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42results about How to "Improve migration ability" patented technology

Method, device and equipment for voiceprint recognition system to resist attack and medium

PendingCN121963772AImprove migration abilityImprove stabilitySpeech analysisAttacker modelAlgorithm
The invention discloses a voiceprint recognition system attack resisting method and device, equipment and a medium, by constructing a shadow voice sample set and a substitution model, dependence on target speaker data and query capability is reduced, and privacy risk and query overhead are reduced; meanwhile, two types of substitution models are trained based on an information theory method, so that the mobility and stability of the models are improved, and the generalization ability is enhanced; besides, the attacker model adopts a specific architecture and combines an alternate training strategy, so that attack loss and prediction probability difference are optimized, imperceptibility and attack effectiveness are balanced, and tone quality reduction or attack failure is avoided; and finally, through systematic training and optimization, a more uniform evaluation caliber is expected to be provided, and more reliable guidance is provided for engineering landing and risk evaluation.
Owner:GUIZHOU UNIV

Depth time sequence clustering enhancement-based disease deterioration risk identification method and system

PendingCN121768650AImprove discrimination abilityImprove migration abilityHealth-index calculationMedical automated diagnosisLaboratory Test ResultDisease
The invention relates to the technical field of clinical medical treatment, and discloses a disease deterioration risk identification method and system based on depth time sequence clustering enhancement, and the method comprises the steps: 1, obtaining multi-modal clinical sequence data of a patient, including physiological indexes of a time sequence, a laboratory detection result, historical diseases and medication data; 2, performing feature extraction and classification on the patient sequences by adopting a knowledge enhanced sequence clustering method, and grouping the patient sequences according to future outcome distribution of the patient sequences; 3, enabling the model to quickly adapt to a prediction task of a new patient subgroup through a meta-training process; and step 4, based on the trained meta-model, carrying out rapid adaptation on the new patient subtype, and predicting the possibility that the new patient subtype has a deterioration event in a certain time window in the future. The method and the system can effectively learn the disease change mode of the patient under the condition of limited clinical data, improve the prediction accuracy of the new patient subgroup, and are especially suitable for clinical prediction scenes under the condition of small samples.
Owner:ZHONGBEI UNIV

An air electrode material for RSOC and its preparation method

This invention relates to an air electrode material and its preparation method. The preparation method includes: using metal salts of Ce, Pr, La, Ba, and Sr, metal salts of Co, and a fluorine source as raw materials, and preparing a fluorine-containing perovskite precursor according to a stoichiometric ratio; pretreating the precursor and then sintering it to obtain a composite powder; the composite powder includes a fluorine-containing perovskite main phase and a fluorine-containing CeO2 nanophase; pulverizing and sieving the composite powder to obtain air electrode powder; the fluorine-containing perovskite main phase is an A-site high-entropy perovskite oxide; the fluorine-containing CeO2 nanophase is precipitated through the self-assembly of some Ce elements during sintering; the fluorine-containing CeO2 nanophase is dispersed inside the main phase grains or at grain boundaries, and forms a strongly coupled heterogeneous interface with the main phase. This invention solves the technical problems of poor surface exchange activity, bulk diffusion transport, and long-term stability of existing air electrodes.
Owner:SOUTHEAST UNIV

Vehicle confrontation camouflage generation method and system for DE-YOLO cross-modal detection

PendingCN121962391ASolve the problem of attack failureEfficient cross-modal physical attackImage enhancementInternal combustion piston enginesPattern recognitionEngineering
The invention discloses a vehicle confrontation camouflage generation method and system for DE-YOLO cross-modal detection, and the method comprises the steps: employing a three-dimensional neural network renderer to initialize a full-coverage texture as an attack patch, covering the surface of a target object, and preliminarily simulating a basic attack scene; simulating a multi-factor interference scene in combination with a diffusion generation model, and generating target vehicle pictures in different scenes; forming an input batch by using the generated target vehicle pictures in different scenes, and inputting the input batch into a model DE-YOLO cross-modal detector to obtain three different-scale infrared feature maps and visible light feature maps in different scenes; and fusing the feature patterns of different scales into a cross-modal loss item, and performing back propagation optimization to generate infrared and visible light cross-modal full-coverage confrontation textures which are attached to the surface of the vehicle. According to the method, the neural network renderer is adopted to generate the full-coverage texture to serve as the attack patch to cover the surface of the target object, the target detection system is attacked, and the attack failure problem under multi-factor interference is solved.
Owner:江淮前沿技术协同创新中心

