This invention discloses a suture, comprising a suture body, barbs, a needle, and a locking component. One end of the suture body is connected to the needle, and the other end is connected to the locking component. A plurality of barbs are arranged at intervals on the suture body, with the ends of the barbs extending away from the suture body towards the locking component, and forming a first angle with the suture body. The locking component includes a wall, a limiting part, and an inlet and an outlet correspondingly located at both ends of the wall. The limiting part is located inside the wall and can stop the movement of the suture body from the outlet towards the inlet, thereby automatically locking the suture. This invention's suture, by cooperating with the barb structure and the limiting part of the locking component, allows only unidirectional sliding of the suture, automatically preventing it from retracting, thus achieving knot-free suturing and improving surgical efficiency.