533 results about "Femur bone" patented technology

A system for computer assisted navigation during surgery includes a computer platform that operates to register a target surgical area of a patient. In certain cases, a process includes: obtaining a pre-op CT image of a pelvic region of a patient and intra-operatively obtaining a point cloud data about the pelvic region with a navigated instrument, generating a 3D bone model which excludes non-targeted area such as a femur, and then merging the 3D bone model to the point cloud to register the target surgical area.

A system for computer assisted navigation during surgery includes a computer platform that operates to register a target surgical area of a patient. In certain cases, a process includes: obtaining a pre-op CT image of a pelvic region of a patient and intra-operatively obtaining a point cloud data about the pelvic region with a navigated instrument, generating a 3D bone model which excludes non-targeted area such as a femur, and then merging the 3D bone model to the point cloud to register the target surgical area.

A system for computer assisted navigation during surgery includes a computer platform that operates to register a target surgical area of a patient. In certain cases, a process includes: obtaining a pre-op CT image of a pelvic region of a patient and intra-operatively obtaining a point cloud data about the pelvic region with a navigated instrument, generating a 3D bone model which excludes non-targeted area such as a femur, and then merging the 3D bone model to the point cloud to register the target surgical area.

A system for computer assisted navigation during surgery includes a computer platform that operates to register a target surgical area of a patient. In certain cases, a process includes: obtaining a pre-op CT image of a pelvic region of a patient and intra-operatively obtaining a point cloud data about the pelvic region with a navigated instrument, generating a 3D bone model which excludes non-targeted area such as a femur, and then merging the 3D bone model to the point cloud to register the target surgical area.

The invention provides an osteotomy path adjusting system in robot-assisted knee arthroplasty, and belongs to the technical field of knee joint detection. The system comprises a multi-modal data acquisition unit which comprises a knee joint pressure measuring gasket, an optical acquisition module and a kinematics data acquisition module, the knee joint pressure measuring gasket is used for acquiring knee joint pressure signals in an operation, and the optical acquisition module is used for acquiring relative poses of a femur and a tibia; the kinematics data acquisition module is used for acquiring kinematics data of the mechanical arm; the main control calculation unit comprises a data fusion module and a dynamic compensation module, and the data fusion module is used for constructing a synchronous spatio-temporal data set; and the dynamic compensation module is used for outputting a compensation instruction to the mechanical arm to adjust an osteotomy path based on the synchronous spatio-temporal data set, the preoperative predicted pressure prediction matrix and the soft tissue stiffness matrix. The pressure change in the operation can be responded in real time, the operation precision of the knee arthroplasty is improved, and the dependence on the experience of doctors can be reduced.

The invention provides a plant lactobacillus TH13, and the preservation number of the plant lactobacillus TH13 is CGMCC (China General Microbiological Culture Collection Center) NO.32112. The plant lactobacillus TH13 provided by the invention can be used for fermenting folium cortex eucommiae and enzymatically hydrolyzed bone meal, and the fermentation product of the plant lactobacillus TH13 has high content of chlorogenic acid, proline, glycine and lysine. The fermentation product can significantly improve the content of alkaline phosphatase (ALP) and osteocalcin (OCN) in mouse serum and reduce the content of tartrate-resistant acid phosphatase (TRACP). Therefore, the fermentation product can significantly improve the bone mineral density of the femur, increase the number of bone trabecula and significantly reduce the separation degree of the bone trabecula, thereby promoting bone formation of a mouse with senile osteoporosis, inhibiting bone resorption and improving senile bone loss and bone microstructure deterioration. The preparation method of the probiotic preparation containing the plant lactobacillus and the probiotic fermentation product is simple, and large-scale production can be realized.

