39 results about "Therapeutic Procedure" patented technology

Described herein are therapeutic electrical muscle stimulation (EMS) apparatuses for the detection, diagnosis, treatment or prevention of a neurological disorder. These apparatuses (including EMS suits, user interfaces, and control systems, etc.) and methods may be used as part of a therapeutic or non-therapeutic procedure. For example, these methods and apparatuses may be part of an exercise or fitness and / or may be used as part of a therapy, such as in particular for physiotherapy and / or for treatment of a condition or a disease.

Systems and methods are provided for managing and reducing the severity or impact of a collision involving an apparatus secured to a table associated with a medical imaging and / or therapeutic gantry. Example systems are provided in which an apparatus is secured to the table such that a distal region of the apparatus extends beyond a longitudinal end of the table. A pivot joint associated with the apparatus is provided such that when a collision between the distal region of the apparatus and an object occurs due to motion of the table, the resulting force causes the apparatus to rotate relative to the pivot joint, thus passively accommodating the applied force and preventing, or reducing the likelihood of, mechanical buckling of the apparatus in the presence of the force. In some example embodiments, the apparatus is configured to rotate and / or translate as a result of the force applied during the collision.

The present embodiments relate generally to enabling an end user - e.g. medical physicists - to monitor radiation therapy and, with integration to the LINAC, adaptive radiotherapy. Embodiments record signals already released during radiotherapy, requiring no new irradiation of the patient for in vivo, in line, dose monitoring. Furthermore, as the transducers will be coupled to the patient with ultrasound gel, the present embodiments are not invasive to patients and will not introduce new discomfort during therapeutic procedures. The addition of the RiAD system provides the end user with additional information during the treatment of the patient, allowing for real-time beam tracking and dosimetry, enabling the end user to practice adaptive radiotherapy. The RiAD system enables the end user to ensure that proper dose delivery is occurring with each new beamlet and dose deposition, empowering them to adapt the medical treatment as it is performed and increase its precision in conventional electron beam radiotherapy, electron FLASH radiotherapy, and intraoperative electron beam radiotherapy.

The invention discloses an execution mechanism, system and control method of a natural orifice passing diagnosis and treatment robot. The robot executing mechanism comprises a first continuous body section and a second continuous body section which are mechanically coupled, reversible anchoring components are arranged at the far ends of the first continuous body section and the second continuous body section respectively, and the first continuous body section has active controllable bending capacity. The robot system comprises the robot executing mechanism and a driving and control module. By controlling the two reversible anchoring parts to anchor alternately and coordinating and driving the two continuous body sections to push alternately and relatively, the robot executing mechanism can achieve growth type movement in the cavity. According to the control method, through the circulation steps of outer anchoring, inner bending extending, inner anchoring and outer follow-up, the robot executing mechanism gradually goes deep into the narrow bent cavity. An intracavity supporting point can be dynamically established through an alternate anchoring mechanism, and the advancing stability and operation precision of the flexible instrument are improved.

A method of marker-less registration of a pre-obtained medical imagery three-dimensional virtual model of a subject with live imagery of the same subject obtained prior to or during a surgical or therapeutic procedure performed on the subject, comprising: scanning the subject using a time-of-flight sensor to generate a point cloud data set corresponding to a skin layer of the subject, obtaining live imagery of the subject via a camera; receiving the pre-obtained medical imagery three-dimensional virtual model of a subject; processing the skin layer point cloud data set and the three-dimensional virtual model to determine one or more corresponding anatomical features of the subject present in both the point cloud data set and the three dimensional virtual model; aligning the point cloud data set and the three-dimensional virtual model in co-registration by aligning the determined one or more corresponding anatomical features of the subject in co-registration with each other; and displaying the three-dimensional virtual model so aligned within the live imagery of the subject.

