406 results about "Skeletal bone" patented technology

A sacroiliac (SI) joint implant assembly addresses SI joint dysfunction and degenerative sacroiliitis. The assembly includes a first implant body, a second implant body, and a piezoelectric layer positioned between them. The piezoelectric layer generates electrical charges when subjected to mechanical stress, stimulating bone growth and enhancing stability of the SI joint after surgery. The implant bodies may feature non-planar surfaces to distribute compressive and shear forces unevenly across the piezoelectric layer. The assembly can be secured using fasteners such as screws, pins, or brackets, and may include porous or fenestrated bodies made from materials like titanium or polymers. Some implant assemblies are designed for minimally invasive surgical procedures, with configurations that allow for precise placement using guide wires and imaging techniques. The assembly aims to stabilize the SI joint and promote bone fusion, leveraging the piezoelectric effect to improve the overall efficacy of the fusion procedure.

An example apparatus is provided for the approximation of two bones. The apparatus can include a first anchor configured for insertion into a first bone. The apparatus can include a flexible segment, and an internal mechanism configured to adjust a distance between the first bone and a second bone. The internal mechanism can include first and second components, the first component configured to engage with a distal end of the flexible segment, and the second component configured to engage with the first component and the first anchor such that the second component is movable along a length of the first anchor to cause the first component to move thereby adjusting the distance. The apparatus can include a second anchor configured to engage with the second bone and the flexible segment such that the flexible segment extends between the first component of the internal mechanism and the second anchor.

The utility model relates to medical equipment technical field, concretely relates to a kind of distal end front lateral tibia locking steel plate, including distal end steel plate section, connecting portion and proximal end steel plate section being sequentially connected, the connecting portion is from the distal end steel plate section to the proximal end steel plate section setting, uses, the locking position of extension locking steel plate can be adjusted by extension locking component, i.

The present invention provides an osteosynthesis plate for fixing bone fragments in the repair of bone, particularly the mandible. [Solution] The plate body P comprises a plate body having at least one bridge portion BU used to bridge a gap S extending between bone fragments K1, the plate body comprising fixing portions BA1, BA2 each associated with at least one fixing point, at least one fixing point BP1, BP2 of the fixing portions formed on an island portion IA, the island portion being connected to each associated fixing portion only via spring segments FS1, FS2 which allow elastically restorable relative displacement between each fixing portion and each island portion, at least one of the spring segments causing relative displacement between the island portion and the associated fixing portion when a load is applied in the principal loading direction of the bone, and increasing the distance between the island portion and at least one bridge portion.

A method for providing a bending mold for an off-the-shelf implant, the method comprising obtaining information about a bony anatomy of a patient from one or more medical images; developing a virtual three-dimensional model of the bony anatomy based on the information about the bony anatomy, selecting an off-the-shelf implant, simulating a bending of the off-the-shelf implant using a three-dimensional model of the selected off-the-shelf implant and the virtual three-dimensional model of the bony anatomy to obtain a virtually bent implant having a first, bone-facing, surface and a second surface opposite the first surface, using the virtually bent implant, designing a bending mold mating with the first or the second surface, and based on the design of the bending mold, manufacturing the bending mold using additive manufacturing.

The application discloses a functional composition for improving bone and joint health, a conditioner and application. The functional composition comprises a first active component and a second active component; the first active component comprises elastin peptide, haematococcus pluvialis and ergothioneine; and the second active component comprises one or more of houttuynia cordata and non-denatured type II collagen. The application realizes the protection effect on joint, cartilage and bone health by scientific matching of the components and synergistically improving the glycosaminoglycan level in chondrocytes and the osteocalcin level in osteoblasts. Meanwhile, the components in the functional composition for improving bone and joint health are natural and have good biocompatibility, and have no obvious side effects, so that the application provides a kind of drug or a substitute for the treatment and prevention of bone diseases.

The present invention aims to provide a technology that can more easily and accurately determine the posture of bones of characters that virtually represent humans, etc. in a virtual space, or robots, etc. existing in a real space. In a skeletal model in which a parent bone and a child bone are connected by a joint, the posture determination method of the present invention, which determines the posture of a child bone using a plurality of parameters defining the rotation of the child bone relative to the parent bone, comprises the steps of making a judgment on at least one of the plurality of parameters, correcting the plurality of parameters based on the judgment result, and determining the posture of the child bone using the corrected plurality of parameters. The step of making a judgment includes making a first judgment on whether any one of the plurality of parameters exceeds a first limit, wherein the first limit is expressed as a limit in which at least one parameter affects a limit related to two or more other parameters. The step of correcting the plurality of parameters includes, if the first judgment result determines that the first limit has been exceeded, a step of correcting the plurality of parameters using the first limit so that the plurality of parameters are within the range of the first limit.

