The invention discloses a
bone scaffold fusion design and preparation method based on
mirror image registration, and the method comprises the steps: firstly, based on a three-dimensional medical image of a femoral
defect region of a patient, combining an opposite-side complete femoral CT image, and achieving the automatic recognition and
complementation of the
defect region through the
mirror image transformation and ICP registration technology; after defect boundary extraction is completed, three-dimensional reconstruction is carried out on the individualized outer contour of the left
bone tissue, and an STL format model is exported. According to the
femur functional partition characteristics,
a Diamond structure is adopted in a
cortical bone area to enhance mechanical support, and a Gyandroid structure is selected in a
cancellous bone area to achieve
porosity gradient filling, so that the permeability is optimized, and
cell proliferation is promoted.
Continuous transition among the structures is realized through a
Sigmoid function, and the stability and the biological adaptability of the whole structure are improved. And finally, the
stent model is subjected to
selective laser melting, and a Zn-3Mg
alloy material is utilized to complete printing manufacturing.