24 results about "Therapeutic Procedure" patented technology

Described herein are therapeutic electrical muscle stimulation (EMS) apparatuses for the detection, diagnosis, treatment or prevention of a neurological disorder. These apparatuses (including EMS suits, user interfaces, and control systems, etc.) and methods may be used as part of a therapeutic or non-therapeutic procedure. For example, these methods and apparatuses may be part of an exercise or fitness and / or may be used as part of a therapy, such as in particular for physiotherapy and / or for treatment of a condition or a disease.

Systems and methods are provided for managing and reducing the severity or impact of a collision involving an apparatus secured to a table associated with a medical imaging and / or therapeutic gantry. Example systems are provided in which an apparatus is secured to the table such that a distal region of the apparatus extends beyond a longitudinal end of the table. A pivot joint associated with the apparatus is provided such that when a collision between the distal region of the apparatus and an object occurs due to motion of the table, the resulting force causes the apparatus to rotate relative to the pivot joint, thus passively accommodating the applied force and preventing, or reducing the likelihood of, mechanical buckling of the apparatus in the presence of the force. In some example embodiments, the apparatus is configured to rotate and / or translate as a result of the force applied during the collision.

The invention discloses an execution mechanism, system and control method of a natural orifice passing diagnosis and treatment robot. The robot executing mechanism comprises a first continuous body section and a second continuous body section which are mechanically coupled, reversible anchoring components are arranged at the far ends of the first continuous body section and the second continuous body section respectively, and the first continuous body section has active controllable bending capacity. The robot system comprises the robot executing mechanism and a driving and control module. By controlling the two reversible anchoring parts to anchor alternately and coordinating and driving the two continuous body sections to push alternately and relatively, the robot executing mechanism can achieve growth type movement in the cavity. According to the control method, through the circulation steps of outer anchoring, inner bending extending, inner anchoring and outer follow-up, the robot executing mechanism gradually goes deep into the narrow bent cavity. An intracavity supporting point can be dynamically established through an alternate anchoring mechanism, and the advancing stability and operation precision of the flexible instrument are improved.

A method of marker-less registration of a pre-obtained medical imagery three-dimensional virtual model of a subject with live imagery of the same subject obtained prior to or during a surgical or therapeutic procedure performed on the subject, comprising: scanning the subject using a time-of-flight sensor to generate a point cloud data set corresponding to a skin layer of the subject, obtaining live imagery of the subject via a camera; receiving the pre-obtained medical imagery three-dimensional virtual model of a subject; processing the skin layer point cloud data set and the three-dimensional virtual model to determine one or more corresponding anatomical features of the subject present in both the point cloud data set and the three dimensional virtual model; aligning the point cloud data set and the three-dimensional virtual model in co-registration by aligning the determined one or more corresponding anatomical features of the subject in co-registration with each other; and displaying the three-dimensional virtual model so aligned within the live imagery of the subject.

The application provides a magnetic response composite hydrogel for integrated repair of bone defects and a preparation method thereof, and belongs to the technical field of medical materials. The composite hydrogel can efficiently inhibit tumor cell activity under the time sequence regulation of an external alternating magnetic field, and then provide a suitable microenvironment and key components for bone tissue regeneration, so that signal conversion and function connection from tumor killing to bone repair are realized. The material has good injectability and self-healing ability, can minimally invasively fill irregular defects, and has significant advantages in simplifying the clinical treatment procedure, shortening the treatment course, reducing the risk of tumor recurrence and improving the repair quality, and provides a new and integrated treatment strategy for tumor-related bone defects.

A tool to create virtual lesions inside a 3D lung tumor image. The image can be an MRI or CT image of a patient's lung to be treated. This virtual pre procedural ablation allows the operator to identify optimal ablation sites and select the optimal ablation parameters for the given anatomy. Also, the actual procedure will be performed with the lung parenchyma surrounding the tumor preventing ultrasound to penetrate beyond the tumor walls. A diagnostic mode will guide the operator to optimize ablation parameters. This virtual pre ablation, the parenchymal ultrasound barrier and the diagnostic catheter operation should enable the operator to conduct the therapeutic procedure safe, fast and effective.

