The invention discloses a bionic gradient knee femoral prosthesis structure and a production method thereof. The prosthesis structure comprises a smooth curved-surface shell, a post-osteotomy completely-covering joint face, a gradient porous structure and a fixing device. The curved-surface shell is based on the shape of the distal end of a connate femur. The post-osteotomy completely-covering joint face reversely spreads to the distal-end curved surface of the connate femur. A solid more than 5mm distant from the curved surface is replaced by the gradient porous structure, and the fixing device is formed on the distal-end plane on the inner side of a femoral prosthesis. Compared with conventional standard prostheses, the prosthesis structure has the advantages that matching degree is high, and the prosthesis highly fits the bone shape of a connate knee and is adaptable to motions of a patient. The bionic gradient knee femoral prosthesis structure is easy to produce, and conventional production methods for conventional bionic gradient prostheses are complex; by the 3D (three-dimensional)-printing production method, prostheses can be customized according to individual differences of patients, production period is short, cost is low, and a possibility for application and development of individualized therapy is provided.