758 results about "Prosthetic graft" patented technology

The invention belongs to the technical field of artificial prosthesis materials, and particularly relates to a medical implant with a lithium disilicate coating and a preparation method thereof, and the preparation method comprises the following steps: (1) placing a prefabricated matrix in a high-temperature environment for staged sintering, and then carrying out surface polishing, cleaning and drying treatment; (2) mixing lithium ethoxide and tetraethoxysilane at room temperature, and reacting for 2-4 hours while stirring to obtain lithium disilicate sol; the preparation method comprises the following steps: preparing a prefabricated substrate, soaking the prefabricated substrate in lithium disilicate sol for 3-7 minutes, performing sol permeation for 3-10 minutes under the negative pressure of more than 30 mm Hg, adding an ethanol water solution to initiate gelation reaction, taking out the prefabricated substrate after the reaction is completed, drying and sintering to obtain the medical implant with the lithium disilicate coating. According to the method, the uniform and continuous lithium disilicate coating which is not easy to fall off can be formed on the surface of the prefabricated matrix of the implant, so that the surface performance of the implant is improved, and the osteogenesis promoting performance and the angiogenesis promoting performance of the implant are optimized.

A prosthetic heart valves including an annular frame and one or more detachable outer skirts and methods associated therewith are disclosed. The frame includes a plurality of interconnected struts and one or more outer skirts releasably attached to an exterior surface of the frame. In some examples, an outer skirt is attached to the frame via at least one retaining suture formed by a plurality of stitches looped around a pull suture. Removal of the pull suture from the suture line enables the outer skirt and frame to separate as the stitches are pulled through openings in the outer skirt and remain attached to the frame. Removability of the outer skirt can facilitate improvements in implant and explant procedures of the prosthetic valves, such as, for example, valve-in-valve procedures.

An adaptor for a dental implant abutment includes a body extending along a longitudinal axis between a proximal end and a distal end. The body has a longitudinally extending bore extending from the proximal end for sliding receipt of a post of a dental implant abutment. The body has a distal shaft for inserting into a dental prosthetic, and the distal shaft tapers in outer diameter going towards the distal end. The body has proximal flange for securing between the dental prosthetic and the dental implant abutment. The proximal flange has a first ledge for abutting the dental implant abutment and a second ledge for abutting the dental prosthetic, and the second ledge tapers in outer diameter going towards the distal end.

Devices and methods for providing a pathway for fluid to flow around a main lumen of a guide catheter are disclosed. As one example, a delivery apparatus can include a handle including an outer housing and a flush port coupled to the outer housing, a shaft extending distally from the handle, and a main lumen extending axially through the shaft, where the main lumen is fluidly coupled to the flush port via a flush lumen extending between the flush port and the main lumen. The delivery apparatus can further include at least one axially extending channel fluidly coupled to and radially offset from the main lumen, the channel extending between a first location that is adjacent to the flush lumen and a second location that is adjacent to a distal end of the shaft.

The invention relates to a tibial plateau prosthesis. The tibial plateau prosthesis mainly comprises a tibial spacer, a tibial plateau and a sleeve. The tibia gasket is provided with a first fixing block and three arc-shaped holes, and movable second fixing blocks are arranged in the holes. The tibial plateau comprises a plateau support with open holes and a shell, and the open holes are formed in the side portion and the bottom of the shell. The screw penetrates through the gasket and the platform support to be inserted into the shell, and outer threads of the screw are meshed with inner threads of the sleeve. The sleeve moves upwards and extends out of the side hole of the shell through a hinged connecting rod system to penetrate into the medullary cavity to enhance fixation. A spring is arranged in the screw to drive the first pushing part and can be matched with the sleeve to prevent downward movement; and meanwhile, the second pushing part in the screw can extend into the medullary cavity from the bottom through threads. The design realizes multidirectional fixation and improves the stability of the prosthesis.

Prosthetic heart valves and methods for assembling prosthetic heart valves are disclosed. As one example, a prosthetic heart valve includes a frame, commissure support elements, and leaflets, each leaflet comprising a body and opposing commissure tabs, each commissure tab folded over from a corresponding body to form a bend between the commissure tab and body and arranged adjacent to another folded commissure tab of an adjacent leaflet to form a pair of commissure tabs that is coupled to one commissure support element to form a commissure. Each commissure tab is secured to the commissure support element via a reinforcement member positioned against the commissure tab, adjacent to the bend, and secured to and / or at least partially wrapped around the commissure tab and the commissure support element, the reinforcement member comprising a flexible body and a more rigid, central portion, the central portion positioned along a height of the commissure tab.

