The invention belongs to the field of
biology, particularly relates to a preparation method, a composition and application of yak
bone collagen hydrolysate capable of preventing and treating
osteoporosis, and further provides an oral
liquid composition which comprises the following raw materials in percentage by
mass: 6% of yak
bone collagen hydrolysate, 2% of
glucosamine sulfate, 0.4% of
chondroitin sulfate and the balance of water. The yak
bone collagen hydrolysate and oral
liquid composition prepared by the method can improve
pathological changes of bone tissues of mice with
osteoporosis, promote regeneration of collagen in
osteoporosis tissues, improve BMD, BV / TV, Tb.N and Tb.Th of cortical bones, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, improve osteoporosis, and improve osteoporosis. The Tb.Sp and Po of cortical bones are reduced, and the excellent function of preventing and treating osteoporosis is achieved.