A surgical stapler that can deliver staples or anchors into both tendon and bone. The staples or anchors releasably engage to the end of a staple rod. The stapler rod includes a butterfly clip on its proximal end, the butterfly clip having two wings or panels and a striking surface between the wings. The stapler is used to secure a biological construct to tendon or bone during arthroscopic surgery. The device includes a stapler handle with an insertable staple rod. The stapler handle drives the staple rod to advance a staple into the bone or tendon.

The application discloses a preparation method of egg yolk phospholipid polypeptide which is helpful for bone growth and improvement of brain health, and comprises the following steps: (1) raw material pretreatment to obtain a reaction substrate solution; (2) primary enzymolysis to prepare a primary enzymolysis solution; (3) secondary enzymolysis to prepare a secondary enzymolysis solution; (4) inactivation, the temperature of the secondary enzymolysis solution prepared in the step (3) is adjusted to 85-95 DEG C, and the enzyme is completely inactivated by keeping for 10-15 min; (5) fermentation; (6) post-treatment, the fermentation liquid after the fermentation is kept at 50-60 DEG C for 10-30 min, and then cooling, centrifugation, collection of supernatant, vacuum freeze drying or spray drying of the supernatant are carried out, so that the egg yolk phospholipid polypeptide powder is obtained. The natural compound rich in specific functional peptide segments and phospholipids is prepared through the two-step enzymolysis coupling fermentation process, can effectively promote the growth and development of the bone, significantly improve the learning, memory and cognitive ability, and can significantly promote the proliferation of osteoblasts.

This application discloses a training method, apparatus, device, and storage medium for a joint angle prediction model, relating to the field of computer technology. The method includes: acquiring training sample data, which includes skeletal parameters, sample wrist joint pose sequences, and arm angle labels for the sample wrist joint pose sequences; obtaining arm angle feature information based on the sample wrist joint pose sequences using a selective state-space network of the joint angle prediction model to be trained; obtaining elbow position prediction information based on the arm angle feature information and skeletal parameters using a differentiable kinematic layer of the joint angle prediction model to be trained; and iteratively updating and training the joint angle prediction model to be trained based on a preset objective function, the training sample data, the arm angle feature information, and the elbow position prediction information to obtain a trained joint angle prediction model.

A method for attaching tissue to bone includes the steps of inserting a first anchor into bone, advancing a first limb of a first suture from the first anchor through the tissue and a scaffold, and advancing a second limb of the first suture from the first anchor though the tissue. Alternate methods for attaching tissue to bone are also disclosed.

The application discloses a bone age prediction method and system based on a multi-modal large model and a computer readable storage medium, belongs to the technical field of artificial intelligence and medical image processing, and comprises the following steps: fusing a left-hand DR image and clinical indexes through an end-to-end mode, constructing a multi-modal large model fine-tuned according to a bone age field, and outputting image-observed description of each bone in a left-hand wrist and bone-by-bone structured results of maturity levels; calculating a total bone age value through a scoring rule of a bone age evaluation standard, and generating and outputting a bone age evaluation report containing the bone-by-bone image-observed description, the maturity levels and the total bone age value. The application solves the problems of insufficient utilization of clinical indexes, heavy report writing burden, easy hallucination of model output and insufficient compliance of bone age calculation in the prior art, improves the accuracy of bone age prediction, clinical compliance and evaluation efficiency, and can be widely applied to hospitals, primary medical institutions and children growth and development screening scenes.

Methods are provided for aesthetic restoration and reconstruction of bone loss, deficit, defect, or a combination thereof. The methods include administration of one or more suitable bone derived compositions by a minimally invasive procedure such as injection using a needle, syringe, etc., placement in or through a small incision, or a combination thereof. The properties and characteristics of the bone derived composition, including without limitation, flowability, injectability, size, shape, and physical form, are limited only by the requirement that they are capable of administration by a minimally invasive technique. For example, these methods are effective for restoration of facial features, e.g., lost chin definition, jawline definition, bone around nasal lines, and bone around the upper and lower eye area. These methods are also effective for treatment of bone deficiency and loss in other body features such as shoulders and collarbones, pelvis, feet, ankles, hands, and wrists.