A prosthetic valve includes a radially expandable and compressible frame, a leaflet assembly comprising a plurality of leaflets coupled to the frame, and an outer skirt positioned around an outer surface of the frame. The outer skirt includes a tissue layer and a non-tissue layer. The tissue layer has a fibrous side and a smooth side. The non-tissue layer is coupled to the smooth side of the tissue layer. The outer skirt is positioned so that the fibrous side of the tissue layer faces away from the frame and the non-tissue layer faces towards the frame.

A delivery device for percutaneously delivering a stented prosthetic heart includes a sheath, a handle, and adjustment device including a fine adjustment mechanism, and an outer stability shaft. The sheath defines a lumen and is configured to compressively constrain the stented prosthetic heart valve. The handle is coupled to the proximal portion of the sheath and includes an actuator mechanism coupled to a proximal portion of the sheath that is configured to selectively move the sheath relative to the housing to release the stented prosthetic heat valve. The adjustment device is coupled to the handle and includes an adjustment lumen through which the sheath and the handle slidably extend. The outer stability shaft is coupled to the adjustment device. The fine adjustment mechanism is configured to selectively move the handle and the sheath relative to the adjustment device and the outer stability shaft.

According to one example, a for revision knee arthroplasty is disclosed. According to this example, the method can include shaping a bone of a patient to create one or more recesses therein, selecting a stem provisional, disposing the stem provisional within the one or more recesses, and assembling in vivo the stem provisional with both a first provisional component configured to simulate a shape of one of a tibial tray implant or a femoral implant and a second provisional component configured to simulate a shape of at least one of a sleeve component, a cone component or a keel component of an implant.

The invention of the gradient porous structured sacral prosthesis and the manufacturing process aims to create an alternative replacement for bone loss in patients who require bone replacement. The gradient porous structured sacral prosthesis consists of an artificial bone fragment, a metal rod, and a set of screws for fixing the fragments. The manufacturing process consists of seven steps: Identifying the position and boundaries of the bone, First-step topology optimization, Second-step topology optimization, Defining the structural pattern and unit cell size, Designing the artificial bone implant, Mechanical performance testing of the implant, and Fabrication of the sacral implant. The devices and processes according to the present invention are clearly sequenced and characterized. Modification or change in the manufacturing sequence or use may reduce the capabilities of the present invention or make it unusable for the purposes of the present invention.

The invention provides a tibial prosthesis which comprises a tibial platform provided with a containing groove and a communicating groove, the containing groove is communicated with the upper surface of the tibial platform, and the communicating groove is communicated with the groove bottom wall of the containing groove and the lower surface of the tibial platform; the gasket structure is arranged in the containing groove in a floating mode in the vertical direction; the bone growth body is connected to the lower portion of the gasket structure and located in the communicating groove, and the gasket structure can drive the bone growth body to penetrate out of the tibial plateau downwards when floating in the vertical direction. According to the technical scheme, the problem that in the prior art, the time needed for combining the sclerotin and the prosthesis of a patient is long can be effectively solved.

The invention relates to an intracavity implantation system which comprises an intracavity prosthesis, the intracavity prosthesis has a radial expansion state and a radial contraction state, the intracavity prosthesis comprises a covered stent, a valve prosthesis and a flexible connecting pipe, the covered stent is of a tubular structure and comprises a main body section and a reducing section which are communicated with each other, and the valve prosthesis is arranged in the main body section. The main body section and the reducing section are arranged in the axial direction of the covered stent, the cross section area of the near end of the reducing section is smaller than that of the far end of the reducing section, the covered stent is further provided with a window penetrating through the side wall of the covered stent, and at least part of the area of the window is located in the reducing section; the valve prosthesis comprises a valve support and an artificial valve leaflet connected to the interior of the valve support. The flexible connecting pipe is of a tubular structure defined by a flexible film, the far end of the flexible connecting pipe is connected with the reducing section, the near end of the flexible connecting pipe is connected with the valve prosthesis, and the two axial ends of the flexible connecting pipe are communicated with the covered stent and the valve prosthesis respectively. In the implanting process of the endoluminal prosthesis, the relative position of the valve prosthesis and the covered stent can be adjusted according to the lumen structure, and the endoluminal prosthesis can better adapt to various lumen structures. In addition, due to the arrangement of the flexible connecting pipe, the risk that the far end of the valve prosthesis is driven to expand and deform due to expansion of the covered stent can be reduced, force generated in the expansion process of the valve prosthesis is not prone to being transmitted to the covered stent, and therefore the risk that coronary blood flow is blocked due to expansion of the near end of the covered stent can be reduced.

