31 results about "Distal embolization" patented technology

An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. Obturator assemblies and infusion catheter assemblies are provided to be used with the evacuation sheath assembly. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped and the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly. If necessary to increase retrograde flow, the coronary sinus may be at least partially occluded. Alternatively, antegrade flow may be permitted while flow is occluded at the treatment site.

Methods and assemblies are described for capturing embolic material in a blood vessel or other body cavity during cardiovascular or valve replacement and repair surgery, wherein access is provided through the apical area of the patient's heart. The distal embolic protection assembly generally comprises a sleeve having a lumen, an actuating member having proximal and distal ends, wherein the actuating member is movably disposed within the lumen, and a filter assembly coupled to the distal end of the actuating member. The filter assembly generally comprises a porous bag having an open proximal end, a collapsible and expandable frame that is coupled to the open proximal end of the porous bag, and at least one support spine disposed at least a part of the longitudinal axis of the porous bag. The porous bag is configured such that it permits blood to perfuse freely through while capturing embolic material and other debris.

Devices for excluding aneurysms and treating atherosclerotic disease, for intra-aneurysmal occlusion; and devices for preventing distal emboli. The devices are generally pliable and collapsible thin film devices which can be delivered via a microcatheter into the desired location where they are deployed and undergo either a shape memory phase transformation or in situ polymerization to assume the stable configuration of a permanent endoluminal prosthesis. Prior to being caused to assume their final shape, the devices remain soft, collapsible and pliable to ensure atraumatic delivery through the vascular system. Upon reaching the endoluminal defect in the vessel, the device is extruded from the microcatheter. Devices are also provided for retrieving clots.

A method for reducing distal embolization during insertion of devices to treat plaque, thrombi and other intravascular occlusions. Using a guide catheter, a guidewire is delivered to a site proximal to the lesion. An aspiration catheter is then introduced over the guidewire, and the two are moved together in a distal to proximal direction across the occlusion. The aspiration catheter is then moved in a proximal to distal direction while continuously aspirating, which prevents embolization of any particles which may be created during the crossing of the guidewire.

An ablation catheter system for capturing and removing necrotic tissue and thrombi generated during an ablative procedure is disclosed. The catheter typically includes an elongate member, a filtration assembly disposed within the distal region, and an ablation instrument at the distal end. Alternatively, the ablation instrument is carried on the distal end of an ablation catheter, which is disposed within a lumen of the catheter system. The catheter may further include an aspiration port and lumen. Methods of using the devices in preventing distal embolization during ablative procedures are disclosed.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter. The constrictor / occluder is mounted at the distal end of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during extracranial or intracranial carotid procedures or vertebral artery procedures by reversing blood flow in an internal carotid artery, an external carotid artery, and / or a common carotid artery toward the subclavian artery are disclosed.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter. The constrictor / occluder is mounted at the distal end of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices are disclosed for preventing distal embolization during extracranial or intracranial carotid artery, vertebral artery, or coronary artery procedures, or procedures involving any vessel having collateral flow by reversing flow in the diseased vessel.

An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. The evacuation sheath assembly includes an elongated tube defining an evacuation lumen having proximal and distal ends. A proximal sealing surface is provided on a proximal portion of the tube and is configured to form a seal with a lumen of a guided catheter. A distal sealing surface is provided on a distal portion of the tube and is configured to form a seal with a blood vessel. Obturator assemblies and infusion catheter assemblies are provided to be used with the evacuation sheath assembly. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. Normal antegrade blood flow in the blood vessel proximate to the stenosis is stopped and the stenosis is treated. Retrograde blood flow is induced within the blood vessel to carry embolic material dislodged during treating into the evacuation sheath assembly. If necessary to increase retrograde flow, the coronary sinus may be at least partially occluded. Alternatively, antegrade flow may be permitted while flow is occluded at the treatment site.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter has a lumen communicating with a port at its distal end. The lumen and port are adapted for introduction of therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter, into a vertebral or basilar artery. The constrictor / occluder is mounted proximal to the port of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during vertebral and / or basilar procedures by reversing blood flow in the vertebral artery toward the subclavian artery are disclosed.

Systems, methods, and devices for the treatment of acute ischemic stroke that provide immediate blood flow restoration to a vessel occluded by a clot and, after reestablishing blood flow, address the clot itself. Immediate blood flow restoration advantageously can facilitate natural lysis of the clot and also can reduce or obviate the concern for distal embolization due to fragmentation of the clot. Several embodiments of the invention provide for progressive, or modular, treatment based upon the nature of the clot. For example, the progressive treatment can comprise a three-step progressive treatment process that includes immediate restoration of blood flow, in-situ clot management, and / or clot removal depending on the particular circumstances of the treatment. The in-situ clot management can include, for example, lysis and maceration. The progressive, or modular, treatment can be provided by a system or kit of one or more treatment devices.