The application provides a magnetic response composite hydrogel for integrated repair of bone defects and a preparation method thereof, and belongs to the technical field of medical materials. The composite hydrogel can efficiently inhibit tumor cell activity under the time sequence regulation of an external alternating magnetic field, and then provide a suitable microenvironment and key components for bone tissue regeneration, so that signal conversion and function connection from tumor killing to bone repair are realized. The material has good injectability and self-healing ability, can minimally invasively fill irregular defects, and has significant advantages in simplifying the clinical treatment procedure, shortening the treatment course, reducing the risk of tumor recurrence and improving the repair quality, and provides a new and integrated treatment strategy for tumor-related bone defects.

Ultrasound transducer element arrays using acoustic ensonification drive patterns via a patient interface for sonosensitizer activation in sonodynamic therapy. Incoherent acoustic field generation varying phase, frequencies, and / or amplitude via controlled delivery of low intensity planar acoustic waves. Method includes generating a first and a second signal to generate respective acoustic ensonification drive patterns with phase, frequency, and amplitude and generating at least one relative phase, frequency or amplitude difference to generate a third incoherent acoustic ensonification pattern to activate a sonosensitizer. Calibration and complementary therapy procedures to improve cell susceptibility of cells to sonodynamic therapy are disclosed.

A tool to create virtual lesions inside a 3D lung tumor image. The image can be an MRI or CT image of a patient's lung to be treated. This virtual pre procedural ablation allows the operator to identify optimal ablation sites and select the optimal ablation parameters for the given anatomy. Also, the actual procedure will be performed with the lung parenchyma surrounding the tumor preventing ultrasound to penetrate beyond the tumor walls. A diagnostic mode will guide the operator to optimize ablation parameters. This virtual pre ablation, the parenchymal ultrasound barrier and the diagnostic catheter operation should enable the operator to conduct the therapeutic procedure safe, fast and effective.

Various example embodiments of the present disclosure provide systems and methods for the dynamic correction and reduction of thermal variations in skull-induced aberrations during a focused ultrasound therapy procedure. Unlike conventional approaches involving static corrections for skull-induced aberrations, various example embodiments of the present disclosure employ ultrasound detection and a skull thickness estimate from volumetric image data to intermittently and dynamically determine corrections for skull-induced aberrations, such that aberration correction reduction is updated intraoperatively and maintained despite local thermally-induced changes in the speed of sound of the local skull region due to intraoperative intracranial heating. Furthermore, in some example embodiments, a measure dependent on the speed of sound with the skull is intraoperatively determined and compared to a previously determined value of the measure to determine a change in the skull temperature, based on a pre-determined relationship between changes in the measure and changes in skull temperature.

A method of performing a therapeutic procedure includes navigating a therapeutic device to a location adjacent to target tissue, determining a first flow parameter within a blood vessel adjacent to the target tissue, applying neurostimulation to the target tissue and obtaining first images of blood vessels distal of the target tissue, applying therapy to the target tissue, applying neurostimulation to the target tissue, determining a second flow parameter within the blood vessel adjacent to the target tissue, comparing the second flow parameter to a flow parameter criteria, applying neurostimulation to the target tissue and obtaining second images of the blood vessels distal of the target tissue, comparing the first images to the second images to determine a vasoconstriction metric, and applying therapy to the target tissue if it is determined that the vasoconstriction metric satisfies a vasoconstriction criteria.

The present invention relates to a medical interventional catheter, which includes a catheter body with both diagnostic and therapeutic capabilities. The catheter body includes a distal functional member configured for image-based monitoring of a tubular lumen of interest and for release of a therapeutic source to a target location in the tubular lumen of interest. The therapeutic source includes therapeutic energy and / or a therapeutic substance. This interventional catheter with both diagnostic and therapeutic capabilities provides real-time image-based monitoring in a therapeutic procedure, making the procedure more accurate and effective.