Active polypeptide for promoting healing of oral ulcer and application thereof

The invention discloses an active polypeptide for promoting healing of oral ulcer and application thereof, and belongs to the technical field of biological medicines. The amino acid sequence of the active polypeptide NPTX3 capable of promoting healing of the oral ulcer is DLKPIAEDIPSLEK. An in-vitro experiment result shows that the polypeptide NPTX3 can remarkably promote the scratch closure of the human immortalized keratinocytes at the concentration as low as 500 pM. Transwell migration experiments further prove that the polypeptide NPTX3 can obviously enhance the migration ability of HaCaT cells at the concentrations of 1nM and 10nM, which prompts that the polypeptide NPTX3 may accelerate wound repair by promoting epithelial cell migration. In an SD (Sprague Dawley) rat oral ulcer model, the ulcer healing rate can be obviously improved by locally applying the polypeptide NPTX3 (1 nM, 10 nM). The polypeptide NPTX3 provided by the invention shows excellent activity of promoting cell migration and tissue repair at an extremely low dose, has the advantages of low effective dose, strong biological activity, high safety and the like, and provides an efficient and mild new choice for drug treatment of oral ulcer.
Owner:YUNNAN MINZU UNIV

A low-carbon cementitious material prepared from waste incineration fly ash and a method for preparing the same

ActiveCN121609523Bincreased toxicityImprove migration abilityProcess engineeringEnvironmental engineering
The application discloses a kind of low-carbon cementing material by waste incineration fly ash excited ore powder and preparation method thereof, by weight percentage, including the following components: modified waste incineration fly ash 8~12%, ion complex component 1~3%, composite shrinkage component 2~6%, ore powder 55~65%, water 23~28%.Preparation method includes the following steps: S1, preparation modified waste incineration fly ash, ion complex component, composite shrinkage component;S2, modified waste incineration fly ash, ion complex component, composite shrinkage component, ore powder, mixing water, fully mixed and stirred evenly, can obtain the low-carbon cementing material by waste incineration fly ash excited ore powder described in the application.In the aspect of component design, the application is environmentally friendly, low cost, in the performance aspect, the flow rate can be adjusted, the mechanical properties are excellent, the volume shrinkage is small.
Owner:XI'AN UNIVERSITY OF ARCHITECTURE AND TECHNOLOGY

SnTe-based thermoelectric material and preparation method thereof

The application discloses a SnTe-based thermoelectric material and a preparation method thereof, and belongs to the technical field of thermoelectricity. The application adopts high-purity metal elements as raw materials, and the raw materials are mixed according to a stoichiometric ratio, and then a cast ingot is obtained through a melting reaction after vacuum packaging. Subsequently, the cast ingot is subjected to high-temperature annealing treatment. After the cast ingot subjected to the high-temperature annealing treatment is ground into powder, a dense block-shaped SnTe-based thermoelectric material is formed through discharge plasma sintering. The chemical formula of the SnTe-based thermoelectric material is Sn 2.9‑X W X Te 2.9 -(In2Te3) 0.03 -(Cu2Te) 0.18 The application significantly improves the thermoelectric figure of merit of the SnTe-based thermoelectric material and improves the thermoelectric performance of the SnTe-based thermoelectric material by doping tungsten elements in the SnTe matrix and compounding the two metal compounds of In2Te3 and Cu2Te.
Owner:GUANGZHOU UNIVERSITY

Wind turbine generator gearbox state monitoring and fault early warning method and system