The invention discloses bifidobacterium longum subsp.infantis capable of promoting bone growth and a metagen thereof, and belongs to the technical field of biology. The bifidobacterium longum subsp. Infantis CCFM1445 provided by the invention can promote the increase of bone volume fraction, femoral bone trabecula thickness and far-end growth plate thickness of mammals in a growth period, reduce the levels of serum bone resorption markers I-type collagen amino-terminal peptide and tartrate-resistant acid phosphatase, improve the levels of serum bone alkaline phosphatase and parathyroid hormone, and improve the clinical application value of the bifidobacterium longum subsp. Infantis CCFM1445. And the relative abundance of the other bacteria in the intestinal flora and the levels of creatine and indole-3-lactic acid are increased. The thermally inactivated bifidobacterium longum subsp. Infantis CCFM1445 can promote the increase of the volume fraction of femoral bones and the number of bone trabecula of malnourished mice and improve the N-terminal propeptide level of serum I-type procollagen. Therefore, the medicine or health care product prepared from the bifidobacterium longum subsp. Infantis CCFM1445 can be used for assisting in regulating bone metabolism and bone mass, and has a wide market prospect.

A proximal femur replacement implant assembly (500, 1000) arranged and configured to replace a head portion of a patient's proximal femur is disclosed. In some examples, the proximal femur replacement implant assembly includes a proximal femur replacement implant (505, 1005) arranged and configured to be coupled to, or inserted into an intramedullary canal of, a remaining portion of a patient's femur. The proximal femur replacement implant being arranged and configured to engage a bone plate (510, 1010, 1050) to, for example, minimize micromotion of the patient's greater trochanter to promote porous in-growth and to constrain movement of the greater trochanter.

The invention belongs to the technical field of biology, and particularly relates to casein phosphopeptides for promoting absorption of calcium, iron and zinc minerals and improving bone health. Casein phosphopeptides containing high-activity peptide fragments are obtained through an optimization process, six mineral elements of calcium, magnesium, copper, iron, zinc and manganese serve as research objects, firstly, mineral utilization of CPP is evaluated through a mineral deficiency rat model, the content of Ca, Mg, Cu, Fe, Zn and Mn in thighbones is increased by 7.12%, 3.56%, 20.76%, 15.84%, 9.94% and 67.12% respectively when the CPP is eaten by 7mg / kg.d; secondly, screening a peptide fragment with calcium absorption promoting activity from the CPP by utilizing a molecular docking technology, and performing functional verification; the invention aims to reveal the action effect of CPP in mineral absorption and utilization from cell and animal levels, and provides a theoretical basis for functional development of CPP.

Computer implemented methods, systems, and computer products employing program code or algorithms for use in customized patient specific hip implants or femoral stems or sleeves having an outer surface that corresponds more closely to the inner surface of the cortical bone of a patient's femur compared to conventional hip implant or femoral stems or sleeves based on population-based design.

The invention discloses a bone scaffold fusion design and preparation method based on mirror image registration, and the method comprises the steps: firstly, based on a three-dimensional medical image of a femoral defect region of a patient, combining an opposite-side complete femoral CT image, and achieving the automatic recognition and complementation of the defect region through the mirror image transformation and ICP registration technology; after defect boundary extraction is completed, three-dimensional reconstruction is carried out on the individualized outer contour of the left bone tissue, and an STL format model is exported. According to the femur functional partition characteristics, a Diamond structure is adopted in a cortical bone area to enhance mechanical support, and a Gyandroid structure is selected in a cancellous bone area to achieve porosity gradient filling, so that the permeability is optimized, and cell proliferation is promoted. Continuous transition among the structures is realized through a Sigmoid function, and the stability and the biological adaptability of the whole structure are improved. And finally, the stent model is subjected to selective laser melting, and a Zn-3Mg alloy material is utilized to complete printing manufacturing.

A system for surgical registration. The system may include at least one computing device in communication with a surgical navigation system and the surgical device. The at least one computing device: a) receiving external bone registration data corresponding to locations on the exterior surface of the femur; b) calculating a first registration transform based on the external bone registration data; c) transforming a first bone removal plan of a surgical plan to the operative coordinate system based on the first registration transform; d) receiving internal bone canal registration data corresponding to at least one of location or orientation data from the inner canal of the femur; e) calculating a second registration transform based on both of the external and internal bone canal bone registration data; and f) transforming a second bone removal plan of the surgical plan to the operative coordinate system based on the second registration transform.

