness, low-temperature air drying, deep-frying and shaping, sterilization and other processing of fermented stinky mandarin fish to obtain a room-temperature cooked stinky mandarin fish product. Compared with the traditional method, the present invention adopts a method of soaking and sterilizing combined with mild heat treatment sterilization to kill microorganisms, prolong the shelf life of cooked stinky mandarin fish, and can be stored at room temperature for 9 months, and significantly improve its processing quality, such as the volume shrinkage ratio of fish meat is reduced by 14.73% and the elasticity is increased by 80.24%. The present invention also innovates the formula and process for removing odor and locking freshness during the processing process. The added deodorizing and locking freshness ingredients have multiple functions such as removing odor, locking freshness and anti-oxidation, such as the product moisture content and water holding capacity are increased by 9.32% and 17.84% respectively; and improves the safety quality of cooked stinky mandarin fish during storage, such as the thiobarbituric acid content in the fifth month under 30°C storage conditions is significantly reduced by 43.39%.

The utility model discloses a sterilization device combining ultraviolet rays with copper dioxide. The sterilization device comprises a sterilization tank, a mixing box, a feeding box and a filtering box, a plurality of feeding pipes are communicated with the top of the mixing box, a first electromagnetic valve is communicated with the surface of the mixing box, a liquid pumping pipe is communicated with the surface of the first electromagnetic valve, a flow meter is mounted on the surface of the liquid pumping pipe, one end of the liquid pumping pipe is communicated with a first conveying pump, and the liquid outlet end of the first conveying pump is communicated with the upper part of the surface of the sterilization tank through a pipeline; an ultraviolet lamp is fixed to the top of the inner wall of the sterilization tank, the bottom of the sterilization tank is communicated with a residue discharging valve, the surface of the sterilization tank is communicated with a second electromagnetic valve, and the surface of the second electromagnetic valve is communicated with a second conveying pump through a pipeline. The sewage treatment device has the advantages that sewage can be sterilized more comprehensively in a mode of matching ultraviolet irradiation with a solvent after copper dioxide is mixed, and the problem that a traditional ultraviolet sterilization treatment device is poor in effect of killing microorganisms in the sewage is solved.

The utility model discloses an anti-bacteria anti-mite children towel which comprises an upper layer, an adhesive layer, an anti-bacteria anti-mite layer, a spandex stretch yarn layer and a lower layer, the upper layer, the anti-bacteria anti-mite layer, the spandex stretch yarn layer and the lower layer are connected in a bonding mode through the adhesive layer, the upper layer is arranged on one side of the anti-bacteria anti-mite layer, and the lower layer is arranged on the other side of the anti-bacteria anti-mite layer. A spandex stretch yarn layer is arranged on the side, away from the upper layer, of the antibacterial and anti-mite layer, a lower layer is arranged on the side, away from the antibacterial and anti-mite layer, of the spandex stretch yarn layer, capillary blocks are arranged on the upper end face of the upper layer, capillary grooves are formed in the upper end and the lower end of the antibacterial and anti-mite layer in a digging mode, and a plurality of sets of grooves are formed in the two sides of the capillary blocks and the inner walls of the capillary grooves in a digging mode. According to the antibacterial and anti-mite towel for children, dirt on the skin is adsorbed and removed through capillary blocks in the upper layer and capillary grooves in the antibacterial and anti-mite layer, breeding of mites can be effectively prevented through an electrostatic filtering film and a nano-silver coating in the antibacterial and anti-mite layer, meanwhile, stains are prevented from generating a chemical reaction on the towel, and breeding of bacteria and mites is avoided.

This invention discloses a portable low-temperature plasma device based on a Laval nozzle structure and its application, belonging to the field of plasma technology application technology. Specifically, it includes (1) the construction of the device; and (2) the use of the device for fungal eradication treatment and transdermal drug delivery enhancement treatment. The beneficial effects achieved by this invention are as follows: This invention is the first to apply the Laval nozzle structure to a portable low-temperature plasma device. The results show that the device can effectively improve the plasma jet performance and active particle content, significantly improve the treatment effect of fungal infections of the skin and nails and the transdermal drug penetration efficiency, while solving the problems of large size, reliance on external power supply, and complex operation of traditional plasma devices. Therefore, using this invention for the treatment of fungal infections of the skin and nails and for enhanced transdermal drug delivery has advantages such as ease of operation, high safety, non-invasiveness, and high efficiency, and thus has potential application prospects in the field of skin disease treatment and transdermal drug delivery.