The invention discloses a wind turbine generator gearbox state monitoring and fault early warning method and system. The method comprises the following steps: defining a key part of a gearbox of a wind turbine generator as a flexible body, and constructing a multi-body dynamic model based on the flexible body; the multi-body dynamics model receives input multi-source time sequence data, then performs feature extraction and multi-index fault early warning algorithm processing, and outputs signal abnormal information for the current multi-source time sequence data; the signal abnormal information is gearbox fault data; constructing a mixed data set guided by a physical mechanism and performing data enhancement; and inputting a spatial-temporal feature coding fault diagnosis model based on the enhanced mixed data set, and then outputting a health index. According to the intelligent early warning system for the wind turbine generator gearbox, through the technical innovation of making up for data missing through modeling simulation, improving diagnosis precision through an intelligent algorithm and guaranteeing real-time early warning through edge calculation, a set of intelligent early warning system for the wind turbine generator gearbox which is high in precision, low in time delay and strong in generalization is successfully constructed.
Owner:NORTH CHINA ELECTRIC POWER UNIV +2

A composition, pharmaceutical preparation and use for treating a vascular-bone coupling imbalance disease

PendingCN122351273Apromote new lifeReduce levels of apoptosisDiseaseVascular endothelium
The application belongs to the field of treating blood vessel-bone coupling imbalance diseases in traditional Chinese medicine, and particularly relates to a composition for treating blood vessel-bone coupling imbalance diseases, a pharmaceutical preparation and application. Geniposide alone or in combination with crocin I can effectively reduce endothelial cell damage under pathological stimulation conditions, reduce the level of cell apoptosis and the degree of oxidative stress, improve the vascular endothelial function state, and can also significantly inhibit osteoclast differentiation, reduce the number of mature osteoclasts, and reduce bone resorption activity, thereby being conducive to restoring the dynamic balance between bone formation and bone resorption.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES +1

Hafnium zirconium oxide all-component ferroelectric characteristic and fatigue optimization method based on machine learning potential

PendingCN121999946AAccurate calculation of polarization responsefill technology gapsBiological modelsComputational theoretical chemistryData setOriginal data
The invention relates to a hafnium zirconium oxide all-component ferroelectric characteristic and fatigue optimization method based on machine learning potential. The construction method comprises the following steps: step 1, acquiring atomic configuration, energy, stress and electric dipole moment data of HfxZr1-xO2 under different components x (0 < = x < = 1) as an original data set; 2, training a multi-task machine learning potential model by using a deep learning algorithm, wherein the model comprises an energy-force prediction branch and an electric dipole moment prediction branch; 3, performing molecular dynamics evolution under different temperatures and external electric fields to obtain a change curve of the polarization intensity along with the cycle period; and step 4, screening an optimal material component according to the nonlinear corresponding relationship between the fatigue rate and the Hf content obtained by simulation. Compared with the prior art, the method has the advantages that the training data set covering all-component space is constructed, the machine learning potential model capable of synchronously describing energy, force and electric dipole moment is obtained through deep neural network training, and the regulation rule of the Hf doping proportion on the crystal phase stability is disclosed through large-scale molecular dynamics simulation; and the relationship between the domain wall movement rate and the fatigue rate is quantified, and theoretical guidance of atomic scale is provided for component design of the FeRAM device.
Owner:PEKING UNIV +1

A high-nitrogen iron-nickel-based alloy protective slag

PendingCN122500153Alow softening pointincrease nucleation point
The application belongs to the technical field of continuous casting and particularly relates to a high-nitrogen Fe-Ni-based alloy protective slag. According to mass percentage, the high-nitrogen Fe-Ni-based alloy protective slag comprises SrO: 14-16%, CaF2: 11.5-13.5%, SiO2: 24-26%, Na2O+K2O: 12-14%, B2O3: 7-9%, Al2O3: <1%, MgO: 8-10%, La2O3: 10-12%, and the rest is carbonaceous material and inevitable impurities. Through accurate slag system design and component regulation, the protective slag has excellent performances of rapid slag formation, high lubrication and phased heat control, effectively solves the crack problem in the high-nitrogen Fe-Ni-based alloy continuous casting process, and meets the actual needs of the large-scale production of the continuous casting.
Owner:SHANXI TAIGANG STAINLESS STEEL CO LTD