The invention relates to the technical field of medical orthopedic simulation devices, and discloses an orthopedic hip arthroscopic surgery simulation device which comprises a base, a supporting assembly is arranged on the upper side of the base, and a longitudinal moving assembly is arranged above one side of the supporting assembly. Transverse moving assemblies are arranged above the other side of the supporting assembly and on one side of the longitudinal moving assembly, one of the two transverse moving assemblies is provided with a thighbone model in a clamping mode, and the other one of the two transverse moving assemblies is provided with a pelvis model in a clamping mode. The supporting assembly comprises a right-angle table fixedly arranged at the position, close to one side, of the upper end of the base. According to the hip joint arthroscopic surgery simulation device for the orthopedics department, through overall cooperative use, movement in different directions under the normal condition is simulated, movement tracks in different spaces are improved, operation simulation is more flexible and real, and the operation ability of doctors in the surgery is improved.

An image registration system and a method for a femur surgery relates to the field of surgery image registration are provided, before a surgery, DRR projections at different angles are carried out of a three-dimensional femur CT image, femoral coordinate systems and femoral characteristic points are respectively generated and selected on a the two-dimensional DRR projection images and two-dimensional X-ray images. Based on the femoral coordinate systems and the femoral characteristic points, the two-dimensional DRR projection images and the two-dimensional X-ray images are registered, so that the image registration precision is improved, a two-dimensional DRR projection image in the same femoral posture as a femoral posture during a two-dimensional X-ray image scanning can be accurately obtained, which can obtain a real surgical path for surgical navigation, ensures the precision of surgery-assisted navigation, and further improves the surgery quality.

The invention discloses a preparation method of a bionic beetle skeleton implant, and belongs to the field of femoral implantation. The bionic structure characteristics of beetle elytra and cuticle are creatively combined, the mechanical strength and structural stability of the porous nickel-titanium alloy structure implant are effectively improved through the bionic structure design method, and the long-standing stress shielding effect problem of a traditional femoral metal implant is successfully solved; the porous nickel-titanium alloy bionic skeleton structure prepared by adopting a selective laser melting (SLM) technology not only has good mechanical suitability, avoids rejection and shedding reaction with natural bone tissues after implantation, but also can realize a complete shape memory recovery function in a room temperature environment, and has good application prospects in the field of medical orthopedic implantation.

There is provided a computer-implemented method of estimating fetal weight, the method comprising the steps of: a) providing a plurality of ultrasound images comprising image data representative of the anatomical structure and appearance of a head, an abdomen and a femur of a fetus in utero; b) utilising the image data in a first machine learning model comprising one or more neural networks to generate one or more latent space representations of the anatomical structure and appearance of the fetus and one or more predicted measurements of the anatomical structure of the fetus; and c) utilising the one or more predicted measurements and the one or more latent space representations in a second machine learning model to generate an estimated weight of the fetus.

The invention discloses a thighbone inverted-hitting intramedullary nail entry point guide plate and a preparation method thereof, and aims to improve the precision and efficiency of a thighbone intramedullary nail operation. The guide plate comprises an attaching plate and a guide column, the attaching plate is provided with an attaching face precisely matched with a femoral intercondylar fossa and an inner side condylar area, it is ensured that the guide plate can be stably attached to the distal end of the femur, and stable support is provided for an operation. One end of the guide column is connected with the pasting plate, the other end of the guide column extends towards the proximal femur, a guide hole is formed in the guide column, the central axis of the guide hole is strictly collinear with a preset needle inserting point at the distal femur, and reliable guidance is provided for accurate insertion of an intramedullary nail. The guide plate can be prepared before an operation, assists a doctor in quickly positioning a needle inserting point during the operation, effectively shortens the operation time, improves the operation efficiency, reduces the operation risk, and provides an efficient and accurate auxiliary tool for the femoral intramedullary nail operation.

A dynamic ligament repair device includes a suture, a femoral side suture anchor and a threaded screw or housing implant. The screw is configured for placement in the tibia, or alternatively in the femur. A spring is housed inside an axial bore in the threaded screw. In some embodiments, the spring is a compression spring. A moveable spring button is positioned inside the axial bore adjacent a distal end of the spring. The spring button engages the spring directly in some embodiments. In alternative embodiments, an intermediate structure such as a spacer is positioned between the spring button and the spring. The suture extends between the spring button and the suture anchor. When the joint flexes or extends, the spring button travels inside the axial bore and dynamically compresses or relaxes the spring.