This invention discloses a deep learning-based method for predicting orthodontic outcomes, belonging to the field of artificial intelligence-assisted technology. The method includes acquiring multimodal initial data of the target patient, comprising craniofacial CBCT 3D images, intraoral 3D scan models, and a digital design scheme for orthodontic appliances containing target tooth displacement data. Based on the CBCT 3D images, macroscopic geometric features of the jawbone are extracted using a macroscopic morphological encoder, and microscopic tissue features of the periodontal region are extracted using a microscopic tissue feature encoder. The macroscopic morphological encoder is a 3D convolutional neural network, and the microscopic tissue feature encoder is a local window attention network based on a visual Transformer. This invention can predict the dynamic effects of the interaction between tooth movement and adaptive skeletal remodeling, and is particularly suitable for predicting orthodontic outcomes in adolescents during their growth and development period, addressing the industry pain point of large systematic biases in static models in such scenarios.

A toggle-type suture anchor that incorporates individual suture tensioning and locking without knot tying. The anchor includes several exemplary designs of toggle bodies having a working suture pre-threaded through one or more passages therethrough. A locking suture loop is pre-threaded relative to the working suture and includes a collapsible loop that encircles a portion of the length of suture running longitudinally adjacent the side of the anchor. With the loop open, the working suture can slide through the anchor, however, when the loop is closed the working suture is locked in position to retain tension on the working suture. Alternatively, the locking suture loop can be replaced with a mechanical locking member that moves from a first unlocked to a second locked position. The exemplary anchors can be utilized in a pre-strung connected array of anchors.

To provide a deboning and butchering tool that can efficiently and easily remove the scapula from the processed meat after it has been divided during meat processing. [Solution] The bone removal and dismantling tool has a stem rod portion that extends in a straight line, a claw portion formed at one end of the stem rod portion, and a bone-holding portion that extends in a winding manner from the side to the front, starting from one side of the stem rod portion, and is characterized in that the tip of the bone-holding portion is positioned to cross and extend beyond the front of the stem rod portion.

Embodiments of the disclosure include methods and compositions related to modulation of bone using particular fibroblasts. The modulation includes reducing osteoclast activity and / or activation and / or stimulating osteoblast activity. In particular cases, bone is modulated in an individual with a bone condition, such as osteoporosis. Particular fibroblasts may be delivered to reduce inflammatory cytokine production including RANK ligand.

The present invention provides a system and method for a two-step registration procedure that enables complete surgical intervention by a robot. [Solution] A system for intraoperative navigation is provided, comprising a processing unit and a tracking device for real-time or near-real-time tracking of an object in a 3D coordinate system, wherein the processing unit is configured to receive an X-ray image depicting an anatomical structure including at least one bone, and to determine an incomplete registration of the position of the anatomical structure in the 3D coordinate system. The incomplete registration is determined based on a 3D dataset of the received anatomical structure and a plurality of virtual X-ray images generated from different directions based on the 3D dataset of the anatomical structure. The incomplete registration can be understood as an approximation of the position of the anatomical structure. Based on the incomplete registration, instructions for the navigation of the device are provided.

This invention provides a wireless, passive force-position implantable growth monitoring system and its fabrication method for early-onset scoliosis correction. The system includes: a connected compressible capacitive sensor and a flexible wireless antenna coil; the compressible capacitive sensor is connected to a self-growing early-onset scoliosis correction implant growth rod, and the flexible wireless antenna coil is disposed within the body. The compressible capacitive sensor and the flexible wireless antenna coil together constitute an LCR resonant circuit; the compressible capacitive sensor monitors the pressure changes caused by the elongation of the self-growing early-onset scoliosis correction implant growth rod during tissue or bone growth, thereby causing changes in capacitance and resulting in changes in the resonant frequency of the LCR resonant circuit; the resonant frequency change is detected and read out wirelessly via an external readout device. This system is designed to meet the needs of digital rehabilitation, requires no internal power supply, and has a stable structure, making it suitable for growth monitoring after early-onset scoliosis correction surgery.

This application discloses a method and its application for preparing collagen peptides by stepwise enzymatic hydrolysis with dynamic pH control, belonging to the field of protein preparation technology. The method includes raw material pretreatment, stepwise enzymatic hydrolysis with dynamic pH control, and post-treatment to obtain collagen peptide products with a molecular weight distribution of 800-2000 Da. The obtained products can be used to prepare products with bone growth promotion functions. This application employs a combined process of stepwise enzymatic hydrolysis with dynamic pH control, alkali-thermal coupling pretreatment, and 2000 Da retention. The steps work synergistically: alkali-thermal treatment exposes enzyme cleavage sites, dynamic pH control enables efficient enzymatic hydrolysis, and 2000 Da retention of active components results in a significantly higher yield and content of collagen peptides compared to conventional processes. Animal experiments have demonstrated that the collagen peptides have bone growth promotion activity, and the mechanism of action has been revealed at the IGF-1 signaling pathway level.

