165 results about "Bone Cortex" patented technology

The invention provides a cortical bone screw automatic planning method and device based on a statistical morphology model. The method comprises the following steps: acquiring CT image data of any object; based on the CT image data, segmenting point cloud information of a vertebral body to be subjected to screw placement; acquiring a statistical shape model and cortical bone screw planning information corresponding to the serial number; and registering the statistical shape model to the point cloud information, and determining a cortical bone screw plan of the vertebral body to be subjected to screw placement. In the application, the preset screw placement planning of the cortical bone screw is performed through the statistical shape model, and the preset screw placement planning is mapped to the current spinal column three-dimensional model through registration, so that the preset screw placement planning only needs to be performed on the statistical shape model, and a screw placement model is not needed, thereby solving the problem that a large number of cases need to be collected to realize the screw placement model; therefore, the problem of nail placement of the cortical bone can be solved.

Computer implemented methods, systems, and computer products employing program code or algorithms for use in customized patient specific hip implants or femoral stems or sleeves having an outer surface that corresponds more closely to the inner surface of the cortical bone of a patient's femur compared to conventional hip implant or femoral stems or sleeves based on population-based design.

The invention discloses a bone scaffold fusion design and preparation method based on mirror image registration, and the method comprises the steps: firstly, based on a three-dimensional medical image of a femoral defect region of a patient, combining an opposite-side complete femoral CT image, and achieving the automatic recognition and complementation of the defect region through the mirror image transformation and ICP registration technology; after defect boundary extraction is completed, three-dimensional reconstruction is carried out on the individualized outer contour of the left bone tissue, and an STL format model is exported. According to the femur functional partition characteristics, a Diamond structure is adopted in a cortical bone area to enhance mechanical support, and a Gyandroid structure is selected in a cancellous bone area to achieve porosity gradient filling, so that the permeability is optimized, and cell proliferation is promoted. Continuous transition among the structures is realized through a Sigmoid function, and the stability and the biological adaptability of the whole structure are improved. And finally, the stent model is subjected to selective laser melting, and a Zn-3Mg alloy material is utilized to complete printing manufacturing.

The utility model discloses a 3D printing porous pedicle screw which comprises a screw body part and a screw cap part, the screw body part comprises a cortical bone thread area close to one end of the screw cap part and a cancellous bone thread area far away from one end of the screw cap part, and a porous structure area is arranged at one end, not connected with the screw cap part, of the screw body part. The porous structure area comprises an inner core column extending in the axial direction of the nail body part, at least one reinforcing beam and a porous structure, the reinforcing beams extend outwards from the periphery of the inner core column, and the porous structure is annularly distributed on the outer periphery of the inner core column. The porous structure can efficiently induce bone tissue to grow in, the screw and a vertebral body are connected into a whole, stress is effectively dispersed, the stability of the screw is improved, the porous structure is arranged on the vertebral body at the front end of the screw, screw breakage caused by stress concentration of the screw in a vertebral pedicle area can be avoided, meanwhile, the stability of the screw can be better improved through the reinforcing beam, and the service life of the screw is prolonged. The possibility of fracture of a porous area of the screw is reduced, generalization performance is better, and the use experience feeling is improved.

The embodiment of the invention provides an intelligent bone drilling self-adaptive control method for a mechanical arm, which comprises the following steps: acquiring displacement deviation of the tail end of a drill bit of an orthopedic surgical robot, obtaining an error change rate through differential calculation, and combining a bone layer type as an input variable of a fuzzy controller and a feeding speed as an output variable; input variables are fuzzified through a membership function, and a fuzzy language variable set is obtained; according to the set and a preset rule base, constructing a multi-rule group structure comprising three types of scenes of free space, cancellous bone and cortical bone, and setting corresponding fuzzy rule subsets for different bone layers; designing a ''minimum-maximum'' rule activation and combination strategy for reasoning by adopting a Mamdani type fuzzy reasoning method according to fuzzification input and a multi-rule group structure, and generating a fuzzification output variable set; and defuzzification is performed through a gravity center method to obtain a continuous speed instruction, and dynamic regulation and control of the drill bit feeding speed are achieved. When approaching a penetration point, the device automatically decelerates and safely stops, so that the safety and accuracy of an operation are effectively guaranteed, and over-drilling injury is prevented.