Monitoring system (15) for monitoring a patient, in particular during a medical diagnostic or therapeutic procedure, comprising • a voice cloning device (10) with a voice generator (11) which is designed to replace a person's natural voice with a cloned foreign voice different from the person's voice, wherein at least two foreign voices are selectable, • a measuring unit (13) which is designed to record at least one physiological parameter of the patient, • an evaluation unit (14) which is designed to evaluate at least one measured physiological parameter of the patient, and • a control unit (12) which is configured to control the voice cloning device (10) in such a way that a foreign voice is selected or rejected depending on the result of the evaluation by the evaluation unit, in particular for the further operation of the voice cloning device (10).

A rapid, minimally invasive biomarker assay is disclosed for distinguishing between ductal carcinoma in situ (DCIS) and early-stage invasive ductal carcinoma (IDC). The assay can be used for diagnostics and prognostics, and for supporting the development of treatments, procedures, protocols, and therapeutics aimed at preventing the invasive progression of breast cancer.

A method of performing and assessing a therapeutic procedure includes navigating a therapeutic device to target tissue, transitioning the therapeutic device from a first, linear configuration to a second, deployed configuration such that a plurality of electrodes on the therapeutic device are in engagement with the target tissue, applying pulses of neurostimulation energy having at least two phases to target tissue via the plurality of electrodes, the neurostimulation energy including an anodal phase and a cathodal phase, wherein a phase of the neurostimulation is switched from anodal to cathodal or cathodal to anodal for each successive pulse, observing a physiological response to the neurostimulation energy indicative of a neural response, denervating the nerves of the target tissue, and applying the neurostimulation energy to the target tissue, wherein a physiological response less than a threshold is indicative of a successful denervation of the nerves of the target tissue.

An example method of cycling electric stimulation includes delivering, via an implantable device, electric stimulation to a patient in accordance with a first therapy program; monitoring, via the implantable device and while the electric stimulation is being delivered in accordance with the first therapy program, a biomarker; and responsive to determining the biomarker satisfies a threshold, delivering, via the implantable device, electric stimulation to the patient in accordance with a second therapy program that is different than the first therapy program.

The present invention is both a device and a method for verifying a subject's identity while using a medical device or undergoing a medical diagnostic or therapeutic procedure, particularly at home or at a remote location. The method and device can be used for inpatient and remote sleep and signal analysis with biometric identification. The present invention is further related to the devices and sensors used in executing the method, and includes various embodiments of a method of inpatient and remote sleep analysis.

Systems and method for performing a therapeutic procedure including navigating a therapeutic device to target tissue, applying a first stimulus to the target tissue via a stimulus delivery element to contract the target tissue about the therapeutic device, and applying a first therapy to the target tissue contracted about the therapeutic device to denervate the target tissue.

A device for diagnostic and therapeutic procedures in ophthalmology, configured to deliver a photothermal treatment as well as a photobiomodulation treatment tuned to specific chromophores. The device may include a confocal scanning ophthalmoscope and a spectrometric dosimetry channel and is equipped with several safety features including a continuous automatic scanning of the eye and the eyelids.

A method of evaluating a vessel of a patient is provided. The method includes outputting, to a display device, a screen display including: a visualization based on pressure measurements obtained from a first instrument and a second instrument positioned within the vessel of the patient while the second instrument is moved longitudinally through the vessel and the first instrument remains stationary within the vessel; and a visual representation of a vessel; receiving a user input to modify the visualization to simulate a therapeutic procedure; and updating the screen display, in response to the user input, including modifying the visualization based on the user input. A system for evaluating a vessel of a patient is also provided. The system includes first and second instruments sized and shaped for introduction into the vessel of the patient; and a processing system communicatively coupled to the first and second instruments and a display device.