Biomarker for diagnosing pulmonary fibrosis and application of biomarker

The invention discloses a biomarker for diagnosing pulmonary fibrosis and application of the biomarker, and belongs to the technical field of biomarkers in clinical medicine. The biological marker for preparing and diagnosing pulmonary fibrosis is a nerve growth factor NGF, the nerve growth factor NGF can remarkably promote differentiation of lung fibroblast MRC5 cells, and along with expression increase of a receptor TrkA of the lung fibroblast MRC5 cells, the migration capacity and the multiplication capacity of the lung fibroblast MRC5 cells are remarkably enhanced. Meanwhile, the NGF also aggravates the formation of the BLM-induced pulmonary fibrosis of the mouse. Therefore, the nerve growth factor NGF as the biomarker has accurate and specific detection and auxiliary diagnosis on pulmonary fibrosis, especially idiopathic pulmonary fibrosis (IPF).
Owner:GUIZHOU PROVINCIAL PEOPLES HOSPITAL

A method for preparing high-strontium mineral water with improved strontium absorption rate and application thereof

The application relates to a high-strontium mineral water preparation method for improving strontium absorption and application of the same. The method comprises raw water input, pretreatment and purification, two-stage nanofiltration grading purification, strontium concentrate liquid and low-mineral dialysis, constant-temperature targeted chelation reaction, chelated strontium mother liquor, sterile blending, calcium-strontium ratio precise control, improvement of strontium absorption and utilization, double strategies of calcium-strontium ratio lock control and ion removal, solution of competition of calcium and magnesium ions on strontium absorption from the root, mild reaction in the whole process, no high temperature and high pressure, no introduction of harmful by-products, all raw materials meeting national food safety standards, no taste difference, no peculiar smell and no astringency.
Owner:YANGZHOU FENGQUAN DRINKING WATER CO LTD

Adversarial sample generation method and system based on frequency domain guided multi-feature attention

The application discloses a frequency domain guidance-based multi-feature attention adversarial sample generation method and system. In the method, the target recognition loss of the initial adversarial sample of each round is calculated in the iterative generation of the final adversarial sample; the multi-scale features of the initial adversarial sample of the round are extracted, and the multi-scale feature gradient is calculated; the spatial domain feature weight is calculated and determined according to the target recognition loss and the multi-scale feature gradient; the spatial domain feature weight is subjected to frequency domain transformation and band-stop filtering processing to obtain the filtered weight; the filtered weight is reconstructed back to the spatial domain to obtain the frequency domain guidance weight; the frequency domain guidance weight and the multi-scale feature gradient are point-multiplication fused to obtain the fusion gradient; the initial adversarial sample of the next round is obtained by updating the initial adversarial sample of the round through the fusion gradient, and the initial adversarial sample of the next round is obtained. The generated adversarial sample has good cross-model migration.
Owner:QILU UNIVERSITY OF TECHNOLOGY (SHANDONG ACADEMY OF SCIENCES) +1

Lithium-rich manganese-based positive electrode material, preparation method thereof, positive plate and battery

PendingCN121983570AIncrease migration coefficientImprove conduction abilityCell electrodesSecondary cellsElectrical batteryHigh energy
The invention provides a lithium-rich manganese-based positive electrode material and a preparation method thereof, a positive plate and a battery. The lithium-rich manganese-based positive electrode material comprises a lithium-rich manganese-based core material and a coating layer coating the lithium-rich manganese-based core material, the alkali metal layer of the lithium-rich manganese-based core material at least comprises Mg element, and the coating layer comprises lithium fluoride. The lithium-rich manganese-based positive electrode material disclosed by the invention has high capacity, high structural stability and excellent interface durability, and can meet the performance requirements of a high-energy-density battery under complex working conditions.
Owner:NINGBO RONBAY LITHIUM BATTERY MATERIAL CO LTD