Surgical systems and methods for manipulation of an anatomy that includes cortical and cancellous bone. A surgical manipulator has a robotic arm to move an instrument with an energy applicator. A sensor senses forces / torques applied to the energy applicator. Controller(s) obtain a tool path for the energy applicator to traverse. A segment of the tool path transitions into, or between, cortical bone and cancellous bone. The controller(s) control the manipulator to advance the energy applicator along the tool path according to a first feed rate to manipulate the cortical or cancellous bone and detect, with the sensor, a change in the forces / torques being indicative of the transition. In response to detection of this change, the controller(s) control the manipulator to advance the energy applicator along the tool path according to a second feed rate, greater / less than the first feed rate.

The invention provides a gradient density metal implant additive manufacturing method, and relates to the technical field of selective laser melting additive manufacturing, according to the method, continuous gradient density distribution of a metal implant from an outer layer to an inner layer is achieved through multi-mode sensor fusion and a self-adaptive control algorithm, biomechanical characteristics of a skeleton are accurately simulated, and the manufacturing precision of the metal implant is improved. The step of designing a porous structure is omitted; cortical bone (high density) and cancellous bone (porous) structures of human bones can be accurately simulated, and the biomechanical suitability of the implant is improved.

The invention relates to a spine bone structure and bone mineral density automatic measurement method based on a CT image. The method comprises the following steps: performing CT scanning on a phantom with known bone mineral density to obtain a real bone mineral density calculation formula; all CT images in the DICOM format are read, DICOM analysis is carried out, and three-dimensional CT value data and other main information of all the images are obtained; performing outer contour segmentation on the whole spine in the CT image by using a deep learning network to obtain an outer contour of each vertebral body in the image; the method comprises the following steps: carrying out preliminary segmentation on cortical bones and cancellous bones by adopting a dynamic threshold method aiming at each vertebral body, selecting a preliminarily segmented cancellous bone region, using a maximum connected domain algorithm in a three-dimensional direction, retaining a maximum connected region, and further measuring the bone mineral density, namely calculating overall topology parameters, the bone mineral density and the bone mineral content of the current vertebral body; calculating the rubbing parameters, the bone mineral density and the bone mineral content of the current vertebral cortical bone and cancellous bone; and measuring the content of the cross section of the cone.

The application discloses a kind of three-dimensional CBCT skull image fine granularity segmentation method and system.The present application includes the following steps: first, construct first training dataset;Then, in combination with first training dataset, after training secondary segmentation neural network model, obtain trained secondary segmentation neural network model;Then, using trained secondary segmentation neural network model to the three-dimensional CBCT skull image to be processed is segmented, and the segmentation result of each structure of skull is obtained;Finally, using the improved region growing method is carried out the segmentation of the bone cortex and bone marrow of upper and lower jaw bones, and the bone cortex and bone marrow segmentation result corresponding to upper and lower jaw bones is obtained, so as to complete the fine granularity segmentation of three-dimensional CBCT skull image.The method proposed in the present application can separate the fine granularity region of oral and maxillofacial region, including complete skull, upper and lower jaw bones, teeth, bone cortex, bone marrow, nerve canal, maxillary sinus, incisor canal and other structures.

An osteogenic composition comprises growth-factor augmented cortical bone and cancellous bone having viable endogenous osteogenic cells that remain adherent to the cancellous bone. The growth-factor augmented cortical bone comprises demineralized cortical bone amplified with growth factors derived from a demineralized bone, and the cancellous bone not having been subjected to a loosening agent. The osteogenic composition is cryopreserved or lyopreserved. A method for preparing an enhanced graft composition with improved osteoinductive properties includes processing demineralized cortical bone; solubilizing growth factors from demineralized bone; and mixing the demineralized cortical bone with the solubilized growth factors.

This invention pertains to spinal pedicle screws, specifically locking spinal pedicle screws, including perforated pedicle screws and cortical bone screws that work with them. The proximal end of the self-locking master screw is thickened. A through-hole is provided in the thickened section of the pedicle screw, and the cortical bone screw is driven into the through-hole and fixed to the upper and lower cortical bone layers of the pedicle to form a triangular fixation. After the pedicle screw is implanted, both ends of the through-hole of the pedicle screw are located inside the pedicle. A hole is drilled from the posterolateral aspect of the pedicle using a special aiming device, passing forward and upward through the oblique hole of the pedicle screw, and then through the anterior and superior cortical bone of the pedicle. After measuring the length, a suitable cortical bone screw is selected, screwed in, and locked, fixing the posterolateral cortical bone, the pedicle screw, and the anterior and superior cortical bone of the pedicle. The screw is positioned in a safe area of ​​the superior cortical bone of the pedicle. The cortical bone screw is fixed to the upper and lower cortical bone of the pedicle by passing through the oblique hole, thus locking the position of the pedicle screw.