This application belongs to the field of microbial technology, specifically relating to the application of a strain of Metarhizium anisopliae JXASMS-01 and its extract in pest control. This Metarhizium anisopliae (… Metarhizium The extract of *Metarhizium anisopliae* sp. JXASMS-01 was deposited on June 8, 2022, at the China Center for Type Culture Collection (CCTCC), No. 299, Bayi Road, Wuchang District, Wuhan, Hubei Province, China, with accession number CCTCC NO: M 2022833. This extract exhibits good killing effects against cotton bollworms and beet armyworms, without the drawbacks of chemical pesticides, enabling sustainable control of lepidopteran pests.

The utility model relates to the technical field of food processing, in particular to a quick-frozen fruit and vegetable fixation machine which comprises a mounting table placed on the ground, the top end of the mounting table is fixedly connected with supporting plates which are symmetrically distributed, a fixation box is arranged between the inner walls of the supporting plates, a servo motor is arranged at the top end of the mounting table, and the servo motor is connected with the mounting table. The servo motor is connected with a rotating shaft through a rotating structure, the top end of the supporting plate is rotationally connected with a through hole rotating shaft, the through hole rotating shaft is connected with a water storage tank through a water injection structure, and a supporting frame is arranged at the bottom end of the water storage tank. Through mutual cooperation of the rotating structure, the water injection structure, the sealing door, the filtering opening and the waste water recycling box, fruits and vegetables can rotate simultaneously when being subjected to hot water soaking treatment and recycling in the enzyme deactivating box, so that the fruits and vegetables are soaked in the enzyme deactivating box more uniformly, the fruits and the vegetables can be in more comprehensive contact with hot water, and the water quality of the fruits and the vegetables is improved. The fixation effect is greatly improved, and the working efficiency is greatly improved.

The invention relates to a Nile red-based photosensitizer as well as preparation and application thereof, and develops a series of Nile red-based photosensitizers, the structural formula of which is as follows: # imgabs0. By changing the electron donating ability of a donor, the Nile red-based photosensitizers not only have profound influence on the structure of the photosensitizers, but also have important significance on active oxygen generation of the photosensitizers. The NTPA disclosed by the invention has ultrahigh active oxygen generation capacity, has huge potential of resisting multiple drug-resistant bacteria and promoting healing of subcutaneous abscess wounds, and shows the most excellent photodynamic therapy performance. The yield of active oxygen can exceed 470 times within 5 minutes under the irradiation of white light, the NTPA nanoparticles (NPs) show extremely high killing capacity on various drug-resistant bacteria in vitro, the in-vitro bacteriostasis rate can reach 99.9%, and the NTPA nanoparticles also show excellent sterilization and wound healing promoting capacity on the living body level and have huge application prospects.

An antibody-drug conjugate, comprising a bispecific antibody targeting HER2 or an antigen-binding fragment thereof. Also provided are a preparation method for and an application of the antibody-drug conjugate, and a pharmaceutical composition comprising the antibody-drug conjugate. The antibody-drug conjugate can effectively kill tumors.

A GPC3-targeting antibody-interferon α fusion protein and a use thereof are disclosed in this invention. The fusion protein consists of an A chain and a B chain; wherein the amino acid sequence of the A chain is as shown in SEQ ID NO: 1, and the amino acid sequence of the B chain is as shown in SEQ ID NO: 2. The killing effect on target cells, especially tumor cells, can be significantly improved, and toxic side effects caused by binding to non-target cells are significantly reduced. The fusion protein has better safety, lower production cost, and good freeze-thaw stability.

The invention belongs to the technical field of microorganisms, and particularly relates to a bacteriophage for splitting bovine-derived salmonella and application of the bacteriophage. The technical problem to be solved by the invention is to provide a new choice for treating infection of bovine-derived salmonella. According to the technical scheme, the invention relates to a bacteriophage Seoulvirus GX2401 for splitting bovine-derived salmonella, wherein the preservation number of the bacteriophage Seoulvirus GX2401 is CCTCC (China Center for Type Culture Collection) NO: M20241156. The bacteriophage is a wide host spectrum thallus, can split six different salmonella, has a wide antibacterial spectrum, and can be applied to preparation of drugs for preventing and treating bovine salmonella infection diseases.