Systems and methods for anchoring and restraining gastrointestinal prostheses are disclosed. In various examples, the systems and methods include securing a gastrointestinal device within a patient's anatomy by extending an anti-migration anchor through a plurality of portions of the gastrointestinal device to couple together the plurality of portions of the gastrointestinal device. In some examples, the anti-migration anchor extends through tissue situated between the plurality of portions of the gastrointestinal device.

Provided is a prosthetic valve replacement system. A hoop member is at least partially disposed on a valve clamping mechanism. A valve clamping and securing mechanism is configured to present a first form and a second form, and the second form is present after the first form. When the valve clamping and securing apparatus is in the first form, the valve clamping mechanism is configured to capture and clamp autologous valve leaflets. After the radial expansion of a valve stent, the valve clamping and securing apparatus is in the second form.

A flanged healing abutment for securing to an implant that has a bone graft. The flexible flange extends out laterally from the healing abutment body to contact the adjacent gingiva. The flange securely contacts the gingiva in a manner that contains the bone graft, and prevents bacterial infection of the bone graft. The flanged abutment is also able to form gingival emergence profiles. A method for securing a prosthesis to an implant utilizing a flanged healing abutment is also provided.

The invention provides a femoral stem prosthesis. The femoral stem prosthesis comprises a femoral stem, an expansion component and a sleeve. The femoral stem is composed of an upper stem body and a replaceable lower stem body, and threads are arranged in the femoral stem. The expansion part is located in the upper handle body and comprises a screw, a rotating disc and a multi-layer pushing structure. The screws are connected with the upper and lower handle bodies through threads; and the turntable is in threaded engagement with the screw and can drive the first pushing part along the first guide rail during rotation. Ratchets are arranged in the rail component and meshed with the pawls of the second pushing part, and an open hole is formed in the side of the second pushing part. And the sleeve is linked with the expansion component through the fifth pushing part, the fourth pushing part and the third pushing part. During implantation, the second pushing part outwards pushes the sleeve to be attached to the wall of the medullary cavity, the internal pushing structure acts successively under the counter-acting force, and finally the first pushing part is separated from the second pushing part. Then bone cement is injected through a sleeve micropore, and the stability of the prosthesis is enhanced. By means of the design, intraoperative adaptation and stable filling are achieved.

A device and method of inhibiting and preventing damage to leaflets during the crimping of a prosthetic valve, and / or facilitating the folding of the leaflets during the crimping of a prosthetic valve.

A prosthetic acetabular liner including a wall that extends from an apex portion to a circumferential rim portion, the wall having: a convex outer surface; a threaded spigot extending outwardly from the apex portion; a concave inner bearing surface; and an opening surrounded by the circumferential rim portion. The liner is rotatably insertable into an acetabular outer shell having a corresponding threaded apical hole, and rotation of the liner in the shell causes the threaded spigot to engage the threaded apical hole and thereby draw the liner into the shell.

In some examples, a method of manufacturing a prosthetic heart valve includes providing a stent and a valve assembly, the valve assembly including at least one of an inner cuff and an outer cuff, and a plurality of leaflets, sputter coating a layer of one or more target materials onto a surface of at least one component selected from the plurality of leaflets, the inner cuff and the outer cuff, and coupling the valve assembly to the stent.

A prosthetic heart valve for the treatment of structural heart disease wherein the prosthetic heart valve includes an expandable frame that a) has an open cell geometry in the frame of the prosthetic heart valve that can be used to reduce delivery system size, b) has high radial strength, c) has improved restoration of the physiologic EOA, d) has lower recoil, e) has little or no longitudinal foreshortening, f) allows for proper placement of the bioprosthetic valve in relation to the native commissures of the valve, h) has symmetrical and cylindrical expansion of the prosthetic valve resulting in lower rates of leaflet thrombosis and structural valve deterioration, and / or i) prevents allergic response and restenosis associated with nickel content.