Various example embodiments of the present disclosure provide systems and methods for the dynamic correction and reduction of thermal variations in skull-induced aberrations during a focused ultrasound therapy procedure. Unlike conventional approaches involving static corrections for skull-induced aberrations, various example embodiments of the present disclosure employ ultrasound detection and a skull thickness estimate from volumetric image data to intermittently and dynamically determine corrections for skull-induced aberrations, such that aberration correction reduction is updated intraoperatively and maintained despite local thermally-induced changes in the speed of sound of the local skull region due to intraoperative intracranial heating. Furthermore, in some example embodiments, a measure dependent on the speed of sound with the skull is intraoperatively determined and compared to a previously determined value of the measure to determine a change in the skull temperature, based on a pre-determined relationship between changes in the measure and changes in skull temperature.

The present invention relates to a medical interventional catheter, which includes a catheter body with both diagnostic and therapeutic capabilities. The catheter body includes a distal functional member configured for image-based monitoring of a tubular lumen of interest and for release of a therapeutic source to a target location in the tubular lumen of interest. The therapeutic source includes therapeutic energy and / or a therapeutic substance. This interventional catheter with both diagnostic and therapeutic capabilities provides real-time image-based monitoring in a therapeutic procedure, making the procedure more accurate and effective.

Systems and method for performing a therapeutic procedure including navigating a therapeutic device to target tissue, applying a first stimulus to the target tissue via a stimulus delivery element to contract the target tissue about the therapeutic device, and applying a first therapy to the target tissue contracted about the therapeutic device to denervate the target tissue.

A method of evaluating a vessel of a patient is provided. The method includes outputting, to a display device, a screen display including: a visualization based on pressure measurements obtained from a first instrument and a second instrument positioned within the vessel of the patient while the second instrument is moved longitudinally through the vessel and the first instrument remains stationary within the vessel; and a visual representation of a vessel; receiving a user input to modify the visualization to simulate a therapeutic procedure; and updating the screen display, in response to the user input, including modifying the visualization based on the user input. A system for evaluating a vessel of a patient is also provided. The system includes first and second instruments sized and shaped for introduction into the vessel of the patient; and a processing system communicatively coupled to the first and second instruments and a display device.

The invention provides magnetic response composite hydrogel for bone defect integrated repair and a preparation method of the magnetic response composite hydrogel, and belongs to the technical field of medical materials. The composite hydrogel provided by the invention can efficiently inhibit the activity of tumor cells under sequential regulation and control of an external alternating magnetic field, and then provides a suitable microenvironment and key components for bone tissue regeneration, so that signal conversion and function connection from tumor killing to bone repair are realized. The material has good injectability and self-healing capacity, can fill irregular defects in a minimally invasive mode, has remarkable advantages in the aspects of simplifying clinical treatment procedures, shortening the treatment course, reducing the tumor recurrence risk and improving the repair quality, and provides a brand-new and integrated treatment strategy for tumor-related bone defects.

Computing systems and computer-implemented methods for removing brain stimulation artifacts in neural signals are disclosed. The method makes use of a matching pursuit algorithm to accurately extract the stimulation artifact. The disclosed method removes the stimulation artifact associated with individual stimulation pulses without needing additional information from previous stimulation pulses or other electrodes. The disclosed method is compatible for use with various stimulation frequencies, does not need any filtering, and can recover neural signals almost immediately after stimulation. The disclosed method is compatible for use in has great potential in closed-loop systems used in various neurological diagnostic and therapeutic procedures.

A system for closed-loop control of sub-perception spinal cord stimulation therapy is provided. The system includes an implantable pulse generator (IPG) with an evoked compound action potential (ECAP) recording module and accelerometer. A regression model maps accelerometer data to optimal stimulation parameters for consistent nerve activation. This enables closed-loop therapy in the sub-perception domain where ECAP features are not visually detectable. A clinician programmer applies the model and sub-perception dose to therapy programs deployed to the IPG. The model can be customized to each patient by collecting ECAP and accelerometer data. The mapping reconciles ECAP -based control between perception and sub-perception domains by supplementing unavailable ECAP data with accelerometer data. This improves stimulation therapies for patients receiving sub-perception and multi-sensor paresthesia treatments.