The invention discloses a method for designing a bionic femoral stent based on fusion of a VT structure and a TPMS structure, and belongs to the technical field of bionic bone stents. The method comprises the following steps: respectively creating a Diamond unit homogeneous porous structure and a VT porous structure; and creating a Ramp fusion function, substituting the homogeneous porous structure of the Diamond unit and the Ramp fusion function into a Mix instruction, and then sequentially substituting the VT porous structures into the Mix instruction to generate a fusion model. The homogeneous porous structure of the Diamond unit and the VT porous structure are subjected to radial smooth fusion, smooth connection is realized at the fusion position, the service life of the porous structure serving as the bionic bone scaffold is shortened, the smooth surface of the D unit and the periodic structure uniformly conduct stress, the rounded Thiessen polygonal structure further disperses stress, and the stress dispersion and synergistic effects are achieved. The bionic femoral stent constructed by the invention can simulate natural bones, promote cell adhesion, proliferation and differentiation, and optimize transportation of nutrient substances and metabolic wastes. And the smooth fusion interface reduces cell damage and reduces immunological rejection.

The invention discloses bifidobacterium longum subsp.longum capable of improving the physiological activity function of vitamin D and maintaining bone health and application of the bifidobacterium longum subsp.longum, and belongs to the technical field of biological medicine. The bifidobacterium longum subsp. Longum CCFM1448 provided by the invention can obviously improve the total bone mineral density, the bone mineral density of distal femur bone trabecula, the thickness of the bone trabecula, the number of the bone trabecula, the connectivity of the bone trabecula and the bone volume fraction of an osteoporosis mouse, and obviously reduce the separation degree of the bone trabecula of the osteoporosis mouse; the content of a vitamin D metabolite 1, 25-dihydroxy vitamin D in serum of a mouse with osteoporosis is remarkably increased, the content of serum calcium and alkaline phosphatase in the serum of the mouse with osteoporosis is reduced, and the level of osteocalcin and I-type procollagen amino-terminal original peptide in the serum is increased. Therefore, the bifidobacterium longum subsp. Longum CCFM1448 has the effects of relieving bone calcium loss, maintaining bone health, repairing bone injury, increasing osteoblasts and reducing osteoporosis degree.

The utility model discloses a proximal femur intramedullary nail main nail guide needle entry point positioner, and relates to the technical field of medical instruments, in particular to a proximal femur intramedullary nail main nail guide needle entry point positioner which comprises a positioner body, the positioner body is composed of a handle portion and a low-incisura pressing portion, and the pressing portion is in a plate shape with a certain thickness. And the front edge of the piriform muscle nest is sensed through the side wall structure until the front edge and the piriform muscle nest are relatively clamped. Then, a guide needle is placed in a guide hole of the pressing part, and under C-arm machine perspective, the position of the guide needle on the side position X-ray perspective piece is properly adjusted, so that the needle inlet point of the guide needle is located at the vertex position on the normal position X-ray perspective piece and located at the central axis position of the femoral neck on the side position X-ray perspective piece. The guide needle is inserted into the femoral shaft, the positioner is taken down, subsequent operation steps such as opening, imbedding of the main nail, the head nail and the tail nail are carried out in sequence, and the purpose of effectively and accurately locking the needle inserting point position of the main nail guide needle of the proximal femoral nail is achieved.

The invention provides an orthopaedic implantation post-operation X-ray film simulation method and system based on a preoperative CT image, a medium, a program product and a terminal, and aims to accurately convert and present results of three-dimensional segmentation, key point identification and prosthesis positioning based on preoperative CT into a standard post-operation X-ray film simulation effect conforming to clinical routine. A doctor can intuitively and clearly foresee the form projection and the specific spatial position of selected prostheses including an acetabular cup, a lining, a ball head, a femoral stem and the like on a post-operation standard orthotopic X-ray film and the accurate relative anatomical relation between the prostheses and key bony markers of the pelvis and the femur in the pre-operation planning stage. By providing an intuitive and quantitative post-operation X-ray film simulation effect, a doctor is effectively assisted in selecting an optimal operation scheme and adjusting setting of parameters such as the size, the position and the angle of an implant, the predictability and the accuracy of operation planning are improved, and dependence on pure experience is reduced.