An implantable prosthetic valve includes a radially collapsible and expandable annular frame having three commissure attachment posts and four rows of circumferential struts. The rows include a first row, a second row downstream of the first row, a third row downstream of the second row, and a fourth row downstream of the third row and defining an outflow end of the frame. Each row of circumferential struts includes angled struts arranged in a zig-zag pattern. A leaflet structure includes three leaflets forming three commissures, each commissure being connected to one of the commissure attachment posts only at locations along the commissure attachment posts between a first plane that is perpendicular to a longitudinal axis of the frame and intersects crowns of the third row of struts and a second plane that is perpendicular to the longitudinal axis and intersects crowns of the fourth row of struts.

The invention discloses a composite amnion for improving contracture after tissue repair and a preparation method of the composite amnion. The composite membrane comprises a recombinant humanized collagen nanofiber membrane located in the middle layer and human decellularized amniotic membranes attached to the two faces of the nanofiber membrane. The composite membrane is prepared by preparing a recombinant humanized collagen nanofiber membrane through an electrostatic spinning technology and pressing the recombinant humanized collagen nanofiber membrane and a human decellularized amniotic membrane. The composite membrane has excellent mechanical properties and biological activity. Animal experiment results show that the composite film can effectively inhibit capsule contracture induced by radiotherapy, and the comprehensive effect of the composite film is obviously superior to that of a single-component material in the aspects of inflammation resistance, fibrosis resistance, degradation speed delaying, capsule compliance improving and the like. The composition can be used for improving the capsule contracture of the breast prosthesis, especially the capsule contracture induced by radiotherapy.

The present disclosure relates to a prosthesis (400) configured for implantation in a carpometacarpal joint in the wrist, the prosthesis comprising a first and a second implant part member (405a,b) configured to be screwed into a radius and metacarpal bone respectively. Each implant part member (405a,b) comprising an articulation member (420a,b) configured to be received in the bone fixation member (410a,b) in a releasable manner. The articulation members (420a,b) comprise orientation pins (423) configured to be inserted into bore sections of the bone fixation members 410a,b. When seated in the bore sections, the first portions of the articulation members (420a,b) with the orientation pins (423) are substantially centered along the central axes of the bone fixation members (410a,b), thereby forming common central axes extending through the bone fixation members (410a,b) and the articulation members (420a,b). The radius articulation member (420a) comprises a replacement articular surface configured for articulation with a replacement articular surface located on the metacarpal articulation member (420b). The radius replacement articular surface has (420a) a configuration that is asymmetric about the common central axis of the radius bone fixation (410a) and articulation members (420a). The bore sections have cross-section (419) extending perpendicularly to the central axis defining a first polygonal outline (429). The orientation pins (423) have cross-sections defining a second polygonal contour line, such that when the orientation pins (423) of the articulation members (420a,b) are seated in the bores of the bone fixation members (410a,b), rotation of the articulation members (420a,b) in relation to the bone fixation members (410a,b) is prevented.

An acetabular cub system is configured to be secured to a pelvis and may include an acetabular cup and a plurality of bone fasteners. The acetabular cup may include a bone engaging surface and an articulating surface, as well as a plurality of lobed fastener apertures extending from a first opening at the articulating surface to a second opening at the bone engaging surface. The plurality of bone fasteners may be insertable through the lobed fastener apertures to secure the acetabular cup to the pelvis. Each of the plurality of lobed fastener apertures may include a central aperture configured to receive a first bone fastener of the plurality of bone fasteners and one or more aperture lobes intersecting with the central aperture configured to receive a second bone fastener of the plurality of bone fasteners. The central aperture may be larger than the one or more aperture lobes.