The invention provides magnetic response composite hydrogel for bone defect integrated repair and a preparation method of the magnetic response composite hydrogel, and belongs to the technical field of medical materials. The composite hydrogel provided by the invention can efficiently inhibit the activity of tumor cells under sequential regulation and control of an external alternating magnetic field, and then provides a suitable microenvironment and key components for bone tissue regeneration, so that signal conversion and function connection from tumor killing to bone repair are realized. The material has good injectability and self-healing capacity, can fill irregular defects in a minimally invasive mode, has remarkable advantages in the aspects of simplifying clinical treatment procedures, shortening the treatment course, reducing the tumor recurrence risk and improving the repair quality, and provides a brand-new and integrated treatment strategy for tumor-related bone defects.

Computing systems and computer-implemented methods for removing brain stimulation artifacts in neural signals are disclosed. The method makes use of a matching pursuit algorithm to accurately extract the stimulation artifact. The disclosed method removes the stimulation artifact associated with individual stimulation pulses without needing additional information from previous stimulation pulses or other electrodes. The disclosed method is compatible for use with various stimulation frequencies, does not need any filtering, and can recover neural signals almost immediately after stimulation. The disclosed method is compatible for use in has great potential in closed-loop systems used in various neurological diagnostic and therapeutic procedures.

Aspects of the present disclosure are directed to methods of treating a patient diagnosed with an interstitial lung disease (ILD), comprising administering a pharmaceutical drug for treating the ILD in a treatment regimen effective to treat fibrosis, inflammation, and / or vasculopathy, and in conjunction with the administration of the pharmaceutical drug, engaging in a self-directed digital therapeutic program that treats patient anxiety relating to the administration of the pharmaceutical drug, wherein the engaging in the self-directed digital therapeutic program is effective to increase adherence to the treatment regimen. Suitable pharmaceutical treatments include those that are useful in the therapy of an ILD, including pharmaceutical treatments that are in some way disease-modifying and / or capable of altering the course or the pathology of the ILD or at least slowing its progression, such as such as an antifibrotic agent, an immunomodulatory imide drug (IMID) or an angiotensin II type 2 receptor agonist (ATRAG).

A system for closed-loop control of sub-perception spinal cord stimulation therapy is provided. The system includes an implantable pulse generator (IPG) with an evoked compound action potential (ECAP) recording module and accelerometer. A regression model maps accelerometer data to optimal stimulation parameters for consistent nerve activation. This enables closed-loop therapy in the sub-perception domain where ECAP features are not visually detectable. A clinician programmer applies the model and sub-perception dose to therapy programs deployed to the IPG. The model can be customized to each patient by collecting ECAP and accelerometer data. The mapping reconciles ECAP -based control between perception and sub-perception domains by supplementing unavailable ECAP data with accelerometer data. This improves stimulation therapies for patients receiving sub-perception and multi-sensor paresthesia treatments.

A system and method of performing a therapeutic procedure, where a first neural block stimulation signal is applied to a blood vessel wall via electrodes on a distal portion of a therapeutic device located within the blood vessel, a change in vascular tone of the blood vessel is detected, and a therapy is applied to sympathetic nerves proximate the electrodes.

The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.

The invention discloses a numerical control full-automatic intervertebral disc protrusion reduction therapy machine (hereinafter referred to as a therapy machine), and belongs to special medical equipment for conservative treatment of head, neck, shoulder, back, waist and leg diseases caused by intervertebral disc protrusion, vertebral body slippage and spinal syndrome. According to the therapeutic machine, pneumoelectric integration and mechatronics are combined with digitization and intellectualization, various traditional effective manual reset technologies, massage manipulations and therapeutic manipulations which cannot be manually completed are integrated into a whole, and according to different types of diseases of patients, basic parameters for treating diseases obtained clinically and practically are combined into a whole according to different types of diseases of the patients. Various different treatment procedures are compiled, a modern digital technology is used for replacing a manual treatment method, and the precedent of conservative treatment of the protrusion of intervertebral disc and the spondylolisthesis is developed. Program operation is carried out under the prompt of computer voice, and music or songs are accompanied in the whole program running process.