The utility model provides a trapping and killing device for mosquito prevention and control, belongs to the technical field of mosquito killing, and aims to solve the problem that in the long-term use process of an existing power grid for killing mosquitoes, killed mosquito corpses can be attached to the surface and meshes of the power grid, and the mosquito killing effect is weakened. The insect trapping chamber is fixedly connected to the upper surface of the lamp post; the two power grids are dispersedly and fixedly connected to the left side and the right side of the insect trapping chamber; the two driving belt wheels are dispersedly, coaxially and fixedly connected to the outer side of a rotating shaft of the driving motor; the two anti-blocking cleaning assemblies are arranged below the roof in a scattered mode; the insect trapping assembly is arranged in the insect trapping chamber. By means of the driving motor and the anti-blocking cleaning assembly, the sweeping brush is driven to automatically remove residues of the power grid, the light transmission type and cleanliness of the power grid are kept, it is ensured that mosquitoes are continuously and efficiently killed at night, and attraction is enhanced all day long and the mosquito killing efficiency is improved through the mosquito luring lamp and the smell diffusion box.

The utility model discloses a dual-purpose electric sprayer for spraying powder and liquid, which comprises a shell 2, a lithium battery 1, an air pump 3, a powder spraying pipe 5, an air nozzle 9 and a medicine tank 8 in threaded connection, a powder outlet hole 4 communicated with the outside is arranged at a main body part of the front end of the shell 2, which is connected with the medicine tank 8, a detachable water feeding pipe 7 is arranged at the powder outlet hole 4, and a one-way valve is arranged on the water feeding pipe 7. The front end of the main body part is connected with a bendable powder spraying pipe 5, and the end head of the powder spraying pipe 5 is provided with a spraying head for spraying water mist, so that the device not only can be used for spraying the liquid medicine for retaining and spraying to prevent termites, but also can be used for synchronously spraying insecticide powder into termite nests for killing the nests by adjusting and adding the insecticide powder; the structure is simple and effect is good.

The invention belongs to the technical field of microorganisms, and discloses preparation, separation and purification methods and application of lactobacillus casei IOB-P9 anti-helicobacter pylori active substance separation.The preparation, separation and purification methods of the active substance separationcomprises the following steps that lactobacillus casei IOB-P9 is cultured, and active ingredients are prepared; performing macroporous adsorption chromatography separation on the active ingredients; separating active components by an anion exchange method; performing gel filtration chromatography separation on the active ingredients; and verifying the activity of the active component to obtain the active component of the lactobacillus casei IOB-P9. Active substances in the lactobacillus casei IOB-P9 obtained according to the method have certain sensitivity to protease, which indicates that the bacteriostatic active substances are protein or peptide substances. In addition, the bacteriostatic active substance has better thermal stability, is not easy to dissolve in organic reagents and has long preservation time, so that the bacteriostatic active substance is beneficial to storage and transportation and has higher production and application values.

The invention discloses medicinal incense with the effect of resolving dampness by aromatics and a preparation method of the medicinal incense. The medicinal incense comprises agastache rugosus, rhizoma atractylodis, honeysuckle, mint, chrysanthemum, houttuynia cordata and folia perillae acutae. The incense is prepared by a series of processes of incense preparation, incense arrangement, incense airing, incense collection, incense storage and the like. Safe and effective natural traditional Chinese medicine powder and natural Indonesia nanmu sticky powder are used, no chemical additive is added, and the composition is green, safe and free of toxic and side effects; indoor air peculiar smell is improved, air is purified, and people can feel relaxed and pleasant; the production process is simple, low in cost, suitable for industrial production and large-scale popularization and application, and wide in market prospect.

The invention relates to an efficient special cockroach pesticide as well as a preparation method and application thereof, and aims to provide a cockroach control scheme which is remarkable in killing effect, high in safety and environmentally friendly. According to the cockroach pesticide, 0.5% fipronil powder and 80% imidacloprid powder are mainly selected as main active ingredients, and efficient killing of cockroaches is achieved through a reasonable proportion and a preparation process. Meanwhile, bait components such as wheat flour and white granulated sugar and diatomite are added as carrier materials, so that the dispersibility, stability and attraction of the medicine are improved. In practical application, the flexibility of the preparation method and the use strategy is adjusted according to different environments and the severity of cockroach problems, and a comprehensive control strategy is provided by comparing the pesticide effects of cockroach pesticide samples of different types and concentrations in different environments. The strategy can comprehensively control reproduction and diffusion of the cockroaches, and meanwhile the risk that the cockroaches generate resistance to specific chemicals is reduced.