The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.

The invention discloses a numerical control full-automatic intervertebral disc protrusion reduction therapy machine (hereinafter referred to as a therapy machine), and belongs to special medical equipment for conservative treatment of head, neck, shoulder, back, waist and leg diseases caused by intervertebral disc protrusion, vertebral body slippage and spinal syndrome. According to the therapeutic machine, pneumoelectric integration and mechatronics are combined with digitization and intellectualization, various traditional effective manual reset technologies, massage manipulations and therapeutic manipulations which cannot be manually completed are integrated into a whole, and according to different types of diseases of patients, basic parameters for treating diseases obtained clinically and practically are combined into a whole according to different types of diseases of the patients. Various different treatment procedures are compiled, a modern digital technology is used for replacing a manual treatment method, and the precedent of conservative treatment of the protrusion of intervertebral disc and the spondylolisthesis is developed. Program operation is carried out under the prompt of computer voice, and music or songs are accompanied in the whole program running process.

A system and method for prostate cancer treatment under local anesthesia includes creating a superficial skin and subcutaneous block in a perineal area of a patient by administering a first anesthetizing agent; creating a deep nerve block under ultrasound guidance by administering a second anesthetizing agent, the second anesthetizing agent infiltrating cavernosal nerve bundle tissue and periprostatic space; and ablating prostate tissue. The office-based method, statistical models and computer generated treatment plans identify and ablate prostate tissue containing cancer through or via the perineum while preserving prostate function, and critical anatomical structures. Multiple technologies are integrated and processed to deliver a safe treatment procedure, under local anesthesia by integrating the information of magnetic resonance imaging and planning the ablative treatment using algorithms that ensure maximal precision in both killing cancerous tissue and preserving healthy tissue along with its corresponding function.

Devices, systems and methods for removal of a mitral valve clip and subsequent delivery of a mitral valve implantation in a mitral valve replacement procedure. A modular port accessory device having a distal connector configured to be compatible with corresponding connectors on an existing therapeutic device, wherein the port accessory can be selectively attached to a proximal end portion connector of a proximal end portion of a catheter assembly of an existing therapeutic device. The catheter assembly is introduced to a target site within the patient's anatomy, and remains in place throughout a multistep therapeutic procedure for use with other therapeutic devices, all while allowing hemostasis to be controlled during use ad interchange of multiple therapeutic devices.

An example method of cycling electric stimulation includes delivering, via an implantable device, electric stimulation to a patient in accordance with a first therapy program; monitoring, via the implantable device and while the electric stimulation is being delivered in accordance with the first therapy program, a biomarker, and responsive to determining the biomarker satisfies a threshold, delivering, via the implantable device, electric stimulation to the patient in accordance with a second therapy program that is different than the first therapy program.

The present invention provides: a biomarker for non-invasively or minimally invasively detecting liver disease with high accuracy; a kit, method and program using this biomarker for non-invasively or minimally invasively detecting liver disease with high accuracy; a data processing method for detecting liver disease with high accuracy using this liver disease non-invasive marker; and a data processing device for use in this data processing. More specifically, provided is a biomarker selected from the group consisting of SEQ ID NOs: 1 to 125. Moreover provided is a detection kit for liver disease which includes a nucleic acid capable of binding specifically to a specific miRNA. Further provided are: a method for assessing the presence or absence of liver disease or the risk or degree of progression thereof in a subject, and / or the degree of success of a procedure performed for treatment, the method including measuring a level of a biomarker in a biological sample from the subject, and comparing a measurement value of the biomarker with a reference value, where the biomarker is one or more of the biomarkers selected from the group consisting of SEQ ID NOs: 1 to 125; a program; a data processing method for detecting liver disease with high accuracy using this liver disease non-invasive marker; and a data processing device for use in this data processing.