A directional balloon is provided that can be used for a medical intervention of a body lumen. In one aspect, the directional balloon inflates in a distal to proximal direction and deflates in a proximal to distal direction. In another aspect, the directional balloon inflates in a proximal to distal direction and deflates in a distal to proximal direction. The directional balloon is capable of providing an occlusive seal to protect against embolization. A suction catheter with a control means is provided to provide suction in a controlled fashion in a body lumen. The suction catheter is used during periods of a medical intervention that risks distal embolization. When turned on, the suction catheter is capable of removing unwanted materials. The suction means could be operated by a control means.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter. The constrictor / occluder is mounted at the distal end of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices are disclosed for preventing distal embolization during extracranial or intracranial carotid artery, vertebral artery, or coronary artery procedures, or procedures involving any vessel having collateral flow by reversing flow in the diseased vessel.

Systems, methods, and devices for the treatment of acute ischemic stroke that provide immediate blood flow restoration to a vessel occluded by a clot and, after reestablishing blood flow, address the clot itself. Immediate blood flow restoration advantageously can facilitate natural lysis of the clot and also can reduce or obviate the concern for distal embolization due to fragmentation of the clot. Several embodiments of the invention provide for progressive, or modular, treatment based upon the nature of the clot. For example, the progressive treatment can include immediate restoration of blood flow, in-situ clot management, and / or clot removal depending on the particular circumstances of the treatment. The in-situ clot management can include, for example, lysis, maceration, and / or removal.

An endoluminal catheterization device for providing protection against distal embolization of atherosclerotic debris and thrombi emboli resulting from an endoluminal catheterization procedure. The device is adapted to the new TAVI / PAVI methods to prevent the severe risk of brain embolization and stroke. The embolization protection device may also be an integral part of any other intra-luminal treatment or diagnostic device that may induce embolization, such as a balloon, stent, TAVI or atherectomy.

The invention relates to the technical field of medical apparatuses, in particular to a sectional thrombus extraction device and a thrombus extraction method making use of the thrombus extraction device. The sectional thrombus extraction device comprises a vascular thrombus extraction stent and a conveying system which is connected to one end of the vascular thrombus extraction stent, wherein the vascular thrombus extraction stent is of an auto-expansion meshed pipe structure which is formed by mutually connecting a plurality of unit grids; radial clearances are formed in the meshed pipe structure; by virtue of the radial clearances, the meshed pipe structure is divided into a plurality of sectional structures which are sequentially connected, so that the circumstance that a thrombus is divided by excessive meshes is avoided, and subsequently, the relative integrity of the thrombus is maintained, the risk of distal embolization in the case that the thrombus breaks off is reduced and rapid and reliable thrombus extraction is achieved; due to the design of the sectional structure, the softness and conveying performance of the thrombus extraction stent are enhanced, and the thrombus extraction stent can be conveyed to a blood vessel which is relatively thin in distal end; and the sectional meshed stent structure is low in metal coverage rate and relatively low in injury on endangium in a thrombus extraction process, and related complications caused by mechanical thrombus extraction are reduced.

A catheter device fur diagnostic vascular treatment and / or therapeutic vascular treatment of a subject's vasculature having a blunt, atraumatic (non-traumatic) distal tip and orifice edge to the catheter. This will eliminate or mitigate catastrophic complications caused by contemporary catheters such as vascular dissection, thrombosis, distal embolization and vessel occlusion. The catheter tip can be shaped in various ways with solid material (compressible or non-compressible) or balloon inflation devices to create a blunt, atraumatic (non-traumatic) tip and orifice, and may include a set-back region as well.

A device and method for balloon and stent angioplasty for treating atherosclerosis with a distal embolization protection component. The device includes an endoluminal dilatation balloon formed on a shaft having at least one lumen, a flexible filter mounted on the shaft, distal to the balloon and a filter deployment memory ring circling the proximal opening of the flexible filter for the purpose of controlling deployment and collapsing of the filter. When the endoluminal dilatation balloon is inflated for the purpose of dilating plaque that is blocking a blood vessel, the flexible filter deployed prior to balloon inflation, traps atherosclerotic debris and thrombi emboli that are released from the plaque, thus allowing blood flow to continue without interference during the angioplasty procedure. At the end of the procedure the flexible filter, containing the debris, is pulled and collapsed into a small profile and is pulled out of the artery as an integrated unit with the balloon. The device may or may not have a stent pre-crimped over the dilatation balloon.

A medical device having a catheter and one or more expandable constricting / occluding members. The catheter is adapted for use with therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter. A first constrictor / occluder mounted at the distal end of the catheter is adapted for placement in a brachiocephalic or subclavian artery. A second constrictor mounted proximal to the first constrictor / occluder is adapted for placement in the descending aorta. Pressure measuring devices may be included, and filters may be used to capture embolic debris. Methods of using the devices for preventing distal embolization during extracranial or intracranial carotid procedures or vertebral artery procedures by augmenting collateral cerebral circulation by coarctation of the aorta to enhance reversal of blood flow in an internal carotid artery, an external carotid artery, and / or a common carotid artery toward the subclavian artery are disclosed.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter has a lumen communicating with a port at its distal end. The lumen and port are adapted for introduction of therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter, into a vertebral or basilar artery. The constrictor / occluder is mounted proximal to the port of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during vertebral and / or basilar procedures by reversing blood flow in the vertebral artery toward the subclavian artery are disclosed.