Abnormality detection method and device for graph data

The invention provides an anomaly detection method and device for graph data. The detection method comprises the steps that graph data of a target graph are obtained, the graph data comprise n nodes and the connection relation between the nodes, and each node has first feature data composed of d attributes; and partial nodes in the n nodes have labels representing the abnormal degrees thereof. And then determining second feature data, related to the graph structure, of each node, including processing the first feature data of each node by using a group of band-pass filters determined according to the connection relationship to obtain high-frequency abnormal features. The table data is constructed, and the single row data records the comprehensive feature data of the single node and comprises the first feature data and the second feature data. Then, the table data and the labels of the partial nodes are input into the table basic model, and the abnormal degree of the other nodes without the labels is predicted.
Owner:ALIPAY (HANGZHOU) INFORMATION TECH CO LTD

Cornu cervi pantotrichum tissue cell culture method

PendingCN121950686AImprove migration abilityMigration efficiency will not be affectedCell dissociation methodsCulture processCell migrationTrypsin
The invention relates to the technical field of tissue engineering, and particularly discloses a pilose antler tissue cell culture method which comprises the following steps: S1, cell in-vitro culture; s2, directional induced differentiation; step S3, ossification induction; the induction culture medium 1, the induction culture medium 2 and the ossification induction culture medium are added, amphotericin B capable of covering the fungal pollution risk is added into the induction culture medium 1, fetal calf serum contained in the induction culture medium 1 can neutralize trypsin, recombinant human HGF contained in the induction culture medium 2 can improve the migration ability of cells, and meanwhile, the ossification induction culture medium can be used for preparing the ossification culture medium. The recombinant human bFGF can synergistically promote proliferation, so that emigrated cells are quickly accumulated, and the situation that the cell density is too low due to insufficient proliferation after emigration is avoided; ascorbic acid-2-phosphate contained in the ossification induction culture medium can avoid oxidation failure of ascorbic acid, and the cell emigration efficiency is improved through the synergistic effect of the substances.
Owner:DONGGUAN SHIDU BIOTECHNOLOGY CO LTD

Database migration method and device and electronic equipment

PendingCN121764900AImprove migration abilityAffect system functionalityDatabase updatingSpecial data processing applicationsEngineeringData mining
The invention discloses a database migration method and device and electronic equipment, and relates to the technical field of database migration, and the method comprises the steps that under the condition that a target system needs database migration, a first module in the target system is recognized; under the condition that the first module exists in the target system, updating the first module based on a target transaction isolation function supported by the target database; under the condition that the first module does not exist in the target system, identifying a second module in the target system; under the condition that the second module exists in the target system, updating the second module based on a preset mark; after updating of the first module / the second module is completed, database migration operation is executed on the target system. According to the database migration method and device, the technical problems that in the database migration process, due to the fact that the function supported by the source database and the function supported by the target database are different, the system function is abnormal after migration, and the performance is reduced are solved.
Owner:TRAVELSKY TECHNOLOGY LIMITED

A sulfur cathode material and its preparation method

ActiveCN115911377BImprove migration abilityavoid consumptionQuaternary ammonium cationElectrical battery
This invention discloses a sulfur-containing cathode material and its preparation method, belonging to the field of lithium-sulfur battery technology. The method uses a quaternary ammonium polymer containing nitrate as a cathode binder, dispersed with a conductive agent and a sulfur-containing cathode material in deionized water to obtain a cathode slurry. The slurry is then coated onto aluminum foil and vacuum dried to obtain a cathode sheet. The quaternary ammonium cation backbone in the binder can adsorb polysulfides, improving lithium-ion migration capacity, while simultaneously preventing the rapid and uncontrollable consumption of nitrate, thereby extending the lifespan of the lithium-sulfur battery.
Owner:RES INST OF CHEM DEFENSE PLA ACAD OF MILITARY SCI

Audio-visual navigation method combining explicit acoustic geometric reasoning and auxiliary supervision