An apparatus and method for inserting a femoral broach or femoral stem or acetabular cup into a bone. The apparatus includes at least one closed loop insertion mechanism to provide impacts on the associated handles of the broach, stem, or the acetabular cup; at least one sensor to sense a series of impacts, including impact angle, and to provide real-time feedback of the alignment and / or condition of the bone; and a processor operably connected to the at least one sensor. The processor includes an algorithm that receives the real-time feedback to control the force, frequency, and alignment of the impacts by the at least one closed loop insertion mechanism.

Bone and joint surface reconstruction methods are disclosed for the therapeutic amelioration of joint defects caused by various conditions, injuries, and diseases to help eliminate or reduce pain and return the joint to its proper bio-mechanical function without the need to replace fully or partially the anatomical joint. The joint may specifically include mammalian joints such as the femorotibial joint, for example. The methods disclosed herein leverage the significant role the subchondral bone plays in the health status of the afflicted joint.

The present application relates to femoral stem prosthesis, specifically provides a femoral stem prosthesis with twisted trabecular structure, aims to solve the problem that although the existing femoral stem prosthesis has trabecular porous structure to promote bone growth, but still due to the high material elastic modulus and stress concentration inside the pore, leading to stress shielding effect and trabecular fracture, so it is difficult to effectively prevent long-term loosening of the prosthesis. For this purpose, a femoral stem prosthesis with twisted trabecular structure of the present application comprises a trabecular structure unit arranged on the surface layer of the prosthesis, the shape of the trabecular structure unit is a space net structure, the space net structure is provided with pores, the pores can accommodate new bone, and the space net structure is twisted from the inside of the prosthesis to the surface layer of the prosthesis. The present application introduces the mechanical regulation effect brought by structure twisting by arranging the space net trabecular structure which is twisted continuously from inside to outside on the surface layer of the prosthesis, on the basis of ensuring that the pores can be used for new bone growth and realizing bone-prosthesis biological fixation.

To provide a sleeve for a prosthetic implant having an anatomical profile.SOLUTION: The invention relates to: a sleeve (10) for a prosthetic implant (100) implantable in bone such as a femur; and related modular prosthetic assembly (200) including at least a rod (110), an intermediate neck component (112) and a sleeve (10).SELECTED DRAWING: Figure 1

A device for forcefully inserting a surgical implant in a recipient bone by impaction, comprising an impactor (10) that exerts an impaction force on the implant and is associated with at least one sensor (12). The sensor (12) measures a value from among the exerted impaction force and the deformation of the impactor (10) and provides a measurement signal representing the temporal variation of said value during an impact. The sensor (12) is connected to a processing unit (30) that is configured to compute, on the basis of the temporal variation of said value during the impact, an indicator representing the level of contact between the implant and the recipient bone. The indicator corresponds to the duration separating the instant corresponding to the first maximum amplitude peak of the measurement signal from the instant corresponding to the second maximum amplitude peak of the measurement signal. The implant can be a femoral rod (2).

The present invention provides a proximal femoral cancellous bone harvesting and implanting device, belonging to the field of medical device technology. The device comprises a femoral head X and a cancellous bone harvesting region Y at the distal end of the femoral head. The device comprises an outer tube, the outer tube comprising a lower sleeve and an upper sleeve, a connecting mechanism being provided between the lower sleeve and the upper sleeve, the connecting mechanism enabling an adjustable angle between the lower sleeve and the upper sleeve, the central axis of the lower sleeve being arranged along the bone harvesting region Y toward the femoral head X, the lower sleeve being implanted into the femoral body to establish a bone harvesting and implanting channel, the lower sleeve, the upper sleeve, the inner tube, and the connecting mechanism being provided in the present invention cooperating with each other to achieve bone harvesting and implanting operations, eliminating the need to replace instruments during the bone harvesting and implanting processes, and facilitating operation. Specifically, the inner tube can be simultaneously passed through the upper sleeve and the socket member to reach the bone harvesting region Y for bone harvesting, or the inner tube can be simultaneously passed through the lower sleeve and the upper sleeve to reach the interior of the femoral head X for bone implanting.