The subject of the invention is a delivery system for delivering a self-expanding endoluminal prosthesis to the patient's ascending aorta and aortic valve, the system comprising: - an inner tube (33), extending along a longitudinal Y axis of the delivery system (100), from an atraumatic distal tip (27) to a handle (37); - a metal tube (32), slide-fitted on the inner tube (33), and extending from the internal space of the distal tip (27) to a handle (37); - an outer tubular catheter shaft (22) slide-fitted on the metal tube (32), the catheter shaft (22) is brought out from the handle (37) and is terminated by a capsule (20), containing inside the radially compressed on the metal tube (32), self-expanding endoluminal prosthesis (1) having defined construction and covered at least partially by a coating (16), - the capsule (20) has closed position when is closed by the tip (27) and has open position when the capsule (20) and the tip (27) are displaced relative to each other; wherein the distal part of the metal tube (32) is equipped with receiving means (41, 42) on which the distal locking means (7) of prosthesis (1) are removably embedded and blocked in the inner space of the tip (27) and the delivery system (100) comprises also removable holding means (45, 45') retaining the proximal locking means (9) of the prosthesis (1), so that when the capsule (20) is in its fully open position, the prosthesis (1) is still maintained partially compressed, holding its crimping length.

Valve positioning structures for use in a prosthetic heart valve delivery apparatus and associated methods. The delivery apparatus can include a balloon coupled to a distal end portion of a shaft and a valve positioning structure can be disposed around the balloon, and a prosthetic heart valve can be crimped around the balloon and the valve positioning structure. The valve positioning structure can include a support structure, such as a frame or a braided wire mesh, which can be coated with a polymeric coating to protect the balloon and the prosthetic valve. In some examples, the polymeric coating is an open-cell polymeric coating. In some examples, the polymeric coating is a closed-cell polymeric coating. In some examples, a webbing portion of the closed-cell polymeric coating spanning across the cells of the support structure can be formed while the support structure is in an at least partially expanded state.

Methods include tracking one or more of a leg length or an offset in a patient during a total hip arthroplasty (THA) procedure performed using a navigated surgical system, with an expandable trial femoral assembly. Certain methods include registering a pelvis of the patient to the navigated surgical system; and in various embodiments measuring a leg length or registering a femur to the navigated surgical system. An expandable trial femoral assembly is affixed to a prepared and broached femur of the patient; and the expandable trial femoral assembly is reduced into an acetabular prosthesis. A navigated driver may then be used to adjust an expansion extent of the expandable trial femoral assembly. The navigated surgical system may measure the leg length and the offset in the patient based on the movement of a reference element of the femur relative to a reference element of the pelvis.

Packaging for prosthetic heart valves including an assembly for stabilizing dry prosthetic tissue implants such as heart valves during storage. The packaging assembly includes a primary sterile barrier that permits gas sterilization of the tissue implant, and a secondary sterile barrier that also prevents oxidation of the implant during long-term storage. Tissue heart valves may be placed or suspended within a cavity of an inner rigid tray with a gas-permeable lid sealed thereon, and a cap placed over the cavity to limit movement of the valve therein. The inner tray is placed within an outer sterile barrier, such as another rigid tray or a flexible pouch, and the assembly is then sterilized. The outer sterile barrier may include a double seal so that a first gas-permeable seal can be closed for sterilization, after which a second gas-impermeable seal can be closed to seal out any further oxygen contact with the tissue implant. Alternatively, the inner tray may be placed within a sterile pouch and the assembly gas-sterilized, and then the entire assembly is placed within another pouch that provides an impermeable barrier to the surrounding atmosphere to prevent oxidation of the tissue implant.

An implant assembly for a long bone is adapted to support an exo-prosthesis. The assembly includes a stem, a subdermal component and a percutaneous post. The stem has a proximal end that is adapted to be received in a surgically prepared medullary canal of the long bone, and a distal end having a surface that is adapted to promote bone ingrowth. The subdermal component includes a proximal portion that is adapted for attachment to the distal end of the stem, and a fixation surface that is adapted to promote soft tissue fixation. The percutaneous post has a proximal end that is adapted to be attached to the subdermal component.

The invention relates to a heart valve docking device and a system for treating a native valve of a patient. In various embodiments, the device is configured to repair a native heart valve or to secure a prosthetic heart valve within a native valve of a patient's heart. An embodiment of the apparatus includes at least an upper coil and a lower coil, wherein the apparatus is configured to assume an axially expanded state in which the entire upper coil is positioned on a first side of the lower coil relative to the central axis and an axially compressed state in which at least a portion of the upper coil is positioned on a second side of at least a portion of the lower coil opposite the first side relative to the central axis.