The invention discloses an audio-visual navigation method combining explicit acoustic geometric reasoning and auxiliary supervision, and belongs to the field of intelligent and robot autonomous navigation. The invention aims to solve the problems of weak geometric perception capability and poor generalization of the existing audio-visual navigation method in a perception limited and unknown environment. The method comprises the following steps: acquiring a binaural spectrogram and a visual image of an intelligent agent and extracting features; inputting the auditory features into an explicit geometric reasoning module (AGR), and outputting a high-dimensional geometric representation vector for decision making and a sound source distance and azimuth angle prediction value for auxiliary supervision in parallel through a shared coding and multi-head decoupling structure; and fusing the geometric representation vector and the visual feature, and inputting into a recurrent neural network to generate a navigation action. In a training stage, real geometric information of a simulation environment is utilized to construct auxiliary regression loss, and a dynamic weighting mechanism based on uncertainty is introduced to adaptively balance weights of a navigation task and a geometric auxiliary task. According to the method, the agent is endowed with the explicit perception ability of sound listening and position distinguishing, the model is forced to learn the acoustic physical law, and the navigation robustness and generalization ability in a visual blind area and an unknown environment are remarkably improved.
Owner:XINJIANG UNIVERSITY

Music style transfer method and device, computer device and storage medium

ActiveCN116469359BSimplify the decoupling processDetermine whether migration is successfulElectrophonic musical instrumentsEnergy efficient computingEngineeringRhythm
The application discloses a music style migration method, which comprises the following steps: obtaining to-be-combined music and to-be-migrated music; inputting the to-be-combined music and the to-be-migrated music into a preset style decoupling model respectively to obtain a first pitch content code, a second pitch content code and a rhythm code; inputting the first pitch content code and the rhythm code into a first decoder to obtain migrated music; inputting the second pitch content code and the rhythm code into a second decoder to obtain reconstructed music; detecting the migrated music and the reconstructed music by using a discriminator to obtain a style migration detection result; and determining the migrated music as target music when the style migration detection result represents successful migration. The preset style decoupling model is used for completely decoupling music, thereby avoiding mutual mixing between pitch content and rhythm style. The discriminator is used for detecting the migrated music and the reconstructed music, thereby ensuring successful rhythm style migration and improving the effect of music style migration.
Owner:PING AN TECH (SHENZHEN) CO LTD

Adversarial Example Generation Method and Apparatus Based on Artificial Intelligence Image Generation Model

PendingCN122090196ASolving the problem of low mobilityImprove migration abilityCharacter and pattern recognitionBiological modelsPattern recognitionSemantic matching
This application relates to a method and apparatus for generating adversarial examples based on an artificial intelligence image generation model. The method includes: acquiring a pre-constructed adversarial training dataset; the adversarial training dataset includes original image samples and their corresponding text labels, and initial adversarial examples generated based on the original image samples; constructing a constraint function based on a pre-constructed semantic matching loss function, the initial adversarial examples, and the semantic mask of the original image samples; the semantic matching loss function is constructed based on the original image samples and their text labels; adjusting the weights of target neurons in each layer of the artificial intelligence image generation model based on the constraint function to obtain an adjusted artificial intelligence image generation model; and using the adjusted artificial intelligence image generation model to generate target adversarial examples corresponding to the original image samples. This solves the problem of low adversarial example transferability and improves adversarial example transferability, thereby enabling adaptation to black-box model scenarios.
Owner:HANGZHOU HIGH-TECH ZONE (BINJIANG) INSTITUTE OF BLOCKCHAIN & DATA SECURITY +1

An intelligent migration countermeasure method and system for electromagnetic signal recognition under incomplete information

ActiveCN115600083BcreativeImprove migration abilitySecuring communicationNeural learning methodsNetwork conditionsEngineering
This invention belongs to the field of artificial intelligence algorithm technology and discloses an intelligent transfer adversarial method and system for electromagnetic signal recognition under incomplete information. First, multiple models of alternative target networks with incomplete information are constructed in parallel, and these alternative models are trained using an evolutionary strategy based on a prior knowledge matrix. Then, an ensemble network model is generated based on the trained alternative models, and a fully connected layer and a layer with feature-level weighted fusion are designed. Finally, an optimized adversarial method for electromagnetic spatial signal recognition tasks is designed, generating adversarial samples under the ensemble model, and transferring these adversarial samples to the target network to achieve adversarial capabilities against the target network. This invention can effectively achieve adversarial capabilities against the target network when the target network information is unknown, and it still exhibits good transfer adversarial performance under the same signal recognition task and different unknown target network conditions.
Owner:XIDIAN UNIV

Transferable adversarial sample generation method and device based on wavelet transform and multi-scale filling, and storage medium