The invention provides a medical device having a catheter and one or more expandable constricting / occluding members. The catheter has a lumen communicating with a port at its distal end. The lumen and port are adapted for introduction of therapeutic or diagnostic devices, including an angioplasty / stent catheter and an atherectomy catheter, into a vertebral or basilar artery. The constrictor / occluder is mounted proximal to the port of the catheter. Manometers may be mounted distal to one or more constrictors for measuring pressure distal to the constrictor(s). Methods of using the devices for preventing distal embolization during vertebral and / or basilar procedures by reversing blood flow in the vertebral artery toward the subclavian artery are disclosed.

The invention provides a thrombus taking device applied to artery and venous thrombus, and belongs to the field of a medicine appliance. The thrombus taking device applied to artery and venous thrombus comprises a guide wire, a guiding catheter, a collecting assembly and an inner sheath, wherein the guiding catheter and the collecting assembly are respectively arranged on the guide wire in a sleeving way; the inner sheath is arranged on the guiding catheter in a sleeving way; the collecting assembly has a folding state extending into the guiding catheter and an unfolding state extending out toan upstream position of the guiding catheter; the collecting assembly comprises a filtering screen sleeve, an elastic framework and a constraint wire; the filtering screen sleeve is provided with a sealed opening end and an open opening end; the sealed opening end is positioned in an upstream position of the open opening end and is connected with the guide wire; the elastic framework is connectedwith the open opening end; the head end of the constraint wire is connected with the elastic framework; and the tail end of the constraint wire is arranged in the guiding catheter in a penetrating way. The thrombus taking device can be used for taking out thrombi and tumor emboli, and can be used for effectively preventing the risk of generation of distal embolization in in the thrombus taking process and in various intracavitary therapy processes such as endovascular balloon dilatation, angioplasty, thrombectomy and stent implantation.

A catheter device is disclosed comprising; an elongate sheath (503) with a lumen and a distal end for positioning at a heart valve (6), an embolic protection device (200) for temporarily positioning in the aortic arch for deflection of embolic debris from the ascending aorta to the descending aorta, said embolic protection device is connectable to a transluminal delivery unit (130) extending proximally from a connection point (131), and having: a frame with a periphery, a blood permeable unit within said periphery for preventing embolic particles from passing therethrough with a blood flow downstream an aortic valve into side vessels of said aortic arch to the brain of a patient, and at least one tissue apposition sustaining unit (300, 350) extending from said catheter, into said aortic arch, and being attached to said embolic protection device at a sustaining point (502), for application of a stabilization force offset to said connection point at said embolic protection device, such as at said periphery, and for providing said stabilization force towards an inner wall of said aortic arch, away from said heart, and in a direction perpendicular to a longitudinal extension of said periphery, when said catheter device is positioned in said aortic arch, such that tissue apposition of said periphery to an inner wall of said aortic arch is supported by said force for improving stability and peripheral sealing. In addition related methods are disclosed.

An evacuation sheath assembly and method of treating occluded vessels which reduces the risk of distal embolization during vascular interventions is provided. A method of treating a lesion within a blood vessel, e.g., a coronary artery, includes advancing a sheath into the blood vessel, the sheath having a lumen extending to a port at a distal end of the sheath and further having an occlusive member within a distal region of the sheath. The occlusive member is then positioned within the blood vessel proximal to the lesion. Subsequently, the occlusive member is deployed, thereby stopping antegrade flow across the lesion. A contrast agent can then be infused through a port in the sheath. A dilation balloon is then advanced across the lesion. Suction is then applied to the lumen to induce retrograde flow across the lesion after dilating the lesion.

Devices and methods are disclosed for preventing distal embolisms during endovascular interventions. Representative devices are kits that include a first catheter comprising a proximal part and distal part having a principal through lumen, at least one lumen for filling at least one balloon, at least one inflated balloon that closes the lumen of the right or left carotid artery, and a proximal end configured to allow blood to flow through the principal lumen but to block the passage of emboli. The kits include a second catheter in the form of a single-lumen tube with a proximal end and a distal end. The proximal and distal parts of the first catheter may have diameters that are sufficient to allow passage through the lumen of the second catheter and may be sufficiently long when combined to allow at least the distal part of the first catheter to extend beyond the limits of the distal end of the second catheter, when the first catheter passes through the second catheter. Moreover, the internal diameter of the lumen of the second catheter may exceed the external diameter of the distal part of the first catheter.