The application relates to the technical field of digital human body models, in particular to a digital human body muscle model posture generation method and device. The method comprises the following steps: obtaining a tomographic image of an initial posture of a human body by using high-precision CT, and inversely modeling a geometric model of human body bones and muscles according to the tomographic image; calculating a first motion influence weight of each muscle node attached to a bone node according to each muscle node and the bone node; calculating a second motion influence weight of each muscle node according to the influence of adjacent muscle nodes on each muscle node; calculating a comprehensive weight of each muscle node according to the first motion influence weight and the second motion influence weight; and calculating a Laplace coordinate of a next moment of a current muscle node according to the comprehensive weight of the current muscle node, the position of the current muscle node and adjacent muscle nodes. The application generates a high-fidelity muscle geometric model by using a Laplace mesh deformation constraint technology.

This specification provides a method, apparatus, device, medium, and program product for rendering flexible objects. The method includes: acquiring reference pose information for each bone point in the skeletal chain of the flexible object, wherein the constraint pose information of the endpoint bones is determined based on the pose of the connected objects of the endpoint bones; determining endpoint pose information based on the reference pose information of each endpoint bone; performing physical simulation based on the reference pose information of intermediate bones to obtain intermediate pose information, wherein the intermediate bones are bone points located between the endpoint bones; and rendering the flexible object based on the endpoint pose information of each endpoint bone and the intermediate pose information of the intermediate bones. This solution differentiates the processing of endpoints and intermediate bones, balancing precise control with physical realism, achieving accurate and natural flexible simulation. It can be widely applied to digital cultural products in the next-generation information technology fields such as games and virtual reality.

A computer-implemented method is provided. The computer-implemented method generates a milling path for a tool of a surgical system, the milling path designed to enable the tool to resect material from a bone, the method including obtaining a model of the bone, intersecting an allowed volume with the model to define a resection volume intended to be removed from the bone, and generating a plurality of cross sections. The method further includes, for a cross section, identifying a sub-volume of the resection volume corresponding to the cross section, generating a milling path segment designed to enable the tool to remove the sub-volume of the resection volume, for the sub-volume of the resection volume, identifying a region to be avoided by the tool, generating a transition path segment designed to avoid the region, and generating the milling path by combining the milling path segment and the transition path segment.

This invention relates to the interdisciplinary field of image recognition and intelligent medical technology, specifically disclosing a method for orthopedic rehabilitation movement recognition and assessment based on image recognition. This method acquires patient motion images using a non-invasive multi-view visual sensor, extracts the three-dimensional coordinates of key skeletal points, and constructs a parametric biomechanical digital twin model integrating joint range of motion, muscle force lines, and ligament tension mechanisms. The key point data is input into a graph neural network for posture recognition, and the digital twin model is simultaneously invoked for physical feasibility verification and posture correction. Finally, the spatiotemporal trajectory similarity is calculated using a standard rehabilitation movement template, generating a comprehensive assessment result including movement completion, safety level, and injury risk. This invention, through the above technical solution, improves the robustness, physiological rationality, and clinical safety of movement recognition.

This invention discloses a method for in-situ preparation of calcium chelate peptides that promote intestinal calcium absorption and osteoblast development from fish scales using high-pressure homogenization-assisted enzymatic hydrolysis. The method uses fish scales as raw material, which are pulverized and then pretreated with high-pressure homogenization to break down the dense cross-linked structure of the scales. Pepsin is used as the hydrolytic enzyme to achieve efficient enzymatic hydrolysis of collagen and in-situ chelation with natural calcium, resulting in a one-step preparation of collagen calcium chelate peptides. The product has a calcium retention rate of ≥84.16%, is rich in affinity amino acids, and shows a ≥62.97% increase in calcium transport compared to calcium chloride in a small intestinal epithelial cell absorption and transport model, while being safe and non-cytotoxic. This invention is a green and efficient process that eliminates the need for decalcification steps, achieving a collagen calcium chelate peptide yield of ≥83.4%. It realizes the high-value utilization of aquatic by-products and can be directly applied to various calcium supplements such as food and health products that enhance intestinal calcium absorption and promote bone development, solving problems such as low bioavailability of traditional calcium preparations and severe calcium loss in existing fish scale utilization processes.