PendingCN121982451AImprove migration abilityPrecisely expose security vulnerabilitiesCharacter and pattern recognitionBiological modelsAlgorithmEngineering
The invention relates to a transferable adversarial sample generation method and device based on wavelet transform and multi-scale filling, and a storage medium, and the method comprises the following steps: obtaining an input image, converting the input image from a spatial domain to a frequency domain through wavelet transform, and carrying out the random block disruption of a high-frequency component block, and obtaining a preprocessed image; mI-FGSM-based sample updating is performed on the preprocessed image, and in the updating process, a global random multi-scale filling method is used, MI-FGSM input is transformed from multiple angles of a space domain and a frequency domain, a plurality of substitution models are combined, combined gradient loss is calculated, and training is performed to obtain an adversarial sample. Compared with the prior art, the method has the advantages of remarkably improving the migration capability of the adversarial sample among the black box models, improving the attack success rate and the like.
Owner:THE THIRD RES INST OF MIN OF PUBLIC SECURITY +1

Active polypeptide NP-VV-3 capable of promoting healing of oral ulcer and application of active polypeptide NP-VV-3

The invention discloses an active polypeptide NP-VV-3 capable of promoting healing of oral ulcer and application of the active polypeptide NP-VV-3, and belongs to the technical field of biological medicines. The amino acid sequence of the active polypeptide NP-VV-3 capable of promoting healing of the oral ulcer is VVPAFVLLKKAIRIMFKRNC. The amino acid sequence of the active polypeptide NP-VV-3 capable of promoting healing of the oral ulcer is shown in the specification. In an in-vitro experiment, the polypeptide NP-VV-3 can remarkably promote scratch closure of human immortalized keratinocytes at the concentration as low as 1 nM, and shows dose-dependent healing promotion capability at the concentrations of 1 nM and 10 nM; transwell migration experiments further prove that the polypeptide NP-VV-3 can significantly enhance the migration ability of HaCaT cells at the concentrations of 1 nM and 10 nM, indicating that the polypeptide NP-VV-3 can accelerate wound repair by promoting epithelial cell migration; besides, in an SD rat oral ulcer model, local administration of the polypeptide NP-VV-3 (1 nM, 10 nM and 100 nM) can significantly improve the healing rate of ulcer wounds, and presents a concentration-related trend. The polypeptide NP-VV-3 provided by the invention provides an important candidate molecule for developing a novel, efficient and low-irritation oral ulcer treatment medicine.
Owner:KUNMING MEDICAL UNIVERSITY

A Highly Transferable Adversarial Example Generation Method and Its Application in a Secure Range

PendingCN122087439AImprove migration abilityAchieve systematic cognitionBiological modelsPlatform integrity maintainanceSingular value decompositionCorrelation coefficient
This invention discloses a highly transferable adversarial example generation method and its application in a secure test range. The method applies principal component protected feature perturbation transformation to the intermediate layer feature map of a momentum-based iterative fast gradient symbolic attack framework. It identifies the principal and secondary components of the feature space using singular value decomposition (SVD), quantifies the redundancy between feature channels using Pearson correlation coefficient analysis, and achieves precise feature perturbation using an adaptive mask generation mechanism based on Bernoulli sampling and energy conservation constraints. This method can be embedded as a pluggable module into existing iterative gradient attack processes without modifying the main structure of the basic attack algorithm or retraining the source model. By dynamically registering hook functions during forward propagation to intercept and transform intermediate layer features, it significantly improves the transferability of adversarial examples on unknown target models. The method's high transferability and ease of use in the test range environment are verified, providing users with an effective tool for evaluating model robustness.
Owner:BEIJING JIZHIXIN TECHNOLOGY CO LTD

A multi-level land resource segmentation and migration fine-tuning method with input alignment

This invention discloses a multi-level land resource segmentation migration fine-tuning method with input alignment, comprising the following steps: acquisition and processing of remote sensing image data and label data related to the land resource segmentation task; selection and slicing of sampling areas based on prior knowledge of the study area; data augmentation to expand the dataset and pixel value normalization; partitioning the model dataset using stratified sampling techniques; determining the optimal initial learning rate through hyperparameter optimization, entering input feature alignment, and establishing a quick connection between the input alignment module and the model output; employing three Transformer architectures and their pre-trained models for land resource segmentation, and optimizing the model training process using gradient-value-constrained gradient clipping and two-stage training strategies; step six: segmentation prediction and visualization. This invention improves the model's training efficiency and segmentation performance, achieving high-precision multi-level land resource segmentation and recognition.
Owner:INST OF GEOGRAPHICAL SCI & NATURAL RESOURCE RES CAS

An image data processing method based on heterogeneous multi-agent and frequency domain attention feedback

PendingCN122510592AReduce the number of queriesGuaranteed visual quality
This invention discloses an image data processing method based on heterogeneous multi-agent and frequency domain attention feedback, belonging to the fields of artificial intelligence security and digital image processing technology. The method acquires the image to be processed and real / generated category labels, constructs a heterogeneous agent detection model group containing a convolutional neural network and a visual Transformer; performs discrete cosine transform on the image to estimate frequency domain sensitivity and generate a frequency domain attention mask; adaptively constructs a frequency domain query subspace based on category prior, generates frequency domain integrated initialization data, and performs frequency domain decision boundary search on a target detection model that only returns hard labels; updates the attention mask and query subspace according to query feedback, and finally obtains a pixel-domain processed image that satisfies the perturbation budget through inverse discrete cosine transform. This invention can reduce the number of black-box queries, improve the processing success rate, and maintain image visual quality.
Owner:ANHUI UNIV

Personal and environment matching system and method for treating social distraction of old people

PendingCN121983224AImprove evaluation accuracyBreaking through the limitations of static evaluationForecastingMental therapiesPhysical medicine and rehabilitationOlder people
The invention belongs to the technical field of pension service, and relates to an individual and environment matching system and method for governing social distraction of old people, and the system comprises a data collection and integration module, a matching consistency evaluation module, a matching mode recommendation module and a process feedback regulation and control module. Multi-dimensional longitudinal data are integrated through a data merging analysis technology, a UTADIS multi-criterion classification method is adopted to accurately identify the matching degree and treat dilemma, a fuzzy multi-attribute group decision and a TOPSIS method are combined to recommend a personalized matching mode, and a mixed time-varying effect model and an SOC measurement scheme are utilized to realize dynamic feedback regulation and control; the problems that an existing old-age nursing matching system cannot adapt to the social distraction treatment scene, the evaluation precision is low, and dynamic adjustment lags behind are solved, the pertinence and effectiveness of social distraction treatment are improved, and the method is suitable for the social distraction intervention scene of the old people in the old-age nursing institution.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE

Application of CDH18 gene as target spot in screening medicine for preventing or treating cervical cancer

InactiveCN121899407Aprevent proliferationability to inhibit migrationOrganic active ingredientsPeptidesApoptosisOncology
The invention relates to the technical field of biology, in particular to application of a CDH18 gene serving as a target spot to screening of drugs for preventing or treating cervical cancer, the drugs take the CDH18 gene as the target spot, expression of the CDH18 gene is inhibited or silenced, the proliferation and migration capacity of cervical cancer cells can be enhanced by regulating and controlling a Wnt pathway through overexpression of the CDH18 gene, and the drugs for preventing or treating cervical cancer can be used for preventing or treating cervical cancer. The down-regulation of the CDH18 gene inhibits the expression of beta-catenin, the knock-down of the CDH18 gene can inhibit the proliferation and migration ability of cervical cancer cells by regulating and controlling a Wnt signal pathway, the kaempferide has a certain potential anti-tumor activity effect in the cervical cancer cells, the kaempferide can induce the apoptosis of SiHa and HeLa cells of cervical cancer, and the kaempferide can inhibit the proliferation and migration ability of the cervical cancer cells. Experiments show that the kaempferide inhibits the expression level of Wnt signal pathway related molecules by reducing the expression level of CDH18, further promotes apoptosis of cervical cancer cells and inhibits proliferation and migration of the cervical cancer cells.
Owner:SHIHEZI UNIVERSITY