The invention discloses an infectious bone defect bionic repair hydrogel stent and a preparation method and application thereof, and is characterized in that the infectious bone defect bionic repair hydrogel stent is composed of an upper antibacterial-vascularization layer simulating a periosteum structure, a middle support layer simulating a bone cortex structure and a lower regeneration-regulation layer simulating a cancellous bone structure; the upper antibacterial-vascularization layer is prepared from photoresponse CuxO / SiC heterojunction powder, the middle support layer is prepared from silk fibroin, and the lower regeneration-regulation layer is prepared from HAP (at) Cur-CNDs-Pt NPs composite nanoparticles. The multi-dimensional structure and function integration realizes the full-period regulation and control of antibiosis-barrier-regeneration, breaks through the limitation of the traditional single-function stent, and provides an integrated solution for infectious bone defect repair.

The invention discloses a bone-like osteoma microwave ablation thermal injury assessment method based on all-optical parameters, which comprises the following steps: respectively considering thermal injury models of cortical bone and cancellous bone under different microwave ablation conditions by constructing a simulation model conforming to bone tissue characteristics; according to the method, construction of an incomplete P5 approximation model is proposed, bone tissue all-optical parameter anti-construction research based on steady-state radiance is carried out, the accuracy is high, calculation is convenient, temperature parameters and biological tissue all-optical parameters are analyzed in a combined mode, a tissue thermal damage model of the temperature and tissue all-optical parameters is established through theoretical research, and due to the characteristics of different bone tissues, the tissue thermal damage model can be used as a tissue thermal damage model of the temperature and tissue all-optical parameters. The tissue types are considered in the thermal damage model, and effective bone tissue thermal damage factors are designed based on different tissues, so that the evaluation accuracy is ensured.

The utility model provides a femoral stem, and relates to the field of passive medical instruments. Comprising a femoral stem conical part, a femoral stem neck part, a femoral stem shoulder part and a stem body, one end of the femoral stem neck part is connected with the stem body through the femoral stem shoulder part, and the other end of the femoral stem neck part is connected with the femoral stem conical part; at least two first protrusions are evenly arranged on the handle body and around the circumference of the handle body, the length of the first protrusions is equal to that of the handle body, and a second protrusion is arranged between every two adjacent first protrusions. The femoral stem can adapt to marrow cavities of different shapes and sizes, and can better adapt to anatomical features of cortical bones and thighbones of the marrow cavities of patients.

CT images from the neck, lung, cardiac, abdominal, pelvis, hip, spine or lower extremity areas are obtained and analyzed by a computer to measure trabecular bone density on each level it is available, in the spine and hip. Any bone tissue associated with vertebrae that is fractured is excluded, along with Schmorl's nodes, large blood vessels, and cortical bone, to accurately average the trabecular bone density on a scan. The density of fat, heart, and muscle tissue of a subject is used to calibrate the results. That data may be input to an absolute fracture risk model (Fracture Risk Algorithm calculator). Information such as bone density, T score, Z score, fracture risk, and identification of vertebral fractures (if present) may be determined and reported.

Methods, hydrogel compositions, and apparatuses (e.g., implants) that address the need for preventing subsidence of implants through cortical bone layers and exposure of hydrogel compositions to bone and other degradatory interfaces, by securing hydrogel compositions to and within implant structures via a crimping process.

Disclosed herein are tracking element fixation elements for affixing computer-assisted surgical system (CASS) tracking elements to a patient. Fixation systems provide kinematic coupling or clamping functionality that allows tracking elements (attached to a tracker arm) to be repeatedly and accurately detached and re-attached to facilitate removal when necessary, such as for point probe data collection, during impaction, bone movement, and / or the like. Fixation systems may include a baseplate and a tracker arm configured to be kinematically coupled to the baseplate via a magnet associated with independent ball bearings or contacts extending from a bottom surface of the magnet. The ball bearings or contacts are configured to be received within corresponding grooves of the baseplate. The baseplate may include one or more protrusions extending from a bottom of the baseplate that are configured to be impacted into the cortical bone of the patient.

The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment non-soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of non-soft tissue (e.g. bone) when combined with a biocompatible matrix, preferably SIS. The invention further provides methods of using compositions comprising muscle-derived progenitor cells with a biocompatible matrix for the augmentation and bulking of mammalian, including human, bone tissues in the treatment of various functional conditions, including osteoporosis, Paget's Disease, osteogenesis imperfecta, bone fracture, osteomalacia, decrease in bone trabecular strength, decrease in bone cortical strength and decrease in bone density with old age.

The present disclosure refers to a system for determining a cortical bone, comprising: an ultrasound transducer which is configured to transmit an ultrasound wave to a region of interest, and to receive a backscattered ultrasound wave which is backscattered from the region of interest, wherein the region of interest comprises a cortical bone; and an evaluation unit which is configured to determine at least one of a pore size, a bone thickness, and a speed of sound in the cortical bone by evaluating the backscattered ultrasound wave. Further, a method for determining a cortical bone is provided. A computer program product which, when executed by a processor, executes the method.

Provided is a skeleton protection method, which comprises administering to a subject in need thereof an effective amount of a peptide comprising the amino acid sequence of SEQ ID NO: 1. The present invention proves that administering the peptide of SEQ ID NO: 1 can ameliorate cortical bone erosion of calcaneus bone resulting from rheumatoid arthritis (RA) and restore the decline of RA-induced bone mineral density. Therefore, the peptide of SEQ ID NO: 1 possesses a therapeutic effect for skeleton protection.

Disclosed is a method for preferentially removing cartilage from a bone in a joint that is effective at removing the cartilage while minimizing any removal of the cortical bone.

The utility model relates to the technical field of orthopaedic minimally invasive surgery robots, and discloses a flexible mechanical arm for orthopaedic minimally invasive surgery, which comprises a base and a supporting seat, the top end of the base is fixedly connected with the supporting seat, and a first mounting groove is arranged in the supporting seat. According to the flexible mechanical arm for the minimally invasive surgery in the orthopedics department, during surgery, operation is conducted through a robot host after the mechanical arm is connected, surgery operation is conducted after a drill bit is correctly positioned, when the drill bit enters a vertebral pedicle to make contact with a first layer of cortical bone, vibration is strengthened, and when the drill bit breaks through the first layer of cortical bone, vibration is reduced; the flexible electron senses changes of vibration and pressure, the drill bit is stopped through an algorithm, and therefore the situation that the drill bit moves forwards excessively and causes iatrogenic injury is avoided, whether the drill bit is located at the optimal position or not can be sensed in real time in the operation process by setting the optimal pressure value and the optimal frequency value, and the operation efficiency is improved. The problem that operation guidance cannot be accurately conducted in the operation in real time is solved.

A method and system for analysis of medical images is presented in the field of analysis of medical images. The method and systems is provided to determine one or more parameters of bones in medical images. The method and system may be characterized as an advancement in analysis of medical images to ascertain bone health and discern pathologies in bone. Specifically, a system and method is disclosed for analysing medical images showing at least a portion of a bone to determine one or more bone parameters for the at least one portion of a bone. Steps taken by the system and method include: determining a region of interest of the medical image; identifying a boundary of at least one of an inner edge and an outer edge of cortical bone of the at least one portion of the bone within the region of interest; identifying at least one boundary of trabecular bone of the at least one portion of the bone within the region of interest; utilising the identified boundaries to determine at least one of the following bone parameters: orientation, bone mineral density, length, width of trabecular structure, for the at least one portion of bone within the region of interest.

An apparatus and methods are provided for a one-step dental implant that avoids pressure points and heat production within a patient's bone. The dental implant includes a bone cutting portion having a centering tip surrounded by bone cutting edges and soft tissue knives. The centering tip perforates the gingiva while the soft tissue knives dissect the gingiva with a precise circular cut. The bone cutting edges chisel the bone as the dental implant is tightened into the bone. Deflecting sides direct bone powder into axial bone storage areas. A gingival sealing portion includes a cylindrical portion that fits into cortical bone without friction or exerting pressure on the bone. The cylindrical portion removably retains components that include a silicone O-ring. Engaging sections of the cylindrical portion enable driving the dental implant into the patient's bone. Internal threads of the cylindrical portion enable clamping abutments onto the dental implant.

The embodiment of the disclosure relates to a computer tomography image-based acetabular cup prediction system and method, and relates to the technical field of medical image analysis, and the user information and the computer tomography image of a target user are acquired; the computer tomography image is subjected to image segmentation, and an acetabular region of interest is acquired; the corresponding Hounsfield unit value and the acetabular center coordinates of each pixel coordinate are acquired based on the acetabular region of interest, the screening area of the acetabular cup is determined based on the acetabular center coordinates and the received screening conditions, the Hounsfield unit value corresponding to each pixel coordinate is processed based on a preset dynamic threshold method, and the cortical bone Hounsfield unit average value and the cancellous bone Hounsfield unit average value of the screening area are obtained; prediction analysis is carried out based on the user information and the cortical bone Hounsfield unit average value and the cancellous bone Hounsfield unit average value of the screening area, and a prediction result is generated, so that more objective and accurate acetabular cup stability evaluation can be provided based on the prediction result.

The invention provides a bone evaluation method based on neural network enhancement and finite element analysis. The bone evaluation method comprises the following steps: acquiring an ultrahigh-resolution CT image of a living vertebra; performing domain conversion processing on the CT image by adopting a generative neural network; carrying out resampling and segmentation on the enhanced CT image; constructing a bone trabecula microstructure model in the cancellous bone mask area; assembling the RVE unit and the cortical bone model into a complete vertebral finite element model, and applying a multi-working-condition load to the RVE unit to calculate anisotropic material parameters; and carrying out axial compression finite element analysis on the complete centrum model, and judging the bone health state. According to the method, information of two dimensions of bone mass and bone, especially contribution of a bone trabecula microstructure to bone strength, is comprehensively considered, bone degeneration and fracture high-risk patients can be recognized earlier, and a scientific basis is provided for clinical early intervention.

Described herein are three-dimensional scaffold compositions and methods for bone repair or regeneration. In some embodiments, the disclosed scaffolds comprise a core portion mimicking a native trabecular bone structure that is surrounded by an exterior portion mimicking a native cortical bone structure. In some embodiments, the scaffolds may be functionalized by mineralization and / or pre-vascularization to promote bone and blood vessel formation.

An orthopedic surgical system includes a processor configured to receive preoperative 3D image data of a planned pedicle screw placement in a patient's vertebra; obtain intraoperative or postoperative 3D image data of a pedicle screw placement in the patient's vertebra; and determine an accuracy measurement of the pedicle screw placement in the patient's vertebra based on the preoperative 3D image data and the intraoperative or postoperative 3D image data. The accuracy measurement of the pedicle screw placement may be based on a distance from a pedicle screw to a cortical bone of a patient's vertebra or a distance from a pedicle screw to region of interest of the patient.

The application discloses a human variable cross-section bone thickness detection method and system based on ultrasonic guided waves, the system derives a human cortical bone dispersion curve through an anisotropic model, obtains an inverted cortical bone thickness distribution rule by using the dispersion curve, and further obtains a cortical bone two-dimensional thickness distribution image, and the system has no radiation hazard to patients, is low in cost, high in real-time performance, wide in application range, and convenient and fast in obtaining bone thickness measurement results, and takes into account the uneven human bone thickness distribution, and has important value in practice.

The present invention relates to a system and a method for bone fracture risk assessment and provides for a system to predict Osteoporosis and Osteopenia and its associated fracture risk automatically from conventional chest X-ray image. The invention provides an automated digital X-ray bilateral Clavicle Radiogrammetry and its estimation of Cortical Thickness and Calculation of Cortical bone mass indices of Clavicle to predict dual Hips (Neck) Bone Mineral Density (BMD), dual Hips (Total) Bone Mineral Density (BMD) and Spine (Total) Bone Mineral Density (BMD) as measured by dual energy X-ray absorptiometry (DXA) bone densitometer and 10-year probability of both Major Bones (hip, spine, humerus or forearm)—and Hip-Osteoporotic Fracture Risk Scores. Using the same chest X-ray, an automated prediction of Osteoporosis and Osteopenia at both dual hips and spine regions and 10-year probability of both Major Bones and Hip Osteoporotic Fracture Risk using Artificial